The cepharanthine dripping pill containing cepharanthine 1-10 mg and proper amount of dripping pill medium in each pill. The dripping pill medium is one or two of polyglycol-6000, polyglycol-4000, polyoxyethylene monostearate, sodium stearate, glycerin, gelatin, poloxamer, stearic acid, glycerin monostearate and insect wax. The preparation process of the cepharanthine dripping pill includes melting and mixing cepharanthine and dripping pill medium, dropping at 60-100 deg.c into condensating agent, and eliminating condensating agent. The condensating agent is one or two of dimethyl silicon oil, liquid paraffin, tea seed oil and rape seed oil. The cepharanthine dripping pill is white or slight yellow and bitter. The cepharanthine dripping pill is used in treating chemotherapy caused leucopenia, and has the features of less side effect, low dosage, high medicinal effect, etc.