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37 results about "Gynostemma" patented technology

Gynostemma is a genus of perennial climbing vines in the cucumber, gourd, and melon family, comprising at least 19 species, all native to the tropical East or Far East, inclusive of the Himalayas: China (with 9 endemic); the islands of Japan; Malaysia; and New Guinea. The term Gynostemma is derived from Ancient Greek γυνή meaning "woman" or "female", and στέμμα meaning "wreath" or "garland". In (post-)classical Latin the form stemma is attested as Greek loanword. In Ancient Greek and Latin, stemma is of neuter gender. German-Dutch botanist Carl Ludwig Blume described Gynostemma from two species he named: G. pedata (later changed, to pedatum) and G. simplicifolia (also later changed, to simplicifolium). Neither species was clearly designated by him as the type; however, the former species, G. pedatum is now considered to be a synonym of G. pentaphyllum . The genus was published in 1825, in Carl Ludwig von Blume's Bijdragen tot de flora van Nederlandsch Indië ("Contributions to the flora of the Dutch East Indies").

Traditional Chinese medicine composition with effects of dispelling effects of alcohol and protecting liver as well as preparation method and application of traditional Chinese medicine composition

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with hangover-alleviating and liver-protecting effects and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: semen hoveniae, flos puerariae, rhizoma gastrodiae, pericarpium citri reticulatae, poria cocos, rhizoma alismatis, herba artemisiae scopariae, gynostemma pentaphylla, roasted rhizoma atractylodis macrocephalae, cortex magnoliae officinalis, radix paeoniae alba and honey-fried licorice root. The traditional Chinese medicine composition disclosed by the invention has the effects of relieving alcoholism, resolving damp turbidity, clearing liver and gallbladder and strengthening spleen soil. The traditional Chinese medicine composition disclosed by the invention is particularly suitable for patients suffering from alcohol fever, alcoholic liver, hyperlipidemia and liver and gall diseases mainly caused by damp turbidity and alcohol toxicity. Experimental results show that the traditional Chinese medicine composition has a good treatment effect on acute alcoholic liver injury and chronic alcoholic fatty liver, so that the traditional Chinese medicine composition has a relatively good development and utilization prospect.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

Gynostemma pentaphyllum tea bag and processing technology thereof

PendingCN122250527AOrganic active ingredientsNervous disorderEngineeringDendranthema boreale
This invention proposes a Gynostemma pentaphyllum tea bag and its processing technology, belonging to the field of tea bag technology. The tea bag comprises the following raw materials in parts by weight: 60-80 parts Gynostemma pentaphyllum, 6-12 parts wild chrysanthemum, 5-10 parts Acer truncatum tea, 3-6 parts nervonic acid microcapsules, and 4-8 parts licorice. The processing technology includes: raw material pretreatment, chopping, segmented roasting, pulverizing, mixing, sterilization, and packaging. This invention, through a unique formula design, effectively improves the bitter taste of Gynostemma pentaphyllum using licorice and wild chrysanthemum; it increases the water solubility of nervonic acid by utilizing the wall structure of the microcapsules, solving the problem of its insolubility in water, allowing nervonic acid to be effectively dissolved in the tea infusion, achieving the effects of brain nerve protection and repair. Simultaneously, the microcapsule protection system ensures its dispersibility and stability in the processing system; through the combination of segmented roasting and ultra-fine pulverization, it not only alleviates the cold nature of Gynostemma pentaphyllum but also significantly improves the extraction rate of effective components.
Owner:玉溪芳泽农业科技开发有限公司 +1

A composition with black hair efficacy and its use

PendingCN122272431AArginineTyrosine
This invention belongs to the technical field of daily-use shampoo and hair care raw materials, specifically relating to a composition with hair-darkening effects and its application. The composition with hair-darkening effects provided by this invention is formulated from a compound of Platycladus orientalis leaf extract, Polygonum multiflorum extract, Eclipta prostrata leaf extract, Gynostemma pentaphyllum extract, palmitoyl tetrapeptide-10, L-arginine, and decapeptide-4. By adjusting the types and amounts of each component, the interaction between the components is improved, thereby increasing the relative activity of tyrosinase and the relative content of melanin, indicating that the components have a synergistic effect and excellent hair-darkening efficacy. The hair-darkening composition obtained by this invention is applied to the preparation of shampoo, which exhibits excellent hair-darkening effects and high safety, and has broad market application value in the field of hair-darkening or hair-protecting products.
Owner:BAWANG(GUANGZHOU) CO LTD

Plant-derived bio-growth-promoting fertilizer and preparation method thereof

The application discloses a plant-source bio-growth-promoting synergistic fertilizer and a preparation method thereof. The fertilizer is prepared by compounding plant-source composite growth-promoting substances, a composite microbial flora and a carrier material in a specific mass ratio. The plant-source composite growth-promoting substances are prepared by solid-state fermentation and extraction of gynostemma pentaphyllum, astragalus and acanthopanax. The composite microbial flora contains brazilian nitrogen-fixing spirillum, fluorescent pseudomonas and brevibacillus brevis, and is embedded and fixed by using kappa-carrageenan microcapsules containing biochar nanoparticles. The carrier is lignosulfonate-modified nano-attapulgite. The application also provides a corresponding preparation method. The granular fertilizer is finally prepared through steps of activating the strains by a composite activation solution, embedding by microencapsulation and carrier loading granulation. The fertilizer combines the synergistic effect of plant-source active substances and functional microorganisms, significantly improves the activity of the flora and the field colonization capacity, and can effectively promote plant growth, improve crop yield and quality.
Owner:HUBEI BOHAI FERTILIZER GROUP CO LTD +1

Gynostemma pentaphyllum-derived triterpenoid saponin compound and use thereof in preparation of Anti-fatigue products

PCT designated stageWO2026149353A1TriterpeneTriterpenoid saponin
Provided are a Gynostemma pentaphyllum-derived triterpenoid saponin compound and a use thereof in the preparation of anti-fatigue products. The provided triterpenoid saponin compound is selected from one of compounds 1-29. Also provided are a use of a triterpenoid saponin compound as represented by general formula I in the preparation of anti-fatigue products. Experiments show that the Gynostemma pentaphyllum-derived triterpenoid saponin compound has significant anti-fatigue activity and can be used for preparing anti-fatigue products.
Owner:ACADEMY OF MILITARY MEDICAL SCIENCES

Resin for decoloring fiveleaf gynostemma herb as well as preparation method and application of resin

The invention belongs to the field of polymer chemistry, and particularly relates to a resin for decoloring gynostemma pentaphylla and a preparation method and application thereof, and the preparation method comprises the following steps: S1, mixing a water phase and an oil phase, standing, shaping, carrying out polymerization reaction, and removing a pore-foaming agent to obtain an acrylonitrile copolymer matrix resin; s2, mixing the acrylonitrile copolymer matrix resin with a first solvent, alkali and a nucleophilic reagent, and performing aminolysis reaction to obtain amide resin; and S3, mixing the amide resin with a second solvent, and carrying out Hofmann degradation to obtain the resin for decoloring the gynostemma pentaphylla. According to the preparation method, amide resin is prepared firstly and then converted into primary amine through Hofmann degradation, weak base functional groups can be connected to decolorizing resin, weak base resin with amino (-NH2) functional groups is prepared and used for decolorizing gynostemma pentaphylla, and the decolorizing rate is increased and the loss of active ingredients is reduced.
Owner:旬阳领盛新材料科技有限公司 +2

Method for promoting conversion of rare ginsenoside in gynostemma pentaphylla and treatment effect of prepared product on metabolic syndrome

The invention discloses a method for promoting conversion of rare ginsenoside in gynostemma pentaphylla and a therapeutic effect of a prepared product on metabolic syndrome. Specifically, the invention discloses a method for promoting conversion of rare ginsenoside in gynostemma pentaphylla, and the method comprises the following steps: (1) taking a proper amount of gynostemma pentaphylla medicinal material dried in the shade, crushing, and adding water for infiltration; (2) soaking for a period of time at a certain water bath temperature; (3) evaporating to dryness, adding ethanol or methanol with a certain concentration, carrying out heating reflux extraction or ultrasonic extraction, cooling an extracting solution, filtering, and carrying out vacuum concentration to obtain a concentrate; and (4) loading the concentrate on macroporous resin, adsorbing, eluting, and collecting the 60-80% ethanol elution part to obtain the total saponins dried in the shade. The method is mild in reaction condition, high in efficiency, high in specificity and free of pollution, and the prepared product is high in rare ginsenoside content and can be used for preventing and / or treating metabolic diseases such as non-alcoholic fatty liver diseases.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES +1

Schizophyllum strain and use thereof

ActiveCN122128115ABiocidePlant growth regulatorsBiotechnologySchizophyllum
This invention belongs to the field of microbial technology and discloses a strain of *Schizophyllum commune* that promotes seed germination in plants of the *Schizophyllum* genus. Schizophyllum commune The present invention provides strain pb5, with accession number CGMCC No. 42595. It also provides a microbial preparation containing strain pb5 and a method for promoting seed germination of *Gynostemma* species. The strain pb5 of this invention can promote the germination of *Gynostemma* species, especially *Gynostemma* seeds, and has significant application value for the sexual reproduction and resource conservation of *Gynostemma* species.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI

Tea packaging kit (Gynostemma pentaphyllum series 1)

ActiveCN309882661SProcess engineeringTea leaf
1. Name of the design product: Tea packaging set (Gynostemma pentaphylla series 1). 2. Use of the design product: The design product is used for packaging tea. 3. Design points of the design product: Combination of shape and pattern. 4. Picture or photo best indicating the design points: Refer to the drawings.
Owner:PINGLI SELENIUM RICH TEA CO LTD

A triple rpa-lfa rapid detection and visualization method for necrophagous flies

PendingCN122326762ABiotechnologygenomic DNA
A rapid detection and visualization method for triple RPA-LFA targeting necrophilic flies includes the following steps: Step 1: DNA amplification reaction; DNA is extracted from *Gynostemma pentaphyllum*, *Gynostemma spp.*, *Variegata spp.*, *Variegata spp.*, *Bulbus rubrothes*, *Gynostemma pentaphyllum*, *Flyflies fasciatus*, and *Heterodon spp.* using the SteadyPure Universal Genomic DNA Extraction Kit; the concentration and purity of the genomic DNA of the above species are assessed using a Nano Drop 2000 spectrophotometer; the reaction is performed according to the instructions of the DNA isothermal rapid amplification kit; the reaction system uses Buffer A, a primer mixture consisting of 3 pairs of primers; the mixture is incubated in a metal bath to perform the RPA reaction and obtain the amplified product; Step 2: Visual detection; Mixed amplification product: the amplified product is mixed with dd water to obtain a mixed amplification product; the mixed amplification product is dropped onto the LFD test strip sample pad, and then the result is displayed. This invention features no dependence on a sequencer, simple operation, rapid detection, and visualization.
Owner:CENT SOUTH UNIV

Formula of organic mixed health-care beverage and preparation method of organic mixed health-care beverage

PendingCN121730369AMilk substitutesBiotechnologyPyridoxine
The invention discloses a formula of an organic mixed health-care beverage and a preparation method of the organic mixed health-care beverage. The raw materials comprise, by weight, 1-3 g of ginseng, 1-3 g of deer-horn glue, 2-5 g of folium cortex eucommiae, 2-5 g of gynostemma pentaphylla, 2-5 g of hawthorn, 2-5 g of ligusticum wallichii, 1-3 g of schisandra chinensis, 3-5 g of rhizoma polygonati, 2-5 g of radix ophiopogonis, 100-200 mg of algal oil, 200-300 mg of taurine, 150-200 mg of grape seed extract, 3-5 ml of perilla seed oil, 50-80 ml of yoghourt, 30-50 ml of walnut juice and 30-50 ml of peanut liquid. The selenium-enriched beverage is prepared from 30 to 50 milliliters of sweet almond liquid, 30 to 50 milliliters of black sesame liquid, 30 to 50 milliliters of mango juice, 50 to 100 milliliters of apple juice, 30 to 50 milliliters of tomato juice, 50 to 80 micrograms of selenium-enriched yeast, 25 to 50 milligrams of vitamin C, 125 to 25 milligrams of vitamin E, 0 to 15 milligrams of vitamin B1 {thiamine}, 15 milligrams of vitamin B2 {riboflavin}, 0 to 15 milligrams of vitamin B2 {pyridoxine}, 15 milligrams of vitamin B6 {pyridoxine}, 25 milligrams of vitamin B9 {folic acid}, 40 micrograms of vitamin B9 {folic acid}, and 0 to 75 milligrams of vitamin B12 {cobalamin}. After being taken by various people for a period of time, the health-care food is smooth and delicious in taste and free of adverse reaction through evaluation in multiple aspects, and the health-care effect and feeling state of the health-care food are better than those of the prior art. And the health-care tea is suitable for a wide range of people, is beneficial to market promotion, and enables more people to achieve the health-care effect of preventing diseases before diseases.
Owner:韩荣辉

Application of gypenoside A in preparation of medicine for treating diseases caused by iron metabolism disorder

The invention provides novel application of gypenoside A. Verification shows that the gypenoside A can improve problems caused by cell iron ion accumulation by improving the level of cell iron metabolism related protein, and can be used for preparing medicines for treating diseases caused by iron metabolism disorder, such as neurodegenerative diseases, thalassemia and hemochromia.
Owner:SHENZHEN UNIV

Preparation method and application of Gynostemma pentaphyllum-derived vesicle composition

This invention discloses a method for preparing and applying a Gynostemma pentaphyllum-derived vesicle composition. The preparation method includes: crushing and extracting Gynostemma pentaphyllum with alcohol, followed by enzymatic hydrolysis and stabilization treatment with a combination of enzymes to obtain the Gynostemma pentaphyllum-derived vesicle composition. The preparation method of this invention can obtain Gynostemma pentaphyllum-derived vesicles with clear edges and high uniformity. The obtained Gynostemma pentaphyllum-derived vesicle composition has antioxidant, anti-inflammatory, hair-darkening, and anti-hair loss effects. It retains its complete vesicle structure even after 90 days of storage at room temperature, exhibiting the advantage of vesicle stability throughout the overall shelf life of the raw material and meeting the requirements of cosmetic raw materials. When applied to formulation systems, it does not show significant viscosity reduction, effectively avoiding formulation instability and deactivation.
Owner:BAIHONG HUASHANG BIOTECHNOLOGY (SHANDONG) GROUP CO LTD

Health-care tea capable of reducing three highs and preparation method thereof

The invention relates to the technical field of health-care tea, and particularly discloses health-care tea for reducing hypertension, hyperglycemia and hyperlipidemia and a preparation method thereof, and the health-care tea is prepared from the following components in parts by weight: 25-35 parts of radix puerariae, 15-20 parts of fiveleaf gynostemma herb, 10-15 parts of folium mori, 8-12 parts of flos sophorae, 10-15 parts of semen cassiae, 5-8 parts of spica prunellae and 5-8 parts of radix astragali. Wherein the puerarin content of the radix puerariae is greater than or equal to 6.0%, and the gynostemma pentaphyllum saponin content of the gynostemma pentaphyllum is greater than or equal to 5.0%. The invention has the following beneficial effects: 1, radix puerariae and gynostemma pentaphyllum are matched to expand blood vessels and improve blood circulation; mulberry leaves and sophora flowers jointly inhibit glycolipid absorption; semen cassiae has the effects of relaxing bowel and reducing lipid accumulation; prunella vulgaris clears heat and reduces pressure, radix astragali tonifies qi and strengthens root, multiple targets cooperate to stabilize blood pressure, blood sugar and blood fat levels, all the raw materials are simple and common, and the cost is low. 2, plant cell walls are broken through enzymolysis pretreatment, and key components such as puerarin, gypenoside and rutin are fully extracted in combination with ethanol-water two-phase extraction; the ultrasonic-assisted technology accelerates dissolution, so that thermosensitive substances are prevented from being damaged by high temperature, and the drug effect is retained to the maximum extent.
Owner:朱明友

A targeted thermosensitive drug-loaded composite microsphere based on attapulgite

This invention discloses a targeted, temperature-sensitive drug-loaded composite microsphere based on attapulgite, comprising primary drug-loaded composite microspheres and lauric acid. The primary drug-loaded composite microspheres include purified attapulgite, gypenosides, inulin, and folic acid. Gynostemma pentaphyllum saponins, inulin, and folic acid are adsorbed onto a mesoporous structure composed of purified attapulgite rod crystals. The surface rigid structure of the primary drug-loaded composite microspheres includes a large number of interlaced channels. Lauric acid is encapsulated within the surface rigid structure of the primary drug-loaded composite microspheres. The mass percentages of purified attapulgite, gypenosides, inulin, and folic acid are: 50-85 parts: 10-30 parts: 10-25 parts: 0.1-1 parts; the mass ratio of the primary drug-loaded composite microspheres to lauric acid is 1:2 to 1:3. This application not only enables temperature-controlled "on-off" drug release, significantly improving drug targeting and therapeutic precision, but also reduces the systemic toxicity of chemotherapy at its source, achieving highly efficient and low-toxicity synergistic therapy.
Owner:CHONGQING UNIV

Method for promoting conversion of rare ginsenoside in gynostemma pentaphylla and treatment effect of prepared product on metabolic syndrome

The invention discloses a method for promoting conversion of rare ginsenoside in gynostemma pentaphylla and a therapeutic effect of a prepared product on metabolic syndrome. Specifically, the invention discloses a method for promoting conversion of rare ginsenoside in gynostemma pentaphylla, and the method comprises the following steps: (1) taking a proper amount of gynostemma pentaphylla medicinal material dried in the shade, crushing, and adding water for infiltration; (2) soaking for a period of time at a certain water bath temperature; (3) evaporating to dryness, adding ethanol or methanol with a certain concentration, carrying out heating reflux extraction or ultrasonic extraction, cooling an extracting solution, filtering, and carrying out vacuum concentration to obtain a concentrate; and (4) loading the concentrate on macroporous resin, adsorbing, eluting, and collecting the 60-80% ethanol elution part to obtain the total saponins dried in the shade. The method is mild in reaction condition, high in efficiency, high in specificity and free of pollution, and the prepared product is high in rare ginsenoside content and can be used for preventing and / or treating metabolic diseases such as non-alcoholic fatty liver diseases.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES +1

Camellia seed oil diglyceride composition for relieving, removing wrinkles, removing blackness and improving eyesight, eye pad and preparation method

The invention discloses a camellia oleosa seed oil diglyceride composition for relieving, removing wrinkles, removing blackness and improving eyesight, an eye pad and a preparation method, and relates to the technical field of eye pads. The camellia oleosa seed oil diglyceride composition comprises the following raw materials: camellia oleosa seed oil diglyceride, a cynanchum atratum extract, a tremella sporocarp extract, a pepper root extract, a gynostemma pentaphyllum extract, a cornflower extract and a purslane extract. The camellia oleosa seed oil diglyceride composition disclosed by the invention can synergistically realize four effects of relieving and repairing, resisting and lightening wrinkles, removing black and brightening, and improving eyesight and protecting eyes under specific components and proportions, is mild and non-irritant, and is suitable for eye care requirements of multiple skin types.
Owner:广东善百年特医食品有限公司

Tea packaging kit (gynostemma pentaphyllum leaf tea series)

ActiveCN309691436SBiotechnologyTea leaf
1. Name of the design product: Tea packaging set (Gynostemma pentaphylla leaf tea series). 2. Use of the design product: The design product is used for packaging tea. 3. Design points of the design product: Combination of shape and pattern. 4. Picture or photo best indicating the design points: Refer to the drawings.
Owner:PINGLI SELENIUM RICH TEA CO LTD

A compound paclitaxel broad-spectrum anticancer traditional Chinese medicine preparation and a preparation method thereof

The application provides a compound paclitaxel broad-spectrum anticancer traditional Chinese medicine preparation and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The compound paclitaxel broad-spectrum anticancer traditional Chinese medicine preparation is prepared from the following components in a mass fraction: 0.5-2.0 parts of paclitaxel powder with a purity of 99%, 18-30 parts of Herba Lysimachiae, 18-30 parts of Herba Impatientis, 18-30 parts of Radix Scrophulariae, 14-25 parts of Radix Curcumae, 14-25 parts of Radix Pini Strobil, 14-25 parts of Gynostemma pentaphyllum, 14-25 parts of Citrus medica, 10-18 parts of Radix Paeoniae Alba, 10-18 parts of Radix Paeoniae Rubra, 10-18 parts of Radix Rabdosiae, 6-12 parts of Fructus Schisandrae, 6-12 parts of Lumbricus, and 6-12 parts of Radix Glycyrrhizae. The compound paclitaxel broad-spectrum anticancer traditional Chinese medicine preparation can not only significantly inhibit the growth of tumor cells on a lung cancer patient, but also significantly reduce bone marrow suppression and immune function damage caused by paclitaxel.
Owner:JIANGSU SHANDONG BIOTECHNOLOGY GRP CO LTD

Tea packing barrel

1. Name of the designed product: Tea packaging barrel (Pingli gynostemma series). 2. Use of the designed product: The designed product is used for packaging tea. 3. Design points of the designed product: Combination of shape and pattern. 4. Picture or photo that best indicates the design points: Design 1 perspective view. 5. Design 1 is designated as the basic design.
Owner:PINGLI SELENIUM RICH TEA CO LTD

A composition with antioxidant function and exosome structure protection and a preparation method and application thereof

The application discloses a composition with antioxidant function and exosome structure protection effect and a preparation method and application thereof. The composition with antioxidant function and exosome structure protection effect is prepared by compounding gynostemma pentaphyllum exosomes with an exosome protective agent, a first preservative and other components to form a stable composite system, which not only effectively protects the gynostemma pentaphyllum exosome structure, but also obviously improves the antioxidant capacity of the gynostemma pentaphyllum exosomes. The composition still has a regular shape, a clear boundary and a tea tray-shaped vesicle structure under long-time placement at 45 DEG C, and a cosmetic prepared by using the composition has an obvious effect of improving cell viability, which indicates that the composition has excellent structure stability and antioxidant function, and provides important data support for developing a cosmetic with more excellent antioxidant efficacy.
Owner:BAIHONG HUASHANG BIOTECHNOLOGY (SHANDONG) GROUP CO LTD

Artificial breeding method of hybrid salamander

ActiveCN120660646BMicrobial agentAstaxanthin
The application provides an artificial breeding method of Pseudobagrus vachelli hybrid, and relates to the field of aquaculture.The artificial breeding method of Pseudobagrus vachelli hybrid comprises the following steps: (1) parent selection; (2) parent cultivation: feeding female parent fish feed I and male parent fish feed II three months before breeding; feed I raw materials: fish meal, soybean meal, corn meal, astaxanthin, beta-glucan, compound microbial agent, compound A; feed II raw materials: fish meal, squid meal, saltwort powder, astaxanthin, rosemary acid, compound microbial agent, compound B; compound microbial agent raw materials: Bacillus ligniniphilus, Bacillus pumilus and Bacillus natto; compound A raw materials: Dendrobium officinale, Gynostemma pentaphyllum, ramie root, Aralia decaisneana leaf and perilla seed; compound B raw materials: sea horse, Cistanche, Acanthopanax, water caltrop shell and moringa seed; (3) fertilization and hatching to obtain fry.The application has the advantages of high egg-laying amount of Pseudobagrus vachelli hybrid single-tail female fish, high fertilization rate and high hatching rate, and reduces fry deformity.
Owner:HAINAN CHENHAI AQUATIC CO LTD

Fresh gynostemma pentaphyllum exosome and preparation method and application thereof

PendingCN122344545ANematodePharmaceutical drug
The present application relates to the technical field of biological medicine, in particular to a fresh product gynostemma pentaphyllum exosome and a preparation method and application thereof. The preparation method comprises the following steps: crushing the fresh product gynostemma pentaphyllum, adding a buffer solution to homogenate, filtering, and obtaining a primary extract; performing multi-stage differential centrifugation on the primary extract, removing impurities, and collecting supernatant; performing ultracentrifugation enrichment on the supernatant, collecting the precipitate and resuspending, and obtaining the fresh product gynostemma pentaphyllum exosome. The nematode experiment shows that the fresh product gynostemma pentaphyllum exosome can significantly prolong the lifespan of Caenorhabditis elegans, enhance the movement ability, reduce the accumulation of lipofuscin related to aging, and improve the heat stress survival rate. The fresh product gynostemma pentaphyllum exosome provided by the present application has clear components, good uniformity, and significant anti-aging activity, can provide material evidence for the scientific connotation of the "different use of raw and cooked" of gynostemma pentaphyllum, and be applied to the preparation of drugs for delaying aging, enhancing stress resistance, or preventing and treating neurodegenerative diseases, and has high scientific research value and clinical application prospect.
Owner:EXPERIMENTAL RES CENT CHINA ACAD OF CHINESE MEDICAL SCI

Application of gynostemma pentaphylla polysaccharide in preparation of medicine for treating ulcerative colitis

The invention discloses application of fiveleaf gynostemma herb polysaccharide in preparation of medicine for treating ulcerative colitis, the main structure of the fiveleaf gynostemma herb polysaccharide is shown in the specification, research proves that the prepared fiveleaf gynostemma herb polysaccharide has an excellent treatment effect on ulcerative colitis for the first time, activation of NLRP3 inflammasome is inhibited by activating an NRF2 anti-oxidation pathway, and the curative effect of the fiveleaf gynostemma herb polysaccharide on ulcerative colitis is improved. The bacterial flora abundance of bacteroides and thick-walled mycophylum is increased, and the bacterial flora abundance of proteobacteria is reduced, so that the ROS level is reduced, the inflammatory response is reduced, and the intestinal mucosal barrier repair of DSS mice is promoted.
Owner:SHENZHEN TRADITIONAL CHINESE MEDICINE HOSPITAL

Method for purifying polycyclic aromatic hydrocarbons by using gynostemma pentaphyllum extract

The application provides a method for purifying polycyclic aromatic hydrocarbons (PAHs) in gynostemma extract, and the presence of PAHs in gynostemma extract is found for the first time, and the PAHs in the gynostemma extract are removed in a targeted manner, wherein the purification process is to remove the PAHs in the extract by using activated carbon under specific conditions, and the gynostemma extract is dissolved more fully by selecting ethanol solution as a solvent and controlling the dissolving process, so as to provide a basis for subsequent purification, and the activated carbon purification process is optimized, the amount of activated carbon and the purification temperature are controlled, and the content of PAHs in the gynostemma extract is greatly reduced by adjusting the overall solvent process and the purification process, and the loss of the gynostemma extract is reduced. The whole process is simple, cost-effective, environmentally friendly, can obviously improve the quality of the extract, and meets the strict quality standards.
Owner:NINGBO BEILUN EXCARE PHARMA TECH

Flavored chewable tablet for old pets and production process of flavored chewable tablet

PendingCN121512092AAnimal feeding stuffAccessory food factorsBiotechnologyFlavoring essences
The invention relates to flavored chewable tablets for old pets and a production process of the flavored chewable tablets. The preparation method comprises the following steps: respectively extracting sea-buckthorn, acanthopanax and semen cuscutae for at least one time to respectively obtain corresponding filtrate and filter residues, and respectively refrigerating the filtrate and the filter residues; the extraction treatment comprises smashing, ethanol presoaking and filtering; the preparation method comprises the following steps: cutting gynostemma pentaphyllum into pieces, pre-soaking with water, adding filter residues of sea-buckthorn, acanthopanax and semen cuscutae, and uniformly mixing to obtain a compound; boiling and filtering the compound at least once, and drying filtrate to obtain extract powder A; meanwhile, the sea-buckthorn, the acanthopanax and the semen cuscutae are uniformly mixed, decompressed and dried, and extract powder B is obtained; uniformly mixing the extract powder A, the extract powder B, mannitol, microcrystalline cellulose, sodium carboxymethyl starch, magnesium stearate, beef flavor powder and beef flavor essence, tabletting, and coating, so as to obtain the flavor chewable tablet for old pets to reduce abnormal unhairing phenomenon, enhance the body activity and improve the movement flexibility. The preparation method comprises the following steps: uniformly mixing the extract powder A, the extract powder B, mannitol, microcrystalline cellulose, sodium carboxymethyl starch, magnesium stearate, beef flavor powder and beef flavor essence;
Owner:CHONGQING XINONGDA KEXIN ANIMAL PHARM CO LTD

Gynostemma pentaphyllum extract and use thereof in preparation of Anti-fatigue product

PCT designated stageWO2026149356A1Chemical compoundBiochemistry
A Gynostemma pentaphyllum extract and the use thereof in the preparation of an anti-fatigue product. The Gynostemma pentaphyllum extract comprises one or more of the following compounds: (1) gypenoside LXXXV II; (2) (3β,12β,20S)-trihydroxydammar-24-en-3-O-[β-D-glucopyranosyl(1→2)-β-D-glucopyranosyl]-20-O-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside; (3) gypenoside V; (4) (3β,12β,20S)-trihydroxydammar-24-en-3-O-[6-O-acetyl-β-D-glucopyranosyl(1→2)-β-D-glucopyranosyl]-20-O-β-D-xylopyranosyl(1→3)-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside; (5) gypenoside LXXXVIII; (6) gypenoside X; (7) (3β,12β,20R)-trihydroxy-25-hydroperoxydammar-25-en-3-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside; and (8) (3β,12β,20S)-trihydroxy-24S-hydroperoxydammar-25-en-3-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside; and (9) gypenoside LXXXVI. The provided Gynostemma pentaphyllum extract has a significant anti-fatigue effect.
Owner:ACADEMY OF MILITARY MEDICAL SCIENCES

Preparation technology of fiveleaf gynostemma herb herbal tea beverage capable of clearing fire and reducing dryness

The invention discloses a preparation process of a fiveleaf gynostemma herb herbal tea beverage capable of clearing away fire and reducing dryness, and relates to the technical field of herbal tea beverage preparation. According to the process, fiveleaf gynostemma herb is used as a core raw material, and is matched with various medicinal and edible food materials such as lily, radix ophiopogonis and radix polygonati officinalis to prepare the fiveleaf gynostemma herb herbal tea beverage. The herbal tea beverage is prepared through the steps of raw material pretreatment, composite enzymolysis, ultrasonic and microwave synergistic extraction, multistage filtration, blending and homogenizing, sterilization and filling and the like, the extraction rate of active ingredients is increased by adopting a composite enzymolysis and ultrasonic and microwave synergistic extraction process, and the stability of the herbal tea beverage is further improved by combining multistage filtration and stabilization treatment; therefore, the taste can be optimized through the accurate sugar-acid ratio, the problems that an existing gynostemma pentaphylla herbal tea is not remarkable in effect, low in extraction rate, poor in stability, poor in taste and the like are solved, the product has the effects of clearing away the heart-fire, moistening the lung, promoting the secretion of saliva or body fluid, relieving sore-throat, enhancing the immunity and the like, and the gynostemma pentaphylla herbal tea is fresh and cool in flavor, high in stability, long in shelf life and suitable for large-scale production and market popularization.
Owner:PINGLI COUNTRY TIANZHEN TEA CO LTD

Method for promoting conversion of rare ginsenoside in gynostemma pentaphylla and treatment effect of prepared product on metabolic syndrome

The invention discloses a method for promoting conversion of rare ginsenoside in gynostemma pentaphylla and a therapeutic effect of a prepared product on metabolic syndrome. Specifically, the invention discloses a method for promoting conversion of rare ginsenoside in gynostemma pentaphylla, and the method comprises the following steps: (1) taking a proper amount of gynostemma pentaphylla medicinal material dried in the shade, crushing, and adding water for infiltration; (2) soaking for a period of time at a certain water bath temperature; (3) evaporating to dryness, adding ethanol or methanol with a certain concentration, carrying out heating reflux extraction or ultrasonic extraction, cooling an extracting solution, filtering, and carrying out vacuum concentration to obtain a concentrate; and (4) loading the concentrate on macroporous resin, adsorbing, eluting, and collecting the 60-80% ethanol elution part to obtain the total saponins dried in the shade. The method is mild in reaction condition, high in efficiency, high in specificity and free of pollution, and the prepared product is high in rare ginsenoside content and can be used for preventing and / or treating metabolic diseases such as non-alcoholic fatty liver diseases.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES +1

Method for synchronously cleaning cultivation bottle and gastrodia elata in bottle, solid medium and swinging device

The invention discloses a synchronous cleaning method for a cultivation bottle and gastrodia elata in the bottle, a solid medium and a swinging device. The method comprises the following steps: introducing a liquid medium and a solid medium for cleaning into the cultivation bottle; the cultivation bottle swings in a reciprocating mode, the liquid medium and the solid medium in the cultivation bottle move relative to the cultivation bottle and the gastrodia elata, and cleaning is completed. The solid medium is formed by mixing a cynanchum otophyllum block, a birch block and a Chinese fir block; in parts by mass, 1-2 parts of the cyan clover wood block, 2-4 parts of the birch wood block and 0.5-2 parts of the Chinese fir wood block are used. The swinging device comprises a support; the swinging assembly comprises a motor, a transmission shaft and a swinging bin; wherein the transmission shaft is an eccentric transmission shaft and is used for converting the rotary motion of the motor into the reciprocating swing motion of the swing bin. On the basis of guaranteeing the cleaning effect and the product perfectness ratio, the production efficiency can be improved to a certain extent.
Owner:LESHAN JINKOUHE SENBAO WILD PLANT DEV CO LTD