35 results about "Particle therapy" patented technology

The invention relates to the technical field of particle therapy, and provides a vacuum membrane window structure and a processing method.The structure comprises a membrane window flange, a supporting lining net, a non-metal polymer film, a membrane window pressing plate, a first sealing piece and a second sealing piece; the membrane window flange is provided with an annular positioning part; the supporting lining net is arranged on the annular positioning part; the non-metal polymer film is arranged on the side, away from the annular positioning part, of the supporting lining net and plated with a metal layer. The film window pressing plate is arranged on the side, away from the supporting lining net, of the non-metal polymer film. The first sealing piece is arranged between the periphery of the supporting lining net and the non-metal polymer film, and the second sealing piece is arranged between the periphery of the annular positioning part and the periphery of the non-metal polymer film; the non-metal polymer film, the film plating layer and the supporting lining net are tightly attached together, so that the film thickness is greatly reduced, the vacuum performance of a single-layer film is better than that of an existing double-layer structure, energy loss, scattering and neutron yield during beam film penetrating are reduced, and beam quality and treatment precision are improved.

An accelerator capable of efficiently and satisfactorily extracting a beam is provided. A main magnet A101 applies a main magnetic field to a space between a plurality of main magnetic poles M202 arranged to face each other. An RF kicker M204 causes a beam circulating in a main magnetic field region to which the main magnetic field is applied to be displaced to outside of the main magnetic field region. An extraction channel magnetic field to extract the beam is generated. A canceling magnetic field generation device M214 is provided to be closer to an inner peripheral side than an extraction channel M207 and generates a canceling magnetic field with a polarity opposite to that of a disturbance magnetic field produced by an extraction channel.

The present application belongs to the technical field of high-end medical equipment. Disclosed are a multi-room particle therapy room, a radiotherapy system, and a particle accelerator movement method. The multi-room particle therapy room comprises a plurality of treatment rooms. The radiotherapy system comprises the multi-room particle therapy room and a particle accelerator. Each treatment room is provided with a beam window. The particle accelerator can move outside different treatment rooms and is aligned with the beam windows. The particle accelerator directs particle beams into the treatment rooms by means of the beam windows. The particle beams perform radiotherapy by means of therapy heads in the treatment rooms. The radiotherapy system is not provided with a dipole magnet or a quadrupole magnet. The plurality of treatment rooms share one particle accelerator. The particle accelerator is moved to the outside of the treatment room requiring the particle beam, and the particle beam is directed into the treatment room by means of the beam window. When the treatment in the treatment room is completed, the particle accelerator is moved to other treatment rooms requiring the particle beams and performs treatment work, thereby reducing the overall cost of the radiotherapy system and making proton therapy accessible.

The utility model belongs to the technical field of treatment auxiliary equipment, and discloses supporting and positioning equipment for patient treatment and a particle treatment system. The movable mechanism is connected with the bearing component so as to movably adjust the bearing component, and the movable mechanism comprises two groups of multidirectional adjusting mechanisms which are symmetrically connected to two end sides of the bearing component respectively; and the counterweight adjusting assembly is arranged on the movable mechanism. The auxiliary positioning device can effectively replace traditional auxiliary positioning equipment which is complex in structure and high in cost, can achieve multi-angle adjustment on the body position or the target area of the body of a patient, can guarantee the adjustment accuracy in the treatment process, has the outstanding advantages of being compact in structure, small in size, low in manufacturing cost, easy and convenient to maintain and the like, and is suitable for popularization and application. And particularly, a rotary rack and a six-dimensional robot can be replaced on the premise of ensuring the treatment precision in particle treatment.

To implement downsizing of an apparatus and highly accurate beam irradiation. An irradiation nozzle 4 that irradiates a target object Pt with a radiotherapy beam includes: a nozzle base part 42 fixed on a beam axis 40 through which the radiotherapy beam passes; and a nozzle tip part that irradiates the target object with the radiotherapy beam that has passed through the nozzle base part, in which the nozzle tip part is fixed at a first position when the target object is irradiated with the radiotherapy beam and is fixed at a second position when the target object is imaged, and a curved movement path in which the nozzle tip part is movable between the first position and the second position is provided.

The present disclosure relates to methods of selecting a treatment regimen for a subject having cancer (e.g., prostate cancer) by determining the presence of a mutation in the subject's tumor that makes the subject a candidate for particle therapy. Methods of treating the subject and determining relative dosage are also contemplated herein.

1. The name of the design product: dose simulation simulation device. 2. The use of the design product: for simulating beam current signals generated by an accelerator in a particle therapy system. 3. The design features of the design product: in shape. 4. The picture or photo that best indicates the design features: perspective view.

The application relates to a rotating volume intensity modulated particle therapy optimization system for a superconducting gantry, comprising: a data setting module configured to set optimization input data; an equation construction module configured to construct an augmented Lagrange equation, and replace an original optimization problem into an iterative form combined with an alternating direction multiplier method; an iterative optimization module configured to perform alternating direction multiplier method iterative optimization, and solve corresponding point array weights under the condition of meeting constraint conditions; a threshold pruning module configured to perform threshold pruning on the point array weights, and eliminate non-active points to obtain new point array weights; a condition judgment module configured to judge whether a set convergence condition is reached, and if not, repeat the setting step; and an optimization output module configured to output the point array weights and energy layer dose distribution proportions. The application reduces non-active point irradiation, significantly enhances the sparsity of scanning points in a selected energy segment, and adapts to the rapid energy conversion of the superconducting gantry in a large momentum acceptance energy segment.

The application discloses a PET imaging device, a PET device and a treatment system for multi-field particle therapy. The PET imaging device comprises: an identification unit configured to identify one or more time intervals of each field according to a time distribution feature of acquired single-event data, each time interval corresponding to a particle beam delivery state; a coincidence processing unit configured to perform coincidence processing on the single-event data to generate coincidence event data; and a reconstruction unit configured to perform image reconstruction on the coincidence event data in the identified time intervals of each field to obtain a corresponding reconstructed image of each field. Through intelligent identification of the time distribution feature and a partition reconstruction strategy, the application solves the problem of serious overlap of PET signals in a multi-field delivery mode, and realizes accurate extraction of independent dose distribution of each field and image reconstruction.

An example particle therapy system can include a synchrocyclotron to generate a particle beam, a scanner to move the particle beam in one or more dimensions relative to an irradiation target, and an energy degrader between the scanner and the irradiation target. The energy degrader can include a plurality of plates that are movable relative to a path of the particle beam and each controllable to move in the path of the particle beam and during movement of the particle beam. An aperture can be between the energy degrader and the irradiation target. The aperture can trim the particle beam before the particle beam reaches the irradiation target.

A beam delivery system for particle therapy is provided, which when combined with an appropriate patient positioning system, can effectively replace the large and cumbersome gantry systems traditionally used in particle therapy for example for treatment of cancer or other diseased tissue conditions. The system's modular design enables scalability, making particle therapy more accessible and affordable for a broader range of healthcare facilities and patients.

Described herein are compact particle therapy systems comprising a superconducting cyclotron for proton therapy applications. In some aspects, an electromagnetic beamline incorporating energy selection systems and pencil beam scanning magnets directs particle beams from the cyclotron to a treatment isocenter. A patient positioning device comprising a robotic positioner with six degrees of freedom supports patient alignment, t. The particle system can be ultra compact and able to be installed in existing photon linear accelerator (e.g., radiation therapy) vaults.

The present application relates to the technical field of particle therapy, and provides a vacuum film window structure and a processing method.The structure comprises a film window flange, a support mesh, a non-metallic polymer film, a film window pressing plate, a first sealing element and a second sealing element.The film window flange is provided with an annular positioning portion.The support mesh is arranged on the annular positioning portion.The non-metallic polymer film is arranged on one side of the support mesh away from the annular positioning portion, and the non-metallic polymer film is plated with a metal layer.The film window pressing plate is arranged on one side of the non-metallic polymer film away from the support mesh.The first sealing element is arranged between the periphery of the support mesh and the non-metallic polymer film, and the second sealing element is arranged between the periphery of the annular positioning portion and the periphery of the non-metallic polymer film.The non-metallic polymer film, the film plating layer and the support mesh are tightly adhered together, so that the film thickness is greatly reduced, the vacuum performance of the single-layer film is better than that of the existing double-layer structure, the energy loss, scattering and neutron yield when the beam passes through the film are reduced, and the beam quality and treatment accuracy are improved.

The utility model discloses a rotary particle treatment head curtain sealing structure, which belongs to the technical field of proton therapy, and comprises a hollow rack and a telescopic particle treatment head, a C-shaped mounting port is arranged on the inner side of the rack, the particle treatment head is rotatably arranged in the mounting port, a C-shaped first track is arranged in the rack, and a second track is arranged in the rack. And a C-shaped second rail is fixedly arranged between the two ends of the first rail. According to the rotary particle treatment head curtain sealing structure, the sliding frame on the first track is matched with the curtain to seal the particle treatment head and the rack, the second track is matched with the first track to enable the sliding frame to move along with rotation of the particle treatment head, and dust on the curtain is cleaned through the dust collection assembly at the second track. Compared with an existing device, the problem that dust falls into and is accumulated in a gap between the particle treatment head and the rack is solved, the stability of the device is improved, and the service life of the device is prolonged.

The invention belongs to the field of particle therapy, and discloses a multi-angle particle therapy system and a control method thereof.The multi-angle particle therapy system comprises a particle beam system, a bearing component, a multi-direction adjusting mechanism, a balance weight adjusting assembly and a control system.On the premise of not depending on a traditional large rotating rack and a six-dimensional robot therapy couch, the multi-angle particle therapy system can achieve multi-angle particle therapy; the multi-angle particle beam irradiation device achieves multi-angle particle beam irradiation on a target area of a patient, guarantees treatment precision, and meanwhile has the outstanding advantages of being compact in structure, small in size, low in manufacturing cost, easy and convenient to maintain and the like.

This application discloses a PET imaging method, electronic device, and storage medium for multi-field particle therapy. The PET imaging method includes: identifying one or more time intervals for each field based on the temporal distribution characteristics of acquired single-event data, with each time interval corresponding to a particle beam delivery state; performing conformation processing on the single-event data to generate conformation event data; and reconstructing images from the conformation event data in the identified time intervals of each field to obtain reconstructed images corresponding to each field. Through intelligent identification of temporal distribution characteristics and a partitioned reconstruction strategy, the method of this application solves the problem of severe aliasing of PET signals in multi-field delivery modes, achieving accurate extraction and image reconstruction of the independent dose distribution of each field.

The present disclosure generally relates to the methods of treating solid tumors using negatively charged particles.

The present disclosure relates to an automated device and methods to produce a highly purified alpha-emitting radioisotope Pb-212 from a pre-filled column of a parent isotope Ra-224 for use in targeted alpha-particle therapy.

To enhance the maintainability.SOLUTION: An ion source 3 that extracts an extraction beam 15 from an acceleration cavity A in a magnetic pole 1 includes a chimney 22, at least one cathode 23, a high-frequency acceleration electrode 8, and a dummy electrode 9. The chimney is fixed to the acceleration cavity. At least one cathode is disposed so as to be able to be inserted into the chimney. The cathode is one of a pair of cathodes inserted from both sides of the chimney and disposed to face each other. The high-frequency acceleration electrode accelerates the extraction beam. The dummy electrode is disposed opposite to or in parallel to the high-frequency acceleration electrode. The chimney is electrically connected to the dummy electrode through a contact piece C.SELECTED DRAWING: Figure 4

A beam angle optimization method for particle therapy comprises: receiving, by an analysis apparatus, distance information from a patient's body surface to a tumor, internal heterogeneity information, internal transmission information of a particle beam, and internal motion information according to the patient's respiration; inputting, by the analysis apparatus, the distance information from the patient's body surface to the tumor, the internal heterogeneity information, the internal transmission information of the particle beam, and the internal motion information according to the patient's respiration into a deep learning model; and calculating, by the analysis apparatus, a particle therapy beam angle based on an output value of the deep learning model.

The invention relates to the technical field of particle therapy equipment, and provides a rotary terminal vacuum docking mechanism and a manufacturing method.The rotary terminal vacuum docking mechanism is characterized in that a telescopic sealing assembly is provided with a closed driving cavity, a sealing connecting piece is arranged at one end of the telescopic sealing assembly, and a sealing face is arranged at the end of the sealing connecting piece; the sealing face is used for being matched with a pneumatic gate valve sealing face on the vacuum system side of a treatment room. The rough extraction sealing connecting piece is arranged at the other end of the telescopic sealing assembly; the driving cavity is configured to drive the sealing surface of the sealing connecting piece to move in the first direction by introducing or discharging a pressure medium; the axial movement of the sealing surface of the sealing connecting piece is realized by charging and discharging the pressure medium through the driving cavity, so that the requirement of frequently switching treatment rooms of the rotating terminal is met; after butt joint is completed, a beam channel is in a completely continuous vacuum environment, large energy loss, scattering and stray particles caused by butt joint of schemes such as a vacuum membrane window are effectively avoided, the treatment precision is improved, and the safety of a patient is guaranteed.

The application discloses a kind of orthogonal strip CZT detector module and method for particle therapy range and dose monitoring, orthogonal strip CZT detector module includes orthogonal strip CZT detector, signal front-end electronics circuit, channel compression circuit;Anode electrode and cathode electrode in orthogonal strip CZT detector are long strip and mutually orthogonal setting;Channel compression circuit reduces the channel number of signal output.According to user demand, the present application can realize the switching of single probe measurement mode and coincidence measurement mode, the method for monitoring the secondary particle intensity generated by the interaction of primary beam particles and human tissue in particle beam therapy field, the position and dose of particle primary beam irradiation target body or human body are calculated by secondary particle counting rule, so as to realize the monitoring of particle beam range and dose, the present application reduces the channel number of readout electronics and reduces the complexity of data acquisition, modular design meets the characteristics of economy and miniaturization.

The application relates to a scanning magnet system for radiotherapy, a first scanning coil is a first variable-aperture cylindrical scanning magnet, a second scanning coil is a second variable-aperture cylindrical scanning magnet, the first scanning coil is located on the radial inner side of the second scanning coil and is integrated with the second scanning coil through a framework, the first scanning coil is an X-direction scanning magnet, the second scanning coil is a Y-direction scanning magnet, both are coaxially arranged and define a conical air gap structure of the variable-aperture bidirectional scanning magnet to deflect a beam in a plane perpendicular to the beam direction Z. According to the scanning magnet system for radiotherapy, the variable-aperture mode is adopted to reduce the energy storage, thereby reducing the inductance, further reducing the requirement of the scanning magnet on the power supply, the originally separated scanning magnets are integrated through the framework, the space occupied by the scanning magnets is greatly reduced, the rotating gantry can be reduced, and the miniaturization and compactness of a particle therapy device can be realized.

The present application relates to particle therapy equipment technical field, provide a kind of rotating terminal vacuum docking mechanism and manufacturing method, retractable sealing assembly is provided with closed drive cavity, sealing connector is arranged at one end of retractable sealing assembly, the end of sealing connector is provided with sealing surface, and sealing surface is used to adapt with the pneumatic plug valve sealing surface of treatment room vacuum system side;Coarse pumping sealing connector is arranged at the other end of retractable sealing assembly;Drive cavity is configured to be driven by the sealing surface of sealing connector by passing in or discharging pressure medium to move along the first direction;The present application realizes the axial movement of the sealing surface of sealing connector by the pressure medium of drive cavity filling and discharging, to meet the needs of rotating terminal frequently switching treatment room;After docking is completed, beam channel is completely continuous vacuum environment, effectively avoid using vacuum film window and other solutions to dock to cause greater energy loss, scattering and stray particles to treatment beam, improve treatment precision, guarantee patient safety.

A beam delivery system for particle therapy is provided, which when combined with an appropriate patient positioning system, can effectively replace the large and cumbersome gantry systems traditionally used in particle therapy for example for treatment of cancer or other diseased tissue conditions. The system's modular design enables scalability, making particle therapy more accessible and affordable for a broader range of healthcare facilities and patients.

The present disclosure relates to an automated device and method for producing a high purity alpha particle-emitting radioisotope Pb-212 from a column pre-filled with the parent isotope Ra-224 for targeted alpha particle therapy.

A method for generating a range modulating device for radiotherapy includes obtaining a medical image of a patient. The method further includes determining, using the medical image, a design of a range modulating device having non-uniform density for radiotherapy for the patient. The method further includes 3D printing, using the design, the range modulating device by continuously varying the ratio of filament to air in each voxel of a plurality of voxels. The method can also include performing radiotherapy on the patient by inserting the range modulating device in a beam path between a beam from a radiation source and the patient.

The application belongs to the field of particle therapy, and discloses a multi-angle particle therapy system and a control method thereof. The multi-angle particle therapy system comprises a particle beam system, a bearing component, a multi-direction adjusting mechanism, a counterweight adjusting assembly and a control system. The application can realize multi-angle particle beam irradiation on a target area of a patient without relying on a traditional large rotating gantry and a six-dimensional robot treatment bed, and has the advantages of compact structure, small volume, low manufacturing cost, simple maintenance and the like while ensuring treatment accuracy.

The utility model relates to the technical field of particle therapeutic apparatus auxiliary devices, and discloses a supporting device for a particle therapeutic apparatus rotating cylinder, and cylinder necks at two ends of the rotating cylinder are respectively provided with a rotating track; corresponding to the rotating tracks at the two ends of the rotating cylinder, the supporting device is provided with two groups of supporting frames which are arranged at intervals; each supporting frame is provided with a bearing frame body, a bearing bush and a hydraulic mechanism, wherein the bearing bush and the hydraulic mechanism are arranged on the bearing frame body. The bearing frame body supports the rotating cylinder at the corresponding rotating track of the rotating cylinder through the bearing bush. A static pressure oil cavity is formed in the bearing surface of the bearing bush, and a plurality of oil inlet holes communicated with the hydraulic mechanism are distributed in the static pressure oil cavity; the supporting frame supports the rotating cylinder in a suspension mode through a hydraulic mechanism. According to the utility model, the suspension support of the rotating cylinder can be realized, the friction between the rotating cylinder and the support frame during the operation is effectively reduced, the deformation of the rotating cylinder and the support frame can be effectively reduced, the rotating precision and stability during the operation of the rotating cylinder are ensured, and the abrasion and maintenance cost of equipment are reduced.