30 results about "Vertebral basilar artery" patented technology

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor / occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and / or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.

The present invention provides a method and system for determining the cerebral hemodynamic model for depression, using carotid duplex ultrasound to establish percent stenosis of the extracranial right and left internal carotid arteries and transcranial Doppler ultrasound instrument to measure mean flow velocity within the cerebral including the right and left internal carotid arteries, right and left middle cerebral arteries, right and left anterior cerebral arteries, right and left posterior cerebral arteries, and basilar artery. The percent carotid stenosis and the mean flow velocity values in cerebral arteries are used to determine the cerebral hemodynamic model associated with depression in men and women, respectively.

A method for enhancing cerebral blood flow in a patient. The patient's baseline cerebral blood flow is measured. An artery of the patient is cooled or warmed to produce vasodilatation of the artery. The artery is typically one or more of the left or right common carotid artery, left or right internal carotid artery, left or right middle cerebral artery, anterior cerebral artery, left or right vertebral artery, or basilar artery. Vasodilatation enhances cerebral blood flow. The enhanced cerebral blood flow is measured after cooling or warming the artery. The enhanced cerebral blood flow is compared to the baseline cerebral blood flow. Cooling or warming is then adjusted as needed to achieve a desired enhancement in cerebral blood flow. Devices for cooling and warming are also described.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor / occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and / or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.

The Chinese medicine for treating dizziness caused by vertebro-basilar artery blood supply insufficiency as one dizziness treating Chinese medicine is prepared with 11 kinds of Chinese medicinal materials, including pinellia tuber, white atractylodes rhizome, gastrodia tuber, dried old orange peel, tuckahoe, etc. in certain weight proportion. It has facile materials, simple preparation process, low cost and high curative effect.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor / occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and / or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.

A flow diverter for implantation into a patient's vessel includes a distal annular support element and a proximal annular support element, the proximal and distal support elements supporting a longitudinally twisted diverter element. The flow diverter is designed to be disposed within a vessel and to impart a rotational or twisting motion to the flow of blood passing therethrough, thereby to reduce the pressure of blood at the center of the vessel. Such flow diversion can reduce the pressure of blood impinging upon an aneurysm at a bifurcation downstream of the vessel. The device can be particularly useful for the treatment of aneurysms occurring at the bifurcation between the basilar artery and the posterior cerebral arteries.

The present invention provides a method for determining the cerebral hemodynamic model for depression, using carotid duplex ultrasound to establish percent stenosis of a right external carotid artery and a left external carotid artery, and transcranial Doppler ultrasound instrument to measure mean flow velocity within the cerebral arteries including the right and left internal carotid arteries, right and left middle cerebral arteries, right and left anterior cerebral arteries, right and left posterior cerebral arteries, and basilar artery. Percent carotid stenosis and mean flow velocity values in cerebral arteries are used to determine the cerebral hemodynamic model associated with depression in men and women, respectively.

An agent for treating strokes in humans is tested in a non-human subject by selecting an agent for testing and by preparing a selected non-human subject. The preparation includes: inducing a stroke event by advancing a microwire through the arterial system of the subject to a selected intracranial target position, inserting a microcatheter along the microwire and delivering an embolic device to the target position, occluding the artery at the target position by deploying the embolic device, verifying the occlusion and repositioning the embolic device if needed. After a predetermined occlusion interval, reperfusion of the subject is simulated by removing the embolic device and commencing therapy with the selected agent. At appropriate intervals, the effect of the conducted course of therapy is assessed non-invasively until terminal evaluation. In particular aspects, the method involves occluding the middle cerebral artery through an access achieved via the basilar artery.

The invention discloses a traditional Chinese medicine preparation for treating chronic cervical vertigo. The traditional Chinese medicine considers that the cervical vertigo is caused by vertebral-basilar artery ischemia, and the pathogenesis of the cervical vertigo is blood stasis retardation of the brain network, unsmooth blood circulation, spleen weakness and deficiency of qi or interference of phlegm on the brain. Thus, traditional Chinese medicines including peach kernel, red sage root, artemisia anomala, corydalis tuber, trogopterus dung, milk vetch, bighead atractylodes rhizome, licorice, dried orange peel, nut grass and white tuckahoe with the functions of promoting blood circulation, eliminating stasis, strengthening the middle-jiao, invigorating qi, strengthening the spleen andreducing phlegm are selected to be prepared into a decoction for a patient to take, and the treatment effect is good. The clinical test in the hospital proves that the cure rate is 54.7%, the total effective rate is 96.9%, the cure rate and the total effective rate are higher than those of a western medicine control group, and the recurrence rate is low, thus the traditional Chinese medicine preparation disclosed by the invention is worthy of clinical popularization and application.

The invention discloses a traditional Chinese medicine composition for treating vertebral artery type cervical spondylopathy and a method for preparing the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 23-35 parts of the root of kudzu vine, 8-16 parts of rhizoma corydalis, 6-18 parts of cassia twig, 8-12 parts of rabdosia japonica, 4-8 parts of liquorice, 10-20 parts of caulis spatholobi, 6-10 parts of root or stem of Japanese Creeper, 10-14 parts of radix paeoniae rubra, 9-15 parts of white paeony root, 10-14 parts of burdock root, 7-13 parts of ramulus uncariae cum uncis, 8-12 parts of angelica sinensis, 9-11 parts of ligusticum wallichii, 6-14 parts of rhizoma gastrodiae, 5-15 parts of radix clematidis and 7-9 parts of polygonum runcinatum. The medicament has the excellent effects that the medicament has the efficacy of dispelling cold and wind, promoting blood circulation and removing blood stasis, and the like; the medicament can be used for effectively removing or relieving spasm of vertebral artery, and increasing elasticity of vessel walls, thus improving blood circulation of vertebro-basilar artery and eliminating symptoms; medicinal herbs resources are easily available, the cost of medicinal materials is low, and the burden of a patient can be reduced.

The invention provides an application of strictosamide in preparing medicaments for treating subarachnoid hemorrhage, which solves the problem that the medicaments for conventional treatment of subarachnoid hemorrhage are in shortage. The strictosamide has the following advantages and positive effects: strictosamide can markedly reduce the degree of encephaledema caused by subarachnoid hemorrhage, reduce the amount of residual blood in subarachnoid cavity, reduce the level of destruction of the blood brain barrier, reduce the degree of cerebral basilar artery vasospasm and increase the nerve function score. Through the improvement of the above clinical indicators, the prognoses of patients are improved, and the therapeutic action on subarachnoid hemorrhage is remarkable.

The invention discloses the application of furocoumarin compounds for preparing vasodilators. The dilating effect of furocoumarin compounds on the mesenteric second-class artery, brain basilar artery, renal artery and coronary artery in rats is investigated by in vitro microvascular tonography. The study result proves that the synthetic furocoumarin compounds can dilate the above four types of blood vessels to different extents and have a potential in vasodilator preparation.

A method for attenuating vasoconstriction in a patient with subarachnoid hemorrhage by administering to the patient a therapeutically effective amount of a compound which mediates an increase of bioactive nitric oxide in blood or tissue in the subarachnoid space to cause vasodilation in cerebral, carotid and basilar arteries after the administration of the compound, and wherein the administration of the compound does not reduce mean arterial blood pressure by more than 10%.

The invention relates to a specimen making method for a human cerebrovascular interventional operation, which comprises the following steps of selecting a human specimen and performing preservative treatment on the human specimen; selecting materials, wherein the head, the thorax and the abdomen are reserved, part of ribs and sternum are removed, upper limbs on the two sides are removed, and the middles of thighs are cut open; annularly sawing the top of the craniotomy, removing skin superficial fascia on the right side of the face, displaying parotid gland, removing skin superficial fascia onthe left side of the face, and exposing maxillary artery and branches; reserving partial skin and superficial fascia on the right side of the lower limb, removing the skin and superficial fascia on the left side, and displaying great saphenous veins, femoral arteries and branches; in the thoracic cavity: removing superficial fascia and deep fascia, and exposing heart appearance and head and arm stems; bleaching and washing the specimen; cleaning redundant tissues on the surface of the specimen; threading a guide wire, wherein in the right groin area, the guide wire is slowly inserted along the femoral artery till the common iliac artery, the internal carotid artery and the basilar artery are reached. And the prepared specimen has strong sense of reality, is beneficial to specimen observation, and is convenient for teaching and learning.

The invention discloses traditional Chinese medicine composition for treating PCIV (posterior circulation ischemia vertigo). The traditional Chinese medicine composition is prepared from raw materialsin parts by weight as follows: 15-25 parts of rhizoma gastrodiae, 15-25 parts of ramulus uncariae cum uncis, 8-12 parts of rhizoma ligustici, 10-15 parts of radix salviae miltiorrhizae, 10-15 parts of radix puerariae, 15-30 parts of caulis spatholobi, 5-10 parts of rhizoma sparganii, 1-3 parts of hirudo and 4-8 parts of lumbricus. According to the traditional Chinese medicine composition, clinical symptoms of a PCIV patient can be remarkably improved, the level of plasma fibrinogen, D-D dimer and blood viscosity is reduced, insufficient blood supply of vertebral-basilar artery of the patientis improved, D-D and FIB level of serum and arteriosclerosis index are reduced, the curative effect is obviously better than that of western medicine, and the traditional Chinese medicine compositiondoes not have obvious toxic or side effects. The invention further discloses a preparation method of the traditional Chinese medicine composition. The method is simple and easy, production and preparation are easy, and effective ingredients of medicinal components can be extracted to the greatest extent.

The invention relates to a Touqing prescription for treating cervical spondylosis, which is an oral medicine prescription made from pure natural plants such as fenugreek, lentils, magnolia officinalis, chuanxiong, angelica, gastrodia elata, kudzu root, rhubarb and licorice as raw materials through rational formulation. It combines the unique effects of various herbs, so that it has the effects of promoting clearness and reducing turbidity, aroma and stomach refreshing, promoting blood circulation and removing blood stasis. It is not only beneficial to relieve the clinical symptoms of patients, but also can improve local blood circulation, expand the vertebral basilar artery blood vessels, thereby improving the symptoms of vertebral basilar artery insufficiency in patients with cervical spondylosis. The clinical application is extensive, and it is safe and has no side effects, so it is an ideal drug prescription for treating cervical spondylosis.

The invention discloses a traditional Chinese medicine composition and application to treatment of vertebral artery type cervical spondylopathy.The traditional Chinese medicine composition is composed of, by weight, 10-80 parts of rhizoma gastrodiae, 10-50 parts of rhizoma chuanxiong, 10-80 parts of flos chrysanthemi, 10-50 parts of radix bupleuri, 10-60 parts of magnets, 10-60 parts of haematitum, 10-30 parts of herba menthae, 5-20 parts of herba asari, 10-40 parts of borneolum syntheticum, 10-50 parts of rhizoma ligustici, 10-50 parts of radix paeoniae alba, 10-50 parts of rhizoma et radix notopterygii and 10-30 parts of radix angelicae dahuricae and can be prepared into any commonly used dosage form.The medicine has the functions of dispersing cold and dispelling wind evil, activating blood and removing stasis and can remove or relieve carotid spasm and increase hemal wall elasticity, so that vertebra-basilar artery blood circulation is improved, and symptoms are removed.

The invention provides an application of strictosamide in preparing medicaments for treating subarachnoid hemorrhage, which solves the problem that the medicaments for conventional treatment of subarachnoid hemorrhage are in shortage. The strictosamide has the following advantages and positive effects: strictosamide can markedly reduce the degree of encephaledema caused by subarachnoid hemorrhage, reduce the amount of residual blood in subarachnoid cavity, reduce the level of destruction of the blood brain barrier, reduce the degree of cerebral basilar artery vasospasm and increase the nerve function score. Through the improvement of the above clinical indicators, the prognoses of patients are improved, and the therapeutic action on subarachnoid hemorrhage is remarkable.

The invention discloses a therapeutic rehabilitation instrument for adjusting blood flow velocities of an anterior artery, a median artery, a posterior artery, and a vertebra-basilar artery of a brain. The therapeutic rehabilitation instrument comprises a neck sleeve body; a pulse lead and a permanent magnet are installed on the neck sleeve body respectively; and the permanent magnet is connected with a pulse instrument by the pulse lead. According to the therapeutic rehabilitation instrument provided by the invention, the permanent magnet and the low-frequency electronic pulse unit are combined and are applied to a specific part of a human body surface and thus the blood flow velocities of the anterior artery, the median artery, the posterior artery, and the vertebra-basilar artery of the brain can be adjusted effectively and timely, so that normal blood supply can be improved or recovered and thus symptoms like dizziness or headache due to insufficient blood supply can be reduced or eliminated. Therefore, an objective of prevention can be achieved.

The invention relates to a medicine compound for treating aural vertigo and belongs to the field of medicine. The medicine compound is characterized by comprising the following materials: 150g of radix rehmanniae, 120g of radix achyranthis bidentatae, 120g of pulp of dogwood fruits, 150g of uncaria, 40g of lumbricus, 40g of antelope horns, 100g of ochre, 120g of nacre, 120g of ligusticum wallichii, 120g of rhizoma smilacis glabrae, 120g of rhizoma phragmitis, 80g of spina date seeds, 120g of angelica sinensis, 100g of radix ophiopogonis, 100g of cortex moutan, 80g of rhizoma alismatis, 80g of pinellia ternate, 80g of almonds, 50g of rheum officinale and 120g of liquorice. According to the invention, the traditional Chinese medicines are reasonably combined, and the combined traditional Chinese medicines are all common medicines, so that the treating cost is lower, the curative effect is relatively stable, and the medicine is conveniently taken and is free from obvious toxic or side effect. The medicine compound is especially effective in treating patients suffering from dizziness induced by Meniere's syndrome, labyrinthitis, vestibular neuritis, kinesia, insufficient blood supply of vertebra-basilar artery, neurasthenia, and the like.

The invention discloses a traditional Chinese medicine composition for treating cervical vertigo, and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from, by weight, 15-20 parts of rhizoma gastrodiae, 10-15 parts of uncaria, 5-10 parts of radix puerariae, 10-15 parts of rhizoma corydalis, 10-15 parts of rhizoma chuanxiong, 10-15 parts of radix angelicae dahuricae, 10-15 parts of radix scutellariae and 5-8 parts of radix glycyrrhizae preparata. On the basis of calming liver wind and promoting blood circulation to arrest pain, the traditional Chinese medicine composition has the effects of dredging channels and activating collaterals, clearing heat, reducing vagus nerve excitation, improving posterior cerebral artery, cervical vertebra basilar artery and vertebral artery posterior circulation and effectively improving dizziness and other symptoms of a patient, so that the effect of treating dizziness is achieved, and dizziness is mainly treated and is not prone to relapse after healing.

The invention relates to the technical field of image processing, in particular to an intracranial vessel bounding box automatic planning method and an intracranial vessel bounding box automatic planning device, wherein the method comprises the following steps that: the position of an interested blood vessel in the Willis circle is located on the basis of head CTA three-dimensional volume data, wherein the interested blood vessel is the middle cerebral artery, the anterior cerebral artery or the basilar artery; when the interested blood vessel is the middle cerebral artery, the direction of the artery is analyzed according to the position of the middle cerebral artery, and a corresponding Willis circle bounding box is planned by aiming at different observation directions; when the interested blood vessel is the anterior cerebral artery, the Willis circle bounding box in the observation direction from the front side to the back side is planned according to the position of the anterior cerebral artery; and when the interested blood vessel is the basilar artery, the Willis circle bounding box in the observation direction from the back side to the front side is planned according to the position of the basilar artery. The technical scheme can realize the automatic planning of the bounding box and has the advantages of high planning efficiency and high planning precision.

The present invention discloses a gastrodin injection, and at the same time also discloses a preparation method and a use thereof. The gastrodin injection comprises gastrodin, water for injection anda metal complexing agent. The gastrodin is subjected to water sedimentation, refrigeration, ultrafiltration and sterilization, ineffective ingredients are ensured to be completely removed, related substances in the preparation are reduced, the prepared preparation has good stability, the related substances and pyrogen items meet quality standards, a curative effect is stable, clarity is improved,and clinical experiments prove that gastrodin injection is capable of intravenous injection. The gastrodin injection is used for preparing drugs for treatments of neurasthenia, neurasthenia syndromesand traumatic brain syndromes, vertigo including Meniere's disease, drug vertigo, traumatic vertigo, sudden deafness, vestibular nerve cell inflammation, vertebral basilar artery insufficient blood supply, etc., neuralgia including trigeminal neuralgia, sciatica, occipital neuralgia, etc., and headache including vascular headache, migraine, neurasthenia, neurasthenia syndromes and other diseases.

The invention discloses a traditional Chinese medicine composition and application to treatment of vertebral artery type cervical spondylopathy.The traditional Chinese medicine composition is composed of, by weight, 10-80 parts of rhizoma gastrodiae, 10-50 parts of rhizoma chuanxiong, 10-80 parts of flos chrysanthemi, 10-50 parts of radix bupleuri, 10-60 parts of magnets, 10-60 parts of haematitum, 10-30 parts of herba menthae, 5-20 parts of herba asari, 10-40 parts of borneolum syntheticum, 10-50 parts of rhizoma ligustici, 10-50 parts of radix paeoniae alba, 10-50 parts of rhizoma et radix notopterygii and 10-30 parts of radix angelicae dahuricae and can be prepared into any commonly used dosage form.The medicine has the functions of dispersing cold and dispelling wind evil, activating blood and removing stasis and can remove or relieve carotid spasm and increase hemal wall elasticity, so that vertebra-basilar artery blood circulation is improved, and symptoms are removed.

The invention relates to an intraoral coil for high-resolution intracranial artery imaging. The intraoral coil comprises a handle, a flexible housing, a receiving coil unit, and a transmission device for transmitting the received magnetic resonance signal and / or data, the handle comprises a grip end and a connector, the handle is connected to the flexible housing through the connector, the grid end is a handheld portion for doctors to perform operation and positioning, the receiving coil unit is arranged on the flexible housing and comprises at least three sets of receiving coils, one end of the transmission device is connected with the receiving coils, and the other end of the transmission device is connected to an external receiving device. The intraoral coil is used for imaging head blood vessels via the oropharynx, especially the vertebral basilar artery, the unique oral ergonomic three-dimensional surface design is adopted, the intraoral coil can be easily put in the oral cavity of a patient easily and quickly, efficiency in examination is improved, the head blood vessel structure can be observed directly and clearly, and integrity and clearness in imaging are assured.

The invention discloses a blood flow simulation model of cerebral vessels under the simulated weightlessness condition, and belongs to the technical field of physiologic signal simulation. The model comprises an aorta canal, an brachiocephalic artery canal, a carotid canal, a subclavian artery canal, a vertebrarterial canal, an internal carotid canal, an external carotid artery canal, a basilar artery canal, an arteria cerebri media canal, an arteria cerebri anterior canal, a posterior cerebral artery canal, an anterior communicating artery canal and a posterior communicating artery canal, wherein the aorta canal, the brachiocephalic artery canal and the subclavian artery canal form a systemic circulation arterial rete; blood flows from the systemic circulation arterial rete to the carotidcanal and the vertebrarterial canal, then flows into a cerebral circulation arterial rete formed by the internal carotid canal, the external carotid artery canal, the basilar artery canal, the arteria cerebri media canal, the arteria cerebri anterior canal, the posterior cerebral artery canal, the anterior communicating artery canal and the posterior communicating artery canal; and the tail end of the cerebral circulation arterial rete is the downstream of the arteria cerebri media canal, the downstream of the arteria cerebri anterior canal, and the downstream of the posterior cerebral arterycanal. Through the adoption of the blood flow simulation model disclosed by the invention, the analysis of the interaction of the arterial blood flow of the systemic circulation and the cerebral circulation is deeper.

The invention discloses an application of Cystatin C in preparing a medicine composition used for treating cerebral vasospasm. Animal experiments prove that Cystatin C can induce high expression of autophagy on basilar artery walls, and has a controlling effect upon SD rat cerebral vasospasm after subarachnoid hemorrhage (SAH); and the effect has positive correlation with Cystatin C concentration. According to the invention, Cystatin C has substantial inhibiting effect against cerebral vasospasm after SAH, and can be used for ameliorating cerebral vasospasm after SAH.