391 results about "Phenazine" patented technology

Dihydrophenazines and bis(dihydrophenazines) are prepared in high yield under commercially viable reaction conditions by reacting a catechol with a 1,2-diaminoaryl compound, wherein either the catechol or the 1,2-diaminoaryl compound is provided in at least 50% molar stoichiometric excess. The product may be oxidized to the corresponding phenazine, but is preferably derivatized at one or both of the 5,10-positions to form a monosubstituted or disubstituted dihydrophenazine or bis(dihydrophenazine). Most preferably, 5,10-dialkyl-5,10-dihydrophenazines are prepared starting from catechol and 1,2-diaminoaryl compound in a one pot synthesis. The products are useful as dyes, and in particular as chromophores in electrochromic systems.

Disclosed herein are phenazine-3-one and phenothiazine-3-one derivative compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging.

The invention discloses a gene engineering bacterial strain used for producing phenazine-1-methanamide and its purpose; which is characterized in that knockout of psrA or rpeA gene in Pseudomonas chlororaphis HT66(Pseudomonas chlororaphis HT66) CCTCC NO: M 2013467 genome is carried out. According to the invention, a strain of Pseudomonas chlororaphis is performed with seed culture, fermentation, extraction, concentration and crystallization to obtain phenazine-1-methanamide with purity of more than 96%. After the deletion of psrA and rpeA gene in the bacterium genome, the fermentation output of phenazine-1-methanamide can reach as high as 1800ppm. The agar plate bacteriostasis tests found that phenazine-1-methanamide has obvious inhibition effect on common plant pathogenic fungi such as Rhizoctonia solani, fusarium oxysporum, pythium wltmum and Stevia Septoria, has good stability and activity, and has good application prospect.

Disclosed herein are phenazine-3-one and phenothiazine-3-one derivative compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging.

The invention relates to a method for preparing bactericide by using derivative bacterial of growth promoting antagonist bacterial M18, preparing fermentation liquor with high concentration of under phenazine-1-carboxyl acid and pyoluteorin under optimized culture medium and condition by using derivative bacterial M18G and M18R of growth promoting antagonist bacterial M18, preparing the fermentation liquor M18G and M18R into dry powder, double crossing physically the phenazine-1-carboxyl acid in M18G powder and pyoluteorin in M18R according to the weight ratio of 90%-10% and 10%-90%, and finally getting bactericide of high efficiency for preventing plant disease. Compared with current technology, the bactericide provided in this invention is wet powder taking metabolite of microorgsanism as active element but not live bacterial agent, as a result of which the product is characterized by high stability, not easy to be influenced by environment and better prevention and curing effect for multiple plant disease under low consumption.

Provided is a glucose sensor that is capable of measuring a glucose concentration even in the case where Aspergillus oryzae type FAD-GDH (flavin adenine dinucleotide-glucose dehyrogenase) and a ruthenium compound are used in combination. The glucose sensor includes an insulative substrate, an electrode system having a working electrode and a counter electrode provided on the substrate, and a reagent layer provided on the electrode system, wherein the reagent layer contains Aspergillus oryzae type FAD-GDH, a ruthenium compound, and PMS (phenazine methosulfate).

The invention discloses a thermal activation delayed fluorescence material based on a dibenzophenazine derivative as well as a preparation method and application of the thermal activation delayed fluorescence material, and belongs to the technical field of organic photoelectric materials and devices. The structural formula of the material is shown as a formula (I), in the formula (I), R1 is phenoxazinyl, phenothiazinyl or dimethyl acridinyl, R1' is phenoxazinyl, phenothiazinyl or dimethyl acridinyl, R1 '' is phenoxazinyl, phenothiazinyl or dimethyl acridinyl, and R2 is H, phenoxazinyl, phenothiazinyl or dimethyl acridinyl. The material provided by the invention has the advantages that the electron acceptor and the electron donor unit show a highly distorted rigid structure, 100% theoretical internal quantum efficiency can be realized, the fluorescence quantum yield is high, a guarantee is provided for a high-efficiency long-waveband OLED device, and the like. And a polysubstitution mode is adopted, so that red shift of molecular emission wavelength is facilitated, long-waveband luminescence is realized, and a guarantee is provided for an efficient long-waveband OLED device.

The invention relates to a synthesis method of a receptor molecule used for identifying H2PO4<-> and Fe<3+>. The receptor molecule treats a naphthalene ring as a fluorescence signal report group, uses an oxygen atom in a hydroxy group and nitrogen atoms in an imidazolyl group as binding sites of Fe<3+>, and has a strong complexing ability on Fe<3+>, H2PO4<-> and Fe<3+> can form Fe(H2PO4)3 inorganic salt, so Fe<3+> and H2PO4<-> can be continuously fluorescently identified. Results of fluorescence titration experiments show that the receptor has a high detection sensitivity to each of Fe<3+> and H2PO4<->, and the lowest detectable limits reach 0.29ppm and 0.19ppm respectively. The invention also relates to a receptor molecule supported colorimetric test paper. The colorimetric test paper can conveniently and fast fluorescently detect Fe<3+> and H2PO4<->, and has a very good application prospect in the detection fields of Fe<3+> and H2PO4<->.

The invention provides a ruthenium (II)-polypyridine complex. For the ruthenium (II)-polypyridine complex, bipyridyl (bpy) or phenanthroline hydrate (phen) is used as an ancillary ligand, and dipyridine[3,2-a:2',3'-c]phenazine-11,12-imidazole (dppzi) is used as a main ligand. The preparation method comprises the following steps: preparing 5,6-dinitrobenzimidazole from 5,6-nitrobenzimidazole; reducing 5,6-dinitrobenzimidazole into 5,6-diaminobenzimidazole by using hydrazine hydrate and palladium / carbon; preparing dppzi from phenanthroline hydrate-5,6-dione and 5,6-diaminobenzimidazole and preparing cis-[Ru(bpy)2Cl2].2H2O from ruthenium trichloride, bpy and lithium chloride; preparing cis-[Ru(phen)2Cl2].3H2O from ruthenium trichloride, phen and lithium chloride; carrying out a heating reflux reaction on dppzi and cis-[Ru(bpy)2Cl2].2H2O or cis-[Ru(phen)2Cl2].3H2O under the protection of argon, carrying out cooling, adding ammonium hexafluorophosphate, allowing precipitate to deposit and carrying out filtration and column chromatography so as to obtain a target product. The ruthenium (II)-polypyridine complex provided in the invention can be used as an optical switch for G-quadruplex DNA molecules.

The invention relates to a phenoxazine dye and a photoelectric converter using the dye, and belongs to the technology field of phenoxazine dyes. The technical proposal is that: the chemical structure of the dye contains substituted phenoxazine and the derivative thereof as electron donors and different conjugated groups as bridging chains, wherein one end of the bridging chains are connected with different electron-withdrawing groups. An electron-donating group on a nitrogen atom and lone-pair electrons on an oxygen atom interact with a chromophoric conjugated system, thereby resulting in more easier charge transfer of the excited state of molecules and generating unique photoelectric property. The phenoxazine dye has good application performance in dye-sensitized solar cells, and can replace expensive noble metal photosensitive dye in dye-sensitized solar cells.

The invention provides an organic electroluminescent compound of a phenazine derivative. The organic electroluminescent compound is a compound shown in a structural formula I. The organic electroluminescent compound can be used for preparing an organic electroluminescent apparatus. The formula is shown in the description.

The invention discloses a genetic engineering strain for producing phenazine-1-carboxylic acid, which is produced by taking pseudomonas chlororaphis as a culture, as well as application of the genetic engineering strain; the genetic engineering strain is obtained by knocking out a phzH gene in pseudomonas chlororaphis genome. The genetic engineering strain for producing phenazine-1-carboxylic acid is finally prepared by deleting the phzH gene in the genome of the strain by virtue of insertion mutation or marker-less deletion from pseudomonas chlororaphis HT66 CCTCC NO: M2013467 which can naturally secrete phenazine-1-formamide as well as derivatives of the pseudomonas chlororaphis so as to convert a secondary metabolite from the phenazine-1-formamide into the phenazine-1-carboxylic acid. The invention also discloses a preparation method and a detection method of the fungicide.

The invention provides a method for preparing a phenazine compound by catalyzing o-halogeno aniline in a pure water phase. By using a water soluble coordination compound as a catalyst, the phenazine compound is prepared by efficiently catalyzing the o-halogeno aniline in the pure water phase. The invention provides a novel method for preparing the phenazine compound, which has the advantages of environment friendliness, simplicity and convenience for operation, safety, low price and high efficiency. Compared with the prior art, the method provided by the invention is not only applicable to a large quantity of functional groups but also has the advantages of simplicity in operation, high yield, single product, convenience for separation and purification, safety, low price and less pollution. The catalyst is as follows: (1) an in-situ catalyst formed by a copper salt and 2-pyridine carboxylic acid, and (2) a coordination compound.

The invention relates to an iridium complex provided with novel main ligands and using acetylacetone or dibenzoyl methane as an auxiliary ligand. The main ligands in iridium complex molecules are 2,3-diphenyl quinoxaline, 2,3-diphenyl pyridine[2,3-b]pyrazine, 2,3-diphenyl pyrazine[2,3-b]pyrazine, dibenzo[a,c]phenazine and a bipyridino[3,2-a: 2', 3'-c] phenazine derivative. The novel iridium complex has the advantages of high luminous efficiency, stable chemical properties, easy sublimation purification and the like, and the device performance is also excellent. By modifying molecular structures of the ligands, the luminous intensity and efficiency of the complex can be adjusted within a red light wavelength range, and convenience is provided for design and production of organic electroluminescent displays and lighting sources.

The invention discloses an orange red light thermal activated delay fluorescent material which is 3,6,11-tri(9,9-dimethyl acridine-10(9H)-yl)-dibenzo[a,c] phenazine (3DMAC-BP). The fluorescent material has a rigid large-plane twisted structure and a remarkable internal charge transfer (ICT) effect, has an organic red thermal activated delay fluorescence property (TADF), a high fluorescence quantumyield (PLQY) and excellent thermal stability, and is simple in synthesis preparation steps, and raw materials are easy to obtain, synthesis and purification processes are simple, the yield is high and large-scale synthesis and preparation can be achieved. The organic electroluminescence device based on the material is capable of emitting orange red fluorescence (lambda=606nm), the external quantum efficiency EQE of the device is as high as 22%, and the device has the advantages of being low in driving voltage, good in light emission stability, and the like, and has good application prospectsin fields such as lighting, panel display, sensation, night vision, bioimaging and the like.

The invention provides a method for synthesizing phenazine-1-carboxylic acid. The method comprises the steps of carrying out bromination reaction on 1-methyl-phenazine as a starting material and N-bromosuccinimide in the presence of benzoyl peroxide as a catalyst to produce 1-bromomethylphenazine, further hydrolyzing 1-brominemethylphenazine to obtain 1-hydroxymethyl phenazine and finally oxidizing to obtain phenazine-1-carboxylic acid, namely, shenqinmycin. According to the method disclosed by the invention, disadvantages of low yield, relatively high production cost, high treatment cost of three wastes and the like are solved, and the method for synthesizing phenazine-1-carboxylic acid with the advantages of simple synthetic steps, high yield, low cost and environment friendliness is provided.

The preparation process of Ru(II)-polypyridine complex includes the following steps: preparing 1,10-phenanthroline-5,6-diquinone, pyridine [3, 2-a:2', 3'-c] phenazine as ligand I, and 7,8-dimethyl pyridine [3, 2-a: 2', 3'-c] phenazine as ligand II, Ru(bipy)2Cl2.2H2O (bipy=2, 2'-dipyridyl) as precursor I and Ru(phen)2Cl2.2H2O as precursor II; adding certain amount of Ru(bipy)2Cl2.2H2O / Ru(phen)2Cl2.2H2O, ligand I / ligand II, and mixture liquid of methanol and water, heating reflux for certain time, heating to concentrate, adding water and boiling, freezing, adding sodium tetrafluoborate, filtering and separating out precipitate, re-crystallization in alcohol, and stoving under infrared lamp to obtain the Ru(II)-polypyridine complex. The Ru(II)-polypyridine complex is used as nucleic acid recognizing probe for the analysis and detection of nucleic acid, and has high stability, high sensitivity, high selectivity and other advantages.

The invention relates to a diquinoxaline phenazine derivative and a synthesis method and application thereof and belongs to the field of synthesis of electrode materials for lithium ion batteries. Thesynthesis method comprises that a 2, 3-diamino-1, 4-phenyl derivative and cyclohexanone decahydrate are added into a reactor in an inert protective atmosphere and are dissolved in an organic solvent,the reaction mixture is continuously stirred in a reflux state for 6-48h, after the reaction, heating is stopped, and water is added into the reaction system so that solid products are precipitated.The diquinoxaline phenazine derivative has a broad application prospect in the field of lithium ion battery electrode materials.

The invention provides an electrochemical CO2 capture device and methods employing proton-coupled redox active species, e.g., a quinone, phenazine, alloxazine, isoalloxazine, or polyoxometalate, whose protonation and deprotonation can be controlled electrochemically to modify the pH of an aqueous solution or aqueous suspension. This change in pH can be used to sequester and release CO2. The CO2 capture device can be used to sequester gaseous CO2 from a point source, such as flue gas, or from ambient air.

The invention discloses an electroplating copper solution and electroplating method for a wafer-level packaging super TSV copper interconnection material. The electroplating copper solution comprises,according to the concentration, 100-250 g / L of concentrated copper sulfate pentahydrate, 40-80 g / L of concentrated sulfuric acid, 30-50 mg / L of chloride ions, 1-5 mg / L of 3-sulfur-isothiourea propanesulfonic acid inner salt, 50-100 mg / L nonylphenol polyoxyethylene ether, 40-80 mg / L of phenazine dye and the balance DI pure water; the components are uniformly mixed to form the electroplating coppersolution; before electroplating, the wafer is subjected to vacuum treatment by a pretreatment solution; the pretreatment solution is DI pure water, and the wafer is vacuumized by using DI pure waterin vacuum equipment for 5-10 min after the wafer is mounted by an electroplating hanger; and after vacuumizing, electroplating is carried out in the electroplating copper solution. The super TSV growsin the bottom-up form, so that the problems of voids, cracks and the like of existing super TSV are solved, and the defects of unstable signal transmission, large resistance, excessive power loss andthe like due to voids can be effectively avoided.

The invention is directed to nucleic acid sequences which encode polypeptides having PhzO activity, namely, the ability to convert phenazine-1-carboxylic acid to a 2-hydroxylated phenazine, and isolated polypeptides having this activity. The invention is also directed to recombinant nucleic acid molecules, vectors, and host cells including the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in bacterial or plant cells to inhibit fungal pathogens.

The invention discloses a rhizospheric pseudomonad capable of largely producing phenazine-1-carboxylic acid and phenazine-1-amide. The rhizospheric pseudomonad is Pseudomonas aeruginosa PA1201CCTCC No: M2013441. The strain PA1201 is a wild type environmental microorganism separated and purified when a root system soil sample is collected in a rice field in the suburb of Chongqing. The strain disclosed by the invention can be used for stably and efficiently producing the bactericidal agent phenazine-1-carboxylic acid and the novel bactericidal compound phenazine-1-amide, effectively inhibits the growth of rice diseases: Rhizoctonia solani and Xanthomonasoryzae pv.oryzae and can be used for preparing a microbial source pesticide capable of effectively controlling the fungous diseases and bacterial diseases of plants by utilizing the fermentation secondary metabolite of the strain.

The invention belongs to the field of organic electroluminescent materials and particularly relates to a novel thermal-activated-delayed-fluorescence luminescent material and an application thereof. The material is characterized by comprising a structure represented by a formula (1) shown in the description, wherein R1 and R2 each is any one independently selected from a group consisting of a hydrogen atom, a C3-C30 substituted or unsubstituted carbazolyl group, a C3-C30 substituted or unsubstituted arylamine group, a C3-C30 substituted or unsubstituted phenothiazine group, a C3-C30 substituted or unsubstituted phenoxazine group, a C3-C30 substituted or unsubstituted phenazine group and a C3-C30 substituted or unsubstituted acridine group, and R1 and R2 are not hydrogen simultaneously; and R3 is any one selected from a group consisting of hydrogen and C1-C10aliphatic straight-chain or branched-chain alkane. The material provided by the invention is stable in property, has good luminescent performance and is applied to organic electroluminescent devices as a luminescent material.

The invention discloses an alkaline hydroxyl phenazine organic flow battery and a preparation method thereof; the preparation method comprises the steps of enabling hydroxyl phenazine substituted by different functional groups to be neutralized by alkali, and then to be dissolved in an alkali solution to serve as a negative electrode electrolyte; dissolving potassium ferrocyanide in alkali to serve as a positive electrode electrolyte; and loading the positive electrode electrolyte and the negative electrode electrolyte in a positive electrode electrolyte tank and a negative electrode electrolyte tank respectively, and carrying out assembling to form a battery. According to the method, the problem that the existing negative electrode is relatively high in attenuation rate is solved.

A method for inserting the gene of fluorescent pseudomonads M18 in the mutant strain M18G in order to develop efficient low-poison agricultural chemical includes designing facultative primer, PCR amplification of gacA fragment in M18 genon, using it as probe to screen positive clone from the plasmid library of M18 genom, using homogeneous recombination reject technique and solid-phase filter membrane triparent cross to obtain mutant strain M18G, and extracting and quantitatively testing phenazine-1-carboxylate.

The invention discloses a preparation method of a phenazine-connecting two-dimensional covalent organic framework material of a novel structure. The synthesized phenazine-connecting two-dimensional covalent organic framework material of the novel structure has a highly planar rigid structure in a graphene-like single layer, and is also highly conjugated between layers. A synthesis method is a solvothermal method and is easy and safe to operate, the reaction is a molecular level reaction, and the synthesized product is more ordered and more stable. According to the method, triphenylene-2,3,6,7,10,11-hexaaminotriphenylene and hexaketocyclohexane octahydrate serve as raw materials, 1,4-dioxane and 1,3,5-mesitylene serve as organic solvents, and the phenazine-connecting two-dimensional covalent organic framework material of the novel structure is successfully prepared through the solvothermal method under the condition that acetic acid is used for adjusting the acid environment.

The invention discloses a bactericidal composition and application thereof and relates to the technical field of pesticide combination. Effective ingredients of the bactericidal composition include prothioconazole A and antibiotic bactericide B, wherein the weight ratio of the prothioconazole A to the antibiotic bactericide B is 1:30-30:1. The antibiotic bactericide B can be kasugamycin, polyoxin, phenazine-1-carboxylic acid, streptomycin or validamycin. The prothioconazole A and the antibiotic bactericide B have obvious synergistic effects, the application amount of single dosage can be effectively reduced, good effect is played on enlargement on a bactericidal spectrum and delay on plant resistance to insecticide, a lasting period can be further prolonged, and the bactericidal composition has obvious promotional value. Assistant ingredients allowed in other pesticides can be added into the bactericidal composition to process any dosage form of insecticide. The bactericidal composition can effectively prevent and control rice sheath blight disease, rice blast, false smut, wheat rust, powdery mildew and the like.

The invention provides a method for synthesizing phenazine-1-carboxylic acid. The method comprises the following steps: dehydrating initial raw materials comprising catechol and 2,3-diaminotoluene in the nitrogen atmosphere, carrying out a cyclization reaction to generate 1-methy-5,10-dihydrophenazine, reacting with air for an oxidation reaction to obtain 1-methylphenazine, chlorinating 1-methylphenazine by chlorine under the catalysis of azodiisobutyronitrile, and hydrolyzing to obtain phenazine-1-carboxylic acid. The method solves the disadvantages of low efficiency, high cost, large wastewater amount and the like of previous production methods through biological fermentation, and is a new phenazine-1-carboxylic acid production technology having the advantages of high efficiency, low cost and environmental protection.