125 results about "Eczematous rash" patented technology

The invention relates to a composition containing fermented peony seed oil and application of the composition in skin care products, and belongs to the technical field of skin care products, the composition is composed of 20-25 wt% of fermented peony seed oil, 2-4.5 wt% of a saw palmetto fruit extract, 4 wt% of a bitter melon fruit extract, 1.5 wt% of an abelmoschus esculentus fruit extract, 0.5-1 wt% of an emulsifier and the balance of deionized water, the fermented peony seed oil is prepared through a fermentation process, and fermentation strains comprise lactobacillus plantarum and bacillus licheniformis. The composition containing fermented peony seed oil provided by the invention does not contain chemical components with high irritation or high skin burden, is mild and non-irritant, can effectively improve eczema, has a remarkable effect, and is suitable for being used as an active component to be added into a skin care product.

The invention belongs to the technical field of external preparations, and provides compound itching-relieving cream as well as a preparation method and application thereof. The compound itching-relieving ointment is prepared from the following components in parts by weight: 3 to 6 parts of rhizoma coptidis, 9 to 15 parts of radix scutellariae, 9 to 15 parts of radix et rhizoma rhei, 3 to 6 parts of herba schizonepetae, 3 to 6 parts of herba menthae, 1 to 3 parts of cortex moutan, 1 to 3 parts of sandalwood and 0.5 to 1 part of borneol. The compound antipruritic ointment has the effects of cooling, relieving itching, detoxifying and diminishing swelling, and is used for treating itching and eczema dermatitis itching caused by biting of various small insects such as mosquitoes and the like. According to the compound antipruritic ointment disclosed by the invention, a plurality of components are in synergistic interaction, so that a multi-target and multi-layer treatment effect is realized. The traditional Chinese medicine composition can be used for cooling, relieving itching, detoxifying and diminishing swelling from the source while quickly relieving itching, and a comprehensive and effective solution is provided for itching.

The present invention relates generally to maqui berry for use in the treatment or prevention of skin diseases, wherein maqui berry may be the primary natural active ingredient. Particular embodiments as disclosed herein find application in, inter alia, the prophylaxis and the treatment of skin diseases, in particular, dermatitis, atopic dermatitis (neurodermatitis), dermatitis solaris, eczema, hand eczema, lichen planus, lupus erythematosus, psoriasis, urticaria, itching, scabies, age spot, freckles and dry / atopic skin of humans. In particular, the present invention relates to the use of maqui berry extract in the manufacture of a medicament or dietary supplement for use in treating or preventing said skin diseases or defects.

The invention belongs to the field of wash supplies, and provides a composition with functions of controlling oil, inhibiting bacteria, relieving itching and repairing ultraviolet damage and a facial cleanser. The composition is prepared from hydrolyzed keratin, recombinant collagen, zinc acetate, a rhizoma atractylodis macrocephalae extract, zingiber officinale roscoe essential oil and a fructus cnidii extract, and the mass ratio of the hydrolyzed keratin to the recombinant collagen to the zinc acetate to the rhizoma atractylodis macrocephalae extract to the zingiber officinale roscoe essential oil to the fructus cnidii extract is (3-3.2): (3-3.2): (1-1.2): (2-2.2): (2-2.2): (2-2.2). The facial cleanser contains the composition, and the mass fraction of the composition in the facial cleanser is 0.1%-5.0%. Experiments prove that the composition and the facial cleanser have good effects in the aspects of inhibiting skin sebum secretion, inhibiting bacteria, inhibiting eczema, inhibiting allergic rash, relieving itching, repairing ultraviolet damage and the like, and the problem that the comprehensive performance of the existing composition for facial skin and the related facial cleanser is not satisfactory can be solved.

The invention relates to the technical field of skin medicines, in particular to a pharmaceutical composition for preventing or treating inflammatory skin diseases and application. The invention discloses a pharmaceutical composition for preventing or treating inflammatory skin diseases and application. The composition comprises active ingredients of astacin and derivatives thereof, p-toluene sulfonamide and derivatives thereof, and pharmaceutically or cosmetically acceptable excipients. Through the synergistic effect of the two active components, the composition can effectively inhibit skin inflammatory response, relieve pruritus and erythema and promote skin barrier repair and wound healing. The composition can be prepared into multiple external dosage forms such as cream, gel and spray, is suitable for preventing or treating multiple inflammatory skin diseases such as atopic dermatitis, eczema and psoriasis, and can also be used for repairing and nursing skin wounds. The external formula provided by the invention has both curative effect and safety, and provides a new choice for the treatment of inflammatory dermatosis.

The invention relates to the technical field of treatment of eczema-like skin symptoms, in particular to an essential oil composition for treating eczema-like skin symptoms and application thereof, and the essential oil composition comprises the following components in parts by weight: 10-20 parts of lavender essential oil, 5-10 parts of tea tree essential oil, 30-40 parts of olive oil, 5-10 parts of squalane, 0.5-1 part of vitamin E and 1-5 parts of plant extract. The lavender essential oil and the tea tree essential oil are compounded, and the olive oil, the squalane, the vitamin E and the plant extract are supplemented, so that symptoms such as skin erythema, papule and pruritus caused by eczema can be effectively relieved, and good anti-inflammatory, antibacterial, moisturizing and repairing effects are achieved. The composition has the advantages of simple components, simplified preparation process, low production cost and wide application range, and can better meet clinical requirements.

Provided herein are compositions and their use for the treatment of human skin, particularly facial skin, to alleviate the symptoms of cosmetic or dermatologic skin conditions. The compositions include black willow bark extract, cat's claw extract, and dragon's blood extract. The compositions ameliorate skin conditions including acne, rosacea, blemish, dermatitis, eczema, or the like.

The invention relates to the technical field of traditional Chinese pharmacology, and particularly discloses an external liquid containing lime and alum for astringing sores and a preparation method of the external liquid. The external liquid containing lime and alum for healing sores is prepared from the following raw materials: lime, alum, water, a thickening agent, a cortex phellodendri extract, carbonized sanguisorba root powder, borneol and a pH regulator. The preparation method comprises the following steps: S1, preparing lime milk; s2, preparing an alum solution; s3, mixing reaction; s4, performing curing treatment; s5, blending; s6, refining: filtering the mixture obtained in S5, adding borneol and ethylparaben into the filtrate before filtering, and uniformly stirring to obtain the external liquid for healing sore. The external liquid containing lime and alum for healing sores can be used for treating various skin injuries such as skin ulcers, wounds, burns, eczema and postoperative wounds, and has the advantages of efficient astringency and hemostasis, antisepsis and anti-inflammation, promotion of wound healing, good system stability, comfort in use and high safety.

The composition is composed of a herbal medicine alcohol extract and an alcohol solvent, the herbal medicine comprises Jinfo grass, radix angelicae, solidago decurrens, oldenlandia diffusa, fructus kochiae, fructus cnidii, bletilla striata, radix clematidis, cortex dictamni, portulaca grandiflora and gallnut, and the herbal medicine is scientifically proportioned according to the principle of monarch, minister and guide. The preparation method comprises the following steps: processing medicinal materials such as fructus cnidii, crushing, soaking with high-concentration alcohol according to a specific ratio, extracting, and finally filling into a spray bottle. The traditional Chinese medicine composition integrates multiple functions of disinfection, hemostasis, detumescence, pain relieving, itching relieving and the like, is suitable for multiple skin problems such as traumatic bleeding, burns and scalds, eczema and mosquito bites, and can be used for skin disinfection during epidemic situations so as to reduce epidemic risks. The product takes effect quickly, is convenient to use and is safe and effective, and the preparation process integrates tradition and efficiency.

The present invention relates to a flexible skin patch equipped with an ultra-thin LED assembly that emits light in a specific wavelength range and an invention for manufacturing the same, and is related to an invention capable of providing a flexible skin patch that has the excellent effect of promoting vitamin D production in a localized area of the skin, and has the effect of alleviating or treating local skin psoriasis, fungi, fungal tumors and eczema, and has excellent antiviral effect, and is easy to attach and detach.

This invention discloses a Tibetan bath composition compound and its preparation method, relating to the field of daily chemical products technology. The Tibetan bath composition compound consists of a ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder, Bacillus subtilis, Tibetan medicine composition, starch, anhydrous citric acid, sodium bicarbonate, calcium citrate, crospovidone, and magnesium stearate. Bacillus subtilis is used to ferment the ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder to obtain a fermentation-modified porous carrier, which is then loaded with the Tibetan medicine composition to form a Tibetan medicine inclusion powder. This not only achieves efficient drug delivery through a triple mechanism of biomodification, metabolite synergy, and structural optimization, but also forms a quaternary system with Terminalia chebula. The effervescent effect also enhances the penetration of Tibetan medicine components, which is beneficial for better exerting the antibacterial and anti-inflammatory effects of active substances, and significantly improving fungal infections and eczema-related skin problems.

A method of treating moderate to severe chronic hand eczema in a human patient comprising twice daily administration to the skin of said human patient in need thereof of an acidified aqueous topical composition comprising comprises 20 mg / g delgocitinib on a free base basis or a pharmaceutically acceptable salt.

The present disclosure is related to a topical formulation comprising clascoterone in a mixture of aqueous and oily gel phases. The present disclosure further relates to a method of treating or preventing skin conditions such acne vulgaris, acne conglobata, acne fulminans, androgenetic alopecia, hidradenitis suppurativa (also known as acne inversa), hirsutism, cancer-therapy-induced rash, eczema, rosacea, atopic dermatitis, psoriasis, inverse psoriasis, seborrheic dermatitis, acanthosis nigricans, wound, and female pattern hair loss, comprising topically administering to a subject in need thereof an effective amount of the formulation.

The present invention relates to a pharmaceutical composition and method for treating skin conditions. The composition comprises a hydrogel film containing an effective amount of at least one active ingredient selected from hydrolyzed collagen, sodium hyaluronate, aloe barbadensis leaf extract, tocopheryl acetate, and rosa rugosa flower oil, along with one or more gelling agents capable of forming a co-polymer network. The hydrogel film is configured to adhere to the skin and deliver the active ingredient in a targeted and prolonged manner. The method involves applying the film to an affected area of the skin for a period sufficient to treat conditions such as sunburn, dryness, and eczema. The invention provides a convenient and effective means of delivering active ingredients directly to the skin while maintaining the structural integrity of the film during use.

A method of treating moderate to severe chronic hand eczema in a human patient comprises administering to the skin of the human patient in need thereof an acidified aqueous topical composition comprising 20 mg / g of free base-based digotinib, or a pharmaceutically acceptable salt thereof, twice a day.

The present invention relates to a composition, in particular a cosmetic composition, comprising, in a physiologically acceptable medium, at least one endolysin derived from Staphylococcus aureus bacteriophage and at least one oil other than liquid paraffin. The invention also relates to the use of such a composition for the prevention and / or treatment of skin conditions associated with colonization of Staphylococcus aureus in a subject in need thereof, and in particular for the prevention and / or treatment of acne and / or eczema in a subject, and to a non-therapeutic cosmetic method for caring for keratin materials, in particular skin, it comprises at least one step of topically applying such a composition to the keratin material.

The invention relates to the technical field of medicines, and particularly discloses a polypeptide Loni-P extracted from traditional Chinese medicine honeysuckle, and the amino acid sequence of the polypeptide Loni-P is SEQ ID No.1. The polypeptide can be prepared from honeysuckle through the steps of ultrasonication, enzymolysis, purification and the like. Experiments show that the inhibition rate of Loni-P to malassezia under the concentration of 2 mu g / mL reaches 86 + / -5.29%, which is similar to that of positive control ketoconazole (92 + / -9.17%). The invention further provides a medicated bath component containing Loni-P. The medicated bath component is composed of polypeptide, beta-cyclodextrin, chitosan, fumaric acid, sodium hydroxide and other auxiliary materials and is matched with 200 L of medicated bath water. Clinical experiments show that the medicated bath can remarkably relieve itching, skin lesion area and shape of a chronic eczema patient, and after 30 days of treatment, the score of an experimental group is reduced from 7.93 to 4.0 (a control group has no remarkable change). The polypeptide is natural in source and high in safety, and a new strategy is provided for eczema treatment.

The invention discloses a pediatric eczema treatment ointment applying device, and belongs to the technical field of pediatric treatment, the pediatric eczema treatment ointment applying device comprises an ointment applying device body, and the inner side of the ointment applying device body is provided with a medicine extruding assembly used for extruding ointment contained in a medicine containing pipe; a cleaning assembly used for cleaning the skin eczema position is arranged on the lower side of the medicine applying device body, an installing and fixing assembly used for installing and fixing the medicine containing pipe is arranged on the inner side of the medicine applying device body, and a detaching and replacing assembly used for detaching the cleaning assembly and the even scraping assembly independently or together is arranged on the outer side of the medicine applying device body. In practical application, a single doctor can independently complete the whole medicine applying process, the cleaning assembly, the medicine squeezing assembly and the uniform scraping assembly cooperate to enable the doctor to orderly perform cleaning, medicine applying and uniform scraping on the eczema part on the premise that the device is held by one hand, a child patient does not need to be fixed or tools do not need to be frequently replaced with the help of others, and the operation is simple and convenient. The labor demand is greatly reduced, and the medicine feeding efficiency is improved.

The invention discloses a composition with soothing, red fading and barrier repairing functions and application thereof. The composition is prepared from the following raw materials in parts by mass: 0.01 to 0.1 part of fructus hippophae extract, 0.01 to 1 part of flos magnoliae extract and 1 to 5 parts of egg oil. The composition can be applied to cosmetics. The fructus hippophae extract, the flos magnoliae extract and the egg oil are compounded according to a certain mass ratio and then are used as effective components of cosmetics, the composition has the effects of increasing the epidermis moisture content, relieving and fading red and repairing a barrier, and the raw materials of the composition are natural, green, high in safety, mild and non-irritating, and the composition has a good application prospect. The skin care product has good smearing absorption performance, the skin feeling of the skin care product can be effectively improved, the smearing ductility of the product and the softness of the dried skin are improved, and the sticky feeling of the product is reduced; the traditional Chinese medicine composition not only can effectively relieve skin sensitivity and discomfort of adults, but also can be used for relieving eczema, dry and red skin and other problems of infants.

Provided are methods of providing a cooling sensation to skin afflicted with eczema, the methods comprising topically applying to skin afflicted with eczema a composition comprising isododecane.

The invention discloses a fibroblast preparation and a preparation method and application thereof, and belongs to the technical field of biomedical engineering, and the fibroblast preparation is prepared by mixing and compounding fibroblasts, a carrier and an active substance solution. The preparation method comprises the following steps: S1, cell pretreatment; s2, preparing a cross-linked collagen fiber hydrogel; s3, preparing an active substance solution; and S4, preparing the fibroblast preparation. By pretreating fibroblasts, activating the anti-inflammatory phenotype of the fibroblasts, promoting the fibroblasts to secrete collagen, loading the cells through collagenous fiber hydrogel and adding active substances, the skin lesion is repaired, meanwhile, type II immune excessive activation is inhibited, and the clinical disease performance of eczema mice is remarkably improved. The problems of limited skin disease treatment and skin lesion repair effects caused by low cell survival rate, poor carrier biocompatibility and poor active substance synergism in the prior art are solved, and the preparation method has the potential of preparing drugs for treating skin diseases.

The invention discloses a traditional Chinese medicine composition for treating diabetic skin itch and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The composition is prepared from angelica sinensis, astragalus membranaceus, radix paeoniae rubra, cortex dictamni, rehmannia, ligusticum wallichii, scalded peach kernels, safflower carthamus, fried tribulus terrestris, divaricate saposhnikovia roots and cicada slough according to a specific weight ratio. On the basis of a classic famous formula of the Chinese angelica potion, the Chinese angelica potion is innovatively prepared aiming at the core pathogenesis of qi deficiency, blood stasis, damp-heat and wind-dryness of diabetic skin itch. The radix paeoniae rubra and the radix paeoniae alba are used for enhancing the effects of cooling blood and dissipating blood stasis; peach kernel and safflower are added to strengthen blood circulation activation and collateral dredging; cortex dictamni is added to enhance dampness eliminating and detoxification; cicada slough and herba schizonepetae are used for enhancing wind dispelling and heat clearing, and the nature is Polygonum multiflorum and liquorice are removed, so that the safety is improved. The whole formula has the effects of tonifying qi, promoting blood circulation, eliminating dampness, detoxifying, dispelling wind and moistening dryness. The invention also provides a preparation method of the composition. The composition can be used for preparing medicines for treating skin diseases such as diabetic skin itch and eczema, and is remarkable in curative effect and high in safety.

The utility model relates to the technical field of shoulder joint orthosis, and discloses a shoulder joint orthosis with good air permeability, which comprises a side plate, a first support plate is movably hinged to the left side of the top end of the side plate, and a second support plate is arranged on the left side of the first support plate. According to the shoulder joint orthosis with the good air permeability, the protection pad, the waist protection pad and the second ventilation holes are arranged, lyocell fibers are natural plant fibers and have the advantages of being natural in gloss, smooth in hand feeling, high in strength, good in moisture permeability and air permeability and the like, and the second ventilation holes and the first ventilation holes can further improve the air permeability of the waist protection pad and other assemblies; the problems of skin itch, skin eczema, chronic dermatitis and the like caused by air tightness after wearing are prevented, so that the air permeability of the shoulder joint orthosis is improved, a patient can be protected, the comfort of the patient during use is improved, and the problems that the air permeability of the shoulder joint orthosis is poor, and skin itch of the patient is likely to be caused are solved.

In some embodiments, a composition comprising an effective amount of Bifidobacterium breve, Bifidobacterium bifidum, and Lactobacillus salivarius is provided. In some embodiments, the use of the composition in the prevention or treatment of atopic eczema in a subject is provided. In some embodiments, there is provided a method of preventing or treating atopic eczema in a subject, the method comprising the step of administering to the subject an effective amount of the composition. In some embodiments, there is provided a kit comprising: a composition of any one of the examples herein; and at least one container selected from the group consisting of capsules, pouches, packets, sachets, bottles, and blister packages. Other exemplary embodiments are described herein. In certain embodiments, the compositions are safe to use and effective to prevent or treat atopic eczema in a subject, especially an adult subject.

This invention belongs to the field of medical catheter technology, specifically a catheter fixation device, including an arm sleeve. An airbag is fixedly connected to the inner ring of the arm sleeve, and a catheter positioning component is disposed on the arm sleeve. The catheter positioning component includes a grooved plate fixedly connected to one side of the outer ring of the arm sleeve, with clamping blocks slidably connected to both sides of the groove. A sweat-absorbing component is also disposed on the arm sleeve. The sweat-absorbing component includes a rotating ring rotatably disposed within the inner cavity of the arm sleeve, with a support block fixedly connected to one side of the rotating ring. This invention utilizes the sweat-absorbing component to absorb excessive sweat secretion at the point where the patient's skin contacts the airbag. This is achieved by driving the moisture-absorbing roller to adhere to the patient's skin, thus avoiding excessive sweat secretion caused by the airbag pressing against the patient's arm, which can lead to skin redness, itching, and eczema.

A multi-purpose medicinal cream comprising shea butter, wild opium lettus powder, Orange Blood, Frankincense, Lavender, Rosemary, Copaiba Balsam, Birch Sweet, Lemon Grass, Marjoram, Basil, Eucalyptus, Peppermint, Cinnamon, Cedarwood, Thyme, Clove, Vetiver, Geranium, Cinnamon Leaf, and Ylang Ylang. The multi-purpose cream is an aid in pain management of disorders including lupus, arthritis, rheumatoid arthritis, knee and joint pain, neck pain, inflammation, migraines, and neuropathic disorders, as well the treatment of skin conditions including eczema, dry skin, psoriasis, swelling, heat rash, rashes, and rashes of dogs.

This invention discloses a compound ointment for protecting the nasal mucosa and repairing skin damage, and its preparation method, belonging to the field of pharmaceutical technology. The compound ointment is formulated with Sophora japonica fruit extract, erythromycin ointment, vitamin B6, levofloxacin hydrochloride tablets, loratadine tablets, fluticasone propionate nasal spray, sesame oil, and honey in specific weight proportions. The components work synergistically, providing protection for the nasal mucosa, treatment of rhinitis, reduction of cold air and external pollutant intrusion, and prevention of colds. It can also treat hemorrhoids, scars, eczema, and other skin damage, achieving "one medicine for multiple uses." This compound ointment has a stable dosage form, is convenient to use, has high utilization rate, high safety, and no obvious side effects, making it suitable for various populations and possessing good industrialization prospects.

The invention relates to a pharmaceutical composition and a preparation for treating children eczema, and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The pharmaceutical composition for treating children eczema is prepared from rhizoma smilacis glabrae, fructus kochiae, cortex phellodendri, radix sophorae flavescentis and dried alum, and has the effects of tonifying spleen, removing dampness, clearing away heat and toxic materials, dispelling wind and arresting itching; the rhizoma smilacis glabrae is a monarch drug for clearing away heat and toxic materials The fructus kochiae has the effects of clearing heat, promoting diuresis, dispelling wind and arresting itching, the cortex phellodendri has the effects of purging fire, removing steam, detoxifying and treating sores, and the radix sophorae flavescentis has the effects of clearing heat, drying dampness and killing parasites to relieve itching; dried alum is used for astringing dampness and relieving itching. Compared with the existing medicine for treating infantile eczema, the medicine composition disclosed by the invention is good in treatment effect, simple in preparation process and convenient to carry and use; and side effects caused by the use of chemicals can be avoided.

The invention discloses a pharmaceutical composition for treating eczema, application of the pharmaceutical composition and an external preparation based on the pharmaceutical composition, and belongs to the technical field of traditional Chinese medicines. Three medicinal materials including dandelion, polygonum aviculare and polygonum flaccidum are taken as raw materials, water and ethanol with different concentrations are taken as extraction solvents, the extracted extracts are taken as active ingredients of external preparations such as lotion, cream, gel and cream, the itching relieving effect can be quickly and effectively achieved through combination of the active ingredients, and the traditional Chinese medicine composition is suitable for treating eczema and has a wide application prospect. The symptoms of eczema scabbing, redness and swelling and pruritus are remarkably improved, and eczema is not prone to And the preparation is simple in process and suitable for industrial production.

The present disclosure provides methods and compositions for treating a disease or condition involving inflammation in the skin, e.g., atopic dermatitis, eczema other than atopic dermatitis, hidradenitis suppurativa, vitiligo, alopecia areata, scleroderma (including systemic sclerosis), dermatomyositis, epidermolysis bullosa, mastocytosis, keloids, acne, rosacea, or bullous pemphigoid, with a therapeutic dose of an anti-TNF-like ligand 1A (TL1A) antibody (Afimkibart).