273 results about "Scars" patented technology

The present disclosure provides a method and system for analyzing unipolar electrophysiological (EP) signals acquired by a multi-electrode catheter placed in a ventricle of a patient's heart. The method includes receiving unipolar EP signals, extracting unipolar far-field signals from the unipolar EP signals, and analyzing the extracted unipolar far-field signals to estimate the distribution of scar regions across a thickness of wall tissue of the ventricle. Using the estimated distribution, a unipolar far-field EP map showing the scar regions is generated. The method further includes displaying the unipolar far-field EP map including the scar regions to a user. The system comprises a display device and a processor configured to perform the steps of the method.

The invention provides a method for three-dimensional visualization of heart scars, a control device and a storage medium, and belongs to the technical field of three-dimensional heart modeling and visual display. The method comprises the following steps: matching a heart structure obtained by segmenting a pre-trained nnU-Net and a binary tag graph corresponding to a scar tissue with a myocardial shape shown by the binary tag graph of the heart structure by using a standard myocardial grid model as a template; and fitting deformation parameters of a standard myocardial grid model by using a deep learning regression model, and applying the deformation parameters to a standard grid to complete grid deformation so as to fit individual myocardial morphology. The heart shape prior is effectively utilized based on the template deformation method, so that the reconstructed three-dimensional model has higher anatomical consistency and fineness. And superposing the fitted three-dimensional myocardial grid model and the reconstructed scar tissue grid under the same coordinate for registration and superposition to realize image three-dimensional transparent myocardial scar visualization so as to accurately restore a continuous three-dimensional scar surface.

A system for capturing, identifying, and processing images and soft biometrics includes an image capture device, a pan and tilt device, a speaker for audio feedback, and a microphone for voice capture, all controlled by a computing device. Image capture is enhanced by detecting image focus, facial recognition matching, detecting the number of subjects and unwanted objects, and checking the cropped image by detecting whether eyes and mouth are open or closed, detecting redeye, detecting background color, detecting lighting conditions, and detecting subject location, pose and expression. Soft biometrics including scars, marks, and tattoos are also identified, cropped and classified.

The invention relates to a traditional Chinese medicine composition for treating burns and scalds, which is prepared from spur root and jade grape root according to a certain compatibility, and has the following effects: pain relieving: aching feeling is relieved or even disappears within 15 minutes; convergence: seepage of tissue fluid can be stopped within two hours; bacteriostasis: after the ointment is used, wounds which are just burnt and scalded or fester for several months can be gradually healed, and necrotic tissues can scab and fall off; skin grafting is not needed for burn and scald patients, scar tissue hyperplasia is avoided, and the disability rate of the patients is greatly reduced.

The invention discloses a quick classification method and system for human scars through visual calculation, and relates to the technical field of artificial intelligence, and the method comprises the following steps: S1, scar image collection and preprocessing: obtaining a human scar region image and shooting parameters, and carrying out the noise removal, illumination correction and scar region segmentation of an original image; s2, multi-modal scar feature extraction: based on the segmented scar region, extracting color features, texture features, morphological features and depth features; s3, feature fusion and dimension reduction; s4, constructing and training a lightweight scar classification model; s5, outputting a classification result and dynamically optimizing the model; according to the rapid classification method and system for the human body scars through visual calculation, through multi-modal feature fusion and improvement of a lightweight model, the classification accuracy is better than that of a traditional manual classification and single feature machine learning method, subjective differences of doctors are eliminated, and the classification objectivity is guaranteed.

The invention provides a nerve growth factor functionalized exosome as well as a preparation method and application thereof. The functionalized exosome can activate a Wnt / beta-catenin signal channel to maintain dryness of corneal limbal stem cells (LSCs) so as to promote corneal epithelium repair, can activate a cAMP signal channel to relieve inflammatory response and promote corneal nerve regeneration, and can be used for treating or relieving corneal chemical burns, including relieving inflammatory response, reducing stromal scar formation and inhibiting corneal neovascularization. Corneal epithelium repair and nerve regeneration are promoted.

The present invention relates to a skin suture device, and relates to the technical field of skin suture devices, which includes a fixing member and a tightening member; the fixing member includes a fixing strip, a movable block, and an adhesive strip, the fixing strip bottom is fixedly connected to the adhesive strip, the fixing strip top is raised to form a guide rail, the guide rail is slidably connected to the movable block, and the movable block top is fixedly connected to the fixed block, the fixing block is provided with a first through hole, the inner wall of the first through hole is fixedly connected to one end of a spring sheet; the tightening member is composed of a plurality of clips connected in sequence, the clips are provided with a ratchet groove, the ratchet groove engages and connects the other end of the spring sheet. Two fixing strips with the same structure are fixed to both sides of the skin by the adhesive strip, the fixing strips are made of flexible material, and the fixing strips can be bent and adjusted according to the shape of the wound. If the wound is arc-shaped, the fixing strip can be bent into an arc accordingly, so that the fixing strip fits the wound, thereby preventing the skin on both sides of the wound from being uneven or unable to be sutured, resulting in scars.

To provide a laminate excellent in tearing property while reducing environmental load.SOLUTION: A laminate comprises a substrate film, a primer layer, an adhesive layer, and a sealant film in this order, and includes a printed surface of an electrostatic ink composition adhered to the adhesive layer. The adhesive layer contains a solvent-free adhesive composition including a polyol component and a polyisocyanate component, its cured product, or a mixture thereof, and the adhesive strength of the adhesive layer is 1.0 N / 15 mm width or more. The laminate has a group of scratches, each consisting of multiple scratches that include through-holes.SELECTED DRAWING: Figure 1

The invention discloses a fusion polypeptide TGNL and application of neural stem cells modified by the fusion polypeptide TGNL in spinal cord injury repair. The fusion polypeptide TGNL is composed of a TAT penetrating domain, a GSTP targeting domain, an NICDi inhibition domain, an MMP-2 activation domain and a flexible Linker connecting the three domains, and the full-length amino acid sequence is as shown in SEQ ID NO. 1. The invention also provides a preparation method of the polypeptide, a neural stem cell (hNSCs-TGNL) for expressing the polypeptide and a construction method of the neural stem cell (hNSCs-TGNL). Experiments show that the fusion polypeptide TGNL can efficiently penetrate nerve cells, specifically target glial scars, is selectively activated by MMP-2, and promotes neural stem cells to differentiate into neurons by inhibiting Notch signals; the hNSCs-TGNL has high survival rate and strong penetrability in an in-vitro glial scar model, and can significantly promote motor function recovery, reduce injury volume, increase axon density and reduce glial scars in a rat spinal cord contusion model. The invention provides a novel candidate drug and a cell treatment strategy for clinical treatment of spinal cord injury, and has remarkable clinical application value.

A system for capturing, identifying, and processing images and soft biometrics includes an image capture device, a pan and tilt device, a speaker for audio feedback, and a microphone for voice capture, all controlled by a computing device. Image capture is enhanced by detecting image focus, facial recognition matching, detecting the number of subjects and unwanted objects, and checking the cropped image by detecting whether eyes and mouth are open or closed, detecting redeye, detecting background color, detecting lighting conditions, and detecting subject location, pose and expression. Soft biometrics including scars, marks, and tattoos are also identified, cropped and classified.

The invention discloses an abdominal operation postoperative scar nursing bellyband, and relates to the technical field of postoperative nursing, the abdominal operation postoperative scar nursing bellyband comprises an elastic band, the outer wall of the elastic band is provided with a detachable adjusting mechanism convenient for dismounting a gasket, through the structural arrangement, the abdominal operation postoperative scar nursing bellyband can realize the purpose that the gasket can be conveniently dismounted without dismounting a bellyband body; only the positions of the cloth and the wound are adjusted, so that the working difficulty of medical staff is simplified, wound tearing or secondary infection caused by re-winding of the bellyband on the wound of a patient is reduced, and the cloth can be independently detached so as to be directly replaced or applied with liquid medicine. And the recovery state of the wound can be observed through the detachable adjusting mechanism, so that the medical staff can conveniently adjust subsequent medication.

The invention discloses a compound scar ointment and a preparation method thereof, the ointment is prepared by decocting and concentrating Chinese herbal medicines such as salvia miltiorrhiza, cassia twig, radix paeoniae alba, rheum officinale, radix sophorae flavescentis, pepper, folium artemisiae argyi, lycopodium clavatum, garden balsam stem, pawpaw and borneol as raw materials and adding a matrix. The ointment has the effects of promoting blood circulation to remove blood stasis, relaxing tendons, activating collaterals, clearing heat and eliminating dampness, can effectively inhibit scar hyperplasia and promote scar softening and dissipation, and is suitable for treating various scars and acne marks. The ointment is simple in preparation process, green and environment-friendly, safe and non-irritant to use, good in clinical effect and wide in application prospect.

This invention discloses a multimodal imaging and multidimensional index evaluation software and hardware system for scars, involving an infrared, RGB, and stereoscopic three-modal imaging hardware system, and an intelligent calculation and monitoring software system for more than twenty scar evaluation indicators. The intelligent evaluation system for scars includes indicators such as perimeter, length, width, thickness, area, volume, color, roughness, consistency, elasticity, blood flow density, risk of continued scar growth, and color difference. This forms an objective, multidimensional, precise, and intelligent evaluation system for the scar diagnosis and treatment process, thereby assisting in diagnosis and treatment, as well as monitoring and tracking the entire life cycle of scars. This contributes to the visualization, objectification, and accuracy of the scar diagnosis and treatment process, providing doctors and patients with comprehensive diagnostic and treatment evidence and enabling tracking and tracing.

The formation of scars at a wound site is reduced by contacting the wound site with an effective dose of an inhibitor of focal adhesion kinase (FAK) formulated in a pullulan hydrogel. The release profile of the FAK inhibitor can be adjusted according to the nature of the wound, e.g., excisional wounds, burn wounds, etc.

According to the application of the arcangelisia loureiri extract in preparing the burn and scald wound healing medicine, the arcangelisia loureiri crude extract is obtained through extraction and concentration with a decoction method, and wound healing can be promoted by reducing the area of a rat skin wound, shortening the healing time of the rat skin wound, reducing the hyperplasia speed of the skin corium layer and promoting healing of the wound; the effects of remarkably promoting wound healing of burns and scalds and reducing scars are achieved.

The present invention comprises: a high-frequency oscillator that transmits high-frequency energy and includes a control unit; a high-frequency connecting line connected to the high-frequency oscillator; and a high-frequency transmission pad connected to the other end of the high-frequency connecting line and attached to the curve of facial skin in close contact with it, wherein the high-frequency transmission pad is configured such that an adhesive pad and a bipolar pad are integrated or separate. This invention relates to a non-invasive automatic facial lifting device using high-frequency energy that adheres closely to the curves of the face to be treated, thereby enabling uniform delivery of high-frequency energy to the skin, allowing for effective treatment without separate operation, minimizing the risk of excessive thermal damage to specific areas of the skin, resolving issues such as pain, scarring, and infection associated with existing invasive technologies, enhancing user convenience and safety through an automated control system and customized settings, and providing uniform treatment effects and reducing treatment time and fatigue by monitoring skin temperature in real time and delivering high-frequency energy according to set output, time, and patterns.

This item is primarily intended for use as nursing clothing for four-legged pets such as cats. The back opening, closed with a hook-and-loop fastener, is opened to the left and right sides of the back, the front and back legs are passed through the holes, and the garment is then closed to cover the neck and torso. The neck is covered by the cylindrical part at the bottom right of the front, top, and right side views. When the garment is worn, the abdominal opening, closed with a hook-and-eye fastener, can be opened to the left and right sides of the abdomen to allow for nursing care such as changing gauze applied to abdominal surgical scars.

The invention relates to the technical field of cosmetics, and particularly discloses an all-directional anti-acne repairing composition as well as a preparation method and application thereof. The comprehensive anti-acne repairing composition is prepared from the following components in parts by weight: 0.01 to 2 parts of flexible salicylic acid, 0.001 to 2 parts of rhodomyrtus tomentosa fruit extract, 0.001 to 0.5 part of quaternary ammonium salt, 0.01 to 5 parts of nicotinamide, 0.001 to 3 parts of herba centellae extract, 0.01 to 3 parts of phellinus linteus extract, 0.0001 to 2 parts of phaeodactylum tricornutum extract and 0.001 to 2 parts of bio-saccharide gum-1. The comprehensive anti-acne repairing composition provided by the invention can resist acnes comprehensively, achieves the effects of removing aged cutin, controlling oil, sterilizing, resisting inflammation, relieving and fading marks and moisturizing, and has a comprehensive repairing effect on various skin injuries including acne skin.

The application provides a Guizhou Rhamnus skin wound healing ointment and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions. The ointment comprises Guizhou Rhamnus concentrated extract and base excipients. The ointment has the functions of promoting skin wound healing, preventing swelling and pain, preventing infection and scar, reducing swelling and pain, removing blood stasis and promoting tissue regeneration, dredging channels and activating collaterals, and healthy skin tissue. The active ingredients of traditional Chinese medicine have the advantages of rapid healing and repair, obvious swelling and pain relief, delicate ointment texture, easy absorption by the skin, high safety, good stability, wide source of raw materials, easy collection, simple preparation process, batch processing, no toxic side effects on the health of production personnel, and no adverse effects on the environment.

The invention relates to burn and scald repair gel and a preparation method thereof.The burn and scald repair gel is composed of amorpha fruticosa extract, acrylic resin, an antioxidant and a penetrant, the amorpha fruticosa extract serving as an effective component has a good treatment effect on skin burns and scalds, and the prepared burn and scald repair gel can promote wound healing and reduce swelling and pain, and can be used for treating skin burns and scalds. The preparation can promote epidermis recovery and reduce scars, and is a green, safe and non-irritant burn and scald repair preparation.

The invention discloses a blue copper peptide composition for repairing scars and a preparation method of the blue copper peptide composition, and belongs to the technical field of preparation of biological medicine preparations. The composition is prepared from freeze-dried powder of copper blue peptide, polyquaternium-73, asiaticoside, nicotinamide, polydimethylsiloxane, betaine-propylene glycol ionic liquid and a gel matrix. According to the invention, the blue copper peptide is coated in a permeation enhancing system constructed by the betaine-propylene glycol ionic liquid and the HEPES, so that the enzymolysis loss of the blue copper peptide is reduced, and the biological activity of the blue copper peptide is maintained; a temperature-sensitive gel matrix is constructed by carboxyl esterified modified sodium alginate and poloxamer, the carboxyl esterified modified sodium alginate is prepared by grafting n-butyl alcohol to a hydrophilic main chain of sodium alginate through a Fischer esterification method, the gel matrix is in a liquid state at normal temperature, after the gel matrix is smeared on a scar part, the gel matrix is converted into semi-solid gel under the influence of body temperature, and slow and continuous release of blue copper peptide can be achieved. The traditional Chinese medicine composition has the effect of repairing scars and is suitable for chronic scars needing long-term nursing.

The invention discloses a hederacoside C deglycosylation derivative and a preparation method and application thereof.The hederacoside C deglycosylation derivative is prepared from hederacoside C through specific glycosidase hydrolysis, different products can be flexibly regulated and enriched on the basis of selectivity of different glycosidase to glucosidic bonds and glycosyl sites, the preparation method is simple, reaction conditions are mild, and the hederacoside C deglycosylation derivative is suitable for industrial production. The method is suitable for large-scale mass production. The hederacoside C deglycosyl derivative does not show obvious cytotoxicity to human immortalized keratinocytes, has the effect of promoting cell proliferation and the activity of promoting cell migration, and can obviously inhibit LPS (lipopolysaccharide)-induced cell apoptosis. Besides, the partial hederacoside C deglycosyl derivatives can reduce inflammatory factor level rise caused by wounds, remarkably promote wound healing and reduce formation of wound scars, and have good application prospects in preparation of drugs or skin care products for promoting wound repair.

The present invention discloses a biopsy forceps guiding catheter that can be used for zero-ray myocardial biopsy, comprising a catheter body, wherein a central cavity penetrating through both axial ends of the catheter body is provided inside the catheter body, at least one electrode element is provided at the first axial end of the catheter body, an airbag component is provided at the first axial end of the catheter body near the rear side of the electrode element, the electrode element is connected to an electrical connection assembly extending to the second axial end of the catheter body, the electrical connection assembly is connected to an electrocardiogram monitor, and the airbag component is connected to a ventilation assembly extending to the second axial end of the catheter body. The electrocardiogram and injury current in the cardiac cavity are recorded by the electrocardiogram monitor leads to select a site with a significant injury current for sampling, thereby reducing the influence of scars and fat tissue on the quality of the sampled sample, and the airbag component can drift and move with the blood, thereby solving the problem that the current biopsy forceps need to rely on X-ray guidance to be delivered into the ventricle and it is difficult to accurately obtain a specific layer of myocardium under the endocardium during sampling.

The invention provides a rhizoma bletillae composition as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine preparations. The core effective component of rhizoma bletillae is rhizoma bletillae polysaccharide, the rhizoma bletillae polysaccharide has the effects of film forming, hemostasis, targeted wound repair promotion and infection prevention, tea polyphenol and rhizoma bletillae are compounded for use, the tea polyphenol and rhizoma bletillae synergistically resist inflammation, the expression quantity of proinflammatory factors IL-1beta, TNF-alpha and IL-6 is reduced by inhibiting NF-kappa B and MAPK signal channels, the inflammatory cascade reaction is remarkably blocked, and the anti-inflammatory effect is achieved. Red, swollen and pain caused by inflammation are effectively relieved, and wound healing is accelerated. In addition, the rhizoma bletillae and the tea polyphenol can also generate a synergistic antibacterial effect, and compared with a single rhizoma bletillae component, the probability of wound infection is further reduced; the compounding use of the rhizoma bletillae and the tea polyphenol also inhibits the excessive deposition of collagen, reduces the scar area, reduces the scar hyperplasia degree, and makes up the blank of only promoting healing and not preventing scars for burns and scalds in the prior art.

The utility model provides a laser repairing head for scars. A positioner comprises a positioning cover and a handheld laser emitting device. The positioning cover is mounted at the head end of the handheld laser emitting device; the positioning cover comprises a connecting part at the upper half part and a positioning part at the lower half part; the connecting part is provided with two first hollow supporting rods opposite in position, the positioning part is provided with two second hollow supporting rods corresponding to the first hollow supporting rods in position, and the first hollow supporting rods and the second hollow supporting rods are connected through adjusting rods. A plurality of positioning holes are formed in the first hollow supporting rod and the second hollow supporting rod at equal intervals in the length direction, the two ends of the adjusting rod are each provided with an elastic locking head, and connection is achieved through cooperation between the elastic locking heads and the positioning holes; the elastic locking heads at the two ends are adjusted to the corresponding heights, the distance between the first hollow supporting rod and the second hollow supporting rod is adjusted, and therefore the height of the positioner is adjusted.

This application relates to the field of medical devices and discloses a needle withdrawal system for radiofrequency ablation devices that avoids scarring. Based on a standard radiofrequency ablation device, the system integrates a needle position detection device (real-time monitoring of depth and speed) and a needle tip temperature sensor. During needle withdrawal, the radiofrequency power is dynamically adjusted according to the withdrawal speed (higher power for faster speed); when the needle tip depth is less than a predetermined threshold (close to the body surface), the radiofrequency output is automatically stopped and a prompt to wait for cooling occurs; once the temperature drops below a safe threshold, a prompt indicates that the needle can be completely withdrawn. Through this closed-loop control, the thermal coagulation and end-point cooling processes of the needle track are precisely managed, effectively preventing thermal damage to the skin and subcutaneous tissue and significantly reducing scar formation.

The utility model relates to a kind of scar paste with temperature control memory effect and tension reduction function, the scar paste includes layer by layer arranged silica gel layer, shape memory metal layer, temperature control layer and waterproof layer;The silica gel layer includes the adhesive part of symmetrical adhesion in the two sides of skin wound when using, the two ends of the shape memory metal layer are connected with the adhesive part of corresponding side respectively, temperature control layer and waterproof layer are sequentially arranged on shape memory metal layer;The shape memory metal layer is used to change into preset contraction mode under skin temperature and / or the heating of temperature control layer and drive adhesive part shrink in tension reduction direction.It can drive the adhesive part of silica gel layer shrink in tension reduction direction under skin temperature compared with prior art, so as to achieve the effect of tension reduction and inhibiting scar hyperplasia, finally realize the effect of "scarless healing".

A split-kneepad design addresses quality-of-life issues for individuals that have undergone total knee replacement surgery. A pair of cushion inserts with an inner beveled angle that, when worn by the user, are oriented parallel to the axis of the vertical scar resulting from surgery, and are shaped and positioned so that the padding makes contact with the user's knee in regions adjacent to the scar, but do not result in direct compressive force on the scar itself when the user kneels or otherwise applies force to the kneepad.

The invention provides a scar medicine leading-in device which comprises a shell, a medicine supply assembly is arranged in the shell, a bottom shell is arranged at the bottom of the shell, a plurality of sliding frames are arranged on the bottom shell, sliding bases are arranged in the sliding frames in a sliding and clamping mode, a driving mechanism is arranged in the shell, and the driving mechanism is connected with the sliding bases so as to drive the sliding bases to slide in the sliding frames in a reciprocating mode. Pressing seats are arranged at the bottoms of the sliding seats, the pressing seats are connected with the sliding frame through a linkage mechanism so that sliding of the sliding frame can be converted into driving of the pressing seats to incline towards the moving direction of the sliding seat, a flexible sleeve is arranged on the shell, and the multiple sets of pressing seats are all arranged in the flexible sleeve. According to the medicine importer, scars can be quickly kneaded and softened, the scars are prevented from falling off due to excessive stress under the protection of the flexible sleeve, secondary injury to a patient is prevented, after the scars are kneaded and softened, medicine can permeate into the skin, the medicine effect is fully exerted, the recovery effect is improved, and medicine waste is reduced.

The utility model relates to the technical field of beauty appliances, in particular to an orbiculus oculi scar shortening device which comprises a columnar shell, a piston column sleeve horizontally extending out is arranged at the top of the columnar shell, a piston column is slidably installed in the piston column sleeve, and the end, extending out of the outside, of the piston column is connected with a massage head. The end, away from the massage head, of the piston column is hinged to a connecting rod through a far-end hinge column, the end, away from the piston column, of the connecting rod is hinged to a sliding block through a near-end hinge column, and the sliding block is slidably installed on an eccentric wheel and controlled by a micro motor fixedly installed on the eccentric wheel. According to the utility model, through the accurate vibration of the massage head, the orbiculus oculi muscle is relaxed, the blood circulation of the eye muscle is promoted, and the scar and crow's feet can be relieved.