309 results about "Macroporous resin" patented technology

The invention provides an adsorbent capable of simultaneously adsorbing bilirubin and cytokines and a preparation method and application thereof, and the preparation method comprises the following steps: carrying out suspension polymerization reaction on a styrene monomer and a polyvinyl cross-linking agent in a dispersion medium under the action of a continuous multi-component pore-foaming agent and an initiator to prepare polystyrene-based macroporous resin; carrying out chloromethylation reaction on the polystyrene-based macroporous resin to prepare chlorine balls; carrying out post-crosslinking reaction on the chloromethylated beads to prepare the adsorbent capable of adsorbing bilirubin and cytokines at the same time; the continuous multi-component pore-foaming agent comprises a first pore-foaming agent, a second pore-foaming agent and a third pore-foaming agent of which the solubility parameters are gradually increased in sequence; the temperature of the suspension polymerization reaction is adjusted according to the mass fraction of the polyvinyl cross-linking agent in the monomer mixture and the solubility parameter of the continuous multi-component pore-foaming agent, and the monomer mixture is composed of styrene monomers and the polyvinyl cross-linking agent. The bilirubin and cell factors can be adsorbed at the same time, and the safety of blood purification is improved.

The invention belongs to the technical field of active substance extraction, and discloses a method for extracting boxthorn leaf total flavonoids through an ultrasonic-assisted deep-eutectic solvent and application of the boxthorn leaf total flavonoids. Heating and mixing the hydrogen bond acceptor and the hydrogen bond donor, stirring to be transparent, and adding water to reduce viscosity to obtain the eutectic solvent; mixing the boxthorn leaf powder with a deep-eutectic solvent, performing ultrasonic extraction and centrifugation, and collecting supernate; adsorbing by using macroporous resin, washing and desorbing to obtain an eluent; and performing vacuum freeze drying to constant weight. According to the method disclosed by the invention, the eutectic solvent with low melting point and strong solubility is selected, the flavonoid compounds in the boxthorn leaves are green and efficiently extracted, and the total flavonoid content of the boxthorn leaves obtained by taking the eutectic solvent as an extraction solvent is 123.94 + / -1.04 mg / g and is far higher than the total flavonoid content of the boxthorn leaves obtained by traditional ethanol extraction by 64.60 + / -0.87 mg / g; the method is good in safety, short in time consumption and high in extraction rate.

The present application provides a kind of Radix Polygoni Multiflori active ingredient separation and purification process, belong to plant extraction technical field.The present application separation and purification process includes: Radix Polygoni Multiflori ethanol ultrasonic extraction, activated carbon adsorption, HPD-100 macroporous resin purification, membrane filtration, ultrafiltration, reduced pressure concentration and crystallization step, can efficiently extract Radix Polygoni Multiflori extract with high 5 alpha-reductase inhibitory activity.After compounding with the extract of Euonymus alatus obtained by specific microbial fermentation, the anti-hair loss effect can be significantly enhanced.The in vitro experimental results show that the Radix Polygoni Multiflori extract and the extract of Euonymus alatus both have significant 5 alpha-reductase inhibitory activity.The present application can effectively promote hair growth and improve hair loss, and the effect is close to the positive control drug.The present application process is stable, high in purity, strong in activity, suitable for industrial production, and has good market application prospect.

This invention relates to the field of plant component extraction technology, specifically to a method for efficiently extracting and purifying berberine. The method includes: (1) selecting dried stems of *Radermachera sinensis*, crushing and sieving them to obtain *Radermachera sinensis* powder; (2) weighing the *Radermachera sinensis* powder and mixing it with a 20-30% (w / w) ammonium sulfate solution, then adding a compound enzyme preparation for enzymatic hydrolysis, adding isopropanol to obtain a mixture, extracting the mixture using an ultrasonic-microwave synergistic extraction method, centrifuging the extracted mixture for 10-13 min at 3500-4000 rpm, removing the isopropanol layer by distillation to obtain a crude extract; (3) dissolving the crude extract in water and loading it onto a polar macroporous resin for multiple elutions to obtain berberine. Compared with the prior art, this invention uses an enzyme preparation followed by an aqueous two-phase solvent combined with ultrasonic-microwave extraction technology to promote the maximum release of berberine from *Radermachera sinensis* powder, thereby increasing the yield. Finally, a gradient elution with macroporous resin is used to achieve efficient extraction and purification of berberine.

This invention relates to the field of natural product separation technology, specifically to coumarin compounds isolated from *Hypericum perforatum*, their preparation methods, and applications. The preparation method of these coumarin compounds includes alcohol extraction from *Hypericum perforatum*, followed by macroporous resin adsorption separation and column separation. The coumarin compounds of this invention can be used for anti-inflammatory purposes, exhibiting inhibitory activity against RAW264.7 cells and the expression of TNF-α, IL-1β, and IL-6 proteins.

The invention belongs to the technical field of biological medicine, and particularly relates to a sophora flower extract for inhibiting formation of an oral biofilm and application thereof. According to the method, the sophora flower extract obtained after alcohol extraction is subjected to specific macroporous resin column elution conditions, the sophora flower extract obtained through enrichment has a very excellent effect of inhibiting oral biofilm formation, and further elution is carried out under specific silica gel column conditions, so that the effect of the obtained sophora flower extract is further improved. The inhibition rate of the obtained sophora flower extract is obviously higher than that of sophora flower extracts prepared by traditional alcohol extraction or other processes, and the sophora flower extract has important application value in preparation of products for inhibiting and / or killing oral microorganisms or biological membranes thereof, and can be used for preventing and / or treating dental bacterial diseases including decayed teeth.

The application discloses a method for extracting soybean saponins and soybean oligosaccharides, and belongs to the technical field of natural product extraction. The method comprises the following steps: puffing treatment of soybean meal, wall breaking treatment in a high-voltage electric field; acid precipitation, collection of supernatant; after ultrasonic oscillation of the supernatant, a composite enzyme is added for enzymolysis, and a material liquid after enzymolysis is obtained; after filtration of the material liquid, the material liquid is loaded onto a macroporous resin column for adsorption, and after completion of the adsorption, effluent is collected; the effluent is purified and concentrated to obtain soybean oligosaccharides; an ethanol solution is used to elute the resin column, and eluate is collected; the eluate is recovered by ethanol and dried to obtain soybean saponins; the composite enzyme comprises amylase and beta-glucosidase. The method can significantly improve the extraction rate and purity of soybean saponins and soybean oligosaccharides, the whole process uses water as the main solvent, the consumption of organic solvents and the pollution to the environment are reduced, and the unit process water consumption, unit energy consumption and unit cost are reduced.

The invention relates to an uncaria alkaloid extract as well as a preparation method and application thereof. The method comprises the following steps: heating and leaching uncaria stem and branch powder with acidic ethanol to obtain an acid alcohol leaching solution; carrying out reduced pressure distillation and concentration on the leach liquor to obtain an uncaria total alkaloid extract; removing acid-insoluble substances from the total alkaloid extract, degreasing, adjusting alkali, extracting with chloroform, and recovering a chloroform layer to obtain uncaria crude alkaloid; and dissolving the uncaria crude alkaloid in distilled water, adding into a macroporous resin chromatographic column, adsorbing, flushing, eluting by using a 20% ethanol solution with five column volumes, and collecting the eluent to obtain the uncaria alkaloid extract. The ramulus uncariae cum uncis alkaloid extract PURA1 has the effects of improving the pathological phenotype of the Alzheimer's disease model caenorhabditis elegans and improving the oxidative stress resistance of the caenorhabditis elegans, plays a role in prolonging the service life of the caenorhabditis elegans by regulating and controlling the p38MAPK signal channel of the caenorhabditis elegans, and can be used for preparing the medicine for relieving the Alzheimer's disease and resisting aging.

This invention discloses a Jacaranda flower extract, its preparation method, and its applications, belonging to the field of pharmaceutical technology. The preparation method includes: drying and pulverizing Jacaranda flowers, extracting them by heating and reflux with an ethanol-water solution, concentrating the extract under reduced pressure to obtain a first crude extract; mixing the first crude extract with an aqueous two-phase mixture for extraction, concentrating the upper phase under reduced pressure to obtain a second crude extract; purifying and eluting the second crude extract using a macroporous resin, decolorizing the eluent, and drying to obtain the Jacaranda flower extract. The Jacaranda flower extract obtained by this method has clearly defined active ingredients, exhibits significant photoprotective effects against UVB, and demonstrates significant repair effects after UVB photodamage. It is highly safe and can be used as an active ingredient in skincare products for sun protection.

The utility model discloses a separation and purification device based on macroporous resin, and relates to the technical field of separation and purification, the separation and purification device based on macroporous resin comprises a chromatographic column, the chromatographic column is provided with a chromatographic structure convenient for separation and purification, the chromatographic structure comprises a feed port, a fixed base and a circular truncated cone flow guide ring, the feeding hole is fixedly formed in the upper end part of the chromatographic column, the fixed base is positioned at the lower end part of the chromatographic column, each circular truncated cone flow guide ring is positioned on the inner side wall of the chromatographic column, an adjusting valve is arranged at the lower end part of the chromatographic column, and two column mounting grooves are formed in the upper end part of the feeding hole. The chromatographic column is arranged to purify anthocyanin, the purity of the obtained anthocyanin is higher than that of unpurified anthocyanin, toxic organic solvents are avoided in the whole process, only ethyl alcohol is used, environment friendliness is achieved, resin can be repeatedly used, and the production cost is reduced.

This invention provides an extract of *Elaeocarpus yunnanensis* from Yunnan and its preparation method and application. The preparation method includes the following steps: (1) crushing *Elaeocarpus yunnanensis*, mixing it with an enzyme, and then using a solvent for negative pressure cavitation extraction to obtain a crude extract of *Elaeocarpus yunnanensis*; (2) adsorbing and eluting the crude extract of *Elaeocarpus yunnanensis* obtained in step (1) using a macroporous resin to obtain the *Elaeocarpus yunnanensis* extract. The method provided by this invention can effectively extract active substances from *Elaeocarpus yunnanensis*. The obtained *Elaeocarpus yunnanensis* extract has high geranium content, high total flavonoid content, good antioxidant effect, high hyaluronidase inhibitory activity, good anti-inflammatory effect, and high collagenase activity inhibition rate. The preparation method is economical and environmentally friendly, and the reagents used can be recycled and reused. It can be used as an active substance in health care products and cosmetics.

The application discloses a cassia twig composition and a preparation method and application thereof in preparing medicines for treating gynecological diseases, and relates to the technical field of medicines.The preparation method comprises the following steps: (1) after mixing cassia twig and licorice, alcohol ultrasonic treatment is conducted to obtain alcohol extraction liquid and dregs; (2) after mixing the dregs, white peony root, Chinese date and fresh ginger, water extraction is conducted to obtain water extraction liquid; (3) the alcohol extraction liquid is concentrated and treated by macroporous resin to obtain eluent; and (4) the eluent and the water extraction liquid are combined, concentrated and dried to obtain the cassia twig composition.The macroporous resin treatment is as follows: the volume of the sample liquid is 5BV-10BV, the sample liquid is loaded at a flow rate of 2BV / h-8BV / h, 3BV-7BV of 70%-80% ethanol is used for elution at a flow rate of 1BV / h-5BV / h.The prepared cassia twig composition can better treat cold coagulation and blood stasis dysmenorrhea, and more choices are provided for the treatment of primary dysmenorrhea and other gynecological diseases.

The invention discloses a Chinese chestnut thorn bract hydrolyzed tannin product based on a low-water-activity deep eutectic solvent and a steady-state extraction and refining method of the Chinese chestnut thorn bract hydrolyzed tannin product, and belongs to the technical field of green extraction of natural products. The method comprises the following steps: pretreating chestnut thorn bracts by adopting an antioxidant protective agent, and constructing a low water activity system by taking betaine / L-proline-urea / glycerol-beta-cyclodextrin ternary DES as an extraction solvent and optimizing the molar ratio and the water content; after ultrasonic-assisted extraction, high-purity tannin is obtained through AB-8 macroporous resin purification. According to the method, the steric hindrance of beta-cyclodextrin and a hydrogen bond network are utilized to synergistically inhibit tannin hydrolysis, and ultrasonic enhanced mass transfer is combined, so that the tannin extraction rate is increased by 115% compared with that of a traditional water extraction process, hydrolysis byproducts are reduced by 40% or above, and DES can be recycled at least five times. According to the method, resource utilization of the Chinese chestnut thorn bract waste is achieved, and a new scheme is provided for green steady-state production of the hydrolyzed tannin.

The application discloses Ixeris sonchifolia Hance polysaccharides, a preparation method and application thereof, belongs to the technical field of plant polysaccharides, and provides polysaccharides ISP-1a and ISP-2a, wherein the ISP-1a has a molecular weight of 2086 Da and is composed of seven monosaccharides of mannose, rhamnose, glucuronic acid, glucose, galactose, xylose and arabinose; the ISP-2a has a molecular weight of 1781 Da and is composed of five monosaccharides of mannose, rhamnose, galacturonic acid, xylose and arabinose. The whole grass of Ixeris sonchifolia Hance is subjected to hot water extraction after ethanol degreasing, neutral enzyme + Sevage method is used to remove protein, macroporous resin is used for decolorization, column chromatography elution is carried out, purification is carried out, and two kinds of uniform polysaccharides are obtained after freeze-drying. The polysaccharides ISP-1a and ISP-2a have good antioxidant and lipid-lowering effects, and can be applied to the preparation of food, health products or medicines with antioxidant and lipid-lowering functions.

The application belongs to the technical field of natural product extraction, and provides high-purity curcumin powder and an extraction method thereof. The extraction method of the high-purity curcumin powder comprises the following steps: (1) fresh turmeric is sliced, dried, and then crushed, supercritical CO2 extraction is adopted, and curcumin oil, curcumin powder, and residues are separated; (2) the residues are subjected to fermentation-type ethanol extraction to obtain an alcohol extract; (3) the curcumin powder and the alcohol extract are combined, subjected to macroporous resin adsorption, eluted with ethanol, and then concentrated to obtain a concentrated solution; and (4) the concentrated solution is recrystallized, washed, dried, and then high-purity curcumin crystals are obtained. The extraction method adopts supercritical CO2 fluid extraction coupled with fermentation-type ethanol extraction, and the technology of gradient cooling recrystallization of ethanol and water after macroporous resin adsorption, and the steps are used and operated in cooperation. The product obtained by using the extraction method has high yield and purity, low production cost, small amount of organic solvent, and is suitable for industrial production.

The invention relates to a preparation method and application of modified resin for adsorbing gallium in an acid system, belongs to the technical field of separation and extraction of rare metals, and solves one of the problems of small resin adsorption capacity, poor selectivity and the like in the existing gallium extraction process of a resin adsorption method. Comprising the following steps: cleaning substrate resin which is macroporous resin with weakly alkaline active sites; mixing the cleaned substrate resin and the modifier aqueous solution to obtain a mixed solution, introducing inert gas into a reaction container, adding an initiator into the mixed solution, stirring to carry out a grafting reaction, continuously introducing the inert gas during the reaction, and carrying out solid-liquid separation after the reaction is ended to obtain wet modified resin; and carrying out washing, suction filtration and vacuum drying on the wet modified resin to obtain the finished product modified resin. The total exchange capacity of the resin and the selective adsorption capacity of gallium ions are improved. The modified resin prepared by the method has large adsorption capacity on gallium in an acid system.

The invention discloses a method for separating and purifying total flavonoids from abelmoschus manihot flowers. The method comprises the following steps: 1) an extraction process; (2) pretreating the feed liquid; 3) a flocculation process; 4) macroporous adsorption resin extraction; (5) dealcoholization; and 6) drying. The method comprises the following steps: extracting an abelmoschus manihot flower material with an ethanol salt solution, filtering, taking a treated soak solution, concentrating, dealcoholizing, diluting with water, and adding sodium lignin sulfonate and chitosan for flocculation reaction to obtain a column loading solution; selecting macroporous resin for separation and purification, carrying out rotary evaporation on the desorbed mixed solution to recover ethanol, and carrying out spray drying or freeze-drying to obtain a high-content flavone product; extraction and separation are carried out by utilizing the property of flavone, an extraction and separation method with high content and high yield is obtained, the use of a large amount of organic solvents is reduced, and environmental protection is facilitated.

The invention belongs to the technical field of hydrochloric acid recovery, and discloses a benzene chlorination process byproduct hydrochloric acid impurity removal refining system and method.The method comprises the steps that sodium sulfite is added into hydrochloric acid to remove free chlorine, organic matter in hydrochloric acid is adsorbed through polystyrene-based macroporous resin, iron ions are adsorbed through amino-containing ion exchange resin, and the hydrochloric acid is recycled; hydrochloric acid is fed into a desorption tower for heating desorption, obtained pure hydrogen chloride gas is fed into an absorption tower for secondary absorption, and absorbed water is ultrapure water. According to the method, a combined process of resin adsorption and hydrogen chloride desorption and reabsorption is adopted, volatile impurities are firstly removed, then non-volatile inorganic impurities are deeply adsorbed, the labor division is clear, the efficiency is high, the final product is clear and transparent, the quality is stable, the economic benefit is remarkable, low-value and difficult-to-treat waste acid is converted into high-value commodity hydrochloric acid, waste is turned into wealth, and the method is suitable for industrial production. And remarkable economic benefits are created, and the environmental protection pressure is reduced.

The invention belongs to the technical field of adsorption materials, and particularly relates to a solid amine material for carbon dioxide adsorption and a preparation method thereof. The solid amine material is polystyrene macroporous resin with cross-linked amino groups, and the preparation method comprises the following steps: taking primary amine type polystyrene macroporous resin as a base material, cross-linking the amino groups on the base material by using a cross-linking agent, and then cleaning and drying to obtain the solid amine material. As crosslinking is carried out among amino groups, the solid amine material has better structural stability than primary amine type polystyrene macroporous resin serving as a base material, the material is not prone to gelation, circulation attenuation for carbon dioxide adsorption is remarkably reduced, and the service life is longer.

The invention provides a method for simultaneously separating three flavone monomeric compounds from glycyrrhiza glabra, and belongs to the technical field of compound separation. The method comprises the following steps: mixing glycyrrhiza glabra powder with ethanol, carrying out supercritical CO2 extraction, carrying out spin-drying, mixing an extract and ethanol, carrying out ultrasonic dissolution and standing in sequence, adding a supernatant fraction into a macroporous resin chromatographic column from the upper part, eluting the macroporous resin chromatographic column with ethanol, and carrying out vacuum concentration to obtain the glycyrrhiza glabra extract. Desolventizing the eluted fraction to obtain a main fraction extract; mixing the main fraction extract with a recrystallization solvent, and standing the mixed solution to obtain a solid 1 and a filtrate 1; standing the filtrate 1 to obtain a solid 2 and filtrate 2; standing the filtrate 2 to obtain a solid 3; according to the method, the extraction efficiency is high, the supercritical CO2 has low viscosity, high diffusivity, high mass transfer rate, strong permeability and relatively short extraction time; according to the method disclosed by the invention, three kinds of glycyrrhizic flavonoid compounds, namely glabridin, glabridin and isopentenyl coumestrol, are successfully obtained.

This invention relates to a highly active effective fraction of the Epiglottis-Clearing Decoction and its application in the preparation of antitussive drug compositions, belonging to the field of traditional Chinese medicine extract technology. The effective fraction contains hydroxysaffron yellow A, paeoniflorin, naringin, and neohesperidin, with the total content of these four components not less than 20% of the total mass of the effective fraction. The effective fraction of this invention is prepared by purification with macroporous resin. Compared with the freeze-dried powder of the traditional Epiglottis-Clearing Decoction, the total content of the four active ingredients is increased from 3.32% to 20.87%, achieving a more than 6-fold high-efficiency enrichment. Animal pharmacodynamic experiments show that the antitussive effect of a low dose (275.5 mg / kg) of this effective fraction is comparable to that of the freeze-dried powder of the original decoction (1928 mg / kg), reducing the dosage to about 1 / 7 of the original formula, demonstrating a significant "synergistic effect with reduced dosage" technical effect. The effective active ingredients provided by this invention have a clear content and stable quality, and can be made into modern preparations such as tablets, capsules or granules, solving the problems of large volume, inaccurate dosage and poor patient compliance of traditional decoctions.

The invention discloses a preparation process of an ovateleaf holly bark total saponin bulk drug, and particularly relates to the field of traditional Chinese medicine extraction and purification, the preparation process comprises the following steps: S1, extraction: crushing an ovateleaf holly bark medicinal material, and carrying out reflux extraction by using an ethanol aqueous solution as a solvent to obtain an ovateleaf holly bark crude extract; and S2, purification: carrying out solid-liquid separation on the crude ovateleaf holly bark extract, and purifying the filtrate through a recrystallization process and a macroporous resin adsorption process in sequence to obtain the ovateleaf holly bark total saponin bulk drug. According to the invention, an effective component group of ovateleaf holly bark for treating ulcerative colitis is taken as a target, the effective component group comprises syringin, pedunculoside and ziyuglycoside II, and a complete extraction-purification integrated process is constructed; through an orthogonal test, a comprehensive weighted scoring method is combined, and extraction parameters are scientifically optimized, so that the transfer rate of the three functional components is maximized, the extraction efficiency is high, and the pertinence is extremely high.

The invention discloses a method for increasing the yield of monascus pigment through liquid fermentation, the monascus pigment is obtained through spore culture, seed culture, liquid fermentation and monascus pigment extraction by taking monascus as a production strain, and macroporous resin is added into a fermentation culture medium. According to the method, the yield of liquid fermentation of the monascus pigment can be greatly increased, the monascus pigment is concentrated in precipitates, namely resin and hyphae after solid-liquid separation is carried out on the fermentation product, a water phase of fermentation liquor does not contain pigment, separation and extraction of downstream fermentation products and treatment of fermentation waste liquor are facilitated, and the method has good market prospects and market value.

According to the folium artemisiae argyi extract, the preparation method thereof and the application of the folium artemisiae argyi extract in growth promotion, the folium artemisiae argyi extract required by a plant biostimulant comes from folium artemisiae argyi, the folium artemisiae argyi extract has the advantages of being rich in source, easy to extract and the like, green and sustainable agricultural development is facilitated, and a new scheme is provided for yield increase of crops. According to the extract, leaves and stems of traditional Chinese medicine folium artemisiae argyi serve as raw materials and are subjected to two times of ultrasonic extraction (absolute ethyl alcohol), filtrate is combined, then a crude extract is prepared, a purified component is a 60% ethanol component obtained by separating the crude extract through macroporous resin, the purified component mainly comprises a flavonoid component, and the content of eupatilin is the highest. The plant height, leaf length and fresh weight of rice, pakchoi, cotton and soybean are all improved after the fertilizer is applied according to the application mode mentioned in the invention.

The invention discloses an extraction and purification method and application of malus toringoides leaf and leaf tea polyphenol, and belongs to the field of separation and application of natural plant products. The method comprises the following steps: mixing malus toringoides fruit and leaf dry tea powder with ethanol according to a set material-to-liquid ratio, and carrying out ultrasonic treatment on the mixed solution to obtain a malus toringoides fruit and leaf tea polyphenol crude extract; adding the malus toringoides leaf and leaf polyphenol crude extract into a chromatographic column filled with macroporous resin, and performing elution adsorption with an ethanol solution after adsorption equilibrium is achieved; and recovering the eluent, and freeze-drying to obtain the purified malus toringoides leaf and leaf tea polyphenol extract. The malus toringoides leaf and leaf tea polyphenol extract obtained by the invention has strong free radical scavenging capacity, can effectively inhibit active oxygen of HepG2 cells, and can be used for researching, developing and preparing antioxidant functional foods and medicines.

The application discloses a method for synthesizing catalase nanocapsules based on gas-liquid two-phase flow microfluidic technology and application. Nitrogen is used as a gas phase, and a liquid phase containing acrylated catalase, a monomer mixture and a crosslinking agent is used to form Taylor flow in a microfluidic chip. The internal vortex of the gas-liquid interface is used to enhance the mixing efficiency, and in-situ radical polymerization on the surface of the enzyme is realized. By screening six microfluidic chips with different structures, the geometric parameters of the chip and the hydrodynamic conditions are optimized, and the particle size uniformity and enzyme activity retention rate of the nanocapsules are significantly improved. The application also discloses a continuous flow reactor system for loading the obtained nanocapsules on macroporous resin microspheres to construct a continuous flow reactor system, and the system is used for efficient degradation of hydrogen peroxide in semiconductor wastewater. The method has the advantages of high mixing efficiency, mild reaction conditions, continuous production and the like, the obtained nanocapsules have the advantages of narrow particle size distribution, high enzyme activity and good stability, and are suitable for the field of industrial wastewater treatment.

This invention provides a method for separating and purifying anthocyanins using a continuous macroporous resin chromatography system, belonging to the field of separation and purification technology. This invention utilizes a continuous macroporous resin chromatography system for the separation and purification of anthocyanins. The sample injection zone, water washing zone, ethanol stripping zone, resin regeneration zone, and water wash solution recovery zone do not interfere with each other and can operate simultaneously at room temperature, avoiding anthocyanin decomposition and significantly improving the separation and purification efficiency. It enables continuous, large-scale separation and purification of anthocyanins, achieving good separation and purification effects, high purity enhancement, and high yield. This invention uses ethanol and water as eluents, which are non-destructive to the compounds to be analyzed and purified, exhibiting low reactivity and toxicity, and are abundant and inexpensive solvents. Furthermore, this invention allows for the rapid processing of large quantities of anthocyanin samples while recovering ethanol, achieving greater efficiency with lower costs.

The invention relates to the technical field of traditional Chinese medicine compositions, and provides a traditional Chinese medicine composition for removing acnes, which is prepared from the following components in parts by weight: 1-2 parts of honeysuckle stem extract, 0.3-0.8 part of fructus forsythiae extract, 2-4 parts of radix scutellariae extract, 0.5-3.5 parts of cortex magnoliae officinalis extract and 1-5 parts of astragalus complanatus extract. The preparation method of the fructus forsythiae extract comprises the following steps: crushing fructus forsythiae, performing steam explosion treatment to obtain pretreated fructus forsythiae, adding water, adding biological compound enzyme, performing enzymolysis, filtering and performing enzyme deactivation to obtain filtrate; enabling the filtrate to pass through macroporous resin, washing with water, carrying out first elution to obtain a solution I, and carrying out second elution to obtain a solution II; performing post-treatment on the solution I to obtain forsythiaside; performing post-treatment on the solution II to obtain forsythin; the biological compound enzyme comprises alpha-galactosidase, lipase and xylanase. Through the technical scheme, the problem of low extraction rate of forsythin and forsythiaside in fructus forsythiae in the prior art is solved.

The invention discloses gallium ion imprinted amidoxime-based macroporous resin as well as a preparation method and application thereof, and belongs to the technical field of functional polymer materials and separation. The method comprises the following steps: pre-assembling a gallium trichloride template and monomers such as acrylonitrile, generating monodisperse liquid drops by utilizing a microfluidic technology, polymerizing by combining ultraviolet light, eluting the template by hydrochloric acid, and performing amidoximation modification by a hydroxylamine hydrochloride alkaline solution, thereby obtaining the resin. The resin is a monodisperse spherical microsphere, has a macroporous structure, has high selective recognition capability and high adsorption capacity on gallium ions, is fast in adsorption kinetics and good in regeneration performance, and is suitable for selectively separating or enriching gallium ions from a complex solution system.

This invention relates to the fields of petrochemicals and environmental protection, specifically disclosing a method for adsorbing ethylene glycol from carbonate aqueous solutions. By using a specific non-polar macroporous resin as the adsorbent and combining it with appropriate adsorption conditions, the adsorption efficiency of non-polar macroporous resins on ethylene glycol in carbonate aqueous solutions can be improved.