40 results about "Chronic alcoholic" patented technology

An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.

The invention belongs to the technical field of medicine, and relates to a Chinese medicinal composition, in particular to a Chinese medicinal composition for treating chronic alcoholic toxic liver disease and a preparation method thereof. Aiming at the current technological defects that the chronic alcoholic toxic liver disease cannot be treated comprehensively and effectively and chemical treatment has the defects of high relapse rate and discontinuous curative effect, the Chinese medicinal composition for treating or preventing the chronic alcoholic liver toxic disease comprises the following components in parts by weight: 10 parts of corydalis tuber, 15 parts of fourstamen stephania root, 6 parts of virgate wormwood herb, 10 parts of glossy privet fruit, 10 parts of Szechuan lovage rhizome, 6 parts of Chinese angelica, 20 parts of sophora flower, 20 parts of tribulus terrestris, 10 parts of Chinese thorowax root, 12 parts of baikal skullcap root, 15 parts of baikal skullcap root, 30 parts of cassia twig, 6 parts of Indian buead and 10 parts of liquoric root. The Chinese medicinal composition has a very good treatment effect on the chronic alcoholic toxic liver disease, and has a remarkable clinical popularization value.

The invention relates to a natural medicine composition for relieving alcohol and protecting the liver. The composition is composed of total triterpene acids of loquat leaves, total flavonoids of loquat leaves, total flavonoids of japonica grape and corn silk extract. The invention also relates to the application of the composition in preparing health food for preventing and treating acute and chronic alcoholic liver injury and in preparing health food or beverage for treating non-alcoholic fatty liver. The various components of the composition of the invention produce good synergistic effects, have remarkable curative effect, and the raw materials are easy to obtain, the cost is relatively low, and the composition has strong practicability.

The invention discloses the application of total triterpenoids of Pteridocarpus to protect chronic alcoholic liver injury, and belongs to the technical field of biomedicine. A dose-escalating drinking method was used to simulate the process of chronic alcohol-induced liver injury in humans. The total triterpenoids of Pteridocarpus can inhibit GOT and GPT to a certain extent, and the inhibitory effect is positively correlated with the dose. The purified total triterpenoids of Viburnum fern have strong antioxidant capacity in vivo, and its hepatoprotective mechanism may be to effectively alleviate the damage caused by alcohol to the liver by enhancing the body's antioxidant capacity and effectively removing unfavorable free radicals. Medium and high doses of purified total triterpenoids of Viburnum fern can effectively alleviate the oxidative damage caused by lipid peroxidation and free radical attack in the liver, reduce the degree of hepatocyte enlargement, necrosis and fatty degeneration, and regulate cells to restore normal metabolism and Physiological function, its effect is better than that of the positive control drug bifendate within a certain concentration range, indicating that the total triterpenoids of Pteridocarpus have a certain protective effect on chronic alcoholic liver injury.

The invention relates to an application of a traditional Chinese medicine composition in the preparation of a medicine for treating chronic alcoholic steatohepatitis. The ratio is: 5-15 parts of rhubarb, 5-15 parts of peach kernel, and 3-9 parts of ground beetle. Extract with 30% ethanol for 1-3 times, collect and combine the extracts, recover the ethanol, and obtain the product. The present invention uses Xiayuxue Decoction to treat chronic alcoholic steatohepatitis, and obtains good curative effect, not only expands the application range of Xiayuxue Decoction, but also provides new ideas and ideas for clinical treatment of chronic alcoholic steatohepatitis method.

The invention discloses a traditional Chinese medicine extract mixed preparation which comprises a baical skullcap root extract, a cape jasmine fruit extract and an Indian buead extract, wherein the mixture ratio of the three is (80-100): (80-100): (100-150); and the content of scutelloside in the baical skullcap root extract is above 90%, the content of geniposide in the cape jasmine fruit extract is above 90%, and the content of polysaccharides in the Indian buead extract is above 50%. The traditional Chinese medicine extract mixed preparation has the effects of protecting liver and benefiting gallbladder, and can be used for preparing medicaments or health care products for protecting the liver and benefiting the gallbladder, or the medicaments for treating obstructive jaundice, or themedicament for treating cholestasis, or the medicaments for treating chronic alcoholic liver injury. The effects of the traditional Chinese medicine extract mixed preparation for and benefiting the gallbladder and protecting the cholestasis of rats caused by bile duct ligation and ANIT (alpha-naphthylisothiocyanate) and the alcoholic liver injury of the rats are obviously better than conventionalcontrol medicaments, and the liver injury degree and the icterus index can be significantly reduced.