114 results about "Acute diarrhea" patented technology

A composition containing at least one polyol and certain amounts of inulin relative to the at least one polyol, characterized by a reduced tendency of the at least one polyol to induce acute diarrhea. The at least one polyol may be, for example: xylitol, sorbitol, maltitol, mannitol, isomalt, isomaltitol, lactitol, hydrogenated starch hydrolysates (HSH), glycerol, propylene glycol, erythritol, galactitol and combinations thereof. The composition also contains inulin in amounts sufficient to at least partially reduce, or eliminate, the tendency of the polyol to induce acute diarrhea. Foodstuffs, including drinks and beverages, contain said compositions.

A Chinese medicine in the form of pill for treating the gastrointestinal diseases, especially the acute diarrhea and intestinal irritable syndrome, is prepared from 10 Chinese-medicinal materials including jujube, musk, rhubarb, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.

An application of the montmorillonite nanoparticles in preparing the medicine for treating the ulcer in digestive tract, regurgitation of stomach and esophagus, esophagitis, gastritis, colitis, acute diarrhea, chronic atrophic gastritis is disclosed. Its composite medicine is also disclosed.

The present invention relates to a novel strain enabling inhibition of rotavirus that is known as a principal cause of acute diarrhea and enteritis in children and in the young animals of cattle, horses, pigs and monkeys, etc, and an active protein also having an anti-rotavirus activity produced from the same.

The novel strain of the present invention was named as Bifidobacterium longum AR81 (KCCM-10492). The novel strain of the present invention and the active protein separated from the same can be effectively used for the production of medicine for intestinal disorders and especially for the production of baby goods.

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from elecampane, agilawood, fructus aurantii, sandalwood, rheum officinale, mangnolia officinalis, Muscat and defatted croton seed powder mixed with other medicaments. The invention is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like in clinic.

The invention relates to a preparation method of racemic N-[2-acetyl mercapto) methyl]-1-oxygen-3-phenyl propyl] glycine benzyl ester (racecadotril), which is essentially prepared by amidation reaction of 2-benzyl-3-thio-acetyl propionyl halide and glycine benzyl ester salt or glycine benzyl ester. Compared with the prior art, the invention has short reaction process, high yield. The prepared racecadotril is mainly used for the treatment of acute diarrhea for adults and children.

The present invention discloses one coding gene of rotavirus VP6 protein and its application, and aims at providing one coding gene of rotavirus VP6 protein with high expression amount in dicotyledonous plant, especially clover, method of producing oral rotavirus vaccine with the coding gene and the obtained oral vaccine. The rotavirus VP6 protein coding gene has one of the following nucleotide sequences: 1. DNA sequence of SEQ ID No. 1 in the sequence list; 2. DNA sequence of SEQ ID No. 2 in the sequence list; 3. the nucleotide sequence capable of hybridizing in high strict condition with the DNA sequence limited by SEQ ID No. 1 or SEQ ID No. 2; and 4. DNA sequence possessing over 80 % homology with the SEQ ID No. 1 or SEQ ID No. 2 limited DNA sequence and high expression amount in dicotyledonous plant. The oral rotavirus vaccine is used in preventing various rotavirus infection caused acute diarrhea of infant and young animal.

The invention relates to a sandalwood-containing traditional Chinese medicine for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine is prepared by processing ten drugs such as costustoot, sandalwood, immature bitter orange, fructus amomi, rhizoma coptidis or radix scutellariae, mangnolia officinalis or rhizoma atractylodis, muskiness, defatted croton seed powder, Chinese date and ligusticum wallichii and the like, is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like on clinic.

The invention discloses a drug capsule to cure intestines disease and sinusitis, and the preparing method, using Common Andrographis Herb and Climbing Groundsel Herb as main raw material, associated with micronized silica gel. It is applied to symptoms such as enteritis, colonitis, bacteroidal dysentery and sinusitis, has better curative effect on the patient suffering sinusitis whose course of diseases is short and whose middle nose channel have no rhinopolypus, has good curative effect on the patient suffering from acute diarrhea, acute dysentery and acute enteritis, especially the patient taking other medicine to cause maladjustment of bacteric crowd to produce side-effect. It has functions of cleaning heat and detoxifying, diminishing inflammation and acesodyne, and anti-diarrhoea. It better preserves effective substance in medicinal materials, shelf life up to above two years and having advantages of good stability, accurate curative effect, saving time, low cost, etc.

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from elecampane, pericarpium citri reticulatae viride or rhizoma cyperi, fructus aurantii, sandalwood, rheum officinale, mangnolia officinalis, muscat, defatted croton seed powder, fructus Zizyphi and ligusticum wallichii. The invention is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like in clinic.

Campylobacter jejuni is a leading cause of bacterial food-borne diseases in humans, ranging from acute diarrheal disease to neurological disorders. An isolated or purified antibody or fragment thereof specific to C. jejuni is described. The antibody or fragment thereof binds to a flagellar protein and reduces motility of C. jejuni. The antibody or fragment thereof is derived from a heavy chain IgG variable domain fragment (VHH) of a camelid animal immunized with C. jejuni flagellar protein. A multivalent form, as well as a phage format, of the antibody or fragment thereof is described. Methods of reducing presence of C. jejuni in an animal or an animal environment, methods and formulations for treating C. jejuni infection, and method of detecting C. jejuni are also described.

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine composition is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.

The invention relates to a traditional Chinese medicine patch for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine patch is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine patch is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.

The invention discloses a dual detection box of rotavirus and adenovirus and comprises test objects and feces diluents; wherein, the test objects consist of chromatographic films and water absorbent materials and comprise a first area, a second area, a third area and a fourth area; the first area comprises an absorbent pad made of water absorbent materials and used for initial sampling contact; the second area comprises latex particles which are coated by monoclonal antibodies of the rotavirus and adenovirus; the third area comprises three lateral parallel chromatographic films which can not be seen with naked eyes, and a first film is provided with a specific anti-adenovirus antibody, and a second film is provided with a specific anti-rotavirus antibody and a third film is a quality control line; the fourth area comprises an absorbent pad made of the water absorbent materials. The detection box is convenient in use and can be used for detecting the acute diarrhea, vomiting, high fever and stomachache which are caused by viral gastroenteritis of adults and infants with less time, labor and materials.

The invention provides a reagent kit for detecting porcine delta coronaviruses and acute diarrhea syndrome coronaviruses porcine delta coronavirus. According to a primer and probe (SEQ ID NO: 1-6) fordouble real-time fluorescent quantitative PCR detection of the porcine delta coronaviruses and the porcine acute diarrhea syndrome coronaviruses, and a double real-time fluorescent quantitative PCR detection method established based on the primer and the probe, and rapid identification and detection of the two viruses in one reaction can be realized at the same time. The reagent kit can completedetection within 2 hours, has the advantages of quickness, specificity, sensitivity, high flux and the like, and can meet the requirements of quickly identifying and detecting the porcine delta coronaviruses and the porcine acute diarrhea syndrome coronaviruses on a large scale.

The invention belongs to the field of nucleic acid detection and diagnosis, and in particular relates to a loop-mediated isothermal amplification (LAMP) primer composition and kit for detecting a swine acute diarrhea syndrome coronavirus (SADS-CoV) by using a microfluidic chip technology. In order to solve the defect of time-consuming, laborious and high-cost detection of a swine acute diarrhea syndrome coronavirus, LAMP primers are designed according to a relatively conservative M gene of the SADS-CoV, after screening is performed, the LAMP primer composition for detecting the swine acute diarrhea syndrome coronavirus is obtained. The invention also provides the kit combining the microfluidic chip technology and an LAMP technology and a detection method of the SADS-CoV by using the kit. The composition and kit are applied to detection of the swine acute diarrhea syndrome coronavirus, and can realize the rapid and immediate detection of the swine acute diarrhea syndrome coronavirus, thereby solving the defect of time-consuming, laborious and high-cost detection of the swine acute diarrhea syndrome coronavirus; and the composition and kit improve the detection sensitivity and specificity, reduce labor and equipment costs, and shorten the detection cycle.

The invention discloses a medicament for treating acute diarrhea. A preparation method for the medicament comprises the following steps of: decocting chicken gizzard membrane, plantain seed, oriental waterplantain rhizome, pawpaw, figwort flower picrorhiza rhizome and liquoric root which serve as raw materials over slow fire repeatedly, concentrating a liquid medicine into thick paste, and adding the conventional excipient into the thick paste to prepare clinically acceptable tablets, capsules, pills, granules, powder, injection or paste. The medicament can treat all types of acute diarrhea.

The invention provides application of a traditional Chinese medicinal composition in the preparation of a medicine for treating diarrhea. The medicine is prepared from the following raw materials (byweight): 120-360 parts of Astragalus membranaceus, 100-300 parts of ligustrum lucidum ait, 30-95 parts of ginseng, 30-95 parts of lucid ganoderma, 65-195 parts of curcuma zedoary, 30-90 parts of bighead atractylodes rhizome, 65-195 parts of scutellaria barbata, 120-360 parts of gynostemma pentaphyllum, 30-95 parts of Poria cocos, 15-45 parts of endothelium corneum gigeriae galli, 65-195 parts of indian mockstrawberry herb, 65-195 parts of solanum lyratum, 65-195 parts of herba artemisiae scopariae, 65-195 parts of radix cynanchi panicullati, 10-30 parts of ground beeltle, and 65-195 parts of Hedyotis diffusa. The diarrhea treated by the medicine is acute diarrhea, chronic diarrhea and diarrhea caused by tumor chemotherapy.

The invention belongs to the technical field of biology, and particularly relates to a double-antibody sandwich ELISA kit for detecting porcine acute diarrhea syndrome coronavirus. The double-antibody sandwich ELISA kit for detecting the porcine acute diarrhea syndrome coronavirus comprises an ELISA plate coated with a rabbit anti-SADS-CoV N protein polyclonal antibody, and an HRP (horse radish peroxidase) labeled mouse anti-SADS-CoV N protein monoclonal antibody. The kit further comprises an enzyme-labeled secondary antibody, a confining liquid, a diluent, a washing liquid, a developing liquid and a stop solution. The double-antibody sandwich ELISA kit established by the invention has relatively good specificity, sensitivity and intra-batch and inter-batch repeatability. The lowest virus detection amount of the kit is 10-4.42TCID50/0.1 mL, the kit does not react with PEDV, TGEV and PDCoV, and the intra-batch and inter-batch repeated variable coefficient is less than 10%. Compared with an RT-PCR (Reverse Transcription-Polymerase Chain Reaction) method, the detection coincidence rate of the double-antibody sandwich ELISA kit disclosed by the invention is 93.93%. The SADS-CoV antigen double-antibody sandwich ELISA detection method established by the invention has good sensitivity, specificity and repeatability, and can be used for clinical detection of SADS-CoV.