720 results about "Surface plasmonic resonance" patented technology

A system for energy upconversion and / or down conversion and a system for producing a photostimulated reaction in a medium. These systems include 1) a nanoparticle configured, upon exposure to a first wavelength λ1 of radiation, to generate a second wavelength λ2 of radiation having a higher energy than the first wavelength λ1 and 2) a metallic structure disposed in relation to the nanoparticle. A physical characteristic of the metallic structure is set to a value where a surface plasmon resonance in the metallic structure resonates at a frequency which provides a spectral overlap with either the first wavelength λ1 or the second wavelength λ2, or with both λ1 and λ2. The system for producing a photostimulated reaction in a medium includes a receptor disposed in the medium in proximity to the nanoparticle which, upon activation by the second wavelength λ2, generates the photostimulated reaction.

Methods of binding and detecting a microorganism on a solid substrate. The microorganism is bound on a solid substrate covalently bound to a capture agent having a saccharide moiety. A lectin capable of binding to the microorganism and the saccharide moiety of the capture agent is added to the sample to bind the microorganism on the solid substrate. Further provided are biosensor devices, such as a quartz crystal microbalance (QCM) device or a surface plasmon resonance (SPR) device, that incorporate the solid substrate for the detection of microorganisms.

The present invention is directed to photostable sunscreen and / or artificial tanning compositions including quantum dot nanocrystals of a material selected from semiconductor nanocrystals, modified semiconductor nanocrystals, multicomponent semiconductor / semiconductor nanocrystals, and hybrid semiconductor / metal nanocrystals, the quantum dot nanocrystals having an absorption band gap occurring at wavelengths higher than 400 nm whereby the quantum dot nanocrystals have substantial broadband absorption properties of ultraviolet light at wavelengths across the range of both UV-A (320-400 nm) and UV-B (280-320 nm), and a dermatologically acceptable carrier for the quantum dot nanocrystals. The present invention is further directed to photostable sunscreen and / or artificial tanning compositions including a material selected from metallic nanocrystals, multicomponent metal / metal nanocrystals, and alloyed metal nanocrystals, the metallic material having a surface plasmon resonance occurring sufficiently into the visible or infrared spectral region whereby broad absorption features due to electronic transitions, the broad absorption features located at higher energies, provide substantial broadband absorption properties of ultraviolet light at wavelengths across the range of both UV-A (320-400 nm) and UV-B (280-320 nm), and a dermatologically acceptable carrier for the metallic material.

A display system having a non-absorbing and reflective color filtering array and a reflector to improve light utilization efficiency. One implementation of the color filtering array uses a surface plasmon filter having two symmetric metal-dielectric interfaces coupled with each other to produce a transmission optical wave at a surface plasmon resonance wavelength at one interface from a p-polarized input beam on the other interface. Another implementation of the color filtering array uses a metal-film interference filter having two dielectric layers and three metallic films.

A flow imaging system is used to implement surface plasmon resonance (SPR) detection to study bio-molecular interactions. The flow imaging system is used to capture SPR absorption spectra of large numbers of objects, where each object includes both a metal film capable of exhibiting SPR, and detecting molecules. Analyte molecules are added to a solution of such objects, and the result is introduced into the flow imaging system which collects full SPR spectral data from individual objects. The objects can be nanoparticles or larger particles that support metal island films. The SPR spectral data can be used to determine specificity, kinetics, affinity, and concentration with respect to the interactions between the detecting molecules and the analyte molecules.

A system for energy upconversion and / or down conversion and a system for producing a photostimulated reaction in a medium. These systems include 1) a nanoparticle configured, upon exposure to a first wavelength λ1 of radiation, to generate a second wavelength λ2 of radiation having a higher energy than the first wavelength λ1 and 2) a metallic structure disposed in relation to the nanoparticle. A physical characteristic of the metallic structure is set to a value where a surface plasmon resonance in the metallic structure resonates at a frequency which provides a spectral overlap with either the first wavelength λ1 or the second wavelength λ2, or with both λ1 and λ2. The system for producing a photostimulated reaction in a medium includes a receptor disposed in the medium in proximity to the nanoparticle which, upon activation by the second wavelength λ2, generates the photostimulated reaction.

A method of forming a fine pattern begins with providing a c-plane hexagonal semiconductor crystal. A mask having a predetermined pattern is formed on the semiconductor crystal. The semiconductor crystal is dry-etched by using the mask to form a first fine pattern on the semiconductor crystal. The semiconductor crystal including the first fine pattern is wet-etched to expand the first fine pattern in a horizontal direction to form a second fine pattern. The second fine pattern obtained in the wet-etching the semiconductor crystal has a bottom surface and a sidewall that have unique crystal planes, respectively. The present fine-pattern forming process can be advantageously applied to a semiconductor light emitting device, particularly, to a phonic crystal structure required to have fine patterns or a structure using a surface plasmon resonance principle.

Arrays are provided for multiplexed evanescent scanning by allowing for high-contrast Surface Plasmon Resonance images thereof. The arrays target features are typically biopolymeric in nature, though they may be any sort of chemical or ligand. The type of scanning is such that there is no need for probe labeling. As no labeling is required, a broader range of applications than otherwise possible is facilitated. In the subject arrays, target features are set upon a noble metal film deposited on a substrate. Interfeature areas are adapted to trap, divert and / or bleed-away light so that light directed through the substrate will not be reflected by those areas and interfere with evanescent scanning of the reflective areas upon which intended target features are provided. Geometric and materials-based light attenuating features are contemplated. Arrays as described, hardware and software as required for reading such arrays, and associated methodology are covered.

A display device includes a display panel, a backlight unit and a color conversion layer. The color conversion layer includes light emitting particles and metal particles. The light emitting particles are configured to receive a first light and to generate a second light having a wavelength different from the first light. The metal particles are configured to receive the first light or the second light and to cause a surface plasmon resonance.

An apparatus utilizes miniaturized surface plasmon resonance (SPR) and ion-selective self-assembled monolayer (SAM) and hydrogel chemistry to measure metal ion concentrations in liquids. The SPR optical system is packaged in a compact and cost-effective form factor. An electronic circuit drives the optical system. The SPR system utilizes an optical window that is coated with the SAM layer or hydrogel material. The SAM layer and hydrogel materials are highly selective to a specific metal ion of interest. The miniaturized SPR sensor is situated in an optical-fluidic cell or an optical-fluidic manifold with the SAM layer or hydrogel material in contact with the liquid. Metal ions selectively attach to the SAM layer or hydrogel material, thereby affecting the SPR signal. Changes in the SPR signal are used to accurately determine the metal ion concentration in the liquid. The liquids may be either static or dynamic.

The methods and applications of a surface plasmon resonance-enhanced marking technique are disclosed. The technique uses surface plasmon resonance (SPR) excited nanoparticles and a surface plasmon resonance source in nonlinear interactions with nearby chemical substances and medium for marking purposes. The SPR-enhanced absorption and fluorescence rates of chemical substances or medium and nonlinearity of SPR interactions with chemical substances or medium make the proposed method suitable for marking fragile materials including biomaterials, such as writing on thin plastic foils or DNA-protein crosslinking. The marking method can also be applied to a three-dimensional recording and read out information system with subwavelength resolutions, coding information of secrete documents, drug delivery, tissue surgery, tattoo writing or removal, photodynamic therapy, cosmetic and dermatological treatment.

The invention discloses a manufacturing method of a tunable triangular metal nano particle array structure. The method comprises the following steps: (1) selecting a substrate with a suitable model according to the requirement of transmission wavelength, and carrying out cleaning and hydrophiling treatment on the substrate; (2) evenly self-assembling a layer of nano spheres on the surface of the substrate; (3) etching the manufactured self-assembling nano sphere layer by using a reaction ion etcher (RIE) process to change the size of gaps between adjacent nano spheres; (4) self-assembling etched nano spheres to serve as a mould, and filling metals in gaps between adjacent nano spheres; and (5) removing the nano sphere self-assembling layer by using a Lift off process to obtain an array chip in a metal nano structure. The manufactured chip in the metal nano structure has controllable optical property, can be applied to fields such as local surface plasma resonance (LSPR) sensing, surface enhanced Raman spectroscopy (SERS) and the like, and can realize rapid detection of biologic and chemical molecules.

The invention relates to a reflection type color filter, comprising pixel arrays with three colors. A pixel structure with each color comprises a substrate, a metal layer positioned on the substrate, a dielectric layer positioned on the metal layer and a two-dimensional metal grating layer positioned on the dielectric layer, wherein the thickness of the metal layer is greater than the skin depth of visible light in the metal layer, and the surface plasma resonance frequency of the pixel structure is the frequency of the complementary color of the pixel color. The reflection type color filter performs optical filtering based on the subtractive theorem, and has the characteristics of high optical energy utilization rate, low angle sensitivity and insensitivity to polarization.

A fluid dispenser for surface plasmon resonance (SPR) assay apparatus includes a first pipette device on a first pipette head, and a second pipette device on a second pipette head. In a standby state, the first pipette head is set in an upper position, a coil spring and a stopper set the second pipette head together with the first pipette head, and locate the second pipette head in a high position. While the first and second pipette devices are in an aspirating position, a driving mechanism sets the first pipette head in a lower position. A blocking mechanism sets the second pipette head in a high position against the coil spring. First, third and fifth pipette tips is positioned lower than second, fourth and sixth pipette tips, to access a well. The first to sixth pipette tips, while in an assay position, are equally lowered.

The invention belongs to the technical field of detection and particularly relates to lead ion colorimetric detection probes and an application method thereof. In the method, glutathione modified gold nanoparticles are used as colorimetric probes, glutathione combines with gold nanoparticles by utilizing sulfydryl groups of the glutathione for coordination to form a stable structure of which the surface contains two free carboxyl radicals. In the process of detection, the carboxyl radicals can coordinate with heavy metal ions; and by utilizing the property of surface plasma resonance of the gold nanoparticles, the existence of the heavy metal ion Pb2+ in aqueous solution can be indicated by the color change of the solution. The lead ion colorimetric detection probes have the advantages that: the sensitivity and selectivity are high; in-situ quick detection can be realized without large-size instruments; the detection results are visual and can be observed by naked eyes; the operation is simple and the cost is low; and the used solvents and the operation processes have no toxic or side effects.

A fiber-optic surface plasmon resonance sensor may include an optical fiber and a surface plasmon excitation layer. The optical fiber may include a core, a cladding surrounding the core, and a depression. The surface plasmon excitation layer may include a first excitation layer, a second excitation layer and an optical waveguide layer between the first excitation layer and the second excitation layer. Incident light incident through the core may be coupled to the surface plasmon excitation layer at a specific angle of incidence and wavelength satisfying the surface plasmon resonance condition. Depending on the polarizing direction of the incident light, an s-polarized component may be coupled to the guided-wave mode in the optical waveguide layer constituting the surface plasmon excitation layer.

The invention provides a sensor for nano gold particles and a preparation method thereof. The end surface of a multi-core optical fiber is of a conical-platform structure; a total-reflection film is plated on the surface of the conical platform; the nano gold particles which are distributed regularly are fixed on the end surface of the optical fiber plated with the total-reflection film; exciting light is injected into one fiber core of the multi-core optical fiber, is reflected to the end surface of the optical fiber at the film-plated position of the conical platform and generates total internal reflection on the end surface of the optical fiber, and a generated evanescent field excites a localized surface plasmon resonance effect of the nano gold particles; the reflected light is collected by the fiber core symmetrical to the fiber core injected with the exciting light, and the change of the physical quantity of external substances is sensed by the spectrum of the reflecting light. The sensor and the preparation method have the advantages that the multi-core optical fiber, a self-assembly technology of a near-field optical tweezer and the localized surface plasmon resonance effect of the nano gold particles are combined, and the near-field optical tweezer of the multi-core optical fiber can be utilized for capturing the nano gold particles, so that the optical self-assembly and regular distribution is carried out on the nano gold particles according to the distribution rule of the capturing areas; the structure is simple, the volume is smaller and the repeatability is high.

The present disclosure relates to a device for measuring surface plasmon resonance and fluorescence of a sample, a system for determining the rate of catalytic activity of an enzyme, a method of determining the rate of catalytic activity of an enzyme, and a method of measuring the adsorption and reactivity of a substance, all of which use SPR and SPEF methods simultaneously. This invention also relates generally to systems and methods for measuring diffusion and reactivity of macromolecules on a surface.

The invention is a surface plasmon resonance (SPR) sensor to determine the presence and quantity of biological or chemical entities in an analyte. The sensor comprises a metal periodic structure deposited as a thin layer of a noble metal, comprising a one dimensional array of nanoslits or a two dimensional array of nanoholes on a transparent dielectric substrate, a nm-thick layer of transparent dielectric protection layer on top of the metal periodic structure and a functionalization layer, which acts as a binding layer to biological or biochemical entities in an analyte that is in contact with the functionaliztion layer.

The present invention provides methods and compositions for amplifying the detection signal in surface plasmon resonance (SPR)-based flow systems. The signal amplification methods comprise the use of well established marker systems that provide a precipitate. The marker systems include, for example, enzyme and nucleation systems. Enzymes suitable for use as a marker system include peroxidases and phosphatases. The amplification system is useful in any SPR-based detection system including microfluidic systems, e.g., “lab on a chip” systems and the like. The methods can comprise any SPR-based assay format, including typical immunoassay formats. The immunoassay formats can include competitive and sandwich assays. Analyte capture agents can include antibodies, lectins, carbohydrates, polynucleotides, receptor proteins, and the like.

The invention relates to a spectral method capable of exciting surface-enhanced Raman spectroscopy (SERS) in a long range surface plasmon mode. The method comprises the following steps of: constructing a buffer layer, a metal layer and a protective layer on the bottom surface of a prism to form a long range surface plasmon resonance (LRSPR) device; placing the LRSPR device with multilayer structure under the irradiation of a laser source, and adjusting the incident angle of the laser source to an LRSPR angle; and in a specific incident direction, generating the LRSPR, so that the electric magnetic field on the surface of a metal is enhanced, and the excitation process of the surface-enhanced Raman spectroscopy of a detected object of a deeper area in a sample layer is completed. Because the long range effect has deeper penetrating effect, the construction of the protective layer on the surface of the metal layer becomes possible. The transduction membrane made of chemically inert gold or platinum is changed into a silver membrane with lower cost, oxidation resistance and better enhancing effect. The LRSPR-mechanism-based SERS detection method has great significance.

Coating compositions containing resins with dispersed nanoparticle precursors and methods for using said coatings as visual indicators of thermal and impact damage. The nanoparticle precursor / resin system reduces the nanoparticle precursor to its nanoparticle state when subjected to heat and / or physically impacted. The nanoparticles formed impart a color upon the coating at the point of exposure due to surface plasmon resonance. Microencapsulated leuco dyes are utilized to impart color when the coating is struck. The dye within the microcapsule is released as the microcapsule wall bursts or melts. Solubillizing agents can be utilized to improve the solubility of the nanoparticle precursor in the resin.

A method of particle detection includes optically trapping a single particle having an averaged linear dimension of between 0.10 microns and 50 microns in a focal region optical trap formed from a trap visible to near-infrared wavelength. The trap is proximal to a substrate having a discontinuous metal coating so as to exploit a surface plasmon resonance generated electric field caused by irradiation of the metal coating. The single particle is then exposed to an interrogation wavelength to yield scattering spectrum relating to the particle. A particle identification digital database containing scattering spectra from a variety of different single particles that vary in spectral features facilitates identification of unknown spectra. A microfluidic cell is detailed to facilitate the automated scanning of numerous particles from a sample.

Provided are novel nanostructures comprising hollow nanospheres (HGNs) and nanotubes for use as chemical sensors, molecular specific photothermal coupling agents, and photothermal ablation compounds. The nanostructures can be used in electromagnetic radiation-induced phototherapy for treatment of cancer and other disorders. The nanostructures can also be used as a sensor that detects molecules. The nanostructures are of particular use in the fields of clinical diagnosis, clinical therapy, clinical treatment, and clinical evaluation of various diseases and disorders, manufacture of compositions for use in the treatment of various diseases and disorders, for use in molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof. The hollow gold nanospheres have a unique combination of spherical shape, small size, and strong, tunable, and narrow surface plasmon resonance absorption covering the entire visible to near IR region.

A sensor chip assembly for use in a sensor capable of Surface Plasmon Resonance (SPR) and gravimetric sensing. The assembly comprising a transparent piezoelectric substrate (I) having a first surface and a second surface opposite to the first surface. The assembly also comprising first and second thin film metal electrodes (2,3) respectively provided on the first and second surfaces of the substrate (1). The second thin film metal electrode (3) being position on the second surface of the substrate (1) such that a light beam is capable of being transmitted through the second surface of the substrate and reflected from the first thin film metal electrode. The assembly also comprising an attenuated total reflection (ATR) coupler (11) disposed adjacent to the second thin film metal electrode (3).

The invention belongs to a supported two-dimensional layered molybdenum sulfide composite material and discloses a noble metal (Ag, Au)-supported composite nano-catalytic material and its application in catalytic reduction of p-nitrophenol. The two-step synthetic technology is adopted in the invention. Firstly, molybdenum sulfide nanosheet with a porous ultrathin structure is synthesized by a hydrothermal method; then, by an ultraviolet reduction technology, noble metal nanoparticles are supported onto the surface of the two-dimensional layered compound molybdenum sulfide with a sandwich structure, and agglomeration phenomenon during the noble metal preparation process can be effectively avoided by the combination of nano confinement growth effects; and finally, noble metal nanoparticles with uniform size distribution are obtained. According to the supported catalyst system, the metal catalytic active center and a carrier together form a catalyst due to localized surface plasma resonance effect of noble metal active ingredients and synergistic effect between noble metal active ingredients and the carrier.

An ultrathin plasmonic subtractive color filter in one embodiment includes a transparent substrate and an ultrathin nano-patterned film formed on the substrate. A plurality of elongated parallel nanoslits is formed through the film defining a nanograting. The nanoslits may be spaced apart at a pitch selected to transmit a wavelength of light. The film is formed of a material having a thickness selected, such that when illuminated by incident light, surface plasmon resonances are excited at top and bottom surfaces of the film which interact and couple to form hybrid plasmon modes. The film changes between colored and transparent states when alternatingly illuminated with TM-polarized light or TE-polarized light, respectively. In one configuration, an array of nanogratings may be disposed on the substrate to form a transparent display system.

A new hybrid nanoparticle, i.e., a nanorice particle, which combines the intense local fields of nanorods with the highly tunable plasmon resonances of nanoshells, is described herein. This geometry possesses far greater structural tunability than previous nanoparticle geometries, along with much larger local field enhancements and far greater sensitivity as a surface plasmon resonance (SPR) nanosensor than presently known dielectric-conductive material nanostructures. In an embodiment, a nanoparticle comprises a prolate spheroid-shaped core having a first aspect ratio. The nanoparticle also comprises at least one conductive shell surrounding said prolate spheroid-shaped core. The nanoparticle has a surface plasmon resonance sensitivity of at least 600 nm RIU−1. Methods of making the disclosed nanorice particles are also described herein.

The invention discloses a digital holographic microscopic imaging method based on surface plasma resonance and a microscope. In the microscopic imaging method, a linear polarization laser beam is expanded and collimated, and then is split into two beams, wherein one is a reference beam, the other enters a prism and is reflected by the prism surface provided with a metallic film to be an object beam; a sample to be tested is placed on the prism surface plated with the metallic film; after passing a combiner, the object beam and the reference beam enter a camera head to obtain a hologram and simultaneously obtain the strength allocation plan and phase allocation plan on the surface of the sample to be tested by a digital holographic reconstruction algorithm. The invention provides larger flexibility for selecting an incident angle, thereby having greater superiority. The surface image of a cell film, which is displayed by the phase microscopic image and the strength microscopic image obtained from the hologram, can not be obtained by the traditional microscope, therefore, the microscope of the invention has wide application prospect.

Provided is an SPR sensor which can achieve compaction and multichannel detection by simple configuration at a low cost. The SPR sensor comprises an optical path, and detection areas on the side surface thereof formed by laminating metal layers formed to cause surface plasmon resonance phenomenon. The SPR sensor is characterized in that two or more detection areas are formed for one optical path, a dielectric constant regulation layer is further laminated in at least one of the two or more detection areas, dielectric constant is regulated to have a different surface plasmon resonance in each detection area, and a dielectric constant regulation layer laminated in the at least one of the two or more detection areas functions as a layer exhibiting sensitivity to an object to be detected.