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62 results about "Direct excitation" patented technology

Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources

Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains that direct excitation radiation to and emitted signals from such arrays and image the signals onto detector arrays, from which such signals may be subjected to additional processing.
Owner:PACIFIC BIOSCIENCES

Luminescence assay using cyclical excitation wavelength sequence

A method for the conduct of a measurement of proximity between luminescent species based on detection of transfer of excitation energy between them. A first photoluminescent species (the "donor") and a second photoluminescent species (the "acceptor") are provided and are such that the donor species and the acceptor species have at least some excitation spectral regions which differ and that at least a part of the emission spectrum of the donor overlaps with at least a part of the excitation spectrum of the acceptor. The donor species is excited with a cyclical temporal sequence of wavelength bands, optionally provided as pulses or modulated in intensity, giving rise to a characteristic temporal fluctuation in emission therefrom and emission in at least one wavelength band characteristic of the acceptor is analyzed to detect the presence of the said characteristic fluctuation or a subcomponent thereof and optionally also to detect a fluctuation characteristic of direct excitation of the acceptor.
Owner:PHOTONIC RES SYST

Apparatus and method for fabrication of nanostructures using multiple prongs of radiating energy

In one embodiment, an apparatus for fabricating nanostructure-based devices on a workpiece includes: a stage for supporting a workpiece, a radiating-energy source, and a feedstock delivery system. The workpiece has catalyst deposited thereon. The workpiece includes multiple work regions (e.g., dies). The feedstock delivery system is for delivery of feedstock gas to said catalyst. The feedstock delivery system is configured to directly heat catalyst on at least one die via simultaneously emitted multiple prongs of radiating energy. Preferably, the feedstock delivery system includes a feedstock heating system that is configured to heat the feedstock gas not merely by any global heating of a chamber containing the work region or any direct excitation of gas over the work region by the radiating energy.
Owner:ETAMOTA CORP

Multilens optical assembly for a diagnostic device

A diagnostics apparatus for detecting fluorescence events related to the presence of an analyte in a sample is disclosed. The apparatus includes a housing, a source of excitation light and a photodetector, and a unitary multi-surface optical module. The optical module is integrally formed and composed of an upstream portion having a focusing optical surface for directing excitation light from the light source to a focal region within an analyte-detection zone in the apparatus, and a downstream portion having a second focusing powered optical surface and at least one reflecting surface for directing fluorescence-emission light produced by fluorescence events within the detection zone, in a direction substantially normal to the path of the excitation light onto the photodetector. The optical module is adaptable to a variety of assay formats, including multiple-sample, sample-array, and disposable-cartridge formats.
Owner:QN DIAGNOSTICS LLC

Active type multipurpose protection mask

The invention provides an active type multipurpose protection mask which comprises a mask body. The body is a shell with the outer side being convex and the inner side being an inwards-concave cavity. A closed contact ring for covering the face of a person is arranged on the side of the inwards-concave cavity of the mask body in a secondary-primary clamping buckle embedded mode. A cover with the two sides being convex in an arc-shaped mode covers the convex outer side of the mask body in the same secondary-primary clamping buckle embedded mode. According to the active type multipurpose protection mask, active ventilation design is adopted, and thus mask breathing resistance is lowered; air holes are formed in the two sides of the mask body, heat exchange between the mask body and the exhaled air can be conducted, the inhaled air temperature is increased, and direct excitation of the cold air is lowered.
Owner:SHANGHAI LANGQIN INVESTMENT MANAGEMENT

Illumination system for an imaging apparatus with low profile output device

A fluorescence illumination system is provided for use with an imaging apparatus that defines a light-tight imaging compartment. The fluorescence illumination system includes a trans-illumination component configured to direct excitation light into a first surface of the specimen wherein diffused light emanates from a second surface thereof for receipt through the view port to acquire fluorescence data of the specimen. Further, the fluorescence illumination system includes an epi-illumination component configured to direct excitation light onto a third surface of the specimen wherein the diffused light exits the third surface thereof for receipt through the view port to acquire fluorescence data of the specimen.
Owner:XENOGEN CORP

Real-time fluorescent quantitation PCR (polymerase chain reaction) instrument

The invention provides a real-time fluorescent quantitation PCR (polymerase chain reaction) instrument, which comprises a light read head, wherein the light read head consists of at least two light detecting passages; each light detecting passage comprises an excitation light source, a dichroscope, an emitting light lens and a detecting device; after the excitation light of the excitation light source is directly irradiated on the dichroscope; after the light path direction is converted by the dichroscope, the excitation light is vertically irradiated onto a target of an EP pipe of a pipe to be detected; after the light reflected from the target of the EP pipe of the pipe to be detected sequentially passes through the dichroscope and the emitting light lens and then enters the detecting device for detection, wherein each light detecting passage shares the emitting light lens and the detecting device; the emitting light lens comprises a Fresnel lens. The light collecting efficiency of each light passage is approximate; the problem of spherical surface phase difference of a convex lens is effectively solved; the individual difference among the devices is eliminated by the same detecting device; through the arrangement of light path position, the cross interference among light paths is effectively avoided.
Owner:鲲鹏基因(北京)科技有限责任公司 +1

Methods of generating florescence resonance energy transfer (FRET) between semiconductor quantum dots and fluorescent dyes/proteins via multi-photon excitation, achieving zero background or direct excitation contributions to the fret signature

A system and method of sensing physiological conditions in biological applications includes a laser source for optically exciting a plurality of luminescent quantum dots and a plurality of biomolecules in a nanoscale sensing system having a nanocrystal structure, where the plurality of biomolecules is stained with dye. In a multi-photon excitation process, a laser system optically excites, the plurality of luminescent quantum dots and the plurality of biomolecules in the nanoscale sensing system, where fluorescence resonance energy transfer (FRET) occurs between the plurality of quantum dots and the plurality of biomolecules. Stability of self assembly of quantum dot peptide conjugates within the plurality of biomolecules is investigated. Physiological conditions at the cellular level are determined, using a spectrometer to sense fluorosence spectra. The sensing of physiological conditions includes transducing signals into immunoassays, clinical diagnostics and cellular imaging to provide treatment to biological subjects including human patients.
Owner:UNITED STATES OF AMERICA GOVT REPRESENTED BY THE SECRDETARY OF THE NAVY CHIEF OF NAVAL RES ONR NRL

Apparatus and method for fabrication of nanostructures using decoupled heating of constituents

In one embodiment, an apparatus for fabricating nanostructure-based devices on workpieces includes: a stage for supporting a workpiece, a radiating-energy source, and a feedstock delivery system. The workpiece has catalyst thereon. The radiating-energy source is configured to focus radiating energy toward a work region of the workpiece to directly heat catalyst at the work region, without directly heating catalyst at one or more other work regions of the workpiece. The feedstock delivery system delivers feedstock gas to the catalyst at the work region. The feedstock delivery system includes a feedstock heating system. The feedstock heating system is configured to heat the feedstock gas not merely by any global heating of the chamber or any direct excitation of gas over the work region by the focused radiating energy. Preferably, the radiating-energy source emits multiple prongs of radiating energy.
Owner:ATOMATE CORP

Method or measuring stress of heavy metals on plants by using plant micro-domain chlorophyll fluorescence method

InactiveCN104568887AGood consistency of photoelectric parametersLittle outside influenceFluorescence/phosphorescenceLuminous intensityPhotoluminescence
The invention belongs to the technical field of heavy metal pollution analysis and relates to a method or measuring stress of heavy metals on plants by using a plant micro-domain chlorophyll fluorescence method. The method comprises the following steps: putting plant leaves and quartz glass sheets in a shading box together, taking the representative part of to-be-measured plant leaves, regulating the temperature of a measuring environment to be 20 DEG C, selecting an xenon lamp as a plant fluorescence direct excitation source under shading or infrared conditions, adopting a parallel light source, and recording the photoluminescence intensity; and finally, determining the expression amount of plant leaves stressed or damaged by heavy metals. The method is simple in measurement process, reliable in design principle, convenient to use and operate, high in measurement accuracy, wide in application range and friendly in measurement environment.
Owner:SHANDONG NORMAL UNIV

Test system for testing damping performance of high-temperature material

The invention provides a test system for testing damping performance of a high-temperature material. The test system adopts a double-layer chamber structure comprising a high temperature vacuum chamber and a normal temperature vacuum chamber, wherein the high temperature vacuum chamber is used for heating a test piece (7); the normal temperature vacuum chamber is positioned below the high temperature vacuum chamber, and the high temperature vacuum chamber and the normal temperature vacuum chamber are communicated through a ring-shaped water cooling jacket (6); a shock exciting mechanism is positioned in the normal temperature vacuum chamber; a heating body (8) and a thermocouple (9) are arranged on an upper thermal insulation layer (13) and are communicated with an electric furnace control cabinet (29); and a data analysis system (24) and a data acquisition system (25) are connected with a displacement sensor (28) and an accelerometer (17) through data cables respectively. Because the double-lug cantilever beam test piece (7) is adopted, the contact damping influence due to direct excitation and the error due to the rotation of a central rigid block of the test piece are avoided, the test temperature of the test piece is changed, the air damping influence is eliminated, and the isolation of an electromagnetic vibration exciter and the high-temperature environment can be effectively realized; moreover, the test system also has the characteristics of simple structure, convenient use, and accurate and reliable test results.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Apparatus for scanning stimulable phosphor medium

A radiation image reading apparatus, including a cassette receiving section, a scanning section, an erase section, and a transport section. The cassette receiving section is adapted to receive a cassette housing a stimulable storage phosphor sheet. The transport section is adapted to transport the sheet along a substantially linear transport path to and from a travel end point in forward and reverse directions, respectively, through the scanning section and the erase section. The scanning section is coupled to the transport section and comprises: an excitation source for directing excitation energy of a first wavelength toward the sheet; a detector for receiving light excited from the sheet by the excitation energy; and a gimbaled mounting mechanism configured to register the scanning section to the surface of the sheet.
Owner:CARESTREAM HEALTH INC

Normal-pressure high-density microwave plasma shoe material surface treatment method

The invention provides a shoe material surface treatment method. The method includes cleaning the shoe material surface firstly with a cleaning agent so as to remove contaminants and other organic impurities residual on the shoe material surface; and treating the shoe material surface by utilization of a normal-pressure high-density microwave plasma technology so that a large amount of active groups are generated on the shoe material surface and the bonding strength of the shoe material and a binder is significantly enhanced. The normal-pressure high-density microwave plasma technology relates to direct excitation of air into high-density plasma torch by utilization of microwave in an air environment, and is free of any special gas, free of vacuumizing and free of heating. The normal-pressure high-density plasma torch directly acts on the shoe material surface to generate physical and chemical functions. The normal-pressure high-density plasma is high in density, and therefore the shoe material surface treatment is good in effects, high in speed, low in cost, and free of discharge of waste water, waste gas and solid waste. Surface treating agents with high toxicity to human bodies are replaced, thus improving the production environment and protecting health of production personnel.
Owner:SHIJIAZHUANG YOUSHENG MACHINERY EQUIP CO LTD

Electromagnetic Field Applicator Array with Integral Sensors for Implicit Correction of Mutual Coupling and Mismatch

The invention concerns a system for producing. specific field distributions in a defined volume or region. The system comprises an array of electromagnetic field generating elements each with an integrated sensor for measuring the phase and amplitude of the current flowing in a metallic element (antenna or coil) or field in a slot based element, a measurement device to enable measurement of both phase and amplitude of the electrical signals from the sensors with sufficient dynamic range for quantification of the signal, a multi channel radio frequency power source with individually controllable amplitude and phase to excite each of the electromagnetic field generating elements, and a feedback controller enabling controlled adjustment of the amplitude and phase of the radio frequency power source based on the signals from the sensors. The system controls the outputs of a multi channel radio frequency power source such that the current in a metallic or the field in a slot based electromagnetic field generating elements provide the desired electromagnetic field values and the superposition of the fields produced by each electromagnetic field generating element produces said specific electromagnetic field distribution in said defined volume or region. As the signal picked up by each sensor is directly related to the phase and amplitude of the current or field in the associated electromagnetic field generating element and hence the electromagnetic field generated by the array elements, where the current or field measured is the sum of both the applied (from the radio frequency power source) and secondary excitations from mutual coupling and reflections hence the measured value represents the ideal excitation in the absence of mutual coupling, reflections and mismatch. The feedback controller modifies the direct excitation such that the total excitation is the ideal array excitation without coupling or mismatch. The invention implicitly corrects for the coupling and mismatch without explicit knowledge of, and calculation based on, the mutual coupling and mismatch, termed the coupling matrix, such that changes in the coupling matrix due to presence of objects or changes thereof are inherently taken into account. Additionally, by sequentially exciting each element in turn the invention can directly determine the exact mutual coupling matrix of the array even in the presence of variations in source impedance and undefined cable lengths such that initial excitation amplitudes and phases can be calculated to allow rapid adjustment to the desired values. A particular application of interest is in radio frequency hyperthermia applicator systems.
Owner:FOUND OF RES ON INFORMATION TECH & SOC ITIS FOUND

Analyte-sensing device

An implantable unit includes fluorescent sensor molecules, each of which includes a binding site for an analyte, a donor fluorophore, and an acceptor fluorophore; and a first light source. An external system includes an external reading unit, which includes a light sensor; and a processor, which is configured to (i) during a first time period: (a) drive the first light source to generate light having a first illumination peak wavelength appropriate for excitation of the donor fluorophore, and (b) receive, from the light sensor, a first measurement of the fluorescent light emitted from the acceptor fluorophore, (ii) during a second time period: (a) drive a second light source to generate light having a second illumination peak wavelength appropriate for direct excitation of the acceptor fluorophore, and (b) receive, from the light sensor, a second measurement of the fluorescent light emitted from the acceptor fluorophore, and (iii) calculate the concentration of the analyte based on the measurements.
Owner:GLUSENSE LTD

Apparatus and methods relating to fluorescent optical switches

A fiber optic switching system which includes an optical switch having a movable actuator and a light fiber coupled to the actuator which terminates at an end target surface thereof for conducting excitation light from a light source to the optical switch mechanism. A flexible film or other surface whose response is conditioned to provide at least two different fluorescent surfaces is positioned such that an end surface of the actuator abuts or is placed in close proximity to the film throughout its movement from one position to another. A detector detects light emitted from the film. The actuator is movable so as to direct excitation light from the light fiber from the one fluorescent surface of the film to another and the detector detects light emitted from the film so as to determine which fluorescent surface of the film from which light has been emitted.
Owner:MACKINNON NICHOLAS B

Oil-based drilling fluid while-drilling lateral direction well-logging device and method

ActiveCN106761726ASolve the problem of current signal detectionIncrease the depth of formation detectionBorehole/well accessoriesCapacitanceWell logging
The invention discloses an oil-based drilling fluid while-drilling lateral direction well-logging device and method. The device comprises a sine alternating-current excitation source, a while-drilling lateral direction well-logging sensor, a signal collection module and a computer. An excitation mode based on electromagnetic induction principles is adopted to replace conventional direct excitation modes, so that limitation of the later is overcome; an equivalent circuit model for well-logging is built on the basis of capacitive coupling principles, and digital phase-sensitive demodulation technology is utilized to solve the problem of current signal detection when oil-based drilling fluid is used; button-shaped electrodes are adopted to detect strata in different directions, so that well-logging information like strata resistivity imaging in the process of drilling can be acquired. The device has the advantages of simple and reliable structure, high measuring accuracy and wide measuring range, and a method which can be used for reference is provided for well-logging while drilling under the condition of the oil-based drilling fluid.
Owner:ZHEJIANG UNIV

Microstrip filter having group hairclip structure for microwave communication

The microstrip filter is composed of input and output microstrips, first and last resonators of receiving direct excitation as well as multiple groups of hair clip type resonators with effective length in half wave length. In each group, number and direction of resonator are same, and directions are different between groups. Input and output microstrips in filter are connected to first and last resonators in filter directly. Couple between resonators is weak in same group since their directions are identical, and Couple between resonators in different groups is stronger. Thus, number of resonators is same group can be adjusted smartly in order to suite filter in different filters designed I different bandwidths. The invention is applicable to traditional plane type metal microstrip filer, also filter in high-temperature superconductor having high quality.
Owner:海泰超导通讯科技(天津)有限公司

Preparation method of organic crystalline material, organic crystalline material, and light-emitting element

The invention relates to the field of organic semiconductors, and particularly discloses a preparation method of an organic crystalline material, the organic crystalline material and a light-emittingelement. The preparation method of the organic crystalline material comprises the following steps: heating and annealing two oppositely stacked metal complex amorphous doped membranes in an inert environment, and then cooling to room temperature, wherein the host material of the metal complex amorphous doped membranes is a complex of a first metal and a first ligand, and the guest material is a complex of a second metal and a second ligand; moreover, the difference between the metal atomic numbers of the first metal and the second metal is greater than or equal to 10, and the first ligand andthe second ligand are the same or have spatially similar structures. According to the preparation method, the high-concentration doped defect-induced organic crystalline material can be obtained, thephotoluminescence spectrum of the prepared organic crystalline material has triplet state direct excitation and emission characteristics, and the organic crystalline material can be applied to a light-emitting element.
Owner:JIHUA LAB

Photo acoustic sample detector with background compensation

A photo acoustic detector for detecting a concentration of a sample in a sample mixture, the photo acoustic detector has a light source for producing a light beam for exciting molecules of the sample, a light modulator for modulating an intensity of the light beam for generating pressure variations in the sample mixture, an amplitude of the pressure variations being a measure of the concentration of the sample, and an acoustic cell with an acoustic resonator for amplifying the pressure variations. Furthermore, the photo acoustic detector has a resonant pickup element for converting the pressure variations inside the acoustic resonator into a detector signal, and a processing section for processing the detector signal to generate 1) a sample signal caused by the pressure variations, and 2) a background signal caused by direct excitation of the pickup element by the light beam. The acoustic cell and the pickup element are arranged in such a way that a phase difference between the background signal and the sample signal is close to 90 degrees.
Owner:KONINKLIJKE PHILIPS ELECTRONICS NV

Direct-excitation type angular displacement sensing metering device

The invention provides a direct-excitation type angular displacement sensing metering device, which comprises a connecting rod (11), a disc (12), a printed circuit board (PCB) (13), a metal sheet (14)and a power supply. One end of the connecting rod (11) is fixed to the circle center of the disc (12); the metal sheet (14) is fixedly arranged on the disc (12), and a straight line where the edge ofthe metal sheet (14) is located intersects with a straight line where the connecting rod (11) is located; the PCB (13) and the disc (12) are arranged in parallel at intervals; and the PCB (13) is electrically connected with the power supply. The PCB (13) comprises a coil layer (131) and a wiring layer (132). The coil layer (131) is composed of a plurality of induction coils, and the shape of thecoil layer (131) is the same as the shape of the disc (12); and a sampling circuit (15) for acquiring signals is arranged on a component layer (132). The metering device provided by the invention canprevent interference of an external magnetic field and can accurately meter the flow velocity or flow of liquid and gas.
Owner:长沙铨准电子科技有限公司

Electromagnetic speed regulator

An electromagnetic speed regulator comprises an electromagnetic speed regulator body and a direct current excitation circuit. The electromagnetic speed regulator body is composed of an inner rotor, an outer rotor, an inner rotor shaft, an outer rotor shaft, a bearing, a combined bearing, conductive sliding rings, electric brushes, a conductive wire, a rotating speed sensor, a machine shell and a machine base; the direct current excitation circuit is composed of a controllable rectification circuit, a current sensor, an electric reactor, a control circuit and a connection conductive wire. A fixed air gap is formed between the inner rotor and an iron core magnetic pole of the outer rotor. The two conductive sliding rings are arranged on an outer rotor supporting plate, and the two electric brushes make sliding contact with the surfaces of the two conductive sliding rings; the conductive sliding rings are connected with a concentrated winding of the outer rotor, and the positive output end and the negative output end of the direct excitation circuit are connected with the two electric brushes. The inner rotor shaft and the outer rotor shaft are connected through the combined bearing. The electromagnetic speed regulator has the advantages of replacing a frequency converter, and providing a motor speed regulation method achieving high efficiency, energy conservation, firmness, reliability, low cost, no-load starting and no electromagnetic interference.
Owner:杨玉岗

Single Analyte Molecule Detection by Fibre Fluorescemce Probe

An apparatus for single analyte molecule detection includes: a light source (20) for generating excitation light; a dichroic mirror (22) disposed on a first path of excitation light generated by the light source, wherein the mirror directs excitation light into a fiber aligner (30); an optical transducer coupled to the light source by the fiber aligner, the optical transducer comprising an optical waveguide (40) made of dielectric material having a first dielectrical index; a photon detector (70) disposed to receive fluorescent back radiation, wherein when a test solution having a second dielectric index lower than the first index is provided and comprises one or more target molecules, excitation light is transmitted by the waveguide and exits a waveguide tip disposed in the test solution so as to excite one or more target molecules; subsequently, the waveguide transmits back radiation along a second path to the photon detector that detects the transmitted back radiation.
Owner:BASEL UNIV OF

Modeling method of moment-limited hydraulic coupler-driven complex mechanical system

The invention relates to a modeling method related to a hydraulic coupler in a mechanical engineering field, in particular to a modeling method for a torque limited hydraulic coupler to drive a complex mechanical system. The modeling method for the torque limited hydraulic coupler to driving drive the complex mechanical system separates the mechanical system into two independent parts for the respective modeling and respectively treats a pump wheel and a turbine wheel of the hydraulic coupler. One independent part is that a motor is connected with the pump wheel of the hydraulic coupler and the other independent part is that the turbine wheel of the hydraulic coupler is connected with the mechanical system. Respective motion equations are constructed separately and motion amounts in the mechanical system are calculated according to the two equations. The modeling method of the invention avoids errors which are brought from a traditional direct excitation of an original characteristic curve on the mechanical system, thus leading to that the proposal design accords more correctly and comprehensively with the practical state of the mechanical system, and the correctness, the precision and the implementation efficiency of the design planning work of the whole mechanical system are improved.
Owner:SHANGHAI NORMAL UNIVERSITY

Nonlinear response regulation and control method based on continuous domain bound state of super-structure surface

ActiveCN113094959ARealize full manual controlEnhanced induced magnetic dipole momentDesign optimisation/simulationComputational theoretical chemistryFinite element analysis softwareEngineering
The invention discloses a regulation and control method based on super-structure surface continuous domain bound state nonlinear response. The regulation and control method comprises the following steps: 1, calculating physical parameters of artificial nonlinear response generated by BICs theoretically; 2, based on the obtained physical parameters influencing the nonlinear response, comparing and analyzing simulation results of the super-structure surface to the nonlinear response in two excitation modes of direct excitation and indirect excitation of BICs; 3, designing, processing and testing the nonlinear super-structure surface. According to the method, the metasurface is used as a theoretical design platform, finite element analysis software is used as calculation support, optical band near-field detection is used as a representation tool, the theoretical mechanism of efficient and artificial nonlinear response of the BICs and the regulation and control influence of all physical parameters of the metasurface on the nonlinear BICs are explored, the physical mechanism and the working mechanism contained in the artificial nonlinear BICs are revealed, full-manual, efficient and adjustable nonlinear response is achieved, and the industrial application requirements of nonlinear optical devices are met.
Owner:TIANJIN UNIV
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