44 results about "Galactitol" patented technology

A composition containing at least one polyol and certain amounts of inulin relative to the at least one polyol, characterized by a reduced tendency of the at least one polyol to induce acute diarrhea. The at least one polyol may be, for example: xylitol, sorbitol, maltitol, mannitol, isomalt, isomaltitol, lactitol, hydrogenated starch hydrolysates (HSH), glycerol, propylene glycol, erythritol, galactitol and combinations thereof. The composition also contains inulin in amounts sufficient to at least partially reduce, or eliminate, the tendency of the polyol to induce acute diarrhea. Foodstuffs, including drinks and beverages, contain said compositions.

The present invention relates to a natural deodorant system and a natural system for topical and systemic delivery of active ingredients, both systems being primarily free of, preferably substantially free of, more preferably essentially free of, and most preferably completely free of ethoxylates or other petrochemical derivatives, and comprising: (a) at least one of (1) glycerine (preferably of plant origin), (2) a polyol selected from the group consisting of galactitol, erythritol, inositol, ribitol, dithioerythritol, dithiothreitol, (3) a sugar alcohol, selected from the group consisting of mannitol, sorbitol, xylitol and maltitol, (4) a hydrogenated starch hydrosylates of at least one of berries, apples or plums, and (5) mixtures thereof; (b) water or a lower monohydric alcohol, selected from the group of methanol, ethanol, propanol and isoproponal, or mixtures thereof, present at a combined concentration of at least 20%; (c) one or more carrageenans (preferably of plant origin) or alginates, or mixtures thereof, present in combined concentrations of less than about 2%; and (d) optionally, one or more thickeners or gums selected from the group consisting of tara, guar, xanthan, Arabic, tragacanth, agar, locust bean gum, ghatti and microcrystalline celluloses.

The invention discloses sugar-free starch gel candy and a preparation method thereof, and belongs to the technical field of production of candy. A formula of the candy comprises the following components: 5 to 20 percent of starch, 50 to 90 percent of one or more of sorbitol, mannitol, xylitol, maltitol, isomaltitol, galactitol and erythritol, 0 to 0.1 percent of edible acid, 0 to 5 percent of edible lipid, 0 to 0.02 percent of edible pigment, 0 to 2.0 percent of edible essence, and 0 to 20 percent of fruit juice or vegetable juice. The preparation method comprises the following steps of: proportioning, performing acid hydrolysis, sugaring off, adding auxiliary materials for blending, pouring, forming, demoulding, finishing, packing and the like. The sugar-free starch gel candy prepared by the method does not contain sucrose, and is suitable for special patients suffering from diabetes, hypertension and the like to eat. The sugar-free starch gel candy has a good forming effect, is high in chewing strength, non-sticky for teeth and knives, easy to cut and difficult to crystallize, separate out and fade, avoids decayed teeth, and facilitates industrialized production; and the quality guarantee period of the candy can reach 24 months.

The invention discloses total oligose in cistanche deserticola and a preparation method and application thereof. In the total oligose in cistanche deserticola of the invention, the content of the contained total oligose is not less than 40 to 60 percent based on glucose (C6H12O6), and the content of galactitol (C6H1>O6) contained in the total oligose ranges from 0.0 to 25.0 percent. Used as drugs for relaxing bowel, the total oligose in cistanche deserticola of the invention eliminates the complex purification process required by purifying the galactitol from the cistanche deserticola, leads to maximum utilization of drug resources of cistanche deserticola and enhances the drug effect, thus having the advantages of definite healing efficacy, few side-effects and large group of application people. Due to moderate bowel-relaxing effect, the total oligose in cistanche deserticola is especially suitable for the old, lying-in women or valetudinarians.

A polyester including at least one furandicarboxylate unit, at least one saturated, linear or branched, diol unit including from 2 to 10 carbon atoms, and at least one bicyclic diol unit, the said bicyclic diol being chosen from: isosorbide, isoidide, isomannide, 2,3:4,5-di-O-methylene-galactitol, and 2,4:3,5-di-O-methylene-D-mannitol. The glass transition temperature of the polyester is greater than or equal to 90° C. Processes for preparing this polyester are also described.

The invention discloses a pharmaceutical composition for treating acute or chronic myeloblastic leukemia, which is characterized in that: it is made of dehydrated galactitol, kudzuvine root and pharmaceutical auxiliary materials. The composition in the invention has evident effect for treating leukemia, has an undoubted effect for treating lung cancer, multiple myeloma and nasopharyngeal carcinoma, especially has a preferable near term effect for treating chronic myeloblastic leukemia with a remission rate of 86%, has a higher effect for treating various lung cancer, and has lower poisonous and side effects.

The invention provides a method for extracting and preparing galactitol and a component containing the galactitol from a cistanche medicinal material or waste residue liquid of cistanche glycoside extraction. The galactitol is an active constituent of the cistanche for taking the effect of loosing the bowel to relieve constipation and can be used as an additive of a functional health-care food preparation. The invention solves the problem of sufficient utilization of cistanche water-soluble residue liquid, improves the utilization value of cistanche plant resources and has good market development prospect.

The invention discloses a method for extracting xylitol and D-galactitol from xylose mother solution, which adopts a homologous exchange method to construct a bacillus subtilis 168 xylose isomerase gene (xylA) deficient strain Bsxyl, utilizes the engineering strain Bsxyl to purify xylose mother solution to obtain xylose and D-galactose and further carries out catalytic hydrogenation and crystallization separation to obtain xylitol and galactitol. The Bsxyl strain is already stored in the China General Microbiological Culture Collection Center on March 25, 2010, the strain accession number of the Bsxyl strain is CGMCC No.3692, and the strain can purify xylose mother solution to obtain xylose and D-galactose. The strain can purify fermentation culture solution containing xylose mother solution, so that the total purity of xylose and galactose can reach more than 88.8 percent, and after further catalytic hydrogenation and crystallization separation, obtaining xylitol and D-galactitol the purity of which is more than 98 percent.

The present invention provides an efficient method of synthesizing and purifying dianhydrohexitols such as dianhydrogalactitol. In general, as applied to dianhydrogalactitol, the method comprises: (1) reacting dulcitol with a concentrated solution of hydrobromic acid at a temperature of about 80° C. to produce dibromogalactitol; (2) reacting the dibromogalactitol with potassium carbonate in t-butanol to produce dianhydrogalactitol; and (3) purifying the dianhydrogalactitol using a slurry of ethyl ether to produce purified dianhydrogalactitol.

The invention discloses a method for simultaneously detecting 22 sugars, sugar alcohol and alcohol in fruit juice, and belongs to the field of analytical chemistry. The method adopts an integral impulse ampere-ion chromatography to research experiment factors affecting component separation via a processing method before optimization; and the method for simultaneously detecting the 22 sugars, the sugar alcohol and the alcohol (2,3-butanediol, propylene glycol, methyl alcohol, glycerin, erythritol, xylitol, rhamnose, arabitol, sorbitol, trehalose, galactitol, mannitol, 2-deoxidized-D-glucose, arabinose, melibiose, glucose, galactose, fructose, ribose, saccharose, raffinose and maltose) at a time is built. The technical difficulty of accurately analyzing the plurality of components, sugars, sugar alcohol and alcohol, in the fruit juice is solved; the method is fast, accurate and sensitive, achieves simultaneous analysis of the plurality of categories and the plurality of components, and makes an important contribution to component detection of the fruit juice.

This invention relates to an isolated nucleic acid fragment encoding a galactinol synthase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the galactinol synthase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the galactinol synthase in a transformed host cell.

Novel compounds, called liamocins from Aureobasidium pullulans, having the general structure in Formula 1 are disclosed.where R1 is either COCH3 or H; and R2 is between two to ten O-linked 3,5-dihydroxydecanoate; and R3 can be a polyol (e.g., L- or D-glycerol, L- or D-threitol, L- or D-erythritol, L- or D-arabitol, L- or D-xylitol, L- or D-lyxitol, L- or D-ribitol, L- or D-allitol, L- or D-altritol, L- or D-mannitol, L- or D-iditol, L- or D-gulitol, L- or D-glucitol (also called sorbitol), L- or D-galactitol (also called dulcitol), and L- or D-talitol), 2-amino-D-mannitol, 2N-acetylamino-D-mannitol, L-rhamnitol, or D-fucitol; except when R3 is D-mannitol, R2 is not 2 nor 3 O-linked 3,5-dihydroxydecanoate chains. These liamocins described above in addition to D-mannitol liamocin A1, D-mannitol liamocin A2, D-mannitol liamocin B1, and D-mannitol liamocin B2, alone or in combination with each other, can be used to kill certain bacteria and to treat certain bacterial infections.

Described herein are polymorphic forms of 1,6-dibromo-1,6-dideoxy-dulcitol (dibromo dulcitol or DBD), which is a known antitumor agent. Also described are methods of making these new crystalline polymorphic forms as well as methods of using these polymorphic forms to treat cancer.

The invention discloses a herba cistanche extract and an application thereof in preparation of cosmetics. The extract is prepared from the following components: echinacoside, acteoside, polyphenol, herba cistanche extract polypeptide, galactitol, betaine and soluble polysaccharide. The preparation method comprises the following steps: S1, washing, slicing and drying herba cistanche; S2, crushing dry herba cistanche slices, dissolving the herba cistanche powder in distilled water, and uniformly mixing the mixed solution; S3, pressurizing and filtering the herba cistanche mixed solution by a filter membrane to obtain a filtrate for later use; S4, eluting and purifying the filtrate by chromatography to obtain the herba cistanche extract, and mixing the herba cistanche extract with PEG 6000, ethyl laurate, glycerol, polyethylene castor oil, polydimethysiloxane and polysorbate-80 and cetyl stearyl glucoside to prepare cosmetic composition. The extraction process of the herba cistanche extract is simple, and the extracted finished product has high purity, is extracted from pure natural plants and has the advantages of being safe and free of side effect.

The present invention provides an efficient method of synthesizing and purifying dianhydrohexitols such as dianhydrogalactitol. In general, as applied to dianhydrogalactitol, the method comprises: (1) reacting dulcitol with a concentrated solution of hydrobromic acid at a temperature of about 80° C. to produce dibromogalactitol; (2) reacting the dibromogalactitol with potassium carbonate in t-butanol to produce dianhydrogalactitol; and (3) purifying the dianhydrogalactitol using a slurry of ethyl ether to produce purified dianhydrogalactitol.

The invention discloses total oligose in cistanche deserticola and a preparation method and application thereof. In the total oligose in cistanche deserticola of the invention, the content of the contained total oligose is not less than 40 to 60 percent based on glucose (C6H12O6), and the content of galactitol (C6H1>O6) contained in the total oligose ranges from 0.0 to 25.0 percent. Used as drugsfor relaxing bowel, the total oligose in cistanche deserticola of the invention eliminates the complex purification process required by purifying the galactitol from the cistanche deserticola, leads to maximum utilization of drug resources of cistanche deserticola and enhances the drug effect, thus having the advantages of definite healing efficacy, few side-effects and large group of applicationpeople. Due to moderate bowel-relaxing effect, the total oligose in cistanche deserticola is especially suitable for the old, lying-in women or valetudinarians.

The invention relates to a preparation method for coproducing high-purity galactooligosaccharide and galactitol, which comprises the following steps: a) enabling galactosy transferase to act on a lactose solution, thus generating a galactooligosaccharide mixed saccharide solution; b) purifying galactooligosaccharide and miscellaneous saccharide components containing lactose, glucose and the like through a chromatographic separation technology, wherein the purity of the galactooligosaccharide is up to 90% or above; c) degrading the purified and separated miscellaneous saccharides by using lactase; d) by taking skeletal nickel as a catalyst, under the conditions that the temperature is 80-130 DEG C and the pressure is 8-12 Mpa, performing hydrogenation reaction on the enzyme-degraded miscellaneous saccharide components, thus preparing mixed saccharide alcohol; e) performing chromatographic separation and purification on the hydrogenated mixed saccharide alcohol solution, thus producing high-purity galactitol and miscellaneous alcohol components containing sorbitol and the like; and f) respectively performing activated carbon decoloring, ion exchange desalting and vacuum concentration on the galactooligosaccharide, galactitol and sorbitol after chromatographic separation, thus obtaining corresponding products.

The invention provides an aqueous solution preparation of citrate and sugar alcohol for aerosol inhalation for reducing phlegm. The sugar alcohol is any one selected from the group consisting of mannitol, sorbitol, inositol, galactitol, xylitol, arabitol and erythritol, and has the advantages of greatly reducing the adverse reaction of dry throat and sore throat caused by the citrate and improvingthe administration concentration of the citrate at the same time.

A polyester copolymer, having a number average molecular weight of equal to or more than 5000 grams / mole and having a glass transition temperature of less than 160° C., containing:(a) in the range from equal to or more than 25 mole % to equal to or less than 49.9 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more bicyclic diol monomer units, wherein such one or more bicyclic diol monomer units is / are derived from one or more bicyclic diols chosen from the group consisting of isosorbide, isoidide, isomannide, 2,3:4,5-di-O-methylene-galactitol and 2,4:3,5-di-O-methylene-D-mannitol;(b) in the range from equal to or more than 45 mole % to equal to or less than 50 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of an oxalate monomer unit;(c) in the range from equal to or more than 0.1 mole % to equal to or less than 25 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more linear C2-C12 diol monomer units, wherein such one or more linear C2-C12 diol monomer units is / are derived from one or more linear C2-C12 diols; and(d) optionally equal to or more than 0 mole % to equal to or less than 5 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more additional monomer units.A process for producing such a polyester copolymer, a composition containing such polyester copolymer, a method for manufacturing an article comprising the use of one or more of such polyester copolymers and an article obtained or obtainable by such a method.

The invention relates to a preparation method for coproducing high-purity galactooligosaccharide and galactitol, which comprises the following steps: a) enabling galactosy transferase to act on a lactose solution, thus generating a galactooligosaccharide mixed saccharide solution; b) purifying galactooligosaccharide and miscellaneous saccharide components containing lactose, glucose and the like through a chromatographic separation technology, wherein the purity of the galactooligosaccharide is up to 90% or above; c) degrading the purified and separated miscellaneous saccharides by using lactase; d) by taking skeletal nickel as a catalyst, under the conditions that the temperature is 80-130 DEG C and the pressure is 8-12 Mpa, performing hydrogenation reaction on the enzyme-degraded miscellaneous saccharide components, thus preparing mixed saccharide alcohol; e) performing chromatographic separation and purification on the hydrogenated mixed saccharide alcohol solution, thus producing high-purity galactitol and miscellaneous alcohol components containing sorbitol and the like; and f) respectively performing activated carbon decoloring, ion exchange desalting and vacuum concentration on the galactooligosaccharide, galactitol and sorbitol after chromatographic separation, thus obtaining corresponding products.

The invention discloses a synthesis method of L-galactose, which comprises the following steps: taking galactitol and oxidized nicotinamide adenine dinucleotide disodium salt, mixing, adding mannitol dehydrogenase and NADH oxidase, and reacting to generate L-galactose; or taking and mixing D-galactose and reduced nicotinamide adenine dinucleotide disodium salt, adding mannitol dehydrogenase and D-galactose reductase for a reaction, and generating L-galactose. According to the method, cheap and bulk D-galactose or galactitol in the market is adopted as a raw material, and expensive L-galactose is obtained through one-step or two-step direct conversion by utilizing an enzyme catalyst. The preparation scheme has multiple industrial application advantages, the used raw materials are cheap, the preparation route is short, the reaction conditions are simple, and the waste emission is low; and the characteristics well meet the basic requirements of current green industrial production.

A conductive pattern forming ink for forming a conductive pattern on a substrate by a droplet discharge method includes: metal particles; an aqueous dispersion medium in which the metal particles are dispersed; galactitol; and a polyglycerol compound having a polyglycerol skeleton. In the ink, H shown in the following formula (I) is 0.10 to 0.60;H=OH(A)Mw(A)X(A)+OH(B)Mw(B)X(B)Formula(I)where OH(A) represents an average number of hydroxyl groups in one molecule of the polyglycerol compound, Mw(A) represents a weight-average molecular weight of the polyglycerol compound, X(A) represents a content of the polyglycerol compound in the conductive pattern forming ink in weight percent; and OH(B) represents a number of hydroxyl groups in one molecule of the galactitol, Mw(B) represents a molecular weight of the galactitol, and X(B) represents a content of the galactitol in the conductive pattern forming ink in weight percent.

The present invention provides an efficient method of synthesizing and purifying dianhydrohexitols such as dianhydrogalactitol. In general, as applied to dianhydrogalactitol, the method comprises: (1) reacting dulcitol with a concentrated solution of hydrobromic acid at a temperature of about 80° C. to produce dibromogalactitol; (2) reacting the dibromogalactitol with potassium carbonate in t-butanol to produce dianhydrogalactitol; and (3) purifying the dianhydrogalactitol using a slurry of ethyl ether to produce purified dianhydrogalactitol. Another method produces dianhydrogalactitol from dulcitol; this method comprises: (1) reacting dulcitol with a reactant to convert the 1,6-hydroxy groups of dulcitol to an effective leaving group to generate an intermediate; and (2) reacting the intermediate with an inorganic weak base to produce dianhydrogalactitol through an intramolecular SN2 reaction. Other methods for the synthesis of dianhydrogalactitol from dulcitol are described.

A polyester copolymer, having a number average molecular weight of equal to or more than 4000 grams / mole and having a glass transition temperature of less than 160 DEG C, containing: (a) in the rangefrom equal to or more than 45 mole % to equal to or less than 50 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more bicyclic diol monomer units,wherein such one or more bicyclic diol monomer units is / are derived from one or more bicyclic diols chosen from the group consisting of isosorbide, isoidide, isomannide, 2,3:4,5-di-O-methylene-galactitol and 2,4:3,5-di-O-methylene-D-mannitol; (b) in the range from equal to or more than 25 mole % to equal to or less than 49.9 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of an oxalate monomer unit; (c) in the range from equal to or more than 0.1 mole % to equal to or less than 25 mole %, based on the total amount of moles of monomer units within the polyester copolymer, of one or more linear C3-C12 dicarboxylate monomer units; and (d) optionally equal to or more than 0 mole % to equal to or less than 5 mole %, based on the total amount of molesof monomer units within the polyester copolymer, of one or more additional monomer units. A process for producing such a polyester copolymer, a composition containing such polyester copolymer, a method for manufacturing an article comprising the use of one or more of such polyester copolymers and an article obtained or obtainable by such a method.

The present invention provides an efficient method of synthesizing and purifying dianhydrohexitols such as dianhydrogalactitol. In general, as applied to dianhydrogalactitol, the method comprises: (1) reacting dulcitol with a concentrated solution of hydrobromic acid at a temperature of about 80° C. to produce dibromogalactitol; (2) reacting the dibromogalactitol with potassium carbonate in t-butanol to produce dianhydrogalactitol; and (3) purifying the dianhydrogalactitol using a slurry of ethyl ether to produce purified dianhydrogalactitol. Another method produces dianhydrogalactitol from dulcitol; this method comprises: (1) reacting dulcitol with a reactant to convert the 1,6-hydroxy groups of dulcitol to an effective leaving group to generate an intermediate; and (2) reacting the intermediate with an inorganic weak base to produce dianhydrogalactitol through an intramolecular SN2 reaction. Other methods for the synthesis of dianhydrogalactitol from dulcitol are described.

The invention discloses a blueberry jelly-filled candy, which comprises a candy skin and a candy center wrapped by the candy skin. Sugar center includes: xylitol, sorbitol, blueberry anthocyanin extract; sugar skin includes: granulated sugar, fructose syrup, blueberry juice, raspberry juice, sorbitol, mannitol, xylitol, isomalt, One or several kinds of galactitol compound, gelatin, pectin, V C , Vitamin B 1 , vitamin D 3 . The candy adds new taste and new flavor of the sandwich candy, and adds effects of understanding alcohol, protecting the liver, anti-cancer and weight loss to the sandwich candy. The candy preparation process adopts ultra-high pressure and low-temperature sterilization, which reduces the activity loss of active substances such as blueberry anthocyanins and raspberry flavonoids caused by temperature rise, and at the same time combines pectin with anthocyanin molecules to improve the stability of anthocyanins. The invention is of great significance for enriching the types of berry products, prolonging the industrial chain of berry processing, increasing the added value of berries and promoting industrial development.

The invention provides a method for co-producing D-tagatose, arabitol and galactitol and an application, and belongs to the technical field of biological engineering. According to the invention, a genetically engineered bacterium E.coli BL21 / beta-gal-L-AI is utilized to convert whey so as to prepare the D-tagatose; and then the D-arabitol and the galactitol are produced by using byproducts generated in the preparation process of fermenting the D-tagatose by using the Metschnikowia pulcherrima, so as to finally realize efficient co-production of the D-tagatose, the D-arabitol and the galactitol.

A polyester including at least one furandicarboxylate unit, at least one saturated, linear or branched, diol unit including from 2 to 10 carbon atoms, and at least one bicyclic diol unit, the said bicyclic diol being chosen from: isosorbide, isoidide, isomannide, 2,3:4,5-di-O-methylene-galactitol, and 2,4:3,5-di-O-methylene-D-mannitol. The glass transition temperature of the polyester is greater than or equal to 90° C. Processes for preparing this polyester are also described.

The invention discloses recombinant escherichia coli for overexpression of a GatA gene and application thereof, and belongs to the technical field of genetic engineering and microbial engineering. According to the recombinant escherichia coli, the gatA gene of the specific IIA component of galactitol is used as a target gene, and the escherichia coli is used as an expression host, so that escherichia coli engineering bacteria which can be widely applied to preparation of medicines, feeds and chemicals are successfully constructed. The itaconic acid stress resistance of the escherichia coli engineering bacteria is remarkably improved and is increased by 29.4 times to the maximum compared with that of a wild strain, and the Dlactic acid stress resistance of the escherichia coli engineering bacteria is remarkably improved and is increased by 101 times to the maximum compared with that of the wild strain. The succinic acid stress resistance of the escherichia coli engineering bacteria is remarkably improved and is improved by 1.6 times to the maximum compared with that of the wild strain.

The invention discloses immobilized sorbitol dehydrogenase as well as an immobilization method and application of immobilized sorbitol dehydrogenase. A mesoporous material SBA15 with an adaptive pore diameter is used as a carrier and free sorbitol dehydrogenase is immobilized under a proper pH (Potential of Hydrogen) condition to obtain immobilized enzyme of the sorbitol dehydrogenase; and the prepared immobilized sorbitol dehydrogenase is used as a catalyst, and 20U-300U of NADH (Nicotinamide Adenine Dinucleotide Hydrogen) oxidase and 0.05mmol / L-0.5mmol / L of NAD<+> are added under the conditions that the concentration of a primer (sorbitol or D-galactitol or L-iditol) is 1.5g / L-100g / L and react for 3h-12h under the conditions that the pH is 8.0-9.0, the temperature is 20 DEG C-30 DEG C and the speed is 180rpm-280rpm, so as to obtain D-fructose (or D-tagatose or L-sorbose); after reaction is finished, a solution is filtered and the sorbitol dehydrogenase is recycled; and 75% of catalytic activity can still be kept after the sorbitol dehydrogenase is repeatedly used for 5 times. According to the immobilized sorbitol dehydrogenase disclosed by the invention, immobilization condition optimization is carried out through computer simulation, the immobilization efficiency is high and the protein supporting quantity reaches 545mg / g.