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51 results about "Colorimetric analysis" patented technology

Colorimetric analysis is a method of determining the concentration of a chemical element or chemical compound in a solution with the aid of a color reagent. It is applicable to both organic compounds and inorganic compounds and may be used with or without an enzymatic stage. The method is widely used in medical laboratories and for industrial purposes, e.g. the analysis of water samples in connection with industrial water treatment.

Application of iron-ruthenium nano-enzyme in preparation of nucleic acid detection product

The invention discloses application of iron ruthenium nano-enzyme in preparation of nucleic acid detection products, and belongs to the technical field of biological detection and nano-materials. The RIN has stable peroxidase-like (POD) activity, and can catalyze a chromogenic reaction between 3, 3 ', 5, 5'-tetramethyl benzidine (TMB) and hydrogen peroxide (H2O2). The catalytic activity of the nano-enzyme can be selectively inhibited by pyrophosphate (PPi) generated in a nucleic acid amplification reaction, so that visual colorimetric analysis on whether target nucleic acid exists or not is realized. In combination with a polymerase chain reaction (PCR) system, the invention constructs a new nucleic acid detection strategy which does not need fluorescence labeling, is simple and convenient to operate and has high sensitivity. Through verification, the system can be widely applied to rapid on-site screening and visual interpretation of related nucleic acid of drug-resistant pathogens (such as ESKAPE flora) and the like, and has a good application prospect.
Owner:BEIJING UNIV OF CHEM TECH

Peptide-modified gold nanoclusters, their preparation methods, and their application in the detection of microplastics

This invention relates to biodetection technology, disclosing a peptide-modified gold nanocluster, its preparation method, and its application in the detection of microplastics. The peptide-modified gold nanocluster comprises a gold nanocluster and a peptide LCI modified on the surface of the gold nanocluster, wherein the peptide LCI comprises an amino acid sequence as shown in SEQ ID NO: 1. The preparation method includes the following steps: providing functionalized modified gold nanoclusters; reacting the functionalized gold nanoclusters with the peptide LCI to attach the peptide LCI to the surface of the gold nanoclusters, forming the peptide-modified gold nanocluster. The microplastic detection method includes mixing the peptide-modified gold nanocluster with a test sample that may contain microplastics to obtain a detection solution, and performing colorimetric analysis or absorbance analysis on the detection solution. This gold nanocluster can specifically recognize polypropylene, exhibiting good specificity, low cost, and rapid detection of polypropylene microplastics.
Owner:NANJING NORMAL UNIVERSITY

A device for detecting pesticide residues in agricultural products

The utility model belongs to the agricultural product pesticide residue detection technical field discloses a device for detecting agricultural product pesticide residue, including base frame, the base of base frame is opened and has colorimetric card placing groove and optical magnifying glass placing groove, broken jar, broken jar includes broken jar body and the jar cover of sleeve joint installation in the top of broken jar body, the broken structure is integrated on the jar cover, conveying chamber, conveying chamber is installed in the bottom of broken jar body, and the bottom of conveying chamber is threadedly matched and is connected with filter cover, filtrate container, filtrate container can be detachably installed on the base of base frame, and filtrate container is located the just below of conveying chamber, and the base of base frame is opened and has the clamping groove corresponding with filtrate container, and the clamping groove is adapted to filtrate container. The utility model breaks through the space limit of traditional laboratory equipment by integrating the compact base frame of broken, filter, colorimetric analysis function, supports the field fast screening of field, exempts power dependence simultaneously manual operation design, reduces use cost significantly.
Owner:LIXIN NUOKANG (SHANDONG) BIOMEDICAL TECHNOLOGY CO LTD

Hg < 2 + > detection method for enhancing inherent laccase-like activity of Hg < 2 + > based on ZIF-8-Au

The invention discloses an Hg < 2 + > detection method for enhancing Hg < 2 + > intrinsic laccase-like activity based on ZIF-8-Au. The invention finds that the mercury ions have laccase-like activity, the enzyme activity of the mercury ions is obviously enhanced under the action of ZIF-8-Au, and the color of the reaction catalyzed by the mercury ions is obviously changed along with the increase of the concentration of Hg < 2 + >, so that a colorimetric analysis method for detecting the mercury ions is developed on the basis, the Turn-On type visual analysis is realized, and the application prospect is wide. The method realizes simple, rapid, sensitive and high-selectivity detection of Hg < 2 + > residues in water and food. The invention provides a new method and principle for the fields of Hg < 2 + > environment monitoring and food safety, and provides a new direction for the development of a heavy metal ion detection technology.
Owner:JIANGSU OCEAN UNIV

Fresh pesticide residue detection equipment and use method thereof

The invention discloses fresh pesticide residue detection equipment and a use method thereof, and belongs to the technical field of food safety detection. The equipment comprises a rack structure, a charging barrel structure I, a charging barrel structure II and a detection box body, and integrates the functions of cleaning, crushing, extracting, filtering, reacting, colorimetric analysis and the like. A sample is subjected to rotary spraying type cleaning through the cleaning structure, is crushed through the crushing structure, is mixed with an extraction liquid, is subjected to negative pressure suction filtration, and finally enters the detection module to complete enzyme inhibition reaction and colorimetric detection. A detection result is output in real time through a built-in display screen, an alarm is automatically given when the detection result exceeds the standard, and data are supported to be uploaded to a cloud platform. The equipment is compact in structure, high in function integration degree, simple and convenient to operate and suitable for rapidly detecting various pesticide residues in agricultural products such as vegetables and fruits on site, the detection efficiency and precision are improved, and the rapid detection requirements of basic layers and circulation links are met.
Owner:WUHAN JIAJIXIAN ECOLOGICAL AGRICULTURE DEVELOPMENT CO LTD

A smartphone-based ratiometric fluorescent sensor and its preparation method and application

The application discloses a kind of ratio fluorescent sensor based on smart phone and its preparation method and application, the preparation method includes: after mixing chloroauric acid, bovine serum albumin, sodium hydroxide, gold cluster reaction liquid is obtained;Sodium citrate, 3-aminopropyl triethoxysilane, glycerol are mixed to obtain silicon quantum dot solution;Silicon quantum dot solution, lipopolysaccharide aptamer, EDC, NHS are reacted in ultrapure water to obtain aptamer modified silicon quantum dots;Lipopolysaccharide aptamer modified silicon quantum dots and gold cluster are mixed to obtain ratio fluorescent sensor.The ratio fluorescent sensor based on smart phone prepared by the application has good stability, strong specificity, can exclude fluorescent interference in environmental matrix, and is used for lipopolysaccharide analysis and detection by combining the colorimetric analysis of color picker of smart phone, so that in-vitro naked-eye visible rapid quantitative detection of lipopolysaccharide can be realized, to meet the demand of on-site monitoring.
Owner:NANJING NORMAL UNIVERSITY

Water quality fluoride detection method based on digital image colorimetric analysis

The invention relates to the technical field of water quality detection, and discloses a water quality fluoride detection method based on digital image colorimetric analysis, which comprises the following steps: constructing a zirconium-based nano-enzyme probe, and realizing fluorine ion specific recognition through Zr-Mn bimetal coordination and boric acid modification; developing a three-layer paper-based micro-fluidic chip, a fixed zirconium-based nano-enzyme probe, an integrated optical reference array and a distributed temperature control network; multiband light source switching is cooperatively controlled through the smart phone, and reflection and fluorescence bimodal images are synchronously collected; multi-color space features are extracted, and environment parameters are fused to construct a dynamic compensation matrix to correct matrix interference; the corrected features are processed, and the fluoride concentration and the confidence interval are output; and the detection data is encrypted and then written into the block chain, and data verification and standard exceeding alarm are realized through the smart contract. The device and the method have the advantages of simplicity and convenience in operation, low cost, high portability and on-site rapid detection, and are suitable for on-site rapid detection of fluorides in various water qualities.
Owner:ZHONGWU RENJU JIANGSU ENVIRONMENTAL TESTING CO LTD

Nanoprotease with peroxidase-like activity, preparation method and application thereof

The application discloses a nano-enzyme with peroxidase-like activity and a preparation method and application thereof. The nano-enzyme has characteristic peaks of Bi2O3 in an XRD pattern; and the nano-enzyme has characteristic peaks of Fe, C, Bi and O in an XPS full spectrum. The preparation method of the nano-enzyme comprises the following steps: (1) preparing FeBiMOFs by a solvothermal method; and (2) performing thermal activation treatment on the FeBiMOFs, so that the nano-enzyme is obtained. The preparation method is simple and easy to control. The heteroatom-doped Bi2O3-based nano-enzyme has great potential when used as a peroxidase mimic to detect organic phosphorus pesticides, and the application of Bi2O3 in the sensing field is expanded. The heteroatom-doped Bi2O3-based nano-enzyme is formed by accumulation of nanoparticles with a particle size of less than 10 nm, has a large specific surface area and multiple active sites for synergistic action. When applied to a colorimetric analysis method to detect AChE and organic phosphorus pesticides (OPs) such as DDVP, the nano-enzyme has the advantages of low detection limit, wide linear range and strong anti-interference ability, and has strong practicability.
Owner:SOUTHWEST JIAOTONG UNIV +1

Saliva sample testing devices, methods, and mobile app

A method of testing a saliva sample includes: providing a testing device having a color palette and multiple test areas, using colorimetric analysis and lateral flow assay tests; collecting at least a prescribed volume of a saliva sample; dispensing, onto each of multiple test areas of a testing device, a respective portion of the collected saliva sample, the testing device thereby developing a respective discernible reaction at each test area; capturing, by a computing device, an image of testing device; analyzing, through a testing platform, the image by colorimetric and liquid flow assay analysis; and displaying results of the colorimetric analysis, the displayed results representing oral health parameters. The displayed results including quantitative indices and trend identifiers related to oral health parameters. A kit for use in conducting the above method includes the sample reactive device.
Owner:ORAL GENOME CORP

Device for measuring total phosphate in boiler water and cooling water

The utility model discloses equipment for measuring total phosphate in boiler water and cooling water, and belongs to the technical field of devices for measuring phosphate. A device for measuring total phosphate in boiler water and cooling water comprises a pipette, a colorimetric tube, a spectrophotometer, filter paper and a beaker, and further comprises a water bath kettle used for heating the colorimetric tube; the placing groove is formed in the water bath kettle, and the placing groove is used for placing a colorimetric tube; the plurality of groups of hollowed-out hole baskets are arranged in the placing groove; a filtered sample is directly added into the colorimetric tube, is digested for half an hour in a water bath environment, and then is cooled for colorimetric, so that the risks of breakage and incomplete transfer caused by directly heating a flask with open fire are effectively avoided, the accuracy of an analysis result is ensured, and the threaded column and the jacking ring can be matched with a screw rod, so that the detection accuracy is improved. Furthermore, the position of the colorimetric tube is adjusted, so that the colorimetric tubes with different lengths can be conveniently heated.
Owner:四川永盈新材料有限公司

Peritoneal dialysis fluid detection data intelligent analysis method based on visual recognition

The application provides a peritoneal dialysis liquid detection data intelligent analysis method based on visual recognition, which comprises the following steps: acquiring a test paper image to be recognized, and performing test paper region segmentation, color correction and test paper detection region brightness equalization processing on the test paper image to obtain a processed test paper detection region; acquiring a standardized color feature vector of a test paper color developing region from the test paper detection region; mapping and matching the standardized color feature vector with a standard colorimetric database to obtain a colorimetric matching value, performing color abnormality degree recognition according to the colorimetric matching value, obtaining a test paper colorimetric analysis result according to the color abnormality degree and a preset abnormal value, and performing self-adaptive correction on the test paper colorimetric analysis result with an abnormality; and constructing a personalized colorimetric model according to the colorimetric matching value combined with a historical colorimetric matching value to perform health trend analysis and early warning.
Owner:THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV +1

Systems and methods for device-independent color measurement for colorimetric sensing

A calibration method and related systems for colorimetric chemical assay and a fluid sensor apparatus using the same are provided. Reference measurements are taken from both a digital camera and a spectrometer. The digital camera is installed in the fluid sensor apparatus. Subsequently, color measurements from the digital camera are then converted and compared to prior spectrometric measurements to perform a colorimetric analysis.
Owner:MOZARC MEDICAL US LLC

A water quality fluoride detection method based on digital image colorimetric analysis

The application relates to the technical field of water quality detection, and discloses a water quality fluoride detection method based on digital image colorimetric analysis, which comprises the following steps: constructing a zirconium-based nanoscale enzyme probe, realizing specific recognition of fluorine ions through Zr-Mn bimetal coordination and boric acid modification; developing a three-layer paper-based microfluidic chip, fixing the zirconium-based nanoscale enzyme probe, integrating an optical reference array and a distributed temperature control network; synchronously collecting double-mode images of reflection and fluorescence through intelligent mobile phone collaborative control of multi-band light source switching; extracting multi-color space features, fusing environmental parameters to construct a dynamic compensation matrix to correct matrix interference; processing the corrected features to output fluoride concentration and a confidence interval; and writing the detection data into a block chain after encryption, and realizing data verification and over-limit alarm through an intelligent contract. The application has the advantages of simple operation, low cost, strong portability and on-site rapid detection, and is suitable for on-site rapid detection of various water quality fluorides.
Owner:ZHONGWU RENJU JIANGSU ENVIRONMENTAL TESTING CO LTD

A winter melon seedling salt tolerance identification method based on multi-modal features

ActiveCN121008014BTesting plants/treesHorticulture methodsBenincasa ceriferaGermplasm
The present application relates to the field of agricultural biotechnology and plant science technology, and discloses a winter melon seedling salt tolerance identification method based on multi-modal characteristics, which comprises the following steps: uniformly germinating winter melon seeds, selecting seedlings with consistent growth vigor, setting up a clear water control group and a salt stress group with a response concentration of NaCl, and collecting multi-modal data of photosynthetic fluorescence, photosynthetic absorption, colorimetric analysis and morphology at a preset time point. After the multi-modal data is standardized and normalized, it is reduced in dimension by principal component analysis, and the principal component scores are dimensionless by the membership function method. The weight is calculated by combining the contribution rate, and the comprehensive salt tolerance evaluation value is obtained by weighting. According to the comprehensive salt tolerance evaluation value, the mean value and the standard deviation, the salt tolerance is divided into six levels: normal, high resistance, medium resistance, medium sensitivity, sensitivity and high sensitivity, so that scientific identification is realized, and support is provided for winter melon salt-tolerant germplasm screening and variety breeding.
Owner:INST OF VEGETABLES GUANGDONG PROV ACAD OF AGRI SCI

Composite driving system based on combination of surfactant and cyclodextrin and application of composite driving system

The invention discloses a composite driving system based on combination of a surfactant and cyclodextrin and application of the composite driving system. The nucleic acid aggregate is formed by electrostatic adsorption and hydrophobic interaction between the cationic surface active agent and nucleic acid molecules, so that efficient enrichment of nucleic acid is realized; separation of nucleic acid is realized by separating the aggregate and the supernatant of the solution; and then cyclodextrin is added, and the charge neutralization effect of the surfactant on nucleic acid is weakened by utilizing the inclusion effect of a hydrophobic cavity of cyclodextrin on an alkyl chain of the surfactant, so that the nucleic acid aggregate is controllably released. The composite system can realize reversible enrichment of nucleic acid, is simple and convenient to operate, can be compatible with various detection means (including fluorescence, electrochemistry and colorimetric analysis), and is particularly suitable for a miniaturized and on-site nucleic acid detection platform. The invention provides a dynamic controllable nucleic acid enrichment strategy, and provides a new technical approach for rapid and sensitive molecular detection.
Owner:SOUTHEAST UNIV

An electrochemical sensor, a preparation method and application thereof in detecting sweat triglyceride content

The present application belongs to the field of analytical chemistry and electrochemistry, and particularly relates to an electrochemical sensor, a preparation method and application thereof in detection of sweat triglyceride content. A wearable sensor is prepared based on C-ZIF-67 / KB nanocomposite material, the sensor realizes detection of sweat triglyceride for the first time, and it is verified that sweat triglyceride level has high correlation with blood triglyceride level (correlation coefficient is 0.813, n=35). Through verification of a commercial colorimetric analysis kit, the sensor obtains a high correlation coefficient of 0.853 in detection of sweat triglyceride, which shows excellent accuracy.
Owner:CHINA AGRI UNIV

Preparation method and application of carbon dots for detecting carbon monoxide

The invention belongs to the technical field of gas chemical sensing and fluorescence / colorimetric analysis, and particularly discloses a preparation method and application of carbon dots for detecting carbon monoxide. The preparation method of the carbon dots for detecting carbon monoxide comprises the following steps: dissolving amino acid and copper salt in water to obtain a mixed solution; placing the mixed solution in a high-pressure reactor for heating reaction to obtain a carbon dot crude product; and purifying the carbon dot crude product to obtain the carbon dot for detecting carbon monoxide. The carbon dots prepared by the method have the advantages of simplicity in preparation, abundant surface functional groups, uniform particle size distribution, good water solubility and stability and the like, and rapid fluorescence detection of CO is realized under mild conditions; and the characteristic has a specific fluorescence and colorimetric bimodal response effect on CO, and qualitative and semi-quantitative detection of CO can be realized.
Owner:CENT SOUTH UNIV +1

A dual-function Ru / MoB MBene sensing probe, its fabrication method, sensor, and applications.

This invention relates to the field of electrochemical-colorimetric analysis and detection technology, specifically to a bifunctional Ru / MoB MBene sensing probe, its preparation method, sensor, and applications. The key technical points are: mixing surface-modified Ru with a two-dimensional MoB MBene nanosheet suspension, and preparing a Ru / MoB MBene composite material via electrostatic self-assembly as a bifunctional sensing probe. This probe is used to construct an electrochemical-colorimetric dual-mode sensor, employing a dual-mode signal output strategy to fully leverage the advantages of electrochemical methods in terms of sensitivity, linear range, and precise quantification. It also integrates rapid colorimetric visualization and on-site screening capabilities. The two modes can operate independently or mutually verify each other, significantly improving the reliability of detection results, resistance to matrix interference, and practical applicability. This overcomes the problems of poor portability, long detection cycles, and insufficient sensitivity to trace micro / nanoplastics found in traditional equipment.
Owner:YUNNAN UNIV

A method for identifying defects in photomasks

This invention discloses a method for identifying photomask defects, belonging to the field of photomask inspection technology. The method includes: S1, acquiring a surface defect image; S2, preprocessing the surface defect image based on the imaging characteristics of the defect; S3, correcting the preprocessed surface defect image using a filtering algorithm; S4, performing colorimetric analysis on the corrected surface defect image to obtain particle regions; S5, segmenting the particle regions based on the morphological features of the defect to obtain defect islands; S6, performing morphological analysis on the defect islands to obtain the defect type and size. The photomask defect identification method provided by this invention automatically processes surface defect images and extracts defect islands by combining morphological and colorimetric analysis methods, improving the accuracy of defect identification, overcoming the limitations of differences in imaging systems across different devices, achieving automatic batch processing, and saving manpower and material resources in mass production.
Owner:青岛方益技术有限公司

Manganese-matrix nano-enzyme, preparation method thereof and application of manganese-matrix nano-enzyme in colorimetric analysis of glyphosate residues in tobacco shreds

The preparation method comprises the following steps: mixing a zinc salt aqueous solution with a 2-methylimidazole aqueous solution to prepare ZIF-8 nano-particles, dispersing the ZIF-8 nano-particles into an alcoholic solution to obtain a ZIF-8 alcoholic solution, mixing the ZIF-8 alcoholic solution with a polyphenol aqueous solution, and carrying out colorimetric analysis on the ZIF-8 alcoholic solution to obtain the manganese-based nano-enzyme. The preparation method comprises the following steps: preparing polyphenol cross-linked ZIF-8 nano-particles, dispersing the polyphenol cross-linked ZIF-8 nano-particles into water to obtain a polyphenol cross-linked ZIF-8 aqueous solution, and mixing the polyphenol cross-linked ZIF-8 aqueous solution with a potassium permanganate aqueous solution to obtain the manganese-based nano-enzyme. The method comprises the following steps: mixing 2, 4-dichlorophenol, 4-aminoantipyrine and manganese-based nano-enzyme, adding a buffer solution to obtain a mixed solution, mixing a tobacco shred leachate with the mixed solution to obtain a reaction solution, and rapidly detecting glyphosate in tobacco shreds by observing the color change of a reaction system and the change of an ultraviolet absorbance value. The method saves a lot of time for detecting the glyphosate in the tobacco shreds.
Owner:CHINA TOBACCO ZHEJIANG IND CO LTD

Platinum-loaded cerium-based nanoscale enzyme, and preparation method and application thereof

PendingCN122377461APlatinum nanoclustersCerium(IV) oxide
The application discloses a kind of platinum supported cerium-based nanoscale enzyme and its preparation and application, the nanoscale enzyme includes cerium oxide nanorod carrier and the Pt active component loaded on its surface, the Pt active component is dispersed in the form of single atom or nanocluster on the surface of cerium oxide nanorod, the surface of cerium oxide nanorod has oxygen defect, by first loading platinum monolayer on the surface of cerium dioxide nanorod, then by reduction treatment, platinum atom forms platinum nanocluster on the surface of cerium dioxide and obtains.The nanoscale enzyme of the application effectively adjusts the oxygen vacancy and Pt site on the surface of cerium dioxide, has good peroxidase-like characteristics, can be used to construct TMB colorimetric system for colorimetric analysis of thiol reducing substances, and further used for disease screening, significantly improves the distinguishing effect.
Owner:NANJING NORMAL UNIVERSITY

PtPdCuFe alloy nano-enzyme and colorimetric sensor and application thereof

The invention discloses a PtPdCuFe alloy nano enzyme material, and belongs to the technical field of nano materials and analytical chemistry. According to the technical key points, four metal atoms of platinum, palladium, copper and iron are uniformly distributed on the nanoscale to form an alloy structure, and the unique quaternary composition and atomic-scale mixing generate a synergistic effect, so that the catalyst has excellent oxidase-like and peroxidase-like activities at the same time. The invention also discloses a colorimetric sensor containing the material, and a method for detecting in a buffer system through catalytic oxidation and coupling with nitrite by using the oxidase-like activity of the material. According to the method, the peroxidase-like activity of the material is utilized, and TMB oxidation is inhibited through thiophanate-methyl in the presence of hydrogen peroxide for detection. The invention further discloses a method for synthesizing the quaternary alloy material through a one-step hydrothermal method. The method is mainly used for high-sensitivity and high-selectivity rapid colorimetric analysis of nitrite pollutants and thiophanate-methyl pesticide residues in food and environmental samples.
Owner:GUANGXI TEACHERS EDUCATION UNIV

A colorimetric analysis method of ion concentration test paper suitable for mobile phone app

The application discloses a colorimetric analysis method of ion concentration detection test paper suitable for mobile phone App and belongs to the technical field of test paper colorimetric analysis. The application obtains pictures of a test paper reference color block and a reagent block after reaction with a to-be-detected ion solution through a camera, guarantees the quality of the collected images through user operation guidance, carries out color correction of the test paper image, detects and extracts a ROI area image of the reference color block based on contour shape features, carries out reagent block ROI area image positioning and extraction based on collinearity and congruent shape of the reference color block, then extracts color information of the color developing area of the test paper reference color block and the reagent block, and further calculates color similarity in RGB, HSV and Lab color spaces based on the color information and carries out test paper color identification according to a voting mechanism. The method can provide convenience for patients with color vision deficiency, has certain self-adaptation to different illumination environments, can reduce the influence of subjectivity on the accuracy of detection results, and is simple and fast in the detection process.
Owner:JILIN UNIVERSITY

Online colorimetric analysis system

The invention discloses an online colorimetric analysis system, and solves the technical problems of poor timeliness and non-ideal precision in the prior art. The system comprises a colorimeter flow cell which is led out from the high-pressure side of a process main pipeline and is connected to the low-pressure side of the process main pipeline, a sight glass arranged on the colorimeter flow cell, and an optical chromaticity measuring device which is arranged on the colorimeter flow cell, is positioned at the sight glass and is used for detecting the chromaticity of a medium to be measured in the colorimeter flow cell. The device is simple in structure, scientific and reasonable in design and convenient to implement, has the characteristics of high timeliness, high data precision, convenience in management and the like compared with a traditional chromaticity measurement scheme, can effectively save time and labor cost, and has a certain popularization prospect.
Owner:CHINA CHENGDA ENG

A preparation method of a nanomaterial for detecting alpha-glucosidase activity

The application discloses a preparation method of Mo-based nanomaterial for detecting alpha-glucosidase (alpha-Glu), which comprises the following steps: firstly, synthesizing MoO3 by taking MoS2 and H2O2 as raw materials; and then bonding a small molecule containing a mercapto group with Mo atoms in the MoO3 as a ligand to prepare non-stoichiometric molybdenum oxide MoO 3‑x The material has a characteristic localized surface plasmon resonance (LSPR) effect, shows excellent optical properties, and presents a typical blue solution. In addition, the material has sensitive response characteristics to H2O2, and can be used for H2O2 detection and H2O2 generation related enzyme cascade analysis. Based on the above-mentioned blue color and H2O2 response characteristics, colorimetric analysis of alpha-Glu and its inhibitors can be further realized, and excellent sensitivity and selectivity are achieved.
Owner:SUZHOU 30 BILLION TECH CO LTD

A catheterization system for ease of care

This invention relates to the field of medical device technology, and in particular to a convenient urinary catheterization system, comprising: a urinary catheter, a siphon structure, and a monitoring component. The system uses a urine conductivity sensor to monitor changes in urine conductivity in real time. When the conductivity reaches a preset threshold, it automatically triggers a test strip structure capable of continuously detecting urine to perform a urine test. A color acquisition unit reads the test strip color and generates a urine property report. This avoids the problem of test strips becoming ineffective due to prolonged soaking and achieves complete monitoring from infection risk warning to infection indicator diagnosis, significantly improving both accuracy and timeliness. The automatically triggered test strip detection replaces nurses' manual visual observation and colorimetric analysis, greatly reducing the frequency of nurses visiting wards to check urine bags, record urine volume, and determine urine characteristics. This frees nurses from tedious, repetitive tasks, allowing them to devote more energy to clinical professional care.
Owner:SHANXI BETHUNE HOSPITAL (SHANXI ACAD OF MEDICAL SCI SHANXI HOSPITAL OF TONGJI HOSPITAL AFFILIATED TO TONGJI MEDICAL COLLEGE OF HUAZHONG UNIV OF SCI & TECH SHANXI MEDICAL UNIV THIRD HOSPITAL SHANXI MEDICAL UNIV THIRD CLINICAL COLLEGE OF MEDICINE)

Construction method and application of colorimetric and light-enhanced electrochemical dual-mode aptasensor based on bifunctional probe

The present application belongs to the technical field of biosensor, and particularly relates to a construction method of a colorimetric-light enhanced electrochemical dual-mode aptamer sensor based on a bifunctional probe and application thereof. The present application obtains a double signal channel of a probe methylene blue (MB) by using a streptavidin magnetic bead, and obtains supernatant with color recognition for colorimetric analysis through specific release of MB at the interface of the magnetic bead. The electron transfer path of a reduced graphene oxide-gold nanometer Schottky junction is studied, and the photo-generated electron promotes the redox process of MB, so that electrochemical signal amplification is realized. Higher response sensitivity can be obtained based on light excitation signal amplification for AFB1 trace analysis, and self-checking can be performed through I MB signals before and after light excitation to improve the reliability and accuracy of detection. Through rapid qualitative and accurate quantitative analysis of AFB1, early warning and accurate monitoring of agricultural sample mildew analysis can be realized.
Owner:JIANGSU UNIV

Application of high-entropy sulfide nanoscale enzyme material in colorimetric analysis for detection of sulfadiazine

The application belongs to the technical field of colorimetric detection, and particularly relates to application of a high-entropy sulfide nano-enzyme material in colorimetric analysis and detection of sulfadiazine. The application uses metal nitrates of Fe, Co, Cu, Cr and Zr and TAA as raw materials to synthesize a five-element high-entropy sulfide nano-enzyme material (F3CZ-48). The F3CZ-48 is used as a colorimetric analysis and detection method with peroxidase activity based on tetramethyl benzidine (TMB) as a chromogenic substrate, and a new method for detecting sulfadiazine (SD) is established. The F3CZ-48 has high stability, easy storage, low cost, excellent catalytic performance and rich reaction sites. By fitting the change of UV-Vis intensity with the concentration of SD, a linear calibration curve with a correlation coefficient of 0.993 is obtained, and the detection limit is 0.121 muM (S / N=3). The material has good sensitivity, selectivity and reproducibility for colorimetric detection of SD, and provides a new scheme for designing a new catalyst for detecting SD.
Owner:LIAONING UNIVERSITY

Benzene quinone components in arnebia euchroma, extraction and separation method thereof and application thereof in antitumor drugs

This invention relates to the field of Lithospermum erythrorhizon isolation and purification technology, specifically a method for extracting and separating benzoquinone components from Lithospermum erythrorhizon in Xinjiang, and its application in antitumor drugs. The method involves extracting and concentrating the dried roots of Lithospermum erythrorhizon by ethanol reflux. The concentrated extract is then further extracted and concentrated. The resulting petroleum ether fraction is subjected to chromatographic separation and gradient elution, followed by colorimetric analysis. Ten similar components are combined. The first concentrate is then separated, subjected to gradient elution, and subjected to colorimetric analysis, resulting in the combination of seven similar components. The second concentrate is then separated, subjected to gradient elution, and subjected to colorimetric analysis, resulting in the combination of nine similar components. The third concentrate is then separated and purified to obtain the final product. This invention features a simple process, environmental friendliness, and high product purity. It is the first time that benzoquinone components from Lithospermum erythrorhizon in Xinjiang have been obtained. In vitro activity verification has shown that these components exhibit inhibitory activity against HeLa tumor cells, and they can be applied to the extraction and separation of drugs for the prevention and / or anti-cervical cancer.
Owner:PEOPLES HOSPITAL OF XINJIANG UYGUR AUTONOMOUS REGION