136 results about "Colostrum" patented technology

The invention relates to the technical field of microorganisms, in particular to application of streptococcus non-lactolyticus GX-7 and a complex microbial inoculant thereof in sugarcane leaf silage, the strain GX-7 is separated from healthy pig manure by a research group, and through detection, the strain has good cholate resistance and is suitable for surviving in intestinal tracts, and the strain GX-7 has good cholate resistance and is suitable for being used as a feed additive. The antibacterial effect on pseudomonas fluorescens, listeria monocytogenes, salmonella choleraesuis and shigella flexneri is achieved; the strain has a good fermentation capability on sugarcane leaves, and the sugarcane leaves are inoculated with a complex microbial inoculant prepared from streptococcus non-lactolyticus GX-7 and streptococcus non-lactolyticus GX-2, so that a synergistic fermentation effect can be achieved; after the silage prepared from the complex microbial inoculant is fed to female buffalo in the gestation period, it is found that the silage can effectively increase the content of milk protein, milk total solids and milk non-fat solids in colostrum of the female buffalo and relieve diarrhea of the female buffalo, and the silage is safe and good.

The invention provides a polypeptide, and the sequence of the polypeptide is AEDVGDVAFVKNDT. The polypeptide provided by the invention can inhibit the human respiratory syncytial virus surface protein F so as to inhibit the fusion of the human respiratory syncytial virus surface protein F and a host cell membrane. The invention also provides the sheep colostrum. The sheep colostrum comprises the polypeptide with the antiviral function, so that the sheep colostrum is helpful for old people with relatively weak resistance to resist infection of human respiratory syncytial viruses and promotes repair of respiratory mucosa. The invention also provides a preparation method of the sheep colostrum. The preparation method is simple and can be used for industrial production. The invention also provides a preparation method of the polypeptide.

The invention provides modified milk powder capable of promoting bone health as well as a preparation method and application of the modified milk powder. The total protein content of the modified milk powder is 17-35 g / 100 g, the fat content of the modified milk powder is 1-32 g / 100 g, and the calcium content of the modified milk powder is 0.8-2.1 g / 100 g. Moreover, the modified milk powder contains bovine coloctrum and lactoferrin, the mass ratio of the bovine coloctrum to the lactoferrin is (5-100): 1 on the basis of the dry matter content, and the content of the lactoferrin in the modified milk powder is 2-400 mg / 100 g. The bovine colostrum and the lactoferrin are combined for preparing the milk powder, have a synergistic effect on promoting osteoblasts and inhibiting osteoclast proliferation, and are beneficial to bone health.

The invention discloses an enzymolysis preparation method of high-immunocompetence bovine coloctrum peptide, active peptide and application thereof, and belongs to the field of biotechnology and functional foods.The enzymolysis preparation method is characterized by comprising the steps that bovine coloctrum is degreased, trehalose is added into obtained supernate, first stirring is conducted, and first mixed liquid is obtained; wherein the supernate comprises whey protein and Ig; adding medium protease into the first mixed solution for hydrolysis to obtain enzymatic hydrolysate; wherein the enzymatic hydrolysate comprises a mixture of bovine colostrum hydrolyzed peptides, the Ig activity retention rate is larger than or equal to 90% through the targeted protection and directional enzymolysis technology, the beta-lactoglobulin peptide with the synergistic immune enhancement effect is obtained, the Ig and small molecule peptides in the product have the synergistic effect, the body immune regulation capacity and the intestinal immune function are remarkably improved, the immunity of the human body is improved, and the immunity of the human body is improved. The method can be widely applied to the fields of infant formulas, postoperative nutrition, functional drinks and the like.

The invention discloses sheep colostrum immune globulin powder and a preparation process thereof, and relates to the technical field of protein powder. The sheep colostrum immune globulin powder is prepared from the following components in parts by weight: 200 to 250 parts of a sheep colostrum raw material, 350 to 400 parts of whole milk powder, 330 to 370 parts of skimmed milk powder, 30 to 50 parts of prebiotics, 8 to 12 parts of acerola cherry powder, 0.8 to 1.2 parts of lactoferrin, 0.4 to 0.6 part of N-acetylneuraminic acid and 0.3 to 0.5 part of probiotics. Diversified nutritional requirements of a human body are fully considered, various nutritional ingredients are matched with one another and have a synergistic effect, the nutritional ingredients can be better absorbed and utilized by the human body, comprehensive nutritional support is provided for consumers, and the requirements of daily nutritional supplement, physique enhancement, immunity improvement and the like are met.

The invention discloses a method for preparing high-activity bovine colostrum immune globulin through combination of multistage membrane filtration and ion exchange resin adsorption, and belongs to the technical field of bovine colostrum powder processing. According to the preparation method of the bovine coloctrum immune globulin, specifically, acidizing precipitation, ultrafiltration and nanofiltration separation, ion exchange resin selective adsorption and other means are adopted for pretreated bovine coloctrum for cooperation, so that the extraction rate and purity of the immune globulin are remarkably improved; meanwhile, active ingredients such as micromolecular growth factors and amino acid in the bovine coloctrum are effectively reserved, so that the final product is rich in high-activity immune globulin, other important nutritional ingredients in the bovine coloctrum are reserved, and the overall nutritional value and market competitiveness of the product are improved.

The invention provides a bovine colostrum probiotic compound preparation as well as a preparation method and application thereof. The compound preparation provided by the invention comprises the bovine colostrum powder subjected to activity protection and the compound probiotics, and the bovine colostrum powder subjected to activity protection is obtained by adopting a microcapsule double-layer embedding and freeze-drying technology, so that the gastric acid retention rate (2h) of immune globulin in the bovine colostrum powder is greater than or equal to 90%, and IgG contained in the bovine colostrum powder is ensured to be efficiently delivered to intestinal tracts to play an immune regulation role. Wherein the compound probiotics comprise four stages of functional echeles formed by more than or equal to 6 strains, and the four stages of functional echeles comprise colon colonization major flora, gastric acid-resistant pioneer flora, antibacterial peptide secretion auxiliary flora and inflammation regulation backup flora. Through cooperation of the components in the compound preparation, the compound preparation has excellent immune enhancement and metabolic regulation functions.

The application discloses a preparation method of an immune protein extract of colostrum with tumor inhibition efficacy, and comprises the following steps: (1) raw material selection; (2) flocculation of casein; (3) sugar removal; (4) ultrafiltration membrane filtration; (5) directional hydrolysis; (6) cation exchange resin adsorption; (7) desalination; and (8) freeze drying. The extract of the application is rich in hydrophobic amino acid and alkaline amino acid hydrolysis fragments of the immune protein of colostrum, and has stronger antioxidant, immune enhancement and tumor inhibition activities. Different from common immune proteins of colostrum, the extract plays the anti-tumor activity as a result of the combined action of its double effects of immune enhancement and tumor cell growth inhibition.

The application discloses an Akkermansia muciniphila branched-chain amino acid metabolism gene nifJ and application thereof in colostrum IgA synthesis, and belongs to the technical field of genetic engineering. The application finds through in-vivo and in-vitro tests that the nifJ is a branched-chain amino acid metabolism gene of the Akkermansia muciniphila, regulates the metabolism process from branched-chain amino acids to branched-chain short-chain fatty acids, and plays a key role in the synthesis of maternal colostrum IgA. The research result of the application is expected to clarify the interaction relationship between the metabolic function of the Akkermansia muciniphila and a host, and reveal the action mechanism of the Akkermansia muciniphila in regulating the synthesis of maternal colostrum IgA, thereby providing a theoretical basis for improving the maternal colostrum IgA and further improving the maternal reproductive performance.

This invention provides a bovine colostrum IgG nutritional supplement gummies and their preparation method, belonging to the field of functional food technology. The bovine colostrum IgG nutritional supplement gummies of this invention, through precise formulation of specific components, effectively improve the dispersion uniformity of whole-fat bovine colostrum freeze-dried powder in the gummy base, significantly retaining the activity of immunoglobulin G, giving the product a stable texture and good taste; further, combined with a special process adapted to the formula, high yield and high raw material utilization are achieved in industrial production. This product combines immune nutritional supplementation with convenient consumption, making it suitable for people of all ages and possessing good market application prospects.

This invention relates to the field of pet care product technology, and discloses a pet oral care spray and its preparation method. The preparation method employs a low-temperature gradient stepwise dissolution process: glucose oxidase is pre-dissolved at low temperature to obtain pre-solution A; bovine colostrum powder and lactoferrin are dissolved at low temperature to obtain protein pre-solution B; honey, folic acid, and vitamin D3 are dissolved at room temperature to obtain excipient pre-solution C; lysozyme is added to protein pre-solution B and stirred to dissolve; then pre-solution A and excipient pre-solution C are combined sequentially, the pH is adjusted, and purified water is added to make up the volume; the mixture is filtered through a microporous membrane for sterilization, and then filled and sealed under inert gas protection. This preparation method effectively protects the biological activity of each active protein and enzyme, achieving a long shelf life without the need for additional chemical preservatives. The resulting spray does not contain irritating ingredients such as alcohol and menthol, and is suitable for improving stomatitis, inhibiting plaque and tartar, and alleviating halitosis in pets of all ages and breeds.

The invention relates to the technical field of natural product extraction and bionic preparations, and provides a method for extracting curcuma oil from fresh turmeric, a curcuma oil microcapsule and application. The method comprises the following steps: S11, adding pretreated fresh turmeric into an extraction solution, and shearing and crushing; s21, adjusting the pH value of the extracting solution, adding a compound enzyme system, and then carrying out ultrasonic enzymolysis; s31, adjusting the pH value of the enzymatic hydrolysate, and then inactivating and filtering to obtain a first filtrate and filter residues; s41, adding a density gradient medium into the first filtrate, then carrying out low-temperature centrifugal separation, collecting upper-layer cream, and resuspending to obtain primary emulsion containing curcuma oil; s51, adding a surfactant into the primary emulsion, adjusting the pH value, and filtering to obtain a second filtrate; and S61, centrifuging the second filtrate at low temperature, collecting the upper-layer cream, and resuspending to obtain the curcuma oil emulsion. The curcuma oil obtained by the invention has the advantages of high solubility, high stability, high bioavailability and the like.

The utility model discloses colostrum pasteurization machine, its technical scheme main points are: including: the placement box, the inside movable installation of placement box has the protective cover, and the bottom surface of protective cover has established two placement grooves, ultraviolet disinfection lamp, ultraviolet disinfection lamp fixedly connected in the inside of placement groove, heating component, heating component sets up in the inside of placement box, when the inside of placement box is in to the colostrum pasteurization machine disinfection after, at this time staff through using clean water to clean the inside of placement box, to this avoid colostrum residual liquid to adhere to the inner wall of placement box, when the inside of placement box is cleaned, start ultraviolet disinfection lamp again, so that ultraviolet disinfection lamp can carry out sterilization and disinfection to the microorganism and bacteria of the inside of placement box, avoid the microorganism and bacteria in clean water to adhere to the inside of placement box, influence subsequent pasteurization effect and nutrient composition, when the rotating rod drives several stirring vane to rotate, at this time several stirring vane can even mix the colostrum in the inside of placement box.

A composition and method for therapeutic or prophylactic treatment of mammals includes a mixture of IgY antibodies derived from one or more eggs laid by one or more avian species, wherein each of the one or more avian species have been vaccinated with one or more of the plurality of antigens. The mixture of IgY antibodies can be combined with a protective material that includes colostrum. In some embodiments the composition can also include IgA and IgM antibodies.

The invention relates to the technical field of sports nutrition food, in particular to a product capable of providing muscle nutrition support and a preparation method thereof. The method sequentially comprises the following steps: (1) premixing concentrated / separated / hydrolyzed whey protein, bovine colostrum powder, alpha-lactalbumin, calcium silicate and compound sweet system dry powder at the temperature of less than or equal to 25 DEG C; (2) intermittently spraying the aqueous phase bonding liquid into a multi-section fluidized bed under the conditions that the temperature is 35-40 DEG C and the pressure is 0.3-0.5 MPa, and synchronously introducing supercritical CO2 under the pressure of 6-8 MPa and the temperature is 35-40 DEG C to realize pulse atomization and instantaneous foaming, so as to obtain wet particles with the true porosity of more than or equal to 60% and the water content of less than or equal to 8%; (3) step pressure reduction and 40-45 DEG C hot air drying until the water content is less than or equal to 4%; and (4) carrying out two-stage vibration classification, and recycling 180-300 microns of main materials. The method has the characteristics of low-temperature keep-alive, open pore structure and excellent flow instant solubility, and is suitable for large-scale production.

The present invention provides a method of feeding a ruminant animal, preferably a pregnant ruminant animal, using a phytogenic composition. By feeding the composition pre-partum, the colostrum yield may be increased and colostrum quality is improved. Moreover, milk yield and milk fat percentage may be increased during lactation phase of the ruminant animal.

The invention discloses a primer pair of an SNP (Single Nucleotide Polymorphism) molecular marker related to the concentration of porcine colostrum immunoglobulin IgA (Immunoglobulin A) and application of the primer pair. According to the invention, the SNP marker which is extremely remarkably related to the IgA concentration of the porcine colostrum immunoglobulin is positioned at the 74703937th site of the No.16 chromosome of a porcine reference genome. The invention reveals that the SNP site has an obvious additive effect, that is, the colostrum IgA concentration of a favorable homozygote (GG) is obviously higher than that of a heterozygote (TG), and the heterozygote is obviously higher than that of an unfavorable homozygote (TT) (GG > TG > TT). The genetic characteristic means that in breeding practice, the frequency of G allelic genes is improved through continuous breeding, the colostrum quality of pig herds can be continuously improved, meanwhile, the optimal colostrum IgA phenotype and progeny disease resistance can be obtained by establishing a homozygous core group of the GG genotype, and the method has extremely high breeding upper limit and application value.

The utility model discloses a drying machine for bovine colostrum powder production, and relates to the technical field of drying machines. Comprising a drying main body, the drying main body is provided with a processing mechanism used for drying bovine colostrum powder production, the processing mechanism comprises a stirring assembly, an air feeder is turned on, the air feeder feeds air into an electric heater, the air is heated by the electric heater into hot air, and the hot air enters an arc pipe; then the hot air is evenly blown into all parts of the drying body through the vertical pipes and the nozzles evenly distributed on the arc pipes, when the vertical shafts rotate, the top ends of the vertical shafts drive the fan blade plates to rotate, and the hot air fed into the drying body through the nozzles flaps downwards through the fan blade plates, so that the hot air is better dispersed in the drying body; and the drying efficiency and uniformity are further improved, it is ensured that all parts of the materials can be subjected to the uniform hot air effect, the problem of local overheating or insufficient drying is solved, and the drying efficiency is improved.

The utility model relates to the technical field of drying devices, in particular to a colostrum immunoglobulin low-temperature drying device which comprises an upper-section tower body, and an extension drying assembly is arranged on the inner side of the upper-section tower body. The extended drying assembly comprises a spiral flow guide plate fixedly connected with the top of the inner wall of the upper-section tower body, and flow equalizing holes are formed in the inner side of the spiral flow guide plate. According to the utility model, through the arrangement of the extended drying assembly, irregular eddy current of the upper section of the tower body is converted into stable spiral airflow, the droplet retention time is prolonged, and the diversion cone forcibly divides central airflow, forces the airflow to deflect towards the tower wall, eliminates the short circuit phenomenon of the central airflow, and prolongs the droplet retention time; and through the arrangement of extending the drying assembly again, the flow guide cone and the annular spoiler jointly form a spiral airflow track, the fogdrop bypassing distance is increased, the Venturi effect is generated through the through hole gradual shrinkage type hole channel design, and turbulent mixing is enhanced while the airflow speed is reduced.

A colostrum collection device includes a lower funnel-shaped component and an upper bulb component integrated with the lower funnel-shaped component. The colostrum collection device also includes a cap for sealing the lower funnel-shaped component. The colostrum collection device may be attachable to a T-shaped adapter.

Provided are compositions and methods for alleviating symptoms or treating gluten-related diseases. In some embodiments, the compositions include colostrum from cows that are immunized with gluten or partially digested gluten.

The utility model provides an auxiliary feeding device for discarding small pandas, which comprises a young panda breeding box, a partition plate is arranged in the young panda breeding box, and a food luring trough is arranged in a female panda room and is arranged at the upper part of the partition plate; a through hole is formed in the partition plate and corresponds to the breast of a female animal; a fixing device is further arranged in the female animal chamber and comprises a fixing plate, the fixing plate is slidably mounted in the female animal chamber and provided with a push-pull assembly, and one end of the push-pull assembly extends out of the female animal chamber. According to the utility model, the breast of the female animal is exposed in the through hole by utilizing food, and the female animal is kept in the posture through the fixing device, so that an opportunity of directly contacting with colostrum is created for the discarded baby of the small panda, the discarded baby of the small panda can obtain the colostrum, and the feeding success rate of the discarded baby of the small panda is effectively improved.

The invention discloses application of an SNP (Single Nucleotide Polymorphism) marker influencing the colostrum yield of sheep in a PTPRK gene. The marker is located on a PTPRK gene of a sheep chromosome 8, the specific SNP marker site is C / T base mutation at the 488 bp position of SEQ ID NO: 1 in a sequence table, and the colostrum yield of TT and CT genotype sheep individuals at the site is remarkably higher than that of CC genotype individuals. Hu sheep is used as a research object, PCR is used for amplifying a DNA sequence of an eighth exon of a sheep PTPRK gene, the sequence has an SNP variation site, the colostrum yield of a specific genotype Hu sheep individual at the variation site is analyzed, and the Hu sheep individual is selected and reserved for breeding according to the colostrum yield, so that excellent individuals with high colostrum yield are rapidly screened, the breeding process of a high colostrum yield population is accelerated, and the breeding efficiency of the sheep PTPRK gene is improved. A marker resource is provided for marker-assisted selection breeding of the colostrum yield of the sheep.

This invention discloses a composition with bone-health-promoting functions and its applications, belonging to the field of microbial engineering. The composition comprises milk calcium, colostrum basic protein, and Bifidobacterium breve i1088 powder. The composition provided by this invention, which has a synergistic effect between milk calcium, colostrum basic protein, and Bifidobacterium breve i1088 powder, enhances the conversion rate of calcium from the blood to bone through the action of probiotics, thereby improving the actual utilization rate of calcium and effectively promoting bone health. Experimental data show that this composition significantly increases bone mineral density, bone volume fraction, and trabecular thickness in a female rat osteoporosis model, and significantly reduces trabecular spacing in the same model. The composition provided by this invention is suitable for promoting bone health and preventing and / or improving osteoporosis.

The invention is based on the finding that incubating a Cryptosporidium gp40 protein with an aziridine, significantly increases its immunogenicity. When used as a vaccine, this allows a reduction of the dose, which improves economic feasibility and safety. Consequently the aziridine-treated gp40 can now be used as a safe and effective subunit-vaccine for humans or non-human-animals against Cryptosporidiosis. Specifically for new-born ruminants a vaccination by way of colostral transfer was found to be very effective in reducing clinical signs of Cryptosporidiosis, especially diarrhoea.

The invention discloses a milk feeding method for calves. The invention provides a milk feeding method for calves, and the method comprises the following steps: milk feeding in a first stage: feeding the calves with colostrum; milk feeding in the second stage, the milk feeding in the second stage comprises the steps that the calves are fed with transition milk for at least one day from the second day after the calves are born, and the brix degree of the transition milk is larger than or equal to 16% or the IgG is not lower than 30 g / L; in the third stage, milk feeding is conducted, and the milk feeding in the third stage comprises the step that the calves are fed with ordinary milk till the calves are more than 60 days old. Through the innovative feeding mode of multi-stage milk feeding and in combination with a systematic breeding strategy, the early-stage health level of the calves is comprehensively improved, and healthy development of intestinal tracts of the calves is promoted.

The invention discloses a muscle-building dietary flavone compound protein composition as well as a preparation method and application thereof, and belongs to the field of dietary supplements. The composition is prepared from the following components in parts by weight: 50 to 80 parts of concentrated whey protein powder, 5 to 20 parts of separated whey protein powder, 0.01 to 3 parts of hydrolyzed whey protein powder, 0.1 to 1 part of bovine colostrum powder, 0.01 to 0.05 part of kaempferol and 0.01 to 0.1 part of glucomannan. The composition can improve the muscle synthesis and growth rate, inhibit muscle reduction caused by sarcopenia, improve the muscle oxidation resistance, accelerate the muscle repair speed and activate the protein synthesis rate-limiting enzyme AKT and the growth kinase ERK. The composition can be used for preparing food, special diet and health food.

1. The name of the product under this design: Packaging can (cow colostrum powder nutritional milk powder). 2. Purpose of this design product: This design product is used for product packaging. 3. The key design points of this product are the combination of shape, pattern and color. 4. The picture or photo that best illustrates the key points of the design: main view. 5. The design for which protection is sought includes color.

1. The name of the design product: packaging box (black soil mother fukang bovine colostrum powder capsule). 2. The use of the design product: for food packaging. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best shows the design points: front view. 5. The design for which protection is sought includes color. 6. The bottom view of the design is not the common face when used, and the bottom view is omitted.

This invention relates to a method for preparing and applying a fat emulsion injection, belonging to the field of pharmaceutical technology. The preparation steps include preparing an oil phase using egg yolk lecithin with a specific PC and PE mass ratio as an emulsifier, mixing it with an aqueous phase to obtain a colostrum, homogenizing the colostrum, and then adding sodium oleate to obtain the fat emulsion injection. The fat emulsion injection prepared by the method of this invention has the characteristics of a low SPAN value and a small number of large-diameter emulsion particles.