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169 results about "Naphthoquinone" patented technology

Naphthoquinone is a class of organic compounds structurally related to naphthalene.

Composite material and application thereof in electrochemical carbon dioxide capture

The invention discloses a composite material and application thereof in electrochemical carbon dioxide capture, and belongs to the technical field of electrochemistry and carbon dioxide capture. The composite material provided by the invention comprises a carbon felt and a 1, 4-naphthoquinone compound, the 1, 4-naphthoquinone compound is loaded on the carbon felt; the 1, 4-naphthoquinone compound comprises at least one of 1, 4-naphthoquinone, 2-methyl-1, 4-naphthoquinone or 2, 3-dimethyl-1, 4-naphthoquinone, and the compound is a compound of the 1, 4-naphthoquinone, the 2-methyl-1, 4-naphthoquinone and the 2, 3-dimethyl-1, 4-naphthoquinone. In the composite material disclosed by the invention, a 1, 4-naphthoquinone structure of the 1, 4-naphthoquinone compound can realize specific capture of CO2 through a reversible oxidation-reduction reaction, a carbon felt three-dimensional porous framework provides a smooth channel for CO2 mass transfer and electron transmission, and the 1, 4-naphthoquinone structure and the carbon felt three-dimensional porous framework cooperate with each other to solve the problems of low capture capacity, poor stability and high energy consumption of a traditional carbon material; therefore, the method has a good application prospect in electrochemical carbon dioxide capture.
Owner:CHONGQING UNIV +1

A composition for skin barrier repair and anti-inflammation after non-surgical cosmetic treatments and its application.

This invention belongs to the field of cosmetic technology, specifically relating to a composition for skin barrier repair and anti-inflammation after non-surgical cosmetic procedures and its application. The composition comprises Xinjiang comfrey peptide and Xinjiang comfrey naphthoquinone, with a mass ratio of 50-200:1. This composition synergistically inhibits the release of LPS-induced inflammatory factors, alleviating acute inflammatory reactions such as redness and burning after cosmetic procedures, achieving a dual effect of anti-inflammation and repair. The composition significantly reduces postoperative inflammatory redness and improves discomfort symptoms such as dryness and stinging. Through a multi-target mechanism, this invention solves the technical problems of existing repair products having single functions and slow onset of action, providing a highly efficient and comprehensive repair solution for skin after cosmetic procedures.
Owner:HANGZHOU ISLAND XINGQING BIOTECHNOLOGY CO LTD

A 2,3-disubstituted naphthoquinone compound and its uses and preparation method

This invention belongs to the field of veterinary drug technology, specifically relating to a 2,3-disubstituted naphthoquinone compound, its uses, and a preparation method. The 2,3-disubstituted naphthoquinone compound has the general formula: where X is selected from C, NH, O, and S; where X is selected from C, the X-R1 substituent represents an aryl substituent; when X is selected from NH, R1 is selected from hydrogen atom, C1-6 alkyl, C3-6 cycloalkyl, substituted aryl, substituted benzyl, or substituted acyl; when X is selected from O, R1 is selected from hydrogen atom, C1-6 alkyl, C3-6 cycloalkyl, C4-6 cycloalkyl, C5-6 cycloalkyl, C6-6 cyclo ... 3-6 cycloalkyl, substituted benzyl, substituted acyl; when X is selected from S, R1 is selected from C1-6 alkyl, substituted aryl, substituted benzyl; R2 is selected from C1-16 alkyl, substituted aryl, Ra-(CH2)n-, Ra-CO-(CH2)n-; This series of compounds has novel structures, excellent antiparasitic activity, and has been successfully applied in the field of veterinary drugs, solving long-standing safety and toxicity problems; its synthesis process is simple, the conditions are mild, and it can efficiently prepare a variety of 2,3-disubstituted naphthoquinone compounds.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS

Method for detecting content of trace metal ions in diazo naphthoquinone photosensitizer

The invention discloses a method for detecting the content of trace metal ions in a diazo naphthoquinone photosensitizer. The method comprises the following steps: sample pretreatment: weighing diazonaphthoquinone photosensitizer powder in a clean room, putting the diazonaphthoquinone photosensitizer powder into a cleaned and dried wide-mouth PFA bottle, adding an organic reagent, and carrying out ultrasonic treatment until a solid is completely dissolved; the method comprises the following steps: testing: adding a metal standard substance into an organic solvent to prepare three standard solutions with different concentrations; debugging an instrument, determining target metal in the standard solution in a Cool mode, a No Gas mode and a He mode by using an inductively coupled plasma mass spectrometer to obtain a signal intensity value (CPS value) corresponding to each metal ion concentration in the standard solution, and establishing a standard curve; and measuring the sample in which the photosensitizer is dissolved by using the same steps to obtain the content of metal ions in the sample. According to the method, appropriate detection conditions are optimized for different elements to be detected in the diazo naphthoquinone photosensitizer, polyatomic ion interference and matrix effect in a sample are mainly reduced, the content of 16 metal ions can be accurately detected at the same time, and the test efficiency is high.
Owner:HUBEI THREE GORGES LAB

A method for synthesizing pyridine-fused polycyclic nitrogen heteroaromatic compounds using electrochemical methods

The present invention belongs to the field of organic electrosynthesis and relates to a method for electrochemically synthesizing a pyridine-fused polycyclic nitrogen heteroaromatic compound. A 2-[2-phenylethynylamine]-1,4-naphthoquinone analogue, a quaternary ammonium salt and a Lewis acid are dissolved in an organic solvent to obtain a mixed solution; an electrode is inserted into the mixed solution, a constant current is connected in an inert gas atmosphere system, and an electric reaction is carried out with stirring to obtain a pyridine-fused polycyclic nitrogen heteroaromatic compound. The present invention adopts an electrochemical synthesis method, which significantly improves the reaction efficiency. The synthesis method of the present invention does not require an oxidant or a metal catalyst, is simple to operate, and is green and efficient. The pyridine-fused polycyclic nitrogen heteroaromatic compound prepared by the present invention has the characteristics of high biological activity and is widely applicable to the fields of medicine and functional materials. The pyridine-fused polycyclic nitrogen heteroaromatic compound prepared by the present invention can be used as a standard.
Owner:NANJING TECH UNIV

Naphthoquinone compound in radix arnebiae seu lithospermi as well as preparation method and application of naphthoquinone compound in preparation of medicine for treating cervical cancer

The invention relates to the technical field of separation and purification of radix arnebiae seu lithospermi, in particular to a naphthoquinone compound in radix arnebiae seu lithospermi, a preparation method of the naphthoquinone compound and application of the naphthoquinone compound in preparation of drugs for treating cervical carcinoma, the naphthoquinone compound in radix arnebiae seu lithospermi is chemically named as (Z)-2-ethoxy-5, 8-dihydroxy-3-(4-methyl-1, 3-pentadiene-1-yl) naphthalene-1, 4-diketone, and the structural formula of the naphthoquinone compound is shown in the description. The naphthoquinone compound in the lithospermum is disclosed for the first time, in-vitro anti-tumor pharmacodynamic experiments are carried out on the naphthoquinone compound in the lithospermum, and the experiments show that the naphthoquinone compound in the lithospermum has a certain inhibition effect on human Hela cells; therefore, the naphthoquinone compound in the radix arnebiae seu lithospermi can be applied to preparation of drugs for preventing / treating cervical cancer.
Owner:PEOPLES HOSPITAL OF XINJIANG UYGUR AUTONOMOUS REGION

Application of naphthoquinone compound in prevention and / or treatment of aquatic animal endoparasitosis

The invention provides application of naphthoquinone compounds in preparation of insecticides for preventing and / or treating parasitic diseases in aquatic animals, and belongs to the technical field of aquaculture. The naphthoquinone compound disclosed by the invention is 2-chloro-1, 4-naphthoquinone, and can be used for killing or preventing pyramidal bodies in aquatic animals. The invention also provides an insecticide for killing or preventing pyramidal worms in aquatic animals by using the naphthoquinone compound, and the insecticide comprises the following raw materials in percentage by weight: 20-30% of the naphthoquinone compound, 5-10% of a surfactant, 5-10% of a dissolving agent and the balance of water. An in-vitro insecticidal experiment and an in-vivo insecticidal experiment prove that the 2-chloro-1, 4-naphthoquinone can be used for efficiently killing insects; and the 2-chloro-1, 4-naphthoquinone has no obvious toxic or side effect on the fish body, and does not influence the growth and physiological functions of the fish body.
Owner:ZHEJIANG DANSHUI FISHERY RESEARCH INSTITUTE (ZHEJIANG DANSHUI FISHERY ENVIRONMENTAL MONITORING STATION) +1

A composition for treating atopic dermatitis and use thereof

The application belongs to the technical field of medicine or cosmetics, and particularly relates to a composition for treating atopic dermatitis and application thereof. The composition is composed of polysaccharide of Arnebia euchroma and naphthoquinone of Arnebia euchroma, and the mass ratio of the polysaccharide of Arnebia euchroma to the naphthoquinone of Arnebia euchroma is 250-500:1. The polysaccharide of Arnebia euchroma and the naphthoquinone of Arnebia euchroma are compounded according to a specific ratio, and the two components have a synergistic effect, can significantly inhibit secretion of inflammatory factors, and promote expression of key proteins of a skin barrier, so that atopic dermatitis is treated from two paths of 'anti-inflammation' and 'barrier repair', and the effect is significantly better than that of a single component. The composition of the application is derived from natural plant ingredients, has high safety, can be prepared into various dosage forms, is used for auxiliary treatment or daily care of atopic dermatitis, and has a good application prospect.
Owner:HANGZHOU ISLAND XINGQING BIOTECHNOLOGY CO LTD

Polyhydroxy phenolic compounds and methods for their preparation, diazonium naphthoquinone sulfonic acid esters and methods for their preparation, and photoresist compositions

The application provides a polyhydroxy phenolic compound, a preparation method thereof, a diazonium naphthoquinone sulfonate, a preparation method thereof and a photoresist composition. The polyhydroxy phenolic compound has the following structure shown in formula (I). The diazonium naphthoquinone sulfonate prepared by using the polyhydroxy phenolic compound provided by the application as an intermediate is applied to the photoresist composition as a photosensitive agent, and the obtained photoresist not only has clear resolution and high photosensitivity, but also has excellent thermal stability and etching resistance, and has a wide application prospect in the field of semiconductors.
Owner:CHANGZHOU TRONLY NEW ELECTRONICS MATERIALS CO LTD +2

Photoresist and preparation method thereof

The invention relates to the technical field of photoresists, and particularly provides a photoresist and a preparation method thereof.The photoresist is prepared from phenolic resin, a diazonaphthoquinone photosensitizer, phenyl triphenyl phosphate and a solvent, and the stability and definition of an exposed pattern are optimized through the combination of a special polymer, a sensitizer and the solvent. In the embodiment, the sensitivity range of the formula is 55 mJ / cm < 2 > to 120 mJ / cm < 2 >, the resolution ratio reaches 0.05 mu m, and burrs are controlled to be 0.05 mu m or below. The technology can be widely applied to the fields of semiconductor chip manufacturing, microelectronic packaging, display devices and nanotechnology, meets the production requirements of high precision and high efficiency, and has good market prospects and commercial application value.
Owner:WUHAN BRIGHT DIODE LASER TECH CO LTD

Naphthoquinone-based gas sensitive material, preparation method and application of naphthoquinone-based gas sensitive material in ammonia gas sensor

The invention discloses a naphthoquinone-based gas sensitive material, a preparation method and application of the naphthoquinone-based gas sensitive material in an ammonia gas sensor, and belongs to the technical field of gas sensors. The material is composed of divalent metal ions such as copper, nickel and cobalt and a polysubstituted naphthoquinone organic ligand, forms a one-dimensional chain structure, has a high specific surface area, an ordered electron channel and excellent molecular recognition capability, and can detect toxic gases such as ammonia gas at room temperature with high sensitivity. Macroscopic preparation of the material can be realized through solvothermal one-step reaction. Compared with the prior art, the one-dimensional coordination structure and ligand site engineering synergistically improve the carrier transport and molecular recognition capability, can realize continuous, real-time and selective detection of ammonia gas under complex working conditions, and has the advantages of high yield, large-scale preparation and excellent device application prospect.
Owner:AMERIASIA ACTIVATED CARBON PROD CO LTD

Application of naphthoquinone furan piperidone derivative in preparation of medicine for inhibiting bacteria

The invention discloses an application of a naphthoquinone furan piperidone derivative in preparation of a medicine for inhibiting bacteria. The naphthoquinone furan piperidone derivative disclosed by the invention has remarkable antibacterial activity on a plurality of gram-positive bacteria. The naphthoquinone furan piperidone derivative disclosed by the invention can be used for remarkably inhibiting the growth of MRSA (Methicillin-Resistant Staphylococcus Aureus) and shows relatively low drug resistance within 30 days. The naphthoquinone furan piperidone derivative can protect MRSA infected mice and improve the survival rate of the infected mice. The naphthoquinone furan piperidone derivative disclosed by the invention shows good safety and biocompatibility while keeping high antibacterial activity.
Owner:ZHEJIANG UNIV

Preparation method of low-odor arnebia euchroma (juss.) johnst. Extract and product and application thereof

PendingCN122075366AReduced volatile odorsmall smellCosmetic preparationsToilet preparationsBiotechnologyAlcohol
This invention belongs to the field of cosmetic raw material preparation technology, specifically relating to a method for preparing a low-odor Xinjiang Lithospermum extract, its product, and its application. The method includes: raw material pretreatment: drying and pulverizing Xinjiang Lithospermum raw material to obtain pretreated material; first-stage extraction: loading the pretreated material into a supercritical fluid extraction device, adding a composite entrainer for extraction, and collecting the first fraction in a first separator; second-stage extraction: collecting a second fraction rich in naphthoquinone components in a second separator; and post-treatment: concentrating the second fraction and removing the alcohol solvent to obtain the low-odor Xinjiang Lithospermum extract. This invention can separate and discard most of the odor-causing volatile components in the raw material under mild conditions in the first stage, and then efficiently extract the core active substances of naphthoquinone in the second stage, achieving a significant reduction in the odor of the extract and a significant improvement in its sensory quality.
Owner:HANGZHOU ISLAND XINGQING BIOTECHNOLOGY CO LTD

A process for the preparation of 2-hydroxy-1,4-naphthoquinone

The application provides a method for preparing 2-hydroxy-1,4-naphthoquinone, which comprises the following steps: S1: dispersing 2-naphthol, a phase transfer catalyst and a base in water to obtain a 2-naphthol alkali solution; S2: adding a hypochlorite aqueous solution to the 2-naphthol alkali solution at 5-30 DEG C, and then increasing the temperature to 50-60 DEG C to react, so that 2-naphthol is oxidized to an intermediate isomerization and rearrangement to generate 2-hydroxy-1,4-naphthoquinone salt, and a 2-hydroxy-1,4-naphthoquinone salt solution is obtained; S3: adjusting the pH of the 2-hydroxy-1,4-naphthoquinone salt solution, so that the 2-hydroxy-1,4-naphthoquinone salt is converted into 2-hydroxy-1,4-naphthoquinone and precipitated, and a 2-hydroxy-1,4-naphthoquinone crude product is obtained. The method uses 2-naphthol as a raw material, and high-purity and high-yield 2-hydroxy-1,4-naphthoquinone is obtained, while the safety hazards and environmental burdens caused by the use of a large amount of peroxide oxidants and metal catalysts are avoided, the process flow is simplified, and the method is more suitable for industrialization.
Owner:TIANMEN CHUTIAN JINGXI CHEM CO LTD

Anti-polymer compositions containing benzoquinone or naphthoquinone and oxygenated aminophenol and methods of use

Compositions and methods for inhibiting and retarding polymerization of monomeric compositions are described that use a naphthoquinone and an oxygenated aminophenol. When present in a monomer-containing composition, the combination of naphthoquinone and oxygen-containing aminophenol provides an unexpectedly beneficial anti-polymerization agent effect, thereby inhibiting the formation of unwanted fouling polymers. The anti-polymerization agent combination can be added to a hydrocarbon composition, such as petroleum, that can include a polymerizable component, such as styrene, wherein the hydrocarbon composition is purified or processed, such as under distillation.
Owner:ECOLAB USA INC

Sulfur-doped oxygen-nitrogen-enriched conjugated organic material and application thereof in Li < + > / Zn < 2 + > ion battery

PendingCN121537409AOrganic chemistryPositive electrodesElectrical batterySODIUM SULFIDE NONAHYDRATE
The invention belongs to the field of metal ion battery material synthesis, and particularly provides a sulfur-doped oxygen-nitrogen-enriched conjugated organic material and application thereof in Li < + > / Zn < 2 + > ion batteries. The preparation method comprises the following steps: firstly, preparing 2, 3, 8, 9, 14, 15-hexachlorodiquinoline [2, 3-a: 2 ', 3'-c] phenazine (HANT-Cl) by taking cyclohexanehexone and dichlorobenzene diamine as raw materials, and then synthesizing 6S6O and the derivative thereof by taking HATN-Cl, sodium sulfide nonahydrate and a naphthoquinone derivative as raw materials. The obtained electrode material contains a plurality of oxidation-reduction active sites, multi-electron storage can be carried out, the transfer rate of electrons is improved through the large pi conjugated structure of the conjugated quinoneazine material, and therefore the high theoretical specific capacity and the excellent rate performance are achieved. Due to the addition of the sulfur element, the oxidation-reduction potential of the material is improved, the energy density of a battery can be improved, and the material has a wide application prospect in a Li < + > / Zn < 2 + > ion battery system.
Owner:CHANGZHOU UNIV

Recombinant strain for improving efficient synthesis of vitamin k2 by saccharomyces cerevisiae and application thereof

PendingCN122344526AVitamin K2Heterologous
This invention belongs to the field of biotechnology and discloses a recombinant strain of Saccharomyces cerevisiae that enhances the efficient synthesis of vitamin K2 and its application. By heterologously integrating the hepS / T and naphthoquinone cyclotransferase genes (menA) of Bacillus subtilis, four genetically engineered strains were constructed based on the designed MK-7 biosynthetic pathway: YK-1, YK-2, YK-3, and YK-4. YK-1 is an expression strain containing the target genes MenF, MenD, and MenH; YK-2 is an expression strain integrating the target genes MenC, MenE, and MenB on the basis of YK-1; YK-3 is an expression strain integrating the target genes hepS and hepT on the basis of YK-2; and YK-4 is an expression strain integrating the target genes yuxO, MenA, and MenG on the basis of YK-3. YK-4 is the final engineered strain that produces high levels of vitamin K2. The optimal fermentation time was determined by measuring OD600 and yield curves. YK-4 reached its maximum cell concentration in 18 hours, which can effectively shorten the fermentation cycle.
Owner:DALIAN POLYTECHNIC UNIVERSITY

A hollow ZIF-8 immobilized dual enzyme and its preparation method and application

ActiveCN118879680BOxidoreductasesOn/in organic carrierNaphthoquinoneFormate dehydrogenase H
The present invention discloses a hollow ZIF-8 immobilized bienzyme and its preparation method and application, by embedding formate dehydrogenase and carbonic anhydrase in ZIF-67, then growing a layer of ZIF-8 shell on its surface, dissociating ZIF-67, and the formate dehydrogenase and carbonic anhydrase are fixed in the ZIF-8 shell in a free state, thereby maintaining a high enzyme activity to form a hollow ZIF-8 immobilized bienzyme. Utilizing 2-hydroxy-1,4-naphthoquinone coenzyme regeneration, bioelectrocatalytic CO2 reduction is achieved at the cathode. The preparation process of this method is simple to operate and easy to implement. The hollow structure is used to provide a soft microenvironment for the enzyme. Hollow ZIF-8 and carbonic anhydrase can increase the substrate CO2 adsorption capacity. Using 2-hydroxy-1,4-naphthoquinone regeneration can reduce the consumption of expensive coenzymes, and bioelectrocatalytic CO2 reduction has a higher formic acid yield.
Owner:HEBEI UNIV OF TECH

Non-planar pi-conjugated naphthoquinone derivative with asymmetric structure as well as preparation method and application thereof in aqueous flow battery

The invention discloses a non-planar pi-conjugated naphthoquinone derivative with an asymmetric structure, a preparation method of the non-planar pi-conjugated naphthoquinone derivative and application of the non-planar pi-conjugated naphthoquinone derivative in an aqueous flow battery, and relates to the technical field of electrochemical energy storage. Methyl 4-aminobenzoate is added into hydrochloric acid, then the mixture and sodium nitrite are dissolved in water to be mixed to obtain a diazonium salt solution, and 2-hydroxy-1, 2, 4-triazole is added into the diazonium salt solution to be mixed to obtain a diazonium salt solution; 2, 4-naphthoquinone is dissolved in a KOH solution and mixed with a diazonium salt solution, after hydrochloric acid acidification, acetic acid recrystallization purification is conducted, and BANQ is obtained; the capacity fading rate of the modified naphthoquinone derivative BANQ is as low as 0.00018% per circle, the modified naphthoquinone derivative BANQ shows excellent cycling stability and redox reversibility, the BANQ molecule has an asymmetric non-planar pi conjugation characteristic, and the sensitivity of a redox core to nucleophilic / electrophilic attack is greatly reduced, so that the cycling stability is improved, and the service life is prolonged. And a new direction and possibility are provided for constructing green sustainable large-scale organic redox active molecules for energy storage through artificial modification of natural products.
Owner:NANJING UNIV TIANCHANG NEW MATERIALS & ENERGY TECH R&D CENT +3

A method for preparing a monomethyl amine solution

ActiveCN117819571BCyanamideNaphthoquinoneHydroquinone
The application discloses a preparation method of monocyamine solution and belongs to the technical field of fine chemical industry. By optimizing the process conditions, especially adding new stabilizers of o-benzoquinone, 1,4-naphthoquinone and methylhydroquinone, the content of dicyandiamide in the monocyamine solution is reduced, and high-quality monocyamine with a concentration of 30% is produced at a lower temperature. The fine control technology of monocyamine low-temperature hydrolysis reaction developed by the application changes the prior art method, i.e. first hydrolyzing lime nitrogen in a hydrolysis kettle to produce monocyamine aqueous solution with a concentration of 18%, then concentrating through an evaporation system, and finally producing monocyamine finished product with a concentration of 30%. The application improves the product quality and reduces the product energy consumption through the "low-temperature one-step hydrolysis method" monocyamine production process without evaporation and concentration, so that the stable and green low-carbon production of high-grade monocyamine products is realized.
Owner:PINGLUO XIANG MEI CHEM CO LTD

A naphthoquinone compound with anti-tobacco black shank disease activity and a preparation method and application thereof

The application belongs to the technical field of agricultural chemistry, and particularly relates to a naphthoquinone compound with anti-tobacco black shank disease activity and a preparation method and application thereof. The naphthoquinone compound is extracted from honeysuckle branches with high-concentration methanol, high-concentration acetone / water or high-concentration ethanol / water, the extract is combined, filtered, and concentrated into an extract under reduced pressure; the extract is subjected to silica gel column chromatography by dry column packing with silica gel; gradient elution is performed with chloroform-acetone solution; and the 7:3 part of the eluate is further separated and purified by high-performance liquid chromatography to obtain the required naphthoquinone compound. The application also discloses the application of the compound. The active test shows that the compound has a good inhibitory effect on tobacco black shank disease. The compound has a novel structure, good anti-black shank disease activity, and can be used as a lead compound for anti-tobacco black shank disease and for the research and development of anti-tobacco black shank disease biological pesticides.
Owner:YUNNAN MINZU UNIV

Method for improving synthesis yield of vitamin K3

The invention discloses a method for improving the synthesis yield of vitamin K3, which comprises the following steps: S1, adding beta-menadione and sodium pyrosulfite into a container, adding ethanol as a solvent, stirring to react for 1-2 hours at the reaction temperature of 30-50 DEG C, heating to 40-70 DEG C, keeping the temperature for 10-60 minutes, and filtering while hot after the reaction is completed to obtain filtrate; and S2, adding sodium pyrosulfite into the filtrate, and then freezing, crystallizing, filtering, washing and drying to obtain a vitamin K3 finished product. When the vitamin K3 is prepared through cooling crystallization, the sodium pyrosulfite is added into the filtrate to be crystallized, so that the crystallization yield of the vitamin K3 can be effectively improved.
Owner:YUNNAN LULIANG PEACE TECH CO LTD

A trifluoromethylseleno naphthoquinone derivative, preparation and application thereof

PendingCN122255045AMild conditionsExcellent VDR agonistic activityOrganic chemistryAntipyreticChemical synthesisPhenyl group
This invention discloses a trifluoromethylselenoquinone derivative, its preparation, and its application. The structure of the trifluoromethylselenoquinone derivative is shown in formula (I). Wherein, the R1 group is selected from H, halogens, C... 1‑5 Alkyl, C 1‑5 One of alkoxy and acetyl groups, and R2 group selected from monosubstituted or unsubstituted phenyl and thiophene groups. This invention is the first to develop a photochemical synthesis method for trifluoromethylselenoquinone derivatives. This method uses visible light as a clean driving force and has the advantages of mild conditions and environmental friendliness. This invention successfully introduces the trifluoromethylseleno group into the naphthoquinone core, constructing a novel functional molecule that integrates the advantages of the naphthoquinone skeleton, fluorine atom, and chalcogenide triple structure, enriching the library of fluorine-containing chalcogenide heterocyclic compounds and providing a novel structural unit for innovative drug development. The compound synthesized in this invention exhibits excellent VDR agonist activity and has good drug development prospects. (I)
Owner:NANTONG UNIV

Direct air capture system

An electrode for an electrochemical cell, comprising a composite material comprising graphite coated with one or more quinone species capable of bonding with carbon dioxide when the quinone species is in a reduced state and releasing bound CO2 when the quinone species is in an oxidised state. The graphite may have a particle diameter of less than 1 mm, less than 500 µm, less than 400 µm or less than 300 µm. The quinone species may be selected from benzoquinone, 1,4-naphthoquinone, 1,2-naphthoquinone, anthraquinone, phenanthrenequinone, benzanthraquinone, dibenzanthraquinone or 4,5,9,10-pyrenetetrone, or homopolymers, copolymers, homooligomers or cooligomers comprising these. The electrode may comprise a support material on which the composite material is dispersed. An electrochemical cell comprising the electrode, optionally further comprising a second electrode, a separator between the electrodes, and an electrolyte, optionally an ionic liquid. A gas separation system comprising the electrochemical cell. A gas separation system comprising the electrochemical cell in fluid communication with gas inlet(s) and outlet(s).
Owner:CARBONBIT TECHNOLOGIES LTD

Novel 1,4-naphthoquinone derivative and method for preparing same

The present invention relates to a novel 1,4-naphthoquinone derivative, a preparation method therefor, and uses thereof, and the derivative acting as a substrate for NQO1 and effectively increasing enzyme activity has been been confirmed. Therefore, a compound according to the present invention can prevent, alleviate, and / or treat various diseases associated with a decrease in NAD+ or mitochondrial dysfunction by increasing NQO1 activity and consequently increasing in NAD+.
Owner:CUROME BIOSCIENCES CO LTD

Rationally designed lawsone derivatives as antimicrobials against multidrug-resistant Staphylococcus aureus

Naphthoquinone derivatives of Lawsone have been found to be effective against Staphylococcus aureus and methicillin resistant Staphylococcus aureus (MRSA). Such compounds generally contain a substituent group at the 3-position of a specific naphthoquinone compound, i.e. 2-hydroxy-1,4-naphthoquinone. One of these derivatives referred to as compound 6c in the series exhibits potent antimicrobial activity that is comparable to that of the two commercial antibiotics ofloxacin and ciprofloxacin against the two strains of methicillin sensitive Staphylococcus aureus (MSSA; ATCC 29213 and ATCC 6538). In the case of two strains of MRSA (ATCC BAA-44 and ATCC BAA-1717) that have developed drug resistance to both ofloxacin and ciprofloxacin, the antimicrobial activity of 6c can almost rival that of vancomycin and daptomycin. Furthermore, 6c is also effective against vancomycin-intermediate and daptomycin non-susceptible strain of MRSA (ATCC 700699). Besides the efficacy, 6c has a much improved drug resistance profile in comparison with the conventional antibiotics.
Owner:KENT STATE UNIV

Carbon nano chemical indicator, preparation method thereof and application of carbon nano chemical indicator in bacterial proliferation monitoring

The invention discloses a carbon nano chemical indicator, a preparation method thereof and application of the carbon nano chemical indicator in bacterial proliferation monitoring. The method comprises the following steps: S1, preparing nitrogen-sulfur co-doped carbon quantum dots; and S2, carrying out surface modification by adopting 1, 2-naphthoquinone-4-sodium sulfonate, so as to obtain the carbon nano chemical indicator. The intelligent response type chemical indicator based on the carbon quantum dots is innovatively developed, according to the scheme, a specific response system is constructed through surface modification of the carbon quantum dots, and real-time and in-situ visual monitoring of bacterial proliferation is achieved through fluorescence / color dual-mode changes triggered by a bacterial metabolism microenvironment; compared with a traditional method, the method has the outstanding advantages that the response is fast (lt; the method can realize dynamic monitoring, does not need complex pretreatment, supports nondestructive detection, reduces the detection cost by more than 80%, has double functions of naked eye visualization and instrument quantitative detection, and is suitable for universal detection of a plurality of common bacteria.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI

Electrochemical adsorption material and device for capturing carbon dioxide

The invention relates to an electrochemical adsorption material and device for capturing carbon dioxide, the adsorption material is composed of an integrated cathode adsorption material, an integrated anode charge balance material and a gel electrolyte, the integrated cathode adsorption material is a polynaphthoquinone-carbon cloth composite material, and the integrated anode charge balance material is a polynaphthoquinone-carbon cloth composite material. The integrated anode charge balance material is a ferrocene-carbon cloth composite material, and the gel electrolyte is a polyion liquid-silicon dioxide gel electrolyte. The method has the advantages that the electrochemical adsorption material has the advantages of high activity (good adsorption performance), high stability (the performance is not reduced after long-term use) and the like, a matched device is modularized, easy to maintain and compact in size, auxiliary equipment is not needed, the capacity is not influenced by the feeding concentration, the purity of released CO2 can be close to 100%, efficient trapping of a wide-concentration CO2 gas source (0.6%-10%) is achieved, and the method is suitable for industrial production. Capturing efficiency and energy consumption control are both considered, and multi-scene application requirements are met.
Owner:致和半导体设备(江苏)有限公司

Extraction method and identification method of 2-methoxy-1, 4-naphthoquinone compound in impatiens balsamina

The invention belongs to the technical field of extraction of plant extracts, and particularly relates to an extraction method and an identification method of a 2-methoxy-1, 4-naphthoquinone compound in impatiens balsamina. The method comprises the following steps: soaking the overground part of impatiens balsamina with ethyl acetate, and then carrying out ultrasonic disruption, flash extraction, standing and solid-liquid separation to obtain a crude extract; the crude extract is sequentially subjected to first silica gel column chromatography, second silica gel column chromatography and recrystallization, and the 2-methoxy-1, 4-naphthoquinone compound is obtained. According to the extraction method provided by the invention, the high-purity 2-methoxy-1, 4-naphthoquinone compound can be obtained, meanwhile, the extraction method is simple, convenient, stable and reliable, and is suitable for large-scale production, and conditions are created for development and utilization of the 2-methoxy-1, 4-naphthoquinone compound.
Owner:SHANXI AGRI UNIV