27 results about "Chinese licorice" patented technology

The invention discloses an essence composition for promoting eyelash growth and a preparation method thereof.The essence composition comprises a phase A, a phase B, a phase C, a phase D and a phase E. The phase B comprises natural active extracts. The natural active extract comprises butyrospermum parkii butter, a matricaria chamomilla leaf extract, glycyrrhiza glabra, a centella asiatica extract, a rosemary leaf extract, tocopherol, a scutellaria baicalensis root extract, a tea leaf extract and a polygonum cuspidatum root extract in a mass ratio of (0.488985): (0.005): (0.0025): (0.0025): (0.0005): (0.0005): (0.000005): (0.000005): (0.000005). On the premise that safety and mildness are guaranteed, the eyelash density and length are remarkably improved through low-dosage active ingredients, and the safe and efficient requirements of daily eyelash nursing can be met.

The invention relates to a light-triggered slow-release sterilization type perfume composition and a preparation method thereof, and belongs to the technical field of perfume. The light-triggered slow-release bactericidal perfume composition comprises the following components in percentage by mass: 0.1-0.3 wt% of fullerene subjected to surface modification, the fullerene is subjected to surface modification treatment through a surface modifier in advance, and the surface modifier is selected from at least one of polyvinylpyrrolidone and hydroxypropyl-beta-cyclodextrin; the toothpaste comprises the following components in percentage by weight: 2.5-3.5% of glycyrrhiza glabra extract, 10-15% of essence and 0.1-0.5% of a pH regulator, and is used for regulating the pH of a system to 5.5-6.5; the solvent comprises a main volatile solvent, a polar solvent and water. The invention further discloses a preparation method of the perfume. The fullerene and the glycyrrhiza glabra extract are applied to a perfume formula, so that the perfume is endowed with a sterilization function, and the requirements of modern consumers on multifunctional personal care products are met.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a method for simultaneously extracting and purifying glabridin, glycyrrhizic acid and isoliquiritigenin. The method comprises the following steps: (1) adding ethanol into glycyrrhiza glabra, and extracting to obtain an extracting solution; (2) extracting the extracting solution with ethyl acetate to obtain an organic phase and a water phase; and (3) purifying the organic phase by using a rapid preparative liquid chromatograph, carrying out gradient elution by using 30%-70% of ethyl acetate-cyclohexane as a mobile phase, and collecting the eluent, thereby obtaining the glabridin. (4) carrying out acidification and centrifugal precipitation on the water phase to obtain a glycyrrhizic acid crude product and a supernatant, adding absolute ethyl alcohol into the glycyrrhizic acid crude product, and carrying out ultrasonic extraction and centrifugation to obtain a glycyrrhizic acid ethanol solution; and (5) extracting and purifying the supernate to obtain the isoliquiritigenin.

The invention belongs to the technical field of cosmetics, and particularly relates to an oil-soluble composite plant extract as well as a preparation method and application thereof. The oil-soluble composite plant extract is prepared from the following components in percentage by mass: 0.8 to 1.2 percent of chamomilla recutita flower extract, 0.4 to 0.8 percent of glycyrrhiza glabra root extract, 0.4 to 1.0 percent of peony extract, 0.3 to 0.7 percent of herba centellae extract, 0.08 to 0.12 percent of rosemary leaf extract, 0.08 to 0.12 percent of tocopherol, 0.0010 to 0.0014 percent of tea leaf extract, 0.0010 to 0.0016 percent of rhizoma polygoni cuspidati root extract, 0.0010 to 0.0014 percent of radix scutellariae root extract and the balance of butyrospermum parkii butter. By optimizing the preparation method of the peony extract, the content of total polyphenols in the peony extract is increased. The oil-soluble composite plant extract is applied to skin care products and has the effects of improving skin elasticity and resisting aging.

The invention belongs to the field of cosmetics and health care products, and provides a whitening compound based on cattle spleen peptide and a preparation method and application thereof, and the whitening compound comprises cattle spleen peptide and one or more components selected from glycyrrhiza glabra root extract, nicotinamide, ferulic acid and vitamin C. The whitening compound realizes whitening through the synergistic effect of three paths of synthesis inhibition, transport blocking and oxidation reduction, can be prepared into freeze-dried powder, hydrogel films or oral capsules, realizes high-value utilization of cattle spleen resources, and breaks through the synergistic problem of'safety-efficacy-stability 'of whitening components.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a method for simultaneously extracting and purifying glabridin, glycyrrhizic acid and isoliquiritigenin by a column chromatography extraction method. The method comprises the following steps: adding an ethanol solution into glycyrrhiza glabra, extracting by adopting a column chromatography extraction method, extracting an extracting solution by using dichloroethane, enabling an organic phase to pass through a silica gel column, and crystallizing an eluent to obtain glabridin. Acidifying and centrifuging the extracted water phase, and dissolving the precipitate with acetone to obtain glycyrrhizic acid; and extracting and purifying the filtrate to obtain the isoliquiritigenin. The invention provides a simple and efficient new extraction technology which is low in energy consumption, small in solvent dosage and high in extraction rate compared with traditional ultrasonic extraction and the like, and aims to extract glycyrrhizic acid and glabridin in glycyrrhiza glabra at the same time, separate glycyrrhizic acid and glabridin, separate isoliquiritigenin from the remaining part through simple conversion, and improve the purity of glycyrrhizic acid and glabridin in glycyrrhiza glabra. The comprehensive development and utilization of the glycyrrhiza glabra are achieved.

The invention relates to the field of extraction, separation and purification of natural products, in particular to a method for purifying glabridin from glycyrrhiza glabra waste residues. According to the method, the glycyrrhiza glabra waste residues are taken as raw materials, and efficient purification is realized through a three-step core process: firstly, heating reflux extraction is performed by adopting a specific small-polarity organic solvent; secondly, carrying out primary purification by utilizing polyamide resin column chromatography; finally, specific ultra-pure microsphere polymer adsorption resin or two types of C18 reverse-phase silica gel fillers are innovatively selected for refining chromatography. Through optimized combination of a filler system, the key problems of low purification efficiency, high solvent consumption, difficulty in large-scale production and the like in a traditional process are solved, the process flow is simple and stable, the solvent can be recycled, a high-purity product with the glabridin content not lower than 92% can be efficiently prepared from the waste residues, high-value utilization of waste resources is achieved, and the method is suitable for industrial production. And the method has remarkable economic and environmental benefits.

This invention provides a traditional Chinese medicine (TCM) whitening and freckle-removing composition and its application in the preparation of skincare products. The TCM whitening and freckle-removing composition comprises the following raw material components by weight percentage: Dendrobium nobile extract (principal ingredient) 0.1-5.0%; Astragalus membranaceus extract (assistant ingredient) 0.5-8.0%; Papaya extract 0.1-3.0%; Polygonum multiflorum extract 0.1-3.0%; Ginseng extract 0.05-2.0%; Ligusticum chuanxiong extract 0.05-2.0%; oil-soluble licorice extract (Glycyrrhiza glabra, containing glycyrrhizin) 0.01-1.0%; Carthamus tinctorius (Saffron) extract 0.01-0.5%; and Angelica sinensis extract 0.05-1.0%. Based on TCM principles, this invention uses authentic Chinese medicinal materials and modern extraction and formulation techniques to create various formulations of skincare products that offer both external whitening effects and gentle repair, thus solving the technical problem of long-term, safe, and effective whitening and freckle-removing treatment.

The invention provides a soothing and repairing composition as well as a preparation method and application thereof. The soothing and repairing composition is prepared from ceramide, phytosterol, superoxide dismutase, cyclodextrin, a plant extract and water, the plant extract comprises any one or a combination of at least two of a glycyrrhiza inflata root extract, a glycyrrhiza glabra extract and a gynura divaricata root juice. The ceramide, the phytosterol, the superoxide dismutase and the plant extract in the composition are matched for use, so that the composition has excellent repairing, relieving, anti-inflammatory and anti-oxidation effects, in addition, the stability and the transdermal property of the active ingredients can be improved by using the cyclodextrin in the composition, and the composition can be used for repairing and relieving inflammation and resisting oxidation. And the skin feeling of the product can be further adjusted.

The present invention relates generally to methods and compositions useful for concealing skin imperfections. The method can include applying a topical composition to facial skin, for example skin under the eye. The composition can include Glycyrrhiza glabra root extract, disteardimonium hectorite, trisiloxane, triethyl citrate, cetyl dimethicone, and cetyl PEG / PPG-10 / 1 dimethicone.

The invention belongs to the field of separation and purification, and discloses an extraction method and application of high-purity glabridin, and the extraction method specifically comprises the following steps: a glycyrrhiza glabra raw material and a pH response type DES reagent are mixed, stirred and extracted for 1-2 hours, centrifugation is carried out, a supernatant is collected, and the pH response type DES reagent is composed of hydrogen bond receptor choline chloride and hydrogen bond donor malonic acid; and adding an alkali solution into the supernate to adjust the pH value to 7.0-8.0 for phase separation, separating into an upper-layer solution phase and a lower-layer precipitation phase, collecting the lower-layer precipitation phase, centrifuging, washing and drying to obtain the glabridin. According to the invention, the integration of extraction and primary separation is realized, the extraction and primary enrichment are combined into one in the process of'alkali addition, namely precipitation ', and meanwhile, the DES component can be almost quantitatively recovered, so that the production cost and the environmental burden are greatly reduced, the purity of the obtained product is higher, and the load of the subsequent refining process is reduced.

The invention relates to a method for preparing total flavonoids rich in glabridin from glycyrrhiza glabra residues at low temperature. The method comprises the following specific steps: adding an ethanol-water solution into glycyrrhiza glabra residues for extraction, concentrating an extracting solution, and sequentially carrying out resin enrichment, decoloration, purification, concentration and low-temperature drying on a concentrated solution to obtain the high-purity total flavonoids (the content of the total flavonoids is greater than or equal to 92%, and the content of glabridin is greater than or equal to 40%). The process flow provided by the invention is simple, convenient, controllable, green and environment-friendly; only ethanol is used as an organic solvent in the extraction and purification process, the solvent can be recycled, meanwhile, a separation material can be repeatedly used, and the production cost of a unit product is remarkably reduced; according to the process, the product transfer rate is high, and large-scale preparation and industrial production are stably and efficiently realized.

This application provides a natural eutectic solvent for extracting glycyrrhizin, the preparation method of which includes: firstly, dissolving nicotinamide in 1,2-propanediol, then adding an appropriate amount of deionized water and heating and stirring to form a transparent and homogeneous liquid without crystal precipitation at room temperature; wherein the molar ratio of nicotinamide to 1,2-propanediol is 1:(6~12), and the mass percentage of deionized water is 20%~50%. A method for preparing licorice root extract is also provided, comprising: ultrasonically extracting licorice root powder with the above-mentioned natural eutectic solvent, then separating the extract and collecting the supernatant. This natural eutectic solvent is simple to prepare, low in cost, low in toxicity, regenerable, and biodegradable. Using this natural eutectic solvent in conjunction with a suitable process to extract flavonoids, glycyrrhizin, and other active ingredients from licorice root yields high extraction rates, low cost, and the extract exhibits good safety, antioxidant, and whitening effects.

The invention relates to the technical field of cosmetics, and particularly discloses a composition with anti-aging and brightening effects as well as a preparation process and application thereof. The composition with the effects of resisting initial aging and brightening is prepared from the following components in percentage by weight: 1 to 5 percent of glycyrrhiza glabra root extract, 10 to 20 percent of silybum marianum extract, 0.005 to 0.01 percent of palmitoyl pentapeptide-4, 0.0005 to 0.001 percent of arginine / lysine polypeptide, 0 to 1 percent of sargassum elongatum extract, 0 to 1 percent of olive leaf extract, 0 to 1 percent of diglucosyl gallic acid, 0 to 0.5 percent of dendrobium officinale stem extract and the balance of water. The glycyrrhiza glabra root extract is an anti-saccharification glycyrrhiza glabra root extract, and the anti-saccharification glycyrrhiza glabra root extract is prepared by carrying out directional hydrolysis treatment on a glycyrrhiza glabra root extract. According to the present invention, the collagen regeneration can be effectively promoted, and the new collagen can be systematically protected from oxidation and saccharification damage.

The present invention relates to a nutritional and health care composition for oral administration, comprising an extract of Glycyrrhiza glabra L. and an extract of Olea eupaea L.. The nutritional and health care composition is characterized in that the nutritional and health care composition comprises an extract of Glycyrrhiza glabra L. and an extract of Olea eupaea L.. The formulations are suitable for use as skin decolorizing and bleaching agents and for controlling skin protein saccharification.

Composition for the formulation of a herbal mouthwash, consisting of a liquid composition containing extracts of Glycyrrhiza glabra (licorice) and Camellia sinensis (green tea) dispersed in an aqueous-alcoholic base, providing antimicrobial and oral hygiene benefits.

The invention belongs to the technical field of cosmetic compositions, and particularly relates to a whitening composition based on a double supramolecular technology and a preparation method and application thereof. The invention provides a whitening composition which comprises the following components: glycyrrhiza glabra extract, a deep eutectic solvent and hydroxypropyl-beta-cyclodextrin, and integration of efficient extraction, stable inclusion and targeted delivery is realized through a double supramolecular synergistic technology of the deep eutectic solvent and the hydroxypropyl-beta-cyclodextrin.

The application relates to the cosmetic technical field, and particularly discloses a composition for micro-ecological balance and circadian rhythm repair and lightening and application. The composition for micro-ecological balance and circadian rhythm repair and lightening comprises the following components in mass percentage: glycyrrhiza glabra root extract 0.001%-1%, olea europaea leaf extract 0.1%-5%, hydraena elongata extract 0.1%-2%, gentiana rigescens 0.5%-3%, inulin 0.1%-5%, tripeptide-3 0.001%-0.01%, jasminum nudiflorum extract 0.5%-2%, and the balance is water. The composition has the advantages of systematically solving multiple problems such as skin redness, dullness and rhythm disorder.

The present application provides a kind of multi-target synergistic whitening and freckle lightening plant composition and its preparation method and application, belong to medical, dental or cosmetic preparation field.The active ingredient is composed of Radix Glycyrrhizae, Radix Scutellariae, Coix Seed, Centella asiatica and mulberry root-bark extract according to specific proportion.The composition realizes signal pathway inhibition, tyrosinase activity blocking, melanin transport interference, keratin metabolism acceleration and skin barrier repair by constructing multi-target synergistic network.The present application overcomes the limitations of single whitening target, such as repeated color spots and slow effect, realizes whole-cycle and systematic whitening and freckle lightening effect under the premise of ensuring safety, and is suitable for cosmetic field.

The present invention is in the field of feed additives for animals, e.g., farming animals, in particular feed additives to be added to animal feed to obtain an improved performance, e.g., an increasing feed intake, increasing average daily gain, increasing feed efficiency (i.e., decreasing feed conversion ratio), and / or increasing milk fat yield, of such animals.

The present invention relates generally to methods and compositions useful for concealing skin imperfections. The method can include applying a topical composition to facial skin, for example skin under the eye. The composition can include Glycyrrhiza glabra root extract, disteardimonium hectorite, trisiloxane, triethyl citrate, cetyl dimethicone, and cetyl PEG / PPG-10 / 1 dimethicone.

The invention relates to the technical field of cosmetics, in particular to a repairing and red fading composition based on a supercritical carbon dioxide extraction technology and a preparation method of the repairing and red fading composition. The repairing and red fading composition adopting the supercritical carbon dioxide extraction technology comprises a macadamia nut seed extract, an ampelopsis grossedentata leaf extract, a glycyrrhiza glabra root extract, a spanishneedles herb extract and a natural rose extract which are obtained through the supercritical carbon dioxide extraction technology. The supercritical carbon dioxide extraction technology comprises the following steps: mixing AEO-9 and deionized water to obtain a 5% (w / v) mixed solution, mixing the wolfberry glycosylated polypeptide and deionized water to obtain a 2% (w / v) mixed solution, and mixing the two mixed solutions by using ultrasonic waves according to a weight ratio of 3: 1; a mixture of fatty alcohol-polyoxyethylene ether (AEO-9) and Chinese wolfberry glycosylated polypeptide is used as an entrainer, so that the content of active ingredients of various plant raw material extracts is comprehensively increased, and finally, the composition has a better effect.

The invention relates to the technical field of cosmetics, and discloses an anti-wrinkle whitening cream mask and a preparation method thereof.The preparation method includes the steps that a W / O / W multiple emulsification system is constructed, an inner water phase contains nicotinamide, inositol hexaphosphate and acetyl hexapeptide-8, an outer water phase contains alpha-arbutin and glycyrrhiza glabra root extract, and the W / O / W multiple emulsification system is prepared; and double inhibition of tyrosinase and dynamic wrinkle targeted intervention are realized through double-path cooperation. The cream has high stability, slow release property and excellent rheological property, does not need preservatives, has good film-forming property, and remarkably improves the transdermal efficiency and chemical stability of active components. Through direct tyrosinase inhibition, copper ion chelation and neurotransmitter inhibition, the skin care composition has a clear dual whitening mechanism, a targeted anti-wrinkle mechanism, a high-stability multi-emulsion structure, excellent rheological properties and good skin feeling experience; the problems that in the prior art, a cream mask is loose in dosage form structure, uncontrollable in active ingredient release, fuzzy in action mechanism and limited in use scene are solved.

The invention discloses a mud film and a manufacturing method thereof. The mud mask is prepared from kaolin, butyrospermum parkii butter, a centella asiatica extract, a yeast extract, a polygonum cuspidatum root extract, a scutellaria baicalensis extract, a peony seed extract, a glycyrrhiza glabra extract, a perilla frutescens extract, a rosemary extract, a wolfberry extract, a cinnamon extract and other raw materials, and has the functions of relaxing tendons and activating collaterals, expelling wind and removing cold, promoting blood circulation to remove blood stasis, warming yang and dispelling cold, and replenishing qi to invigorate the spleen; the traditional Chinese medicine is suitable for meridian obstruction, wet and cold body and poor circulation metabolism.

The invention relates to a composition with a whitening effect and application thereof, and belongs to the technical field of cosmetics. The composition with the whitening effect is prepared from the following components in parts by mass: 1 to 3 parts of phenylethyl resorcinol, 0.1 to 0.5 part of hexapeptide-2, 0.1 to 0.3 part of compound PDRN and 2 to 4 parts of nicotinamide, wherein the compound PDRN is prepared from negundo chastetree leaf PDRN, glycyrrhiza glabra PDRN and desert rose PDRN in a mass ratio of 1 to (1 to 3) to (2 to 4). The composition with the whitening effect has a remarkable effect of inhibiting tyrosinase, and is mild, non-irritant and wide in applicability.

The invention relates to a fermentation composition containing liquorice, oat and orange peel as well as a preparation method and application of the fermentation composition. The composition comprises an oil phase component (containing squalane, cetostearyl alcohol, beeswax, magnesium stearate, polyglycerol-3-methyl grape distearate, sucrose stearate, ceramide NP and tocopherol) and a water phase component (containing a multi-bacteria symbiotic fermentation filtrate and deionized water, the filtrate is prepared from glycyrrhiza glabra, oat kernels and orange peel as raw materials, and the water phase component is prepared by mixing the glycyrrhiza glabra, the oat kernels and the orange peel. And carrying out symbiotic fermentation on plant lactobacillus, saccharomyces cerevisiae and aspergillus niger). Through a rubbing demulsification mechanism, a double-layer structure of'anti-oxidation and water locking of an oil phase outer layer and continuous slow release of a water phase inner layer 'is formed, so that the oxidation loss after the active matter is smeared is effectively reduced, and the transdermal efficiency and the efficacy durability are improved. The composition does not contain chemical stimulation components such as glucocorticoid in the whole process, is high in safety and is suitable for daily nursing of sensitive skin and allergy repair. The preparation method is simple and efficient, and the technical problem that the natural extract is easy to oxidize and inactivate after being smeared is solved.

The present application relates to the technical field of biology, and particularly provides a licorice stem cell line and application thereof. The licorice stem cell line of the present application has been preserved in the China General Microbiological Culture Collection Center, and has a preservation number of CGMCC No. 46600, is named as licorice stem cell strain gc001, has a high content of secondary metabolites, and can be directly used in high-end skin care products and medical products, and expands the value of licorice resources.