6results about How to "Ingredient safety" patented technology

The present application relates to a kind of salvianolic acid C freeze-dried preparation and preparation method and application, the salvianolic acid C freeze-dried preparation includes salvianolic acid C, pH adjusting agent, stabilizer and excipient.The salvianolic acid C freeze-dried preparation provided in the present application is traditional Chinese medicine extract, and each additive is suitable for administration route, component is safe, and good stability can be achieved, suitable for long-term storage, process is simple, reproducibility is good, easy to large-scale industrial production.The salvianolic acid C freeze-dried preparation of the present application can be injected to administration, also can be atomized to give human respiratory tract, provide a kind of new treatment means for anti respiratory tract influenza virus such as influenza virus A H1N1, influenza virus A H3N2, influenza virus B, parainfluenza virus, respiratory syncytial virus, adenovirus, etc., and have good curative effect.

The invention provides a water-based fire extinguishing agent and a preparation method thereof, and belongs to the technical field of fire extinguishing agents. The water-based fire extinguishing agent comprises a component A and a component B, the component A comprises potassium bicarbonate, potassium carbonate, potassium chloride and sodium acetate, and the component B comprises glycerin and water; the water-based fire extinguishing agent disclosed by the invention is clean in components, safe and pollution-free, can exert a remarkable fire extinguishing effect on general fire disasters, oil fire disasters, edible oil fire disasters and other fire disasters occurring in a home environment, and has very good practicability.

The invention provides a fresh-keeping solution for fresh-cut fruits and vegetables as well as a preparation method and application of the fresh-keeping solution. The fresh-keeping liquid comprises the following components in parts by weight: 0.06-1 part of limonene, 0.3-1 part of an emulsifier, 0.5-1 part of egg yolk lecithin, 10-21 parts of a chitosan aqueous solution, 4-16 parts of absolute ethyl alcohol and 160-185 parts of a weakly acidic buffer solution. When the fresh-keeping liquid provided by the invention is applied to the fresh-cut fruits and vegetables, an edible fresh-keeping film can be formed on the surfaces of the fresh-cut fruits and vegetables, evaporation of moisture on the surfaces of the fresh-cut fruits and vegetables can be reduced, respiration in tissues of the fresh-cut fruits and vegetables can be inhibited, the decay process of the fresh-cut fruits and vegetables can be delayed, and the components are safe and reliable.

This invention discloses a pH-responsive silk fibroin-doxacin prodrug nanoparticle, its preparation method, and its application. Silkworm cocoons are degummed, dissolved in a lithium bromide aqueous solution, and freeze-dried to obtain regenerated silk fibroin powder. The regenerated silk fibroin powder is then combined with succinic anhydride, a condensing agent, adipic dihydrazide, and doxorubicin hydrochloride, and treated multiple times with a composite solvent to prepare an aqueous solution of the silk fibroin-doxacin covalently bound. This solution is then added dropwise to an antisolvent under stirring to induce self-assembly into nanoparticles. After centrifugation purification and resuspension in water, the product is obtained. This invention completely overcomes the shortcomings of traditional physical encapsulation methods of silk fibroin, which are prone to burst release. The nanoparticles are extremely stable in physiological blood environments and can rapidly break hydrazone bonds for precise drug release in the slightly acidic environment of tumor cell endosomes. The antisolvent granulation mechanism promotes the flipping of unreacted polar groups to the surface, giving the nanoparticles a moderately negative potential and rich active sites, resulting in excellent colloidal stability and deep functionalization potential.

The invention provides an autolysis protective film triggered by double conditions in a wading environment and a preparation method of the autolysis protective film. The autolysis type protective film comprises an inner film layer and a composite hydrophobic barrier layer, wherein the inner film layer comprises a dynamic cross-linked network and a mechanical sensitive microcapsule; the composite hydrophobic barrier layer is composed of a hydrophobic agent sprayed or impregnated on the surface of the membrane; the preparation method comprises the following steps: firstly preparing the inner membrane layer and then carrying out hydrophobic barrier treatment; the protective film triggers autolysis under the double conditions of a wading environment and mechanical vibration with the frequency of 50-200 Hz and the amplitude larger than or equal to 0.2 mm, false triggering of the natural wading environment is avoided, and the protection reliability is improved. After being triggered, the microcapsule releases a decrosslinking agent, so that the inner membrane layer is promoted to be quickly dissolved, manual cleaning is not needed, the coating is suitable for underwater temporary protection and other scenes, and the barrier layer is safe, easy to degrade and environmentally friendly; the preparation method is simple in process, easy to operate, beneficial to industrial production, capable of improving efficiency and capable of reducing cost.

The application discloses a detection reagent and a detection method for fermentation power and acid production capacity of Daqu, and relates to the technical field of analysis and detection. The detection reagent comprises a sugar composition and an acid. The sugar composition is composed of glucose, maltose and sucrose, and the mass ratio of the glucose, the maltose and the sucrose is (4-18):(1-5):(0.1-1). The acid is at least one selected from acetic acid and lactic acid. The detection reagent of the application comprises glucose, maltose, sucrose and acid, and the acid is at least one selected from acetic acid and lactic acid. The application simplifies the components of the detection reagent, has the advantages of safe components, controllable safety, strong applicability and wide coverage, and makes the evaluation of the fermentation power and the acid production capacity of Daqu more accurate and efficient.