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40 results about "Chronic alcoholic" patented technology
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A chronic alcoholic is a person who is severely addicted to and dependent on alcohol. They will consume alcohol every day at dangerously high levels.
Anthropogenic lactobacilus fermentum grx07 and application thereof
ActiveCN103937716AProtectiveImprove protectionMilk preparationBacteriaLactobacillus fermentumApoptosis
The invention relates to anthropogenic lactobacilus fermentum grx07 with a protection role on chronic alcoholic liver damage and application thereof. The lactobacilus fermentum grx07 strain disclosed by the invention is a probiotic strain separated from intestinal tracts of people in a Rugao longevity village of Jiangsu, the strain is preserved in China General Microbiological Culture Collection Center, and the preservation number is CGMCC No.8874. The lactobacilus fermentum grx07 strain has significant in vitro antioxidant ability and pathogenic bacteria inhibition ability, the rat blood fat of chronic alcoholic liver damage and the toxin level in serum can be significantly reduced, expression of liver inflammatory cytokines is reduced, the inflammatory reaction of the liver is relieved, the expression quality of antioxidant specific protein Nrf2 of the liver is increased, and the liver cell apoptosis percentage is reduced. Therefore, the anthropogenic lactobacilus fermentum grx07 has a significant protective effect on the chronic alcoholic liver damage.
Owner:YANGZHOU YANGDA KANGYUAN DAIRY
The protective effects and application of a Lactobacillus rhamnosus on the alleviation of chronic alcoholic liver injury
An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.
Owner:JIANGNAN UNIV
Protective effects and application of a lactobacillus rhamnosus on the alleviation of chronic alcoholic liver injury
ActiveUS20160113975A1Improve antioxidant capacityLow rateBiocideMilk preparationDPPHLactobacillus rhamnosus
An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.
Owner:JIANGNAN UNIV
Application of lactobacillus casei grx12 in preparation of product for treating chronic alcoholic liver injury
InactiveCN103893215AReduce inflammationReduce blood lipids in ratsMilk preparationBacteria material medical ingredientsInflammatory factorsBacteroides dorei
The invention relates to an application of anthropogenic lactobacillus casei grx12 in the aspect of chronic alcoholic liver injury. The lactobacillus casei grx12 is a probiotic strain with an obvious in-vitro antioxidant capacity, which is obtained in a separation mode from the intestinal tracts of people in the long life village of Rugao city, Jiangsu province. The lactobacillus casei grx12 is preserved in China General Microbiological Culture Collection Center (CGMCC) of China Committee for Culture Collection of Microorganisms (CCCCM) and has the preservation number of CGMCC No.7696. The lactobacillus casei grx12 can be used for obviously decreasing the level of toxins in blood fat and blood serum of a rat with the alcoholic liver injury, decreasing the expression of liver inflammatory factors in the liver and relieving the inflammatory reaction of the liver, thereby having obvious protection functions to the chronic alcoholic liver injury.
Owner:YANGZHOU UNIV
Composition capable of timely preventing alcoholism and protecting stomach, liver and brain and application thereof
InactiveCN106235327APromote absorptionTo promote metabolismFood ingredient functionsAlcoholismsFood grade
The invention relates to a composition capable of timely preventing alcoholism and protecting the stomach, the liver and the brain and application thereof. The composition is prepared from taurine, kudzuvine roots, semen hoveniae, gamma-aminobutyric acid, sodium alginate and fructo-oligosaccharide. The composition can be prepared into different forms of healthcare food and nutrient fortification food and is suitable for timely preventing alcoholism and protecting the stomach, the liver and the brain for a drinker and suitable for adjuvant therapy of injures such as chronic alcoholic livers and brains; in addition, the raw materials are food-grade raw materials, and therefore the advantages of being natural and safe are achieved.
Owner:万光瑞
Traditional Chinese medicine extract mixed preparation and application thereof
InactiveCN102114102ADegree of reductionDigestive systemPlant ingredientsBile duct ligationBaical Skullcap Root
The invention discloses a traditional Chinese medicine extract mixed preparation which comprises a baical skullcap root extract, a cape jasmine fruit extract and an Indian buead extract, wherein the mixture ratio of the three is (80-100): (80-100): (100-150); and the content of scutelloside in the baical skullcap root extract is above 90%, the content of geniposide in the cape jasmine fruit extract is above 90%, and the content of polysaccharides in the Indian buead extract is above 50%. The traditional Chinese medicine extract mixed preparation has the effects of protecting liver and benefiting gallbladder, and can be used for preparing medicaments or health care products for protecting the liver and benefiting the gallbladder, or the medicaments for treating obstructive jaundice, or the medicament for treating cholestasis, or the medicaments for treating chronic alcoholic liver injury. The effects of the traditional Chinese medicine extract mixed preparation for and benefiting the gallbladder and protecting the cholestasis of rats caused by bile duct ligation and ANIT (alpha-naphthylisothiocyanate) and the alcoholic liver injury of the rats are obviously better than conventional control medicaments, and the liver injury degree and the icterus index can be significantly reduced.
Owner:SHANDONG ACAD OF CHINESE MEDICINE
Lactic acid bacteria formula for preventing acute and chronic alcoholic liver injury and application thereof
ActiveCN111437294AGood simulated gastrointestinal fluid toleranceInhibit inflammationDigestive systemUnknown materialsLactobacillus acidophilusFatty acid
The invention discloses a lactic acid bacteria formula for preventing acute and chronic alcoholic liver injury and application thereof. Lactobacillus plantarum KLDS1.0344 and lactobacillus acidophilusKLDS1.0901 have good gastrointestinal fluid tolerance simulating capacity, have certain adhesion capacity to HT-29 cells and have basic probiotic characteristics; the lactobacillus plantarum KLDS1.0344 and the lactobacillus acidophilus KLDS1.0901 can prevent acute alcoholic liver injury; and the lactobacillus plantarum KLDS1.0344 and the lactobacillus acidophilus KLDS1.0901 can prevent chronic alcoholic liver injury. Specifically, the lactobacillus plantarum KLDS1.0344 and the lactobacillus acidophilus KLDS1.0901 have the functions of reducing the liver index, improving the intestinal barrier, improving the liver function, reducing the inflammation level in the liver, increasing the content of short-chain fatty acid in the intestinal tract, reducing protein expression of CYP2E1 in the liver and the like.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY
Ginseng and bamboo leaf composition capable of preventing and treating alcoholic liver injuries
InactiveCN105878803AReduce concentrationEasy to removeDigestive systemFood ingredient functionsNonalcoholic fatty liver diseaseAmpelopsis
The invention relates to a natural medicine composition capable of preventing and treating alcoholic liver injuries. The composition is prepared from total saponins of ginsengs, total flavonoids of ampelopsis grmsedntara leaves, total flavonoids of bamboo leaves and isodon lophanthoides var.gerardianus extract. The invention further relates to application of the composition to preparation of health foods capable of preventing and treating acute and chronic alcoholic liver injuries and preparation of health foods, beverages and tea capable of preventing and treating non-alcohol fatty liver. All the components of the composition have good synergistic effect and remarkable curative effect; raw materials are easily obtained, the cost is relatively low and the practicability is relatively strong.
Owner:JILIN CHANGBAI MINGZHU FOREST FOOD CO LTD
New use of globe artichoke stem-leaf extract
The invention discloses new use of a globe artichoke stem-leaf extract. The globe artichoke stem-leaf extract has the efficacies of resisting inflammation and preventing and treating chronic alcoholic liver injury and non-alcoholic fatty liver disease by decreasing the expression quantity of TLR4, NF-kappaB, IL-1beta, IL-6 and IL-8. The globe artichoke stem-leaf extract disclosed by the invention can play roles of multiple effects, multiple target points and multiple functions. Compared with existing oral alcohol-dispelling liver-protecting drugs, the globe artichoke stem-leaf extract has the advantages that the safety is relatively high; the globe artichoke stem-leaf extract is convenient to prepare and wide in market application prospects, can be applied to the preparation of medicines, health foods, food additives, feed additives, antioxidants and the like and has wide application prospects and huge economic benefits in the fields of processing and application.
Owner:HUAQIAO UNIVERSITY
Chinese medicinal composition for treating chronic alcoholic toxic liver disease
ActiveCN103830337AFully functionalGood treatment effectDigestive systemAntineoplastic agentsToxic liver diseaseStephania
The invention belongs to the technical field of medicine, and relates to a Chinese medicinal composition, in particular to a Chinese medicinal composition for treating chronic alcoholic toxic liver disease and a preparation method thereof. Aiming at the current technological defects that the chronic alcoholic toxic liver disease cannot be treated comprehensively and effectively and chemical treatment has the defects of high relapse rate and discontinuous curative effect, the Chinese medicinal composition for treating or preventing the chronic alcoholic liver toxic disease comprises the following components in parts by weight: 10 parts of corydalis tuber, 15 parts of fourstamen stephania root, 6 parts of virgate wormwood herb, 10 parts of glossy privet fruit, 10 parts of Szechuan lovage rhizome, 6 parts of Chinese angelica, 20 parts of sophora flower, 20 parts of tribulus terrestris, 10 parts of Chinese thorowax root, 12 parts of baikal skullcap root, 15 parts of baikal skullcap root, 30 parts of cassia twig, 6 parts of Indian buead and 10 parts of liquoric root. The Chinese medicinal composition has a very good treatment effect on the chronic alcoholic toxic liver disease, and has a remarkable clinical popularization value.
Owner:吴琼
Application of methyl ferulic acid in preparation of medicine for preventing and treating alcoholic liver disease
InactiveCN105582003AExact therapeutic effectLower levelOrganic active ingredientsDigestive systemMedicineCell damage
The invention discloses an application of methyl ferulic acid in preparation of a medicine for preventing and treating alcoholic liver disease. An ethanol induced L-02 cell damage model proves that the methyl ferulic acid can reduce the MDA level and improve the activity of SOD, GSH-Px and CAT. According to animal experiments, the methyl ferulic acid can remarkably reduce the contents of ALT, AST and MDA of the rat suffering acute alcoholic liver injury and obviously improve the activity of SOD, GSH-Px and CAT; and the methyl ferulic acid can obviously reduce the content of triglyceride (TG), ALT, AST and MDA of the rat suffering chronic alcoholic liver injury and noticeably improve the activity of SOD, GSH-Px and CAT. The results of the cell and animal experiments indicate that the methyl ferulic acid has an exact effect in preventing and treating alcoholic liver disease and can be used for preparing a medicine for preventing and treating alcoholic liver disease independently or in combination.
Owner:GUILIN MEDICAL UNIVERSITY
Drug for relieving body injury caused by chronic alcoholic poisoning
ActiveCN108324704AImprove intelligenceProtective functionOrganic active ingredientsAntinoxious agentsAminohydroxyacetic acidAdditive ingredient
The invention provides a drug for relieving body injury caused by chronic alcoholic poisoning. The drug comprises an effective ingredient of AOAA (aminooxyacetic acid). Learning and memory ability evaluation is performed on chronic alcoholic poisoned rats and normal rats by use of a Y-type electric maze by establishing a rate chronic alcoholic poisoning model. Experimental results prove that compared with normal control groups, the chronic alcoholic poisoning model group of rats has remarkably reduced learning and memory ability. After AOAA intervention is given, the training times required for rats of a remedy group to learn spatial discrimination are reduced, and difference has statistical significance. Accordingly, AOAA can relieve memory deterioration caused by the chronic alcoholic poisoned rats, improves the learning memory ability and provides a scientific basis for research of chronic alcoholic poisoning injury mechanism and treatment by AOAA.
Owner:XINXIANG MEDICAL UNIV
Novel natural herbal compound composition with sobering and liver protection effects and application thereof
InactiveCN102416086AGood synergySignificantly sober upDigestive systemAntinoxious agentsVitamin E AcetateVitamin B12
The invention discloses a novel natural herbal compound composition with sobering and liver protecting effects and preparation as well as application thereof. The composition is prepared from active ingredients which mainly have the sobering and liver protecting effects and auxiliary materials, wherein the composition of the active ingredients comprise the following components in percentage by weight based on total weight of the active ingredients: 3-10 percent of sesamin, 0.05-5 percent of schisandrin, 10-45 percent of hovenia dulcis thumb extract, 10-45 percent of kudzu vine flower extract, 10-45 percent of nutgrass galingale rhizome extract, 0-0.02 percent of vitamin B12 and 1-10 percent of vitamin E acetate. The invention also relates to application of the composition to preparation of health care foods for preventing and / or treating acute alcoholism, health care foods for treating chronic alcoholic liver damage and health care foods for treating nonalcoholic fatty liver. The composition has the advantages of good synergistic reaction among the components, obvious curative effect, readily available raw materials, easiness in preparation and relatively low cost.
Owner:中哈福生物医药科技(上海)有限公司
Active peptide with effect of preventing chronic alcoholic liver injury
ActiveCN112979748AElevated ALT activityIncrease vitalityMetabolism disorderDigestive systemLiver tissueChronic alcoholic
The invention discloses an active peptide with an effect of preventing chronic alcoholic liver injury. The amino acid sequence of the active peptide is Gly-Thr-Tyr-Trp (GTYW). According to the invention, in the chronic alcoholic liver injury animal model experiment, the active peptide can significantly reduce the mouse serum AST and ALT activity and the liver / serum TG content and significantly increase the mouse liver AST and ALT activity, and the liver tissue injury caused by ethanol is gradually improved through the pathological section, so that it is indicated that the GTYW has the effect of preventing the chronic alcoholic liver injury. According to the active peptide, not only can the economic added value of soybean meal be increased, but also a new thought for development and utilization of liver protection products is provided.
Owner:JILIN UNIV
Application of traditional Chinese medicine composition in preparing medicine capable of treating chronic alcoholic steatohepatitis
ActiveCN110742935ASignificant effectAnthropod material medical ingredientsDigestive systemAlcohol ethylCurative effect
The invention relates to application of a traditional Chinese medicine composition in preparing a medicine capable of treating chronic alcoholic steatohepatitis. The traditional Chinese medicine composition is prepared from the following ingredients in parts by weight: 5-15 parts of radix rhei, 5-15 parts of semen persicae and 3-9 parts of eupolyphaga seu steleophaga. The traditional Chinese medicine composition is prepared according to the following method: independently smashing all raw materials, independently extracting by ethyl alcohol of which the volume concentration is 10-30% for 1-3 times, collecting and combining extracting solutions, and recovering the ethyl alcohol to obtain the traditional Chinese medicine composition. A decoction for discharging blood clots is used for treating the chronic alcoholic steatohepatitis, a good curative effect is obtained, the application range of the decoction for discharging blood clots is enlarged, and a new thought and a new method are provided for clinically treating the chronic alcoholic steatohepatitis.
Owner:SHANGHAI PUTUO DISTRICT CENT HOSPITAL
A kind of ganoderma lucidum crabapple tea and its preparation process and application
ActiveCN104839382BEnhanced inhibitory effectSimple preparation processDigestive systemTea substituesBlood sugarSynergy
The invention relates to a Ganoderma lucidum crabapple tea and a preparation method thereof. The Ganoderma lucidum crabapple tea is made of Ganoderma lucidum powdered Begonia tea in bag, Ganoderma lucidum spore powdered Begonia tea in bag or Ganoderma lucidum fermented Begonia tea in bag. The ganoderma lucidum crabapple tea is a health product, and the invention applies the crabapple tea to the preparation, treatment or prevention of liver cell damage in vitro, chronic alcoholic liver cell damage, breast cancer, and lowering blood fat and blood sugar. The preparation process of the invention is simple, the material is easy to obtain, and the application in health tea is considerable. The health tea has a better synergistic effect on CCL4-induced liver cell injury. At the same time, the health tea has obvious inhibitory effect on ALT in the serum of mice with chronic alcoholic liver injury, showing a better synergistic effect. Can be widely promoted.
Owner:恩施硒海棠生物科技有限公司
Composition capable of protecting liver with chronic alcoholic liver damage and preparation method of composition
InactiveCN105362316AExploitationGood effectOrganic active ingredientsAntipyreticCordycepsFluidized bed
The invention discloses a composition capable of protecting the liver with chronic alcoholic liver damage. The composition comprises, by weight, 1-5 parts of Penthorum chinense Pursh extract, 0.5-1 part of oligochitosan, 1-2 parts of cordyceps polysaccharide and 1-2 parts of dextrin. A preparation method of the composition includes: separating the Penthorum chinense Pursh extract through macroporous resin, respectively using 1% sodium hydroxide and 95% ethanol for extracting, concentrating, then absorbing with the macroporous resin, respectively using deionized water, 20% ethanol and 40% ethanol to wash impurities absorbed in the resin, eluting with 80% ethanol, and then performing vacuum concentrating; mixing the Penthorum chinense Pursh extract concentrated solution with the oligochitosan, cordyceps polysaccharide and dextrin according to the weight to obtain slurry, spray drying to prepare into powder, using a fluidized bed method to prepare into particles, and drying to obtain granules. The granules can protect the liver of a rat with the chronic alcoholic liver damage.
Owner:BEIJING UNION UNIVERSITY
Protective effects and application of a Lactobacillus rhamnosus on the alleviation of chronic alcoholic liver injury
Owner:JIANGNAN UNIV
Chinese medicinal composition for treating chronic alcoholic toxic liver disease
ActiveCN103830337BFully functionalGood treatment effectDigestive systemAntineoplastic agentsToxic liver diseaseStephania
The invention belongs to the technical field of medicine, and relates to a Chinese medicinal composition, in particular to a Chinese medicinal composition for treating chronic alcoholic toxic liver disease and a preparation method thereof. Aiming at the current technological defects that the chronic alcoholic toxic liver disease cannot be treated comprehensively and effectively and chemical treatment has the defects of high relapse rate and discontinuous curative effect, the Chinese medicinal composition for treating or preventing the chronic alcoholic liver toxic disease comprises the following components in parts by weight: 10 parts of corydalis tuber, 15 parts of fourstamen stephania root, 6 parts of virgate wormwood herb, 10 parts of glossy privet fruit, 10 parts of Szechuan lovage rhizome, 6 parts of Chinese angelica, 20 parts of sophora flower, 20 parts of tribulus terrestris, 10 parts of Chinese thorowax root, 12 parts of baikal skullcap root, 15 parts of baikal skullcap root, 30 parts of cassia twig, 6 parts of Indian buead and 10 parts of liquoric root. The Chinese medicinal composition has a very good treatment effect on the chronic alcoholic toxic liver disease, and has a remarkable clinical popularization value.
Owner:吴琼
A kind of natural medicinal composition for preventing and treating alcoholic liver injury and preparation method thereof
The invention relates to a natural medicine composition for relieving alcohol and protecting the liver. The composition is composed of total triterpene acids of loquat leaves, total flavonoids of loquat leaves, total flavonoids of japonica grape and corn silk extract. The invention also relates to the application of the composition in preparing health food for preventing and treating acute and chronic alcoholic liver injury and in preparing health food or beverage for treating non-alcoholic fatty liver. The various components of the composition of the invention produce good synergistic effects, have remarkable curative effect, and the raw materials are easy to obtain, the cost is relatively low, and the composition has strong practicability.
Owner:JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT
Chinese and chemical medicine composition for treatment of alcoholism and preparation thereof
InactiveCN1439409ALow costEasy to produceNervous disorderUnknown materialsAlcoholismsChemical composition
A medicine in the form of oral liquid, instant particles, tablet, or capsule for treating acute or chronic alcoholic liver damage contains bitter pattra fruit, pueraria flower, VB6, ginsenoside, active substance and one or more medicinal carrier. It is prepared through crushing bitter pattra fruit and pueraria flower, mixing, immersing in water, heating for 30-60 min, filtering, decocting the dregs, filtering, collecting filtrate, concentrating, vacuum drying, and mixing with VB6 and ginsenoside.
Owner:SHENYANG PHARMA UNIVERSITY
Traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease
ActiveCN103705731AFully functionalGood treatment effectAnthropod material medical ingredientsDigestive systemToxic liver diseaseChemical treatment
The invention belongs to the technical field of medicine, relates to a traditional Chinese medicine composition, and in particular relates to a traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease and a preparation method thereof. Aiming at the current technical defects of lack of comprehensive and effective treatment on the chronic alcoholic toxic liver disease, easiness in relapse of chemical treatment, and inconstant curative effect, the invention provides the traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease. The traditional Chinese medicine composition comprises the following components: 10 parts of rhizoma alismatis, 15 parts of Fourstamen Stephania root, 6 parts of herba artemisiae, 10 parts of fleece-flower root, 10 parts of rhizoma ligustici wallichii, 6 parts of angelica, 20 parts of hovenia dulcis, 20 parts of Chinese gall, 10 parts of radix bupleuri, 12 parts of rhizoma polygonati, 15 parts of Scutellaria baicalensis, 30 parts of Lycium barbarum L., 6 parts of Poria cocos, and 10 parts of liquorice. The traditional Chinese medicine composition has a very good treatment effect in the treatment of chronic alcoholic toxic liver disease, and has significant clinical promotion value.
Owner:NANTONG FINC PHARMA CHEM
Ethanol Enhances the Complete Replication of Hepatitis C Virus: the Role of Acetaldehyde
InactiveUS20100226888A1Easy to removeBiocideSsRNA viruses positive-senseHMG-CoA reductaseFatty acid biosynthesis
Methods are provided for inhibiting replication of an RNA virus in a cell infected with the virus, wherein the cell is characterized as having been or concurrently being exposed to a physiologically relevant concentration of a compound selected from ethanol, acetate, isopropanol, acetaldehyde or acetone, comprising contacting the cell with an effective amount of one or more of a HMG-CoA reductase inhibitor, a fatty acid biosynthesis inhibitor, thyroxine, or an agent promoting clearance of the compound from a cell. Also provided are methods to treat a subject having one or more cells characterized as having a physiological concentration of ethanol, acetate, isopropanol, acetaldehyde or acetone, in particular subjects that suffer chronic alcoholics, diabetes or starvation.
Owner:RGT UNIV OF CALIFORNIA
A traditional Chinese medicine composition for treating chronic alcoholic liver disease
ActiveCN103705731BFully functionalGood treatment effectAnthropod material medical ingredientsDigestive systemToxic liver diseaseChemical treatment
The invention belongs to the technical field of medicine, relates to a traditional Chinese medicine composition, and in particular relates to a traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease and a preparation method thereof. Aiming at the current technical defects of lack of comprehensive and effective treatment on the chronic alcoholic toxic liver disease, easiness in relapse of chemical treatment, and inconstant curative effect, the invention provides the traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease. The traditional Chinese medicine composition comprises the following components: 10 parts of rhizoma alismatis, 15 parts of Fourstamen Stephania root, 6 parts of herba artemisiae, 10 parts of fleece-flower root, 10 parts of rhizoma ligustici wallichii, 6 parts of angelica, 20 parts of hovenia dulcis, 20 parts of Chinese gall, 10 parts of radix bupleuri, 12 parts of rhizoma polygonati, 15 parts of Scutellaria baicalensis, 30 parts of Lycium barbarum L., 6 parts of Poria cocos, and 10 parts of liquorice. The traditional Chinese medicine composition has a very good treatment effect in the treatment of chronic alcoholic toxic liver disease, and has significant clinical promotion value.
Owner:NANTONG FINC PHARMA CHEM
Application of ginsenoside Rc in preparation of medicine for treating alcoholic fatty liver
PendingCN114533749AAvoid damageInhibits oxidative stressOrganic active ingredientsDigestive systemGinsenoside RcOxidative stress
The invention provides application of ginsenoside Rc in preparation of a medicine for treating alcoholic fatty liver. Researches show that ginsenoside Rc can effectively inhibit liver injury, lipid accumulation, oxidative stress reaction and inflammatory reaction, so that acute / chronic alcoholic fatty liver is effectively treated, and a new material source is provided for the medicine for treating the alcoholic fatty liver.
Owner:GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
Application of total triterpenoids of Pteridocarpus in protecting chronic alcoholic liver injury
ActiveCN104922168BDamage reliefStrengthen the body's antioxidant capacityDigestive systemAntinoxious agentsPositive controlHigh doses
Owner:SHAANXI NORMAL UNIV
A kind of traditional Chinese medicine composition for relieving drunkenness and its application
ActiveCN106389999BAppropriate compatibilityExact therapeutic effectDigestive systemAntinoxious agentsBiologyChinese herbology
The invention relates to a traditional Chinese medicine composition for removing drunkenness and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from, by weight, 10-20 parts of flos puerariae or radix puerariae, 5-12 parts of rhizoma cyperi, 3-9 parts of fructus amomi and 5-12 parts of red dates, wherein the fructus amomi is decocted later. The traditional Chinese medicine composition is proper in compatibility, less in medicine and specific in effect, capable of effectively reducing damage of chronic alcoholic liver on AST (glutamic oxalacetic transaminase), ALT (alanine aminotransferase) and ALP (alkaline phosphatase) of mouse liver and ADH (antidiuretic hormone) of stomach and definite in effect of drunkenness preventing and treating; the pure traditional Chinese medicine preparation is free from toxic and side effects, good in safety and prone to acceptance of patients; meanwhile, the traditional Chinese medicine composition is few in number of medicine, low in cost and convenient in preparation.
Owner:徐建
Application of matteuccia struthiopteris total triterpenes to protection of chronic alcoholic liver damage
ActiveCN104922168ANo side effectsMultiple EffectsDigestive systemAntinoxious agentsPositive controlHigh doses
The invention discloses application of matteuccia struthiopteris total triterpenes to protection of chronic alcoholic liver damage and belongs to the technical field of biomedicine. Modeling is performed by adopting a dose incremental drinking method, and a chronic liver damage process induced by alcohol of human is simulated. Matteuccia struthiopteris total triterpenes can inhibit GOT and GPT to a certain extent, and an inhibition action is in direct proportion to dosage of administration. Purified matteuccia struthiopteris total triterpenes has higher in-vivo anti-oxidation capability, and a live protection mechanism is that the damage of alcohol to the liver is effectively relieved by enhancing the anti-oxidation capability of the body and effectively removing harmful free radicals. In the purified matteuccia struthiopteris total triterpenes, high dose can effectively relieve oxidated damage caused by factors such as lipid peroxidation in the liver and attack of the free radicals, degree of liver cell enlargement, necrosis and fatty degeneration is reduced, normal metabolism and physiological functions of the cells are regulated, and the effect thereof is superior to that of positive control medicine bifendate in a certain range, which shows that matteuccia struthiopteris total triterpenes has a certain protection action against chronic alcoholic liver damage.
Owner:SHAANXI NORMAL UNIV
Application of a traditional Chinese medicine composition in preparation of medicine for treating chronic alcoholic steatohepatitis
ActiveCN110742935BSignificant effectAnthropod material medical ingredientsDigestive systemCurative effectPharmaceutical Substances
Owner:SHANGHAI PUTUO DISTRICT CENT HOSPITAL
Traditional Chinese medicine extract mixed preparation and application thereof
InactiveCN102114102BDegree of reductionDigestive systemPlant ingredientsBaical Skullcap RootWolfiporia extensa
The invention discloses a traditional Chinese medicine extract mixed preparation which comprises a baical skullcap root extract, a cape jasmine fruit extract and an Indian buead extract, wherein the mixture ratio of the three is (80-100): (80-100): (100-150); and the content of scutelloside in the baical skullcap root extract is above 90%, the content of geniposide in the cape jasmine fruit extract is above 90%, and the content of polysaccharides in the Indian buead extract is above 50%. The traditional Chinese medicine extract mixed preparation has the effects of protecting liver and benefiting gallbladder, and can be used for preparing medicaments or health care products for protecting the liver and benefiting the gallbladder, or the medicaments for treating obstructive jaundice, or themedicament for treating cholestasis, or the medicaments for treating chronic alcoholic liver injury. The effects of the traditional Chinese medicine extract mixed preparation for and benefiting the gallbladder and protecting the cholestasis of rats caused by bile duct ligation and ANIT (alpha-naphthylisothiocyanate) and the alcoholic liver injury of the rats are obviously better than conventionalcontrol medicaments, and the liver injury degree and the icterus index can be significantly reduced.
Owner:SHANDONG ACAD OF CHINESE MEDICINE
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