246 results about "Photoaging" patented technology

A skin care composition is provided which preferably comprises a mixture of N-acetylcysteine and L-carnosine in combination with a cosmetic, dermatological or pharmaceutically acceptable carrier therefor. The composition may optionally be provided as a sunscreen formulation, and provides a method for the prevention, amelioration or treatment of pathological conditions of the skin, including, but not limited to, intrinsic or chronological aging, or aging due to sun damage (photoaging), and which conditions are caused by, or exacerbated by, oxidative stress, carbonyl stress, or a combination of both.

The invention provides a nanometer composite modifier used for improving the weatherability of a powder dye. The nanometer composite modifier consists of a flatting agent, inorganic nanometer powder, an organic anti-aging addition agent and a powder dope basic resin. The nanometer composite modifier fully exerts the collaborative anti-aging effect of the organic anti-aging addition agent and the inorganic nanometer powder as well as improves the problem that the flatting agent is over-added which is easy to float on the surface of a paint film. The invention also provides a preparation method of the modifier. The method is simple in technique and low in cost. The master batches of the modifier can be used in the powder dope to improve the property for resisting the aging of ultraviolet light of the powder dope to a great extent; the flatting property of the paint film of the powder dope is also improved.

A pharmaceutical composition for treatment of skin aging including a pharmaceutically effective amount of estriol; a pharmaceutically effective amount of estradiol; a pharmaceutically effective amount of hyaluronic acid; a pharmaceutically effective amount of green tea extract; and a pharmaceutically acceptable carrier is provided. In some embodiments, the composition further includes ascorbic acid, date palm extract, or a combination thereof. Also disclosed is a method for treating symptoms of skin aging and photoaging by administering a pharmaceutical composition having estriol, estradiol, hyaluronic acid, green tea extract, a pharmaceutically acceptable carrier and optionally, ascorbic acid and date palm extract. A method of promoting urogenital function is likewise provided wherein a pharmaceutical composition having estriol, estradiol, hyaluronic acid, and green tea extract is applied intravaginally.

The invention provides a novel anti-skidding coating for a deck, which is composed of the following components in parts by weight: 30-45 parts of latex, 2-5 parts of film forming accessory ingredient, 15-25 parts of titanium pigment, 5-20 parts of filler, 0.2-1.0 part of wetting dispersant, 5-15 parts of anti-skidding agent, 0.1-0.5 part of de-foaming agent, 0.5-1.0 part of age inhibitor, 0.5-2.0 parts of thickening agent, 0.5-1.0 part of anti-mildew corrosion-protection agent, and 10-25 parts of water. The coating of the invention has very high wearing resistance and anti-skidding degree; the formed coat has good adhesive ability, wearing resistance, weather resistance, light-proof aging resistance, seawater resistance and salt mist resistance, wherein the artificial weathering aging test (ultraviolet UVB-313 resistance) is 4000 h, and the wearing resistance (1000g/1000r) is not more than 30mg; the coating is applied to the corrosion prevention of the decks and the iron surfaces of the sea apparatus of boats and ocean platforms, wherein the decks and the iron surfaces require to have weather resistance, anti-skidding property, wearing resistance, and seawater corrosion resistance. The preparation method of the anti-skidding coating for the deck is simple in technology, low in cost and is performed without special apparatus.

Methods of treatment or prevention of hyperproliferative diseases or pre-cancerous conditions affecting epithelial cells, such as psoriasis, vitiligo, atopic dermatitis, or hyperproliferative or UV-responsive dermatoses, hyperproliferative or allergically mediated diseases of other epithelia and methods for reducing photoaging, or oxidative stress or for prophylaxis against or reduction in the likelihood of the development of skin cancer, are disclosed.

The invention provides a skin barrier repairing complex, facial cream and a preparation method therefor. The skin barrier repairing complex comprises a composition for repairing skin barrier, hydroxylasiaticoside, deacidified carnosine, a glycyrrhiza inflata root extract, a radix scutellariae extract and a hamamelis extract, wherein the composition for repairing skin barrier comprises sea fennelcallus culture filtrate, Ectoin and a hydrolyzed red alga extract. The skin barrier repairing complex can achieve triple effects of simultaneously repairing cutin barrier, repairing immunologic barrier and strengthening microbiologic barrier; and the facial cream prepared from the skin barrier repairing complex is obvious in repairing effect and can be used for effectively improving hydrature of skin, increasing the content of hyaluronic acid in the skin, improving photoaging, helping cell saccharification reversing and reducing fine grain area.

Human and mammalian skin undergoes a variety of changes associated with chronological aging. Various environmental factors, disease states and genetic disorders may accelerate both the appearance of aging skin and also the structural and functional changes associated with aging skin. Ultraviolet radiation from the sun is one of the classic known and well-defined means of accelerating or worsening the aging of the skin and this is frequently termed photoaging. Other environmental factors, such as oxidative stress, free radicals, environmental toxins such as ozone and cultural customs or habits such as tobacco smoking are other known probe accelerators in photo aging skin. A wide variety of other factors known and unknown contribute to accelerated or premature aging of the skin. This invention discusses methods where electromagnetic radiation, in particular, light, can be used to photobiomodulate the activity of living cells to delay, diminish, retard or even reverse the structural and functional effects of aging of the skin and other living cells and tissues. In particular methods described for improving the appearance, structure, function of aging skin, including up and down regulating the genotypic markers for the phenotype of aging skin.

The present invention relates generally to the use of vitamin B12 (cobalamin or cyanocobalamin) alone or in combination with other photoprotective agents, including specifically other vitamins such as vitamin B9 (folic acid or folate) and vitamin B3 (niacin or niacinamide), or any chemical derivative of these vitamins and their salts, as a filter to protect cells against the damaging effects of ultraviolet (UV) light. The invention is, in one aspect, a method of reducing the rate of UV damage to cells exposed to a UV light source, by treating the cells with the vitamin composition, either alone or in combination with other photoprotective agents. Other aspects of the invention are compositions comprising effective amounts of vitamin B12 alone or in combination with other photoprotective agents including vitamin B9 and vitamin B3 and a pharmaceutically-acceptable carrier, that are useful in protecting cells, particularly skin cells, against the burning, genotoxic (mutagenic and carcinogenic), immunosuppressive and photoaging effects of UV light, especially sunlight. The invention has application as a UV light filter in oral preparations including tablets and drinks, topical creams, lotions, sprays, wipes and cosmetics. The invention also has application as a medicinal treatment for dermatological conditions caused by exposure to sunlight, such as actinic keratoses, photodermatitis, photo-induced (discoid) lupus erythematosus and the photosensitizing effects of a variety of drugs used commonly in clinical practice (e.g. certain antihistamines, ACE inhibitors, and antibiotics such as tetracycline).

The present invention relates to a cosmetic, dietary supplement, or pharmaceutical composition for oral ingestion or topical application to the skin comprising effective amounts of a tocopherol quinone, tocopherol quinol, plastoquinol, menaquinol, or phylloquinol compound, or any combination thereof as a method for preventing free radical oxidation or preventing or treating environmental skin damage including photoaging, trauma, discoloration, dryness, thickness, elasticity, or wrinkles.

There is provided a screening method which can select a photoaging-preventing or improving agent or a wrinkle-preventing or improving agent with efficiency and reliability. The screening method for a photoaging- or wrinkle-preventing or improving agent selects, as a candidate, a substance inhibiting the expression of keratin 6 and/or keratin 16 genes or keratin 6 and/or keratin 16 proteins in a skin tissue or cell.

The invention relates to a light aging resistant photodiffusion polycarbonate composite material and a preparation method thereof. The composite material is prepared from the following raw materials in parts by weight: 700-900 parts of polycarbonate aggregate, 100-300 parts of polycarbonate powder, 0.5-5 parts of photodiffusion agent, 2-8 parts of light stabilizer, 1-5 parts of antioxidant and 0.5-2 parts of processing agent. The light aging resistant photodiffusion polycarbonate composite material is prepared from the raw materials in high-speed mixing, extruding and pelletizing manners. The light aging resistant photodiffusion polycarbonate composite material disclosed by the invention has the advantages of being good in processing formability, good in light aging resisting performance, good in light transmittance and haze, and the like.

A composition comprising cartilage extract, grape seed extract and tomato extract was found to have remarkable anti-oxidant effect and free-radical inhibition. The tomato extract comprises lycopene. The composition which comprises a hydrophilic antioxidant, a lipophilic (hydrophobic) antioxidant, and a cartilage extract dramatically increases collagen synthesis in the dermis. Furthermore, the composition lowers collagenase activity and levels of advanced glycation end products (AGE). The signs of ageing, such as photoageing due to exposure to UV radiation, are related to the levels of collagen syntheses and free-radical oxidation. Compositions of the invention are intended for the treatment of ageing skin and the delaying of the onset of the signs of ageing in healthy skin.

The invention relates to a cosmetic composition in the technical field of daily chemical products, in particular to an anti-blue-light cosmetic composition and a preparation method thereof. The composition is mainly prepared from, by mass, 0.1-8 parts of a citrus extract, 0.1-4 parts of a lespedeza capitata leaf/stem extract, 0.1-4 parts of cerium oxide, 0.1-8 parts of a buddleja officinalis extract, 0.1-10 parts of a hedychium coronarium root extract and 0.1-8 parts of a rutin compound. The anti-blue-light cosmetic composition can brighten the skin, reduce the oxidative damage to the skin caused by blue light, increase the survival quantity of epidermal keratinocytes under the UV radiation, maintain the integrity of the skin function, reduce the chronic mild inflammation of light aging, and provide a skin protection effect by reducing free radicals produced by the induced oxidative stress, so that the generation amount of active oxygen ROS declines to improve local microcirculation and play a vasoconstriction role, thereby controlling the fatigue signs caused by direct blue light irradiation, keeping the skin in balance of circadian rhythms, and keeping the skin in a health status.

The invention relates to an ultraviolet aging test method for an asphalt material (including asphalt, asphalt mortar and an asphalt mixture) in a tension state. The ultraviolet aging test method comprises the following steps: selecting a light source for an ultraviolet aging simulation test, and determining the change of the irradiation intensity of the light source along with space and time; preparing samples of the asphalt material; carrying out an ultraviolet aging test on the asphalt material in the tension state, carrying out a subsequent performance test, and analyzing test results. By implementing the test method provided by the invention, a light aging process of an asphalt pavement under a traffic load and ultraviolet light irradiation can be well simulated; an ultraviolet light aging degree of the asphalt material can be comprehensively analyzed; the light aging rules of the asphalt material can be revealed. The test method is reasonable in design, and is detailed and specific.

Described are methods for treating hyperproliferative disorders, including cancers, by administering to the affected mammal (e.g., human) an effective amount of a composition comprising one or more oligonucleotides which share at least 33% but less than 100% nucleotide sequence identity with the human telomere overhang repeat. Methods of treatment or prevention of hyperproliferative diseases or pre-cancerous conditions affecting epithelial cells, such as psoriasis, atopic dermatitis, or hyperprolferative diseases of other epithelia and methods for reducing photoaging, or oxidative stress or for prophylaxis against or reduction in the likelihood of the development of skin cancer, are also disclosed. The compositions and methods are also useful to treating other cancers.