95 results about "Aging skins" patented technology

A skin beautification cosmetic system comprising an iontophoresis device, an infrared (including far infrared) generator, an ultrasonic vibrator, and a cosmetic composition is disclosed. The system ensures effective action of moisturizing and whitening cosmetics without causing any problem in the skin. By specifying the type of cosmetic to be used, the system can ensure a more effective beautification action, can improve dry skin and aging skin which adversely affect the female skin, and can decompose and remove melanin. Moisturizing and / or whitening cosmetic components such as hydrophilic gel and ultrafine gel are applied to the face or skin or impregnated in a skin contact member section, following which iontophoresis high frequency vibration is applied to the face or skin for a prescribed period of time using an ultrasonic vibrator 3 with built-in high ionization iontophoresis device 2 and infrared generator 9.

The invention describes a system and method for revitalizing aging skin using electromagnetic energy that is delivered using a plurality of needles that are capable of penetrating the skin to desired depths. A particular aspect of the invention is the capability to spare zones of tissue from thermal exposure. This sparing of tissue allows new tissue to be regenerated while the heat treatment can shrink the collagen and tighten the underlying structures. Additionally, the system is capable of delivering therapeutically beneficial substances either through the penetrating needles or through channels that have been created by the penetration of the needles.

A skin beautification cosmetic system comprising an iontophoresis device, an infrared (including far infrared) generator, an ultrasonic vibrator, and a cosmetic composition is disclosed. The system ensures effective action of moisturizing and whitening cosmetics without causing any problem in the skin. By specifying the type of cosmetic to be used, the system can ensure a more effective beautification action, can improve dry skin and aging skin which adversely affect the female skin, and can decompose and remove melanin. Moisturizing and / or whitening cosmetic components such as hydrophilic gel and ultrafine gel are applied to the face or skin or impregnated in a skin contact member section, following which iontophoresis high frequency vibration is applied to the face or skin for a prescribed period of time using an ultrasonic vibrator 3 with built-in high ionization iontophoresis device 2 and infrared generator 9.

Human and mammalian skin undergoes a variety of changes associated with chronological aging. Various environmental factors, disease states and genetic disorders may accelerate both the appearance of aging skin and also the structural and functional changes associated with aging skin. Ultraviolet radiation from the sun is one of the classic known and well-defined means of accelerating or worsening the aging of the skin and this is frequently termed photoaging. Other environmental factors, such as oxidative stress, free radicals, environmental toxins such as ozone and cultural customs or habits such as tobacco smoking are other known probe accelerators in photo aging skin. A wide variety of other factors known and unknown contribute to accelerated or premature aging of the skin. This invention discusses methods where electromagnetic radiation, in particular, light, can be used to photobiomodulate the activity of living cells to delay, diminish, retard or even reverse the structural and functional effects of aging of the skin and other living cells and tissues. In particular methods described for improving the appearance, structure, function of aging skin, including up and down regulating the genotypic markers for the phenotype of aging skin.

Methods for stimulating proliferation of cells in the epidermis and dermis of mammalian skin are disclosed. The methods comprise the step of administering to an area of the skin a composition comprising a therapeutically effective amount of human placental alkaline phosphatase, or an active derivative. The composition can be administered topically or by injection. The invention also provides a regimen for restoring or maintaining the strength and thickness of aging skin, comprising periodically administering a composition by topical application. The invention further provides methods for stimulating proliferation of cells in the epidermis and dermis of transplanted skin. A composition for topical application is also provided by the invention.

Disclosed is a topical preparation for the treatment of topical itch in humans and animals. The said composition consists of Opuntia, Propolis, Stearic Acid, Beeswax, Vegetable Oil and β-sitosterol. Itch includes scratch reaction itch, anal itch, or irritant itch due to plants (e.g., poison ivy), insect bite, sunburn, chemical itch, eczema, pruritis dermatitis, diabetic skin itch, aging skin itch, foot-itch, chickenpox, jock itch, hives, itch of healing burns and wounds, dry winter skin itch, and stress-related scalp itch, etc

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive impairment, decreased libido, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

Beneficial topical compositions for treating scar or aging skin are provided. In one embodiment, the compositions include Bulbine frutescens, Centella asiatica and a phenol derived from olives, such as oleuropein. The composition may be used in the treatment of scars formed during surgery. The composition may also be used cosmeceutically in the treatment of aged skin, and may include phosphatidylserine, vitamins, and other beneficial anti-aging ingredients.

Human and mammalian skin undergoes a variety of changes associated with chronological aging. Various environmental factors, disease states and genetic disorders may accelerate both the appearance of aging skin and also the structural and functional changes associated with aging skin. Ultraviolet radiation from the sun is one of the classic known and well-defined means of accelerating or worsening the aging of the skin and this is frequently termed photoaging. Other environmental factors, such as oxidative stress, free radicals, environmental toxins such as ozone and cultural customs or habits such as tobacco smoking are other known probe accelerators in photo aging skin. A wide variety of other factors known and unknown contribute to accelerated or premature aging of the skin. This invention discusses methods where electromagnetic radiation, in particular, light, can be used to photobiomodulate the activity of living cells to delay, diminish, retard or even reverse the structural and functional effects of aging of the skin and other living cells and tissues. In particular methods described for improving the appearance, structure, function of aging skin, including up and down regulating the genotypic markers for the phenotype of aging skin.

Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and / or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and / or elasticity of aging skin, are also disclosed.

The present invention relates to a method for treating, preventing and improving the condition and / or aesthetic appearance of aging skin, particularly, treating, preventing, ameliorating, reducing and / or eliminating fine lines and / or wrinkles of skin, through meroterpene induced gene manipulation.

Method and compositions are provided for treating or preventing a skin pathology or disorder associated with diabetes and / or aging, by topical administration of at least one agent capable of restoring an impaired physiological condition of the skin associated with said skin pathology or disorder. Examples of such agents include PKC modulating agents, various adipokines and insulin signaling related molecules. In particular, restoration of the subcutaneous adipose tissue can overcome many of the diabetic skin pathologies and aging skin disorders and conditions.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

Beneficial topical compositions for treating scar or aging skin are provided. In one embodiment, the compositions include Bulbine frutescens, Centella asiatica and a phenol derived from olives, such as oleuropein. The composition may be used in the treatment of scars formed during surgery. The composition may also be used cosmeceutically in the treatment of aged skin, and may include phosphatidylserine, vitamins, and other beneficial anti-aging ingredients.

Method and compositions are provided for treating or preventing a skin pathology or disorder associated with diabetes and / or aging, by topical administration of at least one agent capable of restoring an impaired physiological condition of the skin associated with said skin pathology or disorder. Examples of such agents include PKC modulating agents, various adipokines and insulin signaling related molecules. In particular, restoration of the subcutaneous adipose tissue can overcome many of the diabetic skin pathologies and aging skin disorders and conditions.

The invention discloses a compound essential oil for skin care, which aims to satisfy the demand of people on natural skin care in the aspect of skin care. The compound essential oil disclosed by the invention comprises the following components in percentage by weight: 40-50% of jasmine essential oil, 8-12% of sandalwood essential oil, 8-12% of rose essential oil, 10-20% of tea tree essential oil, 10-20% of grapefruit essential oil, and 3-6% of lemon essential oil. The compound essential oil disclosed by the invention has various skin care effects such as whitening, moisturizing, fading scars, improving aging skins, and the like.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, muscular dystrophies, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

A composition comprising cartilage extract, grape seed extract and tomato extract was found to have remarkable anti-oxidant effect and free-radical inhibition. The tomato extract comprises lycopene. The composition which comprises a hydrophilic antioxidant, a lipophilic (hydrophobic) antioxidant, and a cartilage extract dramatically increases collagen synthesis in the dermis. Furthermore, the composition lowers collagenase activity and levels of advanced glycation end products (AGE). The signs of ageing, such as photoageing due to exposure to UV radiation, are related to the levels of collagen syntheses and free-radical oxidation. Compositions of the invention are intended for the treatment of ageing skin and the delaying of the onset of the signs of ageing in healthy skin.

Beneficial topical compositions for treating scar or aging skin are provided. In one embodiment, the compositions include Bulbine frutescens, Centella asiatica and a phenol derived from olives, such as oleuropein. The composition may be used in the treatment of scars formed during surgery. The composition may also be used cosmeceutically in the treatment of aged skin, and may include phosphatidylserine, vitamins, and other beneficial anti-aging ingredients.

The present invention provides an herbal composition for improving aging skin, comprising extract of Panax ginseng, Acanthopanax and Carthamus tinctorius. The composition of present invention can further comprise extract of Lignum aquilariae and Resina boswelliae carterii. The present invention also provides a method for improving aging skin of a subject, comprising administrating a composition comprising extract of Panax ginseng, Acanthopanax and Carthamus tinctorius to the subject.

The invention discloses a composition for skin repair and preparing method thereof. The formula consists of 35-50 parts of CGF, 1-5 parts of SOD, 1-5 parts of bioactive peptides, 8-12 parts of squalene, 6-10 parts of ceramide, 12-20 parts of CMC, 20-35 parts of tPA, 15-25 parts of microcapsule and an appropriate amount of deionized water. The invention adopts microencapsulation to wrap up the composition components. Transported by the transporters, the active factors are promoted to enter the skin dermis, which will have the tangible effect on complementing skin nutrient, regulating metabolism, accelerating pigment release, whitening complexion, smoothing wrinkles, anti aging and keeping the skin bright. The composition is also helpful to treat concealing blemishes, heal wound, smooth out facial wrinkles, crow and forehead wrinkles, fill facial hole and repair scar. Besides, it can help the aging skin to be repaired fast, complement part nutrient and accelerate the wound healing without scar and pigment. in short, it can regulate the growth and metabolism of the cell to prevent the aging of skin.

The present invention provides an herbal composition for improving aging skin, comprising extract of Panax ginseng, Acanthopanax and Carthamus tinctorius. The composition of present invention can further comprise extract of Lignum aquilariae and Resina boswelliae carterii.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, Alzheimer s disease, muscular dystrophies, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.

The present invention provides an improved skin care formulation for enhancing the overall quality of the skin and treating aging skin comprising cassia angustilfolia seed polysaccharide, dipeptide-4, glutamylamidoethyl indole, and kluyveromyces extract, in a cosmetically / dermatologically acceptable medium. The formulation improves skin quality by moisturizing and softening the skin, while protecting and repairing damaged sensitive skin, activating skin restructuration and stimulating collagen and keratin synthesis. Additionally, the formulation protects the skin from stress and oxidation, and reduces protein carbonylation and lipid peroxidation.

Provided are methods of determining the aging of skin or skin disorders or conditions by measuring and evaluating levels of skin-associated biomarker proteins in a subject's skin sample. In aspects, the levels of a subset of biomarker proteins are altered, e.g., increased or decreased, in aging / aged versus non-aging / young skin. Provided are methods for more individualized and direct treatments and therapeutic options for aging skin and / or skin disorders and conditions by determining the levels of those skin biomarker proteins that correlate with aging skin and / or certain skin attributes of a subject and administering treatment products and regimens that result in altering the levels of the biomarker proteins, in particular, toward levels of the proteins in non-aged and healthy skin.