709 results about "Naphthoquinone" patented technology

Methods of treating, preventing or suppressing symptoms associated with mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), dominant optic atrophy (DOA); mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Leigh syndrome or Kearns-Sayre Syndrome (KSS) with compounds of Formula (I) are disclosed. Methods of modulating, normalizing, or enhancing energy biomarkers, as well as compounds useful for such methods are also disclosed.

The present invention relates to methods and compositions comprising naphthoquinones such as 2,3-dimethylnaphthalene-1,4-dione, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.

A positive resist mainly composed of a novolak resin and comprising a naphthoquinone diazido-based photosensitizer as an energy beam sensitive resin (e.g., a photosensitive resin) is applied in a thickness of 0.1 to 0.2 mum to a surface of a glass substrate 1 provided with transparent electrodes and dried so as to form a photosensitive film. Next, using a mask, the film is exposed to ultraviolet rays (365 nm). Then, moisture in the air reacts with the resist in an exposed portion 2', thereby generating -COOH groups, with which CH3(CH2)18SiCl3 is allowed to react so as to cause a dehydrochlorination reaction, thereby forming a monomolecular chemisorption film 6 comprising carbon chains 8. This film is used as an alignment film. Thus, the present invention provides a method for producing a uniform and thin alignment film for use in a liquid crystal display panel with a high efficiency without performing a rubbing treatment, and a method for producing a display panel using the same.

Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging, or for modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, wherein the compounds are quinone or naphthoquinone compounds with carboxylic acid or carboxylic acid derivative substituents.

Provided is a use of a prodrug composition containing a naphthoquinone-based compound of Formula 1 for the manufacture of a medicament for treatment or prevention of metabolic syndrome diseases.

An oxygen scavenger, containing a heterocyclic compound having a N-substituted amino group as an effective component, can adequately exhibit the oxygen scavenging effect in not only feed water lines for high temperature water, a boiler, and steam and condensate return lines, but also feed water lines for low temperature water. The oxygen scavenger contains: a heterocyclic compound having a N-substituted amino group or a salt thereof; a hydroxybenzene derivative and/or a naphthoquinone derivative; and neutral amine.

A non-toxic biologically active compound is provided having the following general formula (I):

wherein n is an integer from 1 to 14, preferably from 2 to 4, and R is an organic moiety, preferably a group different from but structurally substantially similar to 2-methyl naphthoquinone, or a group P—C(R₁)—P, where each P stands for a—PO(OH)₂ group and R₁ is a (poly)isoprenyl group, hydroxy, halogen (preferably chloro or bromo), or hydrogen, or a pharmaceutically acceptable derivative thereof. These compounds are useful for the treatment or prevention of certain disorders in a mammal, especially a human being, for example postmenopausal loss of bone in women, juvenile or senile osteoporosis in men and women, cardiovascular calcification and other ectopic calcifications.

The present invention relates to a positive type photosensitive resin precursor composition which is characterized in that it contains polymer having, as its chief component, structural units represented by the following general formula (1) and, furthermore, in that it satisfies the following conditions (a) and/or (b). The invention provides an alkali-developable photosensitive composition.(a) There is included an ester of a naphthoquinone diazide sulphonic acid and a phenol compound of dipole moment 0.1 to 1.6 debye(b) There is included a phenol compound represented by general formula (8) and a naphthoquinone diazide sulphonic acid and/or an ester of a phenol compound represented by general formula (8) and a naphthoquinone diazide sulphonic acid(In general formula (1), R1 represents a bivalent to octavalent organic group with at least two carbon atoms, R2 represents a bivalent to hexavalent organic group with at least two carbon atoms, and R3 represents hydrogen or an organic group with from one to ten carbons. n is an integer in the range 10 to 100,000, m is an integer in the range 0 to 2, and p and q are integers in the range 0 to 4, but p and q are not simultaneously 0.)(In the formula, R23, R24, R26 and R27 each represents a hydrogen atom or a C1-8 alkyl group, alkoxy group, carboxyl group or ester group. At least one R25 is hydroxyl group, while the rest represent hydrogen atoms and C1-8 alkyl groups. aa, bb, cc and dd represent integers in the range 0 to 3. However, aa+bb<=5, bb+dd<=5 and aa+bb>0. ee represents an integer in the range 1 to 3.)

In a patterning process of a semiconductor device having inverted stagger type TFTs, a normal photolithography step using diazo naphthoquinone (DNQ)-Novolac resin based positive photo resist is applied, and a problem of the area dependency of the photo resist pattern side wall taper angle may occur. The problem is critical for the reason of influence on variation of an etching shape in a dry-etching step. The present invention has an object to solve the above problem. In a photolithography step, which is patterning step of a semiconductor device having inverted stagger type TFTs, by adjusting a pre-bake temperature or a PEB (post-exposure-bake) temperature, and positively performing evacuation of solvent in a state of a photo resist film, the volume contraction by evacuation of solvent at the post-bake is reduced, and the problem of the area dependency of the photo resist pattern side wall taper angle is solved, which is deformation due to the volume contraction.

A positive photosensitive siloxane composition comprising at least three types of following polysiloxanes (A), (B) and (C) obtained by hydrolyzing and condensing a silane compound represented by general formula (1) R¹_nSi (OR²)_4-n, a diazonaphthoquinone derivative, and a solvent: a polysiloxane (A) such that if pre-baked the film thereof will be soluble in a 5 weight % TMAH aqueous solution and the solution rate of said film will be 1,000 Å/sec or less; a polysiloxane (B) such that if pre-baked the solution rate of the film thereof will be 4,000 Å/sec or more relative to a 2.38 weight % TMAH aqueous solution; and a polysiloxane (C) such that if pre-baked the solution rate of the film thereof will be between 200 and 3,000 Å/sec relative to a 2.38 weight % TMAH aqueous solution. (In the formula, R¹ represents a C1-20 linear or branched cyclic alkyl group, in which any methylene may be substituted by oxygen, or a C6-20 aryl group, in which any hydrogen may be substituted by fluorine; n represents a 0 or a 1; and R² represents a C1-5 alkyl group.)

The invention provides an ultraviolet positive photoresist suitable for exposure under a UV light source. The photoresist is composed of, by mass percent, 1 to 10% of diazonaphthoquinone sulfonate photosensitizer with special structure, 10 to 50% of linear phenolic resin, 0.2 to 1% of sensitizer, 0.1 to 1% of toughening agent, 0.4 to 1% of adhesion promoter, 0.2 to 1% of leveling agent and the balance of solvent; wherein the diazonaphthoquinone sulfonate photosensitizer with special structure is obtained by subjecting 1, 1- P-hydroxyphenyl-[1-Biphenyl group-4-Isopropyl group-(1-o-methyl-4-phenol)] propane and 2-Diazo-1-Naphthoquinone-5-sulfonyl chloride to substitution reaction or esterification reaction according to the ratio of 1: 2; The linear phenol-formaldehyde resin is a mixture oflinear phenol-formaldehyde resin 1 and linear phenol-formaldehyde resin 2, and the weight ratio of linear phenol-formaldehyde resin 1 and linear phenol-formaldehyde resin 2 is 2-8: 8-2. The ultraviolet positive photoresist of the present invention has higher resolution, photosensitivity and size reducibility than the conventional diazonaphthoquinone sulfonate Phenolic resin system photoresist.

Provided are a photosensitive silane coupling agent for forming a low-defect microparticle pattern, dot array pattern, or hole array pattern through fewer steps, and a method of forming a pattern using such photosensitive silane coupling agent. Used is a photosensitive silane coupling agent comprising a 1,2-naphthoquinone-2-diazido-5-sulfonyl group or a 1,2-naphthoquinone-2-diazido-4-sulfonyl. group.

The invention discloses a preparation method of a polypyrrole functional mediator doped with a water-soluble anthraquinone or naphthoquinone compound and application thereof. Specifically, the preparation method comprises: (1) preparing a polymerization solution: firstly preparing a saturated solution of the water-soluble anthraquinone or naphthoquinone compound, then adding 0.33-0.67mL of pyrrole to every 100mL of the saturated solution and mixing well; (2) pretreating active carbon felt and platinum plate electrodes; (3) embedding the pretreated platinum plate electrodes in step (2) into the active carbon felt, then conducting electrochemical polymerization in the polymerization solution, with a polymerization potential of 0.30-0.50V, a polymerization time of 1-3h and a potential changerate of 0.03-0.07V/s. The polypyrrole functional mediator provided in the invention plays an accelerating role in a microorganism denitrification process, and is recyclable and free of secondary pollution.

The present invention belongs to the preparation process of water base developing photosensitive polyimide material. Aromatic dialphanyl diacyl chloride, 3,5-diamino benzoic acid, 4, 4'-diamino-3, 3'-dihydroxy diphenyl methane and 4, 4'-diamino-3, 3'-dihydroxy diphenyl sulfone are polymerized to produce polyamate as one kind of imide prepolymer. The prepolymer has characteristic viscosity of 0.35-0.50, and when 2-diazo naphthoquinone derivative as photosensitizer is added, the prepolymer becomes excellent photosensitive material with high photosensitive performance, good filming performance and high heat resistance.

An immobilization carrier containing an electron acceptor compound is used in addition to glutaraldehyde and poly-L-lysine to immobilize an enzyme and an electron acceptor compound simultaneously to an electrode. For example, here are used diaphorase as the enzyme and 2-amino-3-carboxy-1,4-naphthoquinone (ACNQ) as the electron acceptor compound.

The invention relates to a cyanide-free silver plating solution additive which comprises the following components by ratio: 0.1-10g/ l of brightener, 5-10g/ l of leveling agent, 100-600g/ l of complexing agent and the balance of plasma water, wherein the brightener is one or mixture of more in nitrogen-containing compound, triazole, benzotriazole, 2-hydroxypyridine, pyridine, 22 dipyridyl, 1, 10-phenanthroline, triethylene tetramine and diethylene triamine according to any ratio; the leveling agent is one or mixture of more in aromatic hydrocarbon compounds, naphthalene, 1-methylnaphthalene, 1, 4-naphthoquinone and 1-naphthol according to any ratio; the complexing agent is one or mixture of more in disodium ethylenediamine tetraacetate, niacin, aminosulfonic acid and potassium pyrophosphate according to any ratio. The cyanide-free silver plating solution additive has the beneficial effects that the plating solution is stable, low in toxicity and good in dispersing ability; the obtained plating layer is bright and fine as well as good in binding force; the technology adopts the environment-friendly organic additive which does not contain heavy metal and sulfide; the plating layer is good in corrosion resistance. Furthermore, the cyanide-free silver plating solution additive can be directly used for parts such as brass, copper, chemical nickel and the like, preplating is not needed, and the binding force is also guaranteed.

The invention relates to a preparation method of 2,2'-bis(trifluoromethyl)-4,4'-diaminodiphenyl. The preparation method comprises the following steps: synthesizing 3,3'-bis(trifluoromethyl)hydrazo-benzene in an inorganic alkaline aqueous solution by adopting nitrobenzotrifluoride as a raw material, adopting a phase transfer catalyst, a co-catalyst and Pd/C as a catalytic system and adopting aromatic hydrocarbon as a solvent, and performing the re-arrangement reaction on the 3,3'-bis(trifluoromethyl)hydrazo-benzene in an inorganic acid aqueous solution, thus obtaining 2,2'-bis(trifluoromethyl)-4,4'-diaminodiphenyl, wherein the phase transfer catalyst is one or a mixture of more of sodium dodecyl benzene sulfonate, sodium dodecyl sulfate and cetyl trimethyl ammonium bromide, and the co-catalyst is one or a mixture of more of 2,3-dichloro-1,4-naphthoquinone, 2-hydroxyanthraquinone and 2,6-dioxyanthraquinone. The preparation method has the advantages of mild reaction condition, simple process, high product quality and yield, low production cost, environmental friendliness, suitability for continuous production and the like.

The invention discloses an electroplating solution for copper plating and a preparation method thereof. The method comprises the steps that (1) copper salt, a quinonyl compound, catechol, potassium sulfate, malic acid, 2,2'-dipyridyl, complexing agents, reducing agents, stabilizer and water are mixed, and a mixture M1 is obtained; (2) alkaline is added to the mixture M1, the pH value is adjusted to 11-13, and a mixture M2 is obtained; and (3) the mixture M2 is post-processed, and the electroplating solution for copper plating is obtained. The quinonyl compound is one or several of 1,2-naphthoquinone, 1,4-naphthoquinone and anthraquinone. The electroplating solution for copper plating prepared through the method is stable in performance, and a copper-plated layer obtained through electroplating with the electroplating solution for copper plating is high in adhesive force, large in hardness and not prone to expanding and blistering.

The invention discloses a battery negative electrode active material based on a quinone structure, and a preparation method and an application of the battery negative electrode active material. The battery negative electrode active material comprises a quinone compound taking the quinone structure as an electrochemical oxidation-reduction reaction site, wherein the quinone compound comprises any one of a benzoquinone sodium salt derivate, an anthraquinone sodium salt derivate, or a naphthoquinone sodium salt derivate. The benzoquinone sodium salt derivate, the anthraquinone sodium salt derivate, or the naphthoquinone sodium salt derivate comprises at least one of the following groups of -ONa, -SO3Na, or -COONa.

In accordance with the present invention, a novel aromatic prenyltransferase, Orf2 from Streptomyces sp. strain CL190, involved in naphterpin biosynthesis has been identified and the structure thereof elucidated. This prenyltransferase catalyzes the formation of a C—C bond between a prenyl group and a compound containing an aromatic nucleus, and also displays C—O bond formation activity. Numerous crystallographic structures of the prenyltransferase have been solved and refined, e.g., (1) prenyltransferase complexed with a buffer molecule (TAPS), (2) prenyltransferase as a binary complex with geranyl diphosphate (GPP) and Mg²⁺, and prenyltransferase as ternary complexes with a non-hydrolyzable substrate analogue, geranyl S-thiolodiphosphate (GSPP) and either (3) 1,6-dihydroxynaphthalene (1,6-DHN), or (4) flaviolin (i.e., 2,5,7-trihydroxy-1,4-naphthoquinone, which is the oxidized product of 1,3,6,8-tetrahydroxynaphthalene (THN)). These structures have been solved and refined to 1.5 Å, 2.25 Å, 1.95 Å and 2.02 Å, respectively. This first structure of an aromatic prenyltransferase displays an unexpected and non-canonical (β/α)-barrel architecture. The complexes with both aromatic substrates and prenyl containing substrates and analogs delineate the active site and are consistent with a proposed electrophilic mechanism of prenyl group transfer. These structures also provide a mechanistic basis for understanding prenyl chain length determination and aromatic co-substrate recognition in this structurally unique family of aromatic prenyltransferases. This structural information is useful for predicting the aromatic prenyltransferase activity of proteins.

The invention provides a photochromic fiber as well as a preparation method and an application thereof. The photochromic fiber is a double-component composite fiber with a skin-core structure, wherein in a cross section of the double-component composite fiber with the skin-core structure, a skin layer and a core layer are in a concentric structure; the skin layer of the double-component composite fiber with the skin-core structure is made of low-smelting-point polyethylene terephthalate added with a phenoxy naphtho-naphthoquinone additive; the core layer is made of fiber-grade polyethylene terephthalate. The invention further provides the preparation method of the photochromic fiber. The photochromic fiber has good photochromism, heat stability, fatigue durability, short responding time, simple process and long service life, can serve as an anti-counterfeiting identification element for safe anti-counterfeiting and can also be used for garment materials and advertisements to increase the aesthetic feeling.

The invention discloses a preparation method of a chiral spiro naphthoquinone benzopyran hydroxyindole compound. The method comprises the following specific steps: reacting the condensation product of an isatin compound and propane dinitrile and a 2-hydroxyl-1,4-naphthoquinone compound in a solvent under the catalysis of quinine thiourea dihydride, thereby obtaining a product. According to the method, raw materials are simple and easily available, the reaction condition is mild, the post-treatment is simple and convenient, the applicative substrates are wide, the enantioselectivity is high, and the yield can reach 99%; therefore, the method is a novel method capable of efficiently synthesizing the chiral spiro naphthoquinone benzopyran hydroxyindole compound having important medicinal value and asymmetric synthesis value. The compound prepared by the method can be used for preparing intermediates of chiral drugs and has wide physiological and pharmacological activities.

The invention relates to a method for treating naphthoquinone production liquid waste containing hexavalent chromium and vitamin K3 production wastewater and co-producing chromium oxide green. The method comprises the following steps: a) carrying out liquid phase reaction between the naphthoquinone production liquid waste and the vitamin K3 production wastewater at 80-260 DEG C, wherein the naphthoquinone production liquid waste is excessively used relative to a necessary dosage of complete reduction; b) adding a reducing agent into the obtained reaction mixture to reduce the residual hexavalent chromium; c) regulating the pH of the obtained reaction mixture to 5.5-8.5 to separate out chromium hydroxide, and separating to obtain the chromium hydroxide and filtrate; and d) transforming the chromium hydroxide obtained in the step c) into chromium oxide green. The method can be used for effectively treating the naphthoquinone production liquid waste and the vitamin K3 production wastewater generated in a vitamin K3 production chain and recycling effective components in the liquid waste to turn waste into wealth and improve the economic and environmental protection benefits at the same time.

This invention discloses a method for synthesizing vitamin K2 product. The method comprises: reducing 2-methyl-1, 4-naphthoquinone into hydroquinone by using KBH4, performing Fridel-Crafts alkylation reaction with long-chain tert-terpenol in nitromethane/n-hexane system with anhydrous ZnCl2, boron trifluoride diethyl etherate and CuBr as the catalysts to introduce long-chain terpenyl to the C3 site of hydroquinone, oxidizing with isopropanol solution of FeCl3 to obtain corresponding vitamin K2. The method has such advantages as mild reaction conditions, high yield, recoverable reagents, and no environmental pollution.