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270 results about "Surface plasmon resonance" patented technology

Surface plasmon resonance (SPR) is the resonant oscillation of conduction electrons at the interface between negative and positive permittivity material stimulated by incident light. SPR is the basis of many standard tools for measuring adsorption of material onto planar metal (typically gold or silver) surfaces or onto the surface of metal nanoparticles. It is the fundamental principle behind many color-based biosensor applications, different lab-on-a-chip sensors and diatom photosynthesis.

Cardiovascular disease risk prediction method and system

The invention relates to a cardiovascular disease risk prediction system, which comprises a user terminal module, an edge computing module, a cloud intelligent module, an application service module and a system support module, wherein the user terminal module comprises an intelligent sensing equipment cluster unit and a mobile terminal data entry unit; and the intelligent sensing equipment cluster unit adopts a millimeter wave radar-PPG fusion sensor, monitors subcutaneous 0.5 mm depth arterial vibration through a 60GHz radar array, is aligned with a photoplethysmogram signal in a space-time manner, and performs user data acquisition based on a surface plasma resonance chip. According to the cardiovascular disease risk prediction method and system, real-time signal processing is realized by adopting JetsonAGX through a heterogeneous calculation architecture, medical image accelerated calculation is performed by using NVIDIAClara, non-out-of-domain joint modeling of data of hospitals is supported through federal learning, privacy protection reasoning based on homomorphic encryption is realized, and full-process closed-loop management is realized by adopting a layered modular architecture. And the accuracy of cardiovascular disease risk prediction is improved.
Owner:THE SIXTH MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

Peanut oil impurity detection method based on image recognition analysis

The invention discloses a peanut oil impurity detection method based on image recognition analysis, and relates to the technical field of computer vision, and the peanut oil impurity detection method comprises the following steps: carrying out impurity targeted marking on an oil sample; adopting dual-wavelength laser to excite the oil sample subjected to impurity target marking, synchronously acquiring a fluorescence image, and marking the coordinates of a suspicious composite impurity region by utilizing an FRET fluorescence intensity ratio; metal impurities and fiber impurities are distinguished according to the plasma formant position, and nanoscale impurity morphology data are formed; detecting unmarked transparent nanoparticles, triggering surface acoustic wave assisted detection, and outputting impurity motion feature codes; inputting the FRET fluorescence intensity ratio, the nanoscale impurity morphology data and the impurity motion trail features into a graph neural network classifier based on an attention mechanism, and performing joint interpretation on impurity types; and sorting and filling the oil sample according to an impurity classification result. The comprehensive performance of impurity detection is remarkably improved through a multi-mode sensing cooperation mechanism.
Owner:FOSHAN JIANHUA GRAIN & OIL CO LTD +1

Novel reaction tube

The utility model relates to a reaction tube, in particular to a reaction tube for CRI SPR (CRI Surface Plasmon Resonance) detection. The reaction tube comprises a cover body and a tube body, the tube body comprises a tube body opening, the cover body can cover the tube body opening, the cover body comprises a containing cavity, and a solid reagent such as a Cas protein freeze-dried body or a CRI SPR detection system freeze-dried body is arranged in the containing cavity. The utility model solves the technical problem that the cover needs to be opened in two-step reaction, for example, the technical problem that the cover needs to be opened in a CRI SPR (CRI Surface Plasmon Resonance) detection two-step method.
Owner:SHANGHAI TOLO BIOTECH CO LTD

Titanium nitride doped fluoride-free photo-thermal super-hydrophobic coating as well as preparation method and application thereof

The invention provides a titanium nitride doped fluoride-free photo-thermal super-hydrophobic coating and a preparation method and application thereof.The titanium nitride doped fluoride-free photo-thermal super-hydrophobic coating is prepared from polydimethylsiloxane modified titanium nitride, hydrophobic nanoparticles and an adhesive and has the excellent local surface plasma resonance effect and photo-thermal effect; meanwhile, the coating is of a rough and uniform micro-nano hierarchical structure, dynamic water can be efficiently removed, icing can be delayed, the surface temperature can reach 12 DEG C only through irradiation of one sunlight intensity in the environment of-30 DEG C, and rapid deicing can be achieved. The coating has good functions of self-cleaning, anti-icing, deicing, defrosting and the like, renewable solar energy is utilized, and the coating is green, environment-friendly, energy-saving and emission-reducing. Meanwhile, the super-hydrophobic surface of the coating can effectively delay icing and inhibit ice adhesion. According to the coating, organic combination of an active deicing strategy and a passive deicing strategy is achieved based on the synergistic effect of the super-hydrophobicity and the photothermal effect.
Owner:NAT INNOVATION INST OF DEFENSE TECH PLA ACAD OF MILITARY SCI

Micro-nano optical fiber probe for biochemical component detection based on infrared spectrum and detection equipment

The invention provides a micro-nano optical fiber probe for biochemical component detection based on infrared spectroscopy and detection equipment, and a preparation method of the micro-nano optical fiber probe comprises the following steps: S1, selecting one section of a multimode quartz optical fiber as a sensing area, and then removing a cladding layer and a coating layer of the sensing area to expose a bare fiber; s2, dripping a mixed acid solution prepared from hydrofluoric acid and citric acid to the bare fiber to corrode the bare fiber, and then cleaning and blow-drying; immersing the treated multimode quartz optical fiber into a silane coupling agent solution, reacting for 0.5-1 hour, and then drying; s3, immersing the multimode quartz optical fiber treated in the step S2 into a solution containing silver nanoparticles, and reacting for 10-20 minutes to obtain an optical fiber modified by the silver nanoparticles; and S4, sputtering a gold layer on the surface of the silver-modified optical fiber by adopting a vacuum magnetron sputtering technology to obtain the micro-nano optical fiber probe with the silver-gold film layer. After the surface of the silver nanostructure is covered with the gold film, oxygen, water, corrosive molecules and the like are effectively prevented from making direct contact with silver. In addition, both the gold and the silver can support a surface plasmon resonance (SPR) effect, and particularly, the prepared detection equipment can ensure the sensitivity of the SPR.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Multi-dimensional light pressure regulation and control method and device based on metasurface microstructure array

The invention relates to the technical field of optical metasurface and light field regulation and control, in particular to a light pressure multi-dimensional regulation and control method and device based on a metasurface microstructure array. The method comprises the following steps: designing and preparing a metasurface microstructure array, wherein the microstructure array is composed of a plurality of sub-wavelength scale three-dimensional microstructure units arranged on a dielectric substrate; surface plasmon resonance is excited by adjusting structural parameters of the three-dimensional microstructure units and adjusting working parameters of a light source acting on the microstructure array, and near-field localization and enhancement are achieved. And calculating, regulating and controlling the light pressure borne by the metasurface microstructure array based on the Maxwell stress tensor. The method can keep a remarkable light pressure enhancing effect in a wide spectrum range of 380-1300 nm, and is suitable for various material systems such as silver, gold and the like. The method can be applied to the fields of optical tweezers systems, optical control devices, precision measurement and the like, and has the advantages of flexible design, simplicity and convenience in preparation, high regulation and control precision and the like.
Owner:TIANJIN UNIV

Cu2O-based heterogeneous composite material as well as preparation method and application thereof

The invention provides a Cu2O-based heterogeneous composite material as well as a preparation method and application thereof. The preparation method comprises the following steps: coating the surface of a Cu2O hollow sphere substrate with a carbon layer, and depositing layered double hydroxides (LDHs) and metal palladium (Pd) nanoparticles on the carbon layer. According to the material, through a Cu2O-carbon layer-LDHs-Pd multistage heterostructure design, space optimization of light absorption, charge transfer and catalytic sites is realized; cu2O-carbon layer-LDHs interface coupling promotes directed migration of photo-induced electron-hole pairs, and the surface plasmon resonance effect of Pd nanoparticles enhances the charge separation efficiency; the LDHs optimizes a charge transfer path through surface oxygen vacancy or metal valence cycle, so that synergistic oxidation of non-free radicals and free radicals is realized, the organic matter degradation efficiency is remarkably improved, the oxidation path is widened, and the performance bottleneck of a single material is broken through.
Owner:CHINA THREE GORGES CORPORATION +1

Bimetal optical fiber SPR (Surface Plasmon Resonance) sensor based on silver core-gold shell nanoparticles

The application discloses a bimetallic optical fiber SPR sensor based on silver core-gold shell nanoparticles, comprising: an optical fiber, the outer surface of which is provided with a sensing area; and the metal functional layer is arranged on the sensing area, the metal functional layer comprises dispersedly stacked silver nanoparticles, and the outer surfaces of the silver nanoparticles are coated with gold films. The metal functional layer of the sensor is composed of the metal nanoparticles, and compared with a traditional metal film SPR sensor, the specific surface area and porosity of metal are remarkably improved, and the detection sensitivity of the SPR sensor can be improved; silver nanoparticles are adopted as a main metal material, SPR sensing is greatly promoted, the silver nanoparticles are coated with a gold film to form isolated bimetal nanoparticles, the chemical stability of the silver nanoparticles is improved, the sensor is endowed with common characteristics of gold and silver, and the detection performance is remarkably improved.
Owner:天津大学浙江研究院

Trace biochemical sensor based on deep sub-wavelength singular point resonance

The invention discloses a trace biochemical sensor based on deep sub-wavelength singular point resonance, the sensor comprises an upper metal layer, a middle dielectric layer and a lower metal layer which are stacked in sequence from top to bottom, the upper metal layer is a deep sub-wavelength singular point resonance structure pattern, the lower metal layer is an excitation microstrip line, and the middle dielectric layer is a deep sub-wavelength singular point resonance structure pattern. Resonance of the deep sub-wavelength singular point resonance structure pattern is excited by the excitation microstrip line. By effectively adjusting the rotation angle of the deep sub-wavelength singular point resonance structure graph, the resonance mode field of the sensor is gradually evolved into a singular point resonance mode from a hybrid bonding and anti-bonding intrinsic resonance mode. According to the sensor, the equivalent working wavelength of the deep sub-wavelength artificial local surface plasmon resonance unit is compressed, and the electromagnetic field enhancement characteristic of a singular point resonance mode and the square root dependency relationship of tiny dielectric disturbance are combined, so that the high-sensitivity resolution of trace biochemical quantity is realized in a low-frequency microwave band.
Owner:SOUTHEAST UNIV

SPR image optimization processing method based on image segmentation and edge enhancement

The invention discloses an SPR (Surface Plasmon Resonance) image optimization processing method based on image segmentation and edge enhancement, which comprises the following steps: acquiring SPR image data, and preprocessing to generate standardized SPR image data; inputting a structure boundary extraction model constructed based on CGNet, generating a structure boundary label graph, and aligning the structure boundary label graph with the image; gradient amplitude and local entropy mutation detection is executed, and an artifact guide graph is generated; respectively inputting the standardized image into details and context branches of the improved CSDNet, and extracting edge and semantic feature maps; inputting a guide perception gating module, executing structure enhancement and artifact suppression fusion, and generating a fusion feature map; inputting into a multi-scale detail recovery module, and outputting an edge enhanced image; and executing structural similarity and marginal definition scoring based on the original image and the enhanced image, and generating an optimization result. According to the method, synchronous optimization of SPR image edge enhancement and structure maintenance is realized, and the image definition and diagnosis availability are remarkably improved.
Owner:SUZHOU YAOSHENG INTELLIGENT TECH CO LTD

A nucleic acid aptamer binding to CD5 protein and its application

The present invention discloses a nucleic acid aptamer binding to CD5 protein, the sequence of which is shown in SEQ ID NO.1 to SEQ ID NO.6, and by improving the screening conditions, a nucleic acid aptamer with small molecular weight, stable chemical properties, easy storage and labeling, which can bind to CD5 protein with high affinity, is screened and obtained. The aptamer is measured by surface plasmon resonance (SPR) and dot hybridization experiments to have high affinity and high specificity, and can be used in detection, diagnosis, imaging and treatment, and has broad application prospects.
Owner:HANGZHOU INSTITUTE OF MEDICAL SCIENCES CHINESE ACADEMY OF SCIENCES

Organic electroluminescent devices

Embodiments of the disclosed subject matter provide a device including a plasmonic phosphorescent organic light emitting device (PHOLED) having an anode and a cathode having a thickness of about 5-100 nm. An emissive stack is disposed between the anode and the cathode and configured to produce excitons, and having a phosphorescent first emissive layer comprising an organic phosphorescent first emissive material. The device includes an enhancement layer comprising a plasmonic material exhibiting a surface plasmon resonance that non-radiatively couples to at least the organic phosphorescent first emissive material and transfers excited state energy from the first emissive material to non-radiative modes of the plasmonic material. The device is configured to generate less than 1° C. rise in Temp for every 2.26 mW / cm2 of operating power applied to the device.
Owner:UNIVERSAL DISPLAY CORP

Automatic rivet feeding module of handheld SPR riveting device

The utility model relates to the technical field of riveting equipment, and discloses an automatic rivet feeding module of a handheld SPR (Surface Plasmon Resonance) riveting device, which is characterized in that through a positioning part on a rivet feeding body, an inverted buckle head of a fastener is inserted into a positioning hole corresponding to a rivet in a material belt for primary positioning; after the first arc-shaped flange positions one side of the punching rod and the second arc-shaped flange further positions the other side of the punching rod and the rivet cap edge, second-time positioning is completed; the posture balance of the rivet is ensured; meanwhile, the rivets continue to enter the guide part, the guide part further guides the rivets, the levelness of the rivets is guaranteed, and the rivet overturning phenomenon is effectively reduced.
Owner:GUANGZHOU DE MA WEI IND EQUIPMENT MANUFACTURE CO LTD

High-activity surface enhanced Raman scattering substrate as well as preparation method and application thereof

The invention belongs to the technical field of surface enhanced Raman spectroscopy, and particularly relates to a high-activity surface enhanced Raman scattering substrate as well as a preparation method and application thereof. Comprising the following steps: by utilizing a three-phase liquid-liquid interface self-assembly method, adding dichloromethane into an AuNPs dispersion liquid, uniformly mixing, adding a halide salt solution, uniformly mixing to form a mixed solution, then adding normal hexane into the mixed solution, standing, performing interface self-assembly until a gold nano-film is formed on a liquid surface, fishing out the gold nano-film, and drying to obtain the gold nano-film. The high-activity surface enhanced Raman scattering substrate is obtained. According to the method, the halide salt solution is innovatively introduced in the self-assembly process of the AuNPs, so that the assembly arrangement mode of the AuNPs is remarkably changed, the AuNPs are arranged more tightly, local surface plasma resonance coupling is enhanced, more hot spot areas are generated in a unit area, and the sensitivity of the self-assembly nano array SERS substrate is effectively improved.
Owner:OCEAN UNIV OF CHINA

Eagle eye bionic dynamic visual sensor and preparation method and application thereof

The invention belongs to the related technical field of neuromorphic visual sensors, and discloses an eagle-eye bionic dynamic visual sensor and a preparation method and application thereof, the visual sensor comprises a dielectric layer substrate, a functional layer and a cross array structure composed of a bottom electrode, an insulating layer and a top electrode which are arranged from bottom to top; wherein the functional layer is of a core-shell heterojunction structure formed by noble metal nanoparticles and a two-dimensional metal chalcogenide. According to the obtained core-shell heterojunction structure, an electron capture and slow release phenomenon caused by local surface plasmon resonance effect excitation and interface defects of precious metal nanoparticles is constructed on a device, and the sensor can realize an eagle-eye-imitating dynamic visual function; and the visual sensor can perform eagle-eye-imitating dynamic visual processing on image information due to a unique electronic synapse function while realizing an image optical sensing function, so that integration of sensing and preprocessing functions is realized.
Owner:HUAZHONG UNIV OF SCI & TECH

Plasma resonance enhanced microstructure of infrared photoelectric detector and preparation method

The invention provides a plasma resonance enhanced microstructure of an infrared photoelectric detector and a preparation method, and belongs to the technical field of medium-wave infrared photoelectric detectors, and the method comprises the steps: enabling incident light to irradiate downwards from the upper part of a top resonance layer when the medium-wave infrared photoelectric detector is used, and enabling the incident light to irradiate downwards from the lower part of the top resonance layer; the bottom resonance layer, the dielectric blocks and the top resonance layer form an array-arranged microstructure which can excite a plasmon mode, a surface plasmon resonance effect is triggered near the surface of the photosensitive layer through the combined action of the top resonance layer and the bottom resonance layer, the dielectric blocks are embedded in the bottom resonance layer, and the surface plasmon resonance effect is achieved. Incident light is localized in a shallower depth in a photosensitive surface, the intensity of a local electric field is enhanced, the reflection phenomenon of the photosensitive surface is reduced, the light absorption rate of the detector is improved, and the quantum efficiency of the medium-wave infrared photoelectric detector is further improved.
Owner:HANGZHOU INST FOR ADVANCED STUDY UCAS

Photoelectrocatalytic material as well as preparation method and application thereof

The invention relates to the field of photoelectrocatalytic materials, and discloses a photoelectrocatalytic material and a preparation method and application thereof.The photoelectrocatalytic material is formed by a bismuth molybdenum oxide and nickel-doped cobalt oxide heterostructure, the surface plasma resonance effect of gold nanoparticles and a conductive network of nitrogen-doped graphene and carbon quantum dots are combined, and a graded micro-nano structure is constructed; according to the present invention, the material has characteristics of high light current density, low charge transfer resistance and excellent catalytic activity and long-term stability in liquid-phase degradation and gas-phase oxidation through the built-in electric field and the optimization of the conductive network, such that the material has characteristics of high light current density and low charge transfer resistance, and can be used in liquid-phase degradation and gas-phase oxidation. The material is widely applicable to the fields of pollutant degradation, gas conversion, water photoelectrolysis and the like, and an efficient solution is provided for innovative development of a photocatalysis technology.
Owner:XINXIANG UNIV

Anti-transferrin receptor antibodies with tailored affinity

Herein is reported an anti-transferrin receptor antibody that specifically binds to human transferrin receptor and cynomolgus transferrin receptor, which comprises i) a humanized heavy chain variable domain derived from the heavy chain variable domain of SEQ ID NO: 01, and ii) a humanized light chain variable domain derived from the light chain variable domain of SEQ ID NO: 26, wherein the antibody has an off-rate for the human transferrin receptor that is equal to or less than (i.e. at most) the off-rate of the anti-transferrin receptor antibody 128.1 for the cynomolgus transferrin receptor, whereby the off-rates are determined by surface plasmon resonance, and whereby the anti-transferrin receptor antibody 128.1 has a heavy chain variable domain of SEQ ID NO: 64 and a light chain variable domain of SEQ ID NO: 65.
Owner:F HOFFMANN LA ROCHE INC

Preparation method of flexible infrared metasurface absorber based on MDM

The invention discloses a preparation method of a flexible infrared super-surface absorber based on MDM, and belongs to the field of micro-nano machining patterning. The method comprises the following steps: pretreating a polymer material; depositing a layer of bottom metal film on the pretreated substrate by adopting magnetron sputtering; a metal reflecting layer, a dielectric insulating layer and a metal surface functional layer are sequentially deposited through magnetron sputtering, a periodic nano microstructure is constructed on the surface of a flexible composite film, a nano round pit array is etched in situ on a surface metal layer of an MDM structure by using a femtosecond laser selective etching process, and an MDM laminated structure is formed. According to the invention, stable integration of the MDM structure and the flexible substrate can be realized, and meanwhile, high absorptivity and good flexibility of the device in an infrared band are ensured. The absorber prepared by the invention can generate resonance absorption on incident infrared electromagnetic waves through a surface plasmon and F-P cavity resonance coupling mechanism, and meanwhile, the characteristic size variation is changed through physical excitation, so that effective absorption and frequency regulation of the electromagnetic waves at the infrared band of 3-14 microns are realized.
Owner:BEIJING INFORMATION SCI & TECH UNIV

Bonding wire welding method based on bare chip interconnection

The invention relates to the technical field of semiconductor packaging, and discloses a bonding wire welding method based on bare chip interconnection, and the method comprises the steps: collecting and fusing acoustic response and optical reflection signals of a bonding interface in real time through a multi-mode in-situ sensing mechanism integrating acoustic resonance and surface plasmon resonance; dynamically calculating the thickness, the mechanical coupling deformation and the energy dissipation state of the intermetallic compound layer; and the ultrasonic power and the bonding force are subjected to closed-loop adjustment in combination with a model prediction control algorithm, so that the welding process is evolved along a preset optimal physical path all the time. The system comprises a multi-mode sensing welding head, a synchronous data acquisition module, a state resolving module and a self-adaptive control module. The transparent and intelligent welding process is realized, and the bonding consistency, reliability and yield of high-density interconnection are remarkably improved.
Owner:SHENZHEN TONGFANG ELECTRONGIC NEW MATERIAL CO LTD

Method and system for constructing non-reciprocal emission / absorption device with Fizeau drag effect

The invention provides a construction method and system of a non-reciprocal emission / absorption device with a Fizeau dragging effect. The construction method comprises the following steps: selecting a metal substrate, a dielectric grating and a two-dimensional material; applying a bias voltage in the x-axis direction to the two-dimensional material layer to generate a Fizeau dragging effect; the bias voltage is adjusted under TM polarization, so that the electron drift speed is close to the Fermi speed, asymmetric surface plasmon resonance is excited, and unequal emissivity and absorptivity are achieved; an adjustable singular point is generated in an angle-frequency space by adjusting the filling ratio of the grating, so that the numbers of spectral formants of emissivity and absorptivity near the singular point are different, and the wavelength integral nonreciprocity intensity is improved. The non-reciprocal heat radiation characteristic can be realized through voltage regulation and control without an external magnetic field.
Owner:SHANGHAI JIAOTONG UNIV

Optical fiber SPR sensor and preparation method thereof

The invention belongs to the technical field of optical fiber sensors, and discloses an optical fiber SPR (Surface Plasmon Resonance) sensor and a preparation method thereof. The optical fiber SPR sensor provided by the invention comprises a first optical fiber, a capillary optical fiber and a multimode optical fiber, the first optical fiber is an optical fiber capable of realizing double-path optical transmission, the surface of the capillary optical fiber is plated with a metal film, and two ends of the capillary optical fiber are respectively welded with the first optical fiber and the multimode optical fiber; an optical signal transmitted along a first path of the first optical fiber enters the inner wall of the capillary optical fiber to be totally reflected, and interacts with the metal film to generate SPR (Surface Plasmon Resonance) which is received by the multimode optical fiber for external refractive index sensing; and the optical signal transmitted along the second path of the first optical fiber enters the air cavity of the capillary optical fiber and is received by the multimode optical fiber after passing through the air cavity, and the two paths of optical signals at the output end form Mach-Zehnder interference for external temperature sensing. According to the invention, external refractive index and temperature change can be measured at the same time, cross-talk can be avoided, and high sensitivity is achieved.
Owner:JIANGSU UNIV OF SCI & TECH

Method for enhancing animal virus detection sensitivity by surface modification of optical fiber SPR (surface plasmon resonance) probe

The invention relates to the technical field of virus detection, in particular to a method for enhancing animal virus detection sensitivity through optical fiber SPR probe surface modification, which comprises the following steps: S1, optical fiber SPR probe surface pretreatment: obtaining a hydroxylated surface; s2, gradient nanostructure modification: forming a gradient aperture surface topological structure; s3, carboxyl functionalization: immersing the substrate into a 3-aminopropyltriethoxysilane / methacrylic acid mixed solution, and constructing a carboxyl activation layer on the surface; s4, fixation of the aptamer: realizing directional fixation of the aptamer through EDC / NHS mediated carboxyl-amino coupling reaction; s5, non-specific site closing: carrying out cross-linking closing on the non-binding sites by adopting a thioacetamide / polydopamine composite solution; s6, virus detection: acquiring the surface refractive index variation through a phase modulation type SPR detection system; according to the invention, accurate fitting and quantitative correction of virus concentration are realized, and the stability and accuracy of detection are improved.
Owner:ZHEJIANG SHUREN UNIV

Narrowband photoelectric detector based on local plasma enhanced perovskite and preparation method

The invention discloses a perovskite narrow-band photoelectric detector based on local plasma enhancement and a preparation method thereof, and the perovskite narrow-band photoelectric detector utilizes specially-made metal nanoparticles to accurately adjust a local surface plasma resonance band of the perovskite narrow-band photoelectric detector, thereby achieving the purpose of overlapping with a perovskite target narrow-band response range. Therefore, penetrating long-wavelength incident photons and an electromagnetic field around the metal nanoparticles generate strong coupling interaction, light absorption is effectively improved through a near-field enhancement induction excitation effect, light current is remarkably enhanced, a local surface plasmon resonance band is regulated and controlled, harmonious enhancement of a detection wave band is achieved, and the detection sensitivity is improved. And the detection performance regulation and control enhancement in the spectral response range of the photoelectric detector is further realized.
Owner:NORTHEAST GASOLINEEUM UNIV

Tetrahydro-beta-carboline compound as well as preparation method and application thereof

The invention discloses a tetrahydro-beta-carboline compound as well as a preparation method and application thereof. The tetrahydro-beta-carboline compound is shown as a formula P. The tetrahydro-beta-carboline compound has good RANKL inhibitory activity, the preparation method is simple, raw materials are easy to obtain, and the yield is high. The inhibition activity of the compound on generation of RANKL-induced osteoclasts is determined through a tartrate acid phosphatase (TRAP) staining experiment, it is determined through a surface plasmon resonance (SPR) that the compound has high combining capacity with RANKL protein, and the compound can be used for preparing drugs for preventing and / or treating diseases caused by abnormal osteoclast activity. # imgabs0 #
Owner:SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES +1

Reflective solid crystal adhesive material based on nanoparticle dispersion technology, preparation process and application

The invention relates to the technical field of solid crystal glue materials, in particular to a reflective solid crystal glue material based on a nanoparticle dispersion technology, a preparation process and application. The coating comprises a resin matrix, a nanometer functional filler and an auxiliary agent system, wherein the resin matrix at least comprises epoxy resin, cyanate ester resin and benzoxazine resin; the nano functional filler is one of a nano particle material or a nano filler; through the synergistic effect of the surface-modified zinc oxide nanoparticles and the surface-modified cerium oxide nanoparticles and in combination with the total reflection characteristic of the titanium dioxide coated glass beads, an efficient reflection-refraction synergistic enhancement system is constructed; the plasma resonance effect of the surface-modified cerium oxide nanoparticles is matched with the high-refractive-index zinc oxide nanoparticles, so that the initial luminous flux of an LED is improved by 18%-22% compared with that of traditional solid crystal glue, the light utilization rate is improved by 20%-25%, the six-surface luminous potential of a chip is excavated, and therefore the quality of the solid crystal glue is improved.
Owner:LIANYUNGANG ZHAOHUA TECH

Surface plasma resonance hydrogen sensor based on Ag / PDMS / Pt-WO3 multilayer structure

The invention discloses a surface plasmon resonance (SPR) hydrogen sensor based on an Ag / PDMS / Pt-WO3 multilayer structure. The SPR hydrogen sensor is characterized by comprising a halogen lamp light source, two sections of multimode optical fibers, a spectrometer and an SPR hydrogen sensing head, wherein the SPR hydrogen sensing head is composed of a different-core structure formed by multimode-single-mode-multimode optical fibers, a silver film, PDMS (polydimethylsiloxane) and Pt-WO3 (platinum-tungsten trioxide). The SPR hydrogen sensor based on the Ag / PDMS / Pt-WO3 multi-layer structure, which is simple to prepare, high in sensitivity and capable of being repeatedly used for a long time, is provided aiming at the defects that an existing optical fiber SPR hydrogen sensor is low in sensitivity and complex in device manufacturing, and PdH is changed from an alpha phase to a beta phase when Pd is used as a hydrogen sensitive material, so that the use of the device is influenced, and the like. When the hydrogen concentration is increased, the Pt-WO3 reacts with the hydrogen to generate heat, so that the refractive index of the PDMS film is changed, the SPR resonance spectrum is moved, and the hydrogen concentration is obtained by observing the offset of the PDMS film. The high refractive index sensitivity of SPR is brought into full play by utilizing the high refractive index change of PDMS, so that high-precision detection of hydrogen leakage is realized.
Owner:CHINA JILIANG UNIV

Surface plasmon resonance radiation cooling-heat conduction-liquid film evaporation coupling heat dissipation multi-layer co-construction micro-nano structure and manufacturing method and application thereof

The invention discloses a surface plasmon resonance radiation cooling-heat conduction-liquid film evaporation coupling heat dissipation multi-layer co-construction micro-nano structure and a manufacturing method and application thereof, and belongs to the technical field of micro-nano manufacturing and functional structure surfaces, and the multi-layer co-construction micro-nano structure is composed of three layers of structures; the bottom layer structure is a substrate; the top of the bottom layer structure is a near-infrared wavelength scale grating structure; the middle-layer structure is a high-thermal-conductivity diamond film and covers and fills the bottom-layer structure; the top of the middle-layer structure is of a lyophilic micro-nano structure; the top layer structure is a silicon dioxide film. Radiation cooling, efficient heat conduction and liquid film evaporation / boiling phase change heat transfer are coupled, the heat transfer and heat dissipation level is greatly improved, additional external energy input is not needed, and positive significance is achieved for research and development of a novel high-performance and zero-energy-consumption radiator, promotion of development of a high-heat-flow-density advanced system and improvement of the ecological environment.
Owner:NANJING UNIV OF AERONAUTICS & ASTRONAUTICS

Functionalized glass for sers detection and method of making the same

The application relates to a functionalized glass for SERS detection and a preparation method thereof, characterized by the following steps: a. tetraethyl orthosilicate and oxalic acid are mixed into a 0.02-0.10 moL / L sol in anhydrous ethanol according to a molar ratio of 1:2-5, a stabilizer with a volume of 5-50% is added, and then the mixture is stirred and transferred into a four-necked flask; b. after being heated and stirred for 12-16 hours, an anhydrous ethanol emulsion of polystyrene small balls with a mass fraction of 5-20% and a volume of 6-18% is added; c. an anhydrous ethanol solution of a surfactant P123 with a total mass of 2-8% and a weight concentration of 3-8% is added, and then the mixture is stirred and aged; d. a wet film is prepared on a glass substrate, and then the wet film is dried and kept warm; (2) a nano-silver particle dispersion liquid with a concentration of 5-25 mg / mL is prepared; and (3) the glass substrate prepared in the step d is coated with the nano-silver particle dispersion liquid and dried. The application has the advantages of simple process and low cost; the surface of the porous structure silica nano-particles has a large number of nanoscale gap structures, which is beneficial to obtaining an enhanced silver nano-particle surface plasmon resonance electromagnetic field, and greatly enhances the Raman signal of the adsorbed molecules.
Owner:CNBM RESEARCH INSTITUTE FOR ADVANCED GLASS MATERIALS GROUP CO LTD

Surface plasma imaging method and device

The invention provides a surface plasma imaging method and a surface plasma imaging device, which are used for imaging surface plasma signals caused by interaction of biomolecules. More specifically, the invention provides a method and a device capable of imaging a surface plasmon resonance mode in a frequency domain through tiny change by comparing the light intensity in two sections of surface plasmon frequency domains.
Owner:ACAD SINICA