28 results about "Colorimetric analysis" patented technology

The utility model belongs to the agricultural product pesticide residue detection technical field discloses a device for detecting agricultural product pesticide residue, including base frame, the base of base frame is opened and has colorimetric card placing groove and optical magnifying glass placing groove, broken jar, broken jar includes broken jar body and the jar cover of sleeve joint installation in the top of broken jar body, the broken structure is integrated on the jar cover, conveying chamber, conveying chamber is installed in the bottom of broken jar body, and the bottom of conveying chamber is threadedly matched and is connected with filter cover, filtrate container, filtrate container can be detachably installed on the base of base frame, and filtrate container is located the just below of conveying chamber, and the base of base frame is opened and has the clamping groove corresponding with filtrate container, and the clamping groove is adapted to filtrate container. The utility model breaks through the space limit of traditional laboratory equipment by integrating the compact base frame of broken, filter, colorimetric analysis function, supports the field fast screening of field, exempts power dependence simultaneously manual operation design, reduces use cost significantly.

The invention discloses an Hg < 2 + > detection method for enhancing Hg < 2 + > intrinsic laccase-like activity based on ZIF-8-Au. The invention finds that the mercury ions have laccase-like activity, the enzyme activity of the mercury ions is obviously enhanced under the action of ZIF-8-Au, and the color of the reaction catalyzed by the mercury ions is obviously changed along with the increase of the concentration of Hg < 2 + >, so that a colorimetric analysis method for detecting the mercury ions is developed on the basis, the Turn-On type visual analysis is realized, and the application prospect is wide. The method realizes simple, rapid, sensitive and high-selectivity detection of Hg < 2 + > residues in water and food. The invention provides a new method and principle for the fields of Hg < 2 + > environment monitoring and food safety, and provides a new direction for the development of a heavy metal ion detection technology.

The utility model discloses equipment for measuring total phosphate in boiler water and cooling water, and belongs to the technical field of devices for measuring phosphate. A device for measuring total phosphate in boiler water and cooling water comprises a pipette, a colorimetric tube, a spectrophotometer, filter paper and a beaker, and further comprises a water bath kettle used for heating the colorimetric tube; the placing groove is formed in the water bath kettle, and the placing groove is used for placing a colorimetric tube; the plurality of groups of hollowed-out hole baskets are arranged in the placing groove; a filtered sample is directly added into the colorimetric tube, is digested for half an hour in a water bath environment, and then is cooled for colorimetric, so that the risks of breakage and incomplete transfer caused by directly heating a flask with open fire are effectively avoided, the accuracy of an analysis result is ensured, and the threaded column and the jacking ring can be matched with a screw rod, so that the detection accuracy is improved. Furthermore, the position of the colorimetric tube is adjusted, so that the colorimetric tubes with different lengths can be conveniently heated.

The application relates to the technical field of water quality detection, and discloses a water quality fluoride detection method based on digital image colorimetric analysis, which comprises the following steps: constructing a zirconium-based nanoscale enzyme probe, realizing specific recognition of fluorine ions through Zr-Mn bimetal coordination and boric acid modification; developing a three-layer paper-based microfluidic chip, fixing the zirconium-based nanoscale enzyme probe, integrating an optical reference array and a distributed temperature control network; synchronously collecting double-mode images of reflection and fluorescence through intelligent mobile phone collaborative control of multi-band light source switching; extracting multi-color space features, fusing environmental parameters to construct a dynamic compensation matrix to correct matrix interference; processing the corrected features to output fluoride concentration and a confidence interval; and writing the detection data into a block chain after encryption, and realizing data verification and over-limit alarm through an intelligent contract. The application has the advantages of simple operation, low cost, strong portability and on-site rapid detection, and is suitable for on-site rapid detection of various water quality fluorides.

The invention discloses a composite driving system based on combination of a surfactant and cyclodextrin and application of the composite driving system. The nucleic acid aggregate is formed by electrostatic adsorption and hydrophobic interaction between the cationic surface active agent and nucleic acid molecules, so that efficient enrichment of nucleic acid is realized; separation of nucleic acid is realized by separating the aggregate and the supernatant of the solution; and then cyclodextrin is added, and the charge neutralization effect of the surfactant on nucleic acid is weakened by utilizing the inclusion effect of a hydrophobic cavity of cyclodextrin on an alkyl chain of the surfactant, so that the nucleic acid aggregate is controllably released. The composite system can realize reversible enrichment of nucleic acid, is simple and convenient to operate, can be compatible with various detection means (including fluorescence, electrochemistry and colorimetric analysis), and is particularly suitable for a miniaturized and on-site nucleic acid detection platform. The invention provides a dynamic controllable nucleic acid enrichment strategy, and provides a new technical approach for rapid and sensitive molecular detection.

The present application belongs to the field of analytical chemistry and electrochemistry, and particularly relates to an electrochemical sensor, a preparation method and application thereof in detection of sweat triglyceride content. A wearable sensor is prepared based on C-ZIF-67 / KB nanocomposite material, the sensor realizes detection of sweat triglyceride for the first time, and it is verified that sweat triglyceride level has high correlation with blood triglyceride level (correlation coefficient is 0.813, n=35). Through verification of a commercial colorimetric analysis kit, the sensor obtains a high correlation coefficient of 0.853 in detection of sweat triglyceride, which shows excellent accuracy.

This invention relates to the field of electrochemical-colorimetric analysis and detection technology, specifically to a bifunctional Ru / MoB MBene sensing probe, its preparation method, sensor, and applications. The key technical points are: mixing surface-modified Ru with a two-dimensional MoB MBene nanosheet suspension, and preparing a Ru / MoB MBene composite material via electrostatic self-assembly as a bifunctional sensing probe. This probe is used to construct an electrochemical-colorimetric dual-mode sensor, employing a dual-mode signal output strategy to fully leverage the advantages of electrochemical methods in terms of sensitivity, linear range, and precise quantification. It also integrates rapid colorimetric visualization and on-site screening capabilities. The two modes can operate independently or mutually verify each other, significantly improving the reliability of detection results, resistance to matrix interference, and practical applicability. This overcomes the problems of poor portability, long detection cycles, and insufficient sensitivity to trace micro / nanoplastics found in traditional equipment.

This invention discloses a method for identifying photomask defects, belonging to the field of photomask inspection technology. The method includes: S1, acquiring a surface defect image; S2, preprocessing the surface defect image based on the imaging characteristics of the defect; S3, correcting the preprocessed surface defect image using a filtering algorithm; S4, performing colorimetric analysis on the corrected surface defect image to obtain particle regions; S5, segmenting the particle regions based on the morphological features of the defect to obtain defect islands; S6, performing morphological analysis on the defect islands to obtain the defect type and size. The photomask defect identification method provided by this invention automatically processes surface defect images and extracts defect islands by combining morphological and colorimetric analysis methods, improving the accuracy of defect identification, overcoming the limitations of differences in imaging systems across different devices, achieving automatic batch processing, and saving manpower and material resources in mass production.

The application discloses a kind of platinum supported cerium-based nanoscale enzyme and its preparation and application, the nanoscale enzyme includes cerium oxide nanorod carrier and the Pt active component loaded on its surface, the Pt active component is dispersed in the form of single atom or nanocluster on the surface of cerium oxide nanorod, the surface of cerium oxide nanorod has oxygen defect, by first loading platinum monolayer on the surface of cerium dioxide nanorod, then by reduction treatment, platinum atom forms platinum nanocluster on the surface of cerium dioxide and obtains.The nanoscale enzyme of the application effectively adjusts the oxygen vacancy and Pt site on the surface of cerium dioxide, has good peroxidase-like characteristics, can be used to construct TMB colorimetric system for colorimetric analysis of thiol reducing substances, and further used for disease screening, significantly improves the distinguishing effect.

The invention discloses a PtPdCuFe alloy nano enzyme material, and belongs to the technical field of nano materials and analytical chemistry. According to the technical key points, four metal atoms of platinum, palladium, copper and iron are uniformly distributed on the nanoscale to form an alloy structure, and the unique quaternary composition and atomic-scale mixing generate a synergistic effect, so that the catalyst has excellent oxidase-like and peroxidase-like activities at the same time. The invention also discloses a colorimetric sensor containing the material, and a method for detecting in a buffer system through catalytic oxidation and coupling with nitrite by using the oxidase-like activity of the material. According to the method, the peroxidase-like activity of the material is utilized, and TMB oxidation is inhibited through thiophanate-methyl in the presence of hydrogen peroxide for detection. The invention further discloses a method for synthesizing the quaternary alloy material through a one-step hydrothermal method. The method is mainly used for high-sensitivity and high-selectivity rapid colorimetric analysis of nitrite pollutants and thiophanate-methyl pesticide residues in food and environmental samples.

This invention relates to the field of medical device technology, and in particular to a convenient urinary catheterization system, comprising: a urinary catheter, a siphon structure, and a monitoring component. The system uses a urine conductivity sensor to monitor changes in urine conductivity in real time. When the conductivity reaches a preset threshold, it automatically triggers a test strip structure capable of continuously detecting urine to perform a urine test. A color acquisition unit reads the test strip color and generates a urine property report. This avoids the problem of test strips becoming ineffective due to prolonged soaking and achieves complete monitoring from infection risk warning to infection indicator diagnosis, significantly improving both accuracy and timeliness. The automatically triggered test strip detection replaces nurses' manual visual observation and colorimetric analysis, greatly reducing the frequency of nurses visiting wards to check urine bags, record urine volume, and determine urine characteristics. This frees nurses from tedious, repetitive tasks, allowing them to devote more energy to clinical professional care.

The present application belongs to the technical field of biosensor, and particularly relates to a construction method of a colorimetric-light enhanced electrochemical dual-mode aptamer sensor based on a bifunctional probe and application thereof. The present application obtains a double signal channel of a probe methylene blue (MB) by using a streptavidin magnetic bead, and obtains supernatant with color recognition for colorimetric analysis through specific release of MB at the interface of the magnetic bead. The electron transfer path of a reduced graphene oxide-gold nanometer Schottky junction is studied, and the photo-generated electron promotes the redox process of MB, so that electrochemical signal amplification is realized. Higher response sensitivity can be obtained based on light excitation signal amplification for AFB1 trace analysis, and self-checking can be performed through I MB signals before and after light excitation to improve the reliability and accuracy of detection. Through rapid qualitative and accurate quantitative analysis of AFB1, early warning and accurate monitoring of agricultural sample mildew analysis can be realized.

The application belongs to the technical field of colorimetric detection, and particularly relates to application of a high-entropy sulfide nano-enzyme material in colorimetric analysis and detection of sulfadiazine. The application uses metal nitrates of Fe, Co, Cu, Cr and Zr and TAA as raw materials to synthesize a five-element high-entropy sulfide nano-enzyme material (F3CZ-48). The F3CZ-48 is used as a colorimetric analysis and detection method with peroxidase activity based on tetramethyl benzidine (TMB) as a chromogenic substrate, and a new method for detecting sulfadiazine (SD) is established. The F3CZ-48 has high stability, easy storage, low cost, excellent catalytic performance and rich reaction sites. By fitting the change of UV-Vis intensity with the concentration of SD, a linear calibration curve with a correlation coefficient of 0.993 is obtained, and the detection limit is 0.121 muM (S / N=3). The material has good sensitivity, selectivity and reproducibility for colorimetric detection of SD, and provides a new scheme for designing a new catalyst for detecting SD.

This invention relates to the field of Lithospermum erythrorhizon isolation and purification technology, specifically a method for extracting and separating benzoquinone components from Lithospermum erythrorhizon in Xinjiang, and its application in antitumor drugs. The method involves extracting and concentrating the dried roots of Lithospermum erythrorhizon by ethanol reflux. The concentrated extract is then further extracted and concentrated. The resulting petroleum ether fraction is subjected to chromatographic separation and gradient elution, followed by colorimetric analysis. Ten similar components are combined. The first concentrate is then separated, subjected to gradient elution, and subjected to colorimetric analysis, resulting in the combination of seven similar components. The second concentrate is then separated, subjected to gradient elution, and subjected to colorimetric analysis, resulting in the combination of nine similar components. The third concentrate is then separated and purified to obtain the final product. This invention features a simple process, environmental friendliness, and high product purity. It is the first time that benzoquinone components from Lithospermum erythrorhizon in Xinjiang have been obtained. In vitro activity verification has shown that these components exhibit inhibitory activity against HeLa tumor cells, and they can be applied to the extraction and separation of drugs for the prevention and / or anti-cervical cancer.

The invention relates to an on-tree palm fruit maturity detection method and device based on target segmentation and colorimetric analysis, equipment and a medium, and the method comprises the steps: updating a backbone network of a first maturity detection model to a StarNet framework, updating all C2F modules in the backbone network and a neck network to C2F-Star modules, a detection head network is updated to be a lightweight shared convolution detection head, an original CIOU loss function is updated to be a DIOU loss function to construct a second maturity detection model, and a C2F-Star module is used for updating a Bottleneck structure in an original C2F module to be a Star Block module; and inputting a to-be-detected palm fruit image into the second maturity detection model, outputting a polygon mask corresponding to each target palm fruit, counting a red pixel proportion in a polygon mask area, and determining a maturity category corresponding to each target palm fruit according to the red pixel proportion. According to the method, the target can be stably identified even in the scenes of interlaced branches and overlapped leaves, and the problem of detection failure caused by shielding is solved.

An apparatus comprises a barrel and a colorimetric assay assembly. The barrel has a sidewall defining a portion of a colorimetric chamber that is in fluid communication with an internal chamber defined by an inner surface. The colorimetric assay assembly, housed in the colorimetric chamber, comprises a sample application pad to receive a fluid sample and a colorimetric detection pad to visualize a presence of free hemoglobin. The sample application pad is formed of a prefiltration layer and a filtration layer. The prefiltration layer comprises a distal surface having a first wetting property and a hydrophilic receiving surface having a second wetting property less than the first wetting property and is configured to receive the fluid sample and convey at least a portion of the fluid sample to the filtration layer. The filtration layer is porous to plasma and the free hemoglobin and not porous to red blood cells.

The utility model discloses an environment-friendly sulfuric acid colorimetric analysis device which comprises a supporting table, a compressor and a condenser are fixedly installed at the bottom end in the supporting table, the condenser is located behind the compressor, and a control terminal is fixedly installed on the left side of the top of the supporting table. A heating bath tank and a condensation bath tank are arranged on the right side of the top of the supporting table, the heating bath tank is located in front of the condensation bath tank, a hot bath stirring paddle and a hot bath heating rod are installed at the bottom end of the interior of the heating bath tank, and the hot bath heating rod is located at the side end of the hot bath stirring paddle; a cold bath stirring paddle and a cold bath heating rod are installed at the bottom end of the interior of the condensation bath tank, the cold bath heating rod is located at the side end of the cold bath stirring paddle, and a movable support is fixedly installed at the top end, close to the condensation bath tank, of the supporting table. Through the arrangement of the titration pump and the movable bracket, the aim of providing a stable temperature environment for uniform titration is fulfilled.

The invention discloses an optical metasurface chip for label-free colorimetric analysis of pathological tissue slices. The optical metasurface chip comprises a chip substrate and a two-dimensional periodic nanostructure on the substrate. The two-dimensional periodic nanostructure can generate a structural colored light signal under the irradiation of white light, the light signal can be directly observed under a common optical microscope, and the color of the light signal is changed along with the change of the refractive index of a biological tissue slice attached to the surface of the light signal, so that the label-free colorimetric analysis of tumor tissue types and differentiation grades is realized. The method does not need dyeing or expensive equipment, is simple and convenient to operate and rapid in analysis, and is suitable for intraoperative rapid diagnosis and fine pathological evaluation of various cancers such as liver cancer and intestinal cancer.

The present application relates to a SERS biosensor, which is a hairpin probe DNA modified on the surface of small-particle-size AuNPs, and a protective DNA and a Raman dye modified on the surface of large-particle-size AuNPs; an aptamer, trigger chain 1 and 2 are combined into a triple-stranded structure; then the target bacteria and exonuclease III are mixed and added for enzymatic reaction, finally a SERS hot spot is generated and a very strong SERS signal is generated, the supernatant is taken for SERS detection, and the rapid detection of the target bacteria-methicillin-resistant Staphylococcus aureus can be realized. The present application combines the traditional colorimetric analysis method and multi-stage nucleic acid amplification together, can quickly convert the trace target signal into Raman signal output through multi-stage signal amplification, and realizes the specific early rapid detection of the target bacteria.

This invention relates to a testing method for evaluating the makeup removal ability of liquid makeup removers. The testing method requires materials including a biomimetic silicone sheet, soft cotton makeup remover wipes, a weighting device, and a pulling mechanism. The required equipment includes a coating device for evenly applying the product to be removed and a colorimeter for colorimetric analysis. The testing method of this invention is scientifically sound, convenient, and efficient. It can intuitively and effectively demonstrate the makeup removal ability of the tested product. Furthermore, due to the simplicity, ease of assembly, and lightweight portability of its testing equipment, it can effectively adapt to various testing needs and possesses broad applicability. Utilizing standardized test templates and instruments ensures the standardization and accuracy of the test, not only visually demonstrating the makeup removal ability but also providing precise data results, effectively improving the accuracy and reliability of the test.

This invention discloses a colorimetric card for early warning drainage fluid, comprising a card body, a colorimetric area, a central hollow area, an elastic fitting structure, a light-shielding structure, a time-recording structure, an independent detection piece, and sealed packaging. The card body has a colorimetric area and a central hollow area. The colorimetric area includes a normal zone, an infection warning zone, and a severe infection zone. The elastic fitting structure is located on the back of the card body, allowing the card body to conform to the curved surface of the drainage bag. The light-shielding structure is an extension of the card body, blocking external ambient light during colorimetric analysis. The time-recording structure includes a preset time node area and a blank supplement area, meeting the flexible monitoring needs of different drainage times in various departments. The independent detection piece is independent of the card body, with a pH detection element mounted on it, and is individually packaged in sealed packaging. This invention is applicable to drainage fluid monitoring in multiple clinical departments, including general surgery, hepatobiliary surgery, neurosurgery, urology, thoracic surgery, and obstetrics and gynecology. The colorimetric unit corresponds to CMYK values, RGB values, or Pantone color codes, allowing a color difference tolerance of ±5%. The beneficial effects of this invention are: direct observation of liquid color through the drainage bag; elastic fit structure design to fit the curved surface; light shielding structure to reduce ambient light interference; standardized color measurement to ensure batch consistency; flexible time recording to meet the needs of various departments; and independent pH detection strips for flexible and convenient testing.

The utility model discloses a portable detection device for two -way lateral flow chromatography test paper strip, including box, box cover, color developing agent drop adding mechanism, controller, camera, carousel and test paper mechanism, color developing agent drop adding mechanism, controller and camera all set up in the box, and the controller is electrically connected with camera, be equipped with detection room in the box, and the detection room is equipped with the opening in the one side of box, and the carousel rotation sets up in the detection room, and the test paper mechanism sets up on the carousel, and the camera and color developing agent drop adding mechanism all are located carousel top. The technical effect for reaching is: adopt built -in camera, and the distance, focal length of shooting some setting parameters are fixed, effectively avoid the error caused because of the difference of shooting condition, make LFIA colorimetric analysis result more accurate, be equipped with color developing agent drop adding mechanism, can realize the automatic addition of color developing agent, be convenient for positioning quantitative addition color developing agent, avoid the error caused by manual addition.

This invention discloses a method and application for colorimetric analysis of antibiotics using a paper-based detection chip. The method includes: preparing a paper-based detection unit; immersing the paper-based detection unit in a NiCo@C HNs solution modified with nucleic acid aptamers; drying to obtain a paper-based detection chip; adding samples containing different concentrations of antibiotics for reaction; then adding a solution containing TMB and H2O2 for colorimetric reaction; using a mobile phone to identify color intensity to obtain RGB or grayscale values; selecting the linear curve with the highest fitting degree between antibiotic concentration and RGB or grayscale values ​​as the antibiotic detection standard curve; and then quantitatively detecting the antibiotic content based on the RGB or grayscale values ​​of the measured sample. Antibiotics can also be qualitatively detected based on colorimetric analysis. This method has advantages such as low cost, simple operation, fast response, strong anti-interference ability, and on-site detection capability, and can be applied to the detection of antibiotic residues in the environment and food.

The invention develops a dual-mode optical sensor based on CuO2 nanodots. The dual-mode optical sensor is mainly applied to detection and research of a Warburg effect of gastric cancer. The CuO2 nanodots can catalyze the reaction of o-phenylenediamine (OPD) and hydrogen peroxide (H2O2), so that the color of the solution is changed from colorless to yellow along with the increase of absorbance and fluorescence intensity. Based on the reaction, a dual-mode sensor is designed, and the activity of lactic acid and lactate oxidase is synchronously detected through colorimetry and fluorescence. In the process of catalyzing lactic acid to generate H2O2 by lactic acid oxidase, the generated H2O2 promotes the color of a solution to change remarkably, so that the sensitive detection of the activity of lactic acid and oxidase thereof is indirectly realized. As the Warburg effect of the gastric cancer causes rise of the lactic acid level, the sensor can effectively associate the lactic acid level with the metabolic characteristics of the gastric cancer. In addition, in combination with an RGB colorimetric analysis technology, a smart phone is used for capturing color changes and carrying out image quantitative analysis, a portable, low-cost and high-sensitivity detection system is formed, and the application blank of the CuO2 nanodots in the field is filled up.

Disclosed are a system and method for enhancing the visualization, classification, and / or interpretation of a photonic readout of a colorimetric assay. The colorimetric assay is associated with a defined color spectrum that includes a positive region indicative of positive test results and a negative region indicative of negative test results. The system and method operate to receive an image of the photonic readout, convert the image to a predefined color space, enhance image saturation and hue, and adjust a brightness level of the image. The system and method increase visual contrast between the negative and positive regions of the color spectrum specific to the colorimetric assay, making the readout easier to interpret for both users with normal vision and users with variations of color weakness or blindness.

The invention discloses a bipolar electrode-electrochemical luminescence biosensor for detecting a myeloid thyroid carcinoma M918T mutant gene. The preparation method comprises the following steps: preparing a g-C3N4-coated FeMOFs nano-enzyme compound from graphite phase carbon nitride (g-C3N4) and an iron metal organic framework (FeMOFs), and constructing the dual-mode BPE-ECL biosensor based on the nano-enzyme and a 2 '-FN monomer modified probe. When a target gene exists, the g-C3N4atFeMOFs catalyzes H2O2 reduction, so that an ECL signal of Ru (bpy) 32 + / TPrA at a BPE anode is increased, and the ECL signal is quantitatively related to a cathode H2O2 reduction process. Meanwhile, 3, 3 ', 5, 5'-tetramethyl benzidine is converted into a blue oxidation product by the nano-enzyme under the action of H2O2, and colorimetric analysis is carried out through an RGB mode of a smart phone. The biosensor is simple and convenient to operate, low in cost and high in accuracy and sensitivity, and can be an auxiliary tool for accurate diagnosis and treatment of the myeloid thyroid carcinoma.