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74 results about "Collagen peptide" patented technology

Collagen peptide is a natural body protein produced inside the body. Collagen and elastin in the body are produced to prevent dermal layers of the skin from developing skin folds. After they are created, these substances create collagen peptide bundles, resulting in firm skin.

Method for preparing bone collagen peptide by dynamically regulating pH step-by-step enzymolysis and application thereof

PendingCN122325584AEnzymatic hydrolysisPh control
This application discloses a method and its application for preparing collagen peptides by stepwise enzymatic hydrolysis with dynamic pH control, belonging to the field of protein preparation technology. The method includes raw material pretreatment, stepwise enzymatic hydrolysis with dynamic pH control, and post-treatment to obtain collagen peptide products with a molecular weight distribution of 800-2000 Da. The obtained products can be used to prepare products with bone growth promotion functions. This application employs a combined process of stepwise enzymatic hydrolysis with dynamic pH control, alkali-thermal coupling pretreatment, and 2000 Da retention. The steps work synergistically: alkali-thermal treatment exposes enzyme cleavage sites, dynamic pH control enables efficient enzymatic hydrolysis, and 2000 Da retention of active components results in a significantly higher yield and content of collagen peptides compared to conventional processes. Animal experiments have demonstrated that the collagen peptides have bone growth promotion activity, and the mechanism of action has been revealed at the IGF-1 signaling pathway level.
Owner:HUBEI RUIBANG BIOTECHNOLOGY CO LTD

A compound nutritional composition beneficial for joint function improvement of sports population and application thereof

ActiveCN120661633BNutritionOxidative stress
This invention relates to a compound nutritional composition and its application. The compound nutritional composition comprises the following components: 1 part by weight of turmeric; 0.002-5 parts by weight of enzymatically hydrolyzed bone powder; and 0.02-0.2 parts by weight of cartilage powder containing type II collagen or 0.02-10 parts by weight of collagen peptide powder. The compound nutritional composition provided in this application addresses the specific osteoarthritis issues of athletes. By constructing an articular cartilage cell inflammation model and conducting population testing, the intervention effects of the compound nutritional composition provided in this application on exercise-related oxidative stress, inflammatory response, and pain perception are systematically evaluated. The aim is to overcome the limitations of traditional broad-based formulations and develop precise nutritional solutions that combine component synergy with exercise physiological adaptability, providing athletes with more scientific and effective joint health protection.
Owner:SHANGHAI MAXWIN HEALTH TECH CO LTD

Astaxanthin and collagen complex composition and preparation method thereof

This invention belongs to the field of functional food technology, specifically relating to an astaxanthin and collagen complex composition and its preparation method. The composition comprises the following components: 5 to 20 parts of astaxanthin phospholipid composite nanoparticles, 60 to 110 parts of glycosylated collagen peptides, 2 to 6 parts of hyaluronic acid-collagen peptide grafts, and 1 to 3 parts of curcumin-encapsulated components. The preparation method of the composition is as follows: S1, preparing an activated aqueous phase base; S2, sequential mixing and primary stabilization; S3, integrating the encapsulated components and fine homogenization; S4, final blending and degassing; S5, solid particle preparation. This invention, by constructing a synergistic system containing multiple modified functional components such as astaxanthin phospholipid composite nanoparticles and glycosylated collagen peptides, and employing a refined compounding process, effectively improves the physical stability of the product and synergistically enhances the bioavailability of the active ingredients and the overall antioxidant support efficacy.
Owner:YUNNAN VITAYUAN BIOTECHNOLOGY CO LTD

Collagen peptide with anti-aging effect and preparation method and application thereof

ActiveCN121293373BNucleotideAbsorption (skin)
This invention belongs to the field of cosmetic technology, specifically relating to a collagen peptide with anti-aging effects, its preparation method, and its application. The amino acid sequence of the collagen peptide is shown in SEQ ID NO.1, and the nucleotide sequence is shown in SEQ ID NO.2. This invention constructs and expresses a collagen peptide Sa1 by recombining the effective sequences of human type III and XVII collagen. This collagen peptide Sa1 exhibits significant antioxidant effects, is non-cytotoxic, and has good safety. Skincare products containing collagen peptide Sa1 can promote the absorption of collagen in the skin, effectively exert antioxidant effects, thereby improving skin elasticity and delaying skin aging.
Owner:DEZHOU KANGZE BIOPHARMACEUTICAL CO LTD

A collagen tripeptide composition, and a preparation method and application thereof

PendingCN122320236ATremellaFood technology
This invention discloses a collagen tripeptide composition, its preparation method, and its application, belonging to the field of food technology. The collagen tripeptide composition comprises the following raw materials in parts by weight: 80-200 parts of ray collagen peptide, 70-120 parts of collagen tripeptide, 100-300 parts of French flower and fruit powder, 300-600 parts of prickly pear powder, 300-500 parts of sage extract, 100-150 parts of tremella polysaccharide, 300-500 parts of wolfberry powder, and 100-300 parts of astragalus powder. The collagen tripeptide composition of this invention can reduce β-galactosidase activity, exhibiting a good anti-aging effect. Applying the collagen tripeptide composition of this invention can quickly replenish collagen and maintain skin elasticity.
Owner:JILIN HENGMEI YUCHUANG HEALTH TECH CO LTD +1

Andrias davidianus skin collagen peptide, and preparation method and application thereof

PendingCN122278984AEnzymatic hydrolysisGiant salamander
This application belongs to the field of biotechnology, specifically relating to giant salamander skin collagen peptides, their preparation methods, and applications. This application provides a method for preparing giant salamander skin collagen peptides. The method first pre-treats the fish skin, then performs ultrasonic-assisted extraction under acidic conditions to effectively promote collagen dissolution. The extract undergoes flocculation to remove impurities, significantly reducing interference from other proteins. The enzymatic hydrolysis stage employs a stepwise enzymatic hydrolysis strategy: first, a combination of alkaline protease and another specific protease is used for hydrolysis, sequentially cleaving the complex structure of giant salamander skin collagen to improve initial hydrolysis efficiency and generate specific intermediate peptides; subsequently, a flavor protease is added for further deep hydrolysis to achieve complete hydrolysis. This method has high enzymatic hydrolysis efficiency, controllable hydrolysis degree, concentrated molecular weight distribution of the obtained collagen peptides, high yield of the target product, and stable process.
Owner:BEIJING QINGYAN BOSHI HEALTH MANAGEMENT CO LTD +1

A traditional Chinese medicine composition for treating insomnia based on a modification of Zhang Zhongjing's Wumei Pill

ActiveCN120241942BCoptisMilk protein
This invention provides a composition comprising: 5-15 parts by weight of dried plum, 10-20 parts by weight of cinnamon twig, 10-20 parts by weight of ginseng, 3-8 parts by weight of angelica root, 5-15 parts by weight of asarum, 10-30 parts by weight of dried ginger, 5-15 parts by weight of Sichuan pepper, 5-15 parts by weight of phellodendron bark, 3-8 parts by weight of coptis root, 20-40 parts by weight of bitter wine, 20-30 parts by weight of japonica rice, 10-20 parts by weight of honey, 3-8 parts by weight of lily bulb, 40-60 parts by weight of polygonum multiflorum stem, 40-60 parts by weight of monkey head mushroom, 3-8 parts by weight of polygala root, and 5-15 parts by weight of poria cocos (a traditional Chinese medicine composition). Further, the composition comprises: 20-40 parts by weight of hydrolyzed milk protein, 20-40 parts by weight of fish collagen peptide, and 20-40 parts by weight of soybean peptide (a biological product). This invention also provides pharmaceutical preparations (especially pills) comprising the above composition, biological products, and methods for preparing the same. The composition has a significant effect on improving sleep and has broad application prospects.
Owner:HANGZHOU YUAN HEALTH MANAGEMENT CO LTD

A multi-stage separation and purification equipment for collagen peptides

PendingCN122278614AFiberEnzymatic hydrolysis
This invention discloses a multi-stage separation and purification device for collagen peptides, relating to the field of collagen processing technology. It aims to solve the technical problem of difficulty in separating and purifying collagenase raw materials due to their diversity, as demonstrated by existing equipment. The device includes an enzymatic hydrolysis tank with a multi-stage separation mechanism at its bottom. This mechanism comprises a drive rod assembly, a fixed cylinder assembly, and a centrifugal inner ball assembly. The drive rod assembly drives the centrifugal inner ball assembly to rotate within the fixed cylinder assembly. The centrifugal inner ball assembly expands radially due to centrifugal force, forming a variable-gap extrusion and grinding chamber with the inner wall of the fixed cylinder assembly. It has two working states: bone fragment crushing and fiber chopping. The centrifugal ball segments have grooves, within which arc blades are movably inserted. These arc blades automatically extend and retract according to the rotational speed under the control of an elastic telescopic rod. A linked defoaming mechanism includes a guide plate and a defoaming disc, using rotational power to guide the foam to the vortex blades for rupture. This invention can simultaneously achieve bone fragment crushing, fiber depolymerization, and multi-stage filtration and defoaming, significantly improving raw material utilization and purification efficiency.
Owner:SUZHOU YISHUO BIOTECHNOLOGY CO LTD

Preparation method and application of bovine collagen peptide

PendingCN122344609ABovine collagenCollagenan
The application provides a preparation method and application of bovine collagen peptide, and belongs to the technical field of collagen peptide; the preparation method comprises the steps of freeze-thaw-microwave treatment, alkaline hydrolysis, enzyme hydrolysis 1, enzyme hydrolysis 2, enzyme hydrolysis 3, enzyme hydrolysis 4 and antiseptic filtration; in the freeze-thaw-microwave treatment step, bovine skin powder is added into a mixed solution, stirred uniformly, and then soaked for 15-20 min; the mixed solution is placed in a sealed container for freeze-thaw treatment, frozen at-24 to-20 DEG C for 5-6 h, naturally thawed, and then the freeze-thaw treatment is repeated for 1-2 times; the water content is controlled to be 50-52 wt %, and wet material is obtained; the wet material is placed into a microwave device for microwave treatment, and the temperature of the wet material is controlled to be lower than 55 DEG C, so that freeze-thaw-microwave treated bovine skin powder is obtained; the product obtained by the method has high polypeptide content, and when the product is applied to soybeans, potatoes and lettuce, the yield and quality can be effectively improved.

Characteristic collagen peptides of poultry origin and use in the detection of collagen hydrolysates and products thereof

ActiveCN111735891BCollagen hydrolysatesTrypsin
The application discloses poultry-derived characteristic collagen peptides and application thereof in detection of collagen hydrolysate and products thereof, and belongs to the field of detection. The characteristic collagen peptides are Gly-Leu-Val-Gly-Glu-Hyp-Gly-Pro-Ala-Gly-Ala-Lys, Gly-Glu-Gly-Gly-Pro-Ala-Gly-Pro-Ala-Gly-Pro-Ala-Gly-Ala-Arg and Val-Gly-Pro-Ile-Gly-Pro-Ala-Gly-Asn-Arg, and whether poultry-derived components are contained is determined by detecting one or more characteristic collagen peptides. The characteristic collagen peptides are freed by trypsin enzyme cutting on protein components in a sample, and are detected by a liquid chromatograph-mass spectrometer. The method is characteristic and high in sensitivity, and can be used for determination of poultry-derived components in collagen hydrolysate and products thereof.
Owner:BEIJING UNIV OF CHEM TECH +1

Recombinant collagenase high-efficiency expression method and application thereof in preparation of bovine bone collagen peptide

PendingCN122278811AOsteoblastSubstrate concentration
This invention belongs to the field of genetic engineering technology and discloses a high-efficiency expression method for recombinant collagenase and its application in the preparation of bovine bone collagen peptides. The collagenase gene derived from Bacillus sp. HUB-I-004 strain (accession number J9CTX3) was optimized using E. coli-preferred codons. A recombinant expression vector was constructed and transformed into E. coli BL21(DE3). After optimization of induction conditions and Ni-NTA affinity purification, a highly active recombinant collagenase with a specific activity of 231.05 U / mg was obtained. Bovine bone collagen was extracted using a high-temperature, high-pressure method. Bovine bone collagen peptides were prepared under optimal conditions of a substrate concentration of 10 mg / mL, an enzyme addition of 20%, and enzymatic hydrolysis at 37℃ for 8 h, significantly improving peptide yield. The obtained product is mainly composed of small molecule peptides and exhibits significant osteoblast proliferation-promoting activity, making it widely applicable in the preparation of health foods and pharmaceuticals.
Owner:HEFEI UNIV OF TECH

Oral solution containing astaxanthin and method for preparing the same

This invention discloses an oral liquid containing astaxanthin and its preparation method, which is prepared from raw materials comprising the following weight percentages: 0.5%~2% astaxanthin burst beads, 8%~12% collagen peptides, 0.1%~0.3% sodium hyaluronate, 0.01%~2% elastin peptides, 0.01%~0.05% spermidine, 0.005%~0.02% ergothioneine, and 0.001%~0.01% pyrroloquinoline quinone. The astaxanthin burst beads are prepared using astaxanthin oil as the core material and sodium alginate and chitosan as the wall material. This invention, by using astaxanthin burst beads with higher stability and bioavailability in the oral liquid, combined with other ingredients, can improve the user's skin moisture content and elasticity index, reduce wrinkle depth, reduce skin yellowing, and better exert the effects of the oral liquid.
Owner:SERUI HEALTH TECHNOLOGY (GUANGZHOU) CO LTD

Alcohol-containing jelly

The present invention provides a food product that is provided in a solid, tightly packed state that does not impair the flavor, allowing the original taste, flavor, taste, and aroma of the contained alcoholic beverage to spread in the mouth, and also contains a gel-like composition containing health-conscious functional ingredients. [Solution] This is an alcohol-containing jelly that is consumed directly from a tightly filled pouch container. The jelly consists of an alcoholic beverage, functional ingredients, a gelling agent, additives, and water. The functional ingredients are collagen peptide and animal placenta, and the additives include citric acid, flavorings, and sweeteners. The alcoholic beverage content is 10% to 95% by mass of the total alcohol-containing jelly, and the functional ingredients content is 1% to 10% by mass of the total alcohol-containing jelly. The volatilization of ethyl caproate, ethyl caprylate, and ethyl caprate, which are characteristic aroma components of the alcohol-containing jelly, increases by 1.6 to 2.0 times at 37°C compared to 30°C.
Owner:EPIC CORP

A skin care lyophilized powder containing collagen polypeptide and a preparation method thereof

The application relates to the technical field of skin care products, and particularly discloses a skin care freeze-dried powder containing collagen polypeptides and a preparation method thereof. The freeze-dried powder comprises active components, synergistic repair polysaccharides, moisturizers, freeze-drying protectants and preservatives and the like. The core of the freeze-dried powder is that the active components are modified fish collagen peptides which are cross-linked by glutamine transaminase and modified by methyl pyrrolidone silanol ketone, so that the stability and biological activity of the product are significantly improved. Meanwhile, a specific compounded polysaccharide system of beta-glucan, tremella polysaccharide and sodium hyaluronate is adopted in the formula, and a moisturizer prepared by ultrasonic cross-linking of chondroitin sulfate and sodium alginate is adopted, so that the components synergistically act to jointly enhance the repair and moisturizing effects and use skin feeling of the product. The application also provides a corresponding preparation method. Through an optimized freeze-drying process, the problems of traditional freeze-dried powder, such as easy moisture absorption, single effect and poor reconstitution are effectively solved, and finally a skin care freeze-dried powder product with excellent comprehensive performance is obtained.
Owner:澳亚化妆品研究开发(广州)有限公司

A composite truffle protein peptide and a preparation method thereof

PendingCN122096425AFood scienceBiotechnologyOlive leaf
The application provides a compound truffle protein peptide and a preparation method thereof. The compound truffle protein peptide is mainly prepared from the following raw materials in mass fractions: 18-25 parts of cod collagen peptide, 1-2 parts of black truffle peptide, 2-4 parts of Pleurotus eryngii protein peptide, 3-10 parts of olive leaf juice, 2-9 parts of fig juice and 0.5-3 parts of probiotic powder. The compound truffle protein peptide is prepared by scientifically compounding rare fungus active peptide, high-quality structural protein peptide, natural plant antioxidant and intestinal probiotic, so as to achieve the effects of "nourishing skin, enhancing defense, radiating vitality and balancing internal environment".
Owner:GUANGZHOU FOOD & DRUG SOURCE SUPPLY CHAIN CO LTD

Sheepskin and sheep hoof co-production collagen peptide graded degreasing gradient control double enzyme cutting system

PendingCN122278615ABiotechnologyEnzyme digestion
This invention belongs to the field of bioengineering equipment technology, specifically relating to a graded degreasing and gradient-controlled dual-enzyme digestion system for the co-production of collagen peptides from sheepskin and hooves. The system comprises a graded degreasing module and a gradient-controlled dual-enzyme digestion module connected in sequence. The graded degreasing module consists of a first-stage physical degreasing machine with a built-in ultrasonic generator and centrifugal drum, connected in series with a second-stage chemical degreasing tank equipped with a heating jacket, specifically addressing the problem of significant differences in fat distribution and incomplete degreasing in the mixed raw materials of sheepskin and hooves. The gradient-controlled dual-enzyme digestion module consists of a first-stage acidic enzymatic hydrolysis vessel and a second-stage neutral enzymatic hydrolysis vessel equipped with a variable-frequency temperature control jacket and an online pH monitoring device. Gradual temperature programming is achieved through a central PLC control cabinet, ensuring that different proteases are always at near-optimal catalytic temperatures. This system achieves efficient co-production of sheep-derived by-products, significantly improving degreasing thoroughness, collagen peptide conversion rate, and the proportion of small-molecule active peptides, making it suitable for continuous industrial production.
Owner:YAOYE BOSHENG (BEIJING) BIOTECHNOLOGY CO LTD

Additive for preparing high-strength extremely thin lithium copper foil under high current density and production process

The application discloses an additive for preparing high-strength extremely thin lithium battery copper foil under high current density and a production process, and belongs to the technical field of electrolytic copper foil. The additive is prepared by compounding collagen peptide, polydithiodipropyl sulfone sodium, polyethylene glycol-6000, 3-(benzo thiazole-2-methyl) propane sulfonic acid sodium, 2-methyl benzothiazole and hydrochloric acid according to specific contents. The production process comprises the following steps: preparing high-cleanliness copper sulfate electrolyte, mixing the additive with the electrolyte, mixing the additive with the electrolyte under 7000-7500 A / m 2 Electrodeposition foil under high current density. The application uses collagen peptide to replace traditional gelatin, cooperates with sulfur-containing additives and hydrochloric acid, and can significantly improve the tensile strength of copper foil, inhibit apparent defects such as copper powder and burrs, reduce warping and roughness, and can stably produce 4.5-6 mu m high-strength extremely thin lithium battery copper foil, which is suitable for the high energy density demand of power batteries.
Owner:金川集团铜贵股份有限公司

Collagen peptide, collagen peptide salt, polypeptide composition and application thereof

The application discloses a collagen peptide, a collagen peptide salt, a polypeptide composition and application thereof, and belongs to the technical field of active peptide materials. The collagen peptide is a short peptide with an amino acid sequence as shown in SEQ ID NO:1 or a cyclic peptide containing the amino acid sequence as shown in SEQ ID NO:1. The collagen peptide can significantly inhibit tyrosinase activity and significantly inhibit melanin content in cells, thereby achieving a whitening effect.
Owner:GUANGZHOU FANWENHUA COSMETICS CO LTD

A chicken bone collagen polypeptide that promotes calcium absorption, its chelate, preparation method and application

This invention belongs to the field of functional foods and bioactive peptides, specifically relating to a chicken bone collagen peptide that promotes calcium absorption, its chelate, preparation method, and application. This invention employs a rational molecular docking screening strategy, directly screening for the high-affinity peptide DFSLPQPPQ from a chicken bone collagen peptide library by simulating the interaction between peptides and calcium-sensitive receptors. This overcomes the inefficiency of traditional "blind screening" methods, achieving targeted peptide discovery based on mechanisms. The prepared peptide-calcium chelate (DFSFLPQPPQ-Ca) exhibits excellent calcium absorption-promoting performance in the Caco-2 cell model. This invention utilizes chicken bone by-products as raw materials, achieving high-value utilization of resources and providing a precise development path for poultry processing by-products based on clearly defined bioactive peptides, possessing significant industrial promotion value and economic benefits.
Owner:衢州市浙工大生态工业创新研究院

A lutein composition for relieving eye fatigue and its preparation method

ActiveCN121196159BImprove biological activityImproves antioxidant activityFood ingredient as antioxidantSugar food ingredientsGlucuronidasePolyphenol
This invention discloses a lutein composition for relieving eye fatigue and its preparation method, belonging to the field of functional foods. The process involves: reacting phycocyanin and kelp polyphenols to obtain modified phycocyanin; reacting fucoidan and β-glucuronidase to obtain modified fucose; reacting fish collagen peptides and zinc chloride to obtain collagen peptide-zinc chelate; reacting lutein silica cage complex and modified phycocyanin to obtain a first complex; reacting the first complex and modified fucose to obtain a second complex; reacting the second complex, collagen peptide-zinc chelate, and krill oil to obtain a lutein complex; reacting the second complex, collagen peptide-zinc chelate, and krill oil, then adding trehalose to obtain the lutein complex; and finally mixing the lutein complex with maltodextrin to obtain the lutein composition.
Owner:JIANGSU KEMA MEIBAO TECH CO LTD

A bone regeneration formula and preparation method based on bone glue synergy

PendingCN122297798ABone densityEnzymatic hydrolysis
This invention provides a bone regeneration formula based on collagen synergy and its preparation method. The formula uses low-molecular-weight collagen peptides as organic templates and forms hydroxyapatite-like nanostructures through ion-induced mineralization, achieving a tight organic-inorganic interface. The formula can regulate osteoblast differentiation and inhibit osteoclast activity, thereby improving bone density and bone tissue regeneration capacity. The preparation process adopts a low-temperature enzymatic hydrolysis and biomimetic mineralization coupling process to maintain the stability of the active structure. Experimental results show that the formula is superior to conventional formulas in terms of molecular expression, mineralization capacity, and bone metabolism regulation.
Owner:XINHANFANG (GUANGDONG) TECH CO LTD

Alcohol-containing jelly

PCT designated stageWO2026105832A1Alcoholic beverage preparationFood scienceBiotechnologyStar jelly
The purpose of the present invention is to provide a food product provided in a tightly packed state that is solid and does not impair flavor, the food product being such that the savoriness, flavor, taste, and aroma inherent to an incorporated luxury-good alcohol spread in the mouth, and food product containing a gel composition that contains a health-oriented functional component. An alcohol-containing jelly according to the present invention is directly consumed from a tightly packed pouch container, the alcohol-containing jelly being characterized by comprising an alcoholic beverage, a functional component, a gelling agent, an additive, and water, and furthermore being characterized in that: the functional component includes a collagen peptide and an animal placenta; the additive contains citric acid, a flavoring, and a sweetener; the alcoholic beverage content is 10-95 mass% with respect to the entire alcohol-containing jelly; the functional component content is 1-10 mass% with respect to the entire alcohol-containing jelly; and the volatilization amounts of ethyl caproate, ethyl caprylate, and ethyl caprate, which are characteristic aroma components of the alcohol-containing jelly, are 1.6-2.0 times greater at 37°C than at 30°C.
Owner:EPIC CORP

Hydroxyproline-free hydrolyzed collagen peptides and methods of making and using the same

PCT designated stageWO2026136449A1Connective tissue peptidesProsthesisHydroxyprolineMedicine
Provided herein are peptides obtained from hydrolyzed collagen and compositions comprising such. The peptides are from 9 to 100. or 19 to 50 amino acids in length. The peptides are unique from peptides obtained from enzymatically hydrolyzed collagen in that the peptides do not include hydroxyproline. Methods of making the hydroxyproline-free peptides obtained from hydrolyzed collagen, and methods of treatment using the hydroxyproline- free peptides obtained from hydrolyzed collagen are also provided.
Owner:ROCHAL TECHNOLOGIES LLC

Compound nutritional powder with post-exercise recovery function and preparation method thereof

PendingCN122320225ABiotechnologyMuscle tissue
This invention provides a compound nutritional powder with post-exercise recovery function and its preparation method, relating to the field of food processing technology. The preparation method of the compound nutritional powder with post-exercise recovery function includes the following steps: weighing raw materials according to a certain proportion and mixing them evenly to obtain the compound nutritional powder with post-exercise recovery function; the raw materials, by weight, include: 20-50 parts glucose powder, 20-40 parts maltodextrin, 10-25 parts white thorn fruit powder, 2-10 parts soybean peptide powder, and 2-8 parts yak collagen peptide powder. This invention, by compounding glucose powder, maltodextrin, white thorn fruit powder, soybean peptide powder, and yak collagen peptide powder in a specific proportion, combined with vacuum freeze-drying, cell wall breaking, grading and sieving of white thorn fruit powder, and ultraviolet irradiation treatment of some raw materials, achieves the goals of rapid energy supply after exercise, promoting muscle tissue recovery, improving body composition, and enhancing product safety and stability, and has good prospects for the development and application of sports nutrition foods.
Owner:QINGHAI SPORTS SCIENCE INSTITUTE CO LTD

A collagen peptide for increasing bone density and its preparation method

ActiveCN121759562BStable playplay evenlyConnective tissue peptidesSkeletal disorderHydrolysateIncreased Bone Density
This application provides a collagen peptide for increasing bone density and a method for preparing the same. The method includes the following steps: S1: dispersing bone gelatin in water to obtain a bone gelatin solution; S2: adding 0.1-1 mol / L acidic pH adjuster to the bone gelatin solution at a rate of 1-10 mL / min until the turbidity of the system increases by 10%-20% compared to the initial bone gelatin solution, then stopping the addition, allowing it to stand for 10-30 min, and filtering to obtain a bone gelatin supernatant; S3: adding an endopeptide to the bone gelatin supernatant to obtain an enzymatic hydrolysate; S4: post-processing and drying the enzymatic hydrolysate to obtain collagen peptides. This method can increase the mass ratio of low molecular weight peptides in the obtained collagen peptides, resulting in a composition of collagen peptides more suitable for bone metabolism and utilization to increase bone density.
Owner:HUBEI HUGE COLLAGEN II BIOTECHNOLOGY CO LTD

Fish collagen peptides for improving skin moisture and elasticity and a method of preparing the same

ActiveCN121802002BPolyolHydrolysate
The application provides a fish collagen peptide for improving skin moisture and elasticity and a preparation method thereof. The method comprises the following steps: S1: soaking fish scales in water to soften the fish scales, to obtain softened fish scales; S2: soaking the softened fish scales in a pretreatment liquid containing a first polyol and a second polyol, so that the first polyol diffuses into the interlayer of the fish scale collagen, and the second polyol forms a hydration layer on the outer layer of the fish scale collagen, to obtain pretreated fish scales; S3: using an endoprotease to enzymatically hydrolyze the pretreated fish scales, so that fish collagen proteins in the fish scales are hydrolyzed into fish collagen peptides, to obtain an enzymatic hydrolysate; and S4: post-treating and drying the enzymatic hydrolysate to obtain the fish collagen peptide for improving skin moisture and elasticity. Through the above method, the mass proportion of low-molecular-weight polypeptides suitable for the application of improving skin moisture and elasticity in the obtained fish collagen peptide can be increased, and the stability of the molecular weight distribution of the product can be improved.
Owner:HUBEI HUGE COLLAGEN II BIOTECHNOLOGY CO LTD

Collagen peptide multilayer centrifugal purification machine

The utility model belongs to centrifugal purification machine technical field, concretely relates to a collagen peptide multilayer centrifugal purification machine, including the purification machine body, the top of purification machine body is equipped with the drive motor, the top of purification machine body one side still is equipped with the feed inlet of drive motor, the bottom of purification machine body is equipped with the discharge gate, the other end of feed inlet is connected with the adjusting pipe, the outside wall of the one side of adjusting pipe is welded with the sealing pipe, the utility model discloses, when needing to the collagen peptide raw materials in the purification machine body is reduced, at this moment, rotate the rotary lever, the rotary lever will be driven to rotate the driven rod through the connecting rod when rotating, the driven rod will drive the blade on both sides to rotate when rotating, with the change of blade angle, the blade will gradually reduce the inside passage of adjusting pipe, so it can effectively slow down the collagen peptide raw materials into the purification machine body, so that the collagen peptide raw materials in the inside of purification machine body can be kept in the suitable processing range, thereby guaranteeing the collagen peptide promotion effect.
Owner:FOODMATE CO LTD

Hugu active peptide complex and its application in bone health care

This invention discloses a Hu sheep active peptide complex and its application in bone health care. Using healthy Hu sheep bones as raw material, collagen is extracted after defatting and decalcification. This collagen is then enzymatically hydrolyzed with trypsin and alkaline protease, followed by ultrafiltration, desalting, and freeze-drying to obtain Hu sheep bone collagen peptides. These collagen peptides are mixed with pharmaceutical excipients, calcium source compounds, chondroprotective agents, and fat-soluble vitamins. An ethanol-water binder solution containing palmitoyl aspartate diethyl ester and hesperidin-3-O-glucoside is added, and the mixture is granulated, dried, sized, and pressed to obtain the active peptide complex. This complex, through the synergistic effect of its components, can significantly promote osteoblast proliferation and inhibit apoptosis, effectively increasing bone density in osteoporosis model animals. It also exhibits excellent biocompatibility and no cytotoxicity, solving the problems of limited function, insufficient preparation efficiency, and instability of existing single active peptides. This makes it suitable for the development and application of bone health-related nutritional supplements.
Owner:BENGBU COLLEGE

A composition of weight loss optimizers, its method of preparation and use

This invention belongs to the field of functional composition technology, and discloses a weight-loss and body-shaping composition, its preparation method, and its application. The composition, by mass percentage, comprises the following ingredients: 21-25% green coffee, 17-19% white kidney bean extract, 12-18% collagen peptides, 17-25% inactivated compound probiotic powder, and 23-25% mixed fruit and vegetable powder. Green coffee releases the active ingredient chlorogenic acid; white kidney bean extract inhibits α-amylase activity; collagen peptides are easily absorbed and stimulate satiety-related hormones; and the inactivated compound probiotic powder acts as a post-biotic, regulating the intestinal flora environment. This invention achieves its effects through the combined action of three pathways: enhancing satiety, reducing absorption, and regulating metabolism. It can prevent excessive calorie intake, reduce hunger, and simultaneously regulate metabolism. It also increases energy consumption and fat mobilization, provides defecation motivation, regulates intestinal flora balance, and is natural, gentle, and does not harm the human body.
Owner:GUANGDONG ZHONGTAIYI TRADITIONAL CHINESE MEDICINE TECHNOLOGY CO LTD