The invention discloses an ultra-high
dose rate radiotherapy plan
optimization system based on compensator modulation, and relates to the technical field of radiotherapy. A
data acquisition module is used for acquiring medical image data of a patient and receiving a clinical target; the clinical target comprises a target region prescription
dose, an organ-endangering limit and a minimum
dose rate threshold value required for triggering and maintaining a FLASH effect; and the FLASH
biological effect evaluation module is used for calculating FLASH biological effective
dose distribution corresponding to the physical
dose distribution through an embedded
biological effect model based on the input physical
dose distribution and
dose rate distribution. According to the method, the physical dose is converted into the accurate FLASH biological effective dose through the improved
linear quadratic model embedded with the FLASH correction factor, the target tumor killing effect is guaranteed,
normal tissue protection is enhanced with the help of the
tissue differentiation correction factor, the industrial pain point that the physical dose reaches the standard but the
biological effect does not reach the expectation is effectively solved, and the application prospect is wide. And the
treatment plan better meets the clinical
curative effect and safety core requirements.