The invention relates to a preparation method of seawater rice brown rice enzyme powder. The preparation method comprises the following steps: selecting high quality seawater rice, evenly mixing ampelopsis grmsedntarac, polygonatum rhizome, wolfberry, raspberry, water, and brown sugar water to obtain a culture solution; inoculating composite probiotic fermenting liquid containing brewer's yeast, candida utilis, and lactobacillus helveticus to the culture solution to carry out fermentation culture so as to obtain a domesticating solution, wherein the inoculation amount is 1 to 5%; soaking high quality seawater rice brown rice into the domesticating solution for 15 to 24 hours; then transferring the sweater rice brown rice to a germinator, which has the functions of automatic temperature control, atomizing and wetting, and ventilation, to promote germination, then rinsing geminated seawater rice brown rice by water; drying until water content of dried brown rice is 10 to 15%; primarily grinding the brown rice, adding chia seeds and jujube, fully stirring, and carrying out ultrafine grinding to obtain the seawater rice brown rice enzyme powder. Seawater rice brown rice is domesticated, cultured, and geminated in a domesticating solution, the palatability and solubility are good, the enzyme powder can be well digested and absorbed by human body, and has the advantages of user-friendliness, unique taste, rich nutrients, and long shelf life, and the technology is simple and reasonable.