752 results about "Colostrum" patented technology

The present invention relates to a foodstuff which comprises colostrum, a probiotic and a prebiotic. The triple combination of colostrum, a probiotic and a prebiotic is particularly beneficial for the gastrointestinal tract and health of animals.

The present invention relates to a novel method for the isolation or purification of immunoglobulins (a special class of proteins) from a solution containing immunoglobulins, e.g. hybridoma cell culture supernatants, animal plasma or sera, or colostrum. The method includes the use of a minimum of salts, such as lyotropic salts, in the binding process and preferably also the use of small amounts of organic solvents in the elution process. The solid phase matrices, preferably epichlorohydrin activiated agarose matricees, are functionalised with mono- or bicyclic aromatic or heteroaromatic ligands (molecular weight: at the most 500 Dalton) which, preferably, comprises an acidic substituent, e.g. a carboxylic acid. The matrices utilised show excellent properties in a “Standard Immunoglobulin Binding Test” and in a “Monoclonal Antibody Array Binding Test” with respect to binding efficiency and purity, and are stable in 1M NaOH.

A topical composition for treating a cutaneous wound includes whole colostrum or one or more growth factors, as well as a base by which the whole colostrum or one or more growth factors are carried. The topical composition may also include, without limitation, immunomodulators, lactoferrin, enzymes, vitamins, minerals, amino acids, or combinations thereof. Other components may also be included in the topical composition, including, but not limited to, antiseptics, antimicrobial agents, and anesthetics. When applied to a wound, the bioactive topical composition promotes healing of the treated wound.

The present invention provides a method and composition for the treatment and / or prevention of infection, said method comprising orally administering a composition to a mammal, said composition comprising a galactose containing indigestible oligosaccharide and immunoglobulin from the milk or colostrum of hyperimmunized cows.

Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, colostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, colostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and / or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.

The invention provides a calcium supplementing and calcium locking health care food. The calcium supplementing and calcium locking health care food comprises calcium, colostrum basic protein, chondroitin sulfate, D-glucosamine, vitamin D, casein phosphopeptides and the like, wherein the colostrum basic protein is obtained by degreasing, separating, concentrating, removing casein, alpha-lactoalbumin, beta-lactoglobulin and substances with molecular weights of more than 30 kDa and less than 1 kDa and drying at a low temperature; the biggest difference between the calcium supplementing and calcium locking health care food prepared by the method provided by the invention and the prior art is that the capacity of the bone tissue in actively absorbing osteoblast nutrition like calcium, ossein and the like can be effectively improved and effects of activating osteoblasts and inhibiting osteoclast activity to enhance bone mineral density and length and promote the health of the bone are obtained. The calcium supplementing and calcium locking health care food provided by the invention, which is a latest generation of domestic osteoarthrosis rehabilitation product, obtains breakthrough in the calcium supplementing effect, can be also used for helping the bone to preferably absorb the calcium in the food, has no toxic and side effect after being taken for a long time.

A two-phase milk substitute instead of foremilk and milk for calf is prepared from the vegetative protein (soybean protein), whey powder, water-soluble fat, digestion assistant, minerals and vitamins.

The invention provides a formula and a corresponding preparation method of a probiotics solid beverage with probiotics micro-capsule powder, prebiotics, bovine colostrum powder and yeast beta-glucan as raw materials. By means of special matching and selection of specific bacteria in probiotics micro-capsule powder, the prepared solid beverage is favorable for improvement of the gastrointestinal tract of a human body and is further favorable for improvement of immunity of a human body.

A method for feeding young white goats relates to the technical field of breeding in animal husbandry. The method for feeding the young goats in different periods after birth includes: allowing the 1-3 days aged young goats to drink colostrum as soon as possible; guaranteeing uniform sucking time of 4-7 days aged young goats to prevent diseases of 'pneumonia, enterogastritis, stomatitis and lamp dysentery'; training the 8-20 days aged young goats to eat grasses; allowing the 21-30 days aged goats to graze with ewes; allowing the 1-4 months aged young goats to feed mainly on their own; weaning the young goats when the young goats are aged from 42 days to 4 months; and grouping the weaned young goats according to sex, body weight and physique state. The method is applicable to young mutton goats which are fed by and follow the ewes for farmers or farms in agricultural areas farming Huanghuai white goats. The white goats bred by the method are high in survival rate and grow fast, breeding cycle of the white goats can be shortened, and quality of marketable goats is fine.

Nutritional compositions containing selenium, colostrum and whey are described. The compositions may be mixed with mammalian food to increase the concentration of glutathione in the mammalian body thereby to enhance the response of the mammal's immune system to infection.

Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and / or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.

The present invention relates to a foodstuff which comprises colostrum, a probiotic and a prebiotic.The triple combination of colostrum, a probiotic and a prebiotic is particularly beneficial for the gastrointestinal tract and health of animals.

A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.

The present invention relates to nutritional food and drugs, particularly to a composition with characteristics of liver tonifying, kidney nourishing, intestine and stomach function conditioning, constipation improving, intestinal flora disorder improving, immunity regulation, calcium supplement, nutrient absorption promotion and no side effect. The composition comprises, by weight, 10-30 parts of cistanche deserticola or songaria cynomorium herb and 30-98 parts of one or a plurality of materials selected from probiotic bacteria, milk calcium, tartarian buckwheat and animal colostrum.

A method for prophylactically treating a gastrointestinal disorder or skin ailment in a mammal through the administration of an enhanced bioactive agent composition comprising a bioactive agent and at least one of a soy product, licorice product, or sodium bicarbonate (depending upon the indication to be treated) is provided according to the invention. The bioactive agent preferably is bovine colostrum. The effective amount of enhanced bioactive agent composition to be used will depend upon such factors as the age and weight of the mammal, the bioactivity level of the bioactive agent, the gastrointestinal disorder or skin ailment at issue, and whether treatment of existing symptoms of the gastrointestinal disorder or skin ailment, or prevention of the onset of such symptoms is desired. A medicament comprising an enhanced bioactive agent composition for prophylactically treating a gastrointestinal disorder or skin ailment in a mammal is also provided according to the invention.

The invention discloses infant formula goat milk powder and a preparation method thereof. Alpha-lactalbumin and hydrolytic lactalbumin peptide, malt sugar (corn syrup), glucose, pure colostrum powder, lactoferrin, living bifidobacterium and the like are added in the infant formula goat milk powder. The method comprises the steps of: obtaining goat milk, performing pasteurization (85 DEG C), cutting material mixing tanks with high speed (the material in the tank includes malt sugar, glucose, decavitamin, mineral nutrient, hydrolytic lactalbumin peptide and plant oil), using a homogenizer, performing pasteurization, vacuum concentration and spray drying, cooling a fluid bed (adding the lactoferrin, the pure colostrum powder IgG and the plant oil), mixing the added materials (adding the lactoferrin, the pure colostrum powder IgG and the living bifidobacterium), and canning. The infant formula goat milk powder is easy to digest and absorb, and muting sensitive; and the formula powder is more humanized, and can enhance organism immunity.

The invention relates to sterile bovine colostrum whey with natural immunocompetence, and a preparation method and an application thereof. The preparation method comprises the steps of centrifuging bovine colostrum, removing fat to obtain defatted bovine colostrum, settling casein in the defatted bovine colostrum by an isoelectric point method or a chymosin method, obtaining whey liquid, or dissolving bovine colostrum whey powder to obtain the whey liquid, pre-filtering with a hollow fiber membrane or a ceramic membrane, removing the residual fat, casein and most thalli in the whey, conducting filtration sterilization with a polytetrafluoroethylene membrane filter, filling under a sterile condition, and obtaining the sterile bovine colostrum whey. The sterile bovine colostrum whey is degermed by a polytetrafluoroethylene degerming membrane based on pre-filtering, the handling capacity of feed liquid is increased, the service life of the membrane is prolonged, the membrane cost is saved, and the sterile bovine colostrum whey is suitable for industrial production. The content of immunoglobulin in the obtained whey is high; sterile requirements can be met; and the whey can directly serve as an immunoglobulin-rich whey product, and can also be added to beverages such as milk and fruit juice to be made into functional beverages.

A composition and method for immunization of mammals, containing antibodies from the eggs / egg yolks of chickens, or other suitable avian source, hyperimmunized against a selected pathogen(s) or immunogens, and a quantity of non-specific mammalian antibodies, such as those from commercial colostrum or serum products, which are combined to produce a composition that provides protection against the selected pathogen. Applications include viral, bacterial and parasitic infections.

The present invention relates to products and methods for preventing, ameliorating and / or treating infections and other diseases. In one aspect, the products of the present invention relates to compositions comprising germ free colostrum. In another aspect, the products of the present invention relates to compositions comprising synthetically multimerised immunoglobulins. In a third aspect, the products of the present invention relates to compositions comprising germ free colostrum enriched with synthetically multimerised immunoglobulins. The invention also relates to use of said compositions as a pharmaceutical e.g. for prophylactic or ameliorating treatment of infections and other diseases. In addition the invention comprises methods for production of said compositions.

The invention provides a nimodipine lipid microsphere injection, which is prepared from the following components in percentage by weight: 0.08 percent of nimodipine, 0.5 to 2.3 percent of lecithin for injection, 2 to 8 percent of soybean oil for injection, 2 to 8 percent of medium chain fatty acid for injection, 1 to 3 percent of glycerin, 0.1 to 0.2 percent of tween-80, 0.03 to 0.05 percent of sodium oleic acid, and the balance being water for injection. The preparation method comprises steps of preparation of an oil phase, preparation of water phase, preparation of colostrum, homogenization and canning. In the nimodipine lipid microsphere injection, the soybean oil for injection and the medium chain fatty acid for injection are used to prepare the oil phase, the nimodipine is a fat soluble drug and can be better dissolved in the oil phase, the lipid microsphere in which the soybean oil for injection is the main component has solvent characteristics, is non-toxic, and can guide the fat soluble drugs to be dissolved in emulsion particles and perform the metabolism along with lipid oil drops and slowly release, thereby maintaining the effective blood concentration, lowering toxic and side effects of the drugs, increasing the solubility and stability of the nimodipine drug, improving the drug-loading rate and reducing the hydrolysis of the drugs.

A dietary supplement for mammalian consumption, and particularly human consumption, for the purpose of stimulating the immune system, inhibiting infection and increasing tissue repair and healing. Comprising colostrum, lactoferrin, and with modified citrus pectin as an optional component, the dietary supplement is administered in ‘mucosal delivery format’: a dosage form that promotes effective absorption through the lining of the oral cavity.

The invention relates to a lactoferrin antibacterial peptide, the preparation method and the application thereof. The method utilizes the lactoferrin and the enzyme preparation in bovine colostrum to prepare the lactoferrin antibacterial peptide zymolyte through enzymic hydrolysis, and subjects the zymolyte to macroporous absorption static or dynamic desalination, gel filtration chromatography, half-preparation high efficiency liquid chromatography and analysis-type high efficiency liquid chromatography for separation and purification to obtain a pure lactoferrin antibacterial peptide product. The product has high-efficient and broad-spectrum antibacterial capability, thereby having broad prospects for application in food, feed and medical fields.

The invention discloses aprobiotic solid beverage for infants. The probioticsolid beverage comprises components in percentage by weight as follows: 15-25% of bifidobacterium powder, 15-25% of lactobacillus rhamnosus powder, 10-30% of rice protein powder, 10-20% of bovine colostrum powder, 5-15% of maltodextrin, 5-10% of fructo-oligosaccharide and 5-10% of galactooligosaccharide. The probioticsolid beverage is natural in component, scientific in formula, balanced in nutrition, convenient to drink, free of caking, good in dissolving ability and unique in taste and has effects of improving intestinal tracts of the infants, improving digestion and enhancing the immunity.

The invention relates to a traditional Chinese medicine preparation for promoting lactation of pregnant sows, which is composed of astragalus, angelica, Codonopsis pilosula, Rhizoma Chuanxiong, Wang Buliuxing, Passepartout, motherwort and Cyperus cyperi. Significantly increase the serum prolactin (PRL) and growth hormone (GH) levels of lactating sows, promote the lactation performance of sows; increase the protein content in colostrum, promote the growth and development of sucking piglets; increase the serum complement C3 and immunoglobulin of sucking piglets (IgG, IgM, IgA) content and superoxidase (SOD) activity, reduce malondialdehyde (MDA) content, improve immune function and antioxidant function of suckling piglets.

The present invention relates to a method for inhibiting bacterial colonisation of mucous epithelium in a biological system. The method includes the step of administering to the biological system an effective amount of a mucolytic agent and one or more of colostrum, hyperimmune milk, or a component of colostrum and / or hyperimmune milk that is capable of inhibiting bacterial colonisation in combination with the mucolytic agent.

The invention discloses liquid formula milk special for weak piglets. The liquid formula milk special for weak piglets is characterized by being made from, formula milk powder and purified water by mixing according to a ratio of 1:3.6-4.4. The liquid formula milk special for weak piglets comprises, by weight percent, 30%-50% of bovine colostrum (in dry powder), 10%-20% of skim milk powder, 10%-20% of lactose, 10%-20% of whey protein concentrate, 2%-5% of mixture of fish oil, coconut oil and emulsifier, 1%-3% of probiotics, 0.5%-1% of carnitine, 0.2%-0.5% of arginine, 0.1%-0.3% of vitamin E, 0.1%-0.2% of yeast polysaccharide, 0.1%-0.2% of lysosome, 0.5%-1% of suckling pig multi-vitamins, and 0.5%-1% of suckling pig trace element composite. The liquid formula milk special for weak piglets has the effects of improving immunity, enhancing stress resistance and disease resistance, promoting digestion, preventing piglet diarrhea, promoting growth and the like. Immunity and growth ability ofthe weak piglets fed with the liquid formula milk special for weak piglets can be improved effectively, and survival rate of the weak piglets can be increased.

The invention provides a method for separating and purifying immunoglobulin A, immunoglobulin G and lactoferrin from bovine colostrum in an industrializing way, which comprises the following steps of: (1) degreasing the bovine colostrum and separating casein to prepare whey; (2) after micro-filtering the whey for degerming, carrying out cation exchange chromatography to obtain a first fast flow liquid, eluting a chromatographic column to obtain eluent, ultra-filtering, concentrating and desalting the eluent by using a first ceramic membrane, and freezing and drying to obtain the lactoferrin; (3) carrying out anion exchange chromatography on the first fast flow liquid to obtain a second fast flow liquid, eluting the chromatographic column to obtain eluent, ultra-filtering, concentrating and desalting the eluent by using a second ceramic membrane, and freezing and drying to obtain the immunoglobulin A; and (4) ultra-filtering, concentrating and desalting the second fast flow liquid by using a third ceramic membrane, and obtaining the immunoglobulin G by using low-temperature spray drying. By utilizing the method, the immunoglobulin A, the immunoglobulin G and the lactoferrin can be separated and purified from the bovine colostrumin efficiently and continuously in the industrializing way.

The invention discloses a milk calcium formula nutritional powder, which comprises the following components in percentage by weight: 10-20% of milk calcium powder, 18-25% of fructo-oligosaccharide, 1-5% of casein phosphopeptide, 1-5% of colostrum basic protein and the balance whole milk powder. In the formula, the milk calcium powder is added, and a 'CPP-FOS-CBP' triple progressive calcium absorption formula is used. Compared with common inorganic or organic calcium sources, the milk calcium formula nutritional powder is safer and has higher absorption rate.

A composition including colostrum or a colostrum-derived product and hyperimmune milk (HIM) or a hyperimmune milk-derived product, in amounts sufficient to provide a combined spectrum of pathogen-binding activity against a broad-spectrum of pathogenic organisms.