A method of removing a dye tattoo from a region of
skin comprising creating voids in the region of
skin, the voids extending from a surface of the epidermis into the
dermis, applying a removal compound to the region of
skin, degrading the dye by the action of the removal compound, and removing the removal compound from the region of skin. A
system for dye
tattoo removal comprising a sensor for sensing a location of the surface of a region of tattooed skin of a subject, a dermal penetration device for creating voids in the region of skin, the voids extending from a surface of the epidermis into the
dermis, a controller responsive to the sensor to control the dermal penetration device to create voids into but not through the
dermis in the region of skin, and a dispenser for dispensing a removal compound to the region of skin.