78 results about "Quinone Compound" patented technology

The invention provides application of naphthoquinone compounds in preparation of insecticides for preventing and / or treating parasitic diseases in aquatic animals, and belongs to the technical field of aquaculture. The naphthoquinone compound disclosed by the invention is 2-chloro-1, 4-naphthoquinone, and can be used for killing or preventing pyramidal bodies in aquatic animals. The invention also provides an insecticide for killing or preventing pyramidal worms in aquatic animals by using the naphthoquinone compound, and the insecticide comprises the following raw materials in percentage by weight: 20-30% of the naphthoquinone compound, 5-10% of a surfactant, 5-10% of a dissolving agent and the balance of water. An in-vitro insecticidal experiment and an in-vivo insecticidal experiment prove that the 2-chloro-1, 4-naphthoquinone can be used for efficiently killing insects; and the 2-chloro-1, 4-naphthoquinone has no obvious toxic or side effect on the fish body, and does not influence the growth and physiological functions of the fish body.

The present invention aims to provide a vehicle composition for inorganic fine particle dispersion which has excellent decomposability at low temperature and enables degreasing in a short time, an inorganic fine particle-dispersed slurry composition containing the vehicle composition for inorganic fine particle dispersion, and a method for producing an inorganic fine particle-dispersed sheet with the inorganic fine particle-dispersed slurry composition. The present invention relates to a vehicle composition for inorganic fine particle dispersion, containing a binder resin, an organic solvent, and an organic compound having a boiling point at normal pressure of 200° C. or higher and lower than 400° C., the binder resin containing a (meth)acrylic resin, the organic compound containing at least one selected from a phenol compound, an aromatic amine compound, a quinone compound, and a nitro compound, the amount of the organic compound being 1 to 100 parts by weight relative to 100 parts by weight of the binder resin.

The invention relates to application of anthraquinone compounds and pharmaceutically acceptable salts thereof in preparation of drugs for treating anemia, the anthraquinone compounds have a structure as shown in formula I. In the formula I, R1-R5 are independently selected from hydrogen, hydroxyl, unsubstituted or hydroxyl-substituted C1-C6 linear or branched alkyl, C1-C6 alkoxy, C1-C6 acyl or-(CH2) n1O (CH2) n2CH3, n1 is selected from 1, 2 or 3, and n2 is selected from 0, 1, 2 or 3. The anthraquinone compound provided by the invention can significantly up-regulate the transcriptional levels of HAMP, EPO and HBG1 genes, has a good treatment effect on thalassemia and beta-sickle anemia, has no significant influence on cell viability and mouse weight, and has medication safety.

The invention relates to the use of a compound of Formula (I) as described herein and its effective dose in the prevention and / or treatment of fibrosis diseases. The compound can effectively prevent and / or treat a fibrosis disease without cytotoxicity or genotoxicity.

The invention is applicable to the technical field of colorimetric detection, and provides a bisphenol A colorimetric detection method based on copper-based nano enzyme. The copper-based nano-enzyme with laccase-like activity is prepared in an alkaline water phase system through a one-step method by taking low-price natural plant protein-zein as a ligand, divalent soluble copper salt as a metal precursor and hydroxylamine and the like as a reducing agent. The copper-based nano enzyme is superior to natural laccase in the aspects of catalytic activity, substrate affinity and stability, and bisphenol A can be catalyzed to be oxidized to generate quinone compounds; the quinone compound is further subjected to a coupling reaction with 4-aminoantipyrine, and a red product with a remarkable characteristic absorption peak at the wavelength of 510 nm is generated. The quantitative analysis of bisphenol A can be realized by measuring the absorbance of the system at 510nm. The method has the advantages of high sensitivity, low detection cost, simplicity and convenience in operation and the like, and is suitable for rapid detection of bisphenol A in drinking water and environmental water.

This invention discloses a method for iron-catalyzed methylation of quinone compounds, comprising the following steps: in a solvent, using 2-aryl-2-propanols as methylating agents, peroxides as oxidants, iron as catalysts, and amino acids or their derivatives as ligands, oxidizing the C(sp) group of aromatic compounds. 2 The H-bond undergoes methylation to generate methyl-substituted quinone compounds. This invention offers advantages such as readily available, inexpensive, and environmentally friendly catalysts; readily available, inexpensive oxidants that do not generate hazardous waste; mild, stable, and inexpensive methylating agents; mild reaction conditions with high selectivity and high yield; widely available and stable substrates; good compatibility of substrate functional groups and a wide range of substrate applications; compatibility with complex molecules and natural products, enabling effective methylation of quinone compounds. Under optimized reaction conditions, the yield of the target product after separation can reach 80%.

The invention relates to a compound having antibacterial and antifungal properties and the chemical structure of Formula X, and to the synthesis method of said compound. Said compound is a piperazine-substituted quinone compound, and the position and orientation of the molecule within DNA and E. coli DNA gyrase B have been determined by means of molecular simulation.

The invention discloses a preparation method of sulfoalkyl (methyl) acrylate, which is characterized in that (methyl) acrylic acid and hydroxyalkyl sulfonic acid are used as raw materials, an acidic resin catalyst is adopted, and the sulfoalkyl (methyl) acrylate is prepared by reaction in the presence of a solvent and a compound polymerization inhibitor, the compound polymerization inhibitor is a combination of a phenolic compound and at least one of the following compounds (A)-(D): (A) a quinone compound; (B) a nitroxide radical compound; (C) an inorganic salt compound; and (D) copper N, N-di-n-butyl dithiocarbamate. By using the method, the polymerization side reaction in the reaction process can be effectively inhibited, and the method has the advantages of short reaction time, simple post-treatment and low content of the hydroxyalkyl sulfonic acid dimer in the product.

The invention relates to the technical field of batteries, in particular to a battery, a battery liquid leakage detection method and a power utilization device. The battery provided by the invention comprises an electrolyte and a shell for packaging the electrolyte, a first reagent is added into the electrolyte, the first reagent comprises a boron compound, the outer surface of the shell is provided with the first reagent, the first reagent comprises an anthraquinone compound, and the chemical general formula of the anthraquinone compound is shown as a formula I in the specification. Based on the fact that an anthraquinone compound can be in contact with a boron compound in an electrolyte and is subjected to a coupling reaction with the boron compound, o-diphenolic hydroxyl of the anthraquinone compound is complexed with boron to generate a fluorescent complex, if liquid leakage exists in the battery, a fluorescent color development peak of the fluorescent complex can be detected through photosensitive detection equipment, and the fluorescent color development peak of the fluorescent complex can be detected through detection equipment. Therefore, whether electrolyte leakage exists or not can be conveniently and sensitively detected.

The invention relates to the technical field of food processing, and discloses a method and a device for quickly oxidizing and coloring star anise. The method comprises the following steps: drying star anise, and performing intermittent irradiation treatment under the conditions of controlled power, temperature and humidity by adopting ultraviolet rays with a specific composite wave band to catalyze phenolic compounds in the star anise to oxidize to generate reddish brown quinone compounds so as to realize coloring. The device comprises a support, an ultraviolet irradiation module, an environment control module and an automatic control module which are arranged in a cabinet body. Through the specific ultraviolet band and process parameters, the reddish brown effect of natural oxidation for 3 months is achieved within 1 month, the conversion efficiency is remarkably improved, the storage period is shortened by 66% or above, and the storage problem that the red conversion period is long after star anise is dried is effectively solved. The method is simple and convenient in process operation and suitable for large-scale processing, and has a positive promotion effect on upgrading of the star anise industry technology.

The present application relates to naphthyl methylene quinone compounds, and preparation method and application thereof, the naphthyl methylene quinone compound has the structural formula of formula I, wherein R1 and R2 are each independently H, C 1‑18 Alkyl or C 1‑18 Cycloalkyl; R3 is H, C 1‑3 Alkyl, C 1‑3 Alkoxy, hydroxyl, nitro or carboxyl.The naphthyl methylene quinone compound of the present application has extended electronic delocalization, which is beneficial to disperse free radicals, makes the structure stable, and plays a role in the termination of free radical reaction chain.The polymerization inhibitor composition containing the naphthyl methylene quinone compound provided by the present application has excellent polymerization inhibition performance, and can be used in the industrial device for inhibiting the polymerization of double bond polymerization monomers.

A cyanobacterial quinone electrolyte preparation method and application. The present application belongs to the technical field of electrolyte preparation. The quinone compound extracted from cyanobacteria is used as the core, the electrolyte has good redox reversibility, can efficiently mediate electron transfer, significantly improves the electrochemical performance of the electrolyte, and the cyanobacterial quinone compound is derived from natural algae, has the advantages of environmental friendliness, good biocompatibility, easy availability of raw materials and low cost, compared with artificial synthetic quinone materials or other natural quinone extracts, the dispersion stability and electrochemical cycle stability in the electrolyte are more outstanding, thereby the working efficiency and service life of the electrolyte adapter device can be greatly improved.

The invention discloses a pharmaceutical composition for resisting NQO1 high-expression malignant tumors and application of the pharmaceutical composition, and relates to the technical field of medicines. When the vitamin K3, the vitamin K4 or the pharmaceutically acceptable salts thereof are combined with the quinone compounds for use, the killing sensitivity of NQO1 high-expression malignant tumor cells to the quinone compounds is obviously enhanced, and an explosive synergistic or synergistic anti-tumor effect is initiated; the killing effect of various quinone compounds on NQO1 high-expression malignant tumor cells is remarkably improved, so that the application dosage of the quinone compounds is reduced to reduce side effects, and the effect of killing NQO1 high-expression tumor cells with low dosage and high efficiency is achieved.

The invention discloses an anthraquinone compound as well as a preparation method and application thereof in resisting prostatic cancer. The structure of the anthraquinone compound 1 is shown as a formula (I). According to the present invention, the solid fermentation extract product of Aspergillus versicola SCSIO 41323 is subjected to separation and purification so as to obtain the compound Nidurufin (1), wherein the compound Nidurufin (1) is obtained from the solid fermentation extract product of Aspergillus versicola SCSIO 41323; prostate cancer cell activity evaluation finds that the compound 1 can significantly inhibit the activity of prostate cancer cells and inhibit cell proliferation, protein expression of AR, KLK3, MBOAT2 and the like can be significantly inhibited by increasing ROS activity and inducing ferroptosis of prostate cancer cells, and the Nidurfin (1) can inhibit growth of prostate cancer cells in vitro and in vivo, and can inhibit growth of prostate cancer cells in vitro and in vivo. The method is of great significance to development and utilization of deep sea abyssal and other extreme environment source microbial resources.

The present application relates to a kind of methyltransferase that can catalyze anthraquinone compound methylation, amino acid sequence is as shown in SEQ ID NO:2, also provide the application of this methyltransferase in the production of emodin-3-methyl ether and other methylated anthraquinone compounds.The present application digs a new methyltransferase, which can methylate anthraquinone compound, and can convert emodin into emodin-3-methyl ether.The present application constructs the engineering bacteria that can produce emodin-3-methyl ether using the coding gene of the enzyme, widens the methyltransferase library that can be used for emodin methylation, provides new way for emodin-3-methyl ether cell factory construction.

The invention discloses a pharmaceutical composition based on an iron-based complex and natural naphthoquinone. The pharmaceutical composition is formed by mixing a coordination polymer and a quinone compound, wherein the coordination polymer is obtained by coordinating epigallocatechin gallate and an iron element. According to the method, a coordination compound formed by natural polyphenol EGCG and Fe is combined with a quinone compound, a novel Fenton reaction system can be constructed, the system uses the quinone compound as a sustainable H2O2 supply source, H2O2 is continuously supplemented in a bacterial microenvironment through quinone redox cycle in an infected microenvironment, and the reaction time is shortened; according to the present invention, the bottleneck of insufficient H2O2 in the infected microenvironment is effectively overcome, the stable substrate is provided for the Fenton reaction, the Fenton reaction circulation is promoted by using the Fe < 3 + > reducing ability of the EGCG so as to produce Fe < 2 + >, and the synergistic interaction effect is generated between the EGCG and the Fe < 2 + > so as to achieve the continuous and efficient generation of OH, such that the removal ability on the salmonella and other drug-resistant bacteria is significantly enhanced;

The present application relates to the technical field of organic synthesis, and particularly relates to an imidazole epoxy resin curing agent and a preparation method and application thereof. The imidazole epoxy resin curing agent is prepared from the following components in parts by weight: 82-144 parts of alkyl imidazole, 108-198 parts of quinone compound and 229-342 parts of solvent. The present application connects a phenolic compound to an imidazole ring, that is, the alkyl imidazole and the quinone compound are subjected to a Michael addition reaction to generate the alkyl imidazole connected with the phenolic compound. The alkyl imidazole curing agent containing a phenolic hydroxyl group fundamentally solves the separation problem of the imidazole curing agent and the phenolic polymerization inhibitor.

The invention relates to application of pyran naphthoquinone compounds and a pharmaceutical composition for treating hepatic fibrosis, and relates to the technical field of medicines. According to the application of the pyran naphthoquinone compound, the pyran naphthoquinone compound is used for preparing a medicine for treating hepatic fibrosis; the structural formula of the pyran naphthoquinone compound is selected from a formula I or a formula II. The pyran naphthoquinone compound is found to be a novel potent anti-hepatic fibrosis compound for the first time, has the potential of being developed into an anti-hepatic fibrosis lead compound, and provides reference for mining novel anti-hepatic fibrosis drugs in traditional Chinese medicine natural products.

The invention discloses an organic lithium ion low-temperature battery positive electrode material and a preparation method and application thereof.The preparation method comprises the steps that a quinone compound containing hydroxyl and a potassium methoxide solution are subjected to a salinization reaction for 5-8 h in an ice-water bath at the temperature of 0-10 DEG C, and the molar ratio of the hydroxyl in the quinone compound to the potassium methoxide is (1-1.2): 1; the preparation method comprises the following steps: preparing a mixture through distillation, freezing, drying, ball milling and screening, dispersing and mixing the mixture, an additive and an adhesive to obtain slurry, and taking the slurry as the positive electrode material of the organic lithium ion low-temperature battery, and has the advantages that the raw materials of the positive electrode material of the organic lithium ion low-temperature battery are cheap and easy to obtain, the synthesis method is simple to operate, and the yield is high; when the material is used for a lithium ion battery system at a low temperature, extremely good charge-discharge capacity, excellent cycling stability and comprehensive electrochemical performance can be realized, and the material has a relatively good application prospect.

A class of quinones for use in the treatment of restoring, normalizing, and / or improving ATP in cells lacking mitochondria, such as red blood cells. Specific examples include use in the treatment of erythrocyte enzyme disorders, particularly deficiencies in red blood cell metabolism, such as deficiencies in the erythrocyte glycolysis pathway. This treatment increases ATP in non-mitochondrial cells. Therefore, the present invention relates to a class of quinones for use in the treatment of diseases or conditions associated with or caused by deficiencies in the erythrocyte glycolysis pathway.

The patent relates to a method for preparing marine terpenoid natural products based on a decarboxylation coupling reaction of carboxylic acid salt of sclareolide or carboxylic acid of sclareolide and quinone compounds, and belongs to the field of chemical synthesis. The method takes sclareolide as raw material, and realizes, for the first time, a Minisci decarboxylation coupling reaction of carboxylic acid salt of bicyclic sesquiterpene or carboxylic acid of sclareolide and p-benzoquinone promoted by Selectfluor, so that the synthesis steps of yahazunone are shortened from the previous 6-18 steps to 2 steps, and asymmetric synthesis of multiple yahazunone natural products is realized. The method has the characteristics of good step economy, simple operation and suitability for industrial production.

A class of quinones for use in the treatment of erythrocyte enzyme disorders. This treatment increases ATP in non-mitochondrial cells. Therefore, the present invention relates to a class of quinones for use in the treatment of diseases or conditions associated with or caused by deficiencies in the erythrocyte glycolysis pathway.

The application discloses a monoterpenoid naphthoquinone compound from a sponge co-parasitic Streptomyces, and the structure is shown as formula I: the monoterpenoid naphthoquinone compound is derived from a fermentation product of Streptomyces diacarni LHW51701.The monoterpenoid naphthoquinone compound from the sponge co-parasitic Streptomyces has simple preparation method, and has the growth inhibiting effect on methicillin-resistant Staphylococcus aureus.The application provides a new compound for marine drug research, and provides a scientific basis for developing and utilizing marine antibacterial drugs in China.

The present disclosure provides methods and uses of aminonaphthoquinone compounds in treatment and / or prevention of an optic neuropathy.

The present application relates to a method for promoting sludge thermal hydrolysis by exciting in-situ quinone compound catalytic oxidation, and belongs to the field of organic waste treatment. In the method, humic acid and other quinone compounds generated in the process of sludge high-temperature thermal hydrolysis are used as in-situ organic catalysts, and the catalytic oxidation function of the quinone compounds is excited to improve the effect of sludge thermal hydrolysis. On the premise of not affecting the effect of sludge hydrolysis, the hydrolysis temperature is reduced, the Maillard product is effectively reduced, and the quality of carbon source released by sludge hydrolysis is improved. Under the same sludge thermal hydrolysis conditions, the soluble COD concentration can be increased from 17.1 g / L to 24.3 g / L by exciting the catalytic oxidation of in-situ quinone compounds, and the increase rate is 42.1%. The method does not need to add additional catalyst, and the exciting agent is cheap metal such as ferrous ion, so the cost is low and the efficiency is high. It is a new method and new idea for improving the effect of sludge thermal hydrolysis and improving the biodegradability of hydrolyzed sludge carbon source, and it integrates sludge reduction and resource utilization, which has high application value.

The application discloses a medicinal ingredient content regulation gene of Morus notabilis and a method for identifying the same. The medicinal ingredient is a flavonoid compound or a quinone compound; wherein the genes for regulating the content of the flavonoid compound include CDL12_06902, CDL12_11941, CDL12_01396 and novel.4709; the genes for regulating the content of the quinone compound include CDL12_25459, CDL12_08649, CDL12_08581 and CDL12_16197. The application also discloses a method for identifying the medicinal ingredient content regulation gene of Morus notabilis. The genes related to the content of the flavonoid compound and the quinone compound in Morus notabilis provided by the application provide a scientific basis for metabolic regulation and molecular breeding of medicinal ingredients.

The invention discloses a green synthesis and purification method of an electroactive phenazine compound, and relates to the technical field of organic synthetic chemistry and green energy materials, and the green synthesis and purification method comprises the following steps: mixing a phenanthrenequinone compound as shown in a structural general formula (I) and an o-phenylenediamine compound as shown in a structural general formula (II) according to a molar ratio of 1: 0.9-1: 1.1, and carrying out a reaction for 2-3 hours to obtain a phenanthrenequinone compound as shown in a structural general formula (I); the preparation method comprises the following steps: taking phenazine compounds as raw materials, dissolving the phenazine compounds in an acetic acid solvent together, carrying out a condensation cyclization reaction by adopting ultrasonic irradiation under the condition of no catalyst, and after the reaction is finished, carrying out post-treatment to obtain the phenazine compounds shown in the structural general formula (III), and according to the prepared specific phenazine compounds, the molecular structure endows the substances with reversible electrochemical reduction characteristics through structural confirmation. Due to the characteristic, the compound shows potential application value in the aspect of serving as an active substance of a charge storage material, especially in the aspect of constructing a negative electrode component of an energy storage device.

A composition includes: an ultraviolet absorber; a curable compound; and an anti-fading agent, in which the ultraviolet absorber includes at least one selected from a compound represented by Formula (1) or a polymer including a structure derived from the compound represented by Formula (1), and the anti-fading agent includes at least one selected from an amine compound, a phenol compound, a hydroquinone compound, a catechol compound, an ascorbic acid compound, a carotenoid compound, a metal complex compound, or a benzolactone compound. A cured substance and an optical member, which are formed of the above-described composition.

The invention relates to the field of petrochemical engineering, in particular to a butter inhibitor as well as a preparation method and application thereof. The environment-friendly adhesive comprises the following components in parts by weight: 10-15 parts of a weak acid solvent, 1-5 parts of a complexing agent, 1-5 parts of a steric hindrance agent, 1-5 parts of a retarder, 1-5 parts of a catalyst poisoning agent, 1-5 parts of a reducing agent, 20-30 parts of a phenolic compound, 20-30 parts of an aromatic amine compound, 20-30 parts of a quinone compound, 10-15 parts of a free radical trapping agent and 5-10 parts of a bio-based raw material. Wherein the weak acid solvent can neutralize an alkaline environment, the steric hindrance agent and the retarder block a base catalysis path of a condensation reaction, the bio-based material pays more attention to environmental protection, and is halogen-free, low-toxicity and easy to degrade, and the inhibitor reduces scaling, prolongs the operation cycle of equipment and reduces the environmental protection pressure through the effects of polymerization inhibition, dispersion, metal passivation and the like.

A process for preparing a compound of formulaincluding oxidizing the triphenylmethane sulfone of formula (V) with a quinone chosen from 1,4-benzoquinone, 1,2-benzoquinone, a di(C1-C4)alkyl-1,4-benzoquinone, a di(C1-C4)alkyl-1,2-benzoquinone, a mono(C1-C4)alkyl-1,4-benzoquinone and a mono(C1-C4)alkyl-1,2-benzoquinone. A crystalline form of patent blue, sodium salt, can be achieved.