703 results about "Resveratrol" patented technology

The invention provides a personalized functional nutritional tea point rich in tea polyphenol and resveratrol and a 3D printing manufacturing method. The personalized functional nutritional tea point comprises a shell and an inner core, wherein the shell and the inner core are respectively a shell gel material and an inner core gel material; the inner core gel material comprises a water-oil double-gel material rich in tea polyphenol and resveratrol; wherein the water-oil double-gel material is prepared by the following steps: adding chitosan, betaine and vanillin into a mixed solution of corn starch, chickpea protein and water, heating and incubating to obtain hydrogel; and dissolving the tea polyphenol in the hydrogel to obtain the tea polyphenol hydrogel. The oleogel is obtained by melting and mixing beeswax and linseed oil, and then dissolving resveratrol in the oleogel; the personalized functional nutritional tea point is high in content of active ingredients of tea polyphenol and resveratrol and has heat stability, illumination stability and storage stability; the 3D coaxial printing technology is utilized, the functional components are further stabilized, tea points of various patterns and shapes can be obtained, and the method has personalized food preparation and application value.

The invention relates to the technical field of pharmaceutical preparations, and discloses a composition with liver protection and antioxidation effects and a preparation method thereof.The composition is prepared from galactosamine modified astragalus membranaceus exosome, schisandra chinensis nanocrystals, liquorice-chitosan nanoparticles, lactobacillus acidophilus freeze-dried powder, beta-(1, 3) / (1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate) sourced from saccharomyces cerevisiae, and beta-(1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate). And (6) a dextran, grape exosome-curcumin hybrid vesicle freeze-dried powder, a curcumin-mitochondrial targeting peptide compound, a resveratrol-hydroxypropyl-beta-cyclodextrin inclusion compound and reduced panthenol. According to the liver-protecting and anti-oxidation composition disclosed by the invention, multi-dimensional intervention on liver protection is realized through an elaborately designed ternary system. The system is composed of a traditional Chinese medicine extract, a microorganism-plant exosome combination and a high-bioavailability antioxidant, all the parts have a synergistic effect, and the liver protection effect is remarkably improved.

The invention belongs to the technical field of biology, and discloses a stable protective agent, a cell antigen dry sheet and a preparation method and application of the dry sheet, the stable protective agent comprises glycerin with the volume fraction being 0.4%, gelatin with the mass volume fraction being 0.1%, EDTA with the mass volume fraction being 0.1 mM, trehalose with the mass volume fraction being 0.03% and resveratrol with the mass volume fraction being 100 [mu] M. The stable protective agent is adopted for preparing the cell antigen dry sheet, and the cell antigen dry sheet is applied to CBA detection. The stable protective agent has good permeability, can penetrate through cell membranes to enter cells, provides a protection effect inside and outside the cells, has moisture retention and oxidation resistance, can prevent cell deformation and cell fixing layer shedding, and can well maintain the stability and reliability of antigen proteins, and the prepared cell antigen dry sheet can be stored for a long time, and has a good application prospect. The antigenicity of a membrane signal index is not damaged. When a positive sample is detected, obvious green fluorescence cells can be seen, red fluorescence quenching is avoided, and co-localization of red fluorescence and green fluorescence can be observed conveniently.

The invention provides a composition for promoting hair regeneration after chemotherapy as well as a preparation method and application thereof, and belongs to the technical field of medicines. The preparation method comprises the following steps: modifying the surface of a gold nanocage with polydopamine, loading the modified gold nanocage on an exosome, complexing magnesium ions and zinc ions to prepare a modified exosome, preparing a nano drug-loaded liposome from curcumin, resveratrol and epigallocatechin gallate, mixing the nano drug-loaded liposome with the modified exosome to prepare a multi-layer liposome, and preparing the multi-layer liposome from the nano drug-loaded liposome. And mixing with a penetration enhancer, and adding into a temperature-sensitive hydrogel system to prepare the composition for promoting hair regeneration after chemotherapy. The composition for promoting hair regeneration after chemotherapy has a good transdermal absorption promoting effect, can slowly release drugs, promotes hair follicles to be converted from a resting stage to a growing stage under the synergistic effect of the drugs, regulates and controls multiple pathways (such as anti-apoptosis, angiogenesis promotion and anti-inflammation) at the same time, is matched with a complex pathological mechanism of hair regeneration after chemotherapy, and can promote hair regeneration after chemotherapy. Wide application prospects are realized.

The invention relates to an oral mucosa repairing medicine and a preparation method thereof, and belongs to the technical field of medicines, the medicine comprises barnacle peptide, salivary lactobacillus, resveratrol, a biphasic adhesion matrix, hydroxyapatite, vitamin B family and other components. The preparation method comprises the following steps: sequentially carrying out enzymolysis on barnacle gooseneck by pepsin and lumbrukinase to obtain barnacle peptide. The double-phase adhesion matrix comprises a water-phase matrix, an oil-phase matrix and lecithin; the water-phase matrix contains a chondroitin sulfate-chitosan quaternary ammonium salt compound, sodium alginate and other components; the oil-phase matrix comprises sesame oil, beeswax, a polylactic acid-glycolic acid copolymer and the like. According to the invention, barnacle peptide and salivary lactobacillus are prepared by adopting a special method and are matched with resveratrol for use, so that multi-target and multi-path promotion of oral mucosa repair can be realized; the chondroitin sulfate-chitosan quaternary ammonium salt compound is prepared through electrostatic and physical embedding, the chondroitin sulfate-chitosan quaternary ammonium salt compound is matched with other components to prepare the biphasic adhesion matrix, the biocompatibility is good, the adhesion is high, and the action time of a sustained-release drug is well prolonged.

The invention belongs to the technical field of functional Pickering emulsion preparation, and particularly discloses a silk fibroin nanoparticle-stabilized biphase drug-loaded Pickering emulsion and an antibacterial application thereof. The curcumin-loaded silk fibroin nanoparticles Cur-SFNPs with uniform form and size are prepared by using an anti-solvent precipitation method. In order to improve the antibacterial effect of the Pickering emulsion, the Cur-SFNPs is utilized to stabilize the soybean oil loaded with resveratrol, and the oil-in-water type Pickering emulsion is prepared. The Pickering emulsion prepared by taking Cur-SFNPs as a stabilizer has the characteristics of small particle size, uniform distribution, storage stability, heating stability, freeze-thaw stability, food safety and environmental friendliness. And as a two-phase drug-loaded emulsion, two natural hydrophobic active drugs are loaded at the same time, so that the solubility and bioavailability of the emulsion can be enhanced, the loaded active substances play a synergistic antibacterial and antioxidant role, and the emulsion can be applied to food preservation.

The invention provides a gamma delta T cell preparation as well as a preparation method and application thereof, and belongs to the technical field of T cells. The liposome is prepared from the following raw materials in parts by weight: 15-20 parts of modified gamma delta T cell liposome, 1-3 parts of cell stimulating factors and 4-7 parts of culture medium freeze-dried powder, the modified gamma delta T cell lipidosome is prepared by embedding gamma delta T cells through lipidosome, coupling with acetylenic bond modified chitosan, and further mixing with MFAP4 protein and b4GALT1 protein. The culture medium freeze-dried powder is prepared by freeze-drying the culture medium in the engineering culture process of gamma delta T cells, and the cell stimulating factors are resveratrol and quercitrin. According to the gamma delta T cell preparation prepared by the invention, the survival ability and resistance of gamma delta T cells are improved, the anti-tumor activity of the gamma delta T cells is improved, and the gamma delta T cell preparation has relatively good antioxidant and anti-inflammatory effects, reduces the inhibition of inflammation on an immune system and has a very good treatment effect on pancreatic ductal adenocarcinoma.

The invention relates to the technical field of biology, in particular to a gene for increasing the content of resveratrol in grapes and application of the gene. The invention discloses a gene for improving the content of resveratrol in grapes. The DNA sequence of the gene is shown as SEQ ID NO1. The amino acid sequence of the gene synthetic protein disclosed by the invention is as shown in SEQ ID NO2, and the protein is named as VvFHY34D. According to the invention, when four amino acids S124, T128, S156 and T160 of the VvFHY3 are all replaced with aspartic acid to simulate phosphorylation activation, the VvSTS expression quantity in transient over-expression VvFHY34D grapes is higher, and more resveratrol can be synthesized.

The invention belongs to the technical field of cosmetics, and discloses skin-tightening and anti-wrinkle essence. The skin-tightening anti-wrinkle essence is prepared from the following raw materials in percentage by mass: 1.5 to 2.5 percent of acetyl hexapeptide-8, 2.0 to 3.0 percent of palmitoyl pentapeptide-4, 3.0 percent of hydroxypropyl tetrahydropyrantriol, 2.0 percent of lipidosome-coated vitamin C ethyl ether, 0.5 percent of resveratrol PLGA microspheres, 0.8 percent of ceramide NP, 1.2 percent of pachymaran, 5.0 percent of glyceryl polyether-26, 0.3 percent of sodium hyaluronate, 0.5 percent of p-hydroxyacetophenone and 1, 3-propanediol, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate and the balance of water. The 1, 2-hexanediol accounts for 0.6%, and the balance is deionized water. Multi-target anti-wrinkle, deep moisturizing and long-acting repairing are achieved by scientifically compounding active ingredients such as acetyl hexapeptide-8 and palmitoyl pentapeptide-4 and combining a lipidosome wrapping technology and a nano-microsphere slow release technology, the preparation process comprises the steps of lipidosome homogenization, nano-microsphere multiple emulsion method and low-temperature emulsification, the ingredient stability and transdermal efficiency are ensured, and the skin care effect is good. Experiments prove that the essence can significantly improve skin elasticity and reduce wrinkles, and has a significant anti-aging effect.

The present invention provides an enhanced NK cell, its preparation method and application, belonging to the field of biomedical technology. The present invention uses a compound of quercetin, paclitaxel and resveratrol as a culture medium induction additive to pre-treat NK cells, successfully enhancing the killing toxicity of NK cells against human lung cancer cells and effectively inhibiting tumor growth, opening up a new way for the treatment of lung cancer and having important research value and potential clinical application prospects in the field of tumor immunotherapy.

The invention belongs to the technical field of soil improvement, and relates to a soil saline-alkali improver as well as a preparation method and application thereof. The invention provides a soil saline-alkali modifier. The soil saline-alkali modifier is composed of a shell slow-release layer, a middle conditioning layer and an internal functional layer, the internal functional layer is prepared from a saline-alkali soil improving fungicide, biochar and a granulation adhesive; the middle conditioning layer is composed of a conditioner, a first slow-release agent and a first solvent; the shell slow-release layer is prepared from humic acid, furfural residues, a calcium ion compound, a second slow-release agent and a second solvent; the calcium ion compound is at least one of phosphogypsum, desulfurized gypsum, calcium chloride and calcium sulfate; the conditioner is at least one of coumarin, resveratrol and catechin. A multi-layer slow-release structure is constructed, through a multi-layer slow-release mode, all the improvement components make contact with the saline-alkali soil in sequence, and the excellent improvement effect is achieved.

The invention belongs to the technical field of pressure sore treatment, and discloses an experimental test method for treating stress injury based on danshen emodin, which comprises the following specific steps: step 1, preparing experimental materials, selecting a healthy SD (Sprague Dawley) rat, and preparing a clean and sterile magnet and a shaver; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1 part of isoflurane, 1 part of iodophor, 1 part of Vaseline, 1 part of Rhapontigenin and 1 part of resveratrol. The method comprises the following steps: modeling a stress injury model for an SD (Sprague Dawley) rat so as to simulate a stress injury disease, then respectively smearing three medicines, i.e., Danjie emodin, resveratrol and vaseline, tracking the healing condition of a stress injury wound, and finally performing ELISA (Enzyme-Linked Immunosorbent Assay) and Hamp; according to the present invention, the detection analysis is performed through the dyeing E, and the results show that the rheum emodin has good treatment effect on the stress injury, can reduce the expression of the proinflammatory factor, can promote the wound healing, has characteristics of environmental protection and low cost, and provides the new research direction for the treatment of the stress injury.

The invention discloses a method for preparing a double-nutrition fat substitute based on soybean protein-silibinin compound high internal phase emulsion, and belongs to the technical field of food processing. The method comprises the following steps: respectively preparing a soybean protein solution and a silybin solution to form a soybean protein-silybin compound, dissolving resveratrol into an oil phase by virtue of an ultrasonic dispersion means, and homogenizing at a high speed to prepare a soybean protein-silybin compound high internal phase emulsion as the double-nutrition fat substitute. The milk is green, healthy, low in cost and environment-friendly, and caters to the consumption requirements of vegetarians, people with specific diet requirements and people complying with religious diet restrictions, and the addition of the silibinin improves the antioxidant activity and stabilizes the emulsion interface, and endows the emulsion with antibacterial performance. Meanwhile, the resveratrol carried by the emulsion enables the fat substitute to have potential health benefits and nutritional value. The method for preparing the double-nutrition fat substitute which is similar to real fat in texture and healthy by packaging natural polyphenol through the soybean protein-silibinin high-internal-phase emulsion provides a wider development thought for application of the high-internal-phase emulsion; and the method is beneficial exploration of using the emulsion based on the vegetable protein as an effective substitute of saturated fat in various foods.

The invention discloses a yarrowia lipolytica engineering strain with high yield of resveratrol as well as construction and application of the yarrowia lipolytica engineering strain, and belongs to the technical field of synthetic biology and metabolic engineering. The invention provides a yarrowia lipolytica engineering strain. A 4-coumaric acid-CoA ligase gene, a multi-copy resveratrol synthase gene, a transketolase 1 gene, a fusion gene of a histidine phosphate aminotransferase gene and a tyrosine ammonia lyase gene, a glycolytic pathway hexokinase gene, a 6-phosphofructokinase-1 gene and a phosphoglycerate kinase gene are integrated, so that the recombinant protein is obtained. According to the present invention, by using glucose as the substrate, the high yield of resveratrol can be achieved by using glucose as the substrate, the resveratrol yield during shake-flask culture fermentation can achieve 3.157 g / L, the resveratrol yield can be increased to 30.7 g / L during 5L-scale fed-batch fermentation, and the resveratrol yield can be increased to 30.7 g / L when the resveratrol yield is increased to 30.7 g / L when the resveratrol yield is increased to 30.7 g / L when the resveratrol yield is increased to 30.7 g / L; the maximum value is reported by the yarrowia lipolytica system at present.

The invention relates to application of Bergapten or an isomer thereof in preparation of a product for improving skin aging and / or promoting skin repair. A large number of experiments prove that Bergapten or an isomer thereof can improve skin aging and / or promote skin repair and has good safety, and the specific expression is as follows: Bergapten can activate expression of SIRT1 protein and is superior to that of an existing activator resveratrol; the Bergapten can obviously inhibit the reduction of the content of various collagens in skin keratinocytes caused by UV light aging stimulation; the Bergapten can be used for promoting the healing capability of cell scratches. In conclusion, the Bergapten or the isomer thereof has great clinical application prospect and value in preparation of products for improving skin aging and / or promoting skin repair.

The present invention relates to the field of plant extraction, and in particular to an extraction process for skin care active ingredients in coffee peels. The present invention adopts a natural and pollution-free coffee peel extraction method, and extracts the natural active chemical components in the coffee peels through enzymatic biomimetic extraction, which can achieve the simultaneous extraction of chlorogenic acid, caffeic acid, and resveratrol in the coffee peels. The obtained extraction product has a high content of skin care active ingredients, which can be used as a cosmetic raw material to exert anti-inflammatory, anti-oxidation, whitening, soothing and other skin care effects; this technology makes full use of the production waste of coffee peels, reduces environmental pollution, recycles resources, and improves economic benefits.

A nutraceutical composition, consisting of Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

The invention provides a whitening emulsion based on oxyresveratrol-loaded exosome as well as a preparation method and application thereof, and belongs to the field of cosmetics. The oxyresveratrol-loaded exosome disclosed by the invention is prepared from the following components in parts by weight: 0.01 to 1 part of oxyresveratrol and 0.05 to 20 parts of exosome, wherein the oxyresveratrol is wrapped in the exosome; the weight ratio of the oxyresveratrol to the exosome is (1: 5)-(1: 20). When the oxyresveratrol-loaded exosome disclosed by the invention is prepared, when the weight ratio of the oxyresveratrol to the exosome is 1: (5-20), the loading capacity of the oxyresveratrol in the exosome can be greatly improved, so that the effects of the whitening and soothing composition and the whitening emulsion are ensured.

The invention discloses a plant cell activating factor as well as a preparation method and application thereof. The plant cell activating factor contains active ingredients such as resveratrol, quercetin, chlorogenic acid and the like. The active ingredients of the plant cell activating factor are obtained from natural plants, so that the plant cell activating factor has no pollution to the environment, is safe and harmless to human bodies and animals, and meets the requirements of green agricultural development. Experiments prove that the plant cell activating factor disclosed by the invention can effectively regulate the physiological activity of plant cells, activate the growth potential of plants, promote the development of plant root systems, thick and strong stalks and dark green leaves, and remarkably improve the growth speed and biomass accumulation of the plants, thereby increasing the yield of crops.

The invention belongs to the technical field of microorganisms, and relates to a plant lactobacillus NXU-F1 strain and application thereof. The classification name of the bacterial strain is lactobacillus plantarum, the bacterial strain is preserved in Guangdong Microbial Culture Collection Center on June 20, 2025, and the preservation number of the bacterial strain is GDMCC No.66563. The invention also discloses a preparation method of the bacterial strain. The plant lactobacillus is strong in growth capability, has good adaptive capacity to environment, and can obviously increase the content of antioxidant substances when being applied to plant matrix fermentation. The lycium barbarum and grape compound fermented beverage is prepared by fermenting the lycium barbarum and grape compound fermented beverage, the content of polyphenol, flavone, polysaccharide and procyanidine in the beverage is obviously increased, and the increase of resveratrol and ferulic acid is particularly obvious; meanwhile, ester compounds are increased and aldehyde substances are reduced, so that the beverage is endowed with strong longan fruity flavor, and the flavor of harmonious sour and sweet taste and lingering aftertaste is formed.

The invention provides a resveratrol preparation method, which comprises: mixing a compound 1 and an acylation reagent in an organic solvent, carrying out a reaction to obtain a compound 2, adding chlorobenzene and a catalyst, and carrying out a Friedel-Crafts reaction on the compound 2 and chlorobenzene under the ultraviolet light condition to obtain a compound 3, oxidizing the compound 3 to obtain 1-(4-phenol)-2-(3, 5-dihydroxyphenyl) ethanone; the preparation method comprises the following steps: reducing 1-(4-phenol)-2-(3, 5-dihydroxyphenyl) ethanone to obtain 1-(4-phenol)-2-(3, 5-dihydroxyphenyl) ethanol; and removing an alcoholic hydroxyl group in the 1-(4-phenol)-2-(3, 5-dihydroxyphenyl) ethanol to obtain the resveratrol.

The present invention provides an anti-aging, whitening, freckle-removing, moisturizing skin care water and a preparation process thereof. A preparation process for an anti-aging, whitening, freckle-removing, moisturizing skin care water comprises the following steps: supercritical CO2 extraction of oat-yarrow extract; ultrasonic-enzymatic hydrolysis-assisted reflux extraction and concentration; adding oxidized resveratrol, salidroside and ellagic acid; adding purified water to dissolve and adding sodium alginate and glycerol; adding p-anisic acid and aromatic alcohol and homogenizing and mixing. The present invention is a skin care water prepared by first extracting extracts of bletilla striata, wormwood leaf, peony bark, oat and yarrow, and then adding oxidized resveratrol, salidroside, ellagic acid, sodium alginate, glycerol, p-anisic acid and aromatic alcohol. The skin care water not only has the effects of anti-aging, whitening, freckle removal and moisturizing, but also because its raw materials are all natural plant ingredients and no chemical agents are added, therefore, it will not irritate the skin and has no side effects, and can be used for a long time.

The invention relates to the technical field of cosmetics and transdermal drug delivery, in particular to a resveratrol-tocoxolam nano-micelle and application of the resveratrol-tocoxolam nano-micelle in preparation of antioxidant and skin whitening products. The preparation method comprises the following steps: adding resveratrol or a derivative thereof into a first organic solvent (the weight percentage is 0.1-2%), and heating and dissolving at a first temperature of 80-100 DEG C to obtain a first solution; adding tocoxolam into the first solution, mixing (the weight percentage is 0.5-20%), and heating and dissolving at a second temperature (80-100 DEG C) to obtain a second solution; adding the second solution into the deionized water at a first rate (1mL / min to 3mL / min), and stirring and dispersing at a third temperature (50 DEG C to 70 DEG C); the nano-micelle is high in stability, excellent in transdermal absorption performance and good in anti-light aging effect, and has good skin whitening and anti-oxidation effects.

The invention belongs to the technical field of traditional Chinese medicines and cosmetics, and particularly relates to eutectic resveratrol, a liposome thereof, a preparation method and application of the eutectic resveratrol. The eutectic resveratrol is prepared from the following raw materials: resveratrol, amino acid and glycerol; the amino acid is selected from one of proline, lysine and arginine. The eutecticevaporate resveratrol liposome is prepared from the following raw materials: soybean phospholipid, cholesterol and eutecticevaporate resveratrol, the mass ratio of the soybean phospholipid to the cholesterol is (1-9): 1, and the mass ratio of the sum of the mass of the soybean phospholipid and the cholesterol to the mass of the eutecticevaporate resveratrol is 1: (0.5-2). A method capable of improving the solubility and stability of resveratrol is found, the eutectic resveratrol liposome which is stable in particle size and PDI and excellent in zeta potential and has certain anti-oxidation and antibacterial performance is prepared, the solubility, stability and bioavailability of resveratrol (RES) are improved, and the resveratrol liposome is suitable for being used as an anti-inflammatory drug. And a new thought is provided for further development and application research of resveratrol (RES).

The invention provides a resveratrol production strain and a construction method and application thereof, according to the strain, tyrAfbr, tyrB, aroE, pntAB, ompF, aroGfbr and accA genes are up-regulated, a carbon storage regulation factor csrA gene is knocked out, the transcriptional level of a fabF gene is down-regulated through a BBaJ23113 promoter, a TAL gene from Rhodotorula glutinis, a 4CL gene from Arabidopsis thaliana and an STS gene from Vitis vinifera are heterologously expressed on a genome, and the strain carries a high-copy plasmid PET-28a-WAL at the same time; the strain takes glucose as a carbon source, resveratrol is efficiently and stably synthesized from the beginning by adopting a fermentation method, the production cost is low, and efficient production of resveratrol is realized.

The invention discloses a drug-loaded polygonatum kingianum extracellular vesicle, a preparation method and an application of the drug-loaded polygonatum kingianum extracellular vesicle in preparation of an anti-photoaging product, and aims to provide a drug-loaded polygonatum kingianum extracellular vesicle which has relatively high encapsulation efficiency and drug loading rate and good stability and biocompatibility, can effectively treat skin UVB inflammation, solves the problem that a drug is insoluble in water, improves the curative effect, and can be used for preparing an anti-photoaging product and a preparation method of the drug-loaded polygonatum kingianum extracellular vesicle. According to the technical scheme, the drug-loaded polygonatum kingianum extracellular vesicles comprise the polygonatum kingianum extracellular vesicles and drug active components loaded in the polygonatum kingianum extracellular vesicles, and the drug-loaded polygonatum kingianum extracellular vesicles comprise the drug-loaded polygonatum kingianum extracellular vesicles and the drug active components loaded in the drug-loaded polygonatum kingianum extracellular vesicles. The pharmaceutical active component is at least one of resveratrol, glutathione, astaxanthin and vitamin C. The invention further discloses a preparation method of the pharmaceutical composition. The invention belongs to the technical field of biological medicine.

The invention provides a feed additive capable of improving immunity of pet cats as well as a preparation method and application of the feed additive, and belongs to the technical field of animal feed additives. The feed additive comprises probiotics and a traditional Chinese medicine extract, the probiotics comprise bifidobacterium animalis, combined lactobacillus salivarius and saccharomyces cerevisiae boulardii, and the traditional Chinese medicine extract comprises astragalus polysaccharide, curcumin and resveratrol. The probiotics directly enhance intestinal immunity through colonization resistance and metabolites, the traditional Chinese medicine components form internal and external dual defense through system immune activation, immunity-flora dual regulation is achieved, the probiotics and the traditional Chinese medicine extract form a symbiotic system of increasing the drug effect through bacteria and protecting the bacteria through drugs, and 1 + 1gt is achieved; and 2, the immunity improving effect is achieved.

The invention discloses an anti-aging composition, a preparation method and application of the anti-aging composition in skin aging resistance, belongs to the technical field of cosmetics, and aims at solving the problems that in related technologies, anti-aging cosmetics are instable in functional components, and the skin aging resistance of transdermal absorbability and functional component combination needs to be further improved. The anti-aging composition is prepared from the following components in percentage by total weight of the composition: 10 to 20 percent of an anti-aging functional composition and 80 to 90 percent of an auxiliary material matrix, the composition with the anti-aging effect is prepared from the following main components: ascorbyl tetraisopalmitate, epigallocatechin gallate, hydroxytyrosol, a calendula extract, curcumin, resveratrol and glutathione. The anti-aging composition prepared by the invention has good stability, transdermal absorbability and capability of improving skin aging resistance.

The invention discloses preparation and application of a whitening and repairing composition containing temperature-sensitive oxidized resveratrol hydrogel, and relates to the technical field of cosmetics. The composition comprises the following components in parts by weight: 1-5 parts of temperature-sensitive oxidized resveratrol hydrogel, 4-6 parts of a peucedanum praeruptorum dunn extract, 1-3 parts of a willowleaf swallowwort rhizome extract and 0.1-0.5 part of a tephrosia rubescens seed extract. The combination of the peucedanum praeruptorum dunn extract, the cynanchum wilfordii extract, the tephros glauca seed extract and the oxyresveratrol finds that the composition has a synergistic interaction effect, and the composition formed by the components through specific compatibility has the effects of whitening, repairing and improving skin elasticity. The oxidized resveratrol is wrapped by the temperature-sensitive hydrogel, so that the oxidized resveratrol is kept in a gel state at an epidermal cuticle layer, and after the oxidized resveratrol permeates into a skin basal layer, the oxidized resveratrol can be released at the skin basal layer, acts on melanocytes more effectively, inhibits tyrosinase and further affects generation of melanin.

The present invention relates to the technical field of anti-aging compositions and particularly to an anti-aging composition and use thereof, and an anti-aging capsule and use thereof. The present invention provides an anti-aging composition comprising the following components: 20-2000 parts by mass of calcium α-ketoglutarate, 20-100 parts by mass of quercetin, 20-2000 parts by mass of trans-resveratrol, 20-100 parts by mass of calendulin, and 0.02-1.8 parts by mass of spermidine. The composition of the present invention has a multi-target synergistic effect on 12 major causes of aging and can safely and effectively reverse aging, enhance the physiological function, reduce the risk of chronic diseases, and improve the quality of life. The components of the composition are safe, and are carefully selected natural food ingredients; therefore, the composition is safe and reliable, and has no side effects with long-term use. The composition is prepared in an oral dosage form, so that the composition is convenient to administer, which improves patient compliance; moreover, the mode of application of the composition can be expanded.