93 results about "Hovenia dulcis" patented technology

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating liver depression and spleen deficiency syndrome metabolism-related fatty liver disease, which is prepared from the following raw materials in parts by weight: 8 to 10 parts of ginseng, 10 to 15 parts of radix bupleuri, 10 to 15 parts of radix curcumae, 6 to 9 parts of ginger processed pinellia, 6 to 10 parts of fructus amomi, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of semen hoveniae, 10 to 15 parts of radix rehmanniae, 8 to 10 parts of rhizoma polygoni cuspidati and 6 to 9 parts of lignum dalbergiae odoriferae. The traditional Chinese medicine composition is used for treating the metabolism-related fatty liver diseases from the aspects of liver depression, spleen deficiency and phlegm-blood stasis, starts from the core pathological chain of liver depression, spleen deficiency, phlegm-dampness and blood stasis, has the functions of soothing the liver, tonifying the spleen, resolving dampness, reducing fat and promoting blood circulation to remove meridian obstruction, and is particularly suitable for patients with liver depression, spleen deficiency and metabolism-related fatty liver diseases. Clinical tests prove that the traditional Chinese medicine composition has a good treatment effect on patients with liver depression and spleen deficiency syndrome metabolism-related fatty liver diseases, the total effective rate reaches 94% or above, and the traditional Chinese medicine composition is mild in medicine property, good in safety, stable in curative effect, not prone to relapse and suitable for being taken for a long time.

The application discloses a composition for protecting liver and strengthening kidney and reducing uric acid, which is made of the following raw material components: Anoectochilus roxburghii, dried tangerine or orange peel, chicory, gardenia, turmeric, Hovenia dulcis Thunb, Cistanche deserticola Y.C.Ma, Rehmannia glutinosa, potassium citrate, sodium citrate and goose myo-peptide. The composition combines the immortal concept of TCM (Traditional Chinese Medicine) "treating disease from the root" and the uric acid control method of modern nutritional medicine as an organic whole, and achieves multiple effects of protecting liver and strengthening kidney, mutual benefit of yin and yang and reducing uric acid through multiple action targets. Animal experiment results show that the composition can effectively reduce the activities of transaminase ALT and AST, relieve liver damage, reduce serum creatinine level and improve urea ammonia excretion rate, improve kidney function, inhibit the activities of xanthine oxidase and adenosine dehydrogenase and reduce uric acid level. The composition is safe and has no toxic side effects, is suitable for people with insufficient liver and kidney functions and hyperuricemia and has a wide application prospect.

The invention discloses a hangover alleviating composition and a preparation method and application thereof, and belongs to the technical field of hangover alleviating, the hangover alleviating composition is prepared by taking hovenia acerba flavone, pueraria flavone and mulberry polysaccharide as functional components and taking chaff fruit polysaccharide as a synergist, the hovenia acerba flavone, pueraria flavone and mulberry polysaccharide play a hangover alleviating effect, and the hangover alleviating effect is achieved. The chaff fruit polysaccharide is used for synergism, so that the sobering time is greatly shortened, and the sobering effect is improved.

The invention provides a composition for assisting in protecting chemical liver injury as well as a preparation method and application thereof, and relates to the technical field of medicines. The composition for assisting in protecting the chemical liver injury comprises the following raw material components: radix puerariae, lucid ganoderma, hovenia dulcis thunb, schisandra chinensis, turmeric, Chinese yam, liquorice, Chinese dates, dandelion, chrysanthemum, radix polygonati officinalis and pericarpium citri reticulatae. The components are decocted and extracted with water, the extracting solutions are mixed and dried, and the obtained composition has the function of assisting in protecting chemical liver injury, is applied to products with the effects of improving damaged liver cells, reducing transaminase, reducing blood fat and improving the form of the liver and is remarkable in effect. The composition provided by the invention can effectively improve chemical liver injury of model mice within the dose range of each component, and has similar drug effects compared with a clinically applied drug silymarin.

The invention discloses a rumex hanus plant compounded tablet candy capable of dispelling the effects of alcohol and protecting the liver and a preparation method of the rumex hanus plant compounded tablet candy capable of dispelling the effects of alcohol and protecting the liver. Comprising the following raw materials in parts by weight: 15-25 parts of rumex hanus, 10-20 parts of arabinose, 10-15 parts of radix puerariae powder, 8-12 parts of hovenia dulcis thunb powder, 8-10 parts of silybum marianum seed oil microcapsule powder, 5-8 parts of L-glutamine, 3-5 parts of an acid-base regulator and 13-20 parts of auxiliary materials. The invention relates to rumex hanus plant compounded tablet candies capable of dispelling effects of alcohol and protecting liver. According to the invention, rumex hanus is taken as a core raw material, and through component compounding and process optimization, the tabletted candy which takes the rumex hanus active component as a leading component and has multiple target points for dispelling effects of alcohol and protecting liver is prepared, so that triple effects of intestinal barrier protection, alcohol metabolism acceleration and hepatocyte repair are realized. The prepared functional food with rumex hanus as the core is used for preventing drunkenness before drinking, reducing alcohol absorption during drinking, accelerating sobering after drinking and repairing liver and intestine injury caused by alcohol, and is particularly suitable for high-frequency drinking crowds and crowds with vulnerable liver functions.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with an effect of preventing and treating alcoholic liver injury as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: radix puerariae, turmeric, ginseng, hovenia dulcis thunb, white hyacinth bean, raw oyster shell, poria cocos, raw hawthorn, biond magnolia flower, juncus effuses and albizia flower. The traditional Chinese medicine composition has the effects of soothing liver and harmonizing stomach, dispelling alcohol effect and enlivening spleen, and reinforcing qi and nourishing blood. Experimental results show that the traditional Chinese medicine composition has a good treatment effect on acute alcoholic liver injury and chronic alcoholic fatty liver, and can effectively improve the symptoms of chest rib swelling pain, reduced appetite, anorexia, abdominal distension, hiccup, belching, borborygmus and qi and loose stool caused by liver-stomach disharmony and spleen deficiency and dampness of alcoholic liver injury patients; therefore, the method has good development and utilization prospects.

The invention provides a traditional Chinese medicine composition with anti-drunkenness and sobering-up functions as well as a preparation method and application thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5 to 40 parts of polygala fallax hemsl, 20 to 40 parts of radix puerariae, 20 to 40 parts of flos puerariae, 20 to 40 parts of semen hoveniae, 5 to 15 parts of fructus amomi, 10 to 30 parts of pericarpium citri reticulatae, 10 to 30 parts of fructus lycii and 1 to 3 parts of multivitamins. The preparation method comprises the following steps: weighing Polygala fallax Hemsl., Radix Puerariae, Flos Puerariae, Semen Hoveniae, Fructus Amomi, Pericarpium Citri Reticulatae and Fructus Lycii according to a ratio; decocting the mixed raw materials with water for at least one time, collecting and combining decoction, concentrating to obtain a Chinese herbal medicine concentrated solution, and mixing the Chinese herbal medicine concentrated solution with a multivitamin solution to obtain the traditional Chinese medicine composition with a preset dosage form. According to the traditional Chinese medicine composition, the polygala fallax hemsl is matched with various medicinal and edible traditional Chinese medicinal materials, and various vitamins are supplemented, so that drunkenness can be effectively prevented, and drunkenness time can be shortened.

The application provides application of a Codonopsis lanceolata composite fruit vinegar in preparation of a drug for preventing and treating acute liver injury, and belongs to the technical field of medicines.The Codonopsis lanceolata composite fruit vinegar is prepared from Codonopsis lanceolata as raw material and a composite fermentation fruit vinegar prepared from Pueraria lobata and Hovenia dulcis as research object, an acute alcoholic liver injury model of mice is established, the activities of ALT and AST in serum of the mice and the contents of TC, TG, LDL-C and HDL-C in serum of the mice and the contents of SOD, MDA and GSH in liver tissue of the mice are determined, and pathological sections of the livers of the mice are used as evaluation indexes, and it is found that the Codonopsis lanceolata composite fruit vinegar has a remarkable prevention and treatment effect on acute alcoholic liver injury.

The invention belongs to the technical field of traditional Chinese medicine extraction, and particularly relates to hovenia dulcis thunb powder with a hangover alleviating effect and a preparation method thereof. Comprising the following steps: (1) mixing hovenia dulcis thunb powder and water to obtain a mixed solution; (2) adding a compound enzyme into the mixed solution for enzymolysis to obtain an enzymatic hydrolysate A; (3) adding laccase into the enzymatic hydrolysate A for enzymolysis to obtain enzymatic hydrolysate B; (4) adding tannase into the enzymatic hydrolysate B for enzymolysis to obtain enzymatic hydrolysate C; (5) adding an alcohol solvent into the enzymatic hydrolysate C for extraction, carrying out solid-liquid separation, and concentrating and drying supernate to obtain hovenia dulcis thunb powder; wherein the compound enzyme comprises cellulase, pectinase and hemicellulose. According to the method, the contents of quercetin, myricetin, dihydromyricetin and spinosin in the hovenia dulcis thunb powder can be remarkably increased.

The invention discloses a traditional Chinese medicine composition for preventing and treating alcoholic liver injury, and relates to the technical field of traditional Chinese medicines, and the traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 10 to 15 parts of radix puerariae, 6 to 12 parts of semen hoveniae, 6 to 10 parts of radix angelicae sinensis, 6 to 10 parts of fructus lycii and 2 to 5 parts of liquorice root. Based on the treatment rule of'dispelling effects of alcohol, regulating qi and blood and tonifying liver and kidney 'in traditional Chinese medicine, medicinal and edible traditional Chinese medicines such as radix puerariae and hovenia dulcis thunb are primarily screened, and meanwhile, a'multi-target synergistic mechanism' predicted by network pharmacology is constructed and converted into a quantifiable treatment effect. The experimental data not only verifies the key pathway of GO / KEGG enrichment, but also systematically verifies the compound liver protection effect through multi-scale indexes such as visceral organ indexes, serum enzymology, histopathology and the like. The research not only provides a novel compound with a clear mechanism for ALD, but also demonstrates the feasibility of driving the precise design of a traditional Chinese medicine compound by network pharmacology, and lays a methodological foundation for modern development of medicinal and edible resources.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with hangover-alleviating and liver-protecting effects and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: semen hoveniae, flos puerariae, rhizoma gastrodiae, pericarpium citri reticulatae, poria cocos, rhizoma alismatis, herba artemisiae scopariae, gynostemma pentaphylla, roasted rhizoma atractylodis macrocephalae, cortex magnoliae officinalis, radix paeoniae alba and honey-fried licorice root. The traditional Chinese medicine composition disclosed by the invention has the effects of relieving alcoholism, resolving damp turbidity, clearing liver and gallbladder and strengthening spleen soil. The traditional Chinese medicine composition disclosed by the invention is particularly suitable for patients suffering from alcohol fever, alcoholic liver, hyperlipidemia and liver and gall diseases mainly caused by damp turbidity and alcohol toxicity. Experimental results show that the traditional Chinese medicine composition has a good treatment effect on acute alcoholic liver injury and chronic alcoholic fatty liver, so that the traditional Chinese medicine composition has a relatively good development and utilization prospect.

The invention discloses a traditional Chinese medicine composition for protecting the liver and soothing the nerves and a preparation method thereof. The traditional Chinese medicine composition comprises hovenia dulcis thunb decoction pieces, vinegar-processed kadsura longepedunculata decoction pieces, radix puerariae decoction pieces, parched white peony root decoction pieces, salvia miltiorrhiza decoction pieces, vinegar-processed bupleurum chinense decoction pieces, poria cocos decoction pieces and honey-fried licorice root decoction pieces. Aiming at the characteristics of effective components in hovenia dulcis thunb, kadsura longepedunculata processed with vinegar, the root of kudzu vine, parched white peony root, the root of red-rooted salvia, bupleurum chinense processed with vinegar, poria cocos and honey-fried licorice root and the traditional Chinese medicine theory, the traditional Chinese medicine composition is prepared by adopting the steps of water extraction, concentration and drying according to the traditional Chinese medicine process. The dry granulation maximally retains the effective components, increases the concentration of the effective components, improves the biological activity of the effective components and ensures the efficacy of the product, the dry granulation is adopted in the granulation process, wetting and heating are avoided, the effective components are not lost and are all retained, dextrin is adopted as a filler and an adhesive, and sugar components are not contained. The beverage can be used by normal people and people with abnormal glucose metabolism.

The invention discloses a hangover-alleviating and liver-protecting preparation, which belongs to the technical field of pharmacy and comprises a porous skeleton, a targeted nano core dispersed in pores of the porous skeleton and a conditioning layer, the porous framework is formed by taking sodium alginate, chitosan and pullulan as base materials, and an effervescing agent is uniformly dispersed in the porous framework and comprises organic acid and bicarbonate; the targeted nano core comprises an ionic cross-linked dual network formed by film-forming polysaccharide and gellan and is coated with an enteric layer; alcohol effect dispelling layer powder is further dispersed in the porous framework and comprises one or more of kudzuvine roots, hovenia dulcis thunb, turmeric extracts, taurine, emblic leafflower fruit extracts, corn oligopeptide powder, rice bran fatty alkanol, ammonium glycyrrhizinate and mung beans. The conditioning layer comprises one or two of resistant dextrin and soluble dietary fiber. The hangover-alleviating and liver-protecting preparation provided by the invention simultaneously realizes near-end intervention of controllable retention and quick release in the stomach, efficient and in-place liver-protecting release of the small intestine section and far-end support of continuous conditioning of the colon section.

The invention discloses a composition for dispelling effects of alcohol and protecting liver as well as a preparation method and application thereof. The composition is prepared from the following raw material medicines: 30-50 parts of oyster peptide, 50-100 parts of radix puerariae, 50-100 parts of hovenia dulcis thunb, 20-30 parts of chrysanthemum, 20-30 parts of endothelium corneum gigeriae galli, 20-30 parts of malt, 20-30 parts of pericarpium citri reticulatae, 20-30 parts of liquorice, 20-30 parts of fructus lycii, 10-20 parts of red dates, 10-20 parts of American ginseng and 10-20 parts of corn oligopeptide. Pharmacodynamic tests show that the composition can significantly reduce drunkenness time, improve activity of ethanol-related metabolic enzymes, reduce levels of serum ALT, AST and ALP induced by acute alcoholic liver injury, enhance expressions of various antioxidant systems in liver tissues, significantly inhibit secretion level of inflammatory factors in serum, and improve liver injury resistance. Meanwhile, hepatic lesions and fat deposition are relieved at a histological level, so that the composition disclosed by the invention has obvious functions of dispelling the effects of alcohol and protecting the liver through scientific proportioning and synergistic interaction of the raw materials.

The present application provides a kind of kudzu vine cranberry composition for protecting liver from alcohol, which contains the following ingredients by weight: 30-50 parts of extract of Hovenia dulcis Thunb, 30-50 parts of mixed extract, 20-40 parts of extract of Pueraria lobata, 10-20 parts of extract of Poria cocos, 10-20 parts of extract of Glycyrrhiza uralensis, 0.05-0.1 parts of vitamin C; the raw materials of the mixed extract are mixed by cranberry and Fructus Lycii in a mass ratio of (1-2):(1-2). The present application further provides formulations and food containing the composition. The present application further protects the use of the composition or formulation in preparing health food or medicine with auxiliary protective effect on chemical liver injury. The composition provided by the present application can improve the activity of alcohol dehydrogenase / acetaldehyde dehydrogenase, reduce the content of MDA in tissues and increase the content of GSH, and reduce the content of triglyceride in liver cells, thereby comprehensively exerting the effect of protecting liver from alcohol, with high safety, small side effects, and wide sources of raw materials, and having important market value and development prospect.

The application discloses a kind of American ginseng compound antioxidant products, is prepared from the following mass fraction components extraction: American ginseng 20-30 parts, 15-25 parts of radix rehmanniae preparata, 20-28 parts of dogwood, 15-25 parts of radix scrophulariae, 15-25 parts of gardenia, 8-12 parts of safflower, 18-22 parts of chuanxiong, 20-26 parts of citrus aurantium, 18-25 parts of alocasia, 10-20 parts of polygala, 16-26 parts of Platycladus branchlet, 15-25 parts of hovenia dulcis thunb, after screening, cleaning, crushing, weighing, alcohol extraction, water extraction, concentration and the like step is made.Compared with prior art, the application obtains the beneficial effect: synergistic effect between components, by tonifying qi and invigorating the spleen, nourishing liver and kidney, clearing heart and detoxifying, promoting blood circulation and qi movement, it has the effect of root and original for senile dementia, using reasonable extraction method is beneficial to the extraction of each effective component;Since the components of the application are non-toxic commonly used medicinal materials, there is no harm to the body after use, and there is no side effect.

The present invention belongs to the field of traditional Chinese medicine for treating liver diseases, and is particularly related to a composition having a protective function against chemical liver damage and a preparation method thereof. The raw materials of the composition are composed of the following components in parts by weight: 8-15 parts of kudzu root, 3-10 parts of hovenia dulcis, 3-12 parts of schisandra chinensis, 2-9 parts of ginseng and 2-10 parts of shiitake mushroom. The preparation method comprises: first extracting volatile oil from ginseng, shiitake mushroom and schisandra chinensis, enzymolyzing the filtrate, mixing the medicinal residues with kudzu root and hovenia dulcis to extract weak polar active ingredients, then extracting the active ingredients with water through a macroporous resin, and finally concentrating and drying the extracts to obtain a dry paste powder. The preparation method of the present invention has a high utilization rate of medicinal materials, and the obtained composition has a precise protective effect on chemical liver damage, is safe to take, and has controllable quality.

This invention discloses a method for improving the fruit set rate of Hovenia dulcis, belonging to the field of agricultural production technology. Addressing the low fruit set rate caused by anther abortion, insufficient pollinating insects, and self-incompatibility, this invention comprehensively applies three synergistic measures: First, spraying a hormone solution of GA 35 μg / g and IAA 3 μg / g during the bud stage promotes pollen and style development; second, attracting native bees by planting motherwort and white clover, and leasing and introducing Italian bee colonies during peak flowering to enhance natural pollination; finally, preparing and spraying an artificial pollination solution containing specific concentrations of sucrose, boric acid, and calcium ions during the flowering period for assisted pollination. This method systematically solves the bottlenecks in each stage of pollination, increasing the fruit set rate of Hovenia dulcis from a natural 12.67% to a maximum of 71.24%, resulting in a significant yield increase and wide applicability to the development of the Hovenia dulcis industry.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a medicinal and edible composition with effects of dispelling effects of alcohol and protecting liver as well as a preparation method and application of the medicinal and edible composition. The composition is prepared from the following raw materials in parts by weight: 45 to 50 parts of radix puerariae, 28 to 33 parts of semen hoveniae and 10 to 15 parts of flos lonicerae. The preparation method comprises the following steps: performing water extraction, concentration and drying on raw materials to obtain an extract A; or centrifuging, dialyzing and filtering the concentrated solution, and drying to obtain an extract B; according to the invention, three medicinal and edible substances are compatible according to an optimal ratio (50 of radix puerariae, 30 of hovenia dulcis thunb and 12 of honeysuckle), the blood ethanol concentration is synchronously reduced, the liver injury is repaired, and the gastric inflammation is inhibited, the equivalent efficacy of the extract A (1.12 g / kg) is realized by the extract B at the dosage of 0.12 g / kg, and the burden of the liver and the kidney is reduced. The traditional Chinese medicine composition is suitable for development of anti-alcoholism medicines, liver-protecting functional foods and beverages, and the equivalent weight of crude drugs per day is 5-15g.

The invention relates to the technical field of traditional Chinese medicine preparations, and discloses a preparation method of a liver-protecting and hangover-alleviating formula containing radix puerariae, turmeric, hovenia dulcis thunb and penthorum chinense pursh, and the liver-protecting and hangover-alleviating formula is prepared from the following raw materials in parts by weight: 20-40 parts of radix puerariae, 15-30 parts of turmeric, 10-25 parts of hovenia dulcis thunb and 10-25 parts of penthorum chinense pursh. According to the preparation method of the liver-protecting and hangover-alleviating radix puerariae, turmeric, hovenia dulcis thunb and penthorum chinense pursh, based on the theory of traditional Chinese medicine and modern pharmacological research, radix puerariae, turmeric, hovenia dulcis thunb and penthorum chinense pursh are scientifically matched, and radix puerariae has the effects of resisting oxidation and promoting alcohol metabolism; turmeric is anti-inflammatory and anti-oxidative stress; hovenia dulcis thunb inhibits alcohol absorption and protects liver cell membranes; penthorum chinense pursh has the effects of detoxifying, resisting inflammation and protecting the liver, the four medicines are combined to achieve a multi-target and multi-path synergistic effect, the powerful effects of protecting the liver and relieving alcoholism are jointly achieved, and the effect is better than that of a single medicinal material or a simple combination.

This invention provides a traditional Chinese medicine preparation for treating or relieving functional constipation in children, belonging to the field of traditional Chinese medicine technology. The preparation is made from raw Atractylodes macrocephala, banana root, Citrus reticulata, mulberry, Lophatherum gracile, Hovenia dulcis leaf, Ziziphus jujuba leaf, Pogostemon cablin, Citrus reticulata peel, Torreya grandis seed, and licorice. This traditional Chinese medicine preparation significantly increases the number of fecal particles in constipation model rats over 24 hours, increases fecal water content, and improves intestinal propulsion rate, thus improving intestinal peristalsis. In clinical observation, this traditional Chinese medicine preparation effectively relieves the core symptoms of children, shortens the interval between defecation, softens stool, and alleviates straining during defecation. It also improves accompanying symptoms such as abdominal distension and halitosis. After the course of treatment, bowel regularity returns, and there is no significant recurrence during follow-up, providing a new option for the clinical treatment of functional constipation in children.

The invention discloses a medicinal and edible biological preparation for dispelling effects of alcohol and protecting liver as well as a preparation method and application of the medicinal and edible biological preparation. The medicinal and edible biological preparation is prepared from the following raw materials in parts by weight: 10 to 15 parts of radix puerariae, 5 to 15 parts of semen hoveniae, 2 to 10 parts of liquorice root, 10 to 15 parts of poria cocos, 6 to 15 parts of honeysuckle flower and 5 to 15 parts of curcumin. After the six extracts are compounded, an excellent hangover alleviating effect is achieved, alcohol metabolism can be accelerated, and the hangover alleviating time can be shortened. Wherein the kudzuvine root, the hovenia dulcis thunb, the poria cocos, the liquorice and the honeysuckle have the effects of protecting liver and benefiting gallbladder, and can inhibit liver injury and promote regeneration of hepatocytes; the turmeric has the effects of dispelling the effects of alcohol, preventing hangover and the like. The composition disclosed by the invention is used as a main active component of the beverage for dispelling effects of alcohol and protecting liver, and has good taste and rich nutritional value. In addition, the influence of the curcumin freeze-dried powder on the activity of ADH and SOD is adjusted under a specific pH value, so that the alcohol effect dispelling effect is optimal.

The present invention relates to a composition for preventing, ameliorating or treating benign prostatic hyperplasia, containing a Hovenia dulcis extract as an active ingredient. Specifically, the Hovenia dulcis extract of the present invention was confirmed to inhibit the proliferation of hyperproliferative prostatic cells induced by dihydrotestosterone (DHT), which is a male hormone, and reduce prostate weight in an animal model with induced benign prostatic hyperplasia, and thus can be effectively used as a composition for preventing, ameliorating or treating benign prostatic hyperplasia.

The present invention relates to: a method for preparing a Hovenia dulcis Thunb fruit fermented vinegar having hangover relief and liver protection effects; and a beverage composition prepared using the same as a main ingredient. In the method for preparing fermented vinegar by using Hovenia dulcis Thunb fruits of the present invention, a Hovenia dulcis Thunb fruits concentrate is made using Hovenia dulcis Thunb fruits and is adjusted to 16 °Brix. 10% (v / v) seed mash is inoculated thereto and subjected to alcohol fermentation at a temperature of 28 to 32 °C. Then obtained alcoholic fermentation filtrate is used as a substrate of acetic acid fermentation. In the acetic acid fermentation, a fermented liquid obtained through alcoholic fermentation of Hovenia dulcis Thunb fruits is inoculated with 10% (v / v) of a vinegar starter, and then fermented at a temperature of 28 to 32 °C under a 120 to 180 rpm condition.

The invention belongs to the field of life health and health products, and discloses a preparation method and application of medicinal and edible oral liquid with effects of dispelling effects of alcohol and protecting liver. The raw material formula comprises a ginseng extract, hovenia dulcis thunb, radix puerariae, roselle, rhizoma polygonati, gastrodia elata, schisandra chinensis and a dihydroquercetin extract, the hovenia dulcis thunb, the radix puerariae, the roselle, the rhizoma polygonati, the gastrodia elata and the schisandra chinensis are taken in proportion, water reflux extraction and filtration are performed, extracting solutions are combined, the ginseng extract and the dihydroquercetin extract are added, and filling and sterilization are performed to obtain the traditional Chinese medicine composition. Functions of the raw materials are fully utilized, the oral liquid is capable of relieving drunkenness, enlivening spleen, protecting liver and benefiting gallbladder, and behavioral observation of a mouse acute alcoholism experiment proves that the oral liquid can delay drunkenness, accelerate sobering up and relieve swelling pain of brain and liver, drunkenness and the like caused by excessive drinking. Enzymatic index detection of a mouse acute alcoholism experiment proves that the oral liquid can quickly improve the alcohol decomposition capability of the liver after being taken, delay the absorption of alcohol in the body and achieve the effects of dispelling the effects of alcohol and relieving drunkenness.

The invention belongs to the technical field of traditional Chinese medicine, and provides traditional Chinese medicine freeze-dried powder for dispelling effects of alcohol and protecting liver and a preparation method thereof. The mass ratio of the freeze-dried powder of radix puerariae to the freeze-dried powder of semen hoveniae to the freeze-dried powder of schisandra chinensis is (0.8-1.2): (0.8-1.2): (0.8-1.2) The radix puerariae promotes alcohol metabolism, the hovenia dulcis thunb relieves alcohol toxicity, the schisandra chinensis protects the liver, the synergistic effect of the three traditional Chinese medicinal materials is fully played, the alcohol effect relieving and liver protecting effects are enhanced, the freeze drying technology is adopted, drying is completed under the low-temperature condition, damage of high temperature to active ingredients is avoided, and the stability of the product in the storage process is remarkably improved; the freeze-dried powder exists in a fine particle state, so that the contact surface area with a human body is increased, the release and absorption of effective components are facilitated, and the bioavailability is improved.

The invention relates to liver-protecting konjac, radix puerariae and semen hoveniae granules and a production control method, and belongs to the technical field of food processing and medicines.The production control method comprises the steps that active ingredients are extracted in a graded mode through a multi-stage separation device, and an initial functional ingredient set is generated; optimizing the raw material proportion by adopting a dynamic proportion algorithm to generate an optimized formula; carrying out ultrasonic-assisted extraction and low-temperature vacuum concentration technology treatment to generate a high-purity functional extract; generating a particle primary product by using a fluidized bed granulation technology, and detecting the content of functional components on line by using a near infrared spectrum analysis technology; a feedback control algorithm is adopted to adjust granulation process parameters, and an optimized path is generated; the components are verified through a gas chromatography-mass spectrometry technology, and a verification report is generated; and recording the key data based on the distributed storage system, and generating a complete production control file. According to the method, efficient extraction, stable production and accurate quality control can be realized, and the product consistency and the market competitiveness are remarkably improved.

The application provides a composition for assisting in protecting chemical liver injury and a preparation method and application thereof, and relates to the technical field of medicines.The composition for assisting in protecting chemical liver injury provided by the application has the following raw material components: radix puerariae, ganoderma lucidum, hovenia dulcis thunb, schisandra chinensis, curcuma longa, dioscorea, glycyrrhiza uralensis, fructus jujubae, taraxacum mongolicum, chrysanthemum, polygonatum and pericarpium citri reticulatae.The components are extracted by decocting with water, the extraction liquid is mixed and dried, and the obtained composition has the function of assisting in protecting chemical liver injury, and is applied to products with the functions of improving damaged liver cells, reducing transaminase, reducing blood lipids and improving the shape of the liver, and the effect is remarkable.The composition can effectively improve the chemical liver injury of model mice in the dosage range of the components, and has similar efficacy compared with silymarin which is a clinically applied drug.

The invention relates to the technical field of food and / or medicine, and provides application of a traditional Chinese medicine composition in preparation of food, health food and / or medicine for relieving or improving sub-health caused by staying up late, the composition is prepared from the following raw materials in parts by weight: 100-500 parts of centella asiatica, 200-600 parts of pachyrhizua angulatus, 100-500 parts of hovenia dulcis thunb, 100-500 parts of lalang grass rhizome, 100-500 parts of hawthorn and 100-300 parts of chrysanthemum. The composition provided by the invention can relieve or improve sub-health states such as biological clock rhythm disorder and memory function decline caused by staying up late, reduces harm and injury after staying up late, meets new requirements of people for health, is beneficial to improving the life quality of people, and has a good market prospect.

The present invention relates to the technical field of traditional Chinese medicines, and more particularly, to a liver-protecting composition and a method for producing the same. The liver-protecting composition contains, by weight, 10 to 25 parts of plantain, 5 to 15 parts of licorice, 5 to 13 parts of turmeric, 2 to 8 parts of ginseng, 2 to 8 parts of Hovenia dulcis Thunb., and a flavoring agent, wherein the flavoring agent contains autumn pear. The present invention relates to a pure traditional Chinese medicine that is easy to produce, convenient to take, has good effects of protecting and nourishing the liver, and also has an effect of mitigating the effects of alcohol.