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432 results about "Inulin" patented technology

Inulins are a group of naturally occurring polysaccharides produced by many types of plants, industrially most often extracted from chicory. The inulins belong to a class of dietary fibers known as fructans. Inulin is used by some plants as a means of storing energy and is typically found in roots or rhizomes. Most plants that synthesize and store inulin do not store other forms of carbohydrate such as starch. In the United States in 2018, the Food and Drug Administration approved inulin as a dietary fiber ingredient used to improve the nutritional value of manufactured food products. Using inulin to measure kidney function is the "gold standard" for comparison with other means of estimating glomerular filtration rate..

Fermentation composition helpful for enhancing immunity and preparation method thereof

The invention belongs to the technical field of health-care products, and particularly relates to a fermented composition beneficial to enhancing immunity and a preparation method thereof. The fermentation composition for improving immunity is prepared by taking yeast beta-glucan, an elderberry extract, glucoraphanin, sea cucumber peptide, inulin and a traditional Chinese medicine zymolyte as fermentation raw materials, firstly inoculating bacillus coagulans and staphylococcus xylosus for aerobic fermentation, and then inoculating bifidobacterium longum for anaerobic fermentation, the aerobic fermentation stage and the anaerobic fermentation stage have a synergistic effect, so that the fermentation speed can be increased, the fermentation time can be shortened, and richer nutrient substances can be provided, and therefore, the composition has an excellent effect of enhancing the immunity; the fermentation composition is applied to preparation of capsules helpful for enhancing immunity, is helpful for enhancing human immunity, and can solve the problem that active substances in existing health-care products are difficult to effectively absorb by human bodies, so that the effect of enhancing immunity is influenced.
Owner:DING MA GELI (BEIJING) BIOTECHNOLOGY CO LTD

Composition for regulating sleep rhythm homeostasis, preparation method and application thereof

The invention discloses a composition for regulating sleep rhythm homeostasis as well as a preparation method and application thereof. The composition for regulating the sleep rhythm homeostasis is prepared from the following components in percentage by weight: 5 to 18 percent of polydextrose, 9 to 15 percent of galactooligosaccharide, 1 to 10 percent of inulin, 0.4 to 2 percent of gamma-aminobutyric acid, 0.8 to 2.2 percent of L-theanine, 0.1 to 3.5 percent of magnesium citrate, 2 to 21 percent of semen ziziphi spinosae extract, 1 to 10 percent of poria cocos extract, 0.5 to 2 percent of pericarpium citri reticulatae extract, 0.3 to 1 percent of liquorice root extract and 15 to 40 percent of maltodextrin. 5-18% of coconut oil powder MCTs, and 0.5-2% of a lily extract. According to the application, a magnesium MCTs shell-core structure is delivered by maltodextrin to form a mitochondrial piezoelectric engine so as to improve prebiotics, promote flora metabolism efficiency and energy supply feedback, activate intestinal pheochromophilic cells and improve SLC6A4 gene expression so as to improve synthesis of 5-hydroxytryptamine in the brain and activate GABA energy neurons; meanwhile, through the spina date seed and poria cocos quantum dots and a pericarpium citri reticulatae and liquorice pi-pi stacking network, the blood-brain barrier penetration rate is greatly increased, and hypothalamic CRH release is adjusted.
Owner:XISHUANGBANNA SHENGZEYAO BIOENGINEERING CO LTD

Galactomannan synergistic immune regulation type prebiotic syrup

The invention relates to the technical field of functional food, in particular to immune regulation type prebiotic syrup with synergy of galactomannan. The active components of the composite solid beverage are prepared from the following raw materials in percentage by weight: 20%-35% of fructo-oligosaccharide, 10%-18% of galactooligosaccharide, 8%-15% of stachyose, 3%-7% of xylooligosaccharide, 5%-12% of lactitol, 5%-10% of galactomannan, 2%-5% of yeast beta-glucan and 1%-3% of N-acetylglucosamine. The composition further comprises 4-8% of inulin and 3-6% of resistant dextrin as a matrix filling and slow-release carrier, and the sum of the weight percentages of all the active ingredients and the carrier is 100%. By remodeling intestinal microecology and inhibiting inflammation pathways, the intestinal inflammation state can be remarkably improved, expression of intestinal mucosa tight junction protein is promoted, and an innovative solution is provided for people suffering from chronic bowel diseases and immune imbalance.
Owner:SHANDONG MINGZE BIOTECHNOLOGY CO LTD

Medicinal and edible composition compounded with gradient fermentation type prebiotics and capable of reducing blood sugar and application thereof

The invention provides a healthy food, in particular to a hypoglycemic composition based on homology of medicine and food and gradient fermentation type prebiotics, which is a dry powder preparation and comprises a component A and a component B, the component A is a medicinal and edible component, and the component B is a prebiotic component; the component A is prepared from the following components in parts by mass: 2 to 15 parts of folium mori extract, 2 to 10 parts of bitter gourd extract, 2 to 20 parts of rhizoma dioscoreae extract, 1 to 10 parts of radix puerariae extract, 2 to 10 parts of fructus lycii extract, 0.5 to 5 parts of radix polygonati officinalis extract and 0.5 to 5 parts of rhizoma polygonati extract; the component B is prepared from 20 to 50 parts of resistant dextrin, 5 to 15 parts of xylooligosaccharide, 3 to 10 parts of inulin and 35 to 50 parts of D-psicose. The hypoglycemic activity of the traditional medicinal and edible materials is organically combined with the gradient fermentation type prebiotics, so that the hypoglycemic effect is realized by synergism of multiple action mechanisms, and the problems of single hypoglycemic mechanism and non-ideal blood sugar regulation effect of the existing product are solved.
Owner:HEBEI RUNMEICHANG TECHNOLOGY DEVELOPMENT CO LTD

Multi-component inulin hydrogel as well as preparation method and application thereof

The invention discloses multi-component inulin hydrogel as well as a preparation method and application thereof, and belongs to the technical field of nano materials and medicines.The multi-component inulin hydrogel is characterized in that a medicine L-alanyl-L-glutamine contributing to intestinal mucosa repair is entrapped in the inulin hydrogel; the multi-component inulin hydrogel has the advantages that the multi-component inulin hydrogel is prepared from the inulin and composite nanoparticles (namely mesoporous polydopamine-gallium composite nanoparticles) composed of an active oxygen scavenger polydopamine and an antibacterial agent gallium ions, the repairing capacity on intestinal barriers is further enhanced, and the prepared multi-component inulin hydrogel can be used for effectively treating inflammatory bowel diseases and non-alcoholic steatohepatitis.
Owner:INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI

Plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promotion, stasis removal, thrombolysis, collateral dredging and microcirculation improvement

The invention discloses a plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promoting, blood stasis removing, thrombolysis, collateral dredging and microcirculation improving, and relates to the technical field of medicine and food homology dietary therapy. Soybean protein isolate and earthworm protein are used as core thrombolytic active raw materials, isomaltooligosacharide, xylitol, German Jilida collagen peptide, soybean peptide powder, Belgian imported inulin, red yeast rice and natto powder are compounded, microcrystalline cellulose and magnesium stearate are used as auxiliary materials, and probiotics / metabiotics strains such as rhamnolactobacilli JYLR-005 and the like can be selectively added. The raw materials have a synergistic effect through precise matching, plasmin and lumbrukinase peptide in earthworm protein can directly dissolve thrombus fibrin, natto powder and red yeast rice assist in lowering lipid and dissolving thrombus, multiple active peptides and prebiotics regulate intestinal microecology to improve microcirculation of the whole body, probiotics / metabiotics further strengthen the metabolic capacity of the body, no chemical medicine is added in the whole process, and the traditional Chinese medicine composition is free of toxic and side effects and free of toxic and side effects. The safety is high; the dietary therapy composition can achieve postoperative rehabilitation conditioning of cardiovascular and cerebrovascular diseases through daily consumption, effectively promote blood circulation to remove blood stasis, dissolve thrombus and dredge collaterals, improve microcirculation and relieve various discomfort caused by blood vessel clogging, raw materials are easy to obtain, compatibility is scientific, and the dietary therapy composition is suitable for large-scale production and popularization.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

Polygonatum cyrtonema polysaccharide and application thereof

The invention relates to polygonatum cyrtonema polysaccharide and application thereof. The novel polysaccharide PRP is extracted and purified from polygonatum cyrtonema and is neutral inulin type polysaccharide. The PRP takes a node alpha-D-glucose-(22)-beta-D-fructose similar to cane sugar as a center. The C6 site of glucose has an additional beta-fructose (2-> 6) substituent, and two chains extend out of the core through a (2-> 1)-beta-fructose bond to form a Y-type moderate branch structure. Compared with other selenium nanoparticles with stable polysaccharides, the selenium nanoparticles coated with polygonatum polysaccharide provided by the invention have smaller initial particle size, more negative zeta potential, stable batch repeatability and excellent long-term stability.
Owner:WENZHOU MEDICAL UNIV

Amino acid cleansing product and preparation method thereof

ActiveCN121337646ACosmetic preparationsToilet preparationsCarbamateIsostearyl alcohol
The invention discloses an amino acid cleansing product and a preparation method thereof. The amino acid face cleaning product is prepared from the following raw material components in percentage by mass: 10 to 30 percent of surfactant composition, 1 to 10 percent of amphoteric or nonionic surfactant, 0.05 to 0.5 percent of citric acid, 1 to 5 percent of humectant, 0.5 to 2 percent of isostearyl alcohol, 0.1 to 0.5 percent of phytosterol dimer linoleate, 0.5 to 5 percent of sodium chloride, 0.3 to 1 percent of inulin lauryl carbamate and the balance of water, the surfactant composition comprises a long-chain fatty acyl glycol acid salt. The amino acid face cleansing product keeps uniform appearance under the conditions of high temperature, low temperature and repeated freezing and thawing, has good physical and chemical stability and compatibility, has small damage to a cuticle structure under the condition of realizing sufficient cleaning, and shows good cleaning and mild effects.
Owner:GUANGZHOU BAFEORII CHEM +1

Probiotic composition for inhibiting helicobacter pylori and probiotic agent and application thereof

The invention provides a probiotic composition for inhibiting helicobacter pylori as well as a probiotic agent and application thereof, and belongs to the technical field of probiotic functional products. The probiotic composition is prepared from the following components in parts by weight: 0.05 to 2 parts of a pediococcus pentosaceus strain A21358, 0.01 to 1.5 parts of a plant lactobacillus strain A21136, 0.05 to 1.5 parts of a lactobacillus rhamnosus strain A21149 and 0.03 to 1.2 parts of a lactobacillus reuteri strain A21325. The probiotic agent comprises the probiotic composition, resistant dextrin, xylooligosaccharide, erythritol, inulin, fructo-oligosaccharide, hericium erinaceus powder, fucoidin and at least one fruit powder selected from grape powder, passion fruit powder and kiwi fruit powder, wherein the specific weight parts of the resistant dextrin, the xylooligosaccharide, the erythritol, the inulin, the fructo-oligosaccharide, the hericium erinaceus powder, the fucoidin and the at least one fruit powder are selected from grape powder, passion fruit powder and kiwi fruit powder. The probiotic agent has the effect of inhibiting helicobacter pylori, and a new thought is provided for clinical related auxiliary treatment of helicobacter pylori infection.
Owner:SICHUAN AISHENG LIFE TECHNOLOGY CO LTD +2

An amino acid cleansing product and a method for preparing the same

ActiveCN121337646BCosmetic preparationsToilet preparationsCarbamateIsostearyl alcohol
The application discloses an amino acid cleansing product and a preparation method thereof. The amino acid cleansing product comprises the following raw material components in percentage by mass: a surfactant composition 10-30%, an amphoteric or non-ionic surfactant 1-10%, citric acid 0.05-0.5%, a humectant 1-5%, 0.5-2% isostearyl alcohol, 0.1-0.5% phytosteryl dimer dilinoleate, 0.5-5% sodium chloride, 0.3-1% inulin lauryl carbamate, and the balance is water; the surfactant composition comprises long-chain fatty acyl glycolate. The amino acid cleansing product of the application maintains uniform appearance under high temperature, low temperature and repeated freezing and thawing conditions, has good physical and chemical stability and compatibility, and at the same time, realizes sufficient cleaning and has less damage to the stratum corneum structure, thereby showing good cleaning and mildness.
Owner:GUANGZHOU BAFEORII CHEM +1

Dietary fiber particles of isomaltitol and preparation method of dietary fiber particles

The invention relates to the technical field of solid beverages, in particular to isomaltitol dietary fiber particles and a preparation method thereof, and the isomaltitol dietary fiber particles comprise the following components: isomaltitol, Chinese date mulberry extract, golden flower Tibetan tea powder, fructo-oligosaccharide, polydextrose, xylooligosaccharide, stachyose, insoluble dietary fiber, inulin, konjac glucomannan and lycium barbarum polysaccharide. By processing the raw materials and optimizing the process, the problems of poor taste, low stability, single function and the like of the existing dietary fiber product are solved. The application of the microencapsulated isomaltitol and the ultrahigh pressure treated inulin respectively realizes the slow-release control of a sweetening agent and the improvement of the solubility of polysaccharide fibers, and the flavor adjustment of the Chinese date mulberry extract and the decaffeinated golden flower Tibetan tea powder, so that the product has high dietary fiber content and also has fresh and sweet fruit fragrance and elegant tea fragrance; and the taste is fine and caking-free.
Owner:贵州四季常青药业有限公司

A fresh dog food for improving coat health and its preparation method

This invention relates to the field of pet nutrition technology, and more particularly to a fresh dog food for improving coat health and its preparation method. The fresh dog food of this invention comprises component A and component B. Component A includes the following components in parts by weight: 40-45 parts venison, 10-12 parts mussels, 8-10 parts chicken liver, 8-10 parts duck egg, 3-5 parts carrot, 3-5 parts broccoli, 3-5 parts pumpkin, 3-5 parts taro, 3-5 parts avocado, 0.8-1 part dried red dates, 0.8-1 part dried rose petals, 0.5 parts whey calcium, 1.3 parts malt powder, 0.5 parts inulin, 0.5 parts brewer's yeast, and 0.2 parts fish oil. Component B is Bacillus subtilis; the viable count of Bacillus subtilis is 1×10⁻⁶. 9 CFU / g. This invention utilizes the synergistic effect of deep-sea shellfish and venison to improve the coat quality of puppies, increasing the coat diameter by ≥23.1% and the scale thickness by ≥32.4%.
Owner:CHONGZHI TECHNOLOGY (SHENZHEN) CO LTD +1

Lithium cross-linked synanthrin, preparation method thereof and application of lithiated cross-linked synanthrin in organic / inorganic composite solid electrolyte

The invention discloses lithiated cross-linked synanthrin, a preparation method thereof and application of the lithiated cross-linked synanthrin in an organic / inorganic composite solid electrolyte, and relates to the technical field of polymers and solid electrolytes. The lithiated cross-linked synanthrin provided by the invention is prepared by taking sodium hexametaphosphate and the like as a cross-linking agent to cross-link synanthrin and then adding lithium salt to lithiate the cross-linked synanthrin in an ion exchange manner, so that the stability of an organic / inorganic interface in an organic / inorganic composite solid electrolyte can be improved; the composite strength of the organic electrolyte and the inorganic electrolyte is improved, and meanwhile, the three-dimensional cross-linked structure can introduce an additional lithium ion transmission channel into an electrolyte matrix. Based on this, the composite electrolyte prepared by the invention can have significantly improved ionic conductivity and a wider electrochemical window.
Owner:GANJIANG INNOVATION ACAD CHINESE ACAD OF SCI

Low-GI blackcurrant jam and preparation method thereof

The present invention discloses a low GI blackcurrant jam and a preparation method thereof, and relates to the technical field of food processing, the low GI blackcurrant jam comprises the following components by mass: 50-70 parts of blackcurrant pulp, 15-35 parts of a composite sugar source, 0.3-1.5 parts of a compound thickener, 0.1-0.7 part of an acidity regulator, and 5-15 parts of water; the composite sugar source consists of psicose, inulin and resistant dextrin; the compound thickening agent is prepared from apple gum, konjac gum and xanthan gum; the preparation process comprises the following steps: step-by-step sugar melting under a mild condition, colloid pre-dispersing gel melting, fruit pulp mixing, pasteurization, acid regulation and homogenization, sterilization after filling and the like. Through the cooperation of a formula system and a whole-process mild temperature control process, a stable three-dimensional gel network is constructed while the low GI value and the high vitamin C retention rate of the product are achieved, water bleeding and layering are effectively prevented, and therefore the jam product with the healthy property and the excellent texture is obtained.
Owner:JIANGSU HOWBETTER FOOD CO LTD

Lactobacillus helveticus postbiotic complex and application thereof in treatment of constipation

The invention discloses a lactobacillus helveticus metaplasm complex and application thereof in constipation treatment, and relates to the technical field of constipation treatment, a specific lactobacillus helveticus KLDS 1.1 1105 strain is adopted, and metaplasm is prepared through fermentation and spray drying. The invention further provides a three-layer embedded compound structure. The outer layer is composed of pitaya powder and prune powder and is used for rapidly relaxing the bowels; the middle layer contains a pomegranate peel extract and is used for regulating flora; the core is colon-targeted lactobacillus helveticus metagen and inulin and is used for long-acting regulation. According to the compound, through the multi-target synergistic effect, gastrointestinal hormone is regulated, related signal channels are activated, the function of intestinal pace-making cells is promoted, and generation of short-chain fatty acid is increased, so that the constipation symptom is rapidly relieved, meanwhile, the intestinal function is fundamentally repaired, and the intestinal microecology is improved. The product disclosed by the invention is good in stability, high in safety and suitable for preparing medicines or functional foods for treating functional constipation.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Traditional Chinese medicine composition for improving spleen and stomach health and preparation method thereof

The invention provides a traditional Chinese medicine composition for improving spleen and stomach health and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 25 to 30 parts of rhizoma dioscoreae, 15 to 20 parts of rhizoma atractylodis macrocephalae, 8 to 15 parts of fructus aurantii, 10 to 15 parts of red dates, 8 to 12 parts of liquorice root, 10 to 15 parts of inulin, 6 to 10 parts of fructus amomi and 5 to 8 parts of cassia twig. The lauric acid modified fenugreek gum (LA-FG) is used as an emulsifier and an immobilized enzyme carrier to construct a water-oil two-phase enzymolysis system, so that the content of effective active ingredients in the traditional Chinese medicine composition, the product stability and the bioavailability are remarkably improved. In addition, the traditional Chinese medicine composition can effectively improve the gastric emptying rate and the small intestine propulsion rate, the level of motilin and anti-inflammatory factors IL-10 is improved, and the effect of improving spleen and stomach health is achieved through multi-target-point synergism. The method successfully breaks through double limitations of a traditional process and an existing scheme, effectively considers volatile oil protection, efficient enzymatic conversion and system stability, and provides a new path for promoting technical upgrading of the traditional Chinese medicine industry.
Owner:FIRST AFFILIATED HOSPITAL OF ANHUI UNIV OF CHINESE MEDICINE +1

Method for storing inulin juice

PendingCN121039168ABiotechnologyInulin
The present invention relates to a method for storing an inulin juice, the method comprising the steps of: (a) providing an inulin juice at a temperature of from about 80 DEG C to about 100 DEG C wherein the inulin juice has a solids content of from 20 wt% to 60 wt%; (b) cooling the inulin juice in the crystallization tank to a temperature of up to about 40 DEG C at an average cooling rate of 0.4 DEG C to 20 DEG C per hour, wherein the inulin juice is stirred during the cooling step; (c) conveying the inulin juice from the crystallizing tank to a storage tank; and (d) maintaining the inulin juice at a temperature of up to about 40 DEG C in the storage tank. After storage, the inulin juice can be advantageously used to prepare one or more natural inulin products, long-chain inulin products, or short-chain inulin products.
Owner:COSUCRA GRP WARCOING

A highland barley sourdough, a low-gi highland barley sourdough bread and a preparation method thereof

The application belongs to the technical field of food processing, and specifically discloses a highland barley sourdough, low-GI highland barley sourdough bread and a preparation method thereof. The highland barley sourdough is prepared by fermentation of Lactobacillus plantarum JYLP-326, highland barley flour and water. The low-GI highland barley sourdough bread prepared from the highland barley sourdough comprises the following components in parts by mass: 20-22 parts of highland barley flour, 22-28 parts of wheat flour, 36-40 parts of highland barley sourdough, 48-50 parts of water, 4-6 parts of bran, 4-6 parts of oat beta-glucan, 4-6 parts of inulin, 4-8 parts of gluten, 1-2 parts of yeast, 1-2 parts of salt and 4-6 parts of butter. The GI highland barley sourdough bread prepared by using the highland barley sourdough provided by the application has the advantages of low in-vitro glycemic index, low starch hydrolysis rate, high loft and softness, good taste and high appearance quality.
Owner:HEBEI AGRICULTURAL UNIV.

A composition containing potato extract and having a prolonged satiety effect, and a method of preparing and using the same

The present application relates to a kind of compositions containing potato extract and with extended satiety and its preparation method and application, and the composition includes the following weight parts of raw materials: plant extract 30-40 parts, protein component 10-20 parts, dietary fiber component 30-40 parts and auxiliary materials 5-10 parts;Wherein, the plant extract includes potato extract, white kidney bean extract, tea flower extract and lotus leaf extract, the protein component is at least one in pea protein, soybean protein and oat protein, the dietary fiber component is the combination of inulin, resistant dextrin, psyllium husk powder, apple fiber powder and citrus fiber powder.The composition of the present application has significant advantages in controlling body weight and managing satiety, and realizes the weight loss effect of "reducing heat absorption, extending satiety and promoting metabolism" in multiple dimensions, forms sustainable metabolic health support long-term value, and can be used for preparing weight loss body shaping functional food.
Owner:GUANGDONG OCEAN UNIVERSITY +1

Freeze-drying protectant for vibrio harveyi phage v-ydf132 and preservation method thereof

The application discloses a freeze-drying protective agent of Vibrio harveyi phage V-YDF132 and a preservation method thereof. The freeze-drying protective agent contains inulin, skimmed milk powder, gelatin, L-glutamic acid sodium and water. The freeze-drying protective agent is mixed with a phage V-YDF132 solution, and then the mixture is frozen to a solid state, and after being subjected to freeze-drying, a phage V-YDF132 freeze-drying powder preparation is obtained. There are various preservation methods for phages, and the best preservation method is different for different phages. The application screens and prepares different phage freeze-drying protective agents and explores the protection effect of the freeze-drying protective agents on phages after freeze-drying, so as to lay a foundation for phage preservation. The phage powder preparation prepared from the freeze-drying protective agent formula P9 and the phage V-YDF132 has low requirements on the preservation conditions and can be long-term preserved without losing biological activity.
Owner:SOUTH CHINA AGRICULTURAL UNIVERSITY

Pet food with hair beautifying, hair brightening and hair protecting effects and preparation method thereof

PendingCN122350230ABiotechnologyYolk
This invention discloses a pet food with coat-enhancing, shine-promoting, and coat-protecting effects, its preparation method, and applications. The food comprises the following components: chicken meal, fresh chicken meat, duck meal, sardine meal, chicken liver, sweet potato meal, corn meal, chicken heart, beef bone meal, duck meat pear, chicken oil, and egg yolk granules; coriander root powder, inulin, seaweed powder, beet pulp, flaxseed, fish oil, cranberry powder, carrot, krill, honeysuckle, turmeric, chrysanthemum, mannan oligosaccharide, lactulose, etc. The raw materials and auxiliary ingredients of this pet food are widely available, palatable, inexpensive, and readily available. The coriander root powder, other auxiliary ingredients, and nutritional supplements / additives work synergistically to improve the shine of the pet's coat, promote growth, and maintain coat health, while also improving the microstructure of the hair cuticle, fundamentally preventing pet coat health problems. The pet food preparation method disclosed in this invention is simple to operate, safe, and environmentally friendly, and is particularly suitable for feed products with high humidity and high heat sensitivity.
Owner:YANGZHOU UNIV

Preparation method of targetable temperature-sensitive drug-loaded composite microspheres based on attapulgite

The embodiment of the application discloses a preparation method of a target temperature-sensitive drug-loaded composite microsphere based on attapulgite, which comprises the following steps: carrying out purification treatment on original attapulgite based on an aqueous solution of inorganic strong acid to obtain purified attapulgite; mixing the purified attapulgite, gypenoside, inulin and folic acid to obtain a mixture, and carrying out mixing treatment on the mixture based on deionized water to obtain a composite microsphere suspension; conveying the composite microsphere suspension into a spray dryer to carry out granulation to obtain primary drug-loaded composite microspheres; adopting a melt impregnation method to coat lauric acid on the surface and pores of the primary drug-loaded composite microspheres, and cooling the primary drug-loaded composite microspheres coated with lauric acid to room temperature to obtain the target temperature-sensitive drug-loaded composite microspheres. The application can not only realize temperature change-based on-off type control release of drugs, significantly improve the targeting and treatment accuracy of drugs, but also reduce the systemic toxic side effects of chemotherapy from the source, and realize efficient and low-toxicity synergistic treatment.
Owner:CHONGQING UNIV

Composite condensing gel based on photodynamic therapy and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, in particular to composite condensing gel based on photodynamic therapy and a preparation method of the composite condensing gel. The preparation method of the composite condensate gel based on photodynamic therapy comprises the following steps: preparing a BSA (Bovine Serum Albumin) solution, uniformly mixing an inulin mother solution with the BSA solution, adjusting the pH value, heating in a water bath, cooling to room temperature, adding 5-aminolevulinic acid methyl ester hydrochloride into the condensate gel, adding an acid coagulant, diluting, and filling CO2 gas. According to the invention, CO2 is added into the composite condensation gel, so that the binding force of hemoglobin and O2 in tissues absorbing the composite condensation gel is reduced, and the concentration of free oxygen is improved, so that the composite condensation gel can transfer energy to surrounding oxygen and generate singlet oxygen with strong activity, thereby killing cancer cells and achieving the effect of improving the curative effect of photodynamic therapy.
Owner:HANGZHOU WELLCOME MEDICAL DEVICES CO LTD

Mulberry leaf peptide dietary fiber composite meal replacement powder and preparation method thereof

The invention provides mulberry leaf peptide dietary fiber composite meal replacement powder and a preparation method thereof. The mulberry leaf peptide dietary fiber composite meal replacement powder comprises the following components in parts by weight: 15-35 parts of mulberry leaf peptide powder; 45 to 65 parts of soluble dietary fiber; 10 to 25 parts of a low GI carbohydrate; 1-3 parts of a compound stabilizer; wherein the mulberry leaf peptide powder is high-purity oligopeptide obtained after low-temperature continuous enzymolysis and activated carbon-beta-cyclodextrin composite debitterizing, the molecular weight distribution is 300-800 Da, and the peptide content is not lower than 80%; the soluble dietary fiber comprises inulin and resistant dextrin which are compounded according to the mass ratio of 1: (1-1.5). The mulberry leaf peptide powder is prepared by combining low-temperature continuous enzymolysis with an activated carbon-beta-cyclodextrin composite debitterizing system, high-temperature inactivation and bitter taste residues are avoided, the molecular weight of the obtained peptide is concentrated at 300-800 Da, the peptide content is not lower than 80%, the peptide can be rapidly dissolved in water, and the problems that traditional vegetable protein meal replacement powder is poor in solubility and rough in taste are solved.
Owner:江西省经济作物研究所

Protein soft sweets based on olive pomace extract as well as preparation method and application of protein soft sweets

The invention discloses protein soft sweets based on an olive pomace extract as well as a preparation method and application of the protein soft sweets. The protein soft sweets mainly consist of the following components in parts by mass: 10-50 parts of the olive pomace extract, 10-80 parts of collagen, 10-40 parts of gelatin, 1-20 parts of inulin, 1-10 parts of glucose syrup, 1-5 parts of malic acid and 1-5 parts of sodium citrate. The protein soft sweets based on the olive pomace extract have olive flavor, are amber, are crystal clear, glossy and rich in olive flavor before being sprayed with powdered sugar, and are moderate in viscosity, not sticky to teeth and good in elasticity and resilience after being sprayed with powdered sugar; the olive pomace extract prepared by the preparation method disclosed by the invention also has relatively high oxidation resistance, shows very high scavenging ability in the aspects of DPPH free radical scavenging ability and ABTS < + > free radical scavenging ability, has the free radical scavenging ability of the olive pomace extract, is beneficial to preventing oxidative damage and maintaining health, and can be used as an antioxidant functional food.
Owner:ZHONGKAI UNIV OF AGRI & ENG

Preparation method of collagen micromolecule active peptide and bioactive peptide for inhibiting cancer cell proliferation and improving intracellular environment

The invention discloses a preparation method of collagen micromolecule active peptide and bioactive peptide for inhibiting cancer cell proliferation and improving intracellular environment, and belongs to the technical field of bioactive peptide preparation and biological functional raw materials. According to the method, bone collagen peptide, cartilage peptide (hydrolyzed II-type collagen peptide), collagen peptide (German Jilida), non-denatured II-type collagen peptide and yak bone marrow peptide are taken as core raw materials, and optional ingredients such as bovine bone marrow peptide powder, shark cartilage peptide and Belgian imported inulin can be compounded as required; through a step-by-step preparation process comprising the steps of graded purification pretreatment of raw materials, precise proportioning and mixing, low-temperature activation and synergism and stable micro-capsule embedding, structure protection and efficacy synergy of each collagen small-molecule active peptide and bioactive components are realized; the prepared bioactive peptide product can significantly inhibit cancer cell proliferation, regulate intracellular oxidation-reduction balance and improve intracellular microenvironment, the preparation process is mild and free of high-temperature damage, the raw material biological activity retention rate is high, the raw material source is controllable, the large-scale production feasibility is high, and the bioactive peptide product can be widely applied to preparation in the fields of functional food, bioactive raw materials and the like.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

Soluble fiber solid beverage and preparation method thereof

The invention belongs to the technical field of nutritious food, discloses a soluble fiber solid beverage and a preparation method thereof, and solves the problems of single component, lack of functional synergy and insufficient universality of the existing soluble fiber solid beverage. The soluble fiber solid beverage is prepared from the following components in parts by weight: 1 to 2 parts of alginate oligosaccharide, 25 to 40 parts of resistant dextrin, 20 to 30 parts of inulin, 15 to 25 parts of polydextrose, 10 to 20 parts of fructo-oligosaccharide, 3 to 5 parts of stachyose and 0.1 to 0.3 part of stevioside. The total soluble fiber content can reach 88.5%, the dissolution time is only 2.3 s, the particle size of undissolved particles is smaller than or equal to 5 microns, the abdominal distension occurrence rate is 6.0%, the gas production rate is 10.0%, and the low-sugar-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low
Owner:QINGDAOJUDAYANGHAIZAO CO LTD

Wheat bran araboxylan and application thereof

The invention belongs to the technical field of biological medicine, and particularly relates to wheat bran araboxylan and application thereof. The invention provides wheat bran AX with specific molecular weight and monosaccharide composition. The wheat bran AX comprises the following monosaccharides: 0.20%-0.22% of glucuronic acid, 0.58%-0.62% of galacturonic acid, 0.21%-0.23% of rhamnose, 0.6%-0.7% of glucose, 1.4%-1.5% of galactose, 18%-19.2% of xylose and 21%-23% of arabinose. Compared with commercially available wheat bran AX, inulin, fructo-oligosaccharide and other common dietary fibers, the self-made wheat bran AX has higher diversity of microbial communities in the fermentation process, has a better intestinal flora regulating effect, further has a good relieving effect on the abnormal glucose and lipid metabolism of the body, and can be used for preventing and treating the abnormal glucose and lipid metabolism of the body. Therefore, the traditional Chinese medicine composition has a good regulation effect on various diseases such as non-alcoholic fatty liver and the like caused by abnormal glucose and lipid metabolism of the organism.
Owner:SHANDONG ACADEMY OF AGRICULTURAL SCIENCES +1