364 results about "Eczematous rash" patented technology

The invention discloses an application of betulinic acid 28-O-beta-D-glucoside (BA-6 for short) in preparation of a medicine for preventing and treating skin inflammation. The problems that an existing medicine for treating dermatitis is limited in curative effect, slow in effect taking, multiple in side effect, high in long-term use risk, large in individual difference, high in treatment cost, likely to cause immunoreaction and the like are solved. The invention discloses application of BA-6 in prevention and treatment of atopic dermatitis, contact dermatitis, eczema, rash, psoriasis, lupus erythematosus, papule squamous skin disease, pityriasis rosea, seborrheic dermatitis, pemphigus, celestial abscess, acne, tinea corporis, impetigo, SAPHO syndrome, hidradenitis suppurativa, dermatitis caused by drugs, lichen planus, pityriasis rubra pilaris, vitiligo, prurigo nodularis, dermatitis caused by drugs, and the like for the first time. The traditional Chinese medicine composition can be used for treating skin diseases, systemic sclerosis, hidradenitis suppurativa, granulomatous skin diseases, vitiligo, dermatomyositis, chronic skin itch and alopecia areata, and has the technical progress of obviously improving skin erythema, papule, edema, scale, moss and ulceration symptoms.

Provided are methods and composition for treating skin barrier functions and associated disorders. Formulated compositions may be applied on human skin to maintain a desired skin surface pH over an extended period of time without irritating the skin. Maintaining the desired surface pH aids in treatment of eczema, in addition to other skin conditions.

The present invention belongs to the technical field of medical catheters, and in particular, relates to a catheter care and fixing device for intravenous treatment, including an arm sleeve, a catheter guide clamping mechanism is fixedly installed on the upper end of the arm sleeve, a pressurizing fixing mechanism is fixedly installed on the arm sleeve, and a pressurizing confirmation mechanism connected to the pressurizing fixing mechanism is also fixedly installed on the outer wall of the arm sleeve. The present invention can prevent the catheter from being pulled and causing the catheter to move, thereby causing a greater impact on the patient, and can perform ventilation and dehumidification work at intervals between the arm sleeve and the patient's arm to avoid the arm sleeve pressing on the outside of the patient's arm, which will cause excessive sweat secretion on the skin, thereby causing skin redness, itching and eczema. It can automatically adjust the interval time of ventilation and dehumidification based on the thickness of the patient's arm, so as to meet the needs of patients with thicker arms to use higher frequency ventilation and dehumidification work.

The invention relates to a composition containing fermented peony seed oil and application of the composition in skin care products, and belongs to the technical field of skin care products, the composition is composed of 20-25 wt% of fermented peony seed oil, 2-4.5 wt% of a saw palmetto fruit extract, 4 wt% of a bitter melon fruit extract, 1.5 wt% of an abelmoschus esculentus fruit extract, 0.5-1 wt% of an emulsifier and the balance of deionized water, the fermented peony seed oil is prepared through a fermentation process, and fermentation strains comprise lactobacillus plantarum and bacillus licheniformis. The composition containing fermented peony seed oil provided by the invention does not contain chemical components with high irritation or high skin burden, is mild and non-irritant, can effectively improve eczema, has a remarkable effect, and is suitable for being used as an active component to be added into a skin care product.

The invention belongs to the technical field of external preparations, and provides compound itching-relieving cream as well as a preparation method and application thereof. The compound itching-relieving ointment is prepared from the following components in parts by weight: 3 to 6 parts of rhizoma coptidis, 9 to 15 parts of radix scutellariae, 9 to 15 parts of radix et rhizoma rhei, 3 to 6 parts of herba schizonepetae, 3 to 6 parts of herba menthae, 1 to 3 parts of cortex moutan, 1 to 3 parts of sandalwood and 0.5 to 1 part of borneol. The compound antipruritic ointment has the effects of cooling, relieving itching, detoxifying and diminishing swelling, and is used for treating itching and eczema dermatitis itching caused by biting of various small insects such as mosquitoes and the like. According to the compound antipruritic ointment disclosed by the invention, a plurality of components are in synergistic interaction, so that a multi-target and multi-layer treatment effect is realized. The traditional Chinese medicine composition can be used for cooling, relieving itching, detoxifying and diminishing swelling from the source while quickly relieving itching, and a comprehensive and effective solution is provided for itching.

The invention relates to the field of daily cosmetics, health care product raw materials and biology, and discloses lactobacillus rhamnosus JMB235 with the preservation number of CCTCC (China Center for Type Culture Collection) No.M 20232530. The fermentation product of lactobacillus rhamnosus has multiple effects, and can control grease secretion, prevent alopecia, inhibit acne, promote hair growth, inhibit eczema, inhibit inflammation, maintain skin barrier, promote epidermal cell proliferation and differentiation, block sun, repair damaged skin or improve insomnia. The compound can be used for preparing skin external preparations, health-care products, beautifying oral preparations, foods or food additives. And the fermentation product has good stability, is storable and has a wide application prospect.

Cosmetic composition comprising an endolysin and a compound of formula (I) The present invention relates to a composition, particularly a cosmetic one, comprising, in a physiologically acceptable medium, at least one endolysin, in particular an endolysin derived from a Staphylococcus aureus phage, and at least one compound of formula (I). It also relates to the use of such a composition to prevent and / or treat a skin disorder related to colonization by Staphylococcus aureus in an individual in need, in particular to prevent and / or treat acne and / or eczema in the individual, and a non-therapeutic cosmetic method for the care of keratinous materials, in particular skin, comprising at least one step of topical application of such a composition to said keratinous materials. Figure for abstract: None

The invention relates to a traditional Chinese medicine lotion for treating infantile eczema and a preparation method thereof. The traditional Chinese medicine lotion is prepared from the following raw materials in parts by weight: 20-40 parts of honeysuckle, 20-40 parts of cortex dictamni, 25-35 parts of cicada slough, 10-20 parts of raw mint, 13-23 parts of scutellaria baicalensis, 85-95 parts of vine of multiflower knotweed, 25-35 parts of fructus forsythiae, 22-32 parts of fried fructus aurantii, 25-35 parts of dandelion and 13-23 parts of raw liquorice. The traditional Chinese medicine composition follows the medication principle of monarch, minister, assistant and guide of traditional Chinese medicines, and the honeysuckle and the cortex dictamni in the formula are compatible to serve as monarch drugs. The cicada slough, the mint and the scutellaria baicalensis are compatible and are used as ministerial drugs. And the four raw materials including the vine of multiflower knotweed, the fructus forsythiae, the fructus aurantii and the dandelion are compatible and are used as adjuvant drugs. And liquorice is used as a conductant drug for harmonizing the medicines. The medicinal materials are combined to achieve the effects of dispelling wind, clearing heat, removing dampness and relieving itching, and the traditional Chinese medicine composition is suitable for various skin diseases such as urticaria, eczema, insect bite inflammation and allergic dermatitis caused by wind-heat rheumatism of children and infants, does not relapse after being treated, and avoids the side effects that many complications occur after hormone medicines are used for a long time and the skin diseases are prone to relapse after medicine withdrawal.

The invention belongs to the technical field of biological medicines, and particularly relates to a composition for treating atopic dermatitis and application thereof. The composition comprises the following components: pseudo-ginseng extract, artemether, alpine glycoside and oleanolic acid in a mass ratio of (2-4): (2-4): (1-2): (1-2). The composition disclosed by the invention has anti-inflammatory and anti-pruritus effects and can be used for treating atopic dermatitis, eczema and other diseases. The active components of the composition are all from plant sources, the composition has good safety and atopic dermatitis treatment efficacy, the use dosage is low, the components can achieve a synergistic interaction effect, and the composition shows an excellent effect; the composition can be applied to functional skin care products (face cream, emulsion and essence) and external medicines (applying agents and ointments).

Disclosed are a Pulsatilla saponin B4 derivative, a preparation method therefor, and a use thereof. A compound Pulsatilla saponin B4 (referred to as B4 or AB4) is used as a raw material, a nucleophilic substitution reaction, an electrophilic addition reaction, an esterification reaction, or an amidation reaction is separately performed on a C-19 exocyclic double bond or a C-28 carboxyl group to prepare a derivative, and the derivative is used as an active ingredient to prepare a drug having anti-inflammatory and immunomodulatory effects. In the present invention, it is disclosed for the first time that the B4 derivative has the effect of treating inflammatory diseases such as inflammatory bowel disease, atopic dermatitis, eczema, and psoriasis, and the effect is superior to that of B4 or a clinically common drug. In addition, it is also disclosed for the first time that most B4 derivatives do not show obvious cytotoxicity to macrophages, and can reduce the level of P-IκBa protein in LPS and ATP-induced macrophage NF-κB signaling pathways, inhibit the activation of NLRP3 signaling pathways and obviously reduce the level of Pro-IL-1β (p<0.05), i.e., inhibiting the activation of an inflammasome pathway, and the effect is superior to that of B4. These results show that the B4 derivative of the present invention has better anti-inflammatory activity.

A cosmetic composition comprising an endolysin and trehalose. The present invention relates to a composition, particularly a cosmetic one, comprising, in a physiologically acceptable medium, at least one endolysin, in particular an endolysin derived from a Staphylococcus aureus phage, and trehalose. It also relates to the use of such a composition to prevent and / or treat a skin disorder related to Staphylococcus aureus colonization in an individual in need, and in particular to prevent and / or treat acne and / or eczema in an individual in need, and a non-therapeutic cosmetic method for the care of keratinous materials, in particular skin, comprising at least one step of topical application of such a composition to said keratinous materials. Figure for abstract: None

1. Name of the product of this design: Ultraviolet light therapy pen (CN‑308P II). 2. Purpose of the product of this design: UV irradiation treatment for skin diseases such as vitiligo, psoriasis, pityriasis rosea, eczema, etc. 3. Key points of the design of this product: The combination of shape and pattern. 4. The picture or photo that best illustrates the key points of the design: Stereoscopic picture.

The invention discloses a pharmaceutical composition for treating atopic dermatitis and a preparation method and application of the pharmaceutical composition for treating atopic dermatitis. The pharmaceutical composition comprises matrix vaseline, a humectant, a moistening agent, a repairing agent and an antioxidant. Two lipid components (gamma-linolenic acid and linoleic acid) are supplemented, so that eczema-like dermatitis can be obviously relieved, skin lesion inflammatory cell infiltration is reduced, the content of fatty acid in a skin barrier is recovered, treatment of atopic dermatitis is assisted, and the treatment effect on the atopic dermatitis is remarkable; the pharmaceutical composition disclosed by the invention has the advantages of quick effect on atopic dermatitis, small toxic and side effects, good safety and good medicinal prospect.

The present invention relates generally to maqui berry for use in the treatment or prevention of skin diseases, wherein maqui berry may be the primary natural active ingredient. Particular embodiments as disclosed herein find application in, inter alia, the prophylaxis and the treatment of skin diseases, in particular, dermatitis, atopic dermatitis (neurodermatitis), dermatitis solaris, eczema, hand eczema, lichen planus, lupus erythematosus, psoriasis, urticaria, itching, scabies, age spot, freckles and dry / atopic skin of humans. In particular, the present invention relates to the use of maqui berry extract in the manufacture of a medicament or dietary supplement for use in treating or preventing said skin diseases or defects.

The invention belongs to the field of wash supplies, and provides a composition with functions of controlling oil, inhibiting bacteria, relieving itching and repairing ultraviolet damage and a facial cleanser. The composition is prepared from hydrolyzed keratin, recombinant collagen, zinc acetate, a rhizoma atractylodis macrocephalae extract, zingiber officinale roscoe essential oil and a fructus cnidii extract, and the mass ratio of the hydrolyzed keratin to the recombinant collagen to the zinc acetate to the rhizoma atractylodis macrocephalae extract to the zingiber officinale roscoe essential oil to the fructus cnidii extract is (3-3.2): (3-3.2): (1-1.2): (2-2.2): (2-2.2): (2-2.2). The facial cleanser contains the composition, and the mass fraction of the composition in the facial cleanser is 0.1%-5.0%. Experiments prove that the composition and the facial cleanser have good effects in the aspects of inhibiting skin sebum secretion, inhibiting bacteria, inhibiting eczema, inhibiting allergic rash, relieving itching, repairing ultraviolet damage and the like, and the problem that the comprehensive performance of the existing composition for facial skin and the related facial cleanser is not satisfactory can be solved.

The present invention provides a novel promoter for lipid synthesis in sebaceous gland cells. By using the novel promoter for lipid synthesis in sebaceous gland cells, a skin barrier damage repairing agent and cosmetics with a skin barrier damage repairing function can be prepared, so that cosmetics for repairing skin barrier damage of at least one type selected from skin dryness, premature skin aging, skin aging, skin pruritus, and senile sebaceous deficiency eczema caused by hypofunction of sebaceous glands and / or reduced sebum secretion can be developed.

The invention relates to the technical field of skin medicines, in particular to a pharmaceutical composition for preventing or treating inflammatory skin diseases and application. The invention discloses a pharmaceutical composition for preventing or treating inflammatory skin diseases and application. The composition comprises active ingredients of astacin and derivatives thereof, p-toluene sulfonamide and derivatives thereof, and pharmaceutically or cosmetically acceptable excipients. Through the synergistic effect of the two active components, the composition can effectively inhibit skin inflammatory response, relieve pruritus and erythema and promote skin barrier repair and wound healing. The composition can be prepared into multiple external dosage forms such as cream, gel and spray, is suitable for preventing or treating multiple inflammatory skin diseases such as atopic dermatitis, eczema and psoriasis, and can also be used for repairing and nursing skin wounds. The external formula provided by the invention has both curative effect and safety, and provides a new choice for the treatment of inflammatory dermatosis.

The invention relates to the technical field of treatment of eczema-like skin symptoms, in particular to an essential oil composition for treating eczema-like skin symptoms and application thereof, and the essential oil composition comprises the following components in parts by weight: 10-20 parts of lavender essential oil, 5-10 parts of tea tree essential oil, 30-40 parts of olive oil, 5-10 parts of squalane, 0.5-1 part of vitamin E and 1-5 parts of plant extract. The lavender essential oil and the tea tree essential oil are compounded, and the olive oil, the squalane, the vitamin E and the plant extract are supplemented, so that symptoms such as skin erythema, papule and pruritus caused by eczema can be effectively relieved, and good anti-inflammatory, antibacterial, moisturizing and repairing effects are achieved. The composition has the advantages of simple components, simplified preparation process, low production cost and wide application range, and can better meet clinical requirements.

Provided herein are compositions and their use for the treatment of human skin, particularly facial skin, to alleviate the symptoms of cosmetic or dermatologic skin conditions. The compositions include black willow bark extract, cat's claw extract, and dragon's blood extract. The compositions ameliorate skin conditions including acne, rosacea, blemish, dermatitis, eczema, or the like.

The present invention relates to the field of cosmetic technology, and specifically discloses an antibacterial soothing composition that can be used for children's eczema, and a preparation method and application thereof. An antibacterial soothing composition that can be used for children's eczema includes 30-50 parts of marshmallow root complex, 10-20 parts of Spanish sage seed complex, 20-30 parts of salvia root complex, 20-30 parts of difficile root bark complex and 20-30 parts of sanguisorba officinalis complex. An application of an antibacterial soothing composition that can be used for children's eczema is to add the antibacterial soothing composition that can be used for children's eczema to cosmetics. The antibacterial soothing composition of the present application can promote the growth of beneficial bacteria on the skin and inhibit the growth of pathogenic bacteria through the survival competition of colonies, restore the balance of skin microecology, enhance skin barrier ability and effectively resist skin inflammation, soothe the discomfort of the skin, and bring a gentle and comfortable use experience to users, especially children.

The invention relates to the technical field of medical care, in particular to a skin care composition as well as a preparation method and application thereof. The skin care composition is prepared from the following raw materials in percentage by mass: 0.05 to 5.0 percent of herba eupatorii extract, 0.01 to 2.0 percent of saussurea involucrata extract, 0.01 to 3.0 percent of bergamot extract and 90.0 to 99.93 percent of auxiliary materials. According to the skin care composition, the fortune eupatorium herb extract, the saussurea involucrata extract and the bergamot extract serve as main effective components, and the skin care composition can be used for treating formed bedsores and can also play a role in preventing long-term bedridden patients who do not form bedsores; the skin care composition is simple and convenient in preparation method, low in price and convenient in daily use, and greatly reduces the nursing work. And the traditional Chinese medicine composition also has effects on dry and chapped skin, eczema, diabetic foot and the like with similar diseases.

The invention relates to a portable traditional Chinese medicine drenching and soaking rapidly disintegrated and mixed effervescent tablet and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. The invention provides an effervescent tablet for treating eczematous dermatitis. The effervescent tablet is prepared from the following components in parts by mass: 10 to 40 parts of extract powder, 20 to 30 parts of citric acid, 15 to 25 parts of sodium bicarbonate, 1 to 3 parts of polyvinylpyrrolidone absolute ethyl alcohol solution, 1 to 9 parts of polyethylene glycol 6000, 15 to 30 parts of lactose and 3 to 7 parts of sodium carboxymethyl cellulose. The effervescent tablet obtained by the preparation method is convenient to use, convenient to carry and store, short in disintegration time, proper in pH value, large in foaming amount, smooth in appearance and clear in solution after disintegration, and the superfine powder for preparing the extract powder can improve the drug wall breaking rate, promote dissolution of effective components, improve the bioavailability and the treatment effect, improve the resource utilization rate and reduce the production cost. The invention provides a brand new dosage form of external medicine for treating eczematous dermatitis.

The present application relates to a peptide-ionic liquid conjugate for the prevention and / or treatment of skin conditions. The peptide-ionic liquid conjugate comprises a pharmaceutical cosmetic peptide containing up to 10 amino acids and at least one ionic liquid containing a C1 to C18 saturated or unsaturated hydrocarbon chain substituent. The peptide-ionic liquid conjugates disclosed herein are useful for combating skin conditions, such as melanoma, non-melanoma skin cancer, diabetic foot ulcer, lower limb vein ulcer, stress ulcer, acne, candidiasis, cellulitis, dermatophytosis, erysipelas, folliculitis, impetigo, psoriasis, rosacea or eczema (atopic dermatitis), and the like. As they exhibit potent activity, bactericidal effect, anti-inflammatory and immunomodulatory effect and collagen production inducing effect on antibiotic sensitive strains or gram-positive and gram-negative multi-drug resistant clinical isolates. The present application further discloses topical compositions comprising the peptide-ionic liquid conjugates and uses thereof.

The invention relates to the technical field of traditional Chinese pharmacology, and particularly discloses an external liquid containing lime and alum for astringing sores and a preparation method of the external liquid. The external liquid containing lime and alum for healing sores is prepared from the following raw materials: lime, alum, water, a thickening agent, a cortex phellodendri extract, carbonized sanguisorba root powder, borneol and a pH regulator. The preparation method comprises the following steps: S1, preparing lime milk; s2, preparing an alum solution; s3, mixing reaction; s4, performing curing treatment; s5, blending; s6, refining: filtering the mixture obtained in S5, adding borneol and ethylparaben into the filtrate before filtering, and uniformly stirring to obtain the external liquid for healing sore. The external liquid containing lime and alum for healing sores can be used for treating various skin injuries such as skin ulcers, wounds, burns, eczema and postoperative wounds, and has the advantages of efficient astringency and hemostasis, antisepsis and anti-inflammation, promotion of wound healing, good system stability, comfort in use and high safety.

The composition is composed of a herbal medicine alcohol extract and an alcohol solvent, the herbal medicine comprises Jinfo grass, radix angelicae, solidago decurrens, oldenlandia diffusa, fructus kochiae, fructus cnidii, bletilla striata, radix clematidis, cortex dictamni, portulaca grandiflora and gallnut, and the herbal medicine is scientifically proportioned according to the principle of monarch, minister and guide. The preparation method comprises the following steps: processing medicinal materials such as fructus cnidii, crushing, soaking with high-concentration alcohol according to a specific ratio, extracting, and finally filling into a spray bottle. The traditional Chinese medicine composition integrates multiple functions of disinfection, hemostasis, detumescence, pain relieving, itching relieving and the like, is suitable for multiple skin problems such as traumatic bleeding, burns and scalds, eczema and mosquito bites, and can be used for skin disinfection during epidemic situations so as to reduce epidemic risks. The product takes effect quickly, is convenient to use and is safe and effective, and the preparation process integrates tradition and efficiency.

The present invention relates to a flexible skin patch equipped with an ultra-thin LED assembly that emits light in a specific wavelength range and an invention for manufacturing the same, and is related to an invention capable of providing a flexible skin patch that has the excellent effect of promoting vitamin D production in a localized area of the skin, and has the effect of alleviating or treating local skin psoriasis, fungi, fungal tumors and eczema, and has excellent antiviral effect, and is easy to attach and detach.

This invention discloses a Tibetan bath composition compound and its preparation method, relating to the field of daily chemical products technology. The Tibetan bath composition compound consists of a ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder, Bacillus subtilis, Tibetan medicine composition, starch, anhydrous citric acid, sodium bicarbonate, calcium citrate, crospovidone, and magnesium stearate. Bacillus subtilis is used to ferment the ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder to obtain a fermentation-modified porous carrier, which is then loaded with the Tibetan medicine composition to form a Tibetan medicine inclusion powder. This not only achieves efficient drug delivery through a triple mechanism of biomodification, metabolite synergy, and structural optimization, but also forms a quaternary system with Terminalia chebula. The effervescent effect also enhances the penetration of Tibetan medicine components, which is beneficial for better exerting the antibacterial and anti-inflammatory effects of active substances, and significantly improving fungal infections and eczema-related skin problems.

A method of treating moderate to severe chronic hand eczema in a human patient comprising twice daily administration to the skin of said human patient in need thereof of an acidified aqueous topical composition comprising comprises 20 mg / g delgocitinib on a free base basis or a pharmaceutically acceptable salt.

The present disclosure is related to a topical formulation comprising clascoterone in a mixture of aqueous and oily gel phases. The present disclosure further relates to a method of treating or preventing skin conditions such acne vulgaris, acne conglobata, acne fulminans, androgenetic alopecia, hidradenitis suppurativa (also known as acne inversa), hirsutism, cancer-therapy-induced rash, eczema, rosacea, atopic dermatitis, psoriasis, inverse psoriasis, seborrheic dermatitis, acanthosis nigricans, wound, and female pattern hair loss, comprising topically administering to a subject in need thereof an effective amount of the formulation.

The present invention relates to a pharmaceutical composition and method for treating skin conditions. The composition comprises a hydrogel film containing an effective amount of at least one active ingredient selected from hydrolyzed collagen, sodium hyaluronate, aloe barbadensis leaf extract, tocopheryl acetate, and rosa rugosa flower oil, along with one or more gelling agents capable of forming a co-polymer network. The hydrogel film is configured to adhere to the skin and deliver the active ingredient in a targeted and prolonged manner. The method involves applying the film to an affected area of the skin for a period sufficient to treat conditions such as sunburn, dryness, and eczema. The invention provides a convenient and effective means of delivering active ingredients directly to the skin while maintaining the structural integrity of the film during use.