197 results about "Doses rate" patented technology

The invention discloses a nuclear radiation index early warning system based on multi-algorithm fusion, and the system comprises an environment data collection module which is used for collecting gamma-ray dose rate data, wind speed data, wind direction data and geographic position information, and constructing a nuclear radiation environment data set; the dose rate prediction module is used for predicting a future change trend of gamma ray dose rate data based on a sparse recurrent neural network model; the anomaly detection module is used for identifying an abnormal mutation point and positioning the position of a high-risk sensor; the diffusion region modeling module is used for calculating a nuclear radiation diffusion influence region; the grid risk evolution module is used for simulating time sequence evolution of a regular grid risk state based on the multi-state cellular automaton; and the fusion judgment module is used for fusing output results and generating a final early warning grade and a spatial risk distribution result. According to the invention, accurate prediction of the nuclear radiation risk and dynamic space early warning are realized, and the early warning accuracy and response efficiency are significantly improved.

The invention provides a microdosimetry-based evaluation method for a targeted alpha radionuclide treatment biological effective dose, and the method comprises the steps: carrying out the integration of a time activity curve of alpha radionuclide in an organ, obtaining the cumulative activity, and calculating the physical absorbed dose and dose rate of the organ through Monte Carlo simulation; based on micro-dose Monte Carlo simulation, constructing a micro-dose spectrum of the alpha radionuclide to obtain saturation correction dose average linear energy for representing radiation quality; obtaining biological effect parameters of the alpha radionuclide by fitting saturation correction dose average line energy and cell experiment data by using a micro-dose kinetic model; and evaluating the biological effective dose of the target organ in combination with the physical absorbed dose, the dose rate and the biological effect parameter. According to the method, the problem that a biological effective dose evaluation method is lacked in dose evaluation of targeted alpha radionuclide treatment is solved.

A method of planning radiation treatment for a patient includes identifying a region of interest of the patient to be treated with radiation and determining a simulated treatment plan for the region of interest based on a statistical analysis between one or more metrics of the identified region of interest and a previously determined predictive dynamics database that includes information regarding the one or more metrics for corresponding regions of interest for a population of patients. The method further includes characterizing the simulated treatment plan with a FLASH Index that compares an ideal FLASH radiation treatment plan to the simulated treatment plan.

The invention discloses an ultra-high dose rate radiotherapy plan optimization system based on compensator modulation, and relates to the technical field of radiotherapy. A data acquisition module is used for acquiring medical image data of a patient and receiving a clinical target; the clinical target comprises a target region prescription dose, an organ-endangering limit and a minimum dose rate threshold value required for triggering and maintaining a FLASH effect; and the FLASH biological effect evaluation module is used for calculating FLASH biological effective dose distribution corresponding to the physical dose distribution through an embedded biological effect model based on the input physical dose distribution and dose rate distribution. According to the method, the physical dose is converted into the accurate FLASH biological effective dose through the improved linear quadratic model embedded with the FLASH correction factor, the target tumor killing effect is guaranteed, normal tissue protection is enhanced with the help of the tissue differentiation correction factor, the industrial pain point that the physical dose reaches the standard but the biological effect does not reach the expectation is effectively solved, and the application prospect is wide. And the treatment plan better meets the clinical curative effect and safety core requirements.

The invention provides a signal processing method for radioactivity detection equipment and the radioactivity detection equipment, and the signal processing method for the radioactivity detection equipment comprises the steps: analyzing a collected nuclear pulse signal, and obtaining pulse amplitude information; performing spectrum stabilization according to the pulse amplitude information to obtain a spectrum-stabilized energy spectrum; and determining a nuclide identification result and a dose rate calculation result based on the spectrum-stabilized energy spectrum. According to the technical scheme, on one hand, the current environment dose rate level can be determined, it is ensured that the radiation dose received by workers is within the safety limit value, and therefore the radiation risk can be reduced, and the health and safety of the workers are guaranteed; and on the other hand, specific radionuclides can be identified, so that the pollution source can be determined.

The present disclosure relates to the field of radiotherapy, in particular, methods of and apparatus for treating cancer using ultra-high dose rate radiotherapy (FLASH). The apparatus may comprise a device configured to administer to the subject no more than five fractions of proton ultra-high dose rate radiotherapy (FLASH), said fractions having a range of radiation from 1.5 Gy to 60 Gy, collectively. The device may be configured such that the treatment is sufficient to prevent further growth of the tumor for at least 10% longer than standard of care radiotherapy, induce at least 10% more tumor regression than standard of care radiotherapy and / or delay tumor regrowth by at least about 2 months longer than standard of care radiotherapy.

The invention provides a rack for radiotherapy equipment and the radiotherapy equipment. The rack for the radiotherapy equipment comprises a supporting assembly; the roller is configured to be of a horizontal structure and is provided with an axial first end and an axial second end, and the first end and the second end are rotationally arranged on the supporting assembly; and the bearing frame is arranged on the outer wall of the first end and is suitable for bearing an external pulse transformer, so that the pulse transformer synchronously rotates along with the roller. The roller is suitable for providing a reliable mounting platform for the ultrahigh-dose-rate radiotherapy equipment, so that particle rays output by a plurality of beam modules configured on the ultrahigh-dose-rate radiotherapy equipment can be accurately converged in the roller. The first end and the second end of the roller are rotatably arranged on the supporting assembly so as to meet the requirement for bearing capacity required by the roller and other configured assemblies, so that the rack for the radiotherapy equipment forms a reliable mounting platform. The bearing frame is used for assembling the pulse transformer on the roller and moves along with the roller.

The invention relates to a low-pressure ionization chamber, a design method and a medical linear accelerator, and belongs to the technical field of radiotherapy dose monitoring, the low-pressure ionization chamber comprises a shell, a closed cavity is formed in the shell, a low-pressure environment lower than standard atmospheric pressure is formed in the closed cavity, and the ion recombination ratio of positive and negative charges is not larger than 0.01; according to the invention, the technical problem in the prior art that the monitoring result is inaccurate under the ultrahigh dose rate due to the influence of ion recombination on the penetration type air ionization chamber can be solved.

The invention provides an interlocking protection optimization system and method of a FLASH accelerator and electronic equipment, and the system comprises an acceleration module which is used for generating an initial electron beam and accelerating the initial electron beam to obtain a high-energy electron beam; the beam quality guarantee module is in signal connection with the acceleration module and is used for monitoring, regulating and controlling the intensity and the position of the high-energy electron beam in real time; the treatment execution module is in signal connection with the beam quality guarantee module and is used for converting the high-energy electron beams into treatment rays and monitoring the output dose of the treatment rays in real time; and a safety interlocking protection module which is in signal connection with the acceleration module, the beam quality guarantee module and the treatment execution module and is used for collecting operation parameters of all parts of the FLASH accelerator in real time, performing analysis based on preset logic, triggering interlocking protection actions under abnormal working conditions, and controlling the treatment execution module to perform treatment. And active monitoring-intelligent analysis-rapid response closed-loop control of the ultrahigh dose rate radiotherapy accelerator in a full operation period is realized.

The invention relates to the technical field of accelerator radiation protection, in particular to an induced radioactivity assessment method suitable for a mobile accelerator component. Monte Carlo simulation software is adopted to calculate radionuclide activity concentrations in different areas of an acceleration component before movement, then radionuclides serve as radiation source items, and three-dimensional space dose rate distribution of the component and the periphery when the position of the accelerator component changes is obtained through calculation. And rapid evaluation of the received dose of the staff during maintenance and rapid formulation of a maintenance scheme are realized. The method effectively promotes the application of the Monte Carlo method in the field of radiation protection of the accelerator, provides reference for radiation hazards to workers, and provides technical support for radiation protection and operation maintenance of the accelerator.

The invention provides a construction method of a radioactive esophageal injury organ-like model. The construction method comprises the following steps: performing X-ray ionizing radiation on esophageal organs; wherein the esophageal organ comprises a rat esophageal organ, a mouse esophageal organ or a human esophageal organ; the radiation dosage is 0.5 to 4 Gy, and the radiation dosage rate is 1.5 to 2 Gy / min. Experimental results show that along with increase of irradiation dose, connection around spheres of human esophageal organs, mouse esophageal organs and rat esophageal organs is loose, cell debris is increased, and the sizes are smaller than those of normal organs at the same time. The construction of the radioactive esophageal injury organ-like model is of great significance for deeply understanding the injury mechanism of ionizing radiation to the esophagus, searching for effective protection and treatment measures and promoting the development of personalized radiotherapy.

The invention discloses a helium-bubble-induced numerical simulation method and system for performance degradation of a critical component material of an inspection and maintenance robot, and relates to the technical field of numerical simulation. Firstly, experimental data of the critical component material in a nuclear radiation environment are collected and analyzed, and an SRIM / TRIM simulation model is utilized to quantify initial conditions of irradiation damage; the method comprises the following steps of: firstly, acquiring key data, then simulating an atomic scale related process by means of LAMMPS molecular dynamics to obtain key data, then performing data conversion in Python to obtain equivalent porosity, and finally researching a material performance degradation rule through ABAQUS. Influences of various factors of helium bubbles on the material performance are comprehensively considered, and accurate prediction is achieved; through numerical simulation, the performance degradation condition of the material under different helium bubble sizes, numbers and dosage rates can be rapidly evaluated, and the evaluation efficiency is greatly improved. Meanwhile, the accuracy of a numerical simulation result is ensured through experimental verification, so that an evaluation result is more reliable.

The invention relates to a gamma radiation field simulation method, a gamma radiation monitoring simulation training system and application of the gamma radiation field simulation method and the gamma radiation monitoring simulation training system, and a three-dimensional simulation gamma radiation field and the gamma radiation monitoring simulation training system are constructed based on the Beidou positioning technology, the computer and communication technology and the action law of gamma rays and substances. The simulation training system is composed of a guide center, a Beidou positioning and communication base station, a simulation training ground, a simulation gamma radioactive source and a simulation gamma radiation monitor. The parts of the system exchange information through wired or wireless communication. The simulated gamma radiation source and the simulated gamma radiation monitor both have an accurate positioning function, and the simulated gamma radiation monitor also has a function of calculating and obtaining a gamma radiation dose rate and a dose. The problem of simulation and monitoring simulation training of a space gamma radiation field generated by a plurality of real gamma radioactive sources is solved, so that the effects of simulation training such as searching for more than one gamma radioactive source, determining gamma radioactive contamination boundaries and measuring personal accumulated doses are close to reality.

The invention provides a method and a device for rapidly detecting nuclide activity concentration of mine barren rock, and relates to the technical field of nuclide detection. According to the method, the total dose rate of each detection point is detected when the to-be-detected mine waste rock passes through the gate-type channel, the dose rate equation set is constructed in combination with the preset dose rate conversion coefficient of each decay system nuclide, the dose rate equation set is combined for solving, and the activity concentration of each decay system nuclide in the mine waste rock is obtained. Rapid detection of the activity concentration of the nuclide in the mine barren rock is realized, and the detection efficiency of nuclide detection in the mine barren rock is improved.

Radiotherapy is the most widely used and effective anti-tumor therapy, however it can damage healthy tissues surrounding the tumor. One approach to reducing damage to healthy tissue involves irradiation at dose rates far exceeding those currently used in clinical contexts reduces radiation-induced toxicities while maintaining an equivalent tumor response. This is known as the FLASH effect. The mechanism responsible for reduced tissue toxicity following FLASH radiotherapy (FLASH-RT) is still undetermined; multiple hypotheses have been suggested by linking the high dose rate to rapid oxygen depletion, immune response, reduction of peroxyl radical lifetime, preservation of normal tissue stem cells, etc. While effective, proton therapy is underutilized, contributing to fewer than 2% of all external beam radiation treatments. To overcome this shortcoming, provided are methods which utilize the highest energy layer and a universal range shifter (URS) to facilitate rapid spot arc therapy (RAPIDSPARC™).

Described is a device for radiotherapy treatment with a high dose rate of ionizing radiation, comprising an accelerating guide (11) of a medical radiofrequency accelerator, at least two simultaneously thermostated resonant cavities (10) and comprising a first pick-up (12), a second pick-up (12B) in at least two resonant cavities (10) and an optical system (20) of the beam.

The invention provides a multi-radioactive-source air intelligent searching and positioning method, which comprises the following steps of: 1, constructing an earth surface radioactivity distribution diagram based on known radioactive sources under the condition of known multi-radioactive-source nuclide types and source intensities; 2, training a dose rate distribution diagram at the 1m position of the radioactive source earth surface based on a convolutional neural network; 3, performing full-coverage search monitoring on the to-be-searched area; 4, generating a dose rate distribution diagram at the 1m position of the earth surface of the to-be-searched area; 5, analyzing the dose rate distribution diagram based on a convolutional neural network; and 6, accurately measuring the position of the radioactive source. Under the condition of unknown multi-radioactive source nuclide type and source intensity, the method comprises the following steps: A, carrying out full-coverage search monitoring on a to-be-searched area; b, clearly optimizing a monitoring area based on the dose rate distribution diagram; c, performing automatic searching based on the optimized monitoring area; and D, determining the specific position of the radioactive source based on a parameter estimation method. According to the invention, the air searching and positioning of multiple radioactive sources can be accurately determined, and the searching efficiency is maximized.

The invention relates to the technical field of medical X-ray, radio frequency and high-frequency diagnosis and treatment equipment, in particular to a full-static X-ray radiotherapy system and method. The system is composed of an electron source, an accelerating cavity, a two-dimensional deflector, an annular magnet set, a strip-shaped anode target, a multi-leaf collimator set, a vacuum cavity and the like. The electron beam enters the two-dimensional deflector after being accelerated, and any plane angle is obtained under the pure electromagnetic action; and then the X-rays are guided to the strip-shaped anode target along each electron channel in an annular magnetic field of the annular magnet group to bombard and generate the X-rays. The multi-leaf collimator performs spatial modulation on rays to form an irradiation field matched with a target region, so that multi-angle high-precision radiation irradiation without mechanical rotation is realized. The strip-shaped target surface increases the heat dissipation area and cooperates with an efficient cooling loop, so that the dose rate upper limit is improved, and the FLASH radiotherapy requirement is met. The scheme is compact in structure, low in cost and simple and convenient to maintain, overcomes the defects of large size, low efficiency, limited dosage and the like of traditional rotary radiotherapy equipment, and has wide clinical popularization value.

The invention provides an accelerator system adjustment method, an accelerator system, electronic equipment and a storage medium. The transmission characteristic data and the charge quantity data of the undeflected beam are obtained through the first beam position detector, and the form and the charge quantity of the undeflected beam are accurately adjusted in combination with a preset adjustment strategy, so that the stability of beam transmission is ensured. And after the form data of the first beam reaches a preset value, monitoring the deflected beam data by using a second beam position detector, and further accurately adjusting the accelerator system to ensure that the deflected beam conforms to the target transmission characteristics. According to the invention, the transmission state of the beam can be accurately controlled in real time, risks of vacuum box breakdown and the like caused by beam mismatch are avoided, the safety and the stability of the system are improved, the possibility of equipment damage is obviously reduced especially under the high-dose-rate transient beam, and the treatment effect and the continuity of Flash radiotherapy are guaranteed.

The invention relates to a nuclear medicine medication nursing radioactive operation safety warning and evaluation system. The system comprises a sensing acquisition module, a behavior identification module, a dose evaluation module, a risk evaluation module, a risk grade division module, a warning and intervention module, a data storage and tracing module and a self-adaptive learning module. The system can collect parameters such as environment dose rate, individual dose rate, operation distance and time in real time in the processes of nuclear medicine preparation, split charging, injection and waste liquid disposal, analyze operation behaviors of nursing personnel in combination with action recognition results, dynamically calculate accumulated dose, and improve the accuracy of the operation of the nursing personnel. Risk indexes are constructed by comprehensively considering factors such as dosage ratio, liquid medicine residue activity and violation probability, and graded early warning is carried out; when the risk level exceeds a threshold value, triggering acousto-optic and terminal prompt, and generating an operation log for tracing; the system has data storage and self-adaptive optimization functions at the same time, model parameters can be corrected according to historical risk data, and long-term dynamic optimization is achieved.

This invention discloses a method for estimating radioactive release during the preparation of radioactive metal waste, comprising the following steps: (1) conducting gamma dose rate surveys and delineating the distribution of radioactive pollution in the radioactive source area; (2) setting up monitoring points in the radioactive metal waste areas with different pollution levels, and calculating the radioactive residue in the metal waste based on the monitoring data; (3) calculating the total release of each nuclide in the metal waste based on the above-mentioned radioactive residue in the metal waste and the obtained concentration data of radionuclides in the metal waste. By conducting gamma dose rate surveys and delineating the distribution of radioactive pollution in the radioactive source area; setting up monitoring points in the delineated areas to obtain the radioactive residue in the metal waste; and calculating the total release of each nuclide using formulas, the process is simple, easy to operate, and can obtain effective data on the total release of nuclides, providing data support for the preparation of radioactive contaminated metal waste and supporting the assessment of the dose caused by contaminated metal waste to the public.

A medical linear accelerator configured to operate in radiotherapy may have an electron gun for emitting an electron beam. An accelerator waveguide accelerates the electron beam. A linear accelerator head defines an inner beam passage for directing the electron beam. A beam current transformer in the linear accelerator head is for monitoring the electron beam An electrostatic shield is provided in the inner beam passage, the electrostatic shield being positioned downstream of the beam current transformer for shielding the beam current transformer.

The invention relates to the field of gamma dose rate monitoring, and provides a high-altitude radioactive point source dose rate distribution analysis method and system, and the method comprises the steps: collecting original counting data and energy spectrum data, and obtaining environment parameter data and flight carrier position information; performing statistical calculation on the original counting data to obtain counting statistical parameters; performing nonlinear correction on the original counting data, the energy spectrum data, the environmental parameter data and the counting statistical parameters to obtain corrected detector data and measurement uncertainty; performing fusion calculation on the corrected detector data to obtain a fusion weight, and performing verification processing to obtain fusion dose rate data; performing prediction processing on the fused dose rate data and the environmental parameter data to obtain a range switching signal; and performing reconstruction processing on the fused dose rate data, the range switching signal, the measurement uncertainty and the flight carrier position information to obtain ground dose rate distribution data. According to the invention, the accuracy and reliability of high-altitude radioactive point source dose rate distribution analysis are improved.

The present invention discloses a Flash beam dose control method and related equipment, and relates to the technical field of particle therapy, wherein the method comprises: obtaining a Flash beam output dose requirement; controlling the number of pulse periods of an output beam charge within a preset time through a Flash debugging mode; and / or controlling the pulse width of an ion source voltage through a pulse width mapping curve to achieve control of the Flash beam output dose rate; by accurately controlling the number of pulse periods of the output beam charge and the pulse width of the ion source voltage, accurate control of the Flash beam output dose rate can be achieved; and without additionally adding a shielding function to a proton machine room, the Flash dose can be debugged in a conventional proton machine room, which is conducive to the realization of particle Flash radiotherapy.

The utility model relates to the technical field of medical equipment, in particular to a flash therapy device for small animal radiotherapy and a control system. The ray source can emit rays to a treatment area of the flash therapy device, the shielding part is driven by a power mechanism and can move relative to the emitting end of the ray source, and the shielding part has a deviation state in which the rays emitted by the ray source can be irradiated to the treatment area and a shielding state in which the rays cannot be irradiated to the treatment area in the movement process; wherein in a movement period, the shielding part is initially in a shielding state, and after rays emitted by the ray source reach a set dose rate, the shielding part moves at a preset movement speed, so that the shielding part resets to the shielding state and stops moving after the movement of the shielding part is converted to a deviation state. According to the utility model, the influence on the total dose and the dose rate of ray irradiation treatment when the ray source is turned on and turned off can be eliminated, and the accurate total dose and the stable dose rate of the irradiation treatment in flash therapy are ensured.

The invention discloses a laminated modularized multifunctional radioactivity measuring device which comprises a measuring robot, a temporary storage layer and a plurality of measuring layers, the temporary storage layer and the measuring layers are sequentially arranged on the measuring robot from top to bottom, the measuring layers are connected in a laminated mode, a plurality of temporary storage bins are arranged in the temporary storage layer, and a receding area is formed in the bottom of the measuring robot. The measuring robot moves to the position above a waste bin storing radioactive waste, the waste bin is located in the receding area, the radioactive waste is transferred into the corresponding waste bin according to the measurement result of radioactive measurement, and a camera for positioning and recognizing the waste bin is arranged at the bottom of the measuring robot. The radioactive waste after dose rate preliminary screening can be further classified and subjected to radioactivity measurement, then the radioactive waste is sorted into the corresponding waste barrels based on the measurement result of radioactivity measurement, unmanned and automatic operation is achieved, and the multiple measurement layers meet different radioactivity measurement requirements.

The embodiment of the invention provides an energy response compensation method of a dose rate value and a chip. The energy response compensation method of the dose rate value comprises the following steps: acquiring the number of pulses generated by radioactive rays in each energy response compensation area; and according to each pulse number and the weight corresponding to each energy response compensation area, obtaining a dose rate value after energy response compensation. The dose rate value energy response compensation method provided by the embodiment of the invention is relatively high in accuracy.

As the ion beam is accelerated, the radius of the spiral orbit gradually increases, and the center of the spiral orbit moves in the predetermined radial direction of the gap toward the direction close to the peripheral portion, and then the moving direction of the spiral orbit is reversed and further moves toward the center of the gap. To achieve this, the intensity distribution in the orbit plane of the main magnetic field is designed. Thus, as a small accelerator capable of changing the energy of the extracted beam, the efficiency of beam injection from the external ion source into the accelerator is improved, and as a result, the dose rate of the extracted ion beam is improved.

A cabinet irradiator incorporates an x-ray tube, a moveable sample stage, dosimeter, and a real-time camera. A computing device receives video data from the real-time camera and based on the video data the computing device manipulates the sample stage height vertically in relationship to the sample chamber floor and the output window of the x-ray tube to be able to deliver the maximum dose rate to the entire sample as quickly as possible. A real-time image is captured and the image is correlated to move the sample stage vertically attaining a closer proximity to the exit window of the x-ray tube to attain and maximize dosage received by the sample in the shortest duration of time and operating the system to attain the desired prescribed dose.