282 results about "SILK SERICIN" patented technology

The invention discloses a double-layer microneedle patch and a preparation method thereof.The preparation method of the double-layer microneedle patch comprises the following steps that firstly, 3D printing is conducted through polydimethylsiloxane, and a PDMS mold similar to a machining microneedle is obtained; dispersing the medicine into the sericin solution to serve as an outer layer solution; dispersing germanium nanoparticles into the polycaprolactone solution to obtain an inner layer solution; and finally, adding the outer-layer solution into the needle-shaped groove of the PDMS mold, so that the needle-shaped groove is filled with the outer-layer solution, drying, adding the inner-layer solution, drying, and demolding to obtain the double-layer microneedle patch. When the double-layer microneedle patch is used for drug delivery, drugs can be dissolved and released in a short time, the inner layer is polycaprolactone (PCL) carrying photo-thermal agent germanium nanoparticles, degradation is slow, a photo-thermal effect is generated under irradiation of 808nm near-infrared light, residual tumor cells are induced to die immunogenicity, an immune microenvironment is programmed in a time sequence, and the double-layer microneedle patch has the advantages of being high in sensitivity, high in sensitivity and good in stability. Postoperative recurrence and metastasis of tumors are efficiently inhibited, and meanwhile operative wound repair is promoted.

The invention relates to a mussel-like polylipoic acid-based hydrogel adhesive as well as a preparation method and application thereof, and the preparation method comprises the following steps: (1) uniformly mixing a sericin solution and a caffeic acid solution, then carrying out grafting reaction to obtain a reaction solution, and carrying out dialysis treatment and drying on the reaction solution to obtain sericin grafted caffeic acid; (2) adding lipoic acid into the lithium hydroxide solution, stirring until the lipoic acid is completely dissolved, then adding sericin grafted caffeic acid, and heating for reaction to obtain a PTALi-CAS mixture; and (3) cooling the PTALi-CAS mixture, so as to obtain the mussel-like polylipoic acid-based hydrogel adhesive. The dual-network PTALi-CAS hydrogel adhesive obtained in the invention realizes wet adhesion and rapid hemostasis, has excellent comprehensive performance, and is beneficial to providing a good repair environment for wounds as a wound dressing.

The invention provides a nanoparticle compound for inhibiting bone and soft tissue infection as well as a preparation method and application thereof, and belongs to the technical field of medical biological materials. The nanoparticle compound is a gentiopicroside, sericin, hyaluronic acid and endolysin liposome nanoparticle, and a gentiopicroside, sericin, hyaluronic acid and endolysin co-delivery nano drug delivery system targeting the S100A4 site is designed based on the target S100A4 closely related to bone infection through Ai molecular docking and nano drug delivery technologies. The nanoparticle compound provided by the invention has better stability and bioavailability, and can be used for improving and relieving inflammatory response and increasing wound healing effect.

The invention provides an anti-pilling wool fabric and a treatment method thereof, and belongs to the technical field of wool fabric processing. According to the treatment method for improving the anti-pilling performance of the wool fabric, the wool fabric with the anti-pilling performance is obtained, and the problems that in the prior art, in order to prevent pilling of the wool fabric, protease is used for treating the wool fabric, the efficiency is too low, and industrialization cannot be achieved are solved. Through the synergistic effect of the bacterial cellulose and the sericin, the anti-pilling performance of the wool fabric is improved, and the method is easy and convenient to operate, high in efficiency and suitable for industrial production.

The invention discloses a preparation method of visible-light-cured fibroin / sericin protein hydrogel, silk fibers containing different amounts of sericin are obtained by adjusting the concentration of a degumming reagent and the degumming time, the silk fibers are directly dissolved to prepare a fibroin / sericin protein composite aqueous solution by a one-step method, extra extraction of sericin or addition of sericin protein powder is not needed, and the preparation method is simple and convenient. The cost is reduced while the preparation process is greatly shortened; environment-friendly and nontoxic riboflavin (vitamin B2) is used as a photoinitiator, and crosslinking can be initiated under visible light without using ultraviolet light; the visible light curing fibroin / sericin hydrogel makes full use of respective performance advantages of silk fibroin and sericin in silk fibers, is safe in components, free of additional chemical cross-linking agents, good in light transmission, good in biocompatibility, high in elasticity, especially suitable for the field of biomedical materials, short in preparation process, short in time consumption and high in efficiency.

The present invention relates to a composition capable of improving the sunscreen performance of a sunscreen, and a preparation method and application thereof. The preparation method of the composition capable of improving the sunscreen performance of a sunscreen comprises the following steps: mixing and dissolving a metal ion salt and silk fibroin in water to obtain a silk fibroin metal ion complex solution; mixing the silk fibroin metal ion complex solution with hydroxyapatite to obtain a hydroxyapatite silk fibroin metal ion mixed solution; mixing the hydroxyapatite silk fibroin metal ion mixed solution with sericin to obtain the composition capable of improving the sunscreen performance of a sunscreen. The composition has excellent ultraviolet absorption performance, can be compatible with chemical sunscreens, improve the sunscreen performance of the sunscreen, and can avoid direct contact between the chemical sunscreen and the skin, thereby reducing the sensitization and skin irritation of the chemical sunscreen.

The invention relates to the technical field of plastic bags, in particular to an antibacterial degradable plastic bag and a preparation method thereof. The antibacterial degradable plastic bag is prepared from the following raw materials in parts by weight: 60-80 parts of polyhydroxyalkanoate, 30-40 parts of filler, 2-4 parts of an antioxidant and 0.6-1 part of an active agent. In the preparation process of the antibacterial degradable plastic bag, in a filler system, vesuvianite powder and eggshell powder are used as inorganic reinforcing phases, sericin and mulberry leaf powder are used as bioactive phases, flax and cotton provide a natural fiber structure, and lignin and konjac glucomannan are used as bio-based bonding materials; and the eggshell powder is compact in crystal structure after being subjected to high-temperature calcination treatment, and can be used as a stress transfer medium in a material system, so that the stress concentration when the plastic bag is stressed is reduced, and the strength performance of the plastic bag is improved.

The invention relates to the technical field of biological material preparation, and particularly discloses a method and a system for industrial continuous production of silk fibroin. In order to solve the problems of high energy consumption, heavy pollution, low efficiency, poor product stability and the like in the prior art, efficient removal of sericin is realized through a gradient degumming synergistic treatment technology (high-temperature and high-pressure alkali treatment and directional enzymolysis), and desalination and concentration are synchronously completed in combination with a membrane separation directional purification technology (a hollow fiber ultrafiltration system). The system integrates the gradient degumming module, the dissolution-filtration coupling module, the membrane separation module and the resource circulation subsystem, the technological parameters (degumming rate, viscosity and transmembrane pressure difference) are regulated and controlled in real time through the intelligent control center, the continuous production stability is ensured, the purity of the obtained silk fibroin solution is larger than or equal to 99%, and the standard of beauty makeup materials is met. The method and the system for industrial continuous production of silk fibroin have the advantages of high efficiency, low consumption and environmental protection, and are suitable for large-scale production.

The invention discloses a preparation method and application of an environment-friendly easily-degradable hydrogel coating, and relates to the technical field of hydrogel coatings. The coating is a coating comprising chitosan, acrylic acid, sericin, silk fibroin, silk peptide, tea polyphenol, a photoinitiator, a plasticizer and a leveling agent. The preparation method comprises the following steps: (1) preparing the coating containing the components; (2) coating the surface of food packaging paper with the coating liquid in a slit coating manner; and (3) performing ultraviolet light initiation to obtain the coating. The hydrogel coating has a synergistic effect with the sericin, the silk fibroin, the silk peptide and the tea polyphenol to form a compact and uniform network structure, so that the water-retaining property, the mechanical strength, the flexibility and the antibacterial property are enhanced; the preservative not only has the advantages of environmental protection and degradability, but also has the functions of moisturizing, antibiosis and preservation, and can significantly prolong the shelf life of food and improve the quality. The environment-friendly packaging paper is applied to food packaging paper, not only conforms to the green packaging trend, but also expands the use scenes of environment-friendly materials in the fields of fresh food, baking and the like.

The invention relates to antistatic dust-free cloth and a preparation method thereof, and belongs to the technical field of dust-free cloth. A plasma treatment technology is adopted to remove impurities on the surface of polyester fibers and increase the contact area of the polyester fibers, and sericin is added for modification, so that the compatibility and binding force of the polyester fibers and conductive fibers are effectively improved, and meanwhile, the finished cloth is endowed with softer touch feeling; polyethylene glycol glycidyl ether is introduced and can be combined with sericin to form a cross-linked structure, so that the antistatic performance is further improved, and the softness and wear resistance are optimized. Active groups can be introduced to the surfaces of the carbon fibers through mixed acid treatment, and the compatibility of the carbon fibers and the modified polyester fibers is enhanced. Polyoxyethylene alkylamine permeates into the fibers by using a decompression infiltration technology, and the dust-free cloth has a long-acting antistatic effect by combining the antistatic property of the conductive fibers. The comprehensive performance of the cloth is effectively improved, the requirement of the electronic industry for the high anti-static performance of the dust-free cloth is met, and wide application prospects are achieved.

The present application relates to the field of textile technology, and specifically discloses a high-elastic hygroscopic antistatic composite fiber and a preparation method thereof; a high-elastic hygroscopic antistatic composite fiber, comprising the following raw materials in parts by weight: 20-40 parts of polytrimethylene terephthalate, 60-80 parts of polyethylene terephthalate, 10-18 parts of nano inorganic particles, 5-8 parts of sericin, 5-10 parts of sulfonic acid hydrophilic modifier, 3-5 parts of polyether ester antistatic agent, 5-8 parts of carbon nanotubes, and 1-3 parts of surfactant; the polyether ester antistatic agent is preliminarily prepared into an antistatic masterbatch with carbon nanotubes; by combining polytrimethylene terephthalate and polyethylene terephthalate, under the synergistic effect of other components, the elasticity, antistatic and hygroscopic properties of the composite fiber can be improved on the basis of maintaining the original strength of the fiber.

The invention discloses a preparation method of a silk fibroin-polydopamine water-based binder, the silk fibroin-polydopamine water-based binder and application of the silk fibroin-polydopamine water-based binder. The preparation method comprises the following steps: (1) removing sericin from silkworm cocoons by using a sodium carbonate solution, drying, and dissolving degummed silk by using a lithium bromide solution; (2) dialyzing the solution dissolved in the step (2), and freeze-drying I to obtain water-soluble silk fibroin; (3) dissolving the obtained water-soluble silk fibroin in water to obtain a silk fibroin solution; and (4) adding dopamine hydrochloride into the silk fibroin solution for reaction, and performing freeze drying II to obtain the silk fibroin-polydopamine water-based binder. The binder prepared by the invention can effectively improve the ionic conductivity of a positive electrode and the transmission efficiency of sodium ions, and effectively improve the cycle performance and rate capability of a battery.

The invention relates to the technical field of textile fabrics, in particular to a moisture-absorption breathable polyester and chinlon composite fiber and a preparation method thereof. The invention relates to a moisture-absorbing breathable polyester and chinlon composite fiber, which is a skin-core composite fiber, takes moisture-conducting polyester fiber as a skin layer, and takes water-absorbing modified chinlon fiber as a core layer, the moisture-conducting polyester fibers are prepared from the following components in parts by weight: 68 to 75 parts of superfine denier polyester filaments, 12 to 16 parts of seaweed extract powder, 4 to 6 parts of lyocell fibers and 5 to 11 parts of a moisture-conducting auxiliary agent; the moisture conducting auxiliary agent comprises cellulose nano fibrils, nano bamboo charcoal powder and sericin. Aiming at the problem that the moisture absorption and air permeability of the existing polyester-nylon composite fiber are difficult to meet higher industrialization requirements, the moisture absorption and air permeability type polyester-nylon composite fiber with high water absorption rate, short drip diffusion time and water evaporation speed is prepared.

The invention discloses a sericin low-hysteresis composite conductive hydrogel as well as a preparation method and application thereof, the hydrogel takes a copolymer of methacrylamide phenylboronic acid and acrylamide as a matrix, and the composite conductive hydrogel is formed by introducing polydopamine modified sericin and aluminum ions. In the hydrogel, a boric acid group on a main chain reacts with a phenolic hydroxyl group into which sericin is introduced, so that the hydrogel has excellent self-repairing capability, and a secondary structure of the sericin is changed from disorder to alpha-helix and beta-folding in the reaction, so that the hydrogel has excellent low hysteresis capability; the introduction of aluminum ions provides good conductivity for the hydrogel. A sensor prepared from the hydrogel can respond to the deformation of human body movement and monitor the resistance change during joint movement, so that the real-time monitoring of the movement state is realized. The preparation process is simple and convenient, the materials are green and environment-friendly, and the method has wide application prospects and is suitable for the fields of design of wearable sensors, sports motion correction and the like.

The invention relates to the technical field of mulberry silk fabric processing, and discloses a mulberry silk fabric precise temperature control degumming system and a method thereof.The method includes the following steps that firstly, silk fabric surface temperature data are collected through distributed temperature sensors, and a temperature distribution thermodynamic diagram is generated and output to a central controller; the method comprises the following steps of 1, obtaining a temperature distribution thermodynamic diagram, 2, constructing a three-dimensional temperature field prediction model based on the temperature distribution thermodynamic diagram obtained in the step 1, and calculating colloid dissolution activation energy difference values of all areas, and 3, dynamically dividing gradient temperature control areas according to the activation energy difference values obtained in the step 2, and generating target temperature curves and time parameters of all the areas. According to the invention, through cooperative regulation and control of the multi-channel execution mechanism, the problem of non-uniform temperature distribution in a traditional process is effectively eliminated, and the heating uniformity of the fabric surface is remarkably improved, so that selective removal of sericin is realized, and high consistency of degumming degree is ensured while fiber damage is avoided; the strict requirements of high-end silk products on the material integrity are met.

The invention discloses preparation and application of bacteriophage-loaded sericin microgel, and belongs to the technical field of food preservation. The sericin microgel capable of loading the bacteriophage is prepared from a sericin solution extracted by using 1-ethyl-(3-dimethylaminopropyl) carbodiimide (EDC) in combination with a mechanical shearing method and a high-temperature and high-pressure method. The sericin protein microgel loaded with bacteriophage, which is obtained by soaking the microgel into bacteriophage proliferation liquid after freeze-drying, can significantly improve the storage stability of the bacteriophage and can effectively prolong the shelf life of beef, and the preparation method is green, simple and safe, has a wide application prospect, and is suitable for industrial production. Meanwhile, a new field is opened up for efficient application of the bacteriophage.

The invention discloses preparation of a sericin modification-based perovskite thin film and application of the sericin modification-based perovskite thin film in a perovskite solar cell, and belongs to the field of perovskite solar cells. The sericin is used as an additive to regulate and control the perovskite precursor solution, so that on one hand, the problems of rough surface and many defects of a perovskite layer caused by stress concentration in the growth process of perovskite crystal grains are solved, and on the other hand, the sericin plays a role in deprotonation; and the photoelectric conversion efficiency and the stability of the perovskite solar cell can be obviously improved.

The invention provides a wool fabric anti-pilling finishing agent and a preparation method, and relates to the field of fabric finishing agents, the wool fabric anti-pilling finishing agent comprises a dry material and a wet material, the dry material is obtained by adding a seaweed extract and oleuropein into a mixture of sericin and water and performing microwave treatment, low-temperature drying treatment and crushing treatment on the mixture, and the wet material is obtained by adding the seaweed extract and the oleuropein into the mixture. The wet material is obtained by mixing tea polyphenol, oleanolic acid and water. The anti-pilling finishing agent for the wool fabric, provided by the invention, is prepared from the sericin, the seaweed extract, the oleuropein, the tea polyphenol and the oleanolic acid materials, and the application of the natural materials not only is environment-friendly, but also can enhance the mechanical properties of the wool fabric while improving the anti-pilling property and the antistatic property of the wool fabric; after the anti-pilling finishing agent for the wool fabric is applied to the wool fabric, the wool fabric has the anti-pilling property and the durability.

The invention provides a method for separating sericin from silk degumming wastewater, which comprises the following steps: adding a cross-linking reagent into the silk degumming wastewater, uniformly mixing to obtain a mixed system, adding acid into the mixed system to adjust the pH value of the mixed system to 1.5-4.5, and keeping the mixed system at 30-80 DEG C for 10-90 minutes; adding a bridging reagent into the mixed system, uniformly mixing, standing to obtain a precipitate, and separating the precipitate to obtain the sericin, so that the problems that the sericin in the silk degumming wastewater of enterprises is difficult to recover, the cost is high, the COD value of the wastewater is high, secondary pollution is easily generated in the recovery process and the like at present are solved.

The invention relates to the technical field of food preservation, in particular to a double-layer fiber membrane for food preservation and a preparation method and application of the double-layer fiber membrane. The first layer of the double-layer fiber membrane for food preservation is composed of sericin / pullulan, and the second layer is a polylactic acid-based membrane doped with FA-coated Ag-ZIF-8 nanoparticles. The double-layer fiber membrane realizes high selectivity to oxygen and carbon dioxide, realizes regulation and control of microenvironment gas atmosphere, and inhibits respiration, so that an excellent fresh-keeping effect is achieved. The double-layer fiber membrane has antibacterial and antioxidant functions, and can inhibit oxidative degradation and microbial contamination of perishable fruits. According to the technology, dual mechanisms of gas regulation and control and biological protection are integrated, an innovative scheme is provided for solving the rotting problem of perishable fruits, and the technology shows important potential in the aspects of promoting development of a food fresh-keeping technology and optimizing a sustainable packaging scheme.

The invention belongs to the technical field of antibacterial materials, and particularly relates to a sericin / tannic acid-silver antibacterial-anti-biofilm nanocomposite as well as a preparation method and application thereof. According to the method, the TA-Ag nano material is prepared by adopting a simple water bath method; and then, dispersing SS in a TA-Ag aqueous solution to realize hydrogen bond combination of SS and TA so as to obtain the SS / TA-Ag nanocomposite with a stable structure. In the preparation process, plant polyphenol tannic acid is taken as a carrier, silver ions and tannic acid are combined by adopting a water bath method, and the antibacterial property of tannic acid is effectively improved; and the sericin is further modified through hydrogen bond crosslinking, so that the obtained composite material not only has antibacterial and anti-biofilm dual functions, but also is simple in preparation process and mild in reaction condition, and conforms to green chemistry and environment-friendly concepts.

The invention belongs to the field of biomedical materials, and particularly relates to a coagulation-promoting embolism microsphere and a preparation method thereof. The sericin-based embolism microspheres are creatively prepared, and the sericin membrane layer on the surface of the microspheres can prevent the risk that a catheter is solidified during an operation due to thrombin burst release during the operation. On the other hand, sericin in the microspheres has excellent water absorption swelling property and lubricity, and is beneficial to embolism and prevention of reflux; moreover, sericin molecules contain a large amount of hydroxyl and carboxyl, so that the chelation of blood coagulation factor calcium ions is greatly improved. In addition, thrombin factors are loaded into the microspheres, calcium ions are chelated on the surfaces of the microspheres, the microspheres are endowed with rapid embolism capacity through the superimposed effect, blood flow blocking of target blood vessels can be effectively accelerated, and reflux is prevented. The prepared procoagulant embolism microspheres are suitable for being applied to treatment of vascular-rich tumors of the brain and can effectively prevent mistaken closure of many complex functional blood vessels of the brain due to reflux.

The invention relates to the technical field of plant cultivation, and particularly discloses a method for improving drought tolerance of plants, sericin protein liquid and application, and the method comprises the following steps: preparing the sericin protein liquid with the concentration of 0.1-0.5 g / L, and then spraying the sericin protein liquid on leaf surfaces of tomato plants. According to the method for improving the drought tolerance of the tomato plants, the survival rate, the biomass and the water content of the tomato plants in the drought stress environment are remarkably improved.

This invention provides an antimicrobial peptide spray, its preparation method, and its application in the prevention and treatment of peristomal skin infections. The spray comprises, by weight percentage, 0.05%-0.5% of a complex antimicrobial peptide, 0.1%-5% of a moisturizing and repairing film-forming matrix, 0.05%-0.2% of a buffer, 0.8%-1.2% of an isotonic regulator, 0.01%-0.5% of a stabilizer, and 0.005%-0.05% of a metal ion chelating agent, with the balance being water for injection. The complex antimicrobial peptide is composed of bovine lactoferrin antimicrobial peptide, sericin oligopeptide, and buckwheat-derived anti-inflammatory active peptide in a weight ratio of (3-5):(2-3):1. This spray possesses four core functions: broad-spectrum antibacterial activity, inhibition of bacterial biofilm, anti-inflammatory and soothing effects, and skin barrier repair. It is less likely to induce bacterial resistance, does not irritate damaged skin around the stoma, and can effectively prevent and treat peristomal skin infections.

The invention discloses a scalp repair composition as well as a preparation method and application thereof. The scalp repair composition comprises sericin, ceramide NP, a purslane extract, polysorbate-20 and a water-phase matrix, the sericin and the ceramide NP are compounded to simulate a natural scalp cuticle structure, and barrier reconstruction is facilitated; the purslane extract is used for relieving pruritus and erythema in the repairing process; the pH value of the composition is 5.0-5.8, so that the composition is more suitable for the weakly acidic microenvironment of the scalp, and the irritation is effectively reduced. The composition can be applied to scalp repair essence, anti-hair loss products and medical auxiliary dressings, and has good safety and repair efficacy.

The invention relates to the field of cell cryopreservation, and provides a cryopreservation method for improving the survival rate of mesenchymal stem cells in order to solve the problem that the survival rate of the cells is obviously reduced after the usage amount of a cryoprotectant is reduced in the prior art, the cryopreservation method for improving the survival rate of the mesenchymal stem cells comprises the following steps: S100, resuspending the mesenchymal stem cells through a cryopreservation solution to obtain a cell suspension; the cryopreservation liquid comprises a permeable cryoprotectant and silk short fibers; sericin is reserved on the outer surface of the silk short fiber raw material; s200, performing freezing operation on the cell suspension to realize cell preservation; in the freezing operation process, the sericin protein is partially or completely separated out. After the silk short fibers with sericin are added into the cell suspension, the fibers can be used for protecting cells and providing attachment sites of the cells, a silk fibroin structure can also be used for promoting separation of solute, the solute is directly sericin, the osmotic pressure difference inside and outside the cells in the freezing process can be reduced through separation of the solute, and the freezing speed of the cells is increased. The survival rate of the cells is improved.

The present application relates to the technical field of neutral ink, and particularly relates to a sericin micro-nanoparticle neutral ink, a preparation method and application thereof, sericin micro-nanoparticles 0.05% to 20%, colorant 0.05% to 40%, additive 0.05% to 1.0%, antibacterial agent 0.05% to 1.0%, and the balance is water; the sericin micro-nanoparticles are prepared from sericin through glutamine transaminase crosslinking. The present application adopts glutamine transaminase crosslinking sericin protein to form sericin micro-nanoparticles as a film forming agent and a load stable base material, which is added into neutral ink, has a higher specific surface area, more hydrophobic groups and hydrophilic groups, so as to load and disperse biodegradable natural colorant through interface interaction, so that the neutral ink is functionalized, has higher colorant loadability, and meanwhile, the sericin micro-nanoparticles have excellent antioxidant property, can effectively protect biodegradable colorant, and improve the photo-thermal stability thereof.

The invention relates to a soft capsule, in particular to a long-acting DHA soft capsule and a preparation method thereof. The long-acting DHA soft capsule is prepared from the following raw materials in parts by weight: 10 to 11 parts of xanthan gum, 3 to 4 parts of locust bean gum, 0.5 to 1 part of sericin, 0.5 part of glycerol and 13.5 to 16 parts of deionized water. The preparation method comprises the following steps: stirring and heating to 75-80 DEG C until all the raw materials are dissolved in water or melted and solid particles visible to naked eyes do not exist, so that the raw materials are glue liquid; spreading the glue solution into a rubber sheet; pressing the capsule skin and the DHA grease composition into capsules through a soft capsule pelleting machine; after shaping, polishing and drying to obtain the long-acting DHA soft capsule. The capsule skin of the long-acting DHA soft capsule is of a single-layer structure, the structure is simple, the physicochemical property is determined, a traditional soft capsule pelleting machine can be used for pressing, an additional secondary coating process is not needed, and the production process is simplified; through cooperation of xanthan gum and locust bean gum, the gum skin keeps certain dimensional stability in a freezing environment.

The invention relates to the field of biomedical polymers, in particular to an antibacterial, compression-resistant and degradable pure sericin nano-composite gel dressing as well as a preparation method and application thereof. Main raw materials comprise sericin, magnesium lithium silicate, an initiator, a catalyst, an antibacterial agent and deionized water. The preparation method comprises the following steps: extraction of sericin, preparation of an inorganic nano-clay magnesium lithium silicate dispersion liquid, preparation of a gel pre-polymerization liquid, assembly of a sandwich model, injection of a sericin / magnesium lithium silicate gel pre-polymerization liquid, and preparation of the sericin / magnesium lithium silicate nano-composite gel. And carrying out post-treatment and packaging on the sericin / magnesium lithium silicate nano-composite gel dressing. The pure sericin protein hydrogel is prepared through interaction of hydrogen bonds and ionic bonds, the raw materials are non-toxic, and the pure sericin protein hydrogel has biocompatibility, high mechanical property, injectability, dissolvability and no pollution of dissolved products and can be used for wound dressing, drug delivery, biological binders, implantable electronic equipment and 3D biological printing.

The invention relates to the technical field of biological medicines, in particular to application of canthaxanthin extract and a feed additive containing the canthaxanthin extract in silkworm breeding, and finds that cocoon shell amount, whole cocoon amount and pupa weight of silkworms can be remarkably increased and egg laying amount of single moths can be increased by adding canthaxanthin extract to silkworms for the first time. Meanwhile, the silkworm variety with functional carotenoid binding protein can also be induced to produce orange red natural colored cocoons. The invention further provides a compound feed additive containing the canthaxanthin extract and the sericin-derived small peptide and / or gamma-aminobutyric acid. Experiments prove that the canthaxanthin extract and the sericin-derived small peptide have a synergistic effect in the aspect of increasing the cocoon shell amount. According to the technical scheme, on the premise that normal growth and development of silkworms are not affected, the multiple purposes of yield increasing, propagation promoting and color increasing are achieved at the same time, and the method has good application prospects and industrial value.