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3133 results about "Polyphenol" patented technology

Polyphenols (/ˌpɒliˈfiːnoʊl, -nɒl/; also known as polyhydroxyphenols) are a structural class of mainly natural, but also synthetic or semisynthetic, organic chemicals characterized by the presence of large multiples of phenol structural units. The number and characteristics of these phenol structures underlie the unique physical, chemical, and biological (metabolic, toxic, therapeutic, etc.) properties of particular members of the class. Examples include tannic acid and ellagitannin. The historically important chemical class of tannins is a subset of the polyphenols.

Calendula double-bacterium fermentation product as well as preparation method and application thereof

The invention discloses a calendula double-bacterium fermentation product as well as a preparation method and application thereof, and relates to the technical field of plant fermentation. The preparation method of the calendula double-bacterium fermentation product disclosed by the invention comprises the following steps: carrying out primary fermentation by using lactobacillus plantarum, then carrying out secondary fermentation by using saccharomyces cerevisiae, and carrying out sterilization and filtration treatment on the calendula fermentation liquid subjected to secondary fermentation, so as to obtain the calendula fermentation liquid. The calendula fermentation liquor is subjected to combined fermentation through lactobacillus plantarum and saccharomyces cerevisiae, and the content of polyphenol and flavone in the calendula double-bacterium fermentation product is remarkably increased. Meanwhile, the calendula double-bacterium fermentation product has the effects of preserving moisture, resisting oxidation, relieving and controlling oil, and has a wide application prospect in the field of cosmetics.
Owner:济南泽润生物科技有限公司

Preparation method and application of interface-modified flame-retardant polypropylene-based bamboo-plastic composite material

The invention discloses a preparation method of an interface-modified flame-retardant polypropylene-based bamboo-plastic composite material. According to the method, a modification solution composed of a polyphenol component and a boron-containing component is adopted, bamboo powder is treated under the normal-temperature stirring condition, and the interface modified bamboo powder is successfully prepared. The mechanism is that polyphenol and a boron-containing component are subjected to a coordination reaction on the surface of bamboo powder, and a reversible borate dynamic covalent bond is constructed. The dynamic bond has a temperature response characteristic: reversible dissociation is realized during high-temperature processing, so that the melt viscosity of a composite system is reduced, and the processing fluidity is improved; the interface bonding force between the bamboo powder and the polypropylene matrix and the mechanical strength of the composite material are remarkably enhanced. In addition, the introduced boron element is used as an efficient flame-retardant component and promotes generation of a compact protective carbon layer during combustion, so that the flame-retardant property of the composite material is comprehensively improved.
Owner:BEIJING UNIV OF CHEM TECH

Probiotic-polyphenol nanoparticle colon-targeted co-delivery system as well as preparation method and application thereof

The invention discloses a probiotic-polyphenol nanoparticle colon-targeted co-delivery system as well as a preparation method and application thereof, and belongs to the field of biological medicines. The FCPs and hyaluronic acid (HA) are combined through non-covalent interaction, so that the hydrogel has colon targeting property and mucosal adhesion at the same time, and delivery of probiotics is facilitated. The hydrogel (HF) based on polysaccharide has good biocompatibility, and can be used for effectively encapsulating the probiotics and the natural products. Then, the PDA-TH NPs and BA are incorporated into the polysaccharide chain network of HF, and finally the BA-HF-PDAT targeted co-delivery system is constructed. The BA (at) HF-PDAT targeted co-delivery system can protect BA from serious gastrointestinal stress, and is jointly assembled with PDT-TH NPs to realize dual slow release of thymol (Thy), so that the treatment effect of BA and Thy is improved, and the BA (at) HF-PDAT targeted co-delivery system contributes to treatment of clostridium difficile infection (CDI).
Owner:NORTHWEST A & F UNIV

Fe monatomic / Pt nanocluster nanoenzyme as well as preparation method and application thereof

The invention relates to the technical field of nano-enzymes, in particular to a Fe monatomic / Pt nano-cluster nano-enzyme as well as a preparation method and application thereof. The invention relates to a preparation method of Fe monatomic / Pt nanocluster nano-enzyme, which comprises the following steps: dispersing graphite phase carbon nitride in water, adding polyphenol and amine, stirring for 10-14 hours, carrying out suction filtration, and drying to obtain a polyphenol amine coated graphite phase carbon nitride precursor; dispersing the graphite-phase carbon nitride precursor in water, adding an iron source and a platinum source, stirring for 10-14 hours, and performing suction filtration, drying, carbonization, acid pickling, centrifugation and drying to obtain the Fe monatomic / Pt nanocluster nanoenzyme. The Fe monatomic / Pt nanocluster nano-enzyme is prepared by the method disclosed by the invention. The invention relates to an application of a Fe monatomic / Pt nanocluster nano-enzyme in pesticide detection. Compared with a single Fe monatomic or Pt nanocluster nano-enzyme, the Fe monatomic / Pt nanocluster nano-enzyme provided by the invention can generate a synergistic effect and has higher catalytic activity.
Owner:SHIHEZI UNIVERSITY

Gene and protein for regulating tobacco polyphenol aroma substances and application of gene and protein

PendingCN120989090APlant peptidesFermentationPhenylpropanoids metabolismGenetics
The invention discloses a gene and a protein for adjusting tobacco polyphenol aroma substances and application of the gene and the protein. The gene is a tobacco NtMYB28 gene, and the CDS sequence of the tobacco NtMYB28 gene is as shown in SEQ ID No. 1. The invention further discloses application of the tobacco NtMYB28 gene in regulating the content of endogenous polyphenol substances in tobacco and regulating and controlling the metabolic pathway of phenylpropane in tobacco. The key gene NtMYB28 capable of simply and effectively adjusting the content of polyphenol substances in tobacco and the metabolic pathway of phenylpropane is found, and the gene can be applied to efficient cultivation of new high-aroma tobacco materials and development and utilization of new high-value functional tobacco germplasm.
Owner:CHINA NATIONAL TOBACCO CORPORATION HUNAN PROVINCIAL CORPORATION

Polyphenol organic ligand, metal polyphenol nano-particles containing polyphenol organic ligand, and preparation method and application of metal polyphenol nano-particles

The invention provides a compound with a structure as shown in a formula (I). The compound can be used as a polyphenol organic ligand to be self-assembled with metal ions to form metal polyphenol nanoparticles. The nano-particles have a bone targeting effect, are safe, effective, stable and uniform, can realize whole-body transfer, can be degraded in a bone pathology microenvironment, have regulation and control effects on bone resorption and bone formation, can cooperatively regulate and control bone balance, and have a great application prospect in the field of bone diseases such as osteoporosis. # imgabs0 #
Owner:EAST CHINA UNIV OF SCI & TECH

Metal-doped carbon quantum dots, preparation thereof and application of metal-doped carbon quantum dots in nano antibacterial agent

The invention discloses a metal-doped carbon quantum dot as well as preparation and application of the metal-doped carbon quantum dot in a nano antibacterial agent, citric acid, urea and tea polyphenol are taken as precursors, metal salt is added, carbon dot synthesis and metal ion doping are synchronously completed in one step through a hydrothermal method, and the metal-doped carbon quantum dot is prepared; the surfaces of the metal-doped carbon quantum dots are negatively charged, and the metal-doped carbon quantum dots have peroxidase-like activity and catalase-like activity at the same time; the metal ions adopt any one of Fe < 3 + >, Cu < 2 + > and Ce < 3 + >; the metal-doped carbon quantum dots are in a sphere-like shape. The metal-doped carbon quantum dots prepared by the preparation method disclosed by the invention have peroxidase-like activity and catalase-like activity at the same time through precise doping of metal ions, and the two activities have a synergistic effect in an oral periodontitis microenvironment, so that a good antibacterial effect is achieved.
Owner:HEFEI UNIV OF TECH

Room temperature formaldehyde sensor material based on catalysis principle and preparation and application thereof

The invention belongs to the technical field of preparation of sensor materials, and particularly relates to a room-temperature formaldehyde sensor material based on a catalytic principle as well as preparation and application of the room-temperature formaldehyde sensor material. The polyphenol is adsorbed on the surface of the semiconductor metal oxide through chelation, then noble metal ions are introduced, and the polyphenol on the surface of the semiconductor metal oxide can capture the noble metal ions and reduce and stabilize the noble metal ions on the surface of the semiconductor metal oxide; the noble metal nanoparticles are anchored on the surfaces of the semiconductor metal oxide nanoparticles, the original morphology of the semiconductor metal oxide is maintained, and the noble metal nanoparticles are loaded on the surfaces of the semiconductor metal oxide nanoparticles. The nano composite material not only has the intrinsic electrical and thermodynamic properties of semiconductor metal oxide, but also combines the catalytic characteristics of noble metal nanoparticles, so that the lower detection limit of formaldehyde is reduced to 3ppb, and the sensitivity of the sensor is remarkably improved. The preparation method of the room-temperature formaldehyde sensing material is simple and suitable for large-scale production, the raw materials are simple and easy to obtain, the cost is low, and the materials are environment-friendly.
Owner:SOUTH CHINA NORMAL UNIV

Ultrasonic-assisted red pomelo polyphenol extraction method and application

The invention provides an ultrasonic-assisted red pomelo polyphenol extraction method and application. The polyphenol component in the red pomelo is extracted through the following steps: firstly, performing activation pretreatment on red pomelo dry powder by adopting a low-temperature plasma device, and destroying a cell wall structure so as to improve the accessibility of combined polyphenol; then cellulase, pectinase, hemicellulase and beta-glucosidase are added into a biodegradable deep eutectic solvent to synergistically hydrolyze the cell wall polysaccharide, and combined polyphenol is released; then applying pulse type ultrasonic wave to assist extraction under a low-temperature condition, so that polyphenol is fully dissolved out and enters the eutectic solvent; and finally, carrying out solid-liquid separation to obtain the red pomelo polyphenol extract. Compared with a conventional heat extraction method, the method has the advantages that the extraction rate of the polyphenol of the red pomelo is remarkably increased at a lower temperature, the degradation of the polyphenol is effectively avoided, and the content of the total polyphenol and the antioxidant activity are increased; the method is green and environment-friendly, and can be applied to the health industry as an antioxidant.
Owner:ZAOFENGDA HEALTH TECHNOLOGY CHONGQING CO LTD

Metal polyphenol network coated self-assembled nano-drug as well as preparation method and application thereof

The invention provides a metal polyphenol network coated self-assembled nano-drug as well as a preparation method and application thereof, and belongs to the technical field of nano-drugs. The self-assembled nano-drug provided by the invention is of an organic-inorganic hybrid core-shell nano-structure; the core of the organic-inorganic hybrid core-shell nano structure is BC NPs; the BC NPs is formed by self-assembly of BBR (Boron Butadiene Rubber) and Cur (Carbon); a shell layer of the organic-inorganic hybrid core-shell nanostructure is a dynamic cross-linked network formed by self-assembly of metal ions and polyphenol through coordination. Metal ions and polyphenol are self-assembled through coordination to form a dynamic cross-linked network, and the dynamic cross-linked network coats the outer layer of the BC NPs nano-particles, so that the BC NPs nano-particles have good biocompatibility and biological safety; and the self-assembled nano-drug shows an obviously enhanced antibacterial effect under the combined treatment of NIR and H2O2.
Owner:NORTHEAST FORESTRY UNIV

Whitening and freckle-removing composition containing composite plant extract and preparation method of whitening and freckle-removing composition

The invention relates to a whitening and freckle-removing composition containing a composite plant extract and a preparation method of the whitening and freckle-removing composition, and belongs to the technical field of cosmetics. The composition disclosed by the invention is prepared from the following raw materials in parts by weight: 5 to 8 parts of pineapple leaf nano cellulose, 10 to 16 parts of modified starch, 10 to 15 parts of longan seed extract, 6 to 10 parts of mulberry bark extract, 5 to 8 parts of nicotinamide and 8 to 10 parts of hyaluronic acid. The pineapple leaf nanocellulose contains flavonoid and phenolic compounds with double-bond, conjugated double-bond and triple-bond structures, and modified starch is used as a filler to form a film on the surface of skin, so that an anti-ultraviolet protection wall is formed; the betaine-malate ionic liquid is added into the longan seeds, so that extraction of polyphenol in the longan seeds is improved, the longan seeds have acid-base buffering capacity, an auxiliary does not need to be added to adjust the pH value, the components of the prepared composition interact, and the whitening and freckle removing effects are achieved from multiple aspects of ultraviolet resistance, oxidation resistance, inflammation resistance and skin metabolism improvement.
Owner:GUANGZHOU QIAOZIYAN COSMETICS CO LTD

Casein-tea polysaccharide-polyphenol composite nanoparticles and preparation method thereof

The invention relates to the technical field of food processing, and discloses casein-tea polysaccharide-polyphenol composite nanoparticles and a preparation method of the casein-tea polysaccharide-polyphenol composite nanoparticles, and the preparation method comprises the following steps: mixing large yellow tea polysaccharide with a casein solution to obtain a CS / TPS mixed solution; performing glycosylation modification on casein in the CS / TPS mixed solution by adopting a Maillard reaction to prepare a casein-polysaccharide copolymer solution; the preparation method comprises the following steps: mixing a plurality of catechins, dissolving the catechins in ultrapure water to obtain a mixture stock solution, mixing the mixture stock solution and a casein-polysaccharide copolymer solution according to a volume ratio of 1: 16, stirring for 1 hour for self-assembly, pre-freezing the stirred solution at-80 DEG C, and freeze-drying for 48 hours to obtain CS-TPS-MIX nano-composite powder. According to the invention, a polyphenol delivery system with a dual antioxidant synergistic mechanism is constructed through a Maillard reaction mediated nano-composite technology, and the system is stable in structure, so that the release of polyphenol is more controllable.
Owner:ANHUI AGRICULTURAL UNIVERSITY +1

Zinc polyphenol complex suppository as well as preparation method and application thereof

The invention discloses a zinc polyphenol complex suppository as well as a preparation method and application thereof. The preparation process mainly comprises two steps as follows: a, preparation of EGCG-Zn metal polyphenol complex nanoparticles; and b, preparing the nano complex suppository. The method is simple in process, green, environment-friendly and suitable for large-scale preparation. The prepared EGCG-Zn nanoparticles are uniform in particle size and good in stability, and have good antioxidant, anti-inflammatory and tissue repair activity based on a complex network structure formed by self-assembly of EGCG and zinc ions. The nano-particles are firstly treated by adopting a drug pretreatment carrier and then loaded in a suppository matrix to construct a rectal administration type nano-suppository, so that targeted and continuous local drug effect release can be realized. In intervention of radioactive intestinal injury, the suppository not only can relieve oxidative stress and inflammatory response, but also can promote regeneration and repair of intestinal mucosa, and has good treatment potential and clinical application prospect.
Owner:ZHEJIANG CANCER HOSPITAL

Caragana sinica Kangpu tea as well as preparation method and application of caragana sinica Kangpu tea

The invention relates to the technical field of food processing, and in particular relates to a sparrow chensinensis Kangpu tea as well as a preparation method and application thereof, the preparation method comprises the following steps: extracting sparrow chensinensis and water according to a ratio of 1: (50-100) at 70-90 DEG C for 40-60 minutes, filtering, and adding cane sugar to obtain a fermentation substrate; the preparation method comprises the following steps: preparing seed liquid, namely activating casei paracasei, phytobacterium plantarum, acetobacter pasteurianus and kluyveromyces marxianus into seed liquid, inoculating the seed liquid into a substrate according to the inoculum size of 0.5-1.5%, fermenting for 5-10 days under the conditions that the temperature is 37 DEG C and the pressure is 0.03-0.05 MPa, and sterilizing (optionally drying) to obtain the parochetus ocellatus Kangpu tea. The preparation method of the parochetus ocellatus Kangpu tea is accurate and controllable in fermentation, safe and stable; the product retains the nutrition of the raw materials, the bioavailability of polyphenol after fermentation is improved, the antioxidant activity is enhanced, the flavor is soft, caffeine is avoided, and the product is suitable for a wide range of people and can be used for preparing antioxidant functional food.
Owner:QINGDAO HUIBAICUI BIOTECHNOLOGY CO LTD

Starch-based full-biodegradable mulching film capable of being quickly degraded and preparation method of starch-based full-biodegradable mulching film

The invention discloses a starch-based full-biodegradable mulching film capable of being rapidly degraded and a preparation method of the starch-based full-biodegradable mulching film, and belongs to the technical field of degradable materials.The preparation method comprises the steps of tea polyphenol calcium salt preparation, filler preparation, thermal plasticization and film preparation. The preparation of the filler comprises the following steps: adding silicon dioxide into a polyacrylic acid aqueous solution, stirring and centrifuging at room temperature, taking a precipitate, adding the precipitate into a polyvinylpyrrolidone aqueous solution, adjusting the pH value to 3-3.5, stirring and centrifuging at room temperature, taking the precipitate, adding the precipitate into the polyacrylic acid aqueous solution, adjusting the pH value to 3-3.5, stirring and centrifuging at room temperature, taking the precipitate, and freeze-drying to obtain the filler. The starch-based full-biodegradable mulching film prepared by the preparation method disclosed by the invention is good in processability, waterproofness and heat resistance and high in mechanical strength, the problem of phase separation does not occur in preparation, the problem of plasticizer precipitation does not easily occur in long-term use, and rapid degradation can be realized.
Owner:SHANDONG SHOUGUANG JUNENG GOLDEN CORN CO LTD +1

Preparation method of bacteriostatic and antioxidant zein / hyaluronic acid degradable preservative film

A preparation method of a bacteriostatic and antioxidant zein / hyaluronic acid degradable preservative film relates to the field of foods.The method comprises the steps that a zein-hyaluronic acid solution and a citrus polyphenol solution are mixed, distilled water is dropwise added, vacuum concentration is performed, the mixture is mixed with a laminarin solution, auxiliary materials are added, uniform mixing, bubble removing and film preparing are performed, and the preservative film is obtained. After drying, obtaining a zein-HA film of laminarin and citrus polyphenol; or mixing the zein-hyaluronic acid solution with the moringa oleifera leaf extract powder, dropwise adding distilled water, concentrating under reduced pressure, mixing with the laminarin solution, adding the sodium alginate solution and auxiliary materials, defoaming, pouring to form a film, and drying to obtain the zein-HA film of the laminarin and the moringa oleifera leaf extract. The synergistic effect among the substances of the protein film can effectively improve the fresh-keeping effect of the composite film, and the release property of the composite film can further improve the fresh-keeping effect on fresh-cut food.
Owner:SUIHUA UNIV

A composite fiber containing nano-natural tea fiber and its preparation method and application

The present invention belongs to the technical field of fiber materials, and relates to a composite fiber containing nano natural tea fibers, and a preparation method and application thereof. The raw materials for preparing the composite fiber include nano natural tea fibers and basic fiber pulp, and the nano natural tea fibers are mate nano fiber microemulsions. The present invention integrates nanotechnology into the preparation of natural tea fibers, and adopts a microemulsion method to simultaneously and evenly disperse a variety of effective ingredients in tea in the mate nano fiber microemulsion, so that the multifunctionality of the fabric can be effectively exerted; the microemulsion system has high uniformity and long-term stability, and during the spinning process, the nano tea fibers can be highly dispersed in the spinning solution without the need for additional surfactants, and the effect of the functional fabric finally obtained can be long-lasting. In addition, mate tea is rich in tea polyphenols and unique yerba mate alkaloids, which can further improve the comprehensive performance of the composite fiber.
Owner:ZHEJIANG JUPITER EXPERIMENTAL TECH CO LTD

Aspergillus niger strain, culture method and application thereof

The application discloses an Aspergillus niger strain and a culture method and application thereof, the Aspergillus niger strain is preserved in China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 20241727. The fermented tea product obtained by fermenting tea leaves or tea leaf extracts by using the Aspergillus niger strain CCTCC NO: M 20241727 has prominent sweet and floral fragrance, and the astringency is obviously reduced; the contents of tea polyphenols, free amino acids and flavones are higher than those of a fermented tea product of an existing Aspergillus niger strain; the antioxidant activity is enhanced; the tea soup color is orange red and bright; and the color, fragrance and taste qualities are all superior to those of the fermented tea product of the existing Aspergillus niger strain.
Owner:ANHUI AGRICULTURAL UNIVERSITY

Preparation of dual cross-linked ZEIN-carboxymethyl chitosan nanoparticles for improving thermal stability of polyphenol

Disclosed is preparation of dual cross-linked zein-carboxymethyl chitosan nanoparticles for improving the thermal stability of polyphenol. After covalently cross-linked zein, tannic acid is used to prepare tannic acid cross-linked zein-carboxymethyl chitosan nanoparticles loaded with quercetin, Ca2+ is then added to increase a degree of crosslinking between the tannic acid and the carboxymethyl chitosan, as well as between molecules of the carboxymethyl chitosan in the zein nanoparticles to make the structure tighter, such that structural stability of the nanoparticles can be maintained during the thermal processing after the nanoparticles are formed, the quercetin encapsulated inside is protected well, and a retention rate of quercetin during the thermal processing is improved. The method provided in the present disclosure is simple, green, pollution-free and low energy consumption, and the prepared nanoparticles can improve the thermal stability of quercetin, and can be used as a natural additive for thermal processing of food.
Owner:JIANGNAN UNIV

Functional probiotic composition and application thereof

The invention discloses a functional probiotic composition and application thereof, and relates to the technical field of microbial engineering. Bifidobacterium longum, lactobacillus acidophilus and enterococcus faecalis are combined to serve as a microbial agent, the microbial agent and active substances of the tea leaves form a composition, then the composition is combined with prebiotics, it is ensured that viable bacteria directly reach the intestinal tract through a microencapsulation technology, and the effect of improving the immune function is achieved; tea polyphenol in the active substances of the tea leaves can serve as a carbon source of prebiotics to stimulate proliferation of the bifidobacterium longum and the lactobacillus acidophilus, so that the acid resistance and intestinal colonization capacity of the microbial inoculum are enhanced, and meanwhile, theanine in the active substances of the tea leaves, the bifidobacterium longum and the lactobacillus acidophilus synergistically promote secretion of gamma-aminobutyric acid, so that the effect of improving the intestinal colonization is achieved. And the tea polyphenol can inhibit the large intestine rod from adhering to the intestinal mucosa, and the probiotic agent secretes antibacterial peptide, so that the integrity of the intestinal barrier is maintained together.
Owner:JIANGSU BEIXING BIOTECHNOLOGY CO LTD

Preparation method of self-healing polyurethane composite material with heat conduction and electromagnetic shielding functions

The invention discloses a preparation method of a heat conduction and electromagnetic shielding self-healing polyurethane composite material, which comprises the following steps: modifying nano cellulose CNF (denoted as CNF-coated PPA) by using polyphenol amine PPA, and depositing silver nanoparticles on the surface of the CNF-coated PPA in situ to obtain a deposited material; the preparation method comprises the following steps: preparing a polyamide epichlorohydrin PAE solution, modifying graphene nanosheets GNP by using the PAE solution, and recording the modified graphene nanosheets GNP as PAE-GNP suspension liquid; cNF (at) PPA (at) Ag is dispersed into the PAE-GNP suspension liquid, and the CNF (at) PPA (at) Ag suspension liquid is marked as CNF-GNP suspension liquid; and preparing waterborne polyurethane WPU, dispersing the CNF-GNP suspension into the WPU, and carrying out vacuum filtration, drying and hot pressing on the mixed solution to obtain the polyurethane composite material. The method is simple in preparation process, mild in reaction condition and stable in product quality, and the polyurethane composite material prepared according to the method has excellent heat conduction, electromagnetic shielding and self-healing performance.
Owner:BEIJING UNIV OF CHEM TECH

Stainless steel material for food-grade straw and preparation process of stainless steel material

The invention discloses a stainless steel material for a food-grade straw and a preparation process of the stainless steel material, and relates to the technical field of stainless steel material plating. The silver coating and the antibacterial coating are arranged on the surface of the stainless steel material, and the stainless steel material has good wear resistance and antibacterial performance through the action of the double protective layers. Sulfonated polyphenylene sulfide is added into a silver plating solution, a plating layer is formed after electroplating, the surface of a stainless steel material is not prone to being scratched, the wear resistance of stainless steel is improved, quaternary ammonium salt modified tea polyphenol-nano-silver composite particles are added into the antibacterial coating, and through the synergistic antibacterial effect of quaternary ammonium salt, tea polyphenol and nano-silver, the wear resistance of the stainless steel material is improved. The broad-spectrum antibacterial property is realized, and the efficient antibacterial effect is achieved.
Owner:JIANGSU YONGJIN METAL TECHNOLOGY CO LTD

Acid-responsive nanoprobe as well as preparation and anti-tumor application thereof

The invention discloses an acid responsive nanoprobe as well as preparation and anti-tumor application thereof. The nanoprobe has a core-shell structure, takes a nanoparticle self-assembled by a polycation aggregation-induced emission (AIE) photosensitizer and functional nucleic acid as a core, and takes a hyaluronic acid modified metal polyphenol network as a shell. The nanoprobe utilizes the acid responsiveness and broad-spectrum absorption performance of the metal polyphenol network and the diagnosis and treatment advantages of the polycation AIE photosensitizer to realize the acid responsiveness'switch 'controllable diagnosis and treatment of the tumor nanoprobe. In a neutral environment, the fluorescence is weak, the generation of ROS is less, and the background noise signal of the nanoprobe and the toxicity of non-targeted tissues are reduced; in an acid environment, fluorescence is enhanced, the ROS yield is improved, and the treatment efficiency and the curative effect monitoring accuracy are improved. The nano diagnosis and treatment probe is ingenious in design and simple to prepare, and can realize PDT and gene therapy synergistic anti-tumor, in-situ real-time report of early tumor treatment effect and assistance in precise cancer treatment.
Owner:ZHENGZHOU UNIV

Method for efficiently extracting tea polyphenol and tea polysaccharide and application

The invention provides a method for efficiently extracting tea polyphenol and tea polysaccharide and application, and belongs to the technical field of plant extraction.The extraction method comprises the following steps that tea leaves are pre-cooled and rolled and cut to obtain pretreated tea leaves, then the pretreated tea leaves are added into water to be mixed, biological enzyme is added for ultrasonic enzymolysis, filtering is conducted, and filtrate and tea residues are obtained; adding tea residues into water, mixing, adding an auxiliary agent, and carrying out low-temperature plasma treatment and filtration to obtain a filtrate; combining the filtrates, concentrating, precipitating, centrifuging, and collecting precipitate and supernate; washing and drying the precipitate to obtain a tea polysaccharide extract; and concentrating, extracting, adsorbing, eluting, re-concentrating and drying the supernate to obtain the tea polyphenol extract. The extraction method disclosed by the invention can be used for efficiently extracting the tea polyphenol and the tea polysaccharide in the tea leaves, the product yield and purity are high, and the tea polyphenol and the tea polysaccharide can be used for preparing health-care products for relieving diabetes and polyuria.
Owner:HENAN AGRICULTURAL UNIVERSITY

Ostrich meat preservative and preservation method

The invention belongs to the field of food processing, and particularly relates to an ostrich meat preservative and a preservation method. The ostrich meat preservative provided by the invention is prepared by matching and mixing the chitosan, the nisin and the tea polyphenol according to a specific proportion, so that the refrigeration refreshing time of the ostrich meat treated by the preservative can be effectively prolonged, the ostrich meat can maintain a relatively high L * value and a * value within 16 days of storage, the deterioration of meat color is delayed, the water-retaining property is remarkably improved, and the quality of the ostrich meat is improved. The content of thiobarbituric acid reactants and volatile basic nitrogen is obviously reduced, and fat oxidation and protein degradation are inhibited; the total number of bacterial colonies and the number of microorganisms such as coliform bacteria, pseudomonas, mould and saccharomycetes are obviously reduced. The growth and reproduction of putrefying bacteria can be effectively inhibited, and the cold fresh shelf life is prolonged.
Owner:PINGDINGSHAN SHUNHE AGRI DEV CO LTD

Water-based environment-friendly mutual exclusion printing ink

The invention relates to the field of water-based environment-friendly ink, and discloses water-based environment-friendly mutual exclusion ink which comprises the following components: water-based polyurethane-acrylic hybrid resin; a nanocellulose crystal; modifying the plant polyphenol pigment; and gamma-valerolactone; a polyglycerol ester surfactant; a pH response type microcapsule; the invention further provides a preparation method of the water-based environment-friendly mutual-exclusion ink. The preparation method comprises the following steps: S1, preparing the nanocellulose crystal; s2, plant polyphenol pigment modification; s3, preparing a pH response type microcapsule; s4, synthesizing waterborne polyurethane-acrylic acid hybrid resin; and S5, constructing an ink system. According to the invention, a dynamic crosslinking technology of the waterborne polyurethane-acrylic hybrid resin is adopted, so that the flexibility and durability of the ink after coating are remarkably improved, the ink has better recovery capability and stronger mechanical properties, breakage or falling of the ink under stress is avoided, and the service life of the ink is prolonged.
Owner:FU YANG BAO ZHUANG CAI LIAO SU ZHOU YOU XIAN GONG SI

Fresh-keeping composite solution sprayed before picking of fruits in cold-chain logistics transportation and preparation method of fresh-keeping composite solution

The invention provides a fresh-keeping composite solution sprayed before picking fruits in cold-chain logistics transportation and a preparation method of the fresh-keeping composite solution, and relates to the field of fruit fresh keeping. The fresh-keeping composite solution is prepared from the following raw materials in parts by weight: 2.8 to 3.5 parts of schizochytrium limacinum powder, 2.3 to 2.8 parts of salvia officinalis extract, 1.8 to 2.2 parts of brown algae extract, 1.2 to 1.8 parts of banana peel polysaccharide, 0.8 to 1.2 parts of sodium carboxymethyl cellulose, 0.8 to 1.2 parts of tea polyphenol, 0.8 to 1.2 parts of beta-cyclodextrin, 0.8 to 1.2 parts of sodium alginate, 0.8 to 1.2 parts of calcium chloride, 0.4 to 0.6 part of olive oil, 0.1 to 1 part of malic acid and 80 to 90 parts of water. The composite fresh-keeping solution is developed for cold-chain logistics transportation of fruits and is applied before fruit picking, the synergistic effect of multiple natural components is utilized, sterilization and oxidation resistance can be achieved, the growth of microorganisms can be effectively inhibited, the respiration rate of the fruits is reduced, the moisture of the fruits is kept, and the optimal fresh-keeping effect is achieved. The fruit preservative is sprayed before the fruits are picked, so that decay and quality reduction of the fruits in the cold-chain logistics transportation process can be effectively reduced.
Owner:HUNAN INST OF APPLIED TECH

Persistent antibacterial composite tooth socket for drug loading and preparation method thereof

The invention relates to the field of oral cavities, and particularly discloses a lasting antibacterial type composite tooth socket for medicine carrying and a preparation method thereof.The lasting antibacterial type composite tooth socket comprises an adsorption layer and an antibacterial membrane layer, the adsorption layer is used for adsorbing oral cavity treatment liquid medicine, and the antibacterial membrane layer comprises a nano-silver antibacterial layer and a chitosan antibacterial layer; the preparation method comprises the following steps: mixing a tea polyphenol-polylactic acid composite solution, a nano-silver-carboxylation modified cellulose compound and a polyvinyl alcohol solution, and carrying out electrostatic spinning to prepare a nano-silver antibacterial fiber membrane, so as to form the nano-silver antibacterial layer; mixing chitosan with hot water, adding cinnamyl aldehyde, glycerol and boric acid, stirring to obtain a mixed solution, coating one side of the nano-silver antibacterial layer with the mixed solution, and curing to form a chitosan antibacterial layer; the adsorption layer is attached to the side, away from the chitosan antibacterial layer, of the nano-silver antibacterial layer, and then the lasting antibacterial type composite tooth socket for carrying the medicine is prepared through hot-pressing compounding. The drug-loaded composite tooth socket has the characteristic of further improving the antibacterial property and the antibacterial durability of the drug-loaded composite tooth socket.
Owner:XI'AN UNIVERSITY OF ARCHITECTURE AND TECHNOLOGY

Preparation method and application of mulberry leaf extract with high stability and high activity in protein food system

PendingCN121369688AMilk preparationFood shapingBiotechnologyDeoxynojirimycine
The invention discloses a preparation method and application of a mulberry leaf extract with high stability and high activity in a protein food system, and belongs to the field of food processing and nutrition and health. The mulberry leaf extract is prepared by taking mulberry leaves as a raw material through steam explosion and ball milling pretreatment, compound enzyme directional enzymolysis, ultrasonic-assisted extraction, protein-induced sedimentation combined with ultrafiltration membrane selective impurity removal, compound stabilization treatment and drying. The obtained extract is rich in 1-deoxynojirimycin (DNJ) and mulberry leaf polysaccharide, high-polymerization-degree polyphenol is remarkably removed, and high clarity and heat stability are achieved. The DNJ retention rate gt is obtained after the milk is stored at 37 DEG C for 7 days when the milk protein is applied to a milk system; and therefore, the product prepared by the method is obviously superior to the product prepared by the prior art. The extract is pure in flavor and high in biological activity, and can be widely applied to the field of healthy foods such as dairy products and protein beverages.
Owner:SUZHOU LANGBANG NUTRITION TECH CO LTD

Metal-polyphenol network modified coconut protein composite particle as well as preparation method and application thereof

The invention belongs to the technical field of emulsion materials, and particularly relates to metal-polyphenol network modified coconut protein composite particles as well as a preparation method and application thereof. The preparation method comprises the following steps: preparing a coconut protein-pectin compound by taking coconut protein and pectin as raw materials, adding a tannic acid solution into the coconut protein-pectin compound, mixing, adding a Fe < 3 + > solution, and mixing to obtain metal-polyphenol network modified coconut protein composite particles; according to the preparation method, tannic acid and the coconut protein-pectin compound are subjected to non-covalent interaction, Fe < 3 + > and phenolic hydroxyl groups on the tannic acid are subjected to coordination reaction, a metal-polyphenol network is formed through cross-linking of Fe-O coordination bonds, and a compact modification layer is constructed on the surface of the coconut protein-pectin compound, so that on one hand, waste coconut protein resources are utilized; on the other hand, the problem that composite particles prepared from pectin and coconut protein are prone to depolymerization is solved, the structural stability is improved, and meanwhile iron and polyphenol are supplemented.
Owner:HAINAN UNIV