148 results about "Phenethylamines" patented technology

The invention discloses a fine circuit pattern anti-diffusion agent as well as a preparation method and a use method thereof, and relates to the technical field of printed circuit board manufacturing. The fine circuit pattern anti-diffusion agent is prepared from the following components in percentage by mass: 0.05 to 0.3 percent of an oleophobic agent, 0.1 to 0.6 percent of a bonding agent, 0.2 to 1.5 percent of an adhesion promoter, 0.5 to 4.0 percent of a wetting agent, 0.5 to 5.0 percent of a cosolvent and the balance of water, the oleophobic agent is a fluorophenylethylamine derivative, the bonding agent is a carbonyl chloride derivative, the adhesion promoter is a sulfur heterocyclic alkane derivative, the wetting agent is a methylsiloxane silane derivative, and the cosolvent is a sulfonyl ketone derivative. According to the fine circuit pattern anti-diffusion agent, an organic layer can be formed on the copper surface of a circuit board, the binding force between the copper surface and printing ink is enhanced, jet printing printing ink is prevented from diffusing on the copper surface, and the product percent of pass of a jet printing solder mask process is improved.

A composition of a compound represented by FIGS. 1A-1E for use in treating a medical disorder. A method of changing neurotransmission, by administering a pharmaceutically effective amount of composition to a mammal of a compound represented by FIGS. 1A-1E and inducing psychoactive effects in the mammal. A method of treating a patient having adverse reactions to psychedelics or entactogens, by administering a pharmaceutically effective amount of composition to the patient of a compound represented by FIGS. 1A-1E and avoiding adverse effects present with psychedelics or entactogens.

There are disclosed phenethylamine compounds, the use of such compounds in the treatment of diseases associated with a serotonin 5-HT2 receptor, pharmaceutical compositions such as tablet compositions and kits containing the compounds, methods of delivering the compounds in a mist via inhalation, and methods of treating diseases or disorders associated with a serotonin 5-HT2 receptor, such as central nervous system (CNS) disorders or psychological disorders with the disclosed compounds.

The invention relates to the field of composite materials, and particularly discloses a bio-based silica gel material and a preparation method thereof.The preparation method comprises the following steps that S1, an alkylated castor oil derivative is prepared, specifically, castor oil and maleic anhydride serve as raw materials to react to generate castor oil-based polycarboxylic acid ester containing double bonds, then mixing and reacting with an amino silane coupling agent to prepare an alkylated castor oil derivative; s2, mixing the alkylated castor oil derivative prepared in the step S1 with vinyl silane, 4-hydroxy-3-methoxyphenylethylamine, hermetia illucens oil, a catalyst and a pretreatment filler, and carrying out a reaction to prepare a silane group; s3, hydrolytic polycondensation: adding water into the silane group prepared in the step S2, hydrolyzing under an acidic condition to generate a colloidal silica, and drying to obtain a silica gel material; the invention further discloses the bio-based silica gel material prepared by adopting the preparation method. The bio-based silica gel material has the characteristic of preparing the bio-based silica gel material with higher mechanical property and heat resistance.

The invention discloses a composite membrane with adsorption separation and catalytic degradation functions as well as a preparation method and application of the composite membrane. The composite membrane is supported by a porous base membrane, a polyamide separation layer formed by reaction of a 3, 4-dihydroxyphenylethylamine and 2, 3-diaminophenol comonomer and acyl chloride is constructed on the surface of the porous base membrane through interfacial polymerization, and FeCo-g-C3N4 nanosheets are anchored in situ; the membrane can efficiently activate peroxymonosulfate (PMS) to generate free radicals under the nearly neutral condition, efficient interception and catalytic degradation of organic pollutants (such as antibiotics) are synchronously achieved, and heavy metal ions (such as Pb < 2 + > and Cd < 2 + >) are adsorbed through a functional monomer structure; the invention provides an interfacial polymerization preparation method of the membrane. The composite membrane breaks through the limitation of'only interception but not degradation 'of a traditional membrane, realizes integration of'separation-adsorption-degradation', can remarkably reduce the volume of concentrated water and reduce the toxicity of the concentrated water, and is suitable for advanced treatment of wastewater containing composite pollutants in the industries of pharmacy, printing and dyeing and the like.

The invention relates to a solid electrolyte of organic-inorganic hybrid halogen compound molecules, preparation thereof and an all-solid-state battery, and belongs to the technical field of energy storage batteries. The chemical general formula of the solid electrolyte is MaNb + eQcXdYa + bn + cq + dxZen or MaN2b + eQcXdYa + cq + dxZenObn, wherein M is selected from one of methylamine, ethylamine, propylamine, butylamine, aniline, benzylamine and phenylethylamine; n, Q and X are different metal elements; y is selected from halogen; z is a pseudohalide ion; the value range of a, b, c, d and e is 0 lt; a < = 3, 0lt; b < = 3, 0lt; c < = 1, 0lt; d < = 1, 0lt; e < = 6; and n, q and x are values of valences of the N element, the Q element and the X element respectively. The electrolyte material disclosed by the invention has high ionic conductivity, good flexibility and machinability and excellent air stability, and a battery formed by the solid electrolyte material has excellent electrochemical performance.

The invention belongs to the technical field of chiral material preparation, and particularly relates to a one-dimensional bismuth-based chiral perovskite crystal and a preparation method and application thereof. The general formula of the chiral perovskite crystal is (R-beta-MPA) 2BiI5 or (S-beta-MPA) 2BiI5, the chemical formula of the chiral perovskite crystal is C18H28BiI5N2, the R-beta-MPA represents (R)-(+)-beta-methyl phenylethylamine, the S-beta-MPA represents (S)-(-)-beta-methyl phenylethylamine, the R-beta-MPA represents (R)-(+)-beta-methyl phenylethylamine, and the S-beta-MPA represents (S)-(-)-beta-methyl phenylethylamine. The crystallographic data of the (R-beta-MPA) 2BiI5 include that the crystal belongs to an orthorhombic crystal system and a P212121 space group, and the cell parameters are as follows: alpha is equal to 90 degrees, beta is equal to 90 degrees, and gamma is equal to 90 degrees; the crystallographic data of the (S-beta-MPA) 2BiI5 comprises that the crystal belongs to an orthorhombic crystal system and a P212121 space group, and the cell parameters are as follows: alpha is equal to 90 degrees, beta is equal to 90 degrees, and gamma is equal to 90 degrees.

The invention provides a cracking method of a phenylethylamine compound, and relates to the technical field of organic chemistry. The cracking method provided by the invention comprises the following steps: in an oxygen-containing environment, a solvent environment and the participation of organic alkali, enabling a phenylethylamine compound to react at 20-40 DEG C for 2-5 hours, then breaking a carbon-nitrogen bond, and preparing a cracking product. According to the method, transition metal does not need to be used as a catalyst, meanwhile, cracking deprotection can be conducted on the phenylethylamine compound at the mild reaction temperature, the method is environmentally friendly, and the operation process is simple and safe.

The application discloses a clay stabilizer and a preparation method thereof, and belongs to the technical field of oil field additives, and comprises the following steps: dissolving a first monomer and 2,3-epoxypropyl trimethyl ammonium chloride in a solvent, or respectively dissolving the first monomer and 2,3-epoxypropyl trimethyl ammonium chloride in a solvent to configure a solution, then dropping the 2,3-epoxypropyl trimethyl ammonium chloride solution into the first monomer solution; then, reaction is carried out to obtain a reaction liquid; after the reaction is completed, the reaction liquid is separated and purified to obtain the clay stabilizer; the first monomer is an aromatic monobasic amine, the aromatic monobasic amine is one of aniline, p-aminotoluene and phenethylamine, the number of active hydrogens on an amine group in the first monomer is n, and the molar ratio of the first monomer to the 2,3-epoxypropyl trimethyl ammonium chloride is 1:0.9n-1.1n. The clay stabilizer has good shale inhibition effect, and the preparation method is simple and easy to popularize.

The invention relates to the technical field of medicines, and particularly discloses an application of 4-chloro-2, 5-dimethoxy-N-[(2-methoxyphenyl) methyl] phenylethylamine (25C-NBOMe) in preparation of a medicine for inhibiting addiction, and a preparation method of the 4-chloro-2, 5-dimethoxy-N-[(2-methoxyphenyl) methyl] phenylethylamine (25C-NBOMe). As a selective 5-HT2A receptor agonist, the compound can regulate a neural circuit from the prefrontal cortex to the marginal system and indirectly influence dopamine release, so that active drug foraging, relapse and preference behaviors of addicted individuals are inhibited. The invention further covers pharmaceutical salt forms and structural analogues of the compound and application of the compound in pharmaceutical compositions, and administration can be achieved through multiple dosage forms such as sustained-release implants and nasal spray. Compared with the existing drug for treating addiction, the invention has the advantages of independence, definite target spot, obvious curative effect, high safety and the like, is suitable for intervention of various addiction substances, and provides a new strategy for prevention and treatment of addiction behaviors.

The present application relates to a trace neodymium doped phenethylamine lead bromide monocrystal capable of simultaneously enhancing light yield and shortening decay time and application thereof, which solves the technical problem that the prior art is difficult to simultaneously improve light yield and shorten luminescence decay time. The trace neodymium doped phenethylamine lead bromide monocrystal capable of simultaneously enhancing light yield and shortening decay time is prepared by the following steps: 1) weighing; phenethylamine hydrobromide, lead bromide and neodymium bromide are weighed and placed in a glass bottle; the molar ratio of the phenethylamine hydrobromide, lead bromide and neodymium bromide is 2:1:(0.02-0.05); 2) obtaining a precursor solution; N,N-dimethylformamide is added to the glass bottle, heated and stirred until completely dissolved to obtain a precursor solution; 3) obtaining a crystal; the precursor solution is filtered and placed in a glass beaker for crystallization to obtain a neodymium doped phenethylamine lead bromide monocrystal; through adjustment of the crystal band structure by neodymium, the radiation recombination rate is improved.

The invention belongs to the technical field of medical polymer materials, and particularly relates to a preparation method of a surgical anti-adhesion hydrogel material. The material is prepared from 2, 3-diformylbenzoic acid modified gelatin, 3, 4-dihydroxyphenylethylamine, sodium hyaluronate, sodium tripolyphosphate, hydrogen peroxide, ascorbic acid and a phosphate buffer solution. Modified gelatin powder is obtained through a grafting reaction of 2, 3-diformylbenzoic acid and gelatin, then the modified gelatin powder, 3, 4-dihydroxyphenylethylamine and an auxiliary agent are prepared into a main gel solution, hydrogen peroxide and ascorbic acid are added before use, and the main gel solution is quickly crosslinked into gel under the body temperature condition. The obtained hydrogel can be stably combined with the tissue surface, the degradation process is matched with tissue repair, and the hydrogel has a free radical scavenging effect. Animal experiments show that the material can effectively reduce abnormal adhesion between postoperative tissues and has a good clinical application prospect.

The present invention relates to compounds according to formula (I), which are prodrugs of the psychoactive compound phenethylamine or its derivatives. The prodrugs provided herein exhibit improved pharmacokinetic properties during uptake as compared to phenethylamine (or the respective phenethylamine derivative), as well as reduced side effects resulting from the metabolites thus formed. Due to the affinity of the active phenethylamine compound, inter alia, for the 5-HT2a-receptor, these prodrugs are particularly advantageous for use in therapy, e.g., in the treatment of depression, posttraumatic stress disorder (PTSD), Alzheimer's disease or dementia.

The present invention discloses a novel aporphine compound, its preparation method and applications, and its structural formula is shown as follows. The name of the novel aporphine compound is 2-methoxy-9-hydroxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline (III 11 ). In the present invention: ① By using the computer-aided drug design method in the forefront field of pharmacy, this compound is designed according to the binding requirements of the drug action target; ② This compound is synthesized from 3-methoxyphenethylamine and 2-bromo-5-hydroxybenzaldehyde, and its preparation method is simple; ③ This compound is an aryl hydrocarbon receptor (AhR) agonist and an inducer for the generation of regulatory T cells (Treg cells), and can be used for the prevention and treatment of immune inflammation and related diseases. ④ This compound shows good plasma protein binding rate and bioavailability, and has good prospects for drug development. #imgabs0#

The invention belongs to the technical field of analytical chemistry, and particularly relates to a fluorescent probe for detecting phenylethylamine in an aqueous solution and urine and a detection method of the fluorescent probe, and the fluorescent probe for detecting phenylethylamine in the aqueous solution and urine is prepared from a cucurbit [8] uril aqueous solution and a coumarin derivative PDT aqueous solution; the coumarin derivative PDT is C20H21N2O3, the cucurbit [8] uril is C48H48N32O16, and the coumarin derivative PDT is C20H21N2O3. The fluorescent probe has remarkable advantages in the aspects of sensitivity, anti-interference performance, selectivity, quantitative detection capacity, low cost, simple and convenient preparation and the like.

The invention discloses a molecularly imprinted membrane of a new psychoactive substance and a preparation method and application of the molecularly imprinted membrane, the molecularly imprinted membrane comprises a membrane substrate and an adsorption material layer arranged on the membrane substrate, and the material of the adsorption material layer comprises 3, 3 ', 4', 4 '-tetramethyl-3, 3', 4 '-tetramethyl-3, 3'-tetramethyl-3, 3 '-tetramethyl-3, 3'- The molecularly imprinted polymer is prepared by using 2, 4-methylenedioxyphenylethylamine as an alternative template and using a bulk polymerization method. The novel molecularly imprinted membrane prepared by combining a molecularly imprinted technology and a separation technology is used as a membrane extraction material, and integrates the advantages of a membrane extraction technology and an imprinting technology, so that the problems that a membrane material is easy to pollute and low in selectivity are solved, and the novel molecularly imprinted membrane is suitable for being used as a membrane extraction material. The method shows the capability of accurately identifying a target analyte in the membrane separation process, has the advantages of high efficiency, stability, repeatability and the like, and provides a new technical means and potential application for identifying and detecting common forbidden drugs in a water body.

The present invention is directed to novel chemical compositions of matter, and in particular novel MDMA class of compounds having substituted methylenedioxyphenethylamine and substituted amphetamine, having a metabolically labile thioether group.

The invention relates to a body temperature-triggered adhesion degradable polyurethane patch as well as a preparation method and application thereof.The method comprises the steps that diisocyanate, semi-crystalline polyester diol, a carboxyl-containing chain extender and 3, 4, 5-trihydroxyphenylethylamine hydrochloride are taken as raw materials, and body temperature-triggered adhesion degradable polyurethane is synthesized through a condensation polymerization reaction; the degradable polyurethane is prepared into the degradable polyurethane adhesive patch capable of being triggered to be adhered by body temperature through a solution casting method. A polyester segment of the patch keeps high crystallinity at room temperature, a rigid physical cross-linked network is formed, molecular chain slippage and migration of catechol groups in 3, 4, 5-trihydroxyphenylethylamine hydrochloride are inhibited, and the patch does not show adhesion performance. At the body temperature, the crystalline region of the polyester segment is partially fused, the molecular chain segment obtains the movement ability to drive the suspended catechol group to migrate to the surface, the molecular thermal movement at the body temperature is intensified, the original hydrogen bond of the catechol is dissociated, and the catechol and the tissue surface form a hydrogen bond to realize adhesion. And stable and controllable degradation can be realized.

The invention relates to the technical field of organic synthesis, and provides a preparation method of 3-methoxy-4, 5-methylenedioxy phenylethylamine. According to the invention, myristic aldehyde and diethyl cyano phosphate are adopted as initial raw materials, and the 3-methoxy-4, 5-methylenedioxy phenylethylamine is prepared through wittig reaction, reduction reaction, hydrolysis reaction and Hofmann reaction. According to the preparation method provided by the invention, each step is simple and convenient to operate, the product yield is high (the total yield is 78.3%-84.2%), and the purity is high; furthermore, the preparation method provided by the invention is mild in reaction condition, does not need explosive and highly toxic chemicals, does not need column chromatography purification of products in each step, and is suitable for industrial production.

Disclosed herein are salts and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane, including salts, solid forms of the compound and salts thereof, as well as polymorphs of solid forms. The solid forms disclosed herein may have improved properties, such as improved physical, chemical, and / or pharmacokinetic properties. Also disclosed are methods for making the salts and solid forms and methods for administering the same. The disclosed salt and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane may be useful for treating neurological disease and / or a psychiatric disorder in a subject.

The invention discloses a growth method of an organic-inorganic hybrid two-dimensional phenylethylamine lead bromide perovskite single crystal, relates to a growth method of a phenylethylamine lead bromide perovskite single crystal, and aims to solve the technical problems of long growth period and small thickness of the existing two-dimensional phenylethylamine lead bromide single crystal. The method comprises the following steps: 1, obtaining seed crystals; 2, thermodynamically regulating and controlling the solution supersaturation degree by a constant-temperature water bath device; 3, seed crystal growth is dynamically regulated and controlled through a seed crystal rotating-gradient cooling method under the solution rotating condition, the phenylethylamine lead bromide perovskite single crystal is obtained, the length and width of the phenylethylamine lead bromide perovskite single crystal are larger than 2 cm, the thickness of the phenylethylamine lead bromide perovskite single crystal is larger than 2 mm, fast neutron detection and high-energy nuclear particle screening can be met, and the phenylethylamine lead bromide perovskite single crystal is applied to the field of nuclear radiation detectors.

The invention relates to a preparation method of cuprous oxide polycrystalline particles with a micro-nano structure, and belongs to the technical field of cuprous oxide polycrystal preparation, the preparation method comprises the following steps: firstly, dropwise adding an organic amine aqueous solution into a bivalent copper salt aqueous solution, stirring for reaction, then dropwise adding a reducing agent solution into a reaction solution, continuously stirring for reaction, and centrifuging and drying the reaction solution to obtain a product; the average particle size of the micro-nano structure cuprous oxide polycrystalline particles is 1-2.3 [mu] m, and the micro-nano structure cuprous oxide polycrystalline particles are formed by co-growth of small-size cuprous oxide crystals; the grain size of the small-size cuprous oxide crystal forming the cuprous oxide polycrystalline particle with the micro-nano structure is determined by the type of the organic amine, the organic amine is one or more of aniline, furfuryl amine, benzylamine, phenylethylamine and n-butylamine, and the grain size of the small-size cuprous oxide crystal is 40-600 nm. The crystal particle size of the polycrystalline particles formed by the method disclosed by the invention can be controllably adjusted in a range of 40-600nm by selecting different organic amines.

The utility model relates to a dissociation device for phenylethylamine salt compounds, which comprises a reaction kettle, the reaction kettle is connected with a dripping tank above the reaction kettle through a regulating valve, the reaction kettle is further connected with the dripping tank through a balance pipe, the reaction kettle is connected with an upper connector of a cross four-way connector, and the cross four-way connector is connected with a lower connector of the cross four-way connector. A lower connector of the cross-shaped four-way connector is connected with a centrifugal machine, a left connector of the cross-shaped four-way connector is connected with a nitrogen storage tank, a right connector of the cross-shaped four-way connector is connected with a diaphragm pump, and the diaphragm pump is further connected with a feeding port of a reaction kettle through a precision filter and a regulating valve in sequence; and regulating valves are arranged at four interfaces of the cross-shaped four-way joint. The dissociation device disclosed by the utility model can obviously improve the character of the dissociation crystal of the phenylethylamine salt compound, so that the crystal with uniform character is obtained, meanwhile, the cost and the working intensity are reduced, and the product quality and the yield are improved.

The invention relates to the technical field of medicine synthesis, and particularly provides a preparation method of Mavaktai. The method comprises the following steps: carrying out nucleophilic substitution reaction on barbituric acid and 2-chloropropane or 2-hydroxypropane to obtain 1-isopropyl barbituric acid; the preparation method comprises the following steps: reacting 1-isopropyl barbituric acid with a chlorination reagent to prepare 6-chloro-3-isopropyl pyrimidine-2, 4 (1H, 3H)-diketone; the preparation method comprises the following steps: carrying out nucleophilic substitution reaction on 6-chloro-3-isopropylpyrimidine-2, 4 (1H, 3H)-diketone and S-1-phenylethylamine under the condition of base catalysis, so as to prepare a crude product of the macavaktai. According to the method, the process operation is simplified, and the cost is reduced.

A process for producing a nitrogen-doped peony-shaped molybdenum oxide, comprising the following steps: (1) adding a regulator to a molybdenum-containing solution for reacting, concentrating and thermally treating to obtain a peony-shaped molybdenum oxide; and (2) dissolving the peony-shaped molybdenum oxide in a conditioning agent and adding an amine source for standing, centrifuging, washing, and heat-treating, thereby obtaining the nitrogen-doped peony-shaped molybdenum oxide; wherein the regulator is at least one of the following: nitric acid, ammonium nitrate, sodium persulfate, ammonium persulfate, concentrated sulfuric acid, H2O2, ozone, sodium hypochlorite, wherein in step (2), the conditioning agent is at least one of the following: sodium acetate, ammonium acetate, sodium formate, diaminoethane, sodium oxalate, ammonium benzoate, sodium phenylacetate, sodium propionate, sodium tartrate, sodium citrate, ammonium citrate; and wherein in step (2) the amine source is at least one of the following: aniline, dimethylamine, trimethylamine, benzylamine, phenethylamine, ethylamine, diethylamine, propylamine, phenylenediamine, xylylenediamine, amphetamine.

The present invention discloses a fine circuit graphic anti-diffusion agent and its preparation method and use method, relating to the field of printed circuit board manufacturing technology. The fine circuit graphic anti-diffusion agent is composed of the following mass percentage components: 0.05-0.3% oleophobic agent, 0.1-0.6% bonding agent, 0.2-1.5% adhesion promoter, 0.5-4.0% wetting agent, 0.5-5.0% cosolvent, and the balance is water; the oleophobic agent is a fluorophenylethylamine derivative, the bonding agent is a carbonyl chloride derivative, the adhesion promoter is a thiocycloalkane derivative, the wetting agent is a methylsiloxane-based silane derivative, and the cosolvent is a sulfonyl ketone derivative. The fine circuit graphic anti-diffusion agent of the present invention can form an organic layer on the copper surface of the circuit board, strengthen the bonding force between the copper surface and the ink, prevent the inkjet printing ink from spreading on the copper surface, and improve the product qualification rate of the inkjet printing solder mask process.

The present invention aims to provide a carbon dioxide absorbent that can efficiently absorb, fix, and simply separate and recover carbon dioxide in the air. The present invention relates to an atmospheric carbon dioxide absorbent consisting of an amine selected from the group consisting of m-xylylene diamine, benzylamine, phenethylamine, p-methoxybenzylamine, and p-trifluoromethylbenzylamine, and water, and having the amine content of 1 to 50 wt % with respect to the total amount. The present invention also relates to a method for generating carbon dioxide which uses the aforementioned carbon dioxide absorbent and is simple and superior in energy efficiency.

The application relates to the technical field of compound preparation, and discloses a synthesis method of fosfomycin intermediate levofosfoxacin salt, which comprises the following steps: taking propynol as raw material, performing esterification reaction, adding Pt / C, Cu (II) EDTA and hydrogen into the obtained reaction solution to prepare a cis-propenyl dichloro oxygen phosphorus solution, adjusting the pH of the reaction solution by using ammonia gas after hydrolysis, and performing salt reaction and epoxidation by using R- (+) -alpha-phenylethylamine to obtain the product after post-treatment. The propynol is not hydrolyzed after esterification, so that the impurity propadienyl phosphate is reduced; the later hydrogenation can obtain higher-purity cis-propenyl phosphate; the step of hydrolysis after esterification is reduced, a large amount of water does not need to be distilled and concentrated, and energy consumption is reduced; the reaction temperature and hydrogen pressure in the hydrogenation step are both low, and the reaction safety is high; R- (+) -alpha-phenylethylamine is used in the epoxidation stage, so that the splitting operation is not needed, and the process is simplified; the solvents can be recycled and reused, and the method is environment-friendly.

In one aspect, the invention provides a synthetic method of methyl ketone hydrochloride, and 3, 4-methylenedioxypropiophenone (MDP) is used as a starting material. In another aspect, the disclosure provides stereoisomers of methyl ketones. In another aspect, the present disclosure provides phenylethylamine or cathinone covalently bound to a chemical moiety in the form of a prodrug. The prodrug forms described herein allow for slow / sustained / controlled delivery of the parent phenylethylamine or cathinone into the blood system in a manner that increases the duration of therapeutic efficacy.

The invention discloses a DL-phenylethylamine resolution process, which belongs to the technical field of chemical engineering, and comprises the following steps: S1, resolution: heating D-glutamic acid and DL-phenylethylamine in a mixed solvent of methanol and water to react, then cooling to crystallize, filtering and drying to obtain a composite salt, S2, D-glutamic acid recovery: dissolving the composite salt obtained in the step 1 in water, and recovering the DL-glutamic acid to obtain the DL-phenylethylamine. And S3, dissociation: regulating the pH value of the mother liquor after the D-glutamic acid is recovered in the step 2 to 12 by using alkali, standing for layering, taking an upper oil layer, and distilling to obtain the S (-)-alpha-phenylethylamine. According to the present invention, the S-(-)-alpha-phenylethylamine is successfully efficiently prepared by using the D-glutamic acid as the resolving agent, the product yield is 81.8%, the optical rotation is-38.2 degrees, the optical purity is excellent, the resolving agent recovery rate is as high as 88.1%, the expensive catalyst or the complex equipment is not required, and the industrial implementation is easy.