11 results about "Surfactin" patented technology

The present invention belongs to the technical field of daily chemical industry, and specifically relates to an emulsion and a preparation method thereof. The emulsion provided by the present invention comprises an emulsifier, glycerol, an oil-phase active substance, pentaerythrityl tetra(ethylhexanoate) and water; wherein the emulsifier is a lipopeptide; the weight percentage of the lipopeptide relative to glycerol is not less than 3%; the weight ratio of the oil-phase active substance to pentaerythrityl tetra(ethylhexanoate) is 1:(3 to 13); the ratio of the total weight of the lipopeptide and glycerol to the total weight of the oil-phase active substance and pentaerythrityl tetra(ethylhexanoate) is 1:(3 to 10); and the ratio of the total weight of the lipopeptide, glycerol, oil-phase active substance and pentaerythrityl tetra(ethylhexanoate) to the weight of water is 1:(1 to 4). By compounding sodium surfactin with glycerol and pentaerythrityl tetra(ethylhexanoate), the emulsion can effectively inhibit the diffusion of the oil-phase active substance at an emulsion interface, reduce the oxidative degradation of the oil-phase active substance, and greatly prolong the effective action time of the oil-phase active substance in the emulsion.

The application provides a nanoemulsion and a preparation method and application thereof. The total amount of raw materials for preparing the nanoemulsion is 100%, and the raw materials include the following components: 1-40% of a composite surfactant, 1-25% of an oil phase, 1-30% of a co-surfactant, and the balance of a water phase; wherein the mass of the composite surfactant is 100%, and the composite surfactant includes the following components: 5-25% of a biological surfactant, 35-65% of a fatty alcohol polyoxyethylene ether surfactant, 1-20% of dodecyl benzene sulfonic acid and / or sodium salt thereof, 1-20% of oleic acid, and 1-5% of citric acid; the biological surfactant includes one or more than two combinations of sophorolipid, rhamnolipid, trehalose lipid, surfactin, alkyl polyglycoside, phosphatidylcholine, amino acid lipid, saponin, phospholipid, or derivatives thereof; and the average particle size of the emulsion droplets in the nanoemulsion is 1.5-5 nm. The nanoemulsion has excellent recovery performance.

A composition for caring for and / or making up keratin materials, comprising: (i) at least one surfactant selected from surfactins, their derivatives and mixtures thereof; (ii) at least one alkyl polyglucoside; and (iii) at least 12 wt.% of at least one fatty compound, relative to the total weight of the composition is provided. A non-therapeutic method for caring for and / or making up keratin materials is also provided.

This invention discloses a core-shell microneedle with both antibacterial and exudate-absorbing properties, and its preparation method, belonging to the field of microneedle drug delivery systems and acne treatment technology. The microneedle comprises: a core layer containing an exudate-absorbing component for absorbing exudate; and a shell layer covering the core layer, containing a microenvironment-responsive drug delivery unit and antibacterial nanoparticles loaded within the drug delivery unit. The drug delivery unit responds to the microenvironment of the acne lesion by releasing the antibacterial nanoparticles. This invention combines baicalein and surfactant into nanoparticles, loaded into a ROS-responsive shell layer formed by TSPBA and polyvinyl alcohol. Sodium polyglutamate is introduced into the core layer as an exudate-absorbing component. The core-shell microneedle is prepared by a two-step centrifugation method. This invention solves the problems of poor drug permeability, uncontrollable release, and exudate affecting treatment efficacy in traditional acne treatments. It achieves targeted drug release and exudate adsorption synergistic effects on acne lesions, improves drug bioavailability, reduces systemic side effects, and is suitable for the treatment of acne, especially inflammatory and purulent acne.

SKINCARE AND / OR MAKE-UP COMPOSITION FOR KERATINOUS MATERIALS The present invention relates to a skincare and / or makeup composition for keratinous materials, comprising: (i) at least one surfactant selected from surfactins, their derivatives, and mixtures thereof; (ii) at least 2% by weight of at least one wax with a melting point of at least 60°C, relative to the total weight of the composition; and (iii) at least one paste-like compound. The present invention also relates to a non-therapeutic method for skincare and / or makeup of keratinous materials. Figure for the abstract: none

The present application relates to the field of genetic engineering and bioengineering, and particularly relates to a genetically engineered surfactin-producing bacterium and application thereof.The genome of the genetically engineered bacterium comprises the following: an expression frame of T7 RNA polymerase; an expression frame of a surfactin synthesis gene cluster srfAABCD; and an expression frame of a long-chain fatty acid-coenzyme A ligase gene lcfA; the expression frame of the surfactin synthesis gene cluster srfAABCD and the expression frame of the long-chain fatty acid-coenzyme A ligase gene lcfA further comprise a T7 promoter.The present application realizes efficient synthesis of surfactin by Bacillus subtilis, and the final shake flask yield reaches more than 19.3 g / L, which has great industrial application potential.

The application belongs to the technical field of fresh-keeping materials, and particularly relates to a Surfactin composite film, a preparation method thereof and application of the Surfactin composite film in fruit and vegetable fresh-keeping, the preparation method comprising the following steps: preparing polyvinyl alcohol and chitosan into solutions respectively, mixing the two solutions, adding glycerol and citric acid, heating and stirring to make the system uniform, and obtaining a mixed solution; adding Surfactin and mixing uniformly, then casting and drying to obtain the Surfactin composite film. The composite film has good antibacterial performance and ultraviolet blocking performance, can effectively delay water loss of fresh-cut apples and inhibit quality deterioration, and has important application value and prospect in fruit and vegetable fresh-keeping packaging.

SKINCARE AND / OR MAKE-UP COMPOSITION FOR KERATINOUS MATERIALS The present invention relates to a skincare and / or makeup composition for keratinous materials comprising: (i) at least one surfactant selected from surfactins, their derivatives, and mixtures thereof; (ii) at least one alkyl polyglucoside; and (iii) at least 12% by weight of at least one fatty compound, relative to the total weight of the composition. The present invention also relates to a non-therapeutic method for skincare and / or makeup of keratinous materials. Figure for the abstract: none

This invention discloses a method for constructing and fermenting a strain of Bacillus subtilis to enhance anaerobic expression and improve surfactant synthesis. First, a chassis strain 158T7P is obtained by integrating and inserting an inducible transcriptional T7 RNA polymerase expression gene into the genome of Bacillus subtilis 158. Further genetic manipulation of this Bacillus subtilis, through systematic substitution of the T7 promoter, yields strain 158T7P-srf, capable of producing surfactant in high-density microaerobic fermentation. Specifically, this involves using homologous recombination to transform the operon of Bacillus subtilis 158... resde The starter and control sfp The promoters for transcription of the gene and the srfABCD operon were replaced with T7 promoters. The obtained Bacillus subtilis 158T7P-Srf was able to achieve high production of surfactant using inexpensive carbon sources such as brown sugar as substrates. In the fermentation experiment, the surfactant production reached a maximum of 36.58 g / L.

A composition for caring for and / or making up keratin materials, comprising: (i) at least one surfactant selected from surfactins, their derivatives and mixtures thereof; (ii) at least 2 wt.% of at least one wax with a melting point of at least 60℃, relative to the total weight of the composition; and (iii) at least one pasty compound is provided. A non-therapeutic method for caring for and / or making up keratin materials is also provided.

This disclosure relates to a method for producing a composition comprising one or more lipopeptides, such as fentanyl, ituronin, or surfactant, the method comprising steps a) initiating a fermentation process by introducing bacteria belonging to the genus *Bacillus* into a suitable fermentation medium; b) maintaining a low dissolved oxygen (DO) level in the fermentation medium; and c) performing a recovery step to recover the one or more lipopeptides, thereby providing a composition comprising the one or more lipopeptides, wherein the low dissolved oxygen level in step b) is preferably a dissolved oxygen level in the range of 5% to 35%. The composition obtained by the method and its use for the prevention, control, or improvement of infections in plants caused by fungal or bacterial pathogens are also claimed.