Sobering up and liver protecting Chinese medicine prepn and its prepn process

A technology for sobering up the liver and protecting the liver, and traditional Chinese medicine. It is applied in the fields of medical formula, pill delivery, and drug combination. cost effect

Inactive Publication Date: 2007-03-21
FUZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Due to the complex chemical composition of Chinese medicinal materials, the extracts prepared by the water extraction process used in traditional Chinese medicine contain flavonoids, saponins, alkaloids and other main medicinal active ingredients for sobering up and protecting the liver, but also contain a large amount of protein, polysaccharides, essential oils, and tannins. , vitamins, inorganic salts and organic acids and other inactive impurities, the product obviously has defects such as easy moisture absorption, difficulty in storage, low purity of active ingredients such as flavonoids, saponins, alkaloids, and low content of active ingredients for sobering up an

Method used

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Examples

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preparation example Construction

[0020] The preparation method of the traditional Chinese medicine extract of the present invention is as follows: Pueraria japonica, Hovenia dulcis, Gynostemma pentaphylla, Lvyi citrus aurantium, licorice and gardenia are respectively pulverized into coarse powder, and the final concentration is 9 to 15 times the amount of medicinal materials (W / W). It is a 30%-70% polar organic solvent aqueous solution, extracted 1-3 times at 50°C-80°C, 1-3 hours each time, combined the extracts, filtered, recovered the solvent under reduced pressure, and concentrated in a vacuum to form a traditional Chinese medicine extract. paste.

[0021] The preparation method of the traditional Chinese medicine compound of the present invention is as follows: Pueraria lobata root and Poria cocos are pulverized into fine powder respectively, added to the above-mentioned traditional Chinese medicine extract, mixed evenly, and dried to prepare the Chinese medicine compound for sobering up alcohol and protec...

Embodiment 1

[0027] Pueraria japonica, Hovenia dulcis, Jiaogulan, Lvyi Zhishi, licorice, gardenia and other medicinal materials were respectively crushed to 16-30 mesh coarse powder, according to the formula (25% Pueraria japonica, 30% Hovenia dulcis, 10% Jiaogulan, green Aurantium aurantii 6%, Glycyrrhiza 10%, Gardenia 3%) take materials, add 70% ethanol aqueous solution of 15 times the amount of medicinal materials (W / W), extract at 80°C for 1 hour, filter, and recover under reduced pressure The solvent is concentrated into a hangover-protecting liver traditional Chinese medicine extract, and experiments show that the extraction rate is 10.7%.

[0028] Pueraria lobata and Poria cocos were respectively crushed into fine powders over 100 meshes, taken according to the formula (10% Pueraria lobata, 6% Poria cocos), added to the above-mentioned traditional Chinese medicine extract, mixed evenly, and spray-dried to obtain the Chinese medicine compound for hangover and liver protection.

[002...

Embodiment 2

[0031] Pueraria japonica, Hovenia dulcis, Jiaogulan, Lvyi Zhishi, licorice, gardenia and other medicinal materials were respectively pulverized into coarse powders of 16-30 meshes, according to the formula (25% of Pueraria japonica, 30% of Hovenia dulcis, 3% of Jiaogulan, green Aurantium aurantium 7%, Radix Glycyrrhizae 8%, Fructus Gardeniae 8%) take materials, add 60% ethanol aqueous solution of 13 times medicinal material amount (W / W), leaching 2 times under the condition of 65 ℃, each time 2 hours, The extracts were combined, filtered, the solvent was recovered under reduced pressure, and concentrated into a hangover-protecting liver traditional Chinese medicine extract. Experiments showed that the extraction rate was 10.6%.

[0032] Pueraria lobata and Poria cocos were crushed into fine powders of over 100 mesh respectively, and materials were taken according to the formula (10% of Pueraria lobata root and 6% of Poria cocos), added to the above-mentioned traditional Chinese...

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PUM

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Abstract

The present invention relates to one kind of sobering up and liver protecting Chinese medicine preparation and its preparation process. The Chinese medicine preparation is prepared with kudzu vine flower 6-50 wt%, trifoliate orange seed 6-40 wt%, gynostemma pentaphylla 1-18 wt%, Citrus seed 1-18 wt%, licorice 1-18 wt%, cape jasmine 1- 18 wt%, kudzu vine root 3-18 wt%, and tuckahoe 3-18 wt%. The preparation process includes crushing the Chinese medicinal materials into meal, extracting in water solution of polar organic solvent, merging the extracted liquid, filtering, decompression recovering the solvent, and concentrating to obtain extractum. The present invention has easy taking, obvious curative effect and no toxic side effect.

Description

Technical field: [0001] The invention relates to a green chemical preparation method for extracting medicinal active ingredients from plants, and more specifically relates to a traditional Chinese medicine medicament for sobering up alcohol and protecting the liver and a preparation method thereof. Background technique: [0002] The human body's catabolism of alcohol is a normal physiological phenomenon. A small amount of ethanol in the body can be catabolized into acetic acid under the action of alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH), and finally converted into acetic acid through oxidation. CO 2 and H 2 O is excreted from the body, but the excess ethanol is easily converted into free radicals because it cannot be metabolized and decomposed in time, causing a series of body dysfunction and symptoms of alcoholism. [0003] A large number of studies have shown that the activation of fat storage cells after long-term drinking plays a major role in ...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/00A61K9/14A61K9/16A61K9/20A61K9/48A61P25/32A61P1/16
Inventor 陈剑锋郭养浩陈浩
Owner FUZHOU UNIV
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