21 results about "Eczematous rash" patented technology

This invention discloses a Tibetan bath composition compound and its preparation method, relating to the field of daily chemical products technology. The Tibetan bath composition compound consists of a ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder, Bacillus subtilis, Tibetan medicine composition, starch, anhydrous citric acid, sodium bicarbonate, calcium citrate, crospovidone, and magnesium stearate. Bacillus subtilis is used to ferment the ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder to obtain a fermentation-modified porous carrier, which is then loaded with the Tibetan medicine composition to form a Tibetan medicine inclusion powder. This not only achieves efficient drug delivery through a triple mechanism of biomodification, metabolite synergy, and structural optimization, but also forms a quaternary system with Terminalia chebula. The effervescent effect also enhances the penetration of Tibetan medicine components, which is beneficial for better exerting the antibacterial and anti-inflammatory effects of active substances, and significantly improving fungal infections and eczema-related skin problems.

This invention discloses a compound ointment for protecting the nasal mucosa and repairing skin damage, and its preparation method, belonging to the field of pharmaceutical technology. The compound ointment is formulated with Sophora japonica fruit extract, erythromycin ointment, vitamin B6, levofloxacin hydrochloride tablets, loratadine tablets, fluticasone propionate nasal spray, sesame oil, and honey in specific weight proportions. The components work synergistically, providing protection for the nasal mucosa, treatment of rhinitis, reduction of cold air and external pollutant intrusion, and prevention of colds. It can also treat hemorrhoids, scars, eczema, and other skin damage, achieving "one medicine for multiple uses." This compound ointment has a stable dosage form, is convenient to use, has high utilization rate, high safety, and no obvious side effects, making it suitable for various populations and possessing good industrialization prospects.

Provided herein are methods for diagnosis and treatment of chronic hand eczema (CHE) using skin surface biomarkers. The methods include obtaining from a subject skin samples, detecting certain biomarkers, determining the levels of the biomarkers, comparing the levels to reference levels, and determining whether the subject has CHE.

The present application relates to the technical field of Mongolian medicine external preparation, in particular to a Mongolian medicine Sendeng-4 cream. The cream is prepared from Sendeng, Terminalia chebula, Gardenia jasminoides and Chinese Hopea as raw materials, and effective components are enriched by composite enzymolysis, supercritical CO2 two-phase extraction, gradient membrane separation and molecular imprinting purification. Then, the cream is prepared by adding composite penetration enhancer and plant source preservative after the pH-ROS response carrier targets drug loading and the temperature-sensitive composite matrix is microfluidic adapted. The present application solves the defects of traditional preparation, such as insufficient dissolution, poor stability and weak targeting, and has high cream purity, good skin permeability, excellent safety, stable long-term storage performance, and is suitable for skin inflammation, eczema, itching and other diseases. The cream has the advantages of traditional Mongolian medicine and modern preparation, and has a wide clinical application prospect.

This invention discloses a long-acting antipruritic and antibacterial topical skin preparation, comprising N-ethyl-γ-L-glutamine, 1-1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphate-N-(L-γ-glutamyl-N-ethyl)-ethanolamine (POPE-N-Et-Gln-α), chlorhexidine acetate, and saffron extract as active ingredients, formulated into a hydrogel or cream with a pharmaceutically acceptable matrix. POPE-N-Et-Gln-α provides rapid transdermal action, while N-ethyl-γ-L-glutamine offers sustained-release and long-lasting effects; saffron extract provides anti-inflammatory and antioxidant effects, and chlorhexidine acetate provides antibacterial and antifungal effects. This invention is hormone-free and non-addictive, achieving both rapid and long-lasting antipruritic effects, and is suitable for eczema, urticaria, dry skin, neurodermatitis, psoriasis, microbial infections, and skin itching caused by insect bites.

L'Oréal Cosmetic Composition Comprising an Endolysin Derived from a Staphylococcus aureus Phage and 4-Hydroxyacetophenone. The present invention relates to a composition, particularly a cosmetic one, comprising, in a physiologically acceptable medium, at least one endolysin derived from a Staphylococcus aureus phage and 4-hydroxyacetophenone. It also relates to the use of such a composition to prevent and / or treat a skin disorder related to colonization by Staphylococcus aureus in an individual in need, and in particular to prevent and / or treat acne and / or eczema in an individual in need, and a non-therapeutic cosmetic method for the care of keratinous materials, particularly skin, comprising at least one step of topical application of such a composition to said keratinous materials. Figure for abstract: None

This invention provides a method for preparing natural nanophases of a Uyghur medicine compound preparation for treating eczema and its application. Based on a patent (CN201911308259.1) for a compound preparation for treating skin inflammation, this method regulates the solvent composition, concentration conditions, and mixing method of the extraction system to form a stable multiphase structure. Further, differential centrifugation is used to achieve directional separation of phases with different particle sizes, thereby obtaining natural nanophases. The obtained natural nanophases enrich the active ingredients in the compound preparation, significantly reduce cytotoxicity, and enhance biocompatibility. Simultaneously, they significantly inhibit NO production and exhibit eczema-related antibacterial activity, improving drug absorption and utilization efficiency, thus demonstrating superior eczema-related biological activity. This method also addresses the issue of the darker color of the product obtained from the original preparation process, improving the acceptability of the preparation and medication adherence.

A fire-retardant topical formulation comprising glycerol and urea in a ratio of 1:1 to 1:30 is provided. The formulation may further comprise polyvinyl pyrrolidone and / or ethylhexylglycerin, and / or a barrier forming agent and / or a stabilising agent. The formulation may be a moisturiser, shampoo, conditioner, hair dye, sun cream, aftersun composition, emollient or medical composition. The formulation may be for use in treating a skin condition, such as eczema, dermatitis, psoriasis, elderly dry and itchy skin, ichthyosis, rash, or infection. The composition when transferred to a fabric suppresses the flammability of the fabric and is also capable of being removed from the fabric by washing. A preferred formulation comprises 1% phenoxyethanol, 10% urea, 10% sodium lactate (60% solution), 1% lactic acid, 1% glycerol, 3% ethylhexylglycerin, 2% polyacrylate crosspolymer-6, 0.5% polyvinylpyrrolidone and 71.5% water by weight. A fire-retardant topical formulation comprising 1% glycerol, 2% polyacrylate crosspolymer-6, 10% sodium lactate solution, 1% phenoxyethanol, 1% lactic acid, 3% ethylhexylglycerin and 0.5% polyvinylpyrrolidone by weight is also disclosed. [Fig: None]

This invention relates to the field of zebrafish model technology, and discloses a method for constructing and applying a chemically induced zebrafish eczema model. The invention constructs a zebrafish eczema model by inducing sensitization and challenge in zebrafish after egg hatching. A two-stage induction method is used to simulate the sensitization and challenge phases of the eczema induction mechanism. Successful model construction is indicated by the repetitive behavioral characteristics observed after both inductions. This invention also reveals that under specific chemical inducer doses, zebrafish exhibit aggregation on the sidewalls of culture dishes and rubbing against the walls, a behavior corresponding to the skin itching symptoms induced by eczema inflammation, which can be directly observed with the naked eye. This model is highly efficient and predictive, and can be used to evaluate the efficacy of drugs, health foods, and other foods in improving eczema.

The application relates to the technical field of antibacterial patches, and particularly discloses an antibacterial slow-release patch, which comprises a skin-friendly and air-permeable layer arranged on the outer side and a slow-release drug layer arranged on the inner side of the skin-friendly and air-permeable layer, a sweat-absorbing substrate layer is arranged on the inner side of the slow-release drug layer, a back adhesive layer is arranged on the rear side of the sweat-absorbing substrate layer, a release paper layer is arranged on the rear side of the back adhesive layer, and a plurality of gel pieces are adhered to the back adhesive layer; the antibacterial slow-release patch is designed in a multilayer structure, can not only resist bacteria and inflammation and efficiently lock water, but also can reduce skin problems caused by sweat accumulation from multiple dimensions. On one hand, bacterial growth is inhibited to avoid inflammation caused by bacterial infection; on the other hand, the skin is kept dry to prevent the horny layer from being excessively hydrated, reduce the occurrence probability of skin diseases such as eczema and miliaria, and provide comprehensive protection for skin health, and the antibacterial slow-release patch is particularly suitable for scenes with more sweat such as sports and high temperature.

L'Oréal Cosmetic Composition Comprising an Endolysin Derived from a Staphylococcus aureus Phage and a Polyhydroxyalkane. The present invention relates to a composition, particularly a cosmetic one, comprising, in a physiologically acceptable medium, at least one endolysin derived from a Staphylococcus aureus phage and at least one polyhydroxyalkane of formula (I). It also relates to the use of such a composition to prevent and / or treat a skin disorder related to colonization by Staphylococcus aureus in an individual in need, and in particular to prevent and / or treat acne and / or eczema in an individual in need, and a non-therapeutic cosmetic process for the care of keratinous materials, particularly of the skin, comprising at least one step of topical application of such a composition to said keratinous materials. Figure for abstract: None

Methods and compositions are provided that enable users to interact with a multimodal digital health platform to assess inflammatory skin conditions, including eczema. Screening for contact allergies is performed with a transdermal adhesive device to deliver contact allergens for epicutaneous patch tests, herein termed a “Contact Allergen Panel”. Automated detection and interpretation may use machine learning based on image feature extraction and integration with allergen skin-sensitizing potency and significance to provide an analysis of reactivity to an allergen of interest.

The invention also refers to a method of inducing, stimulating and / or promoting healing of a wound or a damaged skin area, wherein the method comprises topically treating the skin of a subject surrounding the wound or damaged skin area with conditioned medium derived from cultivation of mesenchymal stem cells of the umbilical cord. Equally, the invention relates to a method of preventing formation and / or recurrence of a wound or a damaged skin area in a subject being at risk of developing a wound or a damaged skin area, wherein the method comprises topically treating the skin of the subject with conditioned medium derived from cultivation of mesenchymal stem cells of the umbilical cord. Further, the invention relates to a method of treating rosacea, psoriasis, eczema, dermatitis, topical steroid withdrawal syndrome, epidermolysis bullosa, or skin damage caused by fragile skin, wherein the method comprises topically treating the skin of a subject surrounding the wound or damaged skin area to be treated with conditioned medium derived from cultivation of mesenchymal stem cells of the umbilical cord. The present invention is also directed to conditioned medium, uses thereof, compositions comprising the same, methods of producing the same as well as uses of these compositions.

The utility model relates to false eyelash patch technical field, concretely relates to a false eyelash with patch structure. It includes fixed strip, and the outside fixed connection of fixed strip is with a plurality of eyelash main parts, and a plurality of eyelash main parts are arrayed along the outside of fixed strip, and the bottom side of fixed strip is provided with first glue layer, third glue layer and second glue layer, and first glue layer and second glue layer are away from each other, and third glue layer is located between first glue layer and second glue layer. The utility model because glue and eyelid are in the state of not ventilating for a long time, can cause the eyelid wet rash of glue and eyelid to appear the situation, through the multiple first circular hole and multiple arc ventilation groove that set up, ensure that false eyelash is in the ventilation state when wearing, and simultaneously on the multiple second circular hole of third glue layer and the multiple third circular hole on third release paper, thereby can improve the efficiency of ventilation, thereby can solve the situation that the long -term wearing false eyelash appears wet rash.

The application discloses a composition with soothing redness and barrier repair functions and application thereof, and relates to the cosmetic field. The composition comprises the following components in mass parts: sea buckthorn fruit extract 0.01-0.1 parts, gardenia flower extract 0.01-1 part, and egg yolk oil 1-5 parts. The composition can be applied to cosmetics. The sea buckthorn fruit extract, the gardenia flower extract and the egg yolk oil are compounded according to a certain mass ratio to be used as effective components of the cosmetics. The composition has the effects of increasing the epidermal water content, soothing redness and repairing the skin barrier. The components of the composition are natural and green, safe, mild and non-irritating, have good smearing and absorption performance, can effectively improve the skin feeling of the skin care product, improve the extensibility of the product after smearing and the softness of the skin after drying, and reduce the sticky feeling of the product. The composition can not only effectively relieve the skin sensitivity and discomfort of adults, but also be used for relieving the problems of infantile eczema, dry and red skin and the like.

This invention belongs to the field of medical materials technology and discloses a medical composite dressing for relieving dermatitis and eczema and its preparation method. First, mussel adhesive protein is dissolved in purified water, and the pH is adjusted to obtain a mussel adhesive protein solution. Trehalose, ectoine, and a portion of glycerin are mixed and dissolved to obtain an active ingredient composite solution. Then, the mussel adhesive protein solution and the active ingredient composite solution are mixed, and the pH is adjusted to obtain phase A. Sodium carboxymethyl cellulose is dissolved in a buffer solution in batches to obtain sodium carboxymethyl cellulose solution A and sodium carboxymethyl cellulose solution B. The two solutions are mixed, and the remaining glycerin and methylparaben are added. After adjusting the pH, phase B is obtained. Finally, phase A is added dropwise to phase B, stirred, and allowed to stand for maturation to obtain the final product. The medical composite dressing provided by this invention has a unique temperature-pH response mechanism, enabling the release of active ingredients such as ectoine and trehalose under weakly acidic conditions, achieving targeted repair and moisturizing of the inflamed area.

The paper diaper with a multifunctional flow guide layer comprises a paper diaper substrate, which comprises a flow guide layer arranged between a core layer and a surface layer, and is composed of a lower layer, a middle support layer and an upper layer arranged in sequence from outside to inside; flow guide holes are uniformly arranged on the flow guide layer, the flow guide holes penetrate the upper and lower surfaces of the flow guide layer to form upper and lower openings, the aperture of the upper opening is larger than that of the lower opening, so that the flow guide holes are tapered holes; flow guide grooves are arranged at the edges of the flow guide layer, and comprise transverse grooves arranged at the front and rear ends of the flow guide layer and longitudinal grooves arranged at the left and right ends of the flow guide layer, the transverse grooves and the longitudinal grooves are connected in sequence to form a flow guide channel. The paper diaper provided by the application can make liquid quickly diffuse through the space gap and quickly infiltrate through the tapered holes, reduce the liquid residue on the surface layer, effectively reduce the back infiltration phenomenon, keep the skin of the wearer dry, and reduce the probability of occurrence of problems such as skin redness and eczema.

Disclosed are compositions and their use for the treatment of human skin, particularly facial skin, to alleviate the symptoms of cosmetic or dermatologic skin conditions. The compositions include black willow bark extract, cats claw extract, and dragon's blood extract. The compositions ameliorate skin conditions including acne, rosacea, blemish, dermatitis, eczema, or the like.

The application relates to the field of skin care products, in particular to a euglena protein extract and application thereof in skin care products. The fine euglena protein extract obtained by the method has a remarkable treatment effect on infant diaper rash and eczema.

The application belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating skin diseases and application thereof. The traditional Chinese medicine composition takes the core principle of 'nourishing kidney and strengthening spleen, and promoting lung and removing dampness' as the core principle, provides a traditional Chinese medicine for treating skin diseases with fast effect, high safety and better curative effect, and provides an optimized scheme for treating atopic dermatitis or eczema for patients with spleen-kidney deficiency, lung depression and dampness accumulation. The kidney-nourishing and spleen-strengthening lung-promoting drink has a significant curative effect on atopic dermatitis, has a better taste, is more easily accepted by children, and has a good application prospect in the market.