The invention belongs to the technical field of preparation of
galactitol, and particularly relates to a method for preparing
galactitol by taking
lactose as a
raw material. Comprising the following steps: S1, preparation of an adsorption column: preparing
phenylboronic acid polymer microspheres and packing the microspheres into a column to obtain the adsorption column; s2, enzymolysis: carrying out enzymolysis on the
lactose solution through
lactase to obtain enzymatic
hydrolysate; s3,
monosaccharide separation: filtering the enzymatic
hydrolysate, adjusting the pH value to be alkaline, passing through an adsorption column to obtain a glucose-rich solution, and enabling an eluent to flow through the adsorption column to obtain a
galactose-rich solution; and S4, hydrogenation: carrying out
ion exchange, concentration, hydrogenation, decoloration,
ion exchange, concentration and
crystallization on the
galactose pregnant solution to obtain
galactitol. According to the invention,
galactose with a cis-
vicinal diol structure can be adsorbed by the
phenylboronic acid polymer carrier, so that glucose and galactose which are difficult to separate by
chromatographic separation are separated, and a production process for preparing galactitol by taking
lactose as a
raw material is realized.