149 results about "Joint pain" patented technology

A method for preparing nondenatured collagen type II for alleviating joint pain includes pulverizing a cartilage raw material and defatting to obtain a total protein crude extract; adding anhydrous ethanol to the total protein crude extract, soaking, stirring, and centrifuging to obtain an anhydrous ethanol insoluble material; dissolving the anhydrous ethanol insoluble material in water, adjusting pH to acidic, stirring and centrifuging to obtain an acid-insoluble material; dissolving the acid-insoluble material in water, performing enzymatic hydrolysis and centrifuging to obtain an enzymatic hydrolysis precipitate; dissolving the enzymatic hydrolysis precipitate in water, followed by performing co-fermentation, and centrifuging to obtain a fermentation precipitate; and adding a water activity regulator to the fermentation precipitate, and then drying to obtain the nondenatured collagen type II. The content of protein, hydroxyproline and nondenatured collagen type II in the prepared nondenatured collagen type II is high, and the shelf life is prolonged.

The invention belongs to the field of biological products, and particularly relates to a bone glue product for preventing and treating osteoporosis and application, the bone glue comprises sheep bone glue (small molecules), pig bone glue (small molecules) and black pig bone glue (small molecules); five animals are beneficial, sheep and pigs are food beneficial to body health, bones are made into bone glue (small molecules) through modern production processes such as an enzyme preparation method and the like, the bone glue (small molecules) is easily dissolved in water and easily absorbed by a human body, can supplement colloid in the bones, is non-toxic and can be eaten for a long time; due to different yin and yang attributes, different types of osteoporosis patients can be prevented and treated; the traditional Chinese medicine also has good prevention and treatment effects on complications, fracture, hairline fracture, arthralgia and other bone diseases caused by osteoporosis; the compound can be applied to preparation of medicines, foods and health-care foods for preventing and treating osteoporosis.

The invention belongs to the technical field of medical treatment, and discloses an osteoarthritis rehabilitation auxiliary device and system, and the device comprises an intelligent vibration treatment module, a pressure sensor and biological feedback module, an intelligent control and APP remote management module, a pressure sensor, an accelerometer, and a myoelectricity sensor. The joint pain is relieved, vibration can stimulate sensory nerves, pain signal transmission is reduced, and the pain degree is reduced. Vibration promotes secretion of joint fluid, friction is reduced, and the range of motion is improved. Low-frequency vibration stimulates the activity of cartilage cells, and cartilage degeneration is slowed down. And a biological feedback system is intelligently regulated and controlled, so that the treatment accuracy is improved. Non-invasive treatment is achieved, and no side effect exists; gastrointestinal discomfort caused by drug treatment or high cost of long-term physical treatment is avoided. Remote monitoring is achieved, compliance is improved, a patient can be treated at home and does not need to see a doctor frequently, and medical cost is reduced.

The invention provides a pharmaceutical composition for bone joints as well as a preparation method and application of the pharmaceutical composition. The pharmaceutical composition is prepared from the following components in parts by weight: 20 to 2000 parts of N-acetylglucosamine and 10 to 1000 parts of non-denatured type II collagen. In the compound composition of the N-acetylglucosamine and the non-denatured type II collagen, the two core components play a complementary role: the N-acetylglucosamine is focused on promoting synthesis of a cartilage matrix and provides a material basis for cartilage repair; the non-denatured type II collagen reduces damage of autoimmune response to cartilage through immunoregulation, the non-denatured type II collagen and the non-denatured type II collagen have a synergistic effect, the symptoms such as arthralgia and swelling can be relieved, the joint structure can be improved from the double angles of repairing and protecting, and particularly the treatment effect on patients with severe osteoarthritis is remarkably superior to that of a single-component preparation; and an innovative and efficient choice is provided for the treatment of osteoarticular diseases.

The present disclosure relates to amino acid and plant extract compositions and uses thereof, and also to joint care compositions comprising the amino acid and plant extract. The composition disclosed by the invention can increase bone hardness, prevent inflammatory response, relieve arthralgia and / or improve joint flexibility, so that systematic support is provided for bone and joint health.

This invention discloses a muscle-relaxing and meridian-clearing health powder and its preparation and application methods, belonging to the technical field of traditional Chinese medicine external health care products. The health powder is composed of fifteen raw medicinal materials: safflower, angelica, asarum, kudzu root, red peony root, scutellaria, dragon's blood, saposhnikovia root, frankincense, myrrh, cinnamon twig, mugwort leaf, coptis root, *Lycopodium clavatum*, and *Clematis armandii*. These materials are dried, pulverized to 80-120 mesh, and then evenly mixed. This invention, through a unique formulation design, integrates multiple effects such as promoting blood circulation and removing blood stasis, dispelling wind and cold, relieving muscle tension and clearing meridians, and clearing heat and drying dampness. Combined with a refined pulverization process, it significantly improves the dissolution rate and transdermal absorption efficiency of the drugs. During use, a hot compress applied via steam allows the medicinal properties to directly reach the affected area, effectively relieving pain and discomfort in the neck, shoulders, waist, legs, and joints. This invention's product has a scientific formulation, advanced technology, is convenient to use, and highly safe, possessing broad market application prospects.

The invention discloses a bone strengthening and pain relieving preparation and a preparation and use method thereof, and belongs to the technical field of traditional Chinese medicine. The preparation is prepared from unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, radix angelicae, radix cynanchi paniculati, ardisia crenata, radix salviae miltiorrhizae, cortex phellodendri, radix clematidis, peach kernels, flos carthami, cortex acanthopanacis, rhizoma drynariae, ground beetles, herba asari, short-pedicel aconite roots, borax and borneol. The auxiliary materials comprise sesame oil and minium. The prescription has the treatment rules and treatment methods of setting bones, relieving pain, clearing damp, dredging collaterals, diminishing swelling and dissipating blood stasis. The traditional Chinese medicine is mainly used for treating traumatic injury, soft tissue contusion and arthralgia, and belongs to qi stagnation and blood stasis type. The preparation is used by spreading the preparation on a non-woven fabric or oil paper. The plaster is heated and softened, and is pasted on an affected part. The traditional Chinese medicine has the symptoms of onset caused by trauma or strain, local swelling, stabbing pain, numbness of limbs, joint movement disadvantage or aggravated arthralgia when encountering wind-cold. The tongue is light, the tongue coating is thin white or white greasy, and the pulse is tight or soft.

The invention discloses application of a yang-warming and cold-dispelling traditional Chinese medicine composition in preparation of a medicine for improving cold limbs, and belongs to the field of traditional Chinese medicines. The prescription consists of folium artemisiae argyi, cassia twig, ligusticum wallichii, notopterygium root, divaricate saposhnikovia root, ginger, pepper, safflower, radix clematidis, radix aconiti carmichaeli, dried ginger and cinnamon according to a specific mass part ratio. The prescription disclosed by the invention has the effects of warming channels and expelling cold, and promoting blood circulation to remove meridian obstruction, and is mainly used for improving the symptoms such as cold hands and feet, intolerance of cold and sensation of chill, joint crymodynia and the like caused by insufficiency of yang qi and congealing cold in meridians. The invention also provides a preparation method of dosage forms such as an application agent of the prescription. Clinical tests show that the prescription preparation, especially the acupoint application agent, can obviously improve the symptoms, the total effective rate can reach 93.3%, the safety is good, and a safe, effective and convenient-to-use external treatment choice is provided for related diseases.

The utility model discloses a rheumatism immune arthralgia relieving device which comprises binding assemblies arranged up and down and supporting assemblies arranged in a bilateral symmetry mode. The upper end and the lower end of the supporting assembly are detachably connected with the corresponding binding assemblies respectively. The binding assembly comprises a left side plate and a right side plate, the left side plate and the right side plate are arc-shaped and have opposite concave surfaces, and a connecting structure is arranged between the left side plate and the right side plate; the supporting assembly sequentially comprises a hollow rod, an adjusting rod and an extension rod from top to bottom, a sliding connection structure is arranged between the hollow rod and the adjusting rod, and the adjusting rod and the extension rod are fixedly connected; installation structures are arranged between the hollow rod and the corresponding binding assembly and between the extension rod and the corresponding binding assembly. Hard fixation of the upper portion and the lower portion of the joint is achieved through the two arc-shaped plates, supporting performance is good, bone and meat at the joint are not prone to being dragged by slight movement, and pain during disease attack is relieved.

The invention discloses a joint health-care tablet based on glucosamine hydrochloride and sodium chondroitin sulfate and a preparation method, and relates to the technical field of medical health care. The joint health-care tablet comprises the following components: glucosamine hydrochloride, sodium chondroitin sulfate, a frankincense extract, an aesculus chinensis extract, microcrystalline cellulose, povidone, croscarmellose sodium and silicon dioxide. Through scientific proportioning of various active components such as the glucosamine hydrochloride, the chondroitin sulfate sodium, the frankincense extract and the aesculus chinensis extract, comprehensive protection of joint health is realized, the glucosamine hydrochloride and the chondroitin sulfate sodium are used as basic components, repair and regeneration of articular cartilage are promoted, and the joint health is improved. Boswellic acid compounds in the frankincense extract and aescin in the aesculus chinensis extract have anti-inflammatory and analgesic effects and can effectively relieve arthralgia and inflammation, multiple effects are synergistic, and the joint health care effect is improved.

The present invention demonstrates that isosakurabin can inhibit the formation and function of osteoclasts in vitro, protect the bone microstructure of the subchondral bone in mice with osteoarthritis (OA), reduce articular cartilage degeneration in OA mice, inhibit the formation of abnormal blood vessels in the subchondral bone marrow cavity during OA progression, and alleviate joint pain induced by abnormal osteoclast activation in OA mice. This invention demonstrates for the first time that isosakurabin has a therapeutic effect on osteoarthritis and reveals its mechanism of action.

The invention provides a tendon-relaxing, collateral-activating and pain-relieving breast plaster for shoulder, neck, lumbar vertebra, arthralgia and traumatic injury. The plaster is prepared from the following raw materials in parts by weight: 22-35 parts of frankincense, 41-55 parts of mirabilite, 26-40 parts of ligusticum wallichii, 31-40 parts of lycopodium clavatum, 5-20 parts of dragon's blood, 5-20 parts of pseudo-ginseng, 10-25 parts of radix clematidis, 40-55 parts of pawpaw, 35-45 parts of radix angelicae pubescentis, 40-50 parts of pericarpium zanthoxyli, 40-50 parts of ginger, 30-35 parts of rhizoma drynariae, 42-47 parts of radix aconiti kusnezoffii, 43-48 parts of radix aconiti, 45-50 parts of asarum, 40-50 parts of 20 to 30 parts of chamomile, 10 to 25 parts of menthol oil, 10 to 25 parts of camphor oil, 15 to 25 parts of lavender essential oil and 10 to 25 parts of wintergreen oil; 15-25 parts of radix saposhnikoviae oil, 15-25 parts of garden balsam stem oil and 15-30 parts of safflower oil. The ointment has special effects on shoulder, neck and lumbar vertebra, arthralgia, traumatic injury, tendon relaxing, collateral activating and pain relieving; and the traditional Chinese medicine composition has the effect of treating both symptoms and root causes without relapse and side effects.

The invention discloses qi-tonifying and bone-strengthening pills and a preparation method thereof, and belongs to the technical field of bone fracture pills. The qi-tonifying and bone-strengthening pill is prepared from the following raw materials: semen cuscutae, herba epimedii, cynomorium songaricum, salted radix dipsaci, scalded rhizoma drynariae, radix polygoni multiflori preparata, radix rehmanniae preparata, fructus lycii, wine-processed glossy privet fruit, herba ecliptae, raspberry, deer-horn glue, tortoise-shell glue, radix astragali preparata, radix angelicae sinensis, radix salviae miltiorrhizae, rhizoma dioscoreae, pericarpium citri reticulatae, fried semen ziziphi spinosae and radix glycyrrhizae preparata. The preparation method of the qi-tonifying and bone-strengthening pill comprises the following steps: adding water into the scalded rhizoma drynariae, and decocting; respectively crushing semen cuscutae, fried spina date seeds and dried orange peel; decocting the raw materials except deer-horn glue and tortoise-shell glue with the crushed semen cuscutae and fried spina date seeds in water, and concentrating the filtrate; and melting deer-horn glue and tortoise-shell glue in the concentrated liquid medicine, adding the crushed dried orange peel and a proper amount of refined honey, uniformly stirring, pelleting and drying to obtain the medicine. The qi-tonifying and bone-strengthening pill is mainly used for treating liver and kidney deficiency type arthralgia, poor rehabilitation in the later period of fracture and other symptoms, and has the functions of tonifying kidney and qi, and strengthening bones and promoting reunion of tendons.

The invention belongs to the technical field of plant essential oil, and discloses gaultheria yunnanensis composite essential oil and a preparation method thereof. The essential oil comprises the following raw materials: 40-60 parts of gaultheria yunnanensis essential oil, 10-20 parts of peppermint oil and 20-30 parts of ginger oil. The gaultheria yunnanensis essential oil is used as a core raw material and matched with the peppermint oil and the ginger oil, the effects of the gaultheria yunnanensis essential oil, the peppermint oil and the ginger oil are complementary, the anti-inflammatory and analgesic effects of the gaultheria yunnanensis essential oil, the cooling and itching-relieving effects of the peppermint oil and the effects of the ginger oil for promoting blood circulation to remove blood stasis and warming channels and expelling cold are mutually matched, and the problem The compound essential oil can comprehensively relieve various discomforts such as muscle and joint pain, swelling, mosquito bite itching and chilblain, the relieving effect is better than that of existing single essential oil or conventional compound essential oil, the effective components of methyl salicylate, menthol and gingerol of the three essential oils jointly act on pain and inflammation targets, and the relieving effect is improved.

The invention relates to the technical field of medicinal liquor, in particular to medicinal liquor and a preparation method thereof.The preparation method comprises the steps that main medicinal liquor raw materials are crushed, and medicinal powder is obtained; pouring the medicinal powder into Baijiu for mixed extraction, filtering after extraction, heating and concentrating, and cooling to obtain main medicinal liquor; preparing auxiliary medicinal liquor; and adding the auxiliary medicinal liquor into the main medicinal liquor to obtain the medicinal liquor. The premna microphylla is used as a main raw material and has the effects of diminishing inflammation, sterilizing, relieving pain, promoting blood circulation to remove blood stasis, removing necrotic tissue and promoting granulation, and the honeysuckle, the dandelion, the ganoderma lucidum and the like are used as auxiliary materials, so that the prepared main medicinal liquor is relatively good in overall functionality; in order to meet the treatment requirements of different kinds of diseases, different kinds of auxiliary medicinal liquor are compounded on the basis of the main medicinal liquor, part of diseases can be specifically treated, for example, gastrodia elata / polygonum multiflorum is used as an auxiliary material, and the obtained medicinal liquor has excellent performance in the aspect of treating arthralgia; corn cervi pantotrichum / ginseng / American ginseng are used as auxiliary materials, and the obtained medicinal liquor can better improve acne skin problems.

The invention belongs to the field of medical instruments, and particularly discloses a wearable hot compress device for relieving arthralgia, comprising: an internal medicine bag layer for contacting an arthralgia part; the middle wax therapy cladding is used for providing a stable and uniform hot compress environment; the external wearing layer is used for fixing the wearable hot compress device on an arthralgia part, and a rechargeable heating and temperature control device is arranged in the external wearing layer; the internal medicine bag layer is detachably connected with the middle wax therapy bag layer through a connecting part so as to be convenient to replace, and the middle wax therapy bag layer is medical paraffin wrapped by polyvinyl chloride. The external wearing layer provided with the charging type heating and temperature control device is used for heating, and the internal medicine bag layer is combined for wax therapy of medical paraffin, so that in the process of relieving pain, the effect of promoting local blood circulation through hot compress is achieved through the wax therapy; the medicine is matched and permeates to the affected part through the skin, so that the effect of reducing inflammatory factors is achieved, and the effect of fully relieving arthralgia at all positions is achieved.

The utility model provides an anti-direct-blowing structure of an air conditioner, which relates to the field of household equipment and comprises an air conditioner main unit, an anti-direct-blowing structure and a direct-blowing structure, the built-in plate is detachably arranged in the fixed screen frame; and the plurality of direct blowing prevention units are uniformly distributed on the built-in plate and are used for adjusting the airflow direction. By means of the spherical design and the universal rotation function of the air guide structure in the direct blowing prevention unit, airflow blown out of the air conditioner can be dispersed in a multi-angle and all-directional mode, cold air or hot air is effectively prevented from being directly blown to the human body, wind power can be dispersed, body discomfort such as cold and arthralgia caused by direct blowing is prevented, and the comfort level of indoor personnel is remarkably improved.

The present invention relates to the field of nutraceuticals, specifically to a synergistic bioactive composition designed to improve joint health. This composition comprises Palmitoylethanolamide (PEA) and Cucumis sativus, aimed at reducing joint pain and protecting cartilage. It addresses the complex pain components of osteoarthritis, including both nociceptive pain, which stems from ongoing joint inflammation and tissue damage, and neuropathic pain, which indicates nerve damage. This nutraceutical composition provides a novel solution for mitigating the debilitating effects of osteoarthritis through oral administration, utilizing pharmaceutically acceptable excipients to ensure efficacy and safety.

The preparation method comprises the following steps: taking simmondsia chinensis seed oil and sea buckthorn seed oil as substrates, compounding with traditional Chinese medicine components such as ganoderma atrum, salvia miltiorrhiza and the like, and treating by a nanocrystallization process. The essence oil is suitable for people with soreness of waist, cold abdomen and arthralgia, has the effects of dispelling wind, eliminating dampness and promoting blood circulation to remove blood stasis, has the permeability of 95% within 30 minutes, and is non-irritant.

The invention discloses a muscle-bone-joint pain rehabilitation therapy auxiliary device, and belongs to the technical field of rehabilitation therapy, the muscle-bone-joint pain rehabilitation therapy auxiliary device comprises a first rehabilitation mechanism, a second rehabilitation mechanism, a first binding mechanism, a second binding mechanism and an air pump, an elastic band is arranged between the first rehabilitation mechanism and the second rehabilitation mechanism, the elastic band is made of an elastic material, each of the first binding mechanism and the second binding mechanism comprises a binding belt, and a magic tape is arranged at the top of the binding belt of the first binding mechanism. Movable massage cold compress or hot compress is carried out on the muscle-bone-joint pain position of a user, the force applied to the muscle-bone-joint pain position of the user by the massage air bag becomes larger along with inflation of the massage air bag and becomes smaller along with deflation of the massage air bag, the muscle-bone-joint pain position of the user is fully massaged, and the rehabilitation effect is improved.

The invention discloses a rodent arthralgia threshold value measuring device and method, and relates to the field of pain sense measurement, the rodent arthralgia threshold value measuring device is characterized in that a pressure sensor is movably connected to a shell, and an automatic telescopic device is arranged in the shell; a pressure sensing probe is arranged on the pressure sensor; the automatic telescopic device is connected with the pressure sensor; the pressure sensor is connected with the display screen through a signal converter in the shell; a camera is arranged on the shell; the camera is connected with the display screen through a signal converter; the display screen is used for displaying a time-pressure change curve and animal behavior information; and based on the time-pressure change curve and the animal behavior information, taking the pressure value of the pressure sensing probe corresponding to the time point when the rodent has the effective withdrawal behavior as the pain threshold of the rodent joint, so that the requirement of simply, conveniently, quickly and continuously measuring the pain threshold is met, and the efficiency of measuring the pain threshold of the joint is improved.

A method of forming a suspension of an undenatured type II collagen is provided, wherein the method comprises the steps of: (a) combining a natural flavouring and / or preserve and water, and heating in a first heating stage; (b) adding a gum; (c) adding a hydrated pectin mixture, and heating to a temperature higher than the temperature of the first heating stage; (d) adding an undenatured type II collagen powder; and (e) cooling to form a suspension. The method may further comprise added an acidifying agent, such as citric acid, after adding the undenatured type II collagen. The gum may be selected from xanthan gum and / or lecithin sunflower gum. A suspension of an undenatured type II collagen prepared by the method is provided. An exemplary suspension for dogs comprises 40 wt% chicory root fibre, 4 wt% undenatured type II collagen, 1.2 wt% pectin, 0.55 wt% citric acid, 0.4 wt% xanthan gum, 0.3 wt% natural flavouring, 0.05 wt% potassium sorbate, and 53.5 wt% water. The suspension is preferably a gel that can be orally administered to a pet or animal with joint pain / arthritis.

The invention discloses a small-molecule chondroitin sulfate group effect compound for interventional treatment of joint inflammation and application, relates to the technical field of joint inflammation improvement, and aims to solve the problems that small-molecule chondroitin sulfate obtained by an existing single degradation method is single in action way and difficult to comprehensively cope with the complex pathological process of joint inflammation. The composition is composed of an oxidative degradation product LMCSO, an acid degradation product LMCSA and an alkali degradation product LMCSB according to the weight ratio of 6: 3: 1, the number-average molecular weight of the three products is smaller than 10 kDa, and the composition is prepared through specific oxidative degradation, acid degradation and microwave-assisted alkali degradation methods containing a phase transfer catalyst. The small-molecular chondroitin sulfate combined-effect compound can be used for preparing medicines beneficial to repairing bone joint injuries and relieving arthralgia or stiffness.

The present invention relates to an assembly having an EEG appliance, in particular a QEEG appliance and a head part, which has at least two applicators which generate a low-frequency electromagnetic field of an application frequency in a frequency range of 1 Hz to 100 Hz, preferably to 300 Hz, and having a field strength below 20 mT, for use in the treatment of dementia, depression, HRV regulation, Raynaud's syndrome, Asperger's syndrome, migraine, dizziness, sleep disorders, burnout, ADHD, muscular and / or joint pain, or autism.

This invention belongs to the field of rehabilitation training technology. It provides a method and system for analyzing upper limb rehabilitation training data, including the following steps: During the upper limb rehabilitation training process, static single-joint training parameter data and dynamic multi-joint collaborative training parameter data are collected in real time. The static single-joint training parameter data is then used to identify whether it meets the pain-free standard. This invention optimizes the problem of focusing only on single-joint data and ignoring multi-joint linkage and collaboration in upper limb rehabilitation training data analysis. It first identifies the static single-joint pain-free standard to eliminate basic interference, then filters and analyzes high-incidence combinations of multi-joint pain, and then reverse-engineers the final balance range where pain level meets the standard and range of motion is maximized, assessing the degree of achievement. Finally, it combines a safe expansion span to generate a stepped optimization range and predicts feasibility using a rehabilitation trend synergy index, achieving a shift from experience-driven to data-driven approaches.

To provide novel drugs effective in improving pain associated with osteoarthritis of the knee and periarthritis of the shoulder. [Solution] According to the present invention, a synovial pain reliever for arthritis is provided, comprising an endothelin A receptor antagonist as an active ingredient, wherein the arthritis is osteoarthritis of the knee or periarthritis of the shoulder. According to the present invention, it is possible to improve joint pain caused by movements that put a load on the knee joint and joint pain at rest in patients with osteoarthritis of the knee, and it is possible to improve joint pain caused by movements that put a load on the shoulder joint and joint pain at rest in patients with periarthritis of the shoulder.

To provide a wearable apparatus designed to address improper neuromuscular activation patterns that can result in asymmetrical biomechanical balance by providing a programmed neuromuscular resistance pattern to movement while the user performs certain repositioning or retraining exercises, which results in activating and inhibiting key muscle groups on the body. The apparatus also includes a bolster pad or structure that can be permanently or temporarily attached to the upper section of the apparatus underneath the thigh, which is crucial to be able to isolate the hamstring muscle during certain repositioning exercise by pushing down on the bolster while performing the exercise. After using the apparatus during repositioning and retraining exercises, the apparatus is removed and the user is more biomechanically balanced, thus allowing for an increase in the user's speed, strength and agility, and a decrease in any joint pain, during subsequent functional and sports activities.

Drug-loaded microspheres containing both a steroidal anti-inflammatory drug and a non-steroidal anti-inflammatory drug and injectable formulations containing the microspheres for sustained release of both drugs are disclosed. Methods of making such drug-loaded microspheres, formulations, and use of them for treating pains and inflammations, especially those caused by rheumatoid arthritis or osteoarthritis using such microspheres and formulations are also described.

The invention discloses a channel-warming, cold-dispelling and dampness-eliminating plaster for wind-cold-dampness arthralgia type osteoarthralgia and a preparation method thereof. The plaster is prepared by taking radix aconiti preparata and radix clematidis as monarch drugs, taking cassia twig, notopterygium root and radix angelicae pubescentis as ministerial drugs, taking frankincense, myrrh and safflower as adjuvant drugs and taking borneol and menthol as conductant drugs through scientific extraction and then combining with a water-based cataplasm matrix. Based on the theory of traditional Chinese medicine, the composition is precise and appropriate, the preparation process is stable, and the obtained product has the advantages of good transdermal absorption, remarkable curative effect, lasting effect, small skin irritation and the like, and is particularly suitable for symptoms such as arthralgia, swelling, unfavorable flexion and extension and the like caused by wind-cold damp evil.

The application discloses a traditional Chinese medicine micro-invasive regulating needle therapy method and belongs to the technical field of traditional Chinese medicine micro-invasive treatment, and solves the technical problems that traditional therapy for treating soft tissue pain only focuses on the local part and is difficult to solve the adhesion of deep and shallow fascia layers and has a high recurrence rate. The method takes a needle-knife as a main treatment tool, integrates a needle-knife medical theory, a fascia chain theory, a traditional Chinese medicine meridian theory and a biomechanics principle, adheres to a local relaxation + overall regulation core idea, accurately positions a treatment target through three points and one side, intervenes in inflammation-adhesion-spasm three pathological changes, follows a chain point finding and pain treatment by relaxation rule, and finally realizes a treatment goal of human body muscle and bone neutralization. The application is suitable for neck, lumbar vertebra disease, joint pain and related soft tissue lesions of head, face, spine and six big joints and has the advantages of micro-invasiveness, precision, treatment of both symptoms and root causes and low recurrence rate, and effectively restores the symmetry stability and functional coordination of the mechanical structure of the human body.