48 results about "Leukocytopenia" patented technology

The invention discloses the use of ursane type triterpenoid saponin in preparing medicine for increasing leucocyte and / or platelet which has a general formula (I), the invention also provides a pharmaceutical composition having the action of increasing human leucocyte and / or platelet, which contains ursane type triterpenoid saponin composition having a general formula (I), and pharmaceutically acceptable salts.

A Chinese medicine in the form of table, capsule, particle, powder, pill, etc for treating aplastic anemia, iron-deficiency anemia, and leukocytopenia is prepared from 21 Chinese-medicinal materials including donkey-hide gelatin, Chinese angelica root, astragalus root, mother wort, etc. Its advantage is high curative effect.

A Chinese medicine in the form of oral liquid for treating senile weakness, a sexuality, impotence, ejaculation praecox and leukocytopenia is prepared from 20 Chinese-medicinal materials including pilose antler, American ginseng, ginseng, astragalus root, etc through soaking 5 of them in alcohol, filtering, concentrating; decocting others twice, filtering, concentrating; mixing them together, adding cane sugar or honey, stirring and sterilizing.

A blood-nourishing compound donkey-hide gelatin paste is prepared from 13 Chinese-medicinal materials including donkey-hide gelatin, fleece flower root, Chinese angelica root, wolfberry fruit, etc. It can be used to treat leukocytopenia and anemia. Its advantages are high curative effect, and no toxic by-effect.

The invention relates to a sanguisorba root general saponin extract, method for preparation and use thereof, characterized in that, a sanguisorba root general saponin extract is provided which contains sanguisorba root general saponin, the percentage by weight is 10-90%, it can be utilized in the preparation of medicinal preparation for treating or preventing human leucocytopenia. The beneficial effects of the invention are, the preparation can be made into multiple doses including oral, tablet and capsule, and it is adapted for leucocytopenia of unknown reasons.

The invention discloses a Chinese medicinal composition for treating malignant tumor, belonging to the field of Chinese medicines. The Chinese medicinal composition is a medicament preparation formed from herba oldenlandiae, astragalus root, tuckahoe, prepared pinellia tuber, herba scutellariae barbatae, teloon, scorpion, scolopendra and the like by adopting advanced processes including extraction with water, extraction with ethanol, enzymolysis of trypsinase and the like according to a certain compatible requirement, and the medicament preparation is preferably prepared into capsules and tablets. The Chinese medicinal composition has a certain function for relieving symptoms for lung cancer, liver cancer, gastric cancer, intestinal cancer, breast cancer, encephaloma, lymph cancer and other malignant tumors, reducing tumor bodies, inhibiting the growth of the tumors and the like; and according to the Chinese medicinal composition, the human immune capability can be improved, the lives of patients suffered from tumors can be prolonged and the adverse reactions of leukocytopenia, dizzy, weakness and fatigue, skinniness, poor appetite, nausea and vomiting and the like due to radiotherapy chemotherapy for cancers can be effectively relieved.

The invention discloses an oral medicine for preventing and treating leukocytopenia caused by chemotherapy, which is prepared from the following traditional Chinese medicines in parts by weight: 2-3 parts of herba epimedii, 1-2 parts of psoralea, 2-3 parts of astragalus root, 1-2 parts of sun-dried ginseng, 1-2 parts of bighead atractylodes rhizome, 2-3 parts of poria cocos, 1- 2 parts of prepared licorice, 1-2 parts of angelica, 1-2 parts of chuanxiong rhizome, 1-2 parts of red peony root, 1-2 parts of prepared rehmannia root, 1-2 parts of donkey-hide gelatin, 2-3 parts of spatholobus stem, -3 parts of rhizoma polygonati, 1-2 parts of chickens gizzard-membrane, 1-2 parts of fried malt, 1-1.5 parts of pinellia tuber and 1-1.5 parts of dried orange peel. The donkey-hide gelatin can be replaced by 0.5-1 part of antler glue. The oral medicine provided by the invention is a decoction, or can be prepared into an oral liquid, granules, a fluid extract or pill according to traditional methods. The oral medicine provided by the invention can be used for preventing and treating leukocytopenia caused by chemotherapy and can also be used for preventing and treating leukocytopenia caused by various other factors.

A Chinese medicine in the form of capsule for treating leukocytopenia, dizziness, cold, etc is prepared from 7 Chinese-medicinal materials including jujube, donkey-hide gelatin, astragalus root, Chinese angelica root, etc. Its advantages are high curative effect and no toxic by-effect.

A Chinese medicine in the form of capsule for nourishing blood, and treating leukocytopenia, wheakness, insomnia, palpitation, etc is prepared from 7 Chinese-medicinal materials including fleece flower root, mulberry fruit, astragalus root, white peony root, etc. through decocting twice, filtering, concentrating, drying, pulverizing and loading in capsules.

The invention discloses a compound shown by formula I, or usage of salt or ester which can be acceptable thereby on pharmacology, namely, a composition used for preparing medicine that can control and treat leukocytopenia. The invention also discloses the usage on controlling and treating immunological suppression.

The present invention relates to a preparation method of cepharanthine hydrochloride, which discloses a purification and synthesis process of cepharanthine hydrochloride. The method is simple and controllable, and saves energy source. The prepared cepharanthine hydrochloride has reliable quality and high bioavailability, can remarkably relieve chemotherapy and radiotherapy-induced leukocytopenia of patients with malignant tumors, and has good application prospects.

An improved Chinese medicine 'Qijiao Shengbai granule' for treating dizziness, night sweat, leukocytopenia, etc is prepared through extracting in alcohol and decocting for part of raw materials, direct decocting for part of raw materials, collecting volatile oil and decocting for part of raw materials, pulverizing the rest, granulating, adding additive and volatile oil, and granulating again. Its advantages are high curative effect and high safety.

The invention relates to a preparation of traditional Chinese medicine decoction pieces, and particularly relates to a leukocyte-increasing traditional Chinese medicine decoction piece combined preparation as well as a preparation method and a combined package thereof. The preparation is prepared from the following raw materials in parts by weight: 10-15 parts of epimedium, 10-15 parts of fructus psoraleae, 5-10 parts of radix aconiti carmichaeli, 5-10 parts of fructus lycii, 5-10 parts of astragalus membranaceus, 3-8 parts of suberect spatholobus stem, 3-5 parts of rubia cordifolia, 3-5 parts of angelica sinensis, 1-3 parts of rhizoma phragmitis, 1-3 parts of radix ophiopogonis and 1-3 parts of licorice root. The preparation has the effects of warming kidneys and strengthening spleen, tonifying qi and blood, is used for treating patients with leukocytopenia due to spleen-kidney yang deficiency and qi-blood deficiency caused by cancer radiotherapy and chemotherapy, wherein leukocytopenia due to spleen-kidney yang deficiency and qi-blood deficiency has the syndromes of exhaust and fatigue, lack of energy, extreme chilliness, poor appetite and loose stool, soreness and weakness of waist and knees and the like. The preparation is capable of effectively increasing the content of leukocyte in blood, reducing the toxic and side effect of chemotherapy, and effectively improving the living quality of tumor patients.

A Chinese medicine for treating the leukocytopenia caused by radiotherapy or chemicotherapy, aplastic anemia and iron-deficiency anemia is prepared from 7 Chinese-medicinal materials including mulberry fruit, fleece flower root, white peony root, astragalus root, etc.

An auxiliary anticancer medicine for increasing the curative effect of other anticancer medicines, decreasing their toxic, and preventing and treating the leukocytopenia caused by radiotherapy or chemicotherapy features that its active component is 20(s)-ginsenoside-Rg3. It is applied by injection or oral taking.

The present invention relates to a preparation method of cepharanthine hydrochloride, which discloses a purification and synthesis process of cepharanthine hydrochloride. The method is simple and controllable, and saves energy source. The prepared cepharanthine hydrochloride has reliable quality and high bioavailability, can remarkably relieve chemotherapy and radiotherapy-induced leukocytopenia of patients with malignant tumors, and has good application prospects.

The invention discloses a Chinese materia medica preparation for treating leukocytopenia and a preparation process thereof and belongs to the technical field of drugs. The Chinese materia medica preparation is prepared by the following raw materials, by weight, of 10-40% of astragalus mongholicus, 5-40% of angelica sinensis, 5-30% of fructus ligustri lucidi, 5-30% of caulis spatholobi, 5-30% of the root of red-rooted salvia, 5-30% of monkshood, 5-30% of the fruit of Chinese wolfberry and 5-30% of fructus psoraleae. Raw medicinal materials of the Chinese materia medica preparation is a pure Chinese materia medica preparation, clinical market effects are obvious and safe, and pharmacodynamic effects of the leukocytopenia caused by radiotherapy and chemotherapy of tumour patients are obvious. The Chinese materia medica preparation is simple in process, stable in quality, controllable in cost and suitable to industrial production.

A Chinese medicine 'Shengxuebao pill' for treating the leukocytopenia caused by chemicotherapy, dizziness, tinnitus, insomnia, palpitation, etc is an improvement to existing relative medicine in the form of particles. Its preparing process is also disclosed. Its advantages are high curative effect, high release speed, and high biologic utilization rate.

A composite Chinese medicine in the form of concentrated liquid for treating leukocytopenia is prepared from astragalus root, mulberry fruit, Chinese angelica root and ganoderma. Its preparing process is also disclosed.

A Chinese medicine for promoting the regeneration of white cell and treating the leukocytopenia caused by chemicotherphy or radiotherapy is prepared from ginseng, atractylodes rhizome, rice vinegar and green alum through baking and pulverizing ginseng and atractylodes rhizome to obtain particles less than 120 meshes, mixing, calcining and pulverizing others to obtain particles less than 12 meshes, and mixing. Its advantages are high curative effect and no toxic by-effect.

A dispersing tablet of sanguisorba root for treating leukocytopenia is prepared from fine powder of sanguisorba root and the auxilairies chosen from lactose, mannitol, calcium sulfate, starch, xylitol, microcrystalline cellulose, low-substituted hydroxypropyl cellulose, cross-linked povidone, carboxymethyl starch sodium, carboxymethyl cellulose sodium, povidone K30 and superfine silica gel powder.

The invention discloses a purpose of a triterpene substance. The triterpene substance is one compound or more compounds or pharmaceutically acceptable salts or esters as the formula I, wherein R1 is selected from glucosyl group, glucose (1-2) glucose, glucose (1-4) glucose, or (2'-OSO3H) glucose; R2 is hydroxyl group, alcohol group or hydrogen atom; R3 is alkyl, carboxyl, alcohol group or COOGlu;R4 is alkyl or carboxyl; R5 is alkyl; and R6 is carboxyl or hydrogen atom. The triterpene substance can be used for preparing a compound preventing and curing leukocytopenia.

The invention discloses a pharmaceutical composition for treating leukocytopenia and immune hypofunction caused by radiotherapy and chemotherapy and a preparation method of oral granules of the pharmaceutical composition. The pharmaceutical composition is characterized in that the pharmaceutical composition comprises the following raw materials in parts by weight: 20 parts of rhizoma polygonati, 5 parts of ginseng, 5 parts of hericium erinaceus, 10 parts of palmleaf raspberry fruits, 10 parts of angelica sinensis, 10 parts of sanguisorba officinalis, 10 parts of fructus ligustri lucidi, 10 parts of jujube, 10 parts of peanut coats and 10 parts of pericarpium citri reticulatae. Systematic observations on clinical and scientific research cases show that the pharmaceutical composition has the effects of replenishing qi to invigorate the spleen, nourishing yin and enriching essence, enriching the blood and invigorating the circulation of blood, and has an ideal therapeutic effect on both qi-yin deficiency type leukocytopenia and immune hypofunction caused by radiotherapy and chemotherapy.

The invention discloses a traditional Chinese medicine prescription for oral administration for treating leukopenia. 10 grams, 15 grams of Atractylodes macrocephala, 10 grams of medlar, 10 grams of angelica, 20 grams of astragalus, and 15 grams of Codonopsis. 1 dose per day, 3 times a day, 2 weeks as a course of treatment. The present invention treats leukopenia, and the effect is remarkable, and the drug effect is long-lasting, and there is no adverse reaction and side effect.

An auxiliary anticancer medicine for increasing the curative effect of other anticancer medicines, dicreasing their toxin, and preventing and treating the leukocytopenia caused by radiotherapy and chemicotherapy by injection or cral application features that its active component is protopanoxatriol.

A blood-nourishing compound donkey-hide gelatin paste is prepared from 13 Chinese-medicinal materials including donkey-hide gelatin, fleece flower root, Chinese angelica root, wolfberry fruit, etc. It can be used to treat leukocytopenia and anemia. Its advantages are high curative effect, and no toxic by-effect.

The invention relates to a calcium folinate drug composition freeze-dried powder injection for treating leukocytopenia, and belongs to the technical field of medicines. The calcium folinate drug composition freeze-dried powder injection comprises calcium folinate and an excipient, wherein the excipient is low molecular dextran; calcium folinate is a novel crystal compound which is different from that reported in the prior art, and the X-ray powder diffraction pattern obtained through measurement by using Cu-K-alpha rays is as shown in the figure 1. Experiments show that compared with the prior, the calcium folinate crystal compound provided by the invention, is lower in impurity content, better in stability, and obviously improved in solubility in water and mobility, solves the problems in the prior art that calcium folinate is poor in solubility, poor in stability and high in content of related substances, provides convenience for preparation of preparations, and greatly improves the curative effect; besides, the freeze-dried powder injection prepared by utilizing the novel crystal compound is good in re-dissolution, good in stability, good in stability after being compounded with a solvent, extremely low in content of insoluble particles and particularly suitable for clinical application.

The invention provides a weakness symptom improving traditional Chinese medicinal composition, a medicine, and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The weakness symptom improving traditional Chinese medicinal composition is prepared from the following main components: human placenta, ginseng, astragalus membranaceus, radix polygonati officinalis, antler, donkey-hide gelatin and the like. The weakness symptom improving traditional Chinese medicinal composition has the efficacies of tonifying Qi, strengthening the vital essence, benefiting Qi, nourishing blood and nourishing liver and kidney, can improve weakness symptoms, such as low immune function, mental fatigue, palpitation, forgetfulness, aching and limp waist and knees, thin and weak pulse and the like, caused by Qi deficiency, blood deficiency, liver deficiency and kidney deficiency very well, and has a good auxiliary therapeutic effect on high blood pressure, high blood lipid and diabetes caused by Qi deficiency, blood deficiency, liver deficiency and kidney deficiency as well as leukocytopenia or granulocytopenia and other symptoms after radiochemotherapy.

An injection of kurarinol for treating chronic hepatitis and leukocytopenia is prepared from kurarinol through depositing in water, cold storage, ultrafiltration, further preparing in dark condition and N2 atmosphere, pouring in containers, sterilizing and lamp examining.