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184 results about "Photoaging" patented technology

Photoaging or photoageing (also known as "dermatoheliosis") is a term used for the characteristic changes to skin induced by chronic UVA and UVB exposure. The deterioration of biological functions and ability to manage metabolic stress is one of the major consequences of the aging process. Aging is a complex, progressive process that leads to functional and aesthetic changes in the skin. This process can result from both intrinsic (i.e., genetically determined) as well as extrinsic processes (i.e., environmental factors). Photoaging is attributed to continuous, long-term exposure to ultraviolet (UV) radiation of approximately 300–400 nm, either natural or synthetic, on an intrinsically aged skin.

Photo-thermal aging resistant polyester composite material and preparation method thereof

InactiveCN119431756AIncrease the number of crosslinksImprove aging resistanceThermal ageingPolymer science
The invention discloses a photo-thermal aging resistant polyester composite material and a preparation method thereof, a modified monomer, a modified filler, benzophenone, terephthalic acid and neopentyl glycol are subjected to esterification condensation polymerization to prepare the composite material, and the modified monomer is added, so that the prepared polyester molecule is of a branched structure; the side chain of a polyester molecule and the surface of the modified filler both contain unsaturated double bonds which can react after being irradiated by ultraviolet light, so that the number of crosslinking points of the composite material is increased, the crosslinking density is further improved, and the anti-aging effect of the material is further improved; the modified filler can improve the high-temperature-resistant effect of the composite material, the modified filler is matched with the hindered phenol structure of the side chain to further improve the heat aging-resistant effect of the composite material, hydroxyl and ketone groups on the modified filler form intramolecular hydrogen bonds, light energy can be converted into heat energy to be released, and then the light aging-resistant effect of the composite material is improved.
Owner:JIANGXI PLASTIC HIGH-TECH MATERIALS CO LTD

Antibacterial PP material and preparation method thereof

InactiveCN119264554Aaccelerated deathExtended service lifeCarbon layerActive agent
The invention relates to an antibacterial PP material and a preparation method thereof, and belongs to the technical field of high polymer materials. The antibacterial PP material is prepared from the following components in parts by weight: 60 to 80 parts of PP resin, 2 to 4 parts of a surfactant, 0.5 to 1.5 parts of a modified antibacterial agent, 0.5 to 1.5 parts of a flame retardant and 0.2 to 0.8 part of an antioxidant, titanium ions in the modified antibacterial agent destroy bacterial cell walls, quaternized intermediate products react with proteins of cell membranes to accelerate bacterial death, and in addition, phenolic hydroxyl groups absorb ultraviolet rays with different wavelengths to inhibit the light aging process; a compact and continuous carbon layer is formed during combustion of the flame retardant and cooperates with phosphorus-oxygen double bonds and melamine, the flame retardant efficiency is improved, aluminum hydroxide coats the surface, hydroxyl is subjected to heat absorption decomposition during combustion, the surface temperature of combustible materials is stabilized, meanwhile, an inert aluminum oxide layer is formed, and the flammability is reduced. The antibacterial PP material prepared by the invention not only has good antibacterial and anti-aging effects, but also has excellent flame retardant property.
Owner:DONGGUAN AURORA BIOTECHNOLOGY CO LTD

Composition with longevity gene activation effect

The invention belongs to the field of daily chemicals, and provides a composition with a longevity gene activation effect, a product containing the composition and application of the composition, and the composition provided by the invention comprises hexapeptide, chlamydomonas and cornflower extract. The hexapeptide, the chlamydomonas nivalis and the cornflower extract are compounded for use, so that the expression of longevity genes KLOTHO and SIRT1 can be remarkably improved. Once the longevity gene serving as the upstream of a signal regulation pathway is activated, various downstream signal pathways can be regulated, such as inhibition of expression of inflammation-related genes, promotion of DNA repair, telomere homeostasis, gene expression of mitochondrial energy and the like, promotion of synthesis of collagen and the like, and finally, longevity of cells and improvement of skin phenotypes are promoted. The effects of resisting wrinkles, tightening and the like are achieved. Therefore, the composition provided by the invention can activate long-life gene expression and regulate and control multiple signal pathways, has potential effects of improving light aging, tightening and resisting wrinkles and the like, and is an anti-aging composition with great potential.
Owner:GUANGZHOU JIYAN COSMETICS TECH CO LTD

4 apos; application of-methylamine baicalein in preparation of anti-photoaging product

The invention discloses an application of 4 '-methylamine baicalein in preparation of an anti-photoaging product. Experimental results show that the 4 '-methylamine baicalein not only has very low toxicity to fibroblasts, but also can remarkably improve the multiplication capacity of the fibroblasts irradiated by the UVB and can remarkably inhibit senescence of the fibroblasts irradiated by the UVB, and the effect of the 4'-methylamine baicalein is remarkably superior to that of baicalein; therefore, at least one of 4 '-methylamine baicalein or pharmaceutically acceptable salts, tautomers, stereoisomers and precursor compounds thereof can be used as an active ingredient for preparing anti-photoaging products, and the compound has important significance and application value especially for solving the photoaging problem generated by UVB phototherapy.
Owner:HANGZHOU THIRD PEOPLES HOSPITAL (HANGZHOU HUIMIN HOSPITAL HANGZHOU THIRD AFFILIATED HOSPITAL OF ZHEJIANG UNIV OF TRADITIONAL CHINESE MEDICINE) +2

Medical beauty treatment device with LED light source and body beauty treatment system based on phototherapy

The invention belongs to the technical field of optical beauty, and discloses a medical beauty device with an LED light source and a body beauty system based on phototherapy, and the method comprises the steps: collecting multi-source data for fusion, and generating a skin health map through an ICP registration algorithm; based on the skin health map, segmenting a high-tolerance area and a blood vessel dense area; distributing laser wavelength, energy density and cooling parameters for each area; the dynamic thresholds are adjusted in real time in a self-adaptive mode through the dynamic thresholds; determining and dividing risk grades through multi-parameter fusion, triggering a grading response mechanism, and generating dynamic energy configuration parameters and a safety control strategy; based on the three-dimensional point cloud coordinates and spatial constraint conditions, dynamically adjusting laser path planning through a path re-planning algorithm, and generating a phototherapy execution log; generating a curative effect evaluation report based on the phototherapy execution log, and constructing a photoaging risk map; and updating the energy rule base through a reinforcement learning algorithm, and determining parameters of a threshold value and a weight coefficient of a registration algorithm to form closed-loop optimization.
Owner:YLIN ELECTRONICS CO LTD

Application of plant-derived extracellular vesicles in preparation of product for preventing and treating photoaging and topical application composition

The invention discloses application of plant-derived extracellular vesicles in preparation of a product for preventing and treating photoaging and a topical application composition. Pseudo-ginseng is used as a raw material for extraction and purification of plant-derived extracellular vesicles, and results show that the pseudo-ginseng-derived extracellular vesicles can significantly treat or improve photoaging. The invention explores the practical application of the fresh pseudo-ginseng extracellular vesicles based on the traditional theory of traditional Chinese medicine, and clarifies the molecular mechanism of the pseudo-ginseng extracellular vesicles. In a word, the extracellular vesicles derived from pseudo-ginseng have a wide application prospect in treatment of skin aging.
Owner:GUANGDONG MODERN HANFANG TECH CO LTD

Anti-radiation fabric and preparation method thereof

The invention discloses an anti-radiation fabric and a preparation method thereof, and relates to the technical field of fabric preparation. When the anti-radiation fabric is prepared, bismuth powder is pre-modified with (3-chloropropyl) trimethoxysilane and then reacts with an anti-aging agent to prepare modified bismuth powder; the preparation method comprises the following steps: enabling 4-aminophenylethanol and 4-(2-ethoxyl) benzaldehyde to react to prepare a flame-retardant monomer, and then enabling the flame-retardant monomer to react with isophorone diisocyanate and 1, 4-butylene glycol to prepare polyurethane; the preparation method comprises the following steps: reacting dimethylallylamine with 1, 3-bis (chloromethyl)-1, 1, 3, 3-tetramethyldisiloxane to obtain an antibacterial cross-linking agent; the modified bismuth powder, N, N-dimethylformamide, polyurethane, an antibacterial cross-linking agent and benzoyl peroxide are mixed to prepare a polyurethane coating, the outer side surface of polyester base cloth is coated with the polyurethane coating, drying is conducted, and the anti-radiation coating fabric is prepared. The anti-radiation fabric prepared by the invention has good anti-radiation, anti-light aging, flame-retardant and antibacterial properties.
Owner:南通科晟纺织有限公司

Drug-loaded polygonatum kingianum extracellular vesicles, preparation method and application of drug-loaded polygonatum kingianum extracellular vesicles in preparation of anti-photoaging products

The invention discloses a drug-loaded polygonatum kingianum extracellular vesicle, a preparation method and an application of the drug-loaded polygonatum kingianum extracellular vesicle in preparation of an anti-photoaging product, and aims to provide a drug-loaded polygonatum kingianum extracellular vesicle which has relatively high encapsulation efficiency and drug loading rate and good stability and biocompatibility, can effectively treat skin UVB inflammation, solves the problem that a drug is insoluble in water, improves the curative effect, and can be used for preparing an anti-photoaging product and a preparation method of the drug-loaded polygonatum kingianum extracellular vesicle. According to the technical scheme, the drug-loaded polygonatum kingianum extracellular vesicles comprise the polygonatum kingianum extracellular vesicles and drug active components loaded in the polygonatum kingianum extracellular vesicles, and the drug-loaded polygonatum kingianum extracellular vesicles comprise the drug-loaded polygonatum kingianum extracellular vesicles and the drug active components loaded in the drug-loaded polygonatum kingianum extracellular vesicles. The pharmaceutical active component is at least one of resveratrol, glutathione, astaxanthin and vitamin C. The invention further discloses a preparation method of the pharmaceutical composition. The invention belongs to the technical field of biological medicine.
Owner:GUANGDONG UNIV OF TECH

Composition of cyclic peptide and recombinant collagen as well as preparation method and application of composition

The invention discloses a cyclic peptide composition, a preparation method thereof and application of the cyclic peptide composition in preparation of medical products and / or cosmetics. The cyclic peptide composition comprises a cyclic peptide and 21-type collagen, wherein the amino acid sequence of the cyclic peptide is as shown in SEQ ID NO. 1; the amino acid sequence of the type 21 collagen is as shown in SEQ ID NO. 2. The cyclopeptide composition disclosed by the invention is used for preparing medical products and / or cosmetics for resisting light aging and resisting aging, especially light aging, and the cyclopeptide and the type 21 collagen have a synergistic effect, so that an unexpected synergistic effect is achieved.
Owner:BETTER WAY (SHANGHAI) COSMETICS CO LTD

Polyvinyl chloride plastic material and preparation method thereof

The invention discloses a polyvinyl chloride plastic material and a preparation method thereof, and the polyvinyl chloride plastic material comprises the following components by weight: 100 parts of a polyvinyl chloride matrix; 5 to 10 parts of light response type nano particles with # imgabs 0 # as a core and # imgabs 1 # as a shell; 2-8 parts of a halogen ion carrier type mesoporous material; 1-5 parts of a halogen free radical trapping agent; and 1-3 parts of a layered barrier material. According to the technical scheme, the technical problems that in the prior art, a polyvinyl chloride material is prone to light aging in a marine environment, and micro-plastic pollution is generated are solved.
Owner:ANGREEN DONGGUAN NEW MATERIALS TECH

Antibacterial waterborne polyurethane-chitosan compound as well as preparation method and coating thereof

The invention relates to the technical field of polyurethane coatings, and discloses an antibacterial waterborne polyurethane-chitosan compound, a preparation method thereof and a coating, the antibacterial waterborne polyurethane-chitosan compound comprises the following raw material components: chitosan, oligomeric polyol, diisocyanate, a chain extender, a cross-linking agent, a neutralizer, a catalyst and a modified compound, the modified compound comprises graphene oxide, nano titanium oxide, a sensitizing agent and a dispersing agent. In the technical scheme provided by the invention, the nano titanium oxide can play a role in coordination crosslinking among molecular chains and play a synergistic role with the dispersing agent, so that the dispersion uniformity of the modified compound in polyurethane is improved, and meanwhile, the nano titanium oxide can be used as a catalyst for photocatalytic oxidation reaction to oxidize bacteria and fungi, so that the antibacterial effect is realized; by adopting the sensitizer, the applicable light wavelength range when the nano titanium oxide plays a catalytic function can be expanded, the light aging effect of light on the polyurethane material is reduced, and the antibacterial effect of polyurethane is improved.
Owner:HUIZHOU QIANLANG CHEM CO LTD

Multi-dimensional comprehensive detection system for anti-aging effect of skin care product

The invention discloses a skin care product anti-aging effect multi-dimensional comprehensive detection system, which comprises an in-vitro cell model experiment module for detecting indexes such as cell activity, proliferation, migration, apoptosis and antioxidant enzyme activity by simulating natural aging and light aging conditions; the content change of skin structure components such as collagen, elastic fibers and laminin is quantitatively analyzed, the DNA damage repair capacity is reflected by measuring the expression quantity of gammaH2AX, epigenetics research is developed, and the methylation state change of a CpG island is monitored; and the tissue engineering and three-dimensional skin model experiment module is used for performing morphological observation, biochemical index detection and skin physiological parameter evaluation under the condition of simulating a real skin environment by utilizing an artificial skin model. The whole process from the in-vitro cell model to the clinical human body test is covered, and the actual efficiency of the skin care product for delaying or improving the skin aging process can be accurately and objectively evaluated through multi-angle and multi-level data integration analysis.
Owner:DA JIANG (TIAN JIN) SHENG WU ZHI YAO YOU XIAN GONG SI

Peptide having Anti-aging activity, and use thereof

The present invention relates to a peptide having anti-aging activity and a composition for skin regeneration or suppressing skin aging, comprising the peptide as an active ingredient. The peptide according to the present invention, comprising an amino acid sequence of SEQ ID NO: 1, has anti-aging activity and thus can be used as a raw material for a cosmetic product for skin regeneration or suppressing skin aging or as a raw material for a pharmaceutical product for preventing, ameliorating, or treating photoaging.
Owner:CAREGEN

Environment-friendly efficient cosmetic hose and preparation method thereof

The invention discloses an environment-friendly efficient cosmetic hose and a preparation method thereof.The cosmetic hose is prepared from, by weight, 60-80 parts of low-density polyethylene, 9-15 parts of high-density polyethylene, 15-20 parts of metallocene polyethylene, 30-40 parts of a PCR regenerated material, 1-3 parts of an antioxidant, 5-10 parts of a plasticizer, 1-3 parts of a coupling agent and 2-5 parts of a graphene auxiliary. The cosmetic hose is prepared by reasonably proportioning the raw materials, mixing and melting the raw materials at high temperature, extruding the raw materials into a hose shape, and then cooling, shaping, cutting, polishing and packaging the hose. Compared with the prior art, the prepared environment-friendly efficient cosmetic hose has excellent environment-friendly performance and also has excellent barrier property, tensile strength, antibacterial property and ultraviolet aging resistance, long-term use stability of the cosmetic hose is facilitated, and good quality control is guaranteed in the storage process of packaged contents.
Owner:GUANG DONG QIAO LEI BAO ZHUANG KE JI YOU XIAN GONG SI

Peptide having Anti-aging activity, and use thereof

The present invention relates to a peptide having anti-aging activity and a composition for skin regeneration or suppressing skin aging, comprising the peptide as an active ingredient. The peptide according to the present invention, comprising an amino acid sequence of SEQ ID NO: 1, has anti-aging activity and thus can be used as a raw material for a cosmetic product for skin regeneration or suppressing skin aging or as a raw material for a pharmaceutical product for preventing, ameliorating, or treating photoaging.
Owner:CAREGEN

Anti-migration light-conversion adhesive film and preparation method thereof, and photovoltaic module

The present invention relates to the technical field of photovoltaic encapsulation films, and discloses an anti-migration light-conversion film and a preparation method thereof, and a photovoltaic module. The raw materials of the anti-migration light-conversion film include a base resin, a light-conversion compound, and an initiator; the light-conversion compound includes: an organic light-conversion agent, a polymethyl methacrylate layer coated on the outside of the organic light-conversion agent, an epoxy silane coupling agent grafted on the outside of the polymethyl methacrylate layer through an epoxy ring-opening reaction, and an alkenyl silane coupling agent grafted on the epoxy silane coupling agent through a silaneoxy hydrolysis condensation reaction. The light-conversion film of the present invention adopts a special light-conversion compound. After being made into a film together with the base resin and the initiator, it can slow down the migration of the light-conversion agent to a large extent without affecting the light transmittance of the film, thereby improving the anti-ultraviolet light aging performance of the photovoltaic module and slowing down its power attenuation under ultraviolet light.
Owner:ZHEJIANG XIANGBANG YONGSHENG NEW ENERGY CO LTD

Method for evaluating in-vitro anti-saccharification effect and application thereof

The invention provides an in-vitro anti-saccharification effect evaluation method and application thereof, and belongs to the technical field of skin saccharification resistance. A photoaging fibroblast model is adopted, after induction of an inducer, anti-saccharification evaluation is carried out by detecting the contents of collagen and waveform protein after application of a substance to be detected, and it is proved that the anti-saccharification effect of the anti-saccharification substance in the cell model is consistent with the result in human body effect evaluation; the evaluation method can be applied to screening and evaluation of anti-skin saccharification substances.
Owner:SHANGHAI JAKA BIOTECH CO LTD

Automatic ultraviolet irradiation device for cell photoaging model

The utility model relates to an automatic ultraviolet irradiation device for a cell photoaging model. The automatic ultraviolet irradiation device comprises a box body and a cabinet door hinged to the front surface of the box body, the ultraviolet irradiation mechanism is mounted in the box body; the controller is mounted on the front surface of the box body; the ultraviolet irradiation mechanism comprises rotating rods rotationally installed on the two sides of the inner wall of the box body, a driving motor is started to drive the rotating rods to rotate, the rotating rods drive discs to rotate, a plurality of lamp tubes between the two discs rotate, the damaged lamp tubes are rotated to the upper portion, the normally-used lamp tubes are located at the lower portion, and meanwhile the driving motor is started to drive the rotating rods to rotate. The two driving motors are synchronous motors and drive the driving gears to rotate, the surfaces of the driving gears are meshed with the rack parts, the protection plate is pushed to be located between the two discs, used lamp tubes are located below the protection plate, other unused lamp tubes are located above the protection plate, and the unused lamp tubes are protected.
Owner:GUANGZHOU ZHONGKE INSPECTION TECH TESTING CO LTD +1

PET (Polyethylene Terephthalate) titanium sodium film for high-end wallboard and intelligent preparation method of PET titanium sodium film

The invention discloses a PET titanium sodium film for a high-end wallboard and an intelligent preparation method of the PET titanium sodium film. The PET titanium sodium film for the high-end wallboard comprises the following components in parts by weight: 40-60 parts of PET powder, 15-20 parts of NaTi2 (PO4) 3, 0.8-1.6 parts of glycerol and 2-6 parts of a processing aid. Wherein the processing aid comprises 40%-60% of an anti-aging agent and 40%-60% of a flame retardant; the invention relates to the technical field of PET titanium sodium film preparation. According to the PET titanium sodium film for the high-end wallboard and the intelligent preparation method of the PET titanium sodium film, NaTi2 (PO4) 3 is added, so that the prepared PET film has a certain anti-ultraviolet function and relatively good mechanical properties, an ultraviolet shielding effect is achieved, the mechanical properties of the PET film can still be kept good after ultraviolet aging, and the service life of the PET film is prolonged.
Owner:YANGZHOU ZHONGHE TONGSHENG PACKING MATERIAL CO LTD

Recombinant humanized collagen bionic microneedle for skin aging resistance and preparation method thereof

The invention relates to a recombinant humanized collagen bionic microneedle for skin aging resistance, the microneedle comprises a needle tip, a base and a concave chamber, recombinant humanized collagen is loaded on the needle tip, the base and the concave chamber are made of hyaluronic acid, and the recombinant humanized collagen is uniformly distributed on the needle tip of the microneedle. Compared with a traditional smearing method and a conical microneedle, the bionic microneedle has a better anti-aging effect in a photoaging mouse model. The penetration depth of the micro-needle is obviously improved, and the solubility and the adhesiveness of the micro-needle are superior to those of the existing collagen micro-needle.
Owner:HARBIN INST OF TECH

Sugar derivative of hydroxycinnamic acid, preparation method of sugar derivative and application of sugar derivative in cosmetics

The invention discloses a sugar derivative of hydroxycinnamic acid as well as a preparation method and application thereof in cosmetics. Specifically, the invention provides a sugar derivative of hydroxycinnamic acid. The compound is shown as a formula I in the specification. Compared with original hydroxycinnamic acid, the sugar derivative of hydroxycinnamic acid has better water solubility and stability, and has one or more effects of oxidation resistance, whitening, soothing, moisturizing, ultraviolet absorption and the like; when the composition is applied to cosmetics, light aging damage of skin can be relieved, and skin color can be brightened; .
Owner:SHANGHAI ZHONGYI DAILY CHEM CO LTD

Preparation method of anti-ultraviolet light absorption coating based on photoresist and nanocarbon

The invention discloses a preparation method of an anti-ultraviolet light absorption coating based on photoresist and nanocarbon, which comprises the following steps: using a nanocarbon material and photoresist as raw materials; the light absorption coating with low fluorescent background, low reflectivity and deep ultraviolet light aging resistance under the deep ultraviolet condition is obtained through the steps of preparing mixed turbid liquid, coating, pre-baking, removing photoresist through optical etching, removing residual photoresist, post-baking to form more holes and the like. When the low-background light absorption coating is applied to a deep ultraviolet fluorescence detector, compared with a traditional coating material of an organic adhesive and nanocarbon, the low-background light absorption coating provided by the invention has the advantages that the baseline of the detector is reduced by 67%, the baseline drift is reduced by 75%, and the baseline change degree under deep ultraviolet long-term aging is lower than 0.5%; the material shows excellent deep ultraviolet light aging resistance and extremely low fluorescence background, and can be applied to space telescopes, night vision devices, microscopes and various fluorescence detectors / sensors based on the characteristic of low reflectivity so as to obtain lower background and noise.
Owner:DALIAN INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES

Heat insulation aluminum foil packaging film for food packaging

The utility model belongs to the field of packaging films, particularly relates to a heat-insulating aluminum foil packaging film for food packaging, and aims to solve the problems that the quality guarantee period of food is shortened and the freshness and the quality of the food are reduced as the food is easily affected by light aging and oxidative deterioration due to the fact that the conventional packaging film is lack of effective barrier to ultraviolet rays and oxygen. According to the scheme, the film comprises a supporting frame and a winding drum, the winding drum is wound with a film body, and the film body comprises an ultraviolet-proof layer, a waterproof layer, an oxygen barrier layer, a protective layer, an aluminum foil layer, a contact layer and an antibacterial layer; the cutting assembly is arranged on the supporting frame and used for facilitating segmented cutting of the film body. Through the arrangement of the ultraviolet-proof layer and the oxygen barrier layer, the protection performance of the heat insulation aluminum foil packaging film for food packaging is effectively improved, damage of ultraviolet rays to food can be blocked, oxygen permeation can be prevented, and therefore the shelf life of the food is prolonged, and the freshness and quality of the food are kept.
Owner:JIANGYIN ANSHI COLOR PRINTING & PACKAGING

Medical cosmesis device with LED light source and body cosmesis system based on light therapy

The application belongs to the technical field of optical beauty, and discloses a medical beauty device with an LED light source and a body beauty system based on light therapy, which comprises the following steps: collecting multi-source data fusion and generating a skin health atlas through an ICP registration algorithm; based on the skin health atlas, a high tolerance area and a dense blood vessel area are segmented; laser wavelength, energy density and cooling parameters are allocated to each area; each dynamic threshold is adjusted in real time through a dynamic threshold; a risk level is determined and divided through multi-parameter fusion, and a hierarchical response mechanism is triggered to generate dynamic energy configuration parameters and safety control strategies; based on three-dimensional point cloud coordinates and space constraint conditions, a laser path planning is dynamically adjusted through a path re-planning algorithm to generate a light therapy execution log; based on the light therapy execution log, an efficacy evaluation report is generated to construct a photoaging risk atlas; through a reinforcement learning algorithm, the energy rule library, the parameters of the determination threshold and the weight coefficient of the registration algorithm are updated to form a closed-loop optimization.
Owner:YLIN ELECTRONICS CO LTD

An anti-aging Chinese medicine composition and its preparation method and application

The invention discloses an anti-aging Chinese medicine composition, which is composed of the following components by weight: 10-50 parts of snow lotus extract, 10-50 parts of motherwort extract, and 10-50 parts of tribulus terrestris extract. The anti-aging Chinese medicine composition of the invention is added to cosmetics as an anti-aging ingredient to prepare an anti-aging cosmetic stock solution. The anti-aging Chinese medicine composition of the invention is a pure natural Chinese medicine extract, and various components are mutually harmonized to exert a synergistic effect, and has excellent anti-aging effects, which are mainly manifested in anti-oxidation, mite inhibition, antibacterial and anti-photoaging. In addition, the Chinese medicine composition of the invention has low irritation to the skin, is safe and reliable, is a better cosmetic functional ingredient, and can be used to prepare anti-aging cosmetics.
Owner:CHINA PHARM UNIV

Ginseng polysaccharide, preparation method and application thereof

The application discloses a ginseng polysaccharide, a preparation method and application, and the ginseng polysaccharide is ginseng polysaccharide GP60, which is composed of glucose, galactose and arabinose, and the molar ratio of each monosaccharide is glucose: galactose: arabinose = 77.1: 16.8: 6.1; a new preparation method is adopted; after soaking and twice decocting, different proportions of 95% ethanol are added into the filtrate in batches; the obtained precipitate is added with water to prepare a solution with a relative density of 1.1 g / ml; a certain amount of the solution is taken, a certain proportion of chloroform and n-butanol is added, and a polysaccharide aqueous solution is prepared; the polysaccharide aqueous solution is added with 95% ethanol until the alcohol content reaches 60%; the solution is statically placed for 12 hours; centrifugal separation is carried out; the precipitate is collected; the collected precipitate is sequentially washed with 95% ethanol, anhydrous ethanol, isopropyl alcohol and ether; the solvent is volatilized; and the ginseng polysaccharide GP60 is obtained. The ginseng polysaccharide GP60 is non-toxic, has the effect of preventing light aging, and can be widely applied in the fields of food or health food, anti-light aging skin care products, washing and caring products and anti-light aging medicines.
Owner:BEIJING POLYTECHNIC

Use of a quantitative partial reprogramming system in the preparation of a drug for reversing skin aging

This invention provides an application of a quantitative partial reprogramming system in the preparation of drugs to reverse skin aging, belonging to the fields of regenerative medicine and medical aesthetics. The quantitative partial reprogramming system includes a nucleic acid delivery system or a small molecule induction system; skin aging includes photoaging-induced skin aging; reversing skin aging includes increasing the thickness of the dermis, increasing the density of type I collagen, and improving skin elasticity. The quantitative partial reprogramming system provided by this invention can fundamentally reverse the cellular aging clock and achieve structural regeneration, and can be applied to the preparation of drugs to reverse skin aging.
Owner:ZHUHAI HENGQIN ONA REGENERATIVE MEDICINE CO LTD

Use of plant-derived extracellular vesicles in the preparation of products for the prevention and treatment of photoaging and topical application compositions

The application discloses application of plant-derived extracellular vesicles in preparation of products for preventing and treating photoaging and a local application composition. The application takes Panax notoginseng as raw material to extract and purify the plant-derived extracellular vesicles, and the results show that the extracellular vesicles derived from Panax notoginseng can significantly treat or improve photoaging. The application explores the practical application of extracellular vesicles of fresh Panax notoginseng based on traditional Chinese medicine theory, and clarifies the molecular mechanism of the extracellular vesicles. In general, the extracellular vesicles derived from Panax notoginseng have wide application prospects in treatment of skin aging.
Owner:GUANGDONG MODERN HANFANG TECH CO LTD

Nanoemulsion composition, nanometer skin care product, preparation method and application

The invention provides a nano-emulsion composition, a nano skin care product, a preparation method and application, the nano-emulsion composition comprises a nano-emulsion and nucleic acid loaded on the surface of the nano-emulsion, and the nano-emulsion comprises a functional component, an emulsifier, an emollient, an antioxidant, a humectant and water; the functional component comprises a barrier repair lipid, the barrier repair lipid comprises sphingolipid, the sphingolipid comprises phytosphingosine, and the barrier repair lipid further comprises one or more of ceramide, free fatty acid and cholesterol; the mass ratio of the nucleic acid in the nanoemulsion composition is 0.1%-0.6%. The nanoemulsion composition has excellent permeability, so that the skin permeability of the nucleic acid is improved, and the bioavailability of the nucleic acid is improved; meanwhile, the nucleic acid can be specifically bound with adenosine A2A receptors distributed on keratinocytes, so that the binding speed of the nano-emulsion and the cells can be increased, the absorption and action effects of the nano-emulsion are specifically promoted, and the resistance of the skin to light aging is improved.
Owner:BEIJING TECH & BUSINESS UNIV

Application of alkannin in preparation of drugs for resisting photodermatosis

The invention discloses application of alkannin in preparation of drugs for resisting photodermatosis. The shikonin emulsion is used for external treatment of a constructed photoaging mouse model, and results show that after the shikonin emulsion is intervened for one week, mouse epidermis is thickened, namely, the mouse epidermis is recovered to a normal level, and after the shikonin emulsion is intervened for 14 days, mouse true dermatitis cells are also close to the normal level. When the shikonin emulsion intervenes for 7 days, cuticle pigment is reduced, the density and arrangement of dermal collagenous fibers are obviously improved, and after the shikonin emulsion intervenes for 14 days, the dermal collagenous fibers return to a normal state. The invention provides an important experimental basis for the treatment of photoaging by the shikonin emulsion through animal experiments. Furthermore, clinical tests are carried out, and the result shows that the external shikonin emulsion has a remarkable treatment effect on human actinic dermatitis clinically. Therefore, the invention provides a novel therapeutic drug and scheme for prevention and treatment of photodermatosis, and has good clinical application prospects and high clinical application values.
Owner:SHANGHAI CITY PUDONG NEW DISTRICT ZHOUPU HOSPITAL