119 results about "Contrast imaging" patented technology

The invention relates to the field of industrial visual inspection, and discloses an ultraviolet visible light confocal object image double telecentric imaging optical system which comprises a first lens, a second lens, a first gluing piece, a diaphragm, a second gluing piece, a third lens and a fourth lens which are sequentially arranged from an object plane to an image plane, and an optical axis serves as a rotation center. Wherein the object surface of the first lens is a convex spherical surface, the curvature radius of the first lens is 110.02 mm, the image surface of the first lens is a concave spherical surface, and the curvature radius of the first lens is 65.59 mm; the object surface of the second lens is a concave spherical surface, the curvature radius of the second lens is-200.11 mm, the image surface of the second lens is a convex spherical surface, and the curvature radius of the second lens is-130.80 mm. The system can be suitable for measuring an object with the object distance of 110 mm and an industrial camera with the imaging image surface diameter of 11 mm or below, the aperture of the system is F / 8, the system is also suitable for ultraviolet and visible light environments, it is ensured that lossless and high-contrast imaging can still be achieved in different light source environments, and therefore high-precision and high-reliability surface defect recognition and classification tasks are supported.

Laser speckle contrast imaging techniques that apply a temporal sliding window to a sequence of speckle frames of an avian egg to determine overlapping sets of speckle frames used to reconstruct a sequence of extraembryonic blood vessel images (e.g., movie) showing blood flow dynamics, and where input to a machine learning model based on the overlapping sets of speckle frames can be used to predict the developmental stage of the avian egg, and where the overlapping sets of speckle frames can be used in drug screening.

A system and method for visualizing blood flow are disclosed. The method generally includes obtaining a laser speckle contrast imaging (LSCI) image of blood flow; obtaining a white light image of a tissue, the white light image capturing an anatomical structure of a subject in a region associated with the LSCI image of the blood flow; spatially registering the LSCI image and the white light image with one another; overlaying the spatially registered LSCI and white light images; and generating display data which includes the spatially registered LSCI and white light images and that continuously depicts the blood flow overlaying the tissue.

The invention relates to the technical field of medical image processing, in particular to a super-resolution reconstruction method for optimizing an alimentary canal air-barium double contrast contrast image. Comprising the following steps: acquiring a low-resolution image sequence of digestive tract air-barium double contrast radiography acquired by an image acquisition module; dynamically capturing a long-distance dependency relationship between position image elements in the low-resolution image sequence through a self-attention mechanism, and generating a feature representation reflecting context association between sequence images; based on the feature representation and local detail features in a single image in the low-resolution image sequence, generating a high-resolution image sequence containing more suspected focus detail information; and optimizing the details of the alimentary canal air-barium double contrast contrast image according to the high-resolution image sequence so as to assist in displaying the alimentary canal organ mucosa plica microstructure and the cavity form, thereby completing the super-resolution reconstruction of the alimentary canal air-barium double contrast contrast image optimization. The method obviously improves the image quality of digestive tract air-barium double contrast radiography.

The embodiment of the invention provides a magnetic resonance imaging method and related equipment. The magnetic resonance imaging method comprises the following steps: applying a multi-spin echo sequence in each magnetization reset period, and collecting a group of multi-spin echo data sets until M groups of multi-spin echo data sets are obtained; after each magnetization reset period, a T1rho preparation pulse with spin locking duration is applied, then a multi-gradient echo sequence is applied, a group of multi-gradient echo data sets are collected until M groups of multi-gradient echo data sets are obtained, and the M groups of multi-spin echo data sets and the M groups of multi-gradient echo data sets correspond to M different spin locking durations respectively; and performing fitting operation on the M groups of multi-spin echo data sets and the M groups of multi-gradient echo data sets to generate a quantitative atlas. According to the technical scheme, the problems that a traditional T1rho sequence is long in scanning time, low in signal-to-noise ratio and single in contrast ratio are effectively solved, and the technical effects of time multiplexing and multi-contrast imaging are achieved.

This application relates to a fully automated method and apparatus for quantitative analysis of myocardial acoustic contrast imaging. The method includes: acquiring myocardial acoustic contrast imaging images; segmenting the acquired myocardial acoustic contrast imaging images to obtain myocardial segmentation images; calculating the cardiac chamber area based on the myocardial segmentation images; automatically extracting the myocardial segmentation results at the end of cardiac systole using the periodic changes in cardiac chamber area; using the extracted end-systolic segmentation results as a mask to extract the corresponding position of each image as a target region for registration, thereby generating a one-to-one correspondence of registered image sequences; fitting a function model based on the pixel values ​​of each point in the registered image sequence; and generating a parametric image based on the registered image sequence and the fitted function model. Therefore, this application can perform fully automated quantitative analysis of myocardial acoustic contrast imaging.

The present disclosure relates to a 3D and / or 4D ultrasound contrast imaging device, a 3D and / or 4D ultrasound contrast imaging method and a medium. The method includes: receiving an input for selecting a 3D contrast imaging mode or a 4D contrast imaging mode; receiving an input for setting an imaging speed, including a first imaging speed and a higher second imaging speed; and controlling the device with imaging parameters associated with the selected contrast imaging mode and the set imaging speed to achieve imaging in the selected contrast imaging mode at the set imaging speed, the association of the imaging parameter and the imaging speed enables the data volume required for generating each image at the first imaging speed to be greater than the data volume required for generating each image at the second imaging speed. Thus, a user can freely select an expected contrast imaging mode and imaging speed, imaging parameters are acquired in a targeted mode, and the real-time observation requirement of a doctor can be met under the conditions that the data processing capacity is limited and various probes are used.

This invention discloses a beam expander lens for laser scanning projection, relating to the field of laser projection display technology. It includes a first lens group, a second lens group, a third lens group, and a fourth lens group, arranged sequentially along the optical axis. These four lens groups together form the complete lens. The first, second, third, and fourth lens groups are arranged in a positive-negative-negative-negative optical power configuration. Through innovative optical architecture and optical power allocation, a large-angle beam expander function is achieved within a space of less than 35mm in total length, greatly saving internal space. By utilizing the chromatic aberration correction capability of the first lens group and the aberration correction capabilities of the second, third, and fourth lens groups, high-contrast imaging is achieved across the entire field of view and wavelength range, with concentrated dot matrix energy, meeting the requirements of high-resolution projection.

This invention discloses a low-pass filtered non-breath-hold saline angiography combined with cardiac mirror contrast imaging for lung perfusion imaging, belonging to the field of medical imaging technology. The method includes the following steps: S1: determining whether the subject's tidal impedance variation meets the imaging criteria; S2: injecting contrast agent into the subject to perform angiography; S3: obtaining an impedance decrease signal; S4: combining cardiac mirror contrast imaging with lung perfusion images. This invention solves the problem of low success rate of saline angiography in existing technologies, achieves separation of thoracic impedance caused by tidal breathing and thoracic impedance caused by saline angiography, reduces the influence of the cardiac region on lung perfusion images, further improves the accuracy of lung perfusion imaging, greatly reduces the interference of breath-holding on respiratory circulation, improves the simplicity of clinical application, and expands clinical application scenarios.

This application relates to the field of image information processing technology and provides a fusion contrast imaging method, a registration method and apparatus for intracavitary images and contrast images. The fusion contrast imaging method includes: acquiring contrast images and intracavitary images; fusing the contrast images and intracavitary images based on the correspondence between contrast markers and intracavitary markers to obtain a fusion contrast imaging result. This application links contrast images and intracavitary images through contrast markers and intracavitary markers, enabling intracavitary image information and contrast image information to correspond and be fused to obtain a fusion contrast imaging result, thereby overcoming the problem that traditional contrast images contain only a single type of information.

Systems and methods for simultaneous phase-contrast imaging and electron energy loss spectroscopy. The method and system for imaging a sample with charged particles include guiding charged particles toward the sample along a principal axis, and simultaneously detecting a first portion and a second portion of the charged particles transmitted through the sample using a first detector and a second detector, respectively. The second detector is positioned downstream of the first detector. Each of the transmitted charged particles exits the sample at an exit angle between the direction of the transmitted charged particle and the principal axis. The exit angle of the first portion of the transmitted charged particle overlaps with the exit angle of the second portion of the transmitted charged particle. In this way, complementary information, such as structural and compositional information, can be obtained simultaneously.

The present application provides a method for playing an ultrasound contrast imaging movie file, an ultrasound movie file playing method, and an ultrasound device. The method comprises: receiving a playback instruction for a movie file, wherein the movie file is dynamic data of an ultrasound image, the ultrasound image is formed according to an ultrasound echo, and the ultrasound echo is a sound wave signal returned after the probe of the ultrasound device sends an ultrasound wave to the target tissue; determining the imaging frame rate of the ultrasound image; determining the playback frame rate of the movie file according to the imaging frame rate, wherein the imaging frame rate is negatively correlated with the playback frame rate; and playing the movie file at the playback frame rate. When playing a movie file at a playback frame rate that is negatively correlated with the imaging frame rate, a movie file with a low frame rate plays more smoothly, and a movie file with a high frame rate plays more in line with the human eye's perception.

A system for analyzing biological components in a biological sample, wherein the system comprises a planar surface, and wherein the system is configured to perform a procedure comprising: (a) arranging a spatially connected biological sample adjacent to the planar surface, wherein: the spatially connected biological sample comprises a tissue sample, the tissue sample comprises a plurality of cells, the planar surface comprises glass, plastic, or a combination thereof, the planar surface further comprises a plurality of binding sites, the plurality of binding sites is arranged in a two-dimensional pattern on the planar surface, the planar surface comprises at least 10⁵ binding sites, each of the plurality of binding sites comprises a plurality of single-stranded oligonucleotides, and the plurality of single-stranded oligonucleotides is coupled to the planar surface.at least one subset of the plurality of single-stranded oligonucleotides comprises: (i) a binding sequence comprising a plurality of thymine bases configured to bind to poly-A sequences, (ii) a unique molecular identifier, (iii) a barcode associated with a position on the planar surface, and (iv) a sequencing primer, and each oligonucleotide of the subset of the plurality of single-stranded oligonucleotides comprises at least 50 nucleotides; (b) imaging at least a portion of the spatially linked biological sample, wherein the imaging comprises bright-field imaging, phase-contrast imaging, fluorescence imaging, or a combination thereof; (c) releasing nucleic acids from the spatially linked biological sample; and (d) capturing at least one subset of the nucleic acids on at least the subset of single-stranded oligonucleotides, thereby recovering the captured nucleic acids.the captured nucleic acids are immobilized on the flat surface.

The present invention relates to an X-ray multi-contrast image fusion characterization method based on unsupervised feature learning, and belongs to the field of deep learning and X-ray multi-contrast imaging technology. The method comprises: obtaining absorption, phase, and dark field contrast computed tomography images of X-ray grating imaging; constructing a generative adversarial network model based on unsupervised feature learning; training a generative adversarial network model based on unsupervised feature learning; using the trained model to fuse the absorption, phase, and dark field contrast computed tomography images to obtain a fused image, and using the fused image to characterize the inspected object. Compared with the existing X-ray grating multi-contrast imaging technology, the embodiment of the present invention can better utilize the advantage of X-ray grating differential phase contrast imaging that can produce three different contrast images at the same time, and perform fusion characterization on the three contrast images.

This invention provides a method for charged particle beam (CPB) phase contrast imaging. [Solution] In a CPB system, the phase contrast image is obtained by directing a sample-modulated CPB to the phase plate so that it has a diffraction plane displaced from the phase plate. Based on the interference fringes of the image, the lateral displacement of the CPB relative to the phase plate can be estimated and adjusted.

This invention belongs to the field of acoustic detection technology for partial discharge in power equipment, and relates to an array-type acoustic imaging partial discharge detection method and system. The method includes: establishing the correspondence between channel identifier sequences and array geometric parameters; dividing the array into subgroups according to a fixed subgrid and generating a synchronous sampling time sequence to acquire multi-channel pulse density modulation signals; demodulating and extracting the signals, bandpass filtering and pulse framing; constructing a forward-backward spatial smoothing covariance matrix and using minimum variance distortionless response beamforming to calculate the spatial spectrum to generate an acoustic image; and registering and superimposing the acoustic image with a visible light image to output the positioning result. The technical solution of this application achieves high-contrast imaging and stable positioning output through temporal and geometric consistency constraints, which can improve the consistency of on-site interpretation and meet the requirement of repeatable positioning under weak partial discharge ultrasonic conditions.

The invention discloses a magnetic resonance non-enhanced lower limb arteriovenous combined imaging method, which belongs to the technical field of medical imaging, and comprises the following steps: S1, judging acquisition times and carrying out first acquisition, S2, setting delay time of data acquisition, S3, configuring a rapid interruption steady state and carrying out data acquisition, S4, repeating the steps S1 to S3 until all regions finish a data collection process of the first acquisition, the method comprises the following steps of S1, carrying out first acquisition, S2, carrying out second acquisition, S5, switching to second acquisition, judging the number of acquisition times, and carrying out second acquisition, S6, carrying out data acquisition by using the same process as S2 and S3, S7, repeating the steps S5 and S6 until all regions complete data collection of the second acquisition, and S8, carrying out image reconstruction to obtain an arteriovenous separation image. By fusing the fast interruption steady-state sequence and the golden angle radial sampling track, lower limb artery and vein synchronous high-contrast imaging is achieved under the condition that electrocardio gating is not needed.

The embodiment of the invention discloses a super-resolution contrast imaging processing method and an ultrasonic imaging device, after a microbubble contrast agent is injected into a target tissue, a group of ultrasonic waves are generated to the target tissue through ultrasonic acquisition equipment, and ultrasonic data used for generating a super-resolution contrast image are obtained according to echo signals of the group of ultrasonic waves; but super-resolution imaging processing is not immediately carried out on the obtained ultrasonic data, but the group of ultrasonic data is stored in a data memory, and at the moment, the ultrasonic acquisition equipment can carry out ultrasonic acquisition on the target tissue again; therefore, according to the method provided by the embodiment of the invention, the ultrasonic data can be acquired for multiple times after the microbubble contrast agent is injected once, the problem that the ultrasonic data can only be acquired once during injection each time is solved, and the efficiency of acquiring the high-quality super-resolution contrast image in actual clinic is improved.

The application discloses a high-performance visible light-long-wave infrared two-light-in-one optical system, and mainly solves the problems of large volume and weight of a traditional independent visible light system and an infrared waveband optical system. The optical system comprises a main reflector, a spectral light splitting element, a visible light continuous zoom optical module and a long-wave infrared optical module. A light beam from a target object is reflected by the main reflector and reaches the spectral light splitting element, and is then divided into two paths, one of which is reflected into the visible light continuous zoom optical module, and the other is transmitted into the long-wave infrared optical module. The main reflector, the spectral light splitting element and the visible light continuous zoom optical module jointly form a visible light continuous zoom optical system and receive visible light in the light beam; and the main reflector, the spectral light splitting element and the long-wave infrared optical module jointly form a long-wave infrared optical system and receive long-wave infrared light in the light beam. The optical system can meet the requirements of long-distance high-sensitivity detection and medium-short-distance high-resolution high-contrast imaging of the target.

A portable and cost-effective programmable scanning diffuse speckle contrast imaging (PS-DSCI) technique enables noncontact, fast and high-density imaging of deep tissue blood flow, blood oxygenation, and tissue optical properties. PS-DSCI incorporates a digital micromirror device (DMD) for programmable fast scanning of near-infrared lights (e.g., line shape scanning) at different wavelengths over a large region of interest (ROI). A high-resolution 2D camera captures intensity images at each scanning source position. Novel image processing algorithms are created to define the pixel / detection areas at varied distances from the illumination center for capturing diffused photons from the tissue at varied depths. Spatial laser speckle contrasts are calculated in the defined detector regions and then converted to blood flow images at different depths. Line-shape scanning enables high temporal resolution to detect low-frequency oscillations (<0.1 Hz) across different brain regions, thus allowing for the reconstruction of brain functional connectivity maps.

The imaging apparatus configured to assess and quantify motion associated with an object and, in a specific case of an eye—retinal vascular anatomy and hemodynamics and generate substantially contrast-free maps of retinal blood flow over a wide field-of-view at up to 590 fps and under short exposure durations (>50 μs), is applicable for diagnosis, study, and management of neurodegenerative conditions (i.e. mild cognitive impairment and Alzheimer's disease) and systemic cardiovascular diseases (i.e. athero- and arteriosclerosis, coronary artery occlusion, and hypertension). The apparatus employs a) a set of apertures substantially blocking light, delivered from a source of light to an illumination arm of the apparatus, from impinging onto an axial point of the front surface of the lens of the illumination arm, and b) polarization gating between the illumination and light-collecting arms of the apparatus. In one implementation, the apparatus is configured to allow for irradiation of the object with an optical field a degree of coherence and / or spectral content of which are varied delivered through the same optical train including the set of apertures.

The present invention belongs to the field of micro-nano processing technology, specifically a method for overlaying a large-area light-blocking area based on pattern assistance. The present invention introduces an auxiliary pattern around the existing structure, so that the auxiliary pattern and the top layer of photoresist form a protective barrier together, effectively covering the side of the structure, and overlaying the large-area light-blocking area onto the working area with poor photoresist wettability, ensuring that the working area of ​​the hard X-ray photon screen is not damaged during the processing, thereby ensuring the high performance and stability of the final product; specifically, it includes the processing of the working area, auxiliary pattern and light-blocking area of ​​the device, and is completed on a thin film window; its process flow includes photolithography, metallization, debonding, overlaying, metallization and debonding. The method of the present invention has the advantages of improving overlay accuracy, saving electron beam lithography time, shortening process time, etc.; it is suitable for hard X-ray high-contrast imaging of biological cells, organic materials and dielectric materials.

The utility model discloses a near-infrared lymph node detection system. The detection system comprises an infrared imaging system, the infrared imaging system comprises an excitation light source, a beam expanding element, a light path forwarding device, a light filtering device and a short-wave infrared sensor which are arranged along a light path, and an image processing and displaying device which is in communication connection with the short-wave infrared sensor; wherein the excitation light source is a continuous spectrum light source or a wavelength continuously adjustable light source. According to the utility model, based on a near infrared spectrum imaging technology known as a biological transparent window, image processing is carried out in combination with a model algorithm, and an innovative solution is provided for lymph node detection; according to the system, the low tissue scattering characteristic of a near-infrared window and the absorption peak difference characteristic of main biological components in a near-infrared spectrum are utilized, and high-contrast imaging of lymph nodes and surrounding adipose tissues is achieved without a tracer agent. The detection system provided by the utility model can provide real-time guidance and tracking for related operations.

The blood flow distribution determination unit 111 analyzes a first three-d imensional time-series image including an analysis target site of a subject imaged using phase-contrast imaging by an MRI (Magnetic Resonance Imaging) device to iden tify the blood flow velocity distribution of the analysis target site. The shape d etermination unit 112 analyzes a second three-dimensional time-series image indica ting the anatomy of the subject imaged using a method different from phase-contras t imaging to identify the shape of the analysis target site. The image generation unit 113 generates a fused image by overlaying the first three-dimensional time-se ries image and the second three-dimensional time-series image. The index generatio n unit 114 generates an index related to blood flow flowing inside the shape based on the blood flow velocity distribution and the shape in the fused image. The outp ut unit 115 associates the shape with the index and outputs them. This reduces the burden on subjects in blood flow measurements.

The application relates to the technical field of medical devices, in particular to a skin ultrasound contrast-based axillary sentinel lymph node puncture guiding method. The core of the method is as follows: after injecting an ultrasound contrast agent with a specific particle size through the skin, a preset low-mechanical-index high-frame-rate double-amplitude contrast imaging mode is adopted to dynamically track lymph drainage and sentinel lymph node development, and the enhancement characteristics are recorded; then, under the guidance of multimodal imaging which is fused with real-time contrast, elastic imaging and color Doppler, the target lymph node is accurately punctured and biopsied, and a tissue sample is obtained for pathological analysis. The application realizes integrated operation from sensitive development of the sentinel lymph node, function evaluation to accurate puncture, and provides a non-radiation high-precision puncture guiding method for accurate evaluation of the axillary lymph node state of breast cancer patients before operation.

This invention relates to the field of high-contrast imaging with optical synthetic aperture, specifically to a method, medium, and device for precise detection of co-phase errors using non-coaxial beam-combining zero-elimination interferometry. This invention directly utilizes the non-coaxial zero-elimination interferometry signal for error inversion, eliminating the need for additional optical components. Furthermore, the algorithm does not require iteration, resulting in a high detection frequency, making it suitable for co-phase applications with high real-time requirements. The co-phase scheme of this invention can simultaneously demodulate tilt and piston errors with high precision using only the zero-elimination interferometry signal without adding additional optical components. This invention also demodulates relative tilt and piston errors using two-dimensional discrete Fourier transform, exhibiting strong anti-noise interference characteristics and making it suitable for co-phase applications with low signal-to-noise ratios.

The application discloses a kind of quantitative channel contrast imaging methods based on scanning electron microscope, electronic equipment and medium, comprising: the polycrystalline sample is placed into scanning electron microscope system, determines ROI, obtains crystal data;Adjust the state of polycrystalline sample, obtain the cross-correlation diagram of backscattered electron image and diffraction contrast value image, so that backscattered electron beam scanning area and ROI coincide;In ROI, optional one position, calculate ECP under the current electron beam energy;Determine target orientation on ECP, determine the optimal path of rotating polycrystalline sample to target orientation;Get backscattered electron image before and after rotation and cross-correlation, move polycrystalline sample so that backscattered electron beam scanning area before and after rotation coincide;Adjust scanning electron microscope system by the above steps, collect a series of backscattered electron images of ROI.The application can realize the characterization and analysis of block sample dislocation, nanotwin, stacking fault and other crystal defects by scanning electron microscope.

Disclosed are a method, device, and system for X-ray CT contrast imaging using magnetic nanoparticles. The method includes: rotating a target object containing magnetic nanoparticles as contrast agent for one circle relative to X-rays, recording multiple consecutive transmission projection images of the target object at all angles; for multiple transmission projection images at each angle, after conducting image post-processing operations, performing inverse projection transform on magnetic nanoparticle imaging projection images at all angles to obtain a tomographic imaging result. The image post-processing operation includes: time-frequency transform: converting the third dimension of the three-dimensional time domain matrix to frequency domain to obtain a three-dimensional frequency domain matrix; feature extraction: selecting a two-dimensional matrix with frequency of kf along the third dimension of the three-dimensional frequency domain image matrix; k is a positive integer; f is the frequency of the excitation magnetic field.

The present application provides an ultrasound contrast imaging method, an ultrasound imaging device, and a storage medium. The method comprises: stimulating an ultrasound probe based on multiple ultrasound pulses to transmit ultrasound waves toward a target medium containing a contrast agent, receiving echoes of the ultrasound waves, and acquiring multiple sets of ultrasound echo data based on the echoes of the ultrasound waves; wherein at least one of the amplitude, phase, and frequency of the multiple ultrasound pulses is different; extracting contrast microbubble signals from the multiple sets of ultrasound echo data to obtain data to be processed; performing singular value decomposition filtering on the processed data to obtain processed data; and obtaining a contrast image based on the processed data. The solution of the present application performs singular value decomposition filtering on the ultrasound echo data containing microbubble signals, and processes the data used for contrast imaging in the non-frequency domain. This can avoid the problem of frequency band overlap that occurs during frequency domain processing, thereby further improving the signal-to-noise ratio and contrast-tissue residual ratio of the contrast image.

The invention provides a surgical imaging system with navigation and a precision correction method thereof, and the method comprises the steps: tracking the position of a positioning mark through a navigation module, and obtaining the calculation position of an imaging module in combination with a calibration relation; generating a virtual reference frame under the visual angle of the imaging module according to the calculation position of the imaging module and the position of the reference frame tracked by the navigation module; and correcting the calibration relation according to the deviation between the virtual reference frame under the visual angle of the imaging module and the actually seen reference frame. According to the method, the position of the imaging module is determined by tracking the positioning mark in combination with the pre-calibrated conversion relation, the position of the reference frame is tracked, then the virtual reference frame image under the visual angle of the imaging module is obtained through processing, and the real reference frame is obtained by comparing the virtual reference frame under the visual angle of the imaging module with the real reference frame. And the error of the calibration relation can be intuitively judged and corrected.