The invention discloses a cream for firming, improving and beautifying breasts and a preparation method thereof. The cream comprises the following components in parts by weight: propylene glycol, ethylhexyl palmitate, petrolatum, mineral oil, isohexadecane, glycerin, grape seed oil, polydimethylsiloxane, egg yolk oil, phenoxyethanol, methylparaben, propyl hydroxybenzoate, deuterium-containing water, glyceryl stearate, xanthan gum, cetostearyl alcohol, methyl glucose sesquistearate, PEG-20 methyl glucose sesquistearate, allantoin, radix puerariae extract, vanillyl butyl ether, lavender oil, sandalwood seed oil, cananga odorata oil, rose flower oil, 1,2-hexanediol, caprylhydroxamic acid, pseudo-ginseng extract and danshen root extract. The cream for firming, improving and beautifying the breasts disclosed by the invention integrates the effects of moisturizing, restoring elasticity of local tissues, promoting blood circulation to remove blood stasis with a plurality of plant extracts, firming and improving the breasts and restoring saturation of honeycomb tissue cells of the breasts, so that the effect on the whole breasts is remarkable.