Composition with multi-dimensional soothing and repairing effects and application thereof

Abstract

The invention relates to the technical field of cosmetics, in particular to a composition with multi-dimensional soothing and repairing effects and application of the composition. The lactobacillus / soybean milk fermentation product filtrate, the hydrolyzed sericin, the Chinese herbaceous peony root extract and the willow leaf extract are combined for use, and the effect of reducing skin redness can be quickly achieved, so that the prepared composition finished product has excellent skin soothing and repairing effects; in addition, free radicals are removed in real time through the waxberry fruit extract, ultraviolet oxidative stress is dealt with in a targeted mode through the annona squamosa fruit extract, and the overall anti-oxidation defense capacity is enhanced through the sargassum micranthum extract. The three components are combined to achieve a complementary effect, and the anti-oxidation effect of the prepared composition finished product can be remarkably improved. According to the invention, the soothing, repairing and anti-oxidation effects are taken as a whole, so that the relieved and repaired skin can be effectively prevented from being damaged again, the durability of the repairing effect can be prolonged, and the health state of the skin is more stable.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, specifically to a composition with multi-dimensional soothing and repairing effects and its application. Background Technology

[0002] With the increasing complexity and diversity of external stimuli in modern life, skin sensitivity has become a common health concern for many. Currently, most skin-soothing and repairing products on the market focus on a single pathological aspect, such as quickly relieving irritation through a single neuromodulatory ingredient, repairing the physical barrier with exogenous lipid supplements, or inhibiting specific inflammatory pathways using anti-inflammatory active ingredients. While these methods can temporarily relieve symptoms, they generally neglect the harmful effects of oxidation in the skin sensitivity process. Existing commercially available products often treat soothing and repair separately from anti-oxidation, resulting in repaired skin still being exposed to a high oxidative stress environment, making the repair effect unsustainable and leading to recurring sensitivity problems. Many products contain soothing ingredients that only act on the surface, lacking intervention on the root cause of oxidative stress. Such single-function products cannot fundamentally break the vicious cycle of skin sensitivity.

[0003] Therefore, in view of the problems existing in the existing technology, it is necessary to provide a system that can deeply integrate soothing repair and anti-oxidation and synergistic effect, thereby targeting multiple key links to establish a soothing repair defense mechanism and achieve true multi-dimensional soothing repair. Summary of the Invention

[0004] In view of the problems existing in the existing cosmetic composition technology, the purpose of this invention is to provide a composition with multi-dimensional soothing and repairing effects and its application.

[0005] The objective of this invention can be achieved through the following technical solutions: The first aspect of this invention provides a composition with multi-dimensional soothing and repairing effects, comprising the following raw materials: Microbial fermentation filtrate, plant extracts, sericin, humectants, emulsifiers, preservatives, solvents.

[0006] In some embodiments, the microbial fermentation filtrate includes at least one of yeast / rice fermentation product filtrate, lactobacillus fermentation lysate, lactobacillus / soybean milk fermentation product filtrate, and lactobacillus / rice fermentation product.

[0007] Furthermore, the microbial fermentation filtrate is preferably a lactobacillus / soy milk fermentation product filtrate.

[0008] In some embodiments, the microbial fermentation filtrate comprises 3.6-5.5 parts by weight of lactobacillus / soybean milk fermentation product filtrate.

[0009] In some embodiments, the plant extracts include at least one of the following: peony root extract, kava leaf / root / stem extract, willowherb leaf extract, calendula extract, immortelle extract, Sargassum fusiforme extract, knotweed root extract, custard apple fruit extract, centella asiatica extract, and waxberry fruit extract.

[0010] Furthermore, the plant extracts are preferably peony root extract, willowherb leaf extract, Sargassum fusiforme extract, custard apple fruit extract, and waxberry fruit extract.

[0011] In some embodiments, the plant extracts include 3-5.5 parts by weight of peony root extract, 1-2.8 parts by weight of willowherb leaf extract, 1.5-3 parts by weight of Sargassum fusiforme extract, 0.4-0.6 parts by weight of custard apple fruit extract, and 2.2-4.6 parts by weight of waxberry fruit extract.

[0012] In some embodiments, the sericin includes silkworm sericin or hydrolyzed sericin.

[0013] Furthermore, the sericin is preferably hydrolyzed sericin.

[0014] In some embodiments, the sericin comprises 2.5-4 parts by weight of hydrolyzed sericin.

[0015] In some embodiments, the humectant includes at least one of glycerin, propylene glycol, 1,4-butanediol, panthenol, betaine, glyceryl glucoside, and calendula seed oil.

[0016] Furthermore, the humectant is preferably butylene glycol and panthenol.

[0017] In some embodiments, the humectant comprises 10-18 parts by weight of 1,4-butanediol and 15-25 parts by weight of panthenol.

[0018] In some embodiments, the emulsifier includes cetearyl oleate or PEG-100 glyceryl stearate.

[0019] In some embodiments, the emulsifier is 4-6 parts by weight.

[0020] In some embodiments, the preservative includes phenoxyethanol or sodium benzoate.

[0021] Furthermore, the preservative is preferably phenoxyethanol.

[0022] In some embodiments, the preservative is 0.3-0.5 parts by weight.

[0023] In some embodiments, the solvent includes deionized water.

[0024] In some embodiments, the solvent is 39-45 parts by weight.

[0025] A second aspect of the present invention provides a method for preparing a composition with multi-dimensional soothing and repairing effects, comprising the following steps: Step 1: Mix and stir the solvent and humectant to obtain mixture A; Step 2: Heat and stir the emulsifier until all the emulsifier is completely melted to obtain mixture B; Step 3: Add mixture B to mixture A while controlling the temperature and speed. After adding, stir and cool to obtain mixture C. Step 4: Add the microbial fermentation filtrate, sericin, and plant extract to mixture C in sequence at a controlled speed and stir. Add the preservative, stir again, and then homogenize at a controlled speed to obtain the final product of the composition.

[0026] In some embodiments, the stirring time in step 1 is 10-15 minutes.

[0027] In some embodiments, the heating in step 2 is water-cooled heating to 60-65°C.

[0028] In some embodiments, the temperature and speed control in step 3 are 60-65°C and 3000-3500 rpm; the stirring time is 3-5 min; and the cooling is to cool to 35-40°C.

[0029] In some embodiments, the speed control in step 4 is 1500-2000 rpm; the stirring time is 30-45 min; the stirring time after re-stirring and homogenization is 5-10 min, the speed is 3000-3500 rpm, and the homogenization time is 3-5 min.

[0030] The third aspect of this invention provides the application of a composition with multi-dimensional soothing and repairing effects in the preparation of cosmetics.

[0031] In some embodiments, the composition with multidimensional soothing and repairing effects is added in an amount of 3-5% of the total mass of the cosmetic.

[0032] In some embodiments, the cosmetics include, but are not limited to, toners, serums, lotions, and creams.

[0033] The beneficial effects of this invention are: (1) The formation of skin sensitivity mainly involves multiple mechanisms, including dysfunction of the skin sensory nerve system, inflammatory response, damage to the skin barrier and infection of the skin epidermis by microbial flora. In most cases, these mechanisms do not work alone, but lead to skin sensitivity in a complex form of interaction. Therefore, this invention correspondingly selects Lactobacillus / soy milk fermentation product filtrate to exert a nerve-soothing effect, selects hydrolyzed sericin to reduce inflammatory response, selects peony root extract to enhance skin barrier function, and selects willowherb leaf extract to exert antibacterial effect, thereby targeting the nerve-inflammation-skin barrier-antibacterial mechanism to soothe and repair the skin from the root.

[0034] (2) The present invention uses waxy myrica fruit extract to immediately scavenge free radicals; uses hairy custard fruit extract to specifically address ultraviolet oxidative stress; and uses microalgae extract to enhance the overall antioxidant defense capability. Therefore, the combination of the three has a synergistic effect and can significantly improve the antioxidant efficacy of the prepared composition. Compared with the use of a single component, the composition of the present invention can resist oxidative damage more comprehensively and stably.

[0035] (3) Soothing and repair can only address existing skin damage and cannot actively combat free radicals. The skin may fall into a cycle of repair-damage-re-repair. Therefore, the composition product prepared by this invention adds antioxidant ingredients to the soothing and repair process to further resist oxidative damage. The combination of the two can effectively prevent the soothed and repaired skin from being damaged again, and can prolong the duration of the repair effect, making the skin healthier and more stable. Detailed Implementation

[0036] The technical solution of the present invention is illustrated below through specific examples. It should be understood that the one or more method steps mentioned in the present invention do not preclude the existence of other method steps before or after the combined steps, or the insertion of other method steps between these explicitly mentioned steps; it should also be understood that these embodiments are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, unless otherwise stated, the numbering of each method step is merely a convenient tool for identifying each method step, and not for limiting the order of the method steps or defining the scope of the present invention. Changes or adjustments to their relative relationships, without substantially altering the technical content, are also considered to fall within the scope of the present invention.

[0037] To better understand the above technical solutions, exemplary embodiments of the present invention are described in more detail below. While exemplary embodiments of the present invention are shown, it should be understood that the present invention can be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to enable a more thorough understanding of the present invention and to fully convey the scope of the invention to those skilled in the art.

[0038] The composition with multi-dimensional soothing and repairing effects provided by this invention comprises the following raw materials: Microbial fermentation filtrate, plant extracts, sericin, humectants, emulsifiers, preservatives, solvents.

[0039] Soothing and repairing products can only address existing skin damage and cannot actively combat free radicals. As a result, the skin may fall into a cycle of repair-damage-re-repair. Therefore, the composition of this invention adds antioxidants to the soothing and repairing products to further resist oxidative damage. The combination of these two ingredients can effectively prevent the soothed and repaired skin from being damaged again, and can also prolong the duration of the repair effect, making the skin healthier and more stable.

[0040] In one embodiment, the microbial fermentation filtrate includes at least one of yeast / rice fermentation product filtrate, lactobacillus fermentation lysate, lactobacillus / soybean milk fermentation product filtrate, and lactobacillus / rice fermentation product.

[0041] Specifically, the microbial fermentation filtrate is preferably a lactobacillus / soy milk fermentation product filtrate; Lactobacillus / soy milk fermentation product filtrate is obtained through multi-strain biomimetic co-culture fermentation. It has the effect of regulating the skin microecological environment and improving the diversity of skin microorganisms. In addition, it can inhibit TRPV1 activity, reduce the excessive response of nerve endings to external stimuli and help reduce neurogenic inflammation. At the same time, it can also inhibit the activation of pain and itch-related sensory receptors TRPV1 / TRPA1 by reducing calcium ion influx, thereby effectively inhibiting the transmission of itch and pain signals and achieving a nerve-soothing effect.

[0042] In one embodiment, the microbial fermentation filtrate comprises 3.6-5.5 parts by weight of lactobacillus / soy milk fermentation product filtrate.

[0043] In one embodiment, the plant extract includes at least one of the following: peony root extract, kava leaf / root / stem extract, willowherb leaf extract, calendula extract, immortelle extract, Sargassum fusiforme extract, knotweed root extract, custard apple fruit extract, centella asiatica extract, and waxberry fruit extract.

[0044] Specifically, the plant extract is preferably: Peony root extract, rich in active ingredients such as paeoniflorin, tannic acid, and polysaccharides, can increase the moisture content of the stratum corneum of the skin and enhance the skin barrier function by upregulating the expression of transcription factor EGR3. Willowherb leaf extract, whose main active ingredients are tannins, flavonoids, polyphenols and gallic acid derivatives, can disrupt the integrity of bacterial cell membranes and inhibit bacterial nucleic acid and protein synthesis, thus exerting antibacterial effects. Sargassum extract significantly enhances the expression of catalase, superoxide dismutase and glutathione peroxidase by activating the Keap1 / Nrf2 / ARE signaling pathway, thereby reducing lipid peroxidation, accelerating free radical decomposition, and enhancing overall antioxidant defense capabilities. The fruit extract of Anolum sarmentosum is rich in bioactive components such as polyphenols, flavonoids, and tannins. It can alleviate oxidative stress caused by ultraviolet radiation by increasing the activity of antioxidant enzymes and reducing MDA levels. The extract of waxy myrica fruit can neutralize various free radicals such as peroxide free radicals, superoxide anions and hydroxyl free radicals and interrupt the chain reaction of free radicals to exert an antioxidant effect.

[0045] In one embodiment, the plant extract includes 3-5.5 parts by weight of peony root extract, 1-2.8 parts by weight of willowherb leaf extract, 1.5-3 parts by weight of Sargassum fusiforme extract, 0.4-0.6 parts by weight of custard apple fruit extract, and 2.2-4.6 parts by weight of waxberry fruit extract.

[0046] In one embodiment, the sericin includes silkworm sericin or hydrolyzed sericin.

[0047] Specifically, the sericin is preferably hydrolyzed sericin, which can effectively inhibit the expression and activity of COX-2, a key factor that causes inflammation, and reduce the production of PGE2. At the same time, it can also inhibit pro-inflammatory factors such as IL-6, IL-18, and IL-33, reduce inflammatory response, and achieve multidimensional redness reduction, thus reconstructing a good skin foundation.

[0048] In one embodiment, the sericin comprises 2.5-4 parts by weight of hydrolyzed sericin.

[0049] In one embodiment, the humectant includes at least one of glycerin, propylene glycol, 1,4-butanediol, panthenol, betaine, glyceryl glucoside, and calendula seed oil.

[0050] Specifically, the humectant is preferably butylene glycol and panthenol.

[0051] In one embodiment, the humectant comprises 10-18 parts by weight of 1,4-butanediol and 15-25 parts by weight of panthenol.

[0052] In one embodiment, the emulsifier comprises cetearyl oleate or PEG-100 glyceryl stearate.

[0053] In one embodiment, the emulsifier is 4-6 parts by weight.

[0054] In one embodiment, the preservative includes phenoxyethanol or sodium benzoate.

[0055] Specifically, the preservative is preferably phenoxyethanol.

[0056] In one embodiment, the preservative is 0.3-0.5 parts by weight.

[0057] In one embodiment, the solvent includes deionized water.

[0058] In one embodiment, the solvent is 39-45 parts by weight.

[0059] This invention also provides a method for preparing a composition with multi-dimensional soothing and repairing effects, comprising the following steps: Step 1: Mix and stir the solvent and humectant to obtain mixture A; Step 2: Heat and stir the emulsifier until all the emulsifier is completely melted to obtain mixture B; Step 3: Add mixture B to mixture A while controlling the temperature and speed. After adding, stir and cool to obtain mixture C. Step 4: Add the microbial fermentation filtrate, sericin, and plant extract to mixture C in sequence at a controlled speed and stir. Add the preservative, stir again, and then homogenize at a controlled speed to obtain the final product of the composition.

[0060] In one embodiment, the stirring time in step 1 is 10-15 minutes.

[0061] In one embodiment, the heating in step 2 is water-cooled heating to 60-65°C.

[0062] In one embodiment, the temperature and speed control in step 3 are 60-65℃ and 3000-3500 rpm; the stirring time is 3-5 min; and the cooling is to cool to 35-40℃.

[0063] In one embodiment, the speed control in step 4 is 1500-2000 rpm; the stirring time is 30-45 min; the stirring time for homogenization after re-stirring is 5-10 min, the speed is 3000-3500 rpm, and the homogenization time is 3-5 min.

[0064] The present invention also provides the application of a composition with multi-dimensional soothing and repairing effects in the preparation of cosmetics.

[0065] In one embodiment, the amount of the composition with multi-dimensional soothing and repairing effects added is 3-5% of the total mass of the cosmetic.

[0066] In one embodiment, the cosmetics include, but are not limited to, toners, serums, lotions, and creams.

[0067] The present invention will be further described below with reference to the following embodiments.

[0068] The lactobacillus / soy milk fermentation product filtrate used in this invention was purchased from Xianting (Guangzhou) Trading Co., Ltd. The hydrolyzed sericin used was purchased from SkinSource (Shanghai) Biotechnology Research Co., Ltd. The peony root extract used was purchased from Shanghai Zhengxin Biotechnology Co., Ltd. The willowherb leaf extract used was purchased from Xi'an Jiatian Biotechnology Co., Ltd. The waxy bayberry fruit extract used was purchased from Nantong Zhonghe Chemical New Materials Co., Ltd. The extract from the fruit of the hairy soursop was purchased from Guangzhou Daixun Trading Co., Ltd. The Sargassum fusiforme extract used was purchased from Gansu Yishengxiang Biotechnology Co., Ltd. The above will not be repeated hereafter. Example 1

[0069] A composition with multi-dimensional soothing and repairing effects, comprising the following ingredients: Microbial fermentation filtrate: 4.6 parts by weight of lactobacillus / soy milk fermentation product filtrate; Plant extracts: 3 parts by weight of peony root extract, 1.9 parts by weight of willowherb leaf extract, 2.2 parts by weight of Sargassum fusiforme extract, 0.6 parts by weight of custard apple fruit extract, and 3.4 parts by weight of waxberry fruit extract. Sericin: 4 parts by weight of hydrolyzed sericin; Moisturizers: 10 parts by weight of 1,4-butanediol, 20 parts by weight of panthenol; Emulsifier: 5 parts by weight of cetearyl oleate; Preservative: 0.3 parts by weight of phenoxyethanol Solvent: 45 parts by weight of deionized water; The preparation method of the above-mentioned composition with multi-dimensional soothing and repairing effects includes the following steps: Step 1: Mix the solvent and humectant and stir for 10 minutes to obtain mixture A; Step 2: Heat the emulsifier in a water bath to 65°C and stir until all the emulsifier is completely melted to obtain mixture B; Step 3: Add mixture B to mixture A at a controlled temperature of 62.5℃ and a controlled speed of 3500 rpm. After adding, stir for 3 minutes and then cool to 35℃ to obtain mixture C. Step 4: Add the microbial fermentation filtrate, sericin, and plant extract to mixture C at a speed of 1750 rpm and stir for 30 min. Then add the preservative and stir for another 7.5 min. Homogenize at a speed of 3000 rpm for 4 min to obtain the final product. Example 2

[0070] A composition with multi-dimensional soothing and repairing effects, comprising the following ingredients: Microbial fermentation filtrate: 5.5 parts by weight of lactobacillus / soy milk fermentation product filtrate; Plant extracts: 4.3 parts by weight of peony root extract, 1 part by weight of willowherb leaf extract, 3 parts by weight of Sargassum fusiforme extract, 0.4 parts by weight of custard apple fruit extract, and 4.6 parts by weight of waxberry fruit extract. Sericin: 2.5 parts by weight of hydrolyzed sericin; Moisturizers: 18 parts by weight of 1,4-butanediol, 15 parts by weight of panthenol; Emulsifier: 4 parts by weight of PEG-100 glyceryl stearate; Preservative: 0.4 parts by weight of phenoxyethanol Solvent: 41.3 parts by weight of deionized water; The preparation method of the above-mentioned composition with multi-dimensional soothing and repairing effects includes the following steps: Step 1: Mix the solvent and humectant and stir for 10 minutes to obtain mixture A; Step 2: Heat the emulsifier in a water bath to 65°C and stir until all the emulsifier is completely melted to obtain mixture B; Step 3: Add mixture B to mixture A at a controlled temperature of 62.5℃ and a controlled speed of 3500rpm. After adding, stir for 3 minutes and then cool to 35℃ to obtain mixture C. Step 4: Add the microbial fermentation filtrate, sericin, and plant extract to mixture C at a speed of 1750 rpm and stir for 30 min. Then add the preservative and stir for another 7.5 min. Homogenize at a speed of 3000 rpm for 4 min to obtain the final product. Example 3

[0071] A composition with multi-dimensional soothing and repairing effects, comprising the following ingredients: Microbial fermentation filtrate: 5.5 parts by weight of lactobacillus / soy milk fermentation product filtrate; Plant extracts: 4.3 parts by weight of peony root extract, 1 part by weight of willowherb leaf extract, 3 parts by weight of Sargassum fusiforme extract, 0.4 parts by weight of custard apple fruit extract, and 4.6 parts by weight of waxberry fruit extract. Sericin: 2.5 parts by weight of hydrolyzed sericin; Moisturizers: 18 parts by weight of 1,4-butanediol, 15 parts by weight of panthenol; Emulsifiers: 3 parts by weight of cetearyl oleate and 3 parts by weight of PEG-100 glyceryl stearate; Preservative: 0.5 parts by weight of phenoxyethanol Solvent: 39.2 parts by weight of deionized water; The preparation method of the above-mentioned composition with multi-dimensional soothing and repairing effects includes the following steps: Step 1: Mix the solvent and humectant and stir for 15 minutes to obtain mixture A; Step 2: Heat the emulsifier in a water bath to 62.5°C and stir until all the emulsifier is completely melted to obtain mixture B; Step 3: Add mixture B to mixture A at a controlled temperature of 65℃ and a controlled speed of 3000rpm. After adding, stir for 5 minutes and then cool to 40℃ to obtain mixture C. Step 4: Add the microbial fermentation filtrate, sericin, and plant extract to mixture C at a speed of 2000 rpm and stir for 42.5 min. Then add the preservative and stir for another 10 min. Homogenize at a speed of 3250 rpm for 5 min to obtain the final product.

[0072] Comparative Example 1 The difference from Example 1 is that no lactobacillus / soy milk fermentation product filtrate was added, and the missing weight was supplemented with hydrolyzed sericin, peony root extract and willowherb leaf extract in a mass ratio of 4:3:1.9, while other aspects remained unchanged.

[0073] Comparative Example 2 The difference from Example 1 is that hydrolyzed sericin is not added, and the missing weight is made up by using lactobacillus / soy milk fermentation product filtrate, peony root extract, and willowherb leaf extract in a mass ratio of 4.6:3:1.9, while other aspects remain unchanged.

[0074] Comparative Example 3 The difference from Example 1 is that peony root extract was not added, and the missing weight was made up with lactobacillus / soy milk fermentation product filtrate, hydrolyzed sericin, and willowherb leaf extract in a mass ratio of 4.6:4:1.9, while other aspects remained unchanged.

[0075] Comparative Example 4 The difference from Example 1 is that willowherb leaf extract was not added, and the missing weight was made up with lactobacillus / soy milk fermentation product filtrate, hydrolyzed sericin, and peony root extract in a mass ratio of 4.6:4:3, while other aspects remained unchanged.

[0076] Comparative Example 5 The difference from Example 1 is that waxberry fruit extract is not added, and the missing weight is made up with custard apple fruit extract and Sargassum fusiforme extract in a mass ratio of 0.6:2.2, while other aspects remain unchanged.

[0077] Comparative Example 6 The difference from Example 1 is that the extract of *Annona squamosa* fruit is not added, and the missing weight is made up with extracts of *Myrica rubra* fruit and *Sargassum fusiforme* fruit in a mass ratio of 3.4:2.2, while other aspects remain unchanged.

[0078] Comparative Example 7 The difference from Example 1 is that Sargassum fusiforme extract is not added, and the missing weight is made up with Annona squamosa fruit extract and Myrica rubra fruit extract in a mass ratio of 0.6:3.4, while other aspects remain unchanged.

[0079] Test Example 1 Volunteers were recruited according to the inclusion and exclusion criteria of the "Diagnostic Criteria and Treatment Principles for Cosmetic Contact Dermatitis". Both men and women were included, and volunteers were divided into 8 groups: 7 experimental groups and 1 control group, with 10 volunteers in each group. A 2cm x 2cm square area on the inner side of the left forearm was selected as the test area. The test area was cleaned with water and the volunteers sat still for 10 minutes. The skin redness value was measured using a German CK multifunctional skin tester. The test area was then stimulated with 0.01mL of 50% capsaicin aqueous solution for 15 minutes before data collection. For the experimental groups, 0.05mL of the composition prepared in Examples 1-3 and Comparative Examples 1-4 was applied to the test area of ​​each volunteer (each composition accounted for 5% of the total mass of the test sample, with the remainder being the same test sample matrix). Data was collected after 30 minutes. For the control group, 0.05mL of pure water was applied, and data was collected after 30 minutes. The average values ​​measured in the test areas of each group of volunteers were statistically analyzed, and the redness fading rate was calculated using the following formula to analyze the changes in redness values: Redness reduction rate (%) = (Redness value after 15 min capsaicin treatment - Redness value after 30 min water treatment) / Skin redness blank value × 100%; The results are shown in Table 1.

[0080]

[0081] As shown in Table 1, the redness reduction rate of Examples 1-3 of the present invention is higher than that of the comparative example and the blank group. This is because the present invention combines Lactobacillus / soy milk fermentation product filtrate, hydrolyzed sericin, peony root extract and willowherb leaf extract, which can quickly reduce skin redness. Therefore, the finished product of the composition obtained thereby has excellent soothing and repairing effects on the skin.

[0082] Test Example 2 (1) Sample solution preparation: Deionized water was added to the compositions obtained in Examples 1-3 and Comparative Examples 5-7 respectively to prepare sample solutions with a mass concentration of 3%; (2) Test method: Take 4 mL of 0.1 mmol / L DPPH-anhydrous ethanol solution and add 2 mL of sample solution. Mix well and keep at room temperature in the dark for 30 min. Measure the absorbance at 517 nm and record it as A1. Take 4 mL of anhydrous ethanol solution and 2 mL of sample solution and measure the absorbance under the same conditions as above and record it as A2. Take 4 mL of 0.1 mmol / L DPPH-anhydrous ethanol solution and 2 mL of anhydrous ethanol solution and measure the absorbance under the same conditions as above and record it as A3. Calculate the DPPH free radical scavenging rate using the following formula: DPPH radical scavenging rate (%) = [1 - (A1 - A2) / A3] × 100%; The test was conducted three times, and the average value of the results was taken. The results for each group are shown in Table 2.

[0083]

[0084] As shown in Table 2, the DPPH free radical scavenging rate of the raw materials in Examples 1-3 of this invention is higher than that of Comparative Examples 5-7. This is because the present invention uses waxberry fruit extract to immediately scavenge free radicals, uses custard apple fruit extract to specifically address ultraviolet oxidative stress, and uses Sargassum fusiforme extract to enhance the overall antioxidant defense capability. The combination of the three has a synergistic effect and can significantly improve the antioxidant efficacy of the prepared composition.

[0085] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the invention. The illustrative expressions of the above terms in this specification should not be construed as necessarily referring to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. In addition, those skilled in the art can combine and integrate the different embodiments or examples described in this specification.

[0086] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A composition with multi-dimensional soothing and repairing effects, characterized in that, Including the following raw materials: Microbial fermentation filtrate, plant extracts, sericin, humectants, emulsifiers, preservatives, solvents.

2. The composition with multi-dimensional soothing and repairing effects according to claim 1, characterized in that, The microbial fermentation filtrate includes at least one of yeast / rice fermentation product filtrate, lactobacillus fermentation lysate, lactobacillus / soy milk fermentation product filtrate, and lactobacillus / rice fermentation product.

3. The composition with multi-dimensional soothing and repairing effects according to claim 2, characterized in that, The microbial fermentation filtrate includes 3.6-5.5 parts by weight of lactobacillus / soy milk fermentation product filtrate.

4. The composition with multi-dimensional soothing and repairing effects according to claim 1, characterized in that, The plant extracts include at least one of the following: peony root extract, kava leaf / root / stem extract, willowherb leaf extract, calendula extract, immortelle extract, Sargassum fusiforme extract, knotweed root extract, custard apple fruit extract, centella asiatica extract, and waxberry fruit extract.

5. The composition with multi-dimensional soothing and repairing effects according to claim 4, characterized in that, The plant extracts include 3-5.5 parts by weight of peony root extract, 1-2.8 parts by weight of willowherb leaf extract, 1.5-3 parts by weight of Sargassum fusiforme extract, 0.4-0.6 parts by weight of custard apple fruit extract, and 2.2-4.6 parts by weight of waxberry fruit extract.

6. The composition with multi-dimensional soothing and repairing effects according to claim 1, characterized in that, The sericin includes silkworm sericin or hydrolyzed sericin.

7. The composition with multi-dimensional soothing and repairing effects according to claim 6, characterized in that, The sericin comprises 2.5-4 parts by weight of hydrolyzed sericin.

8. The composition with multi-dimensional soothing and repairing effects according to claim 1, characterized in that, The humectant comprises 10-18 parts by weight of 1,4-butanediol and 15-25 parts by weight of panthenol; the emulsifier comprises cetearyl oleate or PEG-100 glyceryl stearate, wherein the emulsifier comprises 4-6 parts by weight; the preservative comprises 0.3-0.5 parts by weight of phenoxyethanol; and the solvent comprises 39-45 parts by weight of deionized water.

9. A method for preparing a composition with multi-dimensional soothing and repairing effects as described in any one of claims 1-8, characterized in that, Includes the following steps: Step 1: Mix and stir the solvent and humectant to obtain mixture A; Step 2: Heat and stir the emulsifier until all the emulsifier is completely melted to obtain mixture B; Step 3: Add mixture B to mixture A while controlling the temperature and speed. After adding, stir and cool to obtain mixture C. Step 4: Add the microbial fermentation filtrate, sericin, and plant extract to mixture C in sequence at a controlled speed and stir. Add the preservative, stir again, and then homogenize at a controlled speed to obtain the final product of the composition.

10. The use of a composition with multi-dimensional soothing and repairing effects as described in any one of claims 1-8 in the preparation of cosmetics, wherein the amount of the composition with multi-dimensional soothing and repairing effects added is 3-5% of the total mass of the cosmetic.

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