149 results about "Scars" patented technology

The present disclosure provides a method and system for analyzing unipolar electrophysiological (EP) signals acquired by a multi-electrode catheter placed in a ventricle of a patient's heart. The method includes receiving unipolar EP signals, extracting unipolar far-field signals from the unipolar EP signals, and analyzing the extracted unipolar far-field signals to estimate the distribution of scar regions across a thickness of wall tissue of the ventricle. Using the estimated distribution, a unipolar far-field EP map showing the scar regions is generated. The method further includes displaying the unipolar far-field EP map including the scar regions to a user. The system comprises a display device and a processor configured to perform the steps of the method.

The invention relates to a traditional Chinese medicine composition for treating burns and scalds, which is prepared from spur root and jade grape root according to a certain compatibility, and has the following effects: pain relieving: aching feeling is relieved or even disappears within 15 minutes; convergence: seepage of tissue fluid can be stopped within two hours; bacteriostasis: after the ointment is used, wounds which are just burnt and scalded or fester for several months can be gradually healed, and necrotic tissues can scab and fall off; skin grafting is not needed for burn and scald patients, scar tissue hyperplasia is avoided, and the disability rate of the patients is greatly reduced.

The invention discloses a quick classification method and system for human scars through visual calculation, and relates to the technical field of artificial intelligence, and the method comprises the following steps: S1, scar image collection and preprocessing: obtaining a human scar region image and shooting parameters, and carrying out the noise removal, illumination correction and scar region segmentation of an original image; s2, multi-modal scar feature extraction: based on the segmented scar region, extracting color features, texture features, morphological features and depth features; s3, feature fusion and dimension reduction; s4, constructing and training a lightweight scar classification model; s5, outputting a classification result and dynamically optimizing the model; according to the rapid classification method and system for the human body scars through visual calculation, through multi-modal feature fusion and improvement of a lightweight model, the classification accuracy is better than that of a traditional manual classification and single feature machine learning method, subjective differences of doctors are eliminated, and the classification objectivity is guaranteed.

A system for capturing, identifying, and processing images and soft biometrics includes an image capture device, a pan and tilt device, a speaker for audio feedback, and a microphone for voice capture, all controlled by a computing device. Image capture is enhanced by detecting image focus, facial recognition matching, detecting the number of subjects and unwanted objects, and checking the cropped image by detecting whether eyes and mouth are open or closed, detecting redeye, detecting background color, detecting lighting conditions, and detecting subject location, pose and expression. Soft biometrics including scars, marks, and tattoos are also identified, cropped and classified.

The invention discloses a compound scar ointment and a preparation method thereof, the ointment is prepared by decocting and concentrating Chinese herbal medicines such as salvia miltiorrhiza, cassia twig, radix paeoniae alba, rheum officinale, radix sophorae flavescentis, pepper, folium artemisiae argyi, lycopodium clavatum, garden balsam stem, pawpaw and borneol as raw materials and adding a matrix. The ointment has the effects of promoting blood circulation to remove blood stasis, relaxing tendons, activating collaterals, clearing heat and eliminating dampness, can effectively inhibit scar hyperplasia and promote scar softening and dissipation, and is suitable for treating various scars and acne marks. The ointment is simple in preparation process, green and environment-friendly, safe and non-irritant to use, good in clinical effect and wide in application prospect.

This invention discloses a multimodal imaging and multidimensional index evaluation software and hardware system for scars, involving an infrared, RGB, and stereoscopic three-modal imaging hardware system, and an intelligent calculation and monitoring software system for more than twenty scar evaluation indicators. The intelligent evaluation system for scars includes indicators such as perimeter, length, width, thickness, area, volume, color, roughness, consistency, elasticity, blood flow density, risk of continued scar growth, and color difference. This forms an objective, multidimensional, precise, and intelligent evaluation system for the scar diagnosis and treatment process, thereby assisting in diagnosis and treatment, as well as monitoring and tracking the entire life cycle of scars. This contributes to the visualization, objectification, and accuracy of the scar diagnosis and treatment process, providing doctors and patients with comprehensive diagnostic and treatment evidence and enabling tracking and tracing.

The formation of scars at a wound site is reduced by contacting the wound site with an effective dose of an inhibitor of focal adhesion kinase (FAK) formulated in a pullulan hydrogel. The release profile of the FAK inhibitor can be adjusted according to the nature of the wound, e.g., excisional wounds, burn wounds, etc.

According to the application of the arcangelisia loureiri extract in preparing the burn and scald wound healing medicine, the arcangelisia loureiri crude extract is obtained through extraction and concentration with a decoction method, and wound healing can be promoted by reducing the area of a rat skin wound, shortening the healing time of the rat skin wound, reducing the hyperplasia speed of the skin corium layer and promoting healing of the wound; the effects of remarkably promoting wound healing of burns and scalds and reducing scars are achieved.

The present invention comprises: a high-frequency oscillator that transmits high-frequency energy and includes a control unit; a high-frequency connecting line connected to the high-frequency oscillator; and a high-frequency transmission pad connected to the other end of the high-frequency connecting line and attached to the curve of facial skin in close contact with it, wherein the high-frequency transmission pad is configured such that an adhesive pad and a bipolar pad are integrated or separate. This invention relates to a non-invasive automatic facial lifting device using high-frequency energy that adheres closely to the curves of the face to be treated, thereby enabling uniform delivery of high-frequency energy to the skin, allowing for effective treatment without separate operation, minimizing the risk of excessive thermal damage to specific areas of the skin, resolving issues such as pain, scarring, and infection associated with existing invasive technologies, enhancing user convenience and safety through an automated control system and customized settings, and providing uniform treatment effects and reducing treatment time and fatigue by monitoring skin temperature in real time and delivering high-frequency energy according to set output, time, and patterns.

This item is primarily intended for use as nursing clothing for four-legged pets such as cats. The back opening, closed with a hook-and-loop fastener, is opened to the left and right sides of the back, the front and back legs are passed through the holes, and the garment is then closed to cover the neck and torso. The neck is covered by the cylindrical part at the bottom right of the front, top, and right side views. When the garment is worn, the abdominal opening, closed with a hook-and-eye fastener, can be opened to the left and right sides of the abdomen to allow for nursing care such as changing gauze applied to abdominal surgical scars.

The invention relates to burn and scald repair gel and a preparation method thereof.The burn and scald repair gel is composed of amorpha fruticosa extract, acrylic resin, an antioxidant and a penetrant, the amorpha fruticosa extract serving as an effective component has a good treatment effect on skin burns and scalds, and the prepared burn and scald repair gel can promote wound healing and reduce swelling and pain, and can be used for treating skin burns and scalds. The preparation can promote epidermis recovery and reduce scars, and is a green, safe and non-irritant burn and scald repair preparation.

The invention discloses a blue copper peptide composition for repairing scars and a preparation method of the blue copper peptide composition, and belongs to the technical field of preparation of biological medicine preparations. The composition is prepared from freeze-dried powder of copper blue peptide, polyquaternium-73, asiaticoside, nicotinamide, polydimethylsiloxane, betaine-propylene glycol ionic liquid and a gel matrix. According to the invention, the blue copper peptide is coated in a permeation enhancing system constructed by the betaine-propylene glycol ionic liquid and the HEPES, so that the enzymolysis loss of the blue copper peptide is reduced, and the biological activity of the blue copper peptide is maintained; a temperature-sensitive gel matrix is constructed by carboxyl esterified modified sodium alginate and poloxamer, the carboxyl esterified modified sodium alginate is prepared by grafting n-butyl alcohol to a hydrophilic main chain of sodium alginate through a Fischer esterification method, the gel matrix is in a liquid state at normal temperature, after the gel matrix is smeared on a scar part, the gel matrix is converted into semi-solid gel under the influence of body temperature, and slow and continuous release of blue copper peptide can be achieved. The traditional Chinese medicine composition has the effect of repairing scars and is suitable for chronic scars needing long-term nursing.

The invention provides a rhizoma bletillae composition as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine preparations. The core effective component of rhizoma bletillae is rhizoma bletillae polysaccharide, the rhizoma bletillae polysaccharide has the effects of film forming, hemostasis, targeted wound repair promotion and infection prevention, tea polyphenol and rhizoma bletillae are compounded for use, the tea polyphenol and rhizoma bletillae synergistically resist inflammation, the expression quantity of proinflammatory factors IL-1beta, TNF-alpha and IL-6 is reduced by inhibiting NF-kappa B and MAPK signal channels, the inflammatory cascade reaction is remarkably blocked, and the anti-inflammatory effect is achieved. Red, swollen and pain caused by inflammation are effectively relieved, and wound healing is accelerated. In addition, the rhizoma bletillae and the tea polyphenol can also generate a synergistic antibacterial effect, and compared with a single rhizoma bletillae component, the probability of wound infection is further reduced; the compounding use of the rhizoma bletillae and the tea polyphenol also inhibits the excessive deposition of collagen, reduces the scar area, reduces the scar hyperplasia degree, and makes up the blank of only promoting healing and not preventing scars for burns and scalds in the prior art.

The utility model provides a laser repairing head for scars. A positioner comprises a positioning cover and a handheld laser emitting device. The positioning cover is mounted at the head end of the handheld laser emitting device; the positioning cover comprises a connecting part at the upper half part and a positioning part at the lower half part; the connecting part is provided with two first hollow supporting rods opposite in position, the positioning part is provided with two second hollow supporting rods corresponding to the first hollow supporting rods in position, and the first hollow supporting rods and the second hollow supporting rods are connected through adjusting rods. A plurality of positioning holes are formed in the first hollow supporting rod and the second hollow supporting rod at equal intervals in the length direction, the two ends of the adjusting rod are each provided with an elastic locking head, and connection is achieved through cooperation between the elastic locking heads and the positioning holes; the elastic locking heads at the two ends are adjusted to the corresponding heights, the distance between the first hollow supporting rod and the second hollow supporting rod is adjusted, and therefore the height of the positioner is adjusted.

The utility model relates to a kind of scar paste with temperature control memory effect and tension reduction function, the scar paste includes layer by layer arranged silica gel layer, shape memory metal layer, temperature control layer and waterproof layer;The silica gel layer includes the adhesive part of symmetrical adhesion in the two sides of skin wound when using, the two ends of the shape memory metal layer are connected with the adhesive part of corresponding side respectively, temperature control layer and waterproof layer are sequentially arranged on shape memory metal layer;The shape memory metal layer is used to change into preset contraction mode under skin temperature and / or the heating of temperature control layer and drive adhesive part shrink in tension reduction direction.It can drive the adhesive part of silica gel layer shrink in tension reduction direction under skin temperature compared with prior art, so as to achieve the effect of tension reduction and inhibiting scar hyperplasia, finally realize the effect of "scarless healing".

The invention provides a scar medicine leading-in device which comprises a shell, a medicine supply assembly is arranged in the shell, a bottom shell is arranged at the bottom of the shell, a plurality of sliding frames are arranged on the bottom shell, sliding bases are arranged in the sliding frames in a sliding and clamping mode, a driving mechanism is arranged in the shell, and the driving mechanism is connected with the sliding bases so as to drive the sliding bases to slide in the sliding frames in a reciprocating mode. Pressing seats are arranged at the bottoms of the sliding seats, the pressing seats are connected with the sliding frame through a linkage mechanism so that sliding of the sliding frame can be converted into driving of the pressing seats to incline towards the moving direction of the sliding seat, a flexible sleeve is arranged on the shell, and the multiple sets of pressing seats are all arranged in the flexible sleeve. According to the medicine importer, scars can be quickly kneaded and softened, the scars are prevented from falling off due to excessive stress under the protection of the flexible sleeve, secondary injury to a patient is prevented, after the scars are kneaded and softened, medicine can permeate into the skin, the medicine effect is fully exerted, the recovery effect is improved, and medicine waste is reduced.

The utility model discloses a novel birthmark scar medicine skin penetration device which comprises an outer shell, an inner shell is installed on the lower side of the outer shell through a communicating pipe, a vibration needle is installed at the bottom of the communicating pipe through a telescopic installation plate assembly, and an adsorption layer is detachably installed at the bottom of the vibration needle. Vertical plates are fixedly connected to the left side and the right side of the top of the adsorption layer, a plurality of cylindrical clamping blocks extending to the outer side are slidably connected to an inner cavity of the inner shell, and long grooves used in cooperation with the cylindrical clamping blocks are formed in the surfaces of the vertical plates. The cylindrical clamping block is retracted into the inner cavity of the inner shell by sliding the cylindrical clamping block, so that the vertical plate is unlocked, and then the adsorption layer slides down to be separated from the lower end of the inner shell, so that the adsorption layer is quickly and conveniently disassembled and disinfected.

A computer-implemented method for determining scar segmentation includes receiving a medical image of an object to be segmented acquired after an application of a low-dose of contrast agent and determining a scar segmentation mask by applying a trained artificial neural network to the medical image. The low-dose of the contrast agent includes less contrast-agent than a standard full-dose of the contrast agent.

The application relates to the technical field of medical materials, and particularly discloses a kind of bionic medical tissue adhesive and a preparation method thereof.A kind of bionic medical tissue adhesive is made of raw materials containing the following weight parts: alpha-cyano octyl acrylate 30-35 parts;degradable polymer material 20-30 parts;gelatin 1-5 parts;polyethylene glycol 2-5 parts;sterile water 20-30 parts;sodium alginate 2-4 parts;antibacterial agent 8-10 parts;stabilizing protective agent 1-3 parts;mussel extract 1-3 parts;slug extract 1-3 parts;its preparation method is: polyethylene glycol, sterile water, sodium alginate, antibacterial agent, stabilizing protective agent, mussel extract and slug extract are mixed, and stirred uniformly;then alpha-cyano octyl acrylate, degradable polymer material and gelatin are added, heated to 40-60 DEG C and stirred for 20-40 min, and the bionic medical tissue adhesive can be obtained.The bionic medical tissue adhesive of the application can better handle the skin tissue changes occurring in the proliferation period, so that the prominence of the scar formed in the later period is smaller, the whole is relatively flat and smooth, and thus the scar is greatly improved.

Disclosed are adhesive medical films incorporating one or more cationic steroidal antimicrobial (CSA) compounds. The adhesive medical film is in the form of a tape, dressing, or sheet, configured for contact against dermal tissue to provide securement of medical devices, wound care, wound closure, and / or scar prevention. The adhesive medical film includes (i) a polymer adhesive (e.g., pressure-sensitive adhesive) in which one or more CSA compounds are distributed, and (ii) optionally, a backing substrate upon which the polymer adhesive is disposed. Examples of polymer adhesives include polyacrylate and silicone adhesives. The adhesive medical films, when used, reduce microbial colonization and / or growth, both on the films during storage and at a dermal site, as compared to the same adhesive medical film without incorporated CSA compounds.

The present application relates to the field of biotechnology, in particular to the application of Radix Rabdosiae Rubescens derived exosomes in the preparation of a drug for promoting wound healing, wherein the prepared Radix Rabdosiae Rubescens derived exosomes are uniform in size, good in appearance, can promote cell proliferation, have good effects of promoting fibroblast migration and reducing scar formation; and a scar-free wound healing hydrogel containing Radix Rabdosiae Rubescens derived exosomes is also provided, wherein the hydrogel can encapsulate rEVs or ORI, can effectively increase the proportion of type III collagen in the new skin tissue, effectively reduce the formation of scars, effectively promote the healing of deep second-degree burn wounds, and effectively inhibit the MMT process of macrophages in the wound healing process, and has a wide application prospect in the field of scar prevention and treatment.

This invention belongs to the field of bioengineering technology and discloses a method for specific targeting and scarless simultaneous elimination blue KPC‑2 Gene and IncL plasmid sgRNA sequences, CRISPR / Cas9 vector system and applications. This system targets the sgRNA of the IncL plasmid. blue KPC‑2 The IncL-type plasmid of the gene was designed with an sgRNA that specifically recognizes the conserved sequence at its origin of replication, thus eliminating the drug resistance gene while disrupting the plasmid's replication ability. Conjugation transfer to recipient bacteria significantly improved vector delivery efficiency. An arabinose-inducible promoter was used to control Cas9 gene expression, improving system stability and editing success rate. The vector carries a sucrose-inducible self-eliminating gene, enabling controlled vector self-elimination. This system is not a simple superposition but rather constitutes a time-controlled operational flow: efficient delivery via conjugation, controlled cleavage via induction, and finally, induced self-elimination.

The utility model discloses a scar repair functional dressing, which comprises a skin-friendly application, the non-woven fabric block is arranged at the central position of the sticking surface of the skin-friendly application; the medicine-containing patch is arranged on the non-woven fabric block; wherein through holes are formed in the center of the non-woven fabric block and the center of the medicine-containing patch, and the area, where the non-woven fabric block is located, of the skin-friendly patch is an ethylene-based thin film layer. According to the dressing with the scar repairing function, the form of liquid medicine is adopted, scar removing liquid is soaked into the medicine-containing patch, after the medicine-containing patch is pasted, redundant liquid medicine can be absorbed by the non-woven fabric block and is prevented from seeping out of the skin-friendly patch, and after the liquid medicine of the medicine-containing patch is absorbed, the non-woven fabric block can be supplied to the medicine-containing patch, so that sufficient absorption of the liquid medicine is guaranteed.

The utility model provides a shape correcting and maintaining device used after a navel reconstruction operation. The device comprises a shaping body, a base plate, a tensioning device and a locking device, the shaping body is of a hollow hard elastic structure, an arc-shaped closed face is arranged at the end, inserted into the navel, of the shaping body, the other end of the shaping body is open, and a plurality of notches are formed in the portion, close to the open end, of the shaping body. At least one group of symmetrical wing plates are arranged on the outer edge of the opening end of the shaping main body; at least two groups of tensioning devices are arranged, and one end of each group of tensioning device is fixed on the corresponding wing plate; and each group of tensioning devices is correspondingly provided with a group of locking devices for locking the tensioning devices, and the locking devices are fixed on the base plate. According to the utility model, stable and reliable shape and size can be provided for the rebuilt navel, so that a patient can obtain a satisfactory and beautiful navel, and meanwhile, the formation of scars around the navel is reduced.

Mastopexy implants for breast lifts create new tissue planes in the breast that provide a more durable lift, and are particularly useful in breast lifts with a high content of fatty tissue; the implants can be implanted through small incisions using blunt dissection, reducing operating time, and providing a better aesthetic appearance with minimal scarring; the implants are designed to be temporary, and have sufficient retention strength to allow the new tissue planes to form and support the lifted breast without any significant loss of support during this regenerative period.

Disclosed herein are improved methods and compositions of de novo synthesis of nucleic acids by cyclic extension using nucleotides that have an N-linked or O-linked scar or protecting group, and subsequent removal of the scar or protecting group. During polymerase-nucleotide conjugate-based polynucleotide synthesis or after the synthesis is completed, nucleobases having a scar from linker cleavage can be converted back into native form by removal of the scars from the nucleobases. Secondary structure formation in the nascent chain, which may inhibit extension reactions, is suppressed by the use of monomers with protected nucleobases that prevent Watson-Crick base pairing and / or other structures. After the synthesis is completed, the nucleobases can be converted back into native form by palladium-based removal of the protecting groups.

The utility model discloses an elastic scar patch, and belongs to the field of medical supplies. The elastic scar patch comprises a substrate layer, an air bag and an elastic backing layer which are sequentially arranged, the shape of one side of the substrate layer is matched with the shape of the outer surface of one side of the air bag, one side of the substrate layer is attached to the surface of the air bag, the elastic backing layer is used for fixing the substrate layer and the air bag to the skin surface, and the other side of a substrate assembly is attached to the skin surface. The air bag is used for applying pressure to the substrate layer and the elastic backing layer, and the substrate layer is used for evenly applying the pressure of the air bag to the skin. The shape of one side of the substrate layer is matched with the shape of the outer surface of one side of the air bag, one side of the substrate layer is attached to the surface of the air bag, the other side of the substrate assembly is attached to the surface of the skin, the pressure of the air bag can be evenly applied to the skin, and the problem that in the prior art, the effective pressure applying area of the air bag is small is solved.

The invention relates to the field of beauty, in particular to a beauty product and application thereof. In particular, the present invention relates to a cosmetic product comprising a concentrate and ultrasonically treated hyaluronic acid, the hyaluronic acid having an average molecular weight in the range of from 100 kD to 500 kDa; wherein the concentrate comprises at least one growth factor and at least one cytokine. The invention also relates to the use of said cosmetic product for promoting tissue regeneration, improving skin quality, reducing skin wrinkles and scars, and reducing skin irritation and flaws.

The utility model relates to the technical field of nuclear medical instruments, in particular to a self-adhesive breathable nuclide scar repair patch. The self-adhesive breathable nuclide scar repair patch comprises a waterproof layer, an active layer and an adhesion layer, the adhesion layer is connected to one side of the waterproof layer, and the active layer is arranged in the waterproof layer; a first vent hole is formed in the waterproof layer in the thickness direction of the waterproof layer, and the active layer is arranged away from the first vent hole. The nuclide scar repair paste can be fixed on a human body through the adhesion layer, the application is convenient, the application time and difficulty can be reduced, and the risk of radiation exposure of medical staff is avoided. The active layer is arranged in the waterproof layer, and nuclide leakage in the active layer can be prevented. The first vent holes are formed in the waterproof layer, the breathability of the nuclide scar repair patch can be improved through the first vent holes, the comfort level of the patch is improved, and in order to prevent the active layer from leaking through the first vent holes, the active layer is arranged away from the first vent holes.

The invention discloses a traditional Chinese medicine composition for inhibiting and fading scar hyperplasia and a preparation method of the traditional Chinese medicine composition, and belongs to the field of traditional Chinese medicine compositions for fading scars. 5 to 15 parts of a gel matrix; 10 to 25 parts of an oil phase component; 3-8 parts of an emulsifier and a thickener; and the balance of water. Wherein the active traditional Chinese medicine component consists of 1-5 parts of calculus bovis factitius, 1-3 parts of artificial musk, 3-10 parts of cowherb seed, 3-10 parts of golden cypress, 2-8 parts of frankincense and 2-8 parts of myrrh. The traditional Chinese medicine composition for inhibiting and fading scar hyperplasia and the preparation method of the traditional Chinese medicine composition have the beneficial effects that the traditional Chinese medicine composition for inhibiting and fading scar hyperplasia and the preparation method of the traditional Chinese medicine composition are provided, all the medicines are combined to jointly achieve the effects of promoting blood circulation to remove blood stasis, dredging collaterals, removing stasis, resisting inflammation and promoting tissue regeneration and directly refer to the pathogenesis core of scar hyperplasia, and an oil-in-water (O / W) latex dosage form is adopted, so that the traditional Chinese medicine composition has the refreshing effect of gel and the moistening effect of cream, and is easy to coat and good in air permeability.