497 results about "Collagen peptide" patented technology

The invention relates to the technical field of exosomes, in particular to an exosome compound preparation with a hair growing effect and a preparation method of the exosome compound preparation. Comprising 12 to 22 parts of ginsenoside Rb1, 15 to 12 parts of biotin tripeptide-15, 8 to 15 parts of diammonium glycyrrhizinate, 50 to 70 parts of fish collagen peptide, 10 to 20 parts of soybean peptide, 0.5 to 4.5 parts of SHH protein, 0.5 to 2.5 parts of SMO inhibitor, 0.5 to 1.5 parts of HhSP protein, 5 to 10 parts of N-acetyl tyrosine, 0.1 to 2 parts of hyaluronic acid, 0.1 to 1 part of melatonin, 0.1 to 1 part of quercetin, 0.1 to 1 part of kaempferol, 0.1 to 1 part of tanshinone, 0.1 to 1 part of biotin and 0.1 to 1 part of vitamin A. The compound preparation is combined with exosomes from various sources, so that the hair papilla cell function is synergistically enhanced, and the damaged hair follicle structure is repaired.

The invention provides an enzyme response type supramolecular PDRN-mini ECM liposome and a preparation method and application thereof.The enzyme response type supramolecular PDRN-mini ECM liposome comprises phospholipid, a membrane stabilizer, a supramolecular compound and an emulsifier, a water phase formed by the supramolecular compound and the emulsifier serves as an inner core, and the supramolecular compound is formed by PDRN and mini ECM through intermolecular acting force; the mini ECM is formed by self-assembly of collagen peptide, elastin and hyaluronic acid. The supramolecular PDRN-mini ECM liposome with uniform particle size and good stability is obtained through a microfluidic technology, the process is simple, the controllability is high, and amplification is easy.

The invention discloses a preparation method of micromolecular active collagen peptide, which comprises the following steps: (1) cutting fresh leather into fragments, pretreating the leather with a sodium bicarbonate solution, rinsing the leather with deionized water, and refrigerating and storing; (2) mixing papain, bromelain, pancreatin, pepsase, alkaline protease, neutral protease and flavourzyme to obtain a compound enzyme preparation; (3) performing high-pressure steam sterilization on the leather at 110-140 kPa and 120-122 DEG C to obtain leather with the hydrolysis degree of 75-85%, then adding distilled water into the leather to obtain mucilage, then adding a compound enzyme preparation into the mucilage, reacting for 5.5-6.5 hours at the pH of 6.8-7.2 and the temperature of 50-55 DEG C, and then performing enzyme inactivation at the temperature of 85-95 DEG C; and (4) after the reaction system is cooled to room temperature, purifying and centrifuging the reaction system, and taking clarified supernate, thereby obtaining the product. Different animal skins are treated, the proportion of peptide fragments with the molecular weight smaller than 1000 Da of the prepared small-molecule active collagen peptide is larger than or equal to 80%, and the hydroxyproline content is larger than 3%.

The invention provides a fish collagen peptide with a whitening effect and a preparation method thereof, and the method comprises the following steps: performing glycosylation modification treatment on fish collagen by using glucose, and then sequentially treating the fish collagen with gastric juice and intestinal juice to obtain the fish collagen peptide with a polypeptide sequence with glycosylation sites on a peptide chain. According to the invention, the fish collagen peptide with a remarkable inhibition effect on tyrosinase is obtained.

The invention discloses a plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promoting, blood stasis removing, thrombolysis, collateral dredging and microcirculation improving, and relates to the technical field of medicine and food homology dietary therapy. Soybean protein isolate and earthworm protein are used as core thrombolytic active raw materials, isomaltooligosacharide, xylitol, German Jilida collagen peptide, soybean peptide powder, Belgian imported inulin, red yeast rice and natto powder are compounded, microcrystalline cellulose and magnesium stearate are used as auxiliary materials, and probiotics / metabiotics strains such as rhamnolactobacilli JYLR-005 and the like can be selectively added. The raw materials have a synergistic effect through precise matching, plasmin and lumbrukinase peptide in earthworm protein can directly dissolve thrombus fibrin, natto powder and red yeast rice assist in lowering lipid and dissolving thrombus, multiple active peptides and prebiotics regulate intestinal microecology to improve microcirculation of the whole body, probiotics / metabiotics further strengthen the metabolic capacity of the body, no chemical medicine is added in the whole process, and the traditional Chinese medicine composition is free of toxic and side effects and free of toxic and side effects. The safety is high; the dietary therapy composition can achieve postoperative rehabilitation conditioning of cardiovascular and cerebrovascular diseases through daily consumption, effectively promote blood circulation to remove blood stasis, dissolve thrombus and dredge collaterals, improve microcirculation and relieve various discomfort caused by blood vessel clogging, raw materials are easy to obtain, compatibility is scientific, and the dietary therapy composition is suitable for large-scale production and popularization.

To provide a topical skin preparation that effectively promotes collagen production within the skin, exhibits excellent usability, and effectively enhances post-use stratum corneum moisture content.SOLUTION: A topical skin preparation comprises niacinamide, a heparin-like substance, dipotassium glycyrrhizinate, a collagen peptide, a yeast extract, and glycylglycine. It is preferable that the topical skin preparation further contains hydrogenated soybean phospholipids and phytosterols. It is more preferable that the topical skin preparation has a niacinamide content of 5 mass% or more. It is also preferable that the topical skin preparation further contains at least one plant extract selected from Arnica montana and Plantago major.SELECTED DRAWING: Figure 1

The invention provides a preparation method of yak bone collagen peptide, a composition for promoting skeletal development and application of the composition, and relates to the technical field of health food. The preparation method comprises the following steps: carrying out ultrasonic pretreatment on yak bones, and degreasing through supercritical CO2 to obtain a degreased product; mixing the degreased product with a fishy smell removing agent to obtain a fishy smell removing product; the fishy smell removing agent is an aqueous solution of a plant extract; the plant extract is selected from at least one of amomum tsao-ko extract, turmeric extract, green tea extract or momordica grosvenori extract; the fishy smell removal product is subjected to an enzymatic hydrolysis reaction through an immobilized compound enzyme reactor, wherein the compound enzyme is prolyl endopeptidase, papain and ficin; obtaining a crude product; carrying out ultrafiltration by adopting a filter membrane with the molecular weight cut-off of 1kDa, and adsorbing through macroporous resin. The yak bone collagen peptide and the composition prepared by the invention can obviously improve the body length, promote the skeletal development and promote the secretion of growth hormone, and meet the growth requirements of children.

The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more collagen mimetic peptides, optionally attached to one or more therapeutic compounds or one or more imaging compounds, for use in methods of treating, preventing, ameliorating, curing and diagnosing certain diseases and physical disorders in humans and veterinary animals, as well as methods of manufacturing such composition. The invention also provides medical devices comprising one or more such compositions of the invention. The invention also provides methods of use of such compositions and devices in treating and diagnosing certain diseases and physical disorders in humans and veterinary animals, including ocular diseases or disorders, skin diseases or disorders, certain cancers, particularly intraluminal cancers, gastrointestinal diseases or disorders, genitourinary tract diseases or disorders, fibrotic diseases / disorders and rheumatic diseases / disorders.

The invention discloses a composite plant polypeptide composition with the effects of repairing pancreas and reducing blood sugar. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 50 parts of ginsenoside, 5 to 30 parts of radix astragali seu hedysari extract, 3 to 20 parts of radix rehmanniae polysaccharide, 2 to 15 parts of radix trichosanthis alkaloid, 5 to 25 parts of rhizoma dioscoreae polysaccharide, 5 to 30 parts of bitter gourd polypeptide, 3 to 20 parts of folium mori alkaloid, 8 to 40 parts of rhizoma polygonati polysaccharide, 5 to 25 parts of fructus hippophae flavone, 10 to 35 parts of wheat germ peptide, 2 to 15 parts of coptis berberine, 10 to 45 parts of corn stigma polysaccharide and 3 to 20 parts of saussurea involucrata polyphenol. 1-10 parts of sophora flavescens total alkaloids, 5-25 parts of a dendrobium extract, 5-30 parts of a radix puerariae extract, 8-35 parts of L-arabinose and 10-40 parts of small molecule peptides; 20 to 100 parts of collagen peptide and 15 to 80 parts of albumin peptide; 5-50 parts of microcrystalline cellulose, 3-30 parts of fructo-oligosaccharide and 0.5-5 parts of magnesium stearate; the limitation of single sugar control or simple component mixing in the prior art is broken through, a synergistic system of plant active components and functional polypeptides is constructed, and the purity and retention rate of the plant active components are improved by optimizing the extraction process.

The invention provides a beautifying composition and application thereof in whitening, anti-inflammatory and anti-aging products, and belongs to the technical field of cosmetics. The beautifying composition is prepared from collagen peptide, sodium hyaluronate and ergothioneine, wherein the mass concentration ratio of the collagen peptide to the sodium hyaluronate to the ergothioneine is (75 to 85) to (3.5 to 10) to (0.4 to 3.5); the beautifying composition shows remarkable advantages in the aspects of collagen regeneration and skin improvement, the collagen content can be remarkably increased, and multi-effect collagen regeneration promotion is achieved by inhibiting collagen degrading enzyme MMP-1 and up-regulating TGF-beta1; the content of AQP3 and HA can be increased, and water locking and moisturizing of the skin are enhanced; by activating an Nrf2 pathway, the SOD2 level is improved, IL-6 and IL-1alpha are inhibited, and the antioxidant, anti-inflammatory and whitening effects are achieved; the thickness of an epidermal layer and the density of dermal fibroblasts can be remarkably improved, wrinkle resistance and repairing are effectively achieved, and the skin structure is improved.

The invention belongs to the field of bioactive protein peptide materials, and provides an animal-derived composite fermented skin-tendering protein peptide and a preparation method thereof. According to the invention, bovine-derived collagen and fish-derived protein are subjected to synergistic fermentation to prepare a protein peptide core, and the outer surface of the protein peptide core is coated with an edible gelatin and chondroitin sulfate composite layer; the excellent performance that a small molecule peptide core with the molecular weight being 500-1500 Da, a stable coating layer with the coating rate being 80-99%, the glycine-proline-hydroxyproline sequence collagen peptide fragment accounting for 30-60% and the pH responsive swelling ratio being 1.5-3.0 are achieved, the technical problems that traditional protein peptide is poor in stability and low in bioavailability are solved, and the protein peptide has wide application value in the field of skin care products.

The invention provides a nutrition enhancer beneficial to bone health of middle-aged and elderly people, a preparation method of the nutrition enhancer and application of the nutrition enhancer in preparation of medial care food, and belongs to the field of nutritious food. The nutrient supplement comprises a plant fermentation product, osteopontin peptide, collagen peptide, N-acetylglucosamine and calcium, vitamins and mineral substances can be added, and the plant fermentation product is obtained by performing anaerobic fermentation on rhizoma drynariae and chestnuts through a complex microbial inoculant composed of lactobacillus reuteri and bifidobacterium longum subsp. Longum; the collagen peptide is prepared by performing enzymolysis on bovine bones through alkaline protease and flavourzyme; the hydrogel is prepared by adopting a sodium alginate-calcium chloride-carboxymethyl chitosan micro-capsule embedding process. An in-vitro experiment shows that the nutrition enhancer can remarkably promote osteoblast proliferation, differentiation and mineralization; animal experiments show that the bone mineral density of osteoporosis model mice can be effectively improved. The nutrition enhancer disclosed by the invention is suitable for preparing care food and bone health products, and has a remarkable effect of improving bone health of middle-aged and elderly people.

The invention relates to the technical field of functional food, in particular to a panax quinquefolius probiotic beverage and a preparation method thereof, and the beverage comprises the following components: 30-50 parts of panax quinquefolius pulp; 20 to 40 parts of sea buckthorn raw pulp; 1 to 5 parts of marine collagen peptide powder; 1 to 5 parts of a probiotic fermentation agent; 0.5 to 3 parts of calcium beta-hydroxy-beta-methyl butyrate; 0.5 to 10 parts of an auxiliary material; the pH (Potential of Hydrogen) value of the beverage is 3.8 to 4.2. The instability of a compound system is solved by combining precise pH control, specific stabilizer compounding and a high-pressure homogenization technology, the activity of rare saponin is improved through enzymolysis conversion, the adding sequence of the raw materials is optimized, heat-sensitive components are reserved by adopting ultrahigh-pressure cold sterilization, and meanwhile, the taste is improved by blending the natural flavor of sea-buckthorn and a natural sweetening agent. Therefore, the problems of poor compounding stability, difficulty in activity retention and the like in the prior art are solved.

The invention relates to the field of biological product preparation, in particular to a preparation method of high-activity oyster-derived small molecule peptide. The method comprises the following steps: selecting fresh meat of pacific oysters or ostrea rivularis as a raw material, degreasing, adding water, crushing, filtering, sequentially carrying out compound protease and neutral protease hydrolysis, implanting a sensor and a probe in hydrolysis, monitoring in real time, and dynamically adjusting reaction conditions; adding a targeting microcapsule wrapping an ascorbic acid glutathione composite protective agent, and releasing the protective agent when a target peptide signal is detected; separating and concentrating through a gradient membrane, and purifying the target peptide by using a molecular imprinting chromatographic column; carrying out alkaline hydrolysis on enzymatic hydrolysis residues to prepare chitosan for cyclic utilization, carrying out enzymatic hydrolysis on residual residues to generate collagen peptide, treating and recycling wastewater, and recovering protease. According to the method, the technical effects that the high-activity and high-purity target peptide is prepared, the resource utilization rate is increased, the production cost is reduced, the target peptide has good oxidation resistance and biological activity, the intestinal enzyme degradation rate is reduced after glycosylation modification, and the blood half-life period is prolonged are achieved.

The invention relates to the technical field of functional nutritious food, in particular to multi-layer skin nutrition powder with a whole-spectrum skin growth and repair promoting effect and a preparation method and application thereof, the core of the multi-layer skin nutrition powder is composed of a collagen peptide system (60-62%), a proteoglycan system (20-22%) and the like, collagen peptide is compounded with three sources of cattle, fish and chicken, and the multi-layer skin nutrition powder has the advantages that the multi-layer skin nutrition powder is prepared; according to the present invention, with the combination of the following components, the skin structure and activity are jointly promoted by using the synergistic effect of the functional polypeptide compound (2.5-3.5%) and the plant active component (3.5-4.5%) rich in asiaticoside and procyanidine, and the nutrition enhancers (4-5%) such as L-ascorbic acid and amino acid chelated zinc and the food-grade auxiliary materials (8-10%) such as microcrystalline cellulose are integrated in the formula, such that the various systems achieve the synergistic effect so as to achieve the effect of nourishing the skin; through the synergistic compatibility of the three-source collagen peptide, the comprehensive supplement of various types of collagen in skin tissues is realized.

The invention discloses a composite combined preparation for synergistically treating and conditioning diabetes, relates to the technical field of foods, health foods or dietary supplements for adjuvant therapy and health care of diabetes, and in particular relates to a composite combined preparation for synergistically treating and conditioning diabetes. The preparation comprises albumin peptide, saussurea involucrata culture, vitamin B1, vitamin B2, wheat oligopeptide, corn oligopeptide, collagen peptide, mulberry leaf extract, rhizoma polygonati extract, sea-buckthorn extract, isomaltitol, maltodextrin, ginseng extract and bitter gourd extract. Through the synergistic effect of all the components, comprehensive auxiliary conditioning on diabetes is realized from multiple targets of maintaining colloid osmotic pressure and nutrition, regulating glycolipid metabolism in multiple ways, protecting pancreatic beta cell functions, enhancing insulin sensitivity, preventing nerve and blood vessel complications, meeting special diet requirements and the like. The composition can be prepared into food, health-care food or dietary supplement and other dosage forms.

The invention belongs to the technical field of drying equipment, and particularly relates to drying equipment and a working method thereof.The drying equipment is characterized in that a cutter in a foam crushing mechanism rotates around a vertical shaft so as to crush foam generated by fish collagen peptide deposited in an inner cavity; a cutter in the foam crushing mechanism rotates around a transverse shaft so as to separate fish collagen peptide on the cutter; the problem that in the process of drying the fish collagen peptide solution, generated foam expands to the limit and is broken, so that the vacuum degree fluctuates can be solved, meanwhile, the foam breaking mechanism rotates while revolving, and the fish collagen peptide solution bonded to the cutter is thrown away under the action of centrifugal force in two different directions; the situation that due to local high temperature of the surface of the cutter, fish collagen peptide adhering to the cutter is crystallized is avoided, nitrogen is supplemented into the inner cavity, and even if a fish collagen peptide solution is decomposed to generate oxygen, it can be guaranteed that the oxygen concentration in the inner cavity is kept at the low level.

The invention relates to the technical field of fluid circulation of collagen peptide production equipment, in particular to a collagen peptide mechanical seal water circulation system which comprises an intelligent control unit, a cooling unit and an ultrasonic descaling unit. Converting the vibration spectrum into a peptide molecule aggregation tendency coefficient, correcting a viscosity predicted value to generate a flow control weight, allocating resources to a cooling unit according to a hydrolysis risk thermodynamic diagram, directionally cooling a high-risk area, activating an ultrasonic descaling unit and reducing the flow when the aggregation coefficient continuously rises and exceeds a limit, the system generates cooperative control quantity through rolling of a three-dimensional dynamic weight matrix, synchronously adjusts the rotating speed of a water pump, the opening degree of a cooling valve and ultrasonic power, solves the problems of unstable flowing, peptide chain hydrolysis and aggregation scaling, and guarantees production stability and product quality.

The invention discloses a high-calcium chelating activity collagen peptide prepared based on chicken bones, a peptide calcium chelate and application, an ultrasonic-assisted enzymolysis technology is utilized to destroy a collagen cross-linked structure through an ultrasonic cavitation effect, and three-stage enzymolysis time sequence regulation is combined, so that the hydrolysis rate of the collagen peptide reaches 33.18 + / -0.84%. The collagen peptide provided by the invention has relatively high calcium chelating activity, and the peptide calcium chelate is stable in structure in an intestinal neutral environment and under a weakly alkaline condition and is beneficial to intestinal absorption of calcium.

The application discloses a soybean peptide preparation device and production process, and relates to the technical field of collagen peptide extraction. The soybean peptide preparation device comprises an enzymolysis tank, a feeding cylinder arranged at the middle part of the inner side of the enzymolysis tank, and a rotating drum arranged at the outer side of the feeding cylinder. At least one group of material limiting net frames are arranged at the outer side of the rotating drum. A half-cylinder type net bag one is arranged in the transmission channel of the material limiting net frame. The half-cylinder type net bag one is a half-cylinder type net cylinder. A half-cylinder type net bag two is arranged in the half-cylinder type net bag one. The half-cylinder type net bag two is composed of two groups of quarter net bags which can be opened and closed relative to each other. The rotation of the material limiting net frame is driven by the rotating drum, and the passive driving of the self-driving assembly in response to the rotation of the material limiting net frame drives the combined alternating operation of the two pairs of material buffering net bags and the stirring components in the material limiting net frame. The soybean material is rotated along the circumferential direction of the enzymolysis tank, and is gradually and stepwisely circulated back from top to bottom, so that the different-dimension synchronous enzymolysis reaction of the soybean material with the enzymolysis solution in the tank is realized.

The invention relates to a low-temperature gradient enzymolysis technology for collagen peptide in the body wall of a sea cucumber, and discloses mild decomposition and efficient extraction of collagen in the body wall of the sea cucumber by virtue of a multi-section temperature zone reaction, enzyme seed compounding control and on-line regulation system. And the collagen peptide with concentrated molecular weight, strong biological activity and high terminal product quality is prepared by the low-temperature gradient enzymolysis technology. The method is characterized by comprising the following steps: cutting the body wall of the sea cucumber to obtain a particle size suitable for enzymolysis, adding the cut body wall of the sea cucumber into a neutral buffer solution, stirring at normal temperature, and adjusting the pH value to 6.5-7.5, so that the tissue of the body wall of the sea cucumber is fully expanded and uniformly dispersed to be more suitable for the subsequent enzymolysis process; the method comprises the following steps: carrying out staged reaction on the body wall of the sea cucumber and an enzyme at different temperatures, carrying out fine separation and terminal treatment on an enzymatic hydrolysate, and immediately cooling a system to 4 DEG C after the reaction of the enzymatic hydrolysate is finished.

The invention discloses a preparation method of an anti-aging body-building nutritional product. The preparation method comprises the following steps: step 1, weighing raw materials in parts by weight; 2, pretreating the tea polyphenol and the tea micromolecules; 3, mixing the pretreated tea polyphenol and tea micromolecules with other raw materials; step 4, adding maltodextrin and erythritol into the mixed solution, and stirring and mixing; and step 5, removing agglomerated particles, and tabletting or filling into capsules. According to the present invention, by adding the collagen peptide, the oxidation resistance of the product can be increased, the oxidative damage after exercise can be effectively relieved, the cell aging can be delayed, the traditional sucrose is cancelled, the maltodextrin and the erythritol are adopted to replace the sucrose, and the product is suitable for the long-term consumption of the body-building crowd; the preparation method solves the problems of easy oxidation and activity loss of core components in a traditional preparation method, so that substances such as tea polyphenols and tea micromolecules are more easily absorbed and utilized by human bodies.

The invention discloses a fish hydrolyzed collagen peptide-based flavor beverage and a preparation method thereof, and relates to the technical field of food beverages. The flavored beverage comprises the following raw materials: fish hydrolyzed collagen peptide, a compound flavor modification stabilizer, a compound sweetening agent, concentrated fruit and vegetable juice, casein phosphopeptides, VC magnesium phosphate, zinc lactate, a low-nucleic-acid yeast extract, sodium hyaluronate, an acidity regulator and purified water. The compound flavor modification stabilizer is matched with the low nucleic acid yeast extract to form synergistic flavor regulation and control, the hydrophobic bitter peptide fragment of the fish hydrolyzed collagen peptide and the fishy smell characteristic group are wrapped from the molecular level, and meanwhile, the soft modification on the sensory level is realized through the gamma-aminobutyric acid; the effect of debitterizing and deodorizing without adding artificial essence and a large amount of cane sugar is achieved, the product flavor is natural and harmonious, the sour and sweet taste is palatable, the beverage completely conforms to the current healthy consumption trend of low sugar and no artificial addition, and the problem that the beverage has flavor defects is solved.

The invention discloses a compound special diet and a preparation method thereof, and belongs to the technical field of special diets. The diet is prepared from 40-45 parts of cassia seed powder as a main raw material, 17-22 parts of compound black bean powder, 10-16 parts of collagen peptide powder and the like as well as 1-2 parts of a compound coating agent (not included in a formula proportion). The preparation method comprises the steps of sieving, ingredient mixing, dry granulation, tabletting, coating and inner packaging, wherein the sieving adopts a 40-mesh sieve, the mixing is carried out for 30 minutes at the speed of 40HZ, the dry granulation ensures that the granularity is greater than or equal to 70%, the tablet weight is controlled to be 0.78-0.82 g during tabletting, the hardness is controlled to be 90-150N during tabletting, and the coating adopts specific parameters. Through synergistic interaction of the raw materials and process optimization, the activity of the components is reserved, the stability and palatability of the product are guaranteed, the method is suitable for industrial production, and the special dietary function requirements are met.

The application discloses a kind of composition with immunoregulation and anti-aging function and preparation method thereof, and core component is marine collagen peptide, fusion polypeptide CPF-1, targeting senescent cell monoclonal antibody mAb Senolix, five gallate acyl glucose (PGG) and Hericium erinaceus polysaccharide.Fusion polypeptide CPF-1 is designed by domain fusion strategy, with collagen binding, immune activation and antibacterial function;Monoclonal antibody mAb Senolix targets the surface antigen p16^(INK4a) of senescent cell, and removes senescent cell by ADCC effect.The composition significantly improves immune cell activity, promotes collagen synthesis and reduces chronic inflammation through the synergistic effect of multiple components, and shows excellent immunoregulation and anti-aging effect in in vitro cell model and immunosuppressed mouse model, and can be used for developing immune enhancer, anti-aging drug or functional food.

The invention discloses a skin barrier repairing oral liquid based on cubilose peptide-collagen-traditional Chinese medicine compounding. The skin barrier repairing oral liquid is prepared from the following raw materials in percentage: 30 to 50 percent of skin nutrition base powder, 5 to 10 percent of three-type collagen peptide, 0.6 to 1 percent of cubilose peptide and 30 to 70 percent of traditional Chinese medicine herbal extract. The three-type collagen peptide disclosed by the invention can be used for directly supplementing key structural protein of a dermis layer of skin, promoting collagen fiber regeneration, improving skin elasticity and reducing fine wrinkles; the cubilose peptide is small in molecular weight, easy to absorb and capable of providing amino acid raw materials for skin cells and enhancing cell activity, the cubilose peptide and the collagen peptide cooperate to solve the problem of insufficient collagen synthesis caused by age increase, the skin nutrient base powder, the collagen peptide and the cubilose peptide are nutrients needed by skin barriers, and the herbal medicine is used for promoting nutrient absorption, mobilizing qi and blood of the body and improving the taste.

The utility model discloses a stirring device for collagen peptide preparation, which comprises a mounting frame, a tank body is fixedly mounted on the mounting frame, a moving frame is mounted on the mounting frame in a sliding manner, a mounting cover is arranged on the moving frame, the mounting cover is rotatably connected with the moving frame through a first mounting pipe, an adjusting disc is arranged in the mounting cover, and the adjusting disc is rotatably connected with the moving frame through a second mounting pipe. The adjusting disc is rotatably connected with the mounting cover through a second mounting pipe, the second mounting pipe is sleeved with a third gear, a rack is slidably mounted in the mounting cover, three groups of guide rails which are annularly distributed are fixedly mounted on the mounting cover, and three groups of stirring frames which are annularly distributed are slidably mounted in the mounting cover; adjusting rods are fixedly mounted on the three groups of stirring frames, three groups of annularly distributed adjusting grooves are formed in the adjusting disc, and the adjusting disc rotates in the mounting cover and is matched with the three groups of guide rails and the adjusting rods to adjust the distance among the three groups of stirring frames, so that the inner ring and the outer ring of the tank body are stirred in turn.

The invention belongs to the technical field of biological medicine manufacturing, and particularly relates to preparation and application of collagen peptide with whitening activity. The preparation method of the collagen peptide with the whitening activity comprises the following steps: step A, inoculating bacillus subtilis into a culture medium containing a moringa oleifera leaf extracting solution, fermenting for 6-12 hours, inoculating aspergillus niger, continuously fermenting for 36-48 hours, sterilizing, centrifuging, and taking supernate to obtain moringa oleifera leaf fermentation liquor; and step B, scaling the fish skin, cleaning, drying and crushing, adding the moringa oleifera leaf fermentation liquor, reacting for 6-10 hours at the pH value of 6.0-7.0 and the temperature of 35-45 DEG C, and performing ultrafiltration, filtrate concentration and freeze-drying to obtain the collagen peptide. The preparation process has the advantages of low cost, greenness and high efficiency, and the prepared collagen peptide shows the activity of inhibiting tyrosinase and can be applied to preparation of skin care products or medicines with a whitening function.

The invention discloses a lutein composition for relieving asthenopia and a preparation method of the lutein composition, and belongs to the field of functional foods. Phycocyanin and kelp polyphenol are mixed and react to obtain modified phycocyanin; fucoidin and beta-glucuronidase are mixed and react to obtain modified fucose; mixing the fish collagen peptide and zinc chloride to react to obtain a collagen peptide-zinc chelate; the xanthophyll siliceous cage compound and the modified phycocyanin are mixed and react to obtain a first compound; mixing and reacting the first compound and modified fucose to obtain a second compound; mixing and reacting the second compound, collagen peptide-zinc chelate and krill oil to obtain a lutein compound; mixing and reacting the second compound, collagen peptide-zinc chelate and krill oil, adding trehalose, and mixing and reacting to obtain a xanthophyll compound; and mixing the xanthophyll compound and maltodextrin to obtain the xanthophyll composition.

The invention discloses a collagen peptide composition with a skin saccharification resisting effect and a preparation method of the collagen peptide composition, and belongs to the technical field of health care products. The composition is prepared from the following raw materials in parts by mass: 50-60 parts of collagen peptide, 9-15 parts of decarboxylated carnosine, 5-8 parts of peony peptide, 2-4 parts of fucoxanthol, 5-8 parts of tricholoma lobayense heim polysaccharide, 1-2 parts of sesamin and 3-7 parts of cyclodextrin. The collagen peptide composition is prepared through a reasonable material compounding agent inclusion technology, the anti-saccharification activity of the collagen peptide composition is remarkably improved, and a better scheme is provided for resisting skin saccharification.