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323 results about "Leuco dye" patented technology

A leuco dye (from the Greek λευκός leukos: white ) is a dye which can switch between two chemical forms; one of which is colorless. Reversible transformations can be caused by heat, light or pH; resulting in examples of thermochromism, photochromism and halochromism respectively. Irreversible transformations typically involve reduction or oxidation. The colorless form is sometimes referred to as the leuco form.

Preparation of prodrugs for selective drug delivery

Synthesis of a chemical compound having the formula A-B-C that may serve for applications such as drug delivery where A is a chemiluminescent, moiety, B is a photochromic moiety, and C is a biologically active moiety where A-B-C may serve as a prodrug. Novel synthetic methods of the present invention to form the prodrug comprised the steps of (1) forming a benzophenone, (2) forming a diaryl ethylene, (3) attaching a phthalimide moiety to at least one of the aryl groups of the ethylene to form a phthalimide-ethylene conjugate, (4) condensing two ethylene-phthalimide conjugates to form a phthalimide-pentadiene conjugate, (5) converting the phthalimide to the phthalhydrazide by reaction with hydrazine to form a carrier compound according to the present invention, and (6) reacting the carrier compound with an nucleophilic moiety of the drug to form the corresponding prodrug. Alternatively the carrier can be prepared by using the halo-substituted diaryl ethylene to make the corresponding cationic leuco dye-like compound with known methods. The cationic compound then is protected by reacting with a nucleophile and coupled with the aminophathalimide by palladium-catalyzed amination to form the protected phthalimide-pentadiene conjugate. The latter is refluxed with hydrazine to convert its phthalimide to the phthalhydrazide and acidified to give the carrier. An additional aspect of the present invention relates to the use of these compounds as antiviral agents for the treatment of viral infections such as HIV and as anticancer agents for the treatment of cancers such as bowel, lung, and breast cancer.
Owner:LUMINIDE

Thermal initiator system using leuco dyes and polyhalogene compounds

The present invention relates to IR-sensitive compositions containing an initator system comprising:
    • (a) at least one compound capable of absorbing IR radiation selected from triarylamine dyes, thiazolium dyes, indolium dyes, oxazolium dyes, cyanine dyes, polyaniline dyes, polypyrrole dyes, polythiophene dyes and phthalocyanine pigments
    • (b) at least one compound capable of producing radicals selected from polyhaloalkyl-substituted compounds
    • (c) at least one polycarboxylic acid represented by the following formula I
wherein Y is selected from the group consisting of O, S and NR7, each of R4, R5 and R6 is independently selected from the group consisting of hydrogen, C1-C4 alkyl, aryl which is optionally substituted, —COOH and NR8CH2COOH, R7 is selected from the group consisting of hydrogen, C1-C6 alkyl, —CH2CH2OH, and C1-C5 alkyl substituted with -COOH, R8 is selected from the group consisting of —CH2COOH, —CH2OH and —(CH2)2N(CH2COOH)2 and r is 0, 1, 2 or 3 with the proviso that at least one of R4, R5, R6, R7 and R8 comprises a —COOH group or salts thereof, and
  • (d) at least one leuco dye, wherein the following inequation is met:
  • oxa<redb+1.6eV
    with oxa=oxidation potential of component (a) in eV redb=reduction potential of component (b) in eV
    These compositions are inter alia extraordinarily suitable for the manufacture of printing plates.
    Owner:KODAK POLYCHROME GRAPHICS

    Irreversible thermally induced decoloring printing ink and preparation method thereof

    InactiveCN102558952AGood writing propertiesNo natural fadingInksTenebresent compositionsTemperature controlOrganic solvent
    The invention relates to printing ink and a preparation thereof and aims to provide irreversible thermally induced decoloring printing ink and a preparation method thereof. The method comprises the following steps: adding a color-developing agent, a solubilizing agent, leuco dye, a lubricating agent, a tackifier, a filling agent and a crosslinking agent sequentially in an organic solvent according to the mass ratio of the specified components; adding the next component after stirring and dissolving the previous component; and finally stirring and dissolving to obtain the irreversible thermally induced decoloring printing ink. The printing ink can develop color at a low temperature, decolor after being heated and still maintain colorless after being cooled, so the function of decoloration control can be realized through temperature control, decoloration can be controlled in the aspects of ground pattern design of various embroideries and design and marks of various clothing, shoes and hats, shoe making and the like, and the manual elimination procedure of eliminating various marks is omitted in the production process of the products. The irreversible thermally induced decoloring printing ink is used for printing so as to eliminate printing writing controllably and realize recycling of paper.
    Owner:ZHEJIANG UNIV
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