15results about How to "Reduce permeability" patented technology

This invention discloses a compound traditional Chinese medicine powder inhaler for respiratory tract infections and its preparation method, relating to the field of pharmaceutical formulation technology. The compound traditional Chinese medicine powder inhaler for respiratory tract infections is composed of polysaccharide composite gel microspheres, forsythia, scutellaria, honeysuckle, and isatis root. The polysaccharide composite gel microspheres are composed of seaweed sulfated polysaccharide, lentinan, calcium chloride, and curcumin. Seaweed sulfated polysaccharide, lentinan, curcumin, and calcium chloride cross-link to form a three-dimensional network spherical structure, improving the particle morphology and flowability of the micropowder. Furthermore, due to its good hygroscopic and moisturizing properties, it competitively reduces the moisture absorption of the micropowder, preventing aggregation and further improving flowability. In addition, the gel microspheres have excellent adhesion, adhering to the infection site after entering the respiratory tract, reducing expulsion losses due to respiration, maintaining an effective drug concentration at the infection site, and improving therapeutic efficacy.

The invention discloses essential oil microcapsule powder with high oil loading capacity and a preparation method thereof, and belongs to the technical field of microcapsules, the preparation method comprises the following steps: preparing a gelatin aqueous solution, preparing an Arabic gum aqueous solution, preparing an Arabic gum-starch aqueous solution, preparing a chitosan-tannic acid aqueous solution, preparing an emulsion, and performing primary crosslinking. Performing secondary crosslinking; the essential oil microcapsule powder prepared by the invention not only has high oil loading capacity and low surface oil content, but also has excellent slow release performance, solubility, long-term controlled release performance and flowability, and is uniform in particle size distribution.

The application discloses a kind of micro-fruit and vegetable fresh-keeping film preparation device and method, the device includes forming cylinder assembly, feeding coating component, dust generation and settlement component, air cooling device and film winding collection component;Forming cylinder assembly includes rotatable self-heating forming cylinder, feeding coating component is used to coat film-forming liquid on the left upper surface of self-heating forming cylinder, dust generation and settlement component is used to settle nano antibacterial catalyst dust on the film surface on self-heating forming cylinder;Air cooling device is used to cold blow setting on the film surface of the right lower part of self-heating forming cylinder, and film winding collection component is used to winding collection of the film formed.The device of the application utilizes the time window period of film not completely solidified to load nano catalytic functional powder, so that the powder is firmly attached to the film surface layer, the contact area of catalytic powder and oxygen is increased, the catalytic efficiency is improved, and the migration risk of catalytic powder is reduced.

The present application relates to the field of medicine and food, in particular to a novel application mode of astragalin. The present application provides a method for treating sepsis-related encephalopathy by using a medicine or preparation containing astragalin. Animal experiments show that astragalin can play a role in treating sepsis-related encephalopathy. It is found by the present application that astragalin can be used for preparing a medicine for treating sepsis-related encephalopathy.

The utility model discloses a balance block, and belongs to the technical field of compressors. The balance block comprises a low-magnetic-conductivity layer and a common steel layer, wherein the low-magnetic-conductivity layer and the common steel layer are formed by stacking a plurality of low-magnetic-conductivity layer sheets and common layer sheets respectively; one end or two ends of the balance block are of a regular or irregular structure, and the shape of the balance block is one or a combination of a semicircle, a square, a boot, a semi-willow leaf shape and an irregular polygon. According to the balance block and the manufacturing method thereof, the whole balance block is divided into a plurality of independent layer sheets, and a part of manufacturing materials of the balance block can be replaced by low-cost materials, so that the relative permeability mu r of the balance block can be kept below 1.05, the manufacturing cost of the balance block is greatly reduced, and the balance block is formed by stacking the plurality of layer sheets; the weight and the height of the whole balance block can be flexibly adjusted, and raw materials can be utilized to the maximum extent.

The utility model discloses a low-voltage upper clamping piece of a transformer, a clamping mechanism and the transformer, and relates to the technical field of transformer accessories, the low-voltage upper clamping piece of the transformer is provided with a top plate, a side plate and a bottom plate which are connected in sequence, the top plate, the side plate and the bottom plate define a groove with a notch back to a transformer iron core, and the notch and the side plate are oppositely arranged; the top plate is close to the top of the transformer iron core, and one side, back to the notch, of the side plate abuts against the transformer iron core; notches are formed in positions, corresponding to the low-voltage wire outlet heads on the low-voltage side, of the side plate and extend to the bottom plate; and a non-magnetic plate for blocking the notch is arranged in the notch. According to the low-voltage upper clamping piece, the notches are formed in the positions, corresponding to the low-voltage wire outlet heads, of the side plates of the low-voltage upper clamping piece, and the non-magnetic plates are arranged in the notches, so that heat generated by electromagnetic induction between the low-voltage wire outlet heads and the non-magnetic plates when the current of the low-voltage wire outlet heads is too large is reduced, the loss of a transformer is further reduced, and the service life of the transformer is prolonged. And safe and stable operation of the transformer is ensured.

The application provides a low-carbon high-manganese flux-cored wire and a preparation method thereof, and relates to the field of welding materials.The low-carbon high-manganese flux-cored wire comprises a steel belt sheath and a core material, the core material is filled in the steel belt sheath, and the core material comprises the following raw materials in terms of mass percentage: 36-45% of rutile, 2-4% of ferrotitanium, 4-6% of aluminum powder, 5-7% of manganese-silicon alloy, 6-8% of vanadium iron, 1-3% of nickel powder, 3-5% of molybdenum powder, 2-4% of sodium fluoride powder, 0.5-1% of rare earth ferrosilicon, 0.5-1% of high-boron iron, 2-3% of graphite, and the balance of atomized iron powder.The low-carbon high-manganese flux-cored wire and the preparation method thereof have the advantages that the flux-cored wire deposited metal has similar composition to that of 20Mn23Al, good weldability and excellent crack resistance, the matching of various elements in the flux-cored wire deposited metal also reduces the magnetic permeability, and the flux-cored wire is very suitable for the welding of 20Mn23Al structure, and has the advantages of low cost and long service life.

This invention belongs to the field of agricultural mulch film technology, specifically relating to a liquid mulch film and its preparation method. The liquid mulch film provided by this invention comprises the following raw materials: lignite ethanol extract, lignite-based humic acid, emulsifier, film-forming agent, plasticizer, and water. By combining lignite ethanol extract, lignite-based humic acid, film-forming agent, and plasticizer, the liquid mulch film provided by this invention can improve the hydrophobicity and toughness of the resulting liquid mulch film, thereby enhancing its heat retention and moisture retention effects on the soil.

The application relates to a magnetic suspension high-speed centrifugal compressor applied to the field of compressors. Through the arrangement of a water channel heat dissipation passage and an outer air channel heat dissipation passage, the compressor can be cooled from outside to inside, the temperature near the center rotor is reduced, the probability of the expansion deformation of the center rotor caused by overheating is effectively reduced, the inner air channel heat dissipation passage is arranged at the air gap between the center rotor and the stator, a large amount of heat near the air gap can be adsorbed, the low-temperature gas directly passes through the inner air channel heat dissipation passage to take away the heat, compared with the prior art, the targeted cooling of the air gap can be realized under the condition that the low-temperature gas does not directly contact the center rotor, the shaft jumping caused by the expansion deformation of the center rotor due to high temperature can be effectively reduced, the control difficulty of the bearing controller for maintaining the balance of the center rotor is not easily additionally increased due to the disturbance of the low-temperature gas, and the efficient operation of the compressor is effectively ensured.

This invention discloses a 3-trifluoromethyl-substituted pyrazole compound or a pharmaceutically acceptable salt thereof and its application. The 3-trifluoromethyl-substituted pyrazole compound or its pharmaceutically acceptable salt has the structure shown in formula (I). The 3-trifluoromethyl-substituted pyrazole compound or its pharmaceutically acceptable salt of this invention exhibits excellent inhibitory activity against PDE10A (phosphodiesterase type 10A), and compared to other phosphodiesterase subtypes, it shows high selectivity for phosphodiesterase type 10A, making it a specific drug for inhibiting phosphodiesterase type 10A activity. It also exhibits good metabolic stability, with a half-life of up to 239 min after metabolism by rat liver microsomes, solving the problem of excessively rapid metabolism of pyrazole PDE10A inhibitors such as MP-10.

This invention discloses a device and method for preparing a micro-atmosphere modified atmosphere (MAA) fruit and vegetable preservation film. The device includes a forming cylinder assembly, a feeding and coating assembly, a dust generation and settling assembly, an air-cooling device, and a film hoisting and collecting assembly. The forming cylinder assembly includes a rotatable self-heating forming cylinder. The feeding and coating assembly coats the film-forming liquid onto the upper left surface of the self-heating forming cylinder. The dust generation and settling assembly settles nano-antibacterial catalyst dust onto the film surface on the self-heating forming cylinder. The air-cooling device cools and shapes the film surface on the lower right side of the self-heating forming cylinder. The film hoisting and collecting assembly collects the formed film. This invention utilizes the time window before the film completely solidifies to load nano-catalytic functional powders, allowing the powders to adhere firmly to the film surface, increasing the contact area between the catalytic powders and oxygen, improving catalytic efficiency, and reducing the risk of catalytic powder migration.

The invention discloses a plant extract composition for resisting photo-thermal damage to skin and application of the plant extract composition. The composition is prepared by mixing the following raw materials in parts by weight: 60-90 parts of flos magnoliae biondii extract, 5-15 parts of saururus chinensis extract and 3-10 parts of eucommia ulmoides bark extract. Wherein the total lignan content in the flos magnoliae extract is greater than or equal to 8wt%; the content of total lignans in the saururus chinensis extract is greater than or equal to 15wt%, and the content of total triterpenes is greater than or equal to 25wt%; the content of coralline in the eucommia bark extract is greater than or equal to 8wt%, and the content of geniposide is greater than or equal to 2wt%. The composition has the advantages that the three plant extracts in the composition synergistically play a synergistic role in different key paths causing the photo-thermal injury of the skin, a complete theoretical logic closure is formed, the problem of skin redness caused by capillary vasodilation due to the photo-thermal injury can be synergistically solved, the safety is good, and the composition can be widely applied to cosmetics and external medicines.

The present application relates to a kind of synbiotic preparation, comprising: probiotic or its bacterial lysate, fermentation product, wherein probiotic is one or more selected from the following group: Bifidobacterium, Streptococcus, Lactobacillus, Saccharomycete, Escherichia coli;Prebiotic is one or more selected from the following group: breast milk oligosaccharide, fructo-oligosaccharide, inulin, lactulose, galacto-oligosaccharide, soybean oligosaccharide, resistant dextrin, xylo-oligosaccharide, isomalto-oligosaccharide, chitooligosaccharide;And wall material;The probiotic or its bacterial lysate, fermentation product is coupled with prebiotic, and wall material is wrapped in the coupling product.The synbiotic preparation of the application is simple, no chemical drug or antibiotic component is added, can repair damaged intestinal mucosal barrier, reduce intestinal permeability, regulate immune balance, optimize flora structure, so as to more effectively treat colitis.In addition, it is convenient to use, easy to promote in farm.

This invention, entitled "Application of 6-Methylcoumarin in the Preparation of Products for Treating Intestinal Diseases and Improving the Intestinal Barrier," belongs to the fields of biomedical technology and food. The technical problem to be solved is the poor safety, side effects, and drug resistance of existing IBD clinical drugs. The key technical solutions are the application of 6-methylcoumarin in the preparation of products that improve intestinal barrier function, its application as a treatment for intestinal barrier repair drugs, and its application as a treatment for intestinal barrier-related intestinal diseases.

The application belongs to the technical field of oral care products, and discloses a toothpaste composition for improving gum bleeding and a preparation method thereof. The composition is composed of targeted anti-inflammatory nanospheres, barrier repair composite agents, inactivated probiotic Lactobacillus plantarum and toothpaste basic auxiliary materials. The targeted anti-inflammatory nanospheres are hydroxypropyl-beta-cyclodextrin microspheres with ICAM-1 targeting peptides grafted on the surface, and the inside is embedded with active substances compounded from white wine and epigallocatechin gallate; the barrier repair composite agents are compounded from recombinant humanized collagen type III and sodium hyaluronate. The mild auxiliary material system without SLS can precisely enrich the active substances at the inflammation site of the gums, inhibit the inflammatory response, repair the gum epithelial barrier, regulate the balance of the oral microecology, effectively improve the gum bleeding and reduce the recurrence rate, and the active ingredients have good stability, low mucous membrane irritation and are suitable for long-term use of the vulnerable population of gums.