725 results about "Bone density" patented technology

A surgical apparatus, system and methodology are provided that may be utilized to treat a plurality of medical conditions. A robotic apparatus may be utilized in the treatment of a medical condition or to assist a medical professional in a surgical procedure. Additionally, the robotic apparatus and system may be utilized during a surgical procedure to provide guidance and to narrow the margin of error. In an exemplary embodiment, a scan may first be performed on a patient to determine a plurality of surgically necessary characteristics, such as bone density, locations, and the like. A virtual treatment plan may be provided by the system. An active and / or passive robotic apparatus may be provided to assist in the surgical technique. The robotic apparatus may be an active robotic which includes surgical tools whereby the medical professional may perform the surgical technique with the assistance of the active robotic apparatus.

A dual energy scanning densitometry system for imaging and measuring bone density maintains acceptable flux by adjusting the x-ray current or scan speed according to preceding scan line data. The amount of acceptable flux is maintained within limits modified by information about the region of the body being scanned so that different precisions may be maintained for different body regions. Scan speed and current may be controlled so that scan speed is maximized within the current limits. Essentially continuous flux control can be achieved.

A method for the in vivo non-invasive characterization of the material and architectural properties of a bone in which an ultrasonic wave is introduced into a bone in such way as to produce one or more guided wave modes within the bone, and the signals emerging from the bone are stored and analyzed to determine the propagation characteristics of the guided wave / s. These measured guided wave propagation characteristics are then processed to obtain estimates of desired bone properties such as cortical thickness, bone density and bone elastic constants. The invention also includes an unltrasound arrangement with movable transducers.

The invention is directed to a method of inhibiting bone resorption. The method comprises administering to a human an amount of sclerostin inhibitor that reduces a bone resorption marker level for at least 2 weeks. The invention also provides a method of monitoring anti-sclerostin therapy comprising measuring one or more bone resorption marker levels, administering a sclerostin binding agent, then measuring the bone resorption marker levels. Also provided is a method of increasing bone mineral density; a method of ameliorating the effects of an osteoclast-related disorder; a method of treating a bone-related disorder by maintaining bone density; and a method of treating a bone-related disorder in a human suffering from or at risk of hypocalcemia or hypercalcemia, a human in which treatment with a parathyroid hormone or analog thereof is contraindicated, or a human in which treatment with a bisphosphonate is contraindicated.

A method for the in vivo non-invasive characterization of the material and architectural properties of a bone in which an ultrasonic wave is introduced into a bone in such way as to produce one or more guided wave modes within the bone, and the signals emerging from the bone are stored and analyzed to determine the propagation characteristics of the guided wave / s. These measured guided wave propagation characteristics are then processed to obtain estimates of desired bone properties such as cortical thickness, bone density and bone elastic constants. The invention also includes an unltrasound arrangement with movable transducers.

A combination of an anti-androgenic gestagen at a daily dose of from an ovulation-inhibiting dose up to at most twice the ovulation-inhibiting dose and from 0.1 to 10 mg of (6S)-5-methyltetrahydrofolate are used to produce a pharmaceutical preparation for therapeutically treating endometriosis while simultaneously reducing therapy side effects including the negative effect on bone density and / or bone metabolism, reducing the risk of osteoporosis and, in the event of pregnancy, reducing the risk of congenital malformations, such as medullary tube defects, cleft lip, cleft jaw, or cleft palate, and the risk of pregnancy complications, such as detachment of the placenta and premature birth. The preparation is suitable for long-term administration, which continues daily for at least 169 days to at least two years.

The pharmaceutical preparation for treating endometriosis contains at least 28, preferably 30, daily dose units, each of which contain dienogest, cyproterone acetate, or chlormadinone acetate at a daily dose that is at most twice that required to inhibit ovulation together with one or more pharmaceutical aids and / or carriers. The daily dose units are administered in a method of prophylaxis and / or therapy of endometriosis continuously during a time interval of at least 169 days or 25 weeks, preferably more than two years. The method effectively reduces endometriosis and associated pain, while undesirable side effects including bone density decrease are reduced or eliminated.

A personal identification apparatus is disclosed by which personal identification can be performed making use of an impulse response obtained from a pulse signal transmitted by a living organism. A pulse generation section generates a pulse, and a speaker applies the pulse amplified by an amplifier to a finger of a user touching with the speaker and a microphone. The pulse signal is transmitted to the microphone with an attenuation characteristic that depends upon, for example, a transmission distance that depends upon the length and the thickness of the finger and characteristics of the living organism such as the thickness of the flesh and the bone density. A data synthesis processing section synthesizes the pulse and an impulse received by the microphone and amplified by an amplifier. A template recording section records a template to be used as a reference of discrimination in an authentication process together with a user ID and so forth. A comparison discrimination processing section refers to the template recording section to discriminate whether or not an impulse response inputted from a memory coincides with one of templates of registered users.

The invention discloses an ultrasound bone density measuring and analyzing system. The system comprises an ultrasound parameter measuring apparatus, a communication interface and a human machine interaction device, wherein the ultrasound parameter measuring apparatus comprises transmitting unit consisting of a pulse generator, a high-voltage pulse excitation module and a transmitting probe, an ultrasound receiving unit consisting of a receiving probe, a simulation pretreatment module, a gain adjustable amplifier, a phrase comparator, a high-speed ADC and an asynchronous FIFO, and a central processor, a power supply control module and a structural body. the human machine interaction device controls the ultrasound parameter measuring apparatus through the communication interface to measure the width of a calcaneus of a detected person, the transmission speed of an ultrasound wave in the calcaneus, broadband ultrasonic attenuation to calculate the bone intensity indexes and the bone density, so a medical report can be made according to diagnostic standards of osteoporosis and a special data base can be built for long term use. The system adopts wet or dry coupling and other technologies to improve the precision and accuracy of measure and has the advantages of easy carrying, low cost, no damage caused by radiation and can be use in long term monitoring of bone condition of the detected person.

The invention relates to new use of taurochenodeoxycholic acid, in particular to the new use of the taurochenodeoxycholic acid in prevention and treatment of osteoporosis. Through the study on taurochenodeoxycholic acid, the inventor found that the taurochenodeoxycholic acid can promote bone cells to secrete osteocalcin and improve lowered bone density. Thus, the taurochenodeoxycholic acid can beused in prevention or treatment of osteoporosis. After being administrated directly or being formed into various formulations, the taurochenodeoxycholic acid can be used for preventing or treating osteoporosis and other related diseases or states of osteoporosis.

A novel approach for analyzing a patient's body part of interest to assess bone strength and / or risk of future fracture includes obtaining a priori information regarding the body part of interest, performing X-ray absorptiometric scans of the patient's body part of interest and collecting X-ray absorptiometry data from the scans, constructing a three-dimensional model of the patient's body part of interest, by utilizing the a priori information along with the X-ray absorptiometric data, and performing measurements of various geometric parameters on the three-dimensional model for determining geometric and structural properties.

Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1a, R6, Xa, Xb and Y are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.

The invention relates to health food for enhancing human immunity and increasing bone mineral density and a preparation method thereof; the health food of the invention comprises the following components: hyaluronic acid, glucosamine, collagen, kudzu root extracts, chondroitin sulfate, vitamins, calcium, etc; because of the embedding processing of hyaluronic acid, the defect of property change of hyaluronic acid due to moisture absorption and influence of environmental factors is overcome; the health food prepared by the organic combination of the embedded hyaluronic acid with glucosamine, collagen, plant extracts, vitamins, mineral matter and the like has functions and effects which can supplement each other, has the effects of lubricating joints, increasing bone mineral density, and enhancing bone strength during long-term administration, and also has the functions of delaying aging, removing freckles and beautifying faces, and the like; the health food of the invention can be prepared into powder, granules, tablets, capsules, is convenient for carrying and taking, has stable and lasting efficacy, has no side effects, and is an ideal health food of patients with hypoimmunity and osteoporosis.

The invention discloses a bone examination apparatus which includes a shaking module, a multi-mode ultrasonic detecting module, and a processing module. The shaking module is disposed close to a distal end of an examinee's femur, for inputting a shaking signal to the distal end. The multi-mode ultrasonic detecting module is disposed close to a near end of the examinee's femur, for detecting the shaking signal through the examinee's femur at the near end and generating a detecting signal. Additionally, the processing module is connected to the shaking module and the multi-mode ultrasonic detecting module respectively, for determining the examinee's bone density in accordance with the shaking signal, the detecting signal, and a first criterion.

A process and osteodensitometry system using a dual-energy cone beam of X-rays is described. The system comprises an X-ray source capable of supplying a cone beam of X-rays with at least a first energy called the high energy and a second energy called the low energy, a two dimensional X-ray detector and electronic processor for processing images supplied by the detector. According to the process, a low energy image of a part of the anatomy of a patient, and a high energy image of the same part of the anatomy of a patient are acquired, and the images acquired at low energy and at high energy are matched before building up the map of bone densities of the part of the anatomy.

In an embodiment of the invention, a method of measuring bone density is provided comprising: irradiating a volume to be analyzed; for x-rays emerging from the irradiated volume, detecting at least two of transmitted x-rays, forward scattered x-rays and backward scattered x-rays; and analyzing at least two of the transmitted x-rays, the forward scattered x-rays, or the backward scattered x-rays to determine a density by determining at least one of a ratio of the forward scattered x-rays to the backward scattered x-rays, a ratio of the forward scattered x-rays to the transmitted x-rays, or the product of the ratio of the forward scattered x-rays to the backward scattered x-rays and the ratio of the forward scattered x-rays to the transmitted x-rays.

Disclosed is a dietary ingredient comprising at least one edible lipid which does not inhibit mineral absorption, enhances mineral absorption and intake, particularly a chemically or enzymatically synthesized synthetic oil, particularly glyceride-based lipid with high levels of mono- or polyunsaturated fatty acids at positions sn-1 and sn-3 of the glycerol backbone, vegetable- and plant-derived oil, such as flax and canola oils, short and medium chains lipid, preferably MCT and an oil mimicking the triglyceride composition of human mother's milk fat and its various uses.The dietary ingredient is particularly intended for use in enhancing calcium absorption and in the prevention and / or treatment of disorders associated with depletion of bone calcium and bone density, prevention and treatment of osteoporosis, for the enhancement of bone formation and bone mass maximization and for the enhancement of bone formation in infants and young children.

The present invention concerns a device for the calibration and standardization of the rotation and movement of a patient's hip. More particularly the present invention relates to a device for the calibration and standardization of the rotation and movement of the hip for use in connection with improving the reproducibility and accuracy of a diagnostic procedure such as, for example, bone density measurement using dual x-ray absorptiometry (DXA).

A method uses a computer and software to measure bone density and structure of the proximal femur of the hip from a volumetric set of images containing pixels representing x-ray attenuation of the subject which are acquired with three-dimensional X-ray imaging devices. The method automatically locates anatomical markers of the hip without operator interaction, automatically positions regions of interest (ROIs) for measurement, automatically determines bone density measures of the ROIs, and automatically reports the results for individual subjects. Bone density measurements of ROIs include the integral bone of the total hip and neck as well as trabecular bone. The method automatically identifies a three-dimensional region-of-interest (ROI) volume which includes the hip, determines a three-dimensional coordinate system referenced to the anatomy of the subject, analyzes the ROI volume to identify voxels in the volume which satisfy defined criteria, and determines a measure of bone structure.

Devices, tools, systems and methods for X-ray bone density measurement and imaging for radiography, fluoroscopy and related procedures. Portable, efficient peripheral bone density measurement and / or high resolution imaging and / or small field digital radiography of bone and other tissue, including tissue in the peripheral skeletal system, such as the arm, forearm, leg, hand and / or foot.

The invention discloses a method for preparing a positioning guide plate of oral and dental implants. The method comprises the following steps of 1) preparing a base plate with a ball plunger; 2) carrying out computerized tomography (CT) on an oral cavity with the base plate; 3) scanning to obtain model data; 4) building an oral cavity CT three-dimensional model; 5) debugging a threshold; 6) registering the model; 7) virtually implanting; 8) generating a navigation plate; and 9) preparing the positioning guide plate. By adopting the method, the factors such as bone density and blood vessels around the to-be-planted position of an alveolar socket of a sufferer are used to the maximal extent; and the accuracy of the dental implants is improved, so as to improve the survival rate of the dental implants. An implant model is guided into the registered three-dimensional model image to carry out virtual implanting, so that the implant efficiency of the dental implants is improved favorably; and the clinical operation time of a doctor and the clinic time of a patient are shortened.

The invention provides a healthy food capable of postponing aging of women, which is prepared from plant extract with estrogen-like effect, Spirulina, collagen powder and plant polyphenol. The healthy food has the functions on caring skin, strengthening body, improving bone density, lowering blood lipid, improving appetite, preventing cancer, resisting fatigue, improving immunity, and can excite young activity and prevent and postpone aging of middle and aged females.

A health-care food for increasing human bone density is proportionally prepared from shark cartilage powder, Ca supplement, VD, epimedium, aminoglucose D-hydrochloride, and chondroitin sulfate. Its preparing process is also disclosed.

The present invention relates to a nutritional composition for infants and / or toddlers comprising a lipid component which has a large lipid globule size, having a volume weighted mode diameter above 1.0 μm and / or with a diameter of 2 to 12 μm in a amount of at least 45 volume % based on total lipid. The composition can be used to increase bone mineral content and / or bone mass density, to prevent osteoporosis and / or osteopenia and for the further prevention of obesity.

The invention discloses a multicomponent traditional Chinese medicine containing composition for increasing bone mineral density and a preparation method thereof. The composition comprises the traditional Chinese medicine raw materials in parts by weight: 400-500 parts of herba epimedii, 400-500 parts of Rhizoma Drynariae, 300-400 parts of achyranthes root and also comprises the following nutritional substances in parts by weight: 75-95 parts of calcium carbonate, 40-60 parts of fish collagen powder, 20-38 parts of chondroitin sulfate, 5-6.2 parts of glucosamine hydrochloride, 10-13 parts of vitamin C and 0.0003-0.0004 parts of vitamin D. According to conventional process, an oral solid preparation is prepared by extracting herba epimedii, Rhizoma Drynariae and achyranthes root by ethanol and mixing the ethanol extract and the nutritional substances and appropriate amount of auxiliary materials. The medical composition provided by the invention has the function of increasing bone mineral density and can be used for prevention and assistant treatment of osteoporosis.

Process for use of an osteodensitometry system using dual-energy cone beam X-rays. The system (1) comprises an X-ray source (1a) capable of supplying a cone X-ray beam with at least a first energy called the high energy and a second energy called the low energy, a two dimensional X-ray detector (2) and electronic means (3a, 3b) for processing images supplied by this detector. According to this process, the low energy image of a part of the anatomy of a patient (1c) is acquired, and the high energy image of this part of the anatomy is acquired, and these images acquired at low energy and at high energy are matched before building up the map of bone densities of the part of the anatomy.

A sleeve that provides mechanical stimulation to the arm to prevent bone density loss. A primary goal of this product is to prevent bone density loss that occurs during extended space travel. For one embodiment, only the predefined frequency specifications had to be met (between 40 Hz and 60 Hz). By meeting these frequencies for a duration of 30 minutes the product will theoretically prevent the loss of bone density. Additionally, clinical trials will need to be conducted before this product can be marketed. The product includes of several mechanical vibrators attached to a sleeve. The vibrators are small unbalanced-mass motors which are similar to those found in cell phones. The motors are encased in dome shaped housings designed to reduce lateral vibrations along the arm. The product is controlled using an Arduino board attached to the sleeve that actuates the motors. The motors, in turn, provide the specified frequency to the arm for 30 minutes. The spacing of the motor housings was determined from PEA simulations. This resulted in the motors being spaced 2 in apart along the arm at 90° increments around the axis of the arm. The controller has a display that allows for user interaction and includes a session timer. In addition, this product is contemplated for use in reducing muscle atrophy, eliminating bed sores, and treating other ailments that can result from sedentary behavior.

This invention relates to a pharmaceutical composition for treatment of a bone disease comprising, as an active ingredient, a protein comprising an extracellular cysteine-rich domain, which is from the Frizzled receptor selected from the group consisting of mammalian animal-derived Frizzled 1, Frizzled 2, and Frizzled 7 and has activity of increasing bone mass, bone density, and / or bone strength, or a mutant of such domain having sequence identity of 85% or higher to the amino acid sequence of the domain and having activity of increasing bone mass, bone density, and / or bone strength, or a vector comprising a nucleic acid encoding the protein.