484 results about "Glucosamine Hydrochloride" patented technology

A topical skin rejuvenation preparation to relieve wrinkles, increase the skin's natural production of hyaluronic acid, reverse the lack of suppleness, hydrate from within, erase spider veins, reduce varicose veins, lighten aging dark blotches (“liver spots” / Lentigos, Senile Lentigines), decrease acne, and reduce under eye puffiness includes Glucosamine (2-amino-2-deoxy-alpha-D-glucose), a hexosamine (6 carbon amino sugar), including its derivative and precursor compounds: Glucosamine Sulfate, Glucosamine Hydrochloride, Glucose-6-Phosphate, Acetyl Glucosamine, Fructose-6-phosphate, Glucosamine-6-Phosphate, to increase production of Hyaluronic acid and collagen from Glucosamine Sulfate, its precursors and derivatives and to increase skin muscle tone by Dimethylaminoethanol (DMAE) while over coming deficiency it creates in each cell's production of PhosphatidylCholine, whose deficiency damages cell membranes, as well as mitochondrial and lysosome membranes.

An animal toy containing food having a first portion with food delivery means integrated therein adapted to securely house solid food treats, including a nutritional pet supplement, to be removed by the animal during play or through chewing action, and a second side with a plurality of gum stimulation teeth integrated within and projecting therefrom that act to massage the gums of the animal. Food delivery means may be provided as a plurality of cavities integrated within the first portion (and optionally, the second portion), preferably having a grooved or threaded interior for securely holding food pieces securely therein. Alternatively, the food delivery means is provided as a food portion composing the first portion. A pet supplement may be utilized, including joint preserving and joint rebuilding compositions comprising chicken collagen type II, glucosamine hydrochloride and chondroitin sulfate, a vitamin composition comprising vitamins C, D and K, a mineral composition comprising calcium, magnesium, zinc, copper, manganese and boron, a herbal anti-oxidant cofactor blend comprising citrus bioflavonoids, red grapes anthocyanins, turmeric rhizome, boswellia resin and fennel seed.

The patent relates to health foods containing natural astaxanthin, which is made into liquid capsule containing natural astaxanthin with natural astaxanthin oil, edible oil and fat and natural antioxidant as raw materials by conventional processing; or which is made into power capsule or tables containing natural astaxanthin with natural astaxanthin, natural antioxidant and other health food as raw materials by conventional processing. In comparison with present technology, the advantage of the invention includes, (1) the health food provided in present patent takes natural astaxanthin as main raw material, has the strongest antioxidant, capable of improving human immunity and anti-aging and ranking first in terms of health foods containing natural antioxidant; (2) the health food is made from pure natural materials and without any compound materials and side-effect; (3) the natural astaxanthin of health food coordinately used with shark cartilage, glucosamine hydrochloride, chitosan, propolis and paclitaxel etc as function material, which is capable of enhancing astaxanthin function; (4) adding antioxidant of natural tea-pigment and tea polyphenols is capable of avoiding oxidation of astaxanthin, thus prolonging shelf life more than one year.

The invention discloses a composition for reducing bone loss and a preparation method thereof. The composition is prepared from a calcium compound, marine fishbone collagen oligopeptide powder, glucosamine hydrochloride, casein phosphopeptides, natural vitamin E, vitamin C, vitamin K1, vitamin B12, vitamin D3 and dietary fiber. As proved by animal and human body tests, the composition has the effects of increasing bone density, enhancing bone intensity, reducing bone loss, delaying aging and enhancing the immunity, and can be taken by the middle-aged and old as a health-care food for a long time. The preparation method is scientific and reasonable, and is suitable for industrial production.

The invention discloses a high-efficiency multifunctional foliage fertilizer and a production method thereof. The foliage fertilizer is prepared by chelating shrimp processing leftovers, which serve as the main raw material, with medium and minor elements. The foliage fertilizer is prepared from 10-30% of amino acids, 2-8% of medium and minor elements, 10-30% of organic nitrogen, 3-20% of phosphorus, 3-20% of potassium, and 10-30% of shrimp peptide protein, chitosan, chitosan oligosaccharide, chitin, glucosamine hydrochloride, astacin and shrimp cephalin. The foliage fertilizer disclosed by the invention enhances the low-temperature tolerance, drought tolerance, salt damage tolerance, chemical damage tolerance and other stress tolerances of crops on the premise of comprehensively and efficiently supplementing necessary nutrients for crops, and has the functions of restoring the wound in the root system, enhancing the disease resistance of the crops, inhibiting disease and pest and the like. The production technique can reduce the acidolysis consumption, avoids introducing abundant inorganic salts and chloride ions to destroy soil ecological equilibrium and influence plant growth, lowers the energy consumption and requirements for equipment strength, and can implement the clean production of complete utilization and zero pollution discharge.

The invention relates to a composition with a function of increasing bone density and a preparation method thereof. Active components comprised by the composition are calcium carbonate, glucosamine hydrochloride, chondroitin sulfate, casein phosphopeptide, and soy isoflavone. The composition is prepared by reasonably and scientifically matching and combining the raw materials, and is prepared into oral preparations which are convenient to take. Experiments prove that the composition has the function of increasing the bone density.

The invention relates to a flower-shaped MoS<2>@graphene nanocomposite and a preparation method therefor. The nanocomposite is prepared by adopting a one-step hydrothermal synthesis method; graphene oxide, sodium molybdate and sulfourea are taken as the raw materials, and purified water is taken as the solvent; and then the flower-shaped and uniformly-loaded MoS<2>@graphene nanocomposite is obtained under the auxiliary effect of glucose or glucosamine hydrochloride. A TEM / SEM result proves that the ultra-thin MoS<2> nanosheets form the special flower shape, and are loaded to the high-quality graphene in a mono-dispersion manner; and an XRD spectrogram can prove that the MoS<2> is good in crystallization, and belongs to a hexagonal crystal system 2H-MoS<2> crystal phase. The graphene nanocomposite is simple in process, controllable in conditions, and high in load uniformity of the materials; and the prepared MoS<2>@graphene nanocomposite has a wide application prospect in the fields of new energies, such as the negative electrode material of lithium ion batteries, and the like.

The invention discloses a multicomponent traditional Chinese medicine containing composition for increasing bone mineral density and a preparation method thereof. The composition comprises the traditional Chinese medicine raw materials in parts by weight: 400-500 parts of herba epimedii, 400-500 parts of Rhizoma Drynariae, 300-400 parts of achyranthes root and also comprises the following nutritional substances in parts by weight: 75-95 parts of calcium carbonate, 40-60 parts of fish collagen powder, 20-38 parts of chondroitin sulfate, 5-6.2 parts of glucosamine hydrochloride, 10-13 parts of vitamin C and 0.0003-0.0004 parts of vitamin D. According to conventional process, an oral solid preparation is prepared by extracting herba epimedii, Rhizoma Drynariae and achyranthes root by ethanol and mixing the ethanol extract and the nutritional substances and appropriate amount of auxiliary materials. The medical composition provided by the invention has the function of increasing bone mineral density and can be used for prevention and assistant treatment of osteoporosis.

The invention relates to a Chinese medicine preparation, particularly a Chinese medicine preparation capable of increasing bone density and improving osteoporosis and arthralgia. The Chinese medicine preparation contains epimedium extract, radix salviae miltiorrhizae extract, D-glucosamine hydrochloride, biological calcium carbonate (oyster calcium), collagen hydrolysate, chondroitin sulfate and other active ingredients, wherein the D-glucosamine hydrochloride can obviously promote the proliferation and differentiation actions of the epimedium extract and radix salviae miltiorrhizae extract on osteoblasts. By combining the traditional Chinese medicine theory and the modern medicine research, the preparation tonifies the liver and kidney, strengthens the kidney and bone, promotes the bloodcirculation, dredges the collaterals and directly supplements calcium and collagen in a biological way, so that the kidney-qi is sufficient, and the bone is tonified, thereby improving ostealgia and arthralgia, enhancing the quality of life in the turn of life, and further performing the functions of increasing bone density and improving osteoporosis and arthralgia.

A topical composition for anti-aging treatment of the skin includes water soluble extract of Uncaria species, Arabidopsis thaliana extract, lipoic acid, dimethylethanolamine, tetrahexyldecyl ascorbate, dimethyl sulfoxide, Glycyrrhiza Glabra(Licorice) root extract, methylsulfonylmethane, phytosterols, D-ribose, tocotrienol, tocopherol, glucosamine hydrochloride, Pisum sativum extract; Bambusa vulgaris extract, and a dermatologically acceptable liposomal delivery medium. Further disclosed is a method using the topical composition for anti-aging skin treatment utilizing DNA repair in both the nucleus and the mitochondria. The topical composition can be applied on the skin of a person daily, and can also be applied in a dermal infusion treatment, with or without micro-dermal abrasion or skin suction. Topical application of the composition achieves effective reduction of pigmentation spots and degree of winkles, and improvement of skin color tone.

The invention discloses a preparation method of D-glucosamine sulfate sodium chloride salt. The preparation method comprises the following steps of: dissolving D-glucosamine hydrochloride in a solvent; adding a sodium-containing alkaline substance into the obtained solution at the temperature of minus 40-100 DEG C, or adding the sodium-containing alkaline substance into the obtained solution under the protection of one or more protective gas(s) of nitrogen, carbon dioxide and inert gases; adding the sodium-containing alkaline substance into the mixed solution at the maintained temperature of minus 40-90 DEG C; adding sulfuric acid into the obtained solution at the temperature of minus 25 to 90 DEG C for salifying; carrying out complexation reaction to obtain a D-glucosamine sulfate sodium chloride salt complex; and filtering and crystallizing to obtain the D-glucosamine sulfate sodium chloride salt solid. The method is novel and unique and simple and reasonable in technology, product quality is good and purity is high, and completely reaches the standard of United States patent (USP) 34 edition pharmacopeia.

The invention belongs to a natural product extraction method, in particular to a production technology separating glucosamine hydrochloride from citric acid sludge, which has the following steps: the citric acid sludge is sequentially hydrolyzed by hydrochloric acid, filtered, absorbed by resin, concentrated by vacuum, microfiltered, crystallized and centrifugated, and then is dried to obtain the glucosamine hydrochloride.

The invention relates to a BMD (bone mineral density)-increased health food composite and a preparation method of the BMD-increased health food composite. The BMD-increased health food composite comprises 180-220 parts by weight of red deer bone, 120-160 parts by weight of D-glucosamine hydrochloride, 80-100 parts by weight of chondroitin sulfate, 25-45 parts by weight of achyranthes root extractive, 20-40 parts by weight of drynaria rhizome extractive, 15-35 parts by weight of herba epimedii extractive, 10-20 parts by weight of casein phosphopeptides, and clinically-acceptable auxiliary materials, so that the hard capsule, the troche, the granule, the powder, the tea bag agent and the soft capsule can be prepared. According to the invention, a calcium source can be compensated by the red deer bone, the symptom of the osteoarthropathy can be improved by the D-glucosamine hydrochloride and the chondroitin sulfate, the calcium absorption can be promoted by the casein phosphopeptides, and the functions of nourishing the liver and kidney and strengthening the bones and muscles can be achieved due to the compatibility of traditional Chinese medicines. The BMD can be effectively increased due to the joint compatibility of the raw materials; a finished product is simple in preparation technology; and the health food provided by the invention is exact in effects, safe, and free of toxic and side effects, and can be taken for a long term, so that the general flavone in every 100g in the content of effect ingredients of the health food composite is higher than 0.5g.

The invention relates to a medicinal composition for treating osteoporosis and a preparation method thereof. With increasingly clear trend of China's aging population, osteoporosis becomes a common disease and a frequently encountered disease among the middle-aged and old people, and the traditional treatment has high treatment cost and has no quite ideal treatment effect. The invention provides the medicinal composition for treating the osteoporosis and the preparation method thereof, wherein the medicinal composition comprises the following raw materials in part by weight: 140 to 180 parts of D-glucosamine hydrochloride, 80 to 120 parts of calcium carbonate, 0.0008 to 0.0012 part of vitamin, 40 to 80 parts of chondroitin sulfate, 40 to 80 parts of starch, 10 to 30 parts of dextrin and 2 to 4 parts of magnesium stearate. The vitamin D added into the composition regulates the bone metabolic hormone, and ensures stable internal environment of bone and calcium; the predominant crushing and mixing conditions can improve the absorption of calcium and other active ingredients, and the mixing mode is more scientific; after the starch is selected and ground and the surface is saturated, the vitamin D is added, so the bioactivity of the vitamin D is ensured; and after the tabletting is finished, a coating is coated on the vitamin so that the vitamin D is more stable.

The invention discloses a medicinal composition with a function of increasing bone density. The medicinal composition is an oral preparation which is prepared from the following active ingredients in percentage by weight: 10-40 percent of calcium carbonate, 5-30 percent of D-Glucosamine hydrochloride, 5-20 percent of chondroitin sulfate, 5-30 percent of epimedium extract, 3-10 percent of achyranthes bidentata extract and 3-15 percent of casein phosphopeptides. The medicinal composition is a Chinese medicinal preparation which contains no toxic medicinal crop, and has the characteristics of effect of increasing the bone intensity, obvious curative effect, low manufacturing cost, high curative effect, quick response and no toxic or side effect.

The present invention provides a medicine composition with analgesic and anti-inflammatory functions, which belongs to medicine technology field. The medicine composition contains 1-25 parts extract of curcuma, 1-25 parts glucosamine hydrochloride, 1-10 parts beta-sitosterol. The medicine also can add other nutrition compositions such as vitamin C, vitamin E, vitamin K, chondroitin sulfate, vitamin A, vitamin D, immunoglobulin etc. The medicine is processed to various oral agent with acceptable carrier or excipient as substrate in medicine by conventional process. It was verified by animal experiment that the medicine has functions of analgesic and anti-inflammatory, and can be used to prepare medicine and food for preventing chest rib twinging, dysmenorrhea, shoulder and arm pain, injuries from impacts, gout, rheumatoid arthritis etc.

The invention discloses a prescription with function for mitigating and curing osteoarthrosis, which comprises the components by weight percent: 3.3-66.7% of glucosamine hydrochloride, 10.67-16% of chondroitin sulfuric acid, 4-9.33% of soybean extract, 2.67-5.33% of pseudo-ginseng extract, 4-13.33% of drynaria rhizome extract, 1.33-4% of antioxygen, 1-3% of lubricating agent A and 0.267-0.533% of lubricating agent B. The preparation method of the prescription comprises the steps of: jointly mixing, filling capsule, polishing, detecting semi-manufactured goods and packing into capsule dosage. With the clinical observation of Shanghai No.6 People's Hospital, the prescription has high ramollescence for osteophyte or bony spur, has various coordinated effects of analgesia, anti-inflammation, detumescence and microcirculation improvement, and the like, and has effective rate of 86.67% for curing osteoarthrosis.

The invention provides a stable, efficient and low-cost inactivated lactic acid bacterium liquid preparation to solve the technical problems that existing inactivated lactic acid bacterium preparations are high in cost, and the effective element recovering rate is low. The acid additives such as Betaine hydrochloride, glucosamine hydrochloride and gamma-aminobutyric acid are used as inactivators, the cost of the inactivation method is far lower than that of other inactivation methods, and the liquid preparation is far better than thermal inactivated lactic acid bacterium preparations on the aspects of the biological activity such as the cell recovering rate, the adhering performance to cancer cells of human body and promoting of the growth of animals; the production cost is greatly reduced, and the cost performance of the inactivated lactic acid bacterium liquid preparation is improved.

The invention relates to a pharmaceutical composition for the treatment of osteoarthritis, the composition of the invention consists of 5 to 10 weight parts of glucosamine hydrochloride, 5 to 10 weight parts of sodium chondroitin sulfate and 1 to 4 weight parts of sodium hyaluronate, and the needed oral formulation can be prepared by adopting the conventional preparation technology along with acceptable excipients in pharmacy. The pharmaceutical composition of the invention has the functions of prevention and treatment of osteoarthritis, so the invention can be used in the preparation of the drugs for the prevention and treatment of osteoarthritis and can also be used as the health care food which has the function of prevention of osteoarthritis.

The invention discloses a medicine composition for treating osteoporosis and a preparation method thereof. The medicine composition is prepared from collagen, chondroitin sulfate sodium salt, calcium carbonate, rhizoma drynariae extract, kudzu vine root extract, D-glucosamine hydrochloride and pseudo-ginseng. The medicine composition can be used for treating the pathogenesis, namely destruction of bone microstructure, of osteoporosis, is capable of solving the problem of bone density abnormality and radically preventing and treating osteoporosis; and the medicine composition can be used for relieving symptoms of ostealgia of osteoporosis patients, healing of bone fracture can be promoted, and the living quality of osteoporosis patients can be improved.

The invention discloses a compound preparation used for joint care and a preparation method thereof. The compound preparation comprises active ingredients and auxiliary materials, wherein the active ingredients comprise glucosamine, chondroitin sulfate, dimethyl sulfone and collagen, and the glucosamine is glucosamine sulfate or glucosamine hydrochloride or glucosamine phosphate or mixture of theglucosamine sulfate and the glucosamine hydrochloride and the glucosamine phosphate; and the auxiliary materials comprise excipient, disintegrant, lubricant, bonding agent and wetting agent. The invention has better treatment and prevention functions on arthritis and joint injury; the prepared tablet has good disintegration property, rapid digestion, quick effect taking, strengthened stability andhigh absorption and utilization ratio; and the consumption of the raw materials and the auxiliary materials achieves the optimal proportion.

The invention discloses a method for preparing a nitrogenous porous carbon material for an electrode material of a super-capacitor, which belongs to the field of electrochemistry and new energy materials. The method comprises the following steps of: using amino-glucose hydrochloride or amino-glucose sulfate as a raw material; preparing a nitrogenous porous carbon precursor by using a hydro-thermal method; mixing the precursor with potassium hydroxide; and realizing one-step carbonization and activation under the protection of an inert gas. The prepared nitrogenous porous carbon material has an appropriate specific area, and appropriate nitrogen content, the specific capacitance of the nitrogenous porous carbon material in aqueous electrolyte can be up to 270 F / g, the specific capacity of the nitrogenous porous carbon material in an organic system can be 160 F / g, and the nitrogenous porous carbon material is an ideal electrode material of the super-capacitor.

The invention discloses a preparation method for preparation containing glucosamine and an application thereof. The preparation is characterized in that the major component is one or the combination of more of the glucosamine, glucosamine hydrochloride, glucosamine sulfate sodium chloride double salt or potassium chloride double salt, and chondroitin sulfate. The preparation method is simple, convenient and time-saving to operate and is easy for large industrialized production.

The invention discloses a glucosamine chewable tablet used for relieving and preventing osteoarthritis and a preparation method thereof. The glucosamine chewable tablet comprises active ingredients and auxiliary materials, wherein the active ingredients comprise glucosamine, vitamin C and dimethyl sulfone, the glucosamine is glucosamine sulfate or glucosamine hydrochloride or glucosamine phosphateor mixture of the glucosamine sulfate and the glucosamine hydrochloride and the glucosamine phosphate; and the auxiliary materials comprise excipient, bonding agent, flavouring agent and lubricant. The glucosamine chewable table is slowly disintegrated and released without entering the gastrointestinal tract through the chewing and is absorbed through the increment of the taking number, therefore, the medicine effect is improved, and the discomfort of a patient with poor gastrointestinal tract function, caused by a deglutible tablet accelerating the gastrointestine load, is reduced. The glucosamine chewable tablet has the advantages of good mouth feel, high bioavailability, more convenient taking, convenient carrying and the like, and can fully play a role of the product.

The invention relates to a composition for increasing the bone mineral density and preparation and a preparation method thereof. The composition is mainly prepared from, by weight of parts, calcium carbonate, D-glucosamine hydrochloride, chondroitin sulfate, collagen protein, a casein phosphopepetides, a davallia mariesii extract and a vitamin K2. On the specific matched condition, the effect of remarkable synergistic interaction for treating osteoporosis is achieved, and the effects of blocking calcium loss and reinforcing calcium absorption are achieved; after traditional Chinese medicines of shaddock peels, chicken shells, purple bergenia herb and schisandra chinensis are added, the effect of increasing the bone density is further enhanced, and meanwhile the effects of treating the joint inflammation, tonifying the spleen and the kidney, strengthening tendons and bones, improving immunity and the like are achieved.

The invention relates to a bone mineral density increase health capsule and a preparation method thereof. The capsule is composed of a capsule body and a content closed in the capsule body. The content is characterized in that the content comprises 15-30wt% of calcium carbonate, 8-20wt% of chondroitin sulfate, 10-25wt% of D-glucosamine hydrochloride, 0.02-0.2wt% of vitamin K1, 10-20wt% of a collagen polypeptide, 5-15wt% of momordica saponin, 5-15wt% of soybean isoflavone, 5-20wt% of sheep bone marrow peptide powder, 0.1-0.5wt% of vitamin D3 and 0.5-1wt% of an auxiliary material magnesium stearate; and the preparation method comprises the following steps: uniformly stirring the content, sending the uniformly stirred content to a capsule filling machine for filling the content to capsule shells, polishing, choosing, and packaging to obtain the bone mineral density increase health capsule. The health capsule has the advantages of synergistic effect of the above components, common improvement of the absorption of calcium by human bodies, bone mineral density increase, safety, reliability, obvious effect, and carrying and administrating convenience. The preparation method of the health capsule has the advantages of reasonable technology and strong operability.

The invention provides a new method that prepares glucosamine hydrochloride by adopting chitosan, which comprises the steps of the hydrolysis of hydrochloric acid, the cooling crystallization of mother liquid, the concentration of filter liquid, the cooling crystallization of concentrated solution, decolorization, the crystallization of decolorized liquid, fining, etc. The preparation method of the invention adopts the cooling crystallization firstly after the hydrolysis and the concentration of filter liquid to cause the glucosamine hydrochloride to be separated from the liquid that contains relatively high impurity content and also cause grease and impurities to be separated and suspended at the top layer of crystalline solids, thus being beneficial for removing the grease and the impurities. The preparation method of the invention can obtain the glucosamine hydrochloride with high purity and high yield in the condition that hydrochloric acid concentration is 30-32 percent and reaction temperature is 85-88 DEG C and greatly reduces the dosage of activated carbon, thus greatly saving manufacturing cost.

A topical composition for anti-aging treatment of the skin includes water soluble extract of Uncaria species, Arabidopsis thaliana extract, lipoic acid, dimethylethanolamine, tetrahexyldecyl ascorbate, dimethyl sulfoxide, Glycyrrhiza Glabra(Licorice) root extract, methylsulfonylmethane, phytosterols, D-ribose, tocotrienol, tocopherol, glucosamine hydrochloride, Pisum sativum extract; Bambusa vulgaris extract, and a dermatologically acceptable liposomal delivery medium. Further disclosed is a method using the topical composition for anti-aging skin treatment utilizing DNA repair in both the nucleus and the mitochondria. The topical composition can be applied on the skin of a person daily, and can also be applied in a dermal infusion treatment, with or without micro-dermal abrasion or skin suction. Topical application of the composition achieves effective reduction of pigmentation spots and degree of winkles, and improvement of skin color tone.

The invention is an ingestible wellness one time daily dosage made of a large quantity of rapid absorbing glucosamine sulfate, glucosamine hydrochloride, and an n-acetyl glucosamine and combinations thereof, a large quantity of chondroitin sulfate, chondroitin hydrochloride and combinations thereof, a vasodialating sulfonate with at least one methyl group, and a buffer to reduce adverse symptoms from large amounts of glucosamine and chondroitin selected from the family of araliaceae and a B3 vitamin, wherein the invention is also a wellness beverage that involves a fluid combined with the ingestible wellness dosage.

The invention provides a traditional Chinese medical health-care preparation for increasing bone density. The traditional Chinese medical health-care preparation comprises the components in parts by weight as follows: 180-310 parts of bovine-derived power, 330-460 parts of herba epimedii, 240-340 parts of dodder, 200-300 parts of glossy privet fruit, 500-700 parts of the fruit of Chinese wolfberry, 180-260 parts of ginseng and 70-120 parts of glucosamine hydrochloride. Based on bovine-derived power, dodder, the fruit of Chinese wolfberry and glossy privet fruit as main raw materials, the raw materials of the preparation proved by modern researches have the function of increasing the bone density, and are matched with appropriate assistant materials to prepare health-care food, so as to improve and relieve osteoporosis and feat fracture caused by decrease of bone density by increasing the bone density. The product verified by toxicological evaluation of health-care food safety is safe and nontoxic, and can be taken for a long time; the product verified by animal function test has the function of increasing the bone density; and the product verified by hygienic, stability and functional component examination is stable and controllable in quality.