16 results about "Headaches" patented technology

This invention discloses an environmental parameter sensing and adaptive adjustment system and method based on a photoconductive film. It integrates six-dimensional environmental sensors—light intensity, ultraviolet radiation, temperature, humidity, air pressure, and air quality—at the edge of the photoconductive film, and utilizes the film's directional light guidance and stray light filtering mechanisms to reduce environmental interference. The system includes an environmental sensing module, an environmental parameter processing module, a health data interface module, a correlation analysis module, an adaptive adjustment module, and an environmental early warning module. The correlation analysis module has preset environmental-health correlation patterns such as low temperature-increased blood pressure, high humidity-decreased blood oxygen, high ultraviolet radiation-skin health, poor air quality-respiratory diseases, and sudden changes in air pressure-headaches and joint pain, set based on clinical research data. The adaptive adjustment module pairs with smart home devices through a unified identity authentication center, sending control commands via Wi-Fi / Bluetooth / infrared to automatically adjust air conditioners, humidifiers, dehumidifiers, air purifiers, and lighting according to environmental parameters. The environmental early warning module supports single-indicator early warning, correlation early warning, trend early warning, and seasonal disease early warning, with customizable thresholds. The multi-environmental data fusion module uses weighted averaging and the 3σ principle for anomaly removal, integrating data from multiple devices such as mobile phones, watches, vehicles, and smart home devices. The sensors are automatically calibrated daily using meteorological bureau data, with the calibration process simultaneously linked to health data. This invention solves the problems of scattered environmental sensing devices, disconnect from health data, and inability to proactively adjust, serving as the infrastructure for intelligent health management.

This disclosure relates to heterocyclic compounds of Formula (I) as well as the preparation and use thereof. As contemplated herein, heterocyclic compounds of Formula (I) can be any one of a carbohydrate conjugate and an amino acid conjugate. The heterocyclic compounds of Formula (I) may be used for the treatment of neuropsychiatric, and neurodegenerative, neuroinflammatory and pain disorders including depression, as well as tobacco, opiate, and cocaine addiction, alcoholism, post-traumatic stress disorder (PTSD), and pain syndromes including cluster headaches and chemotherapy induced peripheral neuropathy.

The utility model discloses a wearable device for treating or preventing headache, which comprises a stimulator and a flexible fixing piece connected with the stimulator, and the flexible fixing piece can fix the stimulator on a wrist, a head or an upper arm; the first electrode is used for targeting wrist nerves on the wrist, and the stimulator is configured to provide electrical stimulation for the wrist nerves on the wrist through the first electrode; the second electrode is used for targeting frontal nerves of the head or sensory nerve C-type fibers on the upper arms, and the stimulator is configured to provide electrical stimulation for the frontal nerves of the head or the sensory nerve C-type fibers on the upper arms through the second electrode; the wearable device can be worn on the wrist, the head or the upper arm, so that a patient can freely select the wearing position according to the current use occasion and preference, the use requirements of the patient in various use scenarios can be met, the wearable device is convenient to carry daily, the use convenience of the headache treatment instrument is greatly improved, and more choices are provided for a user.

This article discloses a lipid prodrug of bromo-lysergic acid diethylamide (2-bromo-LSD) (2-bromo-lysergic acid diethylamide), which achieves improved pharmacokinetic properties and allows for easier long-term administration to patients. The disclosed lipid prodrug is indicated for the treatment of cluster headaches and mood disorders in human subjects.

This invention relates to the field of intelligent control technology for medical devices, and provides a device for monitoring and relieving headache abnormalities through stimulation intervention. The device includes a helmet-shaped main frame housing a monitoring and relief module; an intelligent control system that asynchronously collects physiological characteristics and hardware load status via a duplex channel, deriving a high-dimensional state fusion model; and a closed-loop evaluation and iteration module to establish a differential efficacy closed-loop mechanism, uploading the collected data to the cloud for storage, enabling historical data management, clinical analysis, and continuous optimization of personalized strategies. This technical solution addresses the problems of dependence and side effects associated with traditional drug treatments, the high trauma and cost of surgical treatments, and the tendency of existing migraine intervention devices to develop tolerance in the nervous system due to fixed and predictable stimulation parameters used in open-loop control, leading to gradual attenuation of intervention effects over time and an inability to provide personalized and precise treatment.

To provide a pharmaceutical product useful for the treatment or prevention of opioid δ receptor-related diseases. [Solution] The present invention relates to a pharmaceutical composition comprising a morphinan derivative that exerts opioid δ receptor agonist activity. By administering the pharmaceutical composition provided by the present invention, opioid δ receptor-related diseases (e.g., headaches) may be treated or prevented.

The invention relates to a therapeutic headband designed to relieve headaches, migraines, and tension through targeted pressure application. The headband applies pressure to acupressure points along the temples and the area in front of the ears, areas commonly associated with headache relief. The headband is worn comfortably around the head, with adjustable features that allow users to customize the pressure applied to each point.

The formulation of penile erecting gel comprises biosynthesized silver nanoparticles derived from Kaempferia parviflora extract containing 5,7-Dimethoxyflavone, in combination with sodium hyaluronate, isoprene glycol, phenoxyethanol, glycerin, propylene glycol, and ethylhexylglycerin. The manufacturing process involves blending the specified components, stirring to form a homogeneous gel, adding natural colorants and fragrances, and packaging in single-use plastic vials or aluminum foil sachets. This formulation represents an innovative application of nanotechnology in combination with Thai herbal medicine, enhancing localized vasodilation specifically at the penile region while minimizing systemic side effects such as headaches, nasal congestion, facial flushing, and blue-tinted vision associated with oral phosphodiesterase type 5 inhibitors (PDE5 inhibitors) like sildenafil (Viagra) or tadalafil (Cialis). Additionally, the gel exhibits antimicrobial and antioxidant properties.

Disclosed herein are methods of treating or preventing headaches (e.g., migraines) and / or photophobia in a subject comprising administering a pharmaceutical composition comprising one or more therapeutic agents selected from a triptan, a beta blocker, an alpha agonist, and a CORP antagonist.

A method of delivering a substance, such as one or more of a triptan, a nasal steroid or carbon dioxide gas, to the nasal cavity of a subject, in particular for the treatment of headaches, for example, migraine, or rhinosinusitis, for example, chronic rhinosinusitis, optionally with polyps, the method comprising the steps of fitting a nosepiece to one nostril of the subject, delivering the substance through the nosepiece to the posterior region of the nasal cavity of the subject.

An integrated medical platform with system and methods for enhancing medical procedures by rapid-data integration, artificial intelligence ("Al") analyses with real-time, data-driven insights generated by machine learning models, which are executed in real time and continuously evolving to assist medical professionals in providing favorable outcomes. Other aspects of the integrated medical platform are configured to improve quality of procedures, automate regulatory headaches and streamline clinical coordination to improve outcomes and cost. In some embodiments, a unified tracking system is configured to track TAVR procedures introduces hospitals to an integrated, multimodal Al-enabled platform designed as an all-in-one platform configured to improve planning and care coordination of complex procedures. Smart data collection optimizes billing and streamlines registry data capture. It provides predictive clinical guidance powered by privacy¬ preserving federated deep learning and generative Al improves patient care.

We provide the system. [Solution] A means of integrating biometric and environmental information collected from users, A means for predicting the occurrence of headaches using an artificial intelligence model based on the aforementioned integrated information, A means for generating a self-care method customized for the user based on the aforementioned prediction results, A system including means for notifying a user device of the aforementioned self-care method.

The invention discloses a ginseng and gastrodia elata orally disintegrating tablet and a preparation method and application thereof.The ginseng and gastrodia elata orally disintegrating tablet is prepared from, by mass, 5%-10% of crosslinked carboxymethyl gleditsia sinensis polysaccharide sodium and 90%-95% of fresh ginseng and gastrodia elata active freeze-dried powder, wherein the fresh ginseng and gastrodia elata active freeze-dried powder takes fresh ginseng and fresh gastrodia elata in a mass ratio of (1: 5)-(5: 1) as raw materials. According to the technical scheme, the ginseng and gastrodia elata orally disintegrating tablet can improve the utilization value of ginseng and gastrodia elata, is convenient to take or eat so as to meet the requirements of specific people, and can be used for relieving headache.

This invention belongs to the field of knowledge graphs and deep learning, and relates to a method for analyzing the causes of headaches based on knowledge graphs and deep learning. The method includes: acquiring unstructured text vectors representing the state of the analysis object and multidimensional temporal feature sequences; extracting multidimensional feature tensors after modal alignment; constructing a logical topology gating matrix based on a global knowledge graph and multiplying it with a dynamic edge feature matrix generated based on the overlap of time window integrals to obtain a path response intensity matrix; inputting this matrix into a graph neural network to perform topology pruning, blocking feature propagation paths that deviate from causal constraints. This invention maps ontology causal constraints to topology filtering criteria, restricting feature aggregation to the pathological logical manifold space, suppressing the excessive smoothing effect of graph convolution, and improving the accuracy of identifying subtle pathogenic factors.

Disclosed in the present invention are a cyclic amine compound with an aryl substitution, and a preparation method therefor, and a use thereof. The present invention provides the use of a substance Z or a pharmaceutical composition comprising the substance Z in the preparation of a serotonin 5-HT2A receptor agonist, the substance Z being a compound of formula I, a pharmaceutically acceptable salt thereof, a prodrug thereof, a solvate thereof, a deuterated derivative thereof, or a stereoisomer thereof. The pharmaceutical composition further comprises a pharmaceutically acceptable carrier. The compounds of the present invention can be used for preventing and treating depression, anxiety, cluster headaches, or neurodegenerative diseases.

Formulations of penile erection gel include biosynthetic silver nanoparticles derived from an extract of Kaempferia parviflora comprising 5, 7-dimethoxyflavone, as well as sodium hyaluronate, isoprene glycol, phenoxyethanol, glycerol, propylene glycol, and ethylhexylglycerol. The manufacturing process comprises the following steps: mixing the specified components, stirring to form uniform gel, adding the natural pigment and the essence, and filling into a disposable plastic small bottle or an aluminum foil small bag. The preparation is an innovative application of combining a nanotechnology and Thailand herbal medicines, can specifically enhance local vasodilatation in a penis area, and minimizes side effects of the whole body at the same time; such as headache, nasal obstruction, facial flushing, and hallucination of blue hue associated with oral administration of a type 5 phosphodiesterase inhibitor (PDE5 inhibitor), such as sildenafil (Viagra) or tadalafil (Heli). In addition, the gel also has antibacterial and antioxidant characteristics.