103 results about "Annona squamosa" patented technology

The invention discloses a sound surface wave resonator series detection and a detection method, the detection system comprises a resonance detector, a dc source and a digital counter, the digital counter is connected to a computer through a RS 232 communication interface, the resonance detector is arranged in a shielding box, the resonance detector has two probes, Annona squamosa L to be detected is placed between two probes; the detection system for detecting the storage life of Annona squamosa L comprises the following steps: step1, placing the Annona squamosa L to be measured between two probes; step 2, measuring Annona squamosa L to be measured, collecting the load frequency of the resonance detector by the digital counter; step 3, reading the load frequency data collected by the digital counter through the computer, and calculating storage time of the Annona squamosa L. The sound surface wave resonator series detection and the detection method can detect the storage time of Annona squamosa L in a rapid, simple and accurate mode, and the determination result is objective and reliable.

The invention discloses anti-aging sandwich noodles. The anti-aging sandwich noodles are made of, by weight, 100-200 parts of all-purpose flour, 10-20 parts of Annona Squamosa, 10-20 parts of Fructus Rosae, 4-8 parts of Undaria Pinnatifida, 3-6 parts of Lycium Ruthenicum, 15-30 parts of cucumber, 6-12 parts of corn kernels, 2-4 parts of black soybean, 1-2 parts of Poria Cocos, 1-2 parts of Endothelium Corneum Gigeriae Galli, 1-2 parts of edible salt, 3-6 parts of ultramicro ablumen powder, 5-10 parts of wheat gluten and a proper amount of fermented glutinous rice juice. Moisture inside finished noodles is low in fluidity and more uniform in distribution, and moisture migration speed and quality deterioration degree in the process of refrigerating are both lowered; various raw materials having anti-aging efficacy are processed into filling to be added into the centers of the noodles, so that the sandwich noodles made are uniform, orderly and full, free of scabbing and twisting, smooth in surface, crystal clear, free of breaking when being boiled for long time, muddying, adhesion and flour paste outflow, chewy in taste, elastic and smooth, free of stiffness feel, soft and palatable, and have a wide market prospect.

The present invention relates to a plant extract with the action of resisting diabetes, its application and preparation method. The extract is a kind of acetogenins extracted from branck, leaf, trunk, bark, root, seed and fruit skin of annona squamosa plant as raw material. The compound acetogenins can be made into various dosage forms for curing diabetes, and its preparation method can adopt oneor several processes of solvent extraction process, resin adsorption process, supercritical CO2 extraction process and conventional drying process.

The invention relates to a simple method for promoting AP sweetsop flower formation. The simple method for promoting the AP sweetsop flower formation specifically comprises the steps of performing selection, clipping, flower formation promotion, water management and fertilizer application management in a clipping and flower formation promotion period, wherein the clipping and flower formation promotion period ordinarily ranges from the last ten-day period of August of the current year to the first ten-day period of March of the next year; selecting and topping young sprouts grown in the current year, spraying plant growth regulator mixed liquor on topped branches without half of leaves and then performing the spaying for one time every three days, totally performing the spraying for 3-5 time so as to promote axillary bud growth, and providing guarantee for flower bud differentiation. In addition, when new axillary buds grow, 80mg / L-100mg / L auxin (IAA) can be spayed to serve as an auxiliary agent. In the clipping and flower formation promotion process, compound fertilizer, urea, lime and potassium chloride are ordinarily applied in five days before clipping. By utilizing the simple method, the flower formation rate of treated branches is obviously improved, an AP sweetsop flowering phase can be five days ahead of the phase by adopting a traditional flower formation promoting mode, the flower formation rate is improved by higher than 70%, and a basis is provided for efficient sweetsop cultivation.

The invention relates to a refined sweetsop total lactone for anticancer and a method for preparing the same. The method comprises that: Root, leaf and bark or seed of sweetsop are used as raw materials, are percolated and extracted by petroleum ether, chloroform, and acetic ether, or a mixed solution of the petroleum ether, the chloroform and acetic ether, or the raw materials are extracted by supercritical carbon dioxide; the raw materials adopts solvent method, namely the raw materials are heated and dissolved by the petroleum ether and are subjected to impurity removal to obtain sweetsop total lactone; and the sweetsop total lactone is subjected to silica gel column chromatography, is subjected to gradient elution by the petroleum ether-the acetic ether or the chloroform-methanol, and is separated and is refined to obtain the sweetsop total lactone taking Shikemoxin and valeric sweetsop as main compositions. The raw materials have rich sources, low price and availability; the obtained refined sweetsop total lactone has high content, clear compositions and controllable quality; and the preparation method has a simple process, low consumption and high yield, and can realize large industrialized production.

The invention relates to a preharvest and postharvest compound treatment method for AP annona squamosa refreshment and fruit cracking restraint. The preharvest and postharvest compound treatment method comprises the steps of enabling complexing agent solution composed of water, calcium chloride and jasmonic acid to be spayed on fruits 1-2 weeks before picking; selecting and harvesting the fruits which are uniform in sizes, have no pest and disease damage and have a maturity of 80-90%; first soaking the harvested fruits in pollution-free preservative solution I composed of water, citric acid, oxalic acid and ascorbic acid for 20-30min, taking out the fruits, and draining moisture; soaking the fruits in preservative solution II onion extracting solution; finally enabling the processed fruits to be aired naturally in an air-conditioning room at 18-20 DEG C, and storing the fruits in a cold storage which is at 15 DEG C and has a relative humidity of 75%-85%; and after storage for 15 days, enabling the fruit cracking rate and the rotting rate of AP annona squamosa to be reduced to be within 15%. According to the preharvest and postharvest compound treatment method, the fruit cracking rate can be effectively reduced, the storage period of the fruits is prolonged, and the flavor and quality of the AP annona squamosa are not affected.

The invention provides an annonaceous acetogenin extract extracted from seeds, leaves and barks of Annona squamosa L., a preparation method thereof, an external preparation taking the annonaceous acetogenin extract as an active ingredient, and medicinal use of the external preparation in cancer resistance and relief of cancerous pain. The preparation method for the annonaceous acetogenin extract has a simple process, common, low-price and low-toxicity reagents are adopted and are environment-friendly and relatively safe for human health, the production cost is lower, and the whole preparation method is easy to implement, can effectively shorten the production cycle and is suitable for mass production. An external patch comprising the annonaceous acetogenin extract serving as the active ingredient is easy to use, and has prominent curative effect on cancerous pain and no side effect.

The present invention provides an annona squamosa enzyme beverage preparation method. A fermentation raw material is prepared by using annona squamosa as main fermentation raw materials and adding raw honey and centenary excellent water (pure water) provided by Wuxi centenary excellent water beverage limited company at a volume ratio of the annona squamosal, raw honey and pure water of 2-4 : 1-4 : 7-2. Honey bacteria and lactic acid bacteria are used as fermentation strains and added in a proportion of 1-5%, respectively. The annona squamosa enzyme beverage is fermented at a fermentation temperature of 25-37 DEG C, a pH of 6.0-8.0, and a fermentation time of about 10 d. The annona squamosa enzyme beverage is fully fermented, various enzymes, vitamins, amino acids and trace elements are fully released, and thus the product has a unique flavor of the annona squamosa, is nutritious and tasty, uses the traditional fermentation technology, and belongs to the field of biotechnology engineering.

The invention discloses a traditional Chinese medicine composition capable of resisting novel coronavirus SARS-Cov-2 and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from folium isatidis, flos chrysanthemi indici, rhizoma coptidis, cherimoya seeds, agastache rugosus, rhizoma atractylodis, radix bupleuri, calculus bovis factitius, herba houttuyniae, dandelion root, honeysuckles, fructus forsythia, radix scutellariae, rhizoma belamcandae, salvia miltiorrhiza, bulbus fritillariae cirrhosae, saussurea involucrate, radix astragali, cordyceps militaris, radix codonopsis and liquorice. By carrying out screening in a large number of experiments according to pathogenic characteristics of the novel coronavirus SARS-Cov-2 and a viscera screening composition of concurrent injury, researches on in vitro safety and drug efficacy of in vitro novel coronavirus show that the traditional Chinese medicine composition disclosed by the invention has a remarkable inhibition effect to the novel coronavirus SARS-Cov-2. Clinical experimental observation shows that the traditional Chinese medicine composition is capable of remarkably improving pneumonia symptoms concurrent with the novel coronavirus SARS-Cov-2.

Provided are edible composite coating preservative for annona squamosa and a preparation method of the preservative. The preservative comprises a Chinese herbal medicine extracting solution and polysaccharide coating liquid which are used in two times; the Chinese herbal medicine extracting solution is prepared from, by mass, 2.5%-4% of coptidis rhizoma extracting solution, 1.5%-3% of folium artemisiae argyi extracting solution and the balance distilled water; the polysaccharide coating liquid is prepared from, by mass, 0.55%-0.85% of complex gum, 1%-2% of glycerin, 0.2%-0.45% of fruit green solution and the balance distilled water. The preservative can form a membrane on the surface of the annona squamosa, consumption of nutritional components such as organic acid and VC in fruits of the annona squamosa can be inhibited, the browning rate, the fruit cracking rate and the soluble solid conversion speed are decreased, ripening and softening process is delayed, the respiratory rate is inhibited, accumulation of malonaldehyde is reduced, the degree of cell membrane lipidic peroxidation is reduced, fruit senescence is delayed, and the good fresh-keeping effect is achieved.

Herbal compositions and their use in the prevention and / or treatment of hepatitis are provided The herbal compositions comprise an extract of flowers, leaves, and roots from the plant genera Cordia, Annona, and Curcuma, respectively, wherein the specific species are Cordia lutea, Annona muricata and Curcuma longa.

The invention discloses an annona squamosa picking device which comprises a gripping rod. The right side of the gripping rod is connected with a sawtooth pressure bar by a reset spring, the left sideof the gripping rod is connected with a trigger by a reset rotary shaft, a battery box is arranged inside the gripping rod and is connected with a guide block by a first wire, the lower end of the guide block is connected with the reset rotary shaft, the sawtooth pressure bar is connected with a steering gear train by a driving gear, the steering gear train is arranged at the lower end of a threaded rod, a connecting pipe is connected with the outer side of the threaded rod and is connected with a slide groove by a slider, the slide groove is formed in the inner side of a sleeve, and the sleeve is arranged at the upper end of the gripping rod. The annona squamosa picking device has the advantages that the annona squamosa picking device can bring convenience for picking annona squamosa at high locations, the simplicity of the annona squamosa picking device can be improved, and wires can be prevented from being twined in disorder; the probability of circuit failure of the annona squamosapicking device can be reduced, users or other people can be prevented from being accidentally injured by cutters, and the 2 cutters can be conveniently driven to cut branches connected with the annona squamosa.

The present invention discloses black sesame mixing nutrition medicinal granules and a preparation method thereof, wherein the raw materials comprise, by weight, 25-27 parts of black sesame, 20-22 parts of black beans, 15-17 parts of black fruit chinese wolfberry, 4-6 parts of lotus leaf, 2-4 parts of mulberry leaf, 9-11 parts of wax gourd seed, 10-12 parts of bitter gourd, 8-10 parts of carica papaya, 2-4 parts of green tea, 13-15 parts of coconut, 5-7 parts of annona squamosa, 8-12 parts of lucuma nervosa, 7-9 parts of kadsura coccinea, 4-6 parts of lonicera fragrantissima, 3-5 parts of chrysophyllum cainito, 2-4 parts of calcium fruit, 1-3 parts of coix seed powder, 1-3 parts of angelica dahurica powder, 1-3 parts of panax notoginseng powder, and 16-20 parts of brown sugar. The black sesame mixing nutrition medicinal granules of the present invention has characteristics of complete nutrition and good taste, and further has effects of blood fat lowering, blood pressure stabilizing, and blood nourishing.

The invention relates to the technical field of agricultural application, in particular to a pollination device and a method for increasing the hand pollination effect of annona squamosa by utilizingthe pollination device. According to the pollination device disclosed by the invention, the pollination efficiency is increased, the fruit setting rate is increased, and the generation of malformed fruits is reduced. According to the method disclosed by the invention, the pollination time is prolonged, and pollination can be favorably carried out by a large-scale orchard. The pollination device comprises a pipe sleeve, a pushing rod, a piston and a powder storage pipe, wherein a sliding cavity is formed in the pipe sleeve; a poking hole is formed in the side wall of the pipe sleeve; a pollination hole is formed in the front end of the powder storage pipe; the width of the pollination hole is 4 to 6 mm. The method adopts the pollination device one of any of claims 1 to 4 and comprises the following steps: (1) building spray irrigation facilities in an annona squamosa planting orchard, wherein the height of spray nozzles spaces from the annona squamosa by 40 to 50 cm, and water can be prevented from being sprayed to flowers; (2) starting to spray the water ahead of pollination by one hour when annona squamosa blooms, and enabling the humidity of the orchard to be up to 70 to 80 percent; (3) enabling the pollination time to be before 9 o'clock in the morning and after 17 o'clock in the afternoon.

The invention relates to a nano anti-saccharification composition as well as a preparation method and application thereof. The nano anti-saccharification composition is prepared from the following components: 5 parts of a nano cosolvent, 20 to 30 parts of plant extract, 10 to 15 parts of hydroxypropyl tetrahydropyranyl triol, 1.0 to 3.0 parts of fullerene, 1.0 to 2.0 parts of oligopeptide-1 and 2.0 to 5.0 parts of a polyol preservative, wherein the plant extract is prepared from lemon citriodora extract, citrus peel extract, rosa multiflora flower extract, sweet tea leaf extract, annona squamosa peel extract, folium eriobotryae extract, rosemary leaf extract and fructus hippophae extract. The nano anti-saccharification composition provided by the invention is more easily added into a commonly used preparation of cosmetics and more easily permeates into a skin cuticle to exert effects; a chemical synthetic preservative does not need to be added and the nano anti-saccharification composition is moderate and has no irritation; and the nano anti-saccharification composition can be used for remarkably improving dull skin color, improving the elasticity and compactness of skin and increasing the anti-saccharification capability of the skin.

The invention relates to sweetsop lactone extract and an extraction method thereof. The sweetsop lactone extract is an anticancer active ingredient obtained after extraction and separation of sweetsop seeds. The extraction method comprises the following steps: firstly, organic solvents such as ethanol, petroleum ether, chloroform, and so on are used for extracting sweetsop lactone from coarse powder of the sweetsop seeds; and secondly, the sweetsop lactone is subjected to silica gel column chromatography, chloroform-methanol elutioin, petroleum ether-ethyl acetate elution and ethyl acetate-metanol elution to obtain the sweetsop lactone extract of which the content is between 50 and 90 percent of mass percent. As proved by in vivo anticancer pharmacological experiments of animals, the sweetsop lactone extract has obvious functions in inhibiting the growth of lung cancer cells, breast cancer cells and liver cancer cells, and can be used for preparing an anticancer medicine because the anticancer activity of the sweetsop lactone extract is 100 percent higher than that of a chemotherapeutic medicine - 5-fluorouracil.

The invention discloses spleen-tonifying stomach-nourishing corn noodles and a preparation method thereof. The corn noodles comprise the following raw materials: corn flour, broad beans, snow pears, rice vinegar, grosvenor momordica flowers, collybia albuminosa, sea eel muddy flesh, annona squamosa, dried moss, cress, pea meal, gordon euryale meal, silene jenisseensis, pistachio nut fruits, black sesames, antler cap, platycodon grandiflorum, dracocephalum rupestre hance and the like. The noodles disclosed by the invention have the advantages that as a common coarse food grain, corn is good in taste and rich in nutrition and has the effects of tonifying spleen, nourishing stomach, draining dampness, delaying senescence and reducing blood sugar; and the noodles prepared from the corn as the main raw material are balanced in nutrition and have a very good health care efficacy.

The invention discloses a cutting planting method of custard apple. The cutting planting method comprises the following steps: (1) processing cuttings; (2) cutting; (3) nursing before transplanting; (4) transplanting seedlings; 5) watering and fertilizing; (6) harvesting. The custard apple planting method of the present invention promotes rapid rooting and germination of cutting seedlings, shortens the seedling cultivation period, and significantly improves the survival rate and yield of custard apples. The method is simple in operation, low in cost, and pollution-free, and is suitable for wide-scale popularization.

The invention relates to a fresh keeping agent for fresh cherimoya fruits and a use method of the fresh keeping agent. The fresh keeping agent comprises the following components in percentage by mass: 0.5-1.5% of citric acid, 4-8% of a fresh ginger extract, 5-12% of an argy wormwood leaf extract, 0.2-0.8% of garlic powder, 1-2% of hydroxylated chitosan and the balance of distilled water. The use method of the fresh keeping agent disclosed by the invention comprises the following steps of macerating the harvested fresh cherimoya fruits which are free from diseases and insect pests and are 80-90% in maturity in the fresh keeping agent for 20-30min, taking out the macerated fresh cherimoya fruits, draining the taken-out fresh cherimoya fruits, then putting the drained fresh cherimoya fruits in a freezer with the temperature being 10-15 DEG C and the relative humidity being 70-85%, and performing cold storage. According to the fresh keeping agent and the use method thereof disclosed by the invention, the technical problem of effectively keeping the fresh cherimoya fruits fresh is solved, the quality guarantee period of cherimoya is prolonged, and the industrialized development of the cherimoya sold to a distant place is promoted.

The present invention discloses a detox and disease-proof chicken feed, which is made from the following raw material by weight: 270-290 parts of corn, 10-12 parts of banana peel, 8-10 parts of glutinous rice flour, 6-8 parts of fresh fish, 8-10 parts of eggs, 4-5 parts of cynomorium, 6-8 parts of mulberries, 5-6 parts of heartleaf houttuynia herb, 3-5 parts of crystal sugar, 4-5 parts of rhubarb, 3-4 parts of divaricate saposhnikovia, 5-6 parts of rapeseed meal, 1-2 parts of calcium hydrogen phosphate, 2-3 parts of salt, 4-7 parts of walnut kernels, 6-8 parts of sweetsop leaves, 5-6 parts of accessory ingredient and a proper amount of water. According to the present invention, the detox and disease-proof chicken feed provides water, proteins, carbohydrates, fats, minerals, trace elements, vitamins and other feed energy according to the nutritional requirement of chickens, not only ensures the healthy growth of chickens, but also enhances the digestion, detoxification, immunity and disease resistance of chickens, meanwhile improves the quality and taste of chicken, and creates good economic benefits and ecological benefits. The added sweetsop leaves have hypoglycemic and anti-oxidation effects. The added berchemia kulingensis schneid has functions of dispelling wind and eliminating dampness, activating blood circulation and removing pain.

The invention discloses an o-bis-tetrahydrofuran type annonaceous acetogenins compound having antitumor activity. Through systemically deep researching on chemical ingredients of seeds of annona squamosa, wave spectrum and mass spectrum data analysis proves that the novel o-bis-tetrahydrofuran type annonaceous acetogenins compound can be separated from the seeds of annona squamosa. In-vivo and in-vitro antitumor activity researching proves that the o-bis-tetrahydrofuran type annonaceous acetogenins has strong antitumor activity on various tumor cells, such as lung cancer cells, breast cancer cells, liver cancer cells, etc., and also has significant inhibition activity on mouse transplanted liver tumor HepG2 and mouse sarcoma S180 solid tumor. Toxicity tests prove that the o-bis-tetrahydrofuran type annonaceous acetogenins compound has low toxicity and is an excellent antitumor compound.

The invention discloses a process for brewing annona squamosa health-protecting fruit wine. The process comprises the following steps: selecting fresh, ripe and plump annona squamosa as a main raw material; and performing raw material pretreatment, pulping, ultrafine micro-grinding, complex enzyme treatment, substrate pre-treatment, raw material mixing, alcohol fermentation, squeezing and filtering, brewing, canning, sterilizing and other steps. According to the process, fruit pulp is separated from fruit peels and fruit kernels, the fruit pulp is pulped, and the fruit peels and fruit kernels are subjected to ultrafine micro-grinding and are continuously utilized, so that the utilization of raw materials can be greatly improved, and the nutrition of the finished product annona squamosa wine can be enriched. The annona squamosa fruit wine has the health-protecting effects of reducing blood glucose, delaying senescence, promoting digestion and the like.

An anticancer annona lactone monomer 'itrabin' for preventing and treating liver cancer is prepared from the annona seeds through drying, breaking, immersing in petroether, recovering petroether to obtain red oily liquid, laying aside, filtering to obtain white deposit, chromatography, and eluting.

The invention relates to the fruit tree cultivation technical field, and specifically discloses an Annona squamosa L shoot promoting method comprising the following steps: selecting current year sprouted branches, topping the branches, and removing all or partial blades of the branch after topping; spraying calcium chloride solution with mass fraction of 3-5%; spraying cytokinin 1-2 hours later; repeating the said steps for 2-3 times in one week after branch topping and defoliation so as to promote axillalry bud germination, and forming new shoot. The method is very simple, can basically solve the problems that partial axillalry bud cannot germinate into new shoot in conventional artificial processing. The branches processed by the method can realize 85% axillalry bud germination rate 8days after branch topping and defoliation, and 78% of germination axillalry bud can grow new shoots 30 days after treatment.

The present invention discloses canned clove flavored annona squamosa fruits and a production method thereof. The canned clove flavored annona squamosa fruits are manufactured by using the cloves and annona squamosa fruits as raw materials and at the same time prepared from perilla frutescens and morinda umbellata. The production method fully utilizes the nutritional values of the cloves and annona squamosa fruits, the materials are combined with the traditional Chinese medicines, and the mixture has synergies, so that the canned clove flavored annona squamosa fruits have functions of supplementing kidneys and helping yang, and beautifying features and nourishing skin. The canned clove flavored annona squamosa fruits are subjected to a fruit wine distiller's yeast fermentation, which increases a mellow flavor of the products. The prepared finished products are rich in nutrition, mellow and sweet, have certain health-care functions, are easy to preserve, and can significantly alleviate the discomforts of populations with painful waists and legs caused by a long-term standing in a long-term consumption. The canned clove flavored annona squamosa fruits are simple in production processes, easy to achieve and in line with people's health needs, and can be subjected to a large-scale production.

The invention discloses beatifying and slimming coarse-cereal medicinal granules and a preparation method thereof. The beatifying and slimming coarse-cereal medicinal granules comprise the following raw materials which are proportioned in parts by weight: 45-47 parts of mung beans, 20-22 parts of black sesame seeds, 25-27 parts of oat, 8-10 parts of rose-flower powder, 4-6 parts of papaya powder, 5-7 parts of lotus-flower powder, 3-5 parts of purple sweet potato powder, 12-14 parts of pumpkins, 15-17 parts of broadleaf holly leave, 14-18 parts of ginseng-oolong, 8-10 parts of black Chinese wolfberry fruits, 5-7 parts of salak, 6-8 parts of solanum muricatum, 10-12 parts of annona squamosa, 2-4 parts of ficus pumila, 10-12 parts of pomegranate powder and 38-40 parts of brown sugar. The beatifying and slimming coarse-cereal medicinal granules are enriched in nutritional ingredients, and have good beatifying and slimming effects.

The invention provides a processing technology for preparing coconut milk by a whole coconut meat wet crushing method. The processing technology comprises the following steps that S1, fresh and maturecoconut meat is taken and soaked in a sodium chloride solution for 8-12 minutes, the coconut meat is washed with water, and crushed to obtain crushed coconut meat; S2, the crushed coconut meat, nonienzyme and coconut water are mixed, and low-temperature fermentation is carried out to obtain a coconut fermentation product; S3, the coconut fermentation product is added into a sodium carboxymethylcellulose aqueous solution for mixing, coarse grinding is carried out for 4-8 minutes in a wet-method superfine fine grinding machine under the conditions that the coarse grinding frequency is set tobe 20-40 Hz, the rotating speed is 3000-8000 rpm and a grinding disc is 0.3-0.6 mm, and fine grinding is carried out for 2-3 minutes under the conditions that the fine grinding frequency is set to be30-50 Hz, the rotating speed is 9000-12000 rpm and the grinding disc is 0.08-0.12 mm to obtain ground pulp; and S4, the ground pulp is mixed with an annona squamosa extract, a clinacanthus nutans extract and trehalose, uniform stirring is carried out, and after homogenizing is carried out twice, sterilization and vacuum concentration are carried out to obtain the coconut milk. The coconut milk prepared by the processing technology is good in overall stability and has relatively high oxidation resistance and antibacterial property.

The invention provides application of compound of any one or more of a formula I, a formula II and a formula III for the preparation of a medicament for treating brain malignant gliomas or melanoma and belongs to the technical field of tumor medicines. The compound shown in the formula I, the formula II and the formula III is a monomer ingredient in an annona squamosa total lactones extract. The invention further provides a method for preparing an annona squamosa seed extract for treating human brain malignant gliomas or melanoma and a product thereof. The compound shown in the formula I, theformula II and the formula III and the extract (including effective parts) have an efficient killing effect on the brain malignant gliomas or melanoma. Particularly, the compound shown in the formulaI has an IC 50 value of only 0.4044 nM for brain malignant gliomas U87-MG, and an IC50 value of only 0.5152 nM for melanoma SK-MEL-28, while the IC50 for most other tumors is often between 1uM and 100uM, and the difference is more than three orders of magnitude, showing a selective and efficient killing effect on brain malignant gliomas U87-MG and melanoma SK-MEL-28.