2991results about "Spectrum investigation" patented technology

Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.

Methods and systems for monitoring a plurality of different optical signals from a single source of such signals, where each such different optical signal is spatially separated from other such signals and directed to different detectors or locations upon a single detector, which direction is generally accomplished through the use of a small numberof optical components and/or manipulations.

An apparatus and method to determine a property of a substrate by measuring, in the pupil plane of a high numerical aperture lens, an angle-resolved spectrum as a result of radiation being reflected off the substrate. The property may be angle and wavelength dependent. The radiation that is reflected off the substrate is radially polarized.

A wireless capsule as a disease diagnosis tool in vivo can be introduced into a biological body by a native and/or artificial open, or endoscope, or an injection. The information obtained from a micro-spectrometer, and/or an imaging system, or a micro-biosensor, all of which are built-in a wireless capsule, can be transmitted to the outside of the biological body for medical diagnoses. In addition, a real-time specimen collection device is integrated with the diagnostic system for the in-depth in vitro analysis

A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target.

The color image sensor generates a color image signal representing a subject and includes an optical substrate and a light sensor. The optical substrate includes spatially-separated imaging elements. Each of the imaging elements is configured to image light of a respective color. The light sensor includes regions of sensor elements disposed opposite respective ones of the imaging elements. The sensor elements in each of the regions are operable to generate a component of the color image signal in response to the light of the respective color incident on them.

The present invention provides a hyperspectral imaging system which demonstrates changes in tissue oxygen delivery, extraction and saturation during shock and resuscitation including an imaging apparatus for performing real-time or near real-time assessment and monitoring of shock, including hemorrhagic, hypovolemic, cardiogenic, neurogenic, septic or burn shock. The information provided by the hyperspectral measurement can deliver physiologic measurements that support early detection of shock and also provide information about likely outcomes.

Color calibration of color image rendering devices, such as large color displays, which operate by either projection or emission of images, utilize internal color measurement instrument or external color measurement modules locatable on a wall or speaker. A dual use camera is provided for a portable or laptop computer, or a cellular phone, handset, personal digital assistant or other handheld device with a digital camera, in which one of the camera or a display is movable with respect to the other to enable the camera in a first mode to capture images of the display for enabling calibration of the display, and in a second mode for capturing image other than of the display. The displays may represent rendering devices for enabling virtual proofing in a network, or may be part of stand-alone systems and apparatuses for color calibration. Improved calibration is also provided for sensing and correcting for non-uniformities of rendering devices, such as color displays, printer, presses, or other color image rendering device.

A color measuring sensor assembly includes an optical filter such as a linear variable filter, and an optical detector array positioned directly opposite from the optical filter a predetermined distance. A plurality of lenses, such as gradient index rods or microlens arrays, are disposed between the optical filter and the detector array such that light beams propagating through the lenses from the optical filter to the detector array project an upright, noninverted image of the optical filter onto a photosensitive surface of the detector array. The color measuring sensor assembly can be incorporated with other standard components into a spectrometer device such as a portable calorimeter having a compact and rugged construction suitable for use in the field.

Exemplary apparatus and process can be provided for imaging information associated with at least one portion of a sample. For example, (i) at least two first different wavelengths of at least one first electro-magnetic radiation can be provided within a first wavelength range provided on the portion of the sample so as to determine at least one first transverse location of the portion, and (ii) at least two second different wavelengths of at least one second electro-magnetic radiation are provided within a second wavelength range provided on the portion so as to determine at least one second transverse location of the portion. The first and second ranges can east partially overlap on the portion. Further, a relative phase between at least one third electro-magnetic radiation electro-magnetic radiation being returned from the sample and at least one fourth electro-magnetic radiation returned from a reference can be obtained to determine a relative depth location of the portion. First information of the portion based on the first transverse location and the relative depth location, and second information of the portion based on the second transverse location and the relative depth location can be obtained. The imaging information may include the first and second information.

Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains that direct excitation radiation to and emitted signals from such arrays and image the signals onto detector arrays, from which such signals may be subjected to additional processing.

A system and method of drilling and/or perforating uses a laser beam to remove material, such as to perforate the casing, cement and formation or drill a well bore. The system and method can further or alternately encompass material analysis that can be performed without removing the material from the well bore. The analysis can be performed apart from or in connection with drilling operations and/or perforating the casing, cement and formation. The analysis can be used in a feed back loop to adjust material removal, adjust material analysis, determine the location of future material removal, and for other uses.

A method for measuring overlay in a sample includes obtaining an image of an overlay target that includes a series of grating stacks each having an upper and lower grating, each grating stack having a unique offset between its upper and lower grating. The image is obtained with a set of illumination and collection optics where the numerical aperture of the collection optics is larger than the numerical aperture of the illumination optics and with the numerical apertures of the illumination and collection optics are selected so that the unit cells of gratings are not resolved, the grating stacks are resolved and they appear to have a uniform color within the image of the overlay target.

A ceramic reference in conjunction with a spectrometer, a metallized ceramic material, and a method of utilizing a ceramic material as a reference in the ultraviolet, visible, near-infrared, or infrared spectral regions are presented. The preferred embodiments utilize a ceramic reference material to diffusely reflect incident source light toward a detector element for quantification in a reproducible fashion. Alternative embodiments metallize either the incident surface or back surface of to form a surface diffuse reflectance standard. Optional wavelength reference layers or protective layers may be added to the ceramic or to the metallized layer. The reference ceramic is used to provide a measure of optical signal of an analyzer as a function of the analyzers spatial, temporal, and environmental state.

A method and system are presented for determing a line profile in a patterned structure, aimed at controlling a process of manufacture of the structure. The patterned structure comprises a plurality of different layers, the pattern in the structure being formed by patterned regions and un-patterned regions. At least first and second measurements are carried out, each utilizing illumination of the structure with a broad wavelengths band of incident light directed on the structure at a certain angle of incidence, detection of spectral characteristics of light returned from the structure, and generation of measured data representative thereof. The measured data obtained with the first measurement is analyzed, and at least one parameter of the structure is thereby determined. Then, this determined parameter is utilized, while analyzing the measured data obtained with the second measurements enabling the determination of the profile of the structure.

Methods of detecting one or more parameters of a medium are disclosed. The methods include providing a waveguide grating device, contacting the waveguide grating with a medium, propagating a signal having at least one signal attribute through the waveguide, and comparing the modified signal attribute to a known signal attribute to detect a parameter of the medium.

A fluorescence detecting apparatus which allows highly precise measurement of fluorescence even with minute sample amounts, which has a strong responsiveness to temperature variations, which allows simultaneous measurement of a plurality of samples, and wherein the light source and the container holder, and the container holder and the fluorescence detector, are each optically connected by optical fibers; and the optical fibers are connected to the container holder in such a manner that the sample in the container is excited for fluorescence from below the sample container held by the container holder, and that they may receive the fluorescent light which is emitted by the sample from below the sample container.

A method and apparatus of diagnosing a cardiac disease state in as little as two minutes involving the utilization of an evanescent wave assay system in conjunction with a data acquisition and analysis procedure that monitors the precision of assay results in real time (i.e., while data is being acquired). The method includes diagnosing a disease state using a diagnostic procedure (e.g., an immunoassay) wherein the testing device informs the person conducting the test of the results of the test as soon as reliable test data is obtained (generally, <5% variation in the reaction rate of the assay). After which point, the diagnostic procedure may be terminated.

A hyperspectral imager that achieves accurate spectral and spatial resolution by using a micro-lens array as a series of field lenses, with each lens distributing a point in the image scene received through an objective lens across an area of a detector array forming a hyperspectral detector super-pixel. Each sub-pixel within a super-pixel has a bandpass or other type filter to pass a different band of the image spectrum. The micro-lens spatially corrects the focused image point to project the same image scene point onto all sub-pixels within a super-pixel. A color separator can be used to split the image into sub-bands, with each sub-band image projected onto a different spatially corrected detector array. A shaped limiting aperture can be used to isolate the image scene point within each super-pixels and minimize energy coupling to adjacent super-pixels.

A vehicle headlamp control method and apparatus includes providing an imaging sensor that senses light in spatially separated regions of a field of view forward of the vehicle. Light levels sensed in individual regions of the field of view are evaluated in order to identify light sources of interest, such as oncoming headlights and leading taillights. The vehicle's headlights are controlled in response to identifying such particular light sources or absence of such light sources. Spectral signatures of light sources may be examined in order to determine if the spectral signature matches that of particular light sources such as the spectral signatures of headlights or taillights. Sensed light levels may also be evaluated for their spatial distribution in order to identify light sources of interest.

In optical filter systems and optical transmission systems, an optical filter compresses data into and/or derives data from a light signal. The filter way weight an incident light signal by wavelength over a predetermined wavelength range according to a predetermined function so that the filter performs the dot product of the light signal and the function.

A hyperspectral imaging system, including: at least one hyperspectral imaging unit, including: at least one lens configured to direct light scattered by, reflected by, or transmitted through a target medium to at least one hyperspectral filter arrangement configured to separate the light into discrete spectral bands; an imaging sensor to: receive the discrete spectral bands from the at least one hyperspectral filter arrangement; detect light by a plurality of pixels for each of the spectral bands; and generate electrical signals based at least in part on at least a portion of the light; and at least one image processor in communication with the at least one imaging sensor and configured to generate hyperspectral image data associated with the target medium; and at least one processor configured to determine biological data based at least partially on at least a portion of the hyperspectral image data.

An interworking gateway for interworking an OMA IMPS domain and a SIMPLE domain comprises an OMA IMPS interface for communication with the OMA IMPS domain, a SIMPLE interface for communication with the SIMPLE domain and an interworking function linking the interfaces and comprising a transaction mapping module for converting an interworking subset of OMA IMPS transactions received by the OMA IMPS interface to corresponding SIMPLE transactions and relaying the corresponding SIMPLE transactions to the SIMPLE interface for transfer to the SIMPLE domain and for mapping an interworking subset of SIMPLE transactions received by the SIMPLE interface to corresponding OMA IMPS transactions and relaying the corresponding OMA IMPS transactions to the OMA IMPS interface for transfer to the OMA IMPS domain.

A sensor (200, 900) comprising an illuminator (212, 500, 804, 832, 858, 904), a receiver (216, 400, 420, 460, 480, 808, 836, 862, 924) and an analyzer (240) for detecting and identifying an analyte having a characteristic absorption band that is present in a sample region (208, 812, 824, 874, 922). The illuminator includes an illumination source (220) for illuminating the sample region with spectral energy across at least a portion of the characteristic absorption band. The receiver includes a detector (228, 404, 424, 460, 484, 866, 928) for sensing predetermined portions of the spectral energy band and for creating a sample spectral data vector (236). The analyzer uses the spectral data vector and known characteristic data to detect and identify the analyte.

Methods, systems and apparatus are provided for sorting particles in a stream of a sample in a flow cytometer by producing from a stable sort having desirable sort characteristics multiple images of a portion of the stream; generating from the multiple images an averaged numerical reference standard representative of the stable sort; continuously collecting during the sorting multiple running images of the portion of the stream; generating from the multiple running images at least one numerical sample average representative of the sample sort of each collection of the multiple running images; and comparing each numerical sample average to the numerical reference standard and determining whether a sample average exhibits a deviation from the reference standard that requires an adjustment of the sort. The sort may then be adjusted to eliminate or reduce the deviation and maintain the stable sort of the reference histogram. A novel imaging apparatus may be employed in a flow cytometer performing this method.

An apparatus is described for assessing plant status using biophysical and biochemical properties of the plant remotely sensed by the invention thereby allowing selective monitoring, elimination or treatment of individual plants. In a preferred embodiment, a single polychromatic emitter provides coincident light beams; one beam substantially in the visible portion of the spectrum (400 nm to 700 nm) and the other in the near infrared (NIR) portion of the spectrum (700 nm to 1100 nm). This light beam illuminates a small surface area on the ground, which may be bare ground, desired plants or undesired weeds. The beam of light may be focused, collimated or non-focused. A detector array, usually composed of a visible detector and a NIR detector, detects portions of this polychromatic light beam reflected by the surface area and provides a signal indicative of whether the detected light was reflected by a plant or by some non-plant object such as soil. A controller analyzes this signal and, assuming a plant is detected, responds by activating a device to take some action with respect to the plant or stores the analyzed signal with corresponding DGPS position in the controller's memory for later analysis. A number of actions may be taken by the controller. For instance, if the plant is a weed, the desired action might be to spray herbicide on the weed. Or, if the plant is a crop that is determined to be lacking in nutrient, the desired action may be to apply fertilizer. Additionally, if the plant under test is a turf landscape, such as found on golf courses and sporting fields, plant biomass may be mapped and geo-located using GPS for later, comparative analysis.

A model for determining the type of soil, the water content of a soil, and the soil properties, and a soil measurement data storage portion (60) to store therein measurement data necessary to carry out the model and correlated with specific measurement conditions are provided. The water content is measured by a water content measuring portion (57) on the basis of the measurement data fed from a soil sensor (S). The type of soil is determined by a feature extracting portion (56) and a type-of-soil determining portion (58), and the determined type of soil is sent to a determining portion (59). The determining portion (59) determines corresponding conditions and a model according to the type of soil and water content of the measured place received and sets them in a predetermined processing portion. The soil sensor feeds measurement data meeting the measurement conditions to a measurement information processing portion (55), and the processing portion (55) determines the soil properties according to the determined model.

A two-dimensional focal plane array (FPA) is divided into sub-arrays of rows and columns of pixels, each sub-array being responsive to light energy from a target object which has been separated by a spectral filter or other spectrum dividing element into a predetermined number of spectral bands. There is preferably one sub-array on the FPA for each predetermined spectral band. Each sub-array has its own read out channel to allow parallel and simultaneous readout of all sub-arrays of the array. The scene is scanned onto the array for simultaneous imaging of the terrain in many spectral bands. Time Delay and Integrate (TDI) techniques are used as a clocking mechanism within the sub-arrays to increase the signal to noise ratio (SNR) of the detected image. Additionally, the TDI length (i.e., number of rows of integration during the exposure) within each sub-array is adjustable to optimize and normalize the response of the photosensitive substrate to each spectral band. The array provides for parallel and simultaneous readout of each sub-array to increase the collection rate of the spectral imagery. All of these features serve to provide a substantial improvement in the area coverage of a hyperspectral imaging system while at the same time increasing the SNR of the detected spectral image.

A system for material excitation in microfluidic devices is described. Aspects of the invention resemble a submerged periscope when in use. They allow for light to be redirected along a more advantageous trajectory as does the maritime device. A prism with a reflecting surface may be used to direct a laser beam along one or more microfluidic trenches or channels. Alternatively, a reflecting surface may be provided in connection with a simple support. Directing a beam along multiple paths is preferably accomplished by scanning a single laser across or around the reflecting surface provided. Provision may be made for at least a portion of the submersible used to function as an electrode to assist in electrokinetically driving fluids and/or ions within the microfluidic device.

A flow cytometer includes an optical flow cell through which particles to be characterized on the basis of at least their respective side-scatter characteristics are caused to flow seriatim. A plane-polarized laser beam produced by a laser diode is used to irradiate the particles as they pass through a focused elliptical spot having its minor axis oriented parallel to the particle flow path. Initially, the plane of polarization of the laser beam extends perpendicular to the path of particles through the flow cell. A half-wave plate or the like is positioned in the laser beam path to rotate the plane of polarization of the laser beam so that it is aligned with the path of particles before it irradiated particles moving along such path.