198 results about "Treatment acne" patented technology

The invention relates to an application of a stable silicic acid aqueous solution in preparation of a product for treating acne, and the mass concentration of the stable silicic acid aqueous solution is 0.5-2%. The product taking the stable silicic acid aqueous solution as an active ingredient can be used for treating acne or preventing and / or treating sebaceous gland homeostasis imbalance, can fade the color of sebaceous gland spots at the mass concentration of 0.5-2%, and has an anti-acne effect, and meanwhile, the stable silicic acid aqueous solution is low in raw material cost, environment-friendly, safe and suitable for industrial production. The tretinoin can be used as a traditional tretinoin substitute medicine with a good curative effect.

An applicator for treating acne including one or more microneedles, an optical sensor configured to detect acne, a removal system including a suction mechanism configured to remove acne material, and a chamber for containing the acne material, a remedy system configured apply one or more acne remedies, a light source configured to apply a light therapy to skin, and a processor configured to detect acne at one or more affected areas on skin, and direct the applicator to apply treatment, where the treatment includes penetrating the skin at the one or more affected areas with the one or more microneedles, removing acne material with suction mechanism, applying the light therapy to the one or more affected areas, and applying one or more acne remedies to the one or more affected areas.

The invention relates to taurine cross-linked salicylic acid nano-composite gel for efficient transdermal delivery and mild acne removal as well as a preparation method and application of the taurine cross-linked salicylic acid nano-composite gel. The nano-gel comprises salicylic acid, quaternary ammonium salt-73, taurine, polyol, lipid, an emulsifier, a co-emulsifier, an antioxidant and water. Salicylic acid, quaternary ammonium salt-73 and taurine are used as functional components for removing acnes. Salicylic acid can decompose grease on the surface of the skin, so that the oil control effect is achieved, meanwhile, skin metabolism is promoted, angular suppository is loosened, pores are dredged, and acne is treated; quaternary ammonium salt-73 has extremely high antibacterial activity, especially has a remarkable antibacterial effect on propionibacterium acnes causing acnes, and can quickly and thoroughly remove the acnes by being matched with salicylic acid; taurine provides energy required by normal physiological activities of human cells, improves skin immunity, regulates skin water-oil balance and has the effects of improving skin textures, dryness, wrinkles, elasticity, sensitivity and other skin problems, meanwhile, in the using process, taurine is preferentially absorbed by the skin, so that an inclusion shell is broken, and the skin is protected. Rapid release and transdermal absorption of salicylic acid and quaternary ammonium salt-73 are promoted, irritation is reduced, and the three components act synergistically to achieve the functions of mildly, efficiently and rapidly treating acne and reconstructing skin barrier.

The invention provides retinyl sodium hyaluronate and a composition thereof, which are applied to the fields of cosmetics and medicines. The retinoyl sodium hyaluronate is characterized in that all-trans retinoic acid and 13-cis-retinoic acid are esterified with sodium hyaluronate according to a molar ratio of (1.5-3.0): 1, and the esterification degree is 1%-12%; the composition disclosed by the invention is characterized by comprising retinyl sodium hyaluronate and a polyhydric alcohol compound in a mass ratio of 1: (1-10). The sodium retinoyl hyaluronate has a remarkable effect of preventing and treating acne, and the composition is beneficial to improving the stability of the sodium retinoyl hyaluronate and prolonging the validity period of a raw material product of the sodium retinoyl hyaluronate. The retinyl sodium hyaluronate and the composition thereof can be used for preparing cosmetics and medical products for whitening, resisting aging, controlling oil and removing acnes.

The invention belongs to the technical field of skin care products, and particularly relates to a composition for treating acne and a preparation method thereof. The composition comprises the following components: 1-2% of a lactobacillus fermentation product and 5-8% of a plant extract component, the plant extraction component consists of a Pinus densiflora leaf extract, a celery root extract and an aster extract. The mass ratio of the Pinus densiflora leaf extract to the apium graveolens root extract to the aster extract is 1: (1-3): (5-10). Wherein the apium graveolens root extract, the Pinus densiflora leaf extract and the aster extract have a certain synergistic effect in the formula of the composition, so that the composition for treating acne provided by the invention can effectively inhibit the growth of propionibacterium acnes, reduce the occurrence of skin inflammation and effectively treat acne, and has a relatively good market application prospect.

The invention relates to a natural plant composition for treating acne and application thereof. The composition comprises a scutellaria baicalensis extract, a fructus cnidii extract, a herba violae extract, a mangnolia officinalis extract, a Chinese herbaceous peony extract, a radix ophiopogonis extract, a silybum marianum extract and a gastrodia elata extract. The formula is designed according to the traditional Chinese medicine compatibility theory, and the composition formula has a synergistic effect and can effectively inhibit growth of propionibacterium acnes, reduce skin inflammation and generation of erythema and acne marks after acnes, promote fading of the acnes and skin repair and effectively treat the acnes. The composition is stable in formula quality, safe and free of skin irritation, provides a new thought for acne treatment and skin repair, and has a good market application prospect.

The present invention provides a Chinese medicine composition for treating acne, a preparation method and an application thereof, and belongs to the technical field of Chinese medicine. The Chinese medicine composition comprises the following raw materials in parts by weight: 5 to 30 parts of Sophora flavescens, 5 to 30 parts of Salvia miltiorrhiza, 5 to 30 parts of Chrysanthemum indica, 5 to 30 parts of White Peony Root, and 1 to 10 parts of Licorice. The present invention provides a Chinese medicine composition for treating acne, a preparation method and an application thereof, the Chinese medicine composition has a small number of medicinal flavors, 5 selected Chinese medicines are properly compatible, the proportion is reasonable, and it has the effects of oil control, anti-inflammatory and antibacterial. The ingredients are simplified as much as possible while meeting the efficacy of treating acne, and the preparation method is simple, the ingredients are safe and have no toxic side effects, and can be used for a long time. The topical gel prepared by the Chinese medicine composition is accurately applied for 3 days, and the number and volume of acne are significantly reduced, and the product is mild and non-irritating, and has the effects of rapid acne removal and soothing.

The invention belongs to the technical field of medical instruments, and particularly relates to a dermatological acne cleaning device which comprises a shell and a medicine applying frame, the shell is an assembly carrier of the cleaning device, the shell is a vertically-through square shell, and the medicine applying frame is fixedly arranged at a through opening in the bottom face of the shell. Micro through grooves are formed in the medicine applying frame, concave-convex textures are arranged on the surface of the medicine applying frame, and the medicine applying frame is used for applying ointment for treating acne on the skin; the fixing plate is fixedly arranged on the inner wall of the shell; and the sliding frame is mounted on the bottom surface of the fixed plate through a damper. The cleaning roller with the pricking needles is used and matched with the air blowing bag to inflate air into the air inflation bag, so that the multiple sets of pricking needles in the cleaning roller can efficiently prick acne on the skin in the rolling process, meanwhile, the medicine applying frame is used for applying anti-inflammatory and antibacterial ointment in time, infection is effectively prevented, and inflammation recovery is accelerated.

The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine composition for treating acne and a preparation method thereof. The traditional Chinese medicine composition comprises the following components in parts by weight: 270 parts of humifuse euphorbia herb, 90 parts of chinaroot greenbrier, 63 parts of aloe, 45 parts of fructus chebulae, 45 parts of fructus chebulae immaturus, 45 parts of tamarind, 45 parts of ziziphus jujube, 45 parts of polypody yunnanensis and 25 parts of scammonia resina. The traditional Chinese medicine composition provided by the invention has a remarkable inhibition effect on acne inflammatory response induced by propionibacterium acnes.

Provided are methods and compositions suitable for treating acne, disrupting a biofilm, and / or killing bacteria contained in a biofilm. Certain methods comprise contacting skin in need of such treatment with a composition comprising two alpha hydroxy acids and a polyhydroxy acid.

The invention provides a traditional Chinese medicine composition and traditional Chinese medicine granules for treating acne as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compositions. The invention provides a traditional Chinese medicine composition for treating acne. In the traditional Chinese medicine composition, white mulberry root-bark, oldenlandia diffusa and the like are sweet and cold in nature, have the effect of clearing away heat and toxic materials and are monarch drugs; the scutellaria baicalensis, the honeysuckle, the selfheal and the like are cold and cool in nature, are medicines for clearing heat and removing dampness, are matched with the oldenlandia diffusa and the white mulberry root-bark to have a mutual promotion effect, and are ministerial medicines; the rhizoma alismatis is sweet and cold in nature and taste, has the effects of promoting diuresis, excreting dampness, discharging heat and enabling fire to flow out of the bladder, and has a positive and assistant effect; the radix rehmanniae recen, the radix polygonati officinalis, the charred hawthorn and the like have the effects of nourishing yin, moisturizing the lung, strengthening the body resistance and eliminating evil, have a counter-adjuvant effect and are used as assistants and guides; the traditional Chinese medicine composition has the effects of clearing away lung-heat, purging fire and removing dampness. The traditional Chinese medicine composition can be used for treating heat-toxic acne vulgaris and can improve and treat inflammation caused by propionibacterium acnes. And the traditional Chinese medicine composition is convenient to take orally and high in patient compliance, and has a remarkable acne treatment effect.

This invention relates to compositions (e.g. immunogenic compositions) which can be used to immunise against C. acnes. The compositions comprise C. acnes antigens and antigen combinations, used in the form of nucleic acids (e.g. mRNAs) encoding antigenic proteins or in the form of recombinant protein antigens.

The modular led light therapy mask addresses the shortcomings in the prior art by offering a modular LED light therapy mask that enables targeted treatments for various facial areas, with the flexibility to treat the upper face, lower face, or full face depending on the user's requirements. The device's innovative use of conductive magnetic connections to power and control the lower unit sets it apart from existing devices. The modular led light therapy mask for targeted facial treatments provides targeted treatments for various facial areas, including the reduction of wrinkles and fine lines, treatment of acne, lip plumping, and hairline follicle health enhancement. The device uses spectrum-specific LED light therapy to achieve its intended purposes.

The invention relates to application of chenodeoxycholic acid or pharmaceutically acceptable salt thereof in preparation of a medicine for treating acne. The chenodeoxycholic acid disclosed by the invention can be a natural organic compound or a synthetic organic compound, has relatively strong propionibacterium acnes inhibitory activity and a pharmacodynamic effect of resisting lipid secretion, and is used as an active component to be prepared into a pharmaceutical composition for treating acnes together with a pharmaceutically acceptable carrier.

Pharmaceutical compositions comprising a first anti-acne compound, a second anti-acne compound, and an anti-photoaging compound are described. Methods for the treatment of acne and photoaging using the compositions are also described.

The present invention discloses a combined drug for treating acne, which contains bletilla stilbene components and patchouli essential oil for simultaneous or separate administration. By combining bletilla stilbene components and patchouli essential oil in a specific ratio, the present invention significantly inhibits Propionibacterium acnes and acne inflammation, thereby playing a role in treating acne. Moreover, the effect is better than that of either bletilla stilbene components or patchouli essential oil used alone, and is more effective than adapalene gel commonly used at present, showing a synergistic effect and having practical popularization and application value.

The present disclosure provides methods of treating skin acne-like rash in a subject in need thereof. The method comprises applying an effective amount of picosterone-17 alpha-propionate to the surface of the subject. The acne-like rash may include papules, pustules, nodules, scabs, cysts, or any combination thereof on an affected area of the subject. An effective amount of the picosterone-17 [alpha]-propionate can be administered in a surface pharmaceutical formulation comprising the picosterone-17 [alpha]-propionate and one or more pharmaceutically acceptable carriers.

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. The applied substance can include a freezing point depressant and a liposome, an oil-in-water emulsion, a water-in-oil emulsion, or an oil-in-oil emulsion and can be configured to protect or target tissue. The substance and a surface of the skin can be cooled using the applicator to treat acne and other skin conditions.

The present application provides a kind of retinyl hyaluronate sodium and its composition applied in the field of cosmetics and medicine.The retinyl hyaluronate sodium of the present application is characterized by all-trans retinoic acid and 13-cis retinoic acid esterification with sodium hyaluronate in a ratio of 1.5-3.0:1 (molar ratio), and the esterification degree is 1%-12%;The composition of the present application is characterized by retinyl hyaluronate sodium and polyol compound in a ratio of 1:1-10 (mass ratio).The retinyl hyaluronate sodium of the present application has significant effect in preventing and treating acne, and the composition is beneficial to improve the stability of retinyl hyaluronate sodium, prolong the shelf life of retinyl hyaluronate sodium raw material product.The retinyl hyaluronate sodium and its composition of the present application can be used for preparing whitening, anti-aging, oil control and acne-removing cosmetics and medical products.

Cosmetic composition comprising an endolysin derived from a Staphylococcus aureus phage and a mineral filler. The present invention relates to a composition, particularly a cosmetic one, comprising, in a physiologically acceptable medium, at least one endolysin derived from a Staphylococcus aureus phage and at least one mineral filler selected from hydrophilic fumed silicas and spherical porous silica particles. It also relates to the use of such a composition to prevent and / or treat a skin disorder related to colonization by Staphylococcus aureus in an individual in need, and in particular to prevent and / or treat acne and / or eczema in an individual in need, and a non-therapeutic cosmetic process for the care of keratinous materials, particularly skin, comprising at least one step of topical application of such a composition to said keratinous materials.

The present invention relates to topical formulations comprising a combination of antimicrobial peptides (AMP), in particular synthetic cyclic peptide compounds based on thiazolidine and # imgabs0 # oxazolidine components, and a skin soothing substance, such as menthoxypropanediol, a substance that enhances the skin barrier, such as omega-6 fatty acids, and / or a flavonoid, such as licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone, for example licochalcone. In particular, the present invention relates to compounds that synergistically and selectively fight against pathogenic bacteria, such as Staphylococcus aureus (S. aureus) and Propionibacterium acnes (C. acnes), but not fight against skin symbiotic bacteria, such as Staphylococcus epidermidis (S. epidermidis). The formulations can be advantageously used in the treatment of acne or atopic dermatitis, as well as in the care of skin that has been impaired by acne or atopic dermatitis.

The present application relates to regimens, methods of treatment, and compositions for treating acne in a subject suffering from acne.

The present invention discloses the use of garlic extracellular vesicles in the preparation of a drug for treating acne. Fresh Yunnan purple-skinned garlic cloves are peeled, the rhizomes removed, and then washed and juiced. The squeezed garlic juice is subjected to ultracentrifugation. The resulting solution is subjected to sucrose gradient purification. The resulting solution is mixed and packaged to obtain garlic extracellular vesicles. The extracted garlic extracellular vesicles are applied to acne as an experimental acne treatment drug. Retinoic acid cream is used as a positive control group, and normal saline is used as a model group. The therapeutic effect of garlic extracellular vesicles on acne healing in rats is observed. The results show that garlic extracellular vesicles can effectively increase the reduction rate of acne thickness, significantly increase the reduction rate of acne area, significantly increase the smoothness and flatness of skin healing, and significantly shorten the acne healing period.

The invention relates to oil-controlling and acne-removing salicylic acid cleansing oil and a preparation method thereof. The oil-controlling and acne-removing salicylic acid cleansing oil is prepared from the following components in parts by weight: 75 to 95 parts of grease, 0.1 to 2 parts of salicylic acid, 0.1 to 1 part of polyglycerol-10 laurate, 1 to 30 parts of emulsifier and 0.1 to 5 parts of water. Salicylic acid and polyglycerol-10 laurate in the cleansing oil are matched for use, so that the cleansing oil not only can achieve the effects of resisting inflammation, resisting bacteria and regulating cutin of a human body, but also has very strong fat solubility, can penetrate into the deepest hair follicle part of a patient, improves the condition of pore blockage, achieves the effect of effectively treating acne, and is free of toxic and side effects. By adding the salicylic acid, the polyglycerol-10 laurate, the grease, the emulsifier and the like, the cleansing oil not only can have a good effect of removing cosmetics, but also can have the effects of controlling oil and removing acnes.

The invention relates to a composition comprising shikimic acid and an extract of Prunus Mume, and its non-medical and medical use, in particular for use in the treatment of acne.

The present invention relates to an aqueous extract obtained from a plant of the genus Aster for cosmetic or therapeutic applications, in particular in the prevention and / or treatment of acne.

The invention provides a toad skin extract, a traditional Chinese medicine composition, a traditional Chinese medicine gel ointment, a preparation method and application, and belongs to the technical field of traditional Chinese medicine extraction and traditional Chinese medicine preparations. The preparation method of the toad skin extract comprises the following steps: mixing dried toad skin with an ethanol solution, performing reflux extraction to obtain a toad skin extracting solution, performing centrifugation to obtain supernate, and performing concentration and drying to obtain the toad skin extract. According to the preparation method, the content of bufalin, cinobufagin, resibufogenin and indole alkaloid extracted from the toad skin is increased, the preparation method is stable and feasible, and the prepared toad skin extract can inhibit bacteria. The traditional Chinese medicine gel ointment is easy to coat, smooth and bright in ointment body, good in skin following performance and uncovering and pasting performance, free of residues in stripping, good in adhesiveness, excellent in overall quality and good in reproducibility, has the effects of diminishing swelling and treating acne, is free of acute toxicity, does not cause the conditions of skin erythema and edema, is free of irritation to skin and is high in safety.

The present disclosure belongs to the field of pharmaceutical formulations and particularly relates to a composition with a synergistic therapeutic effect on acne lesions and a preparation method therefor and use thereof. The composition provided by the present disclosure comprises active ingredients adapalene and dapsone, which exhibit a synergistic therapeutic effect on inflammatory acne lesions when used in combination. Compared with corresponding single drugs, the composition can significantly reduce the number of inflammatory lesions; meanwhile, relative to the topical use of adapalene alone, the composition of the present disclosure can mitigate skin irritation reactions caused by adapalene and exhibits good safety.

The invention provides a local external medicine composition for treating acne as well as a preparation method and application of the local external medicine composition. The pharmaceutical composition disclosed by the invention is prepared from ozlafloxacin, adapalene, a solubilizer, a surfactant and a solvent, wherein the solubilizer is an alcohol compound and / or an ester compound, the hydrophilic-lipophilic balance value of the surfactant is 20-30, and the pH value of the pharmaceutical composition is 4s < 10 >. According to the pharmaceutical composition disclosed by the invention, the ozlafloxacin and adapalene can be effectively released, and in a stability experiment, the content of the ozlafloxacin and adapalene can be kept stable, obvious degradation does not occur, and the particle size distribution is not obviously changed.