1128results about "Burettes/pipettes" patented technology

The invention discloses a self-adaptive pipetting system and method based on multi-mode sensing fusion. The system comprises a PLC (Programmable Logic Controller), a fusion multi-mode sensing module, a high-throughput execution module, a self-adaptive protocol matching module and a man-machine interaction module. According to the invention, through multi-channel cooperation and continuous transmission, the experiment efficiency is greatly improved; multi-modal sensing data are fused, and real-time closed-loop control and dynamic compensation are performed by adopting algorithms such as fuzzy PID (Proportion Integration Differentiation) and the like, so that the pipetting volume precision reaches + / -1%, and the repeatability is improved by 20-30%; a protocol feature library and an intelligent matching algorithm are built in, and experimental parameters can be automatically analyzed, matched and optimized; equipment state and process parameters are monitored in real time, faults and pollution risks are automatically early warned, and the operation safety and reliability are remarkably improved in combination with automatic anti-pollution design; a PLC is deeply fused with a sensing module and a decision module, a sensing-decision-execution intelligent closed loop is constructed, and an accurate and reliable integrated solution is provided for automatic pipetting.

[Problem] To provide a powder supply device and a powder supply method in which surplus powder adhering to a suction measurement tool having a measuring chamber and a suction port can be removed by a simple process. [Solution] This powder supply device 1 comprises: a suction measurement tool 13 connected to a negative pressure source and having a measuring chamber 15, which is partitioned by a filter 14, and a suction port, which is provided at the tip; a nozzle 12 relatively moved by relative movement robots (501, 502, 503); and a powder removal brush 20 having brush bristles 22 extending in a direction crossing the vertical direction. The tip of the suction measurement tool 13 is embedded in the powder in a powder tank 101, and the powder is suctioned into the measuring chamber 15. After the powder is suctioned, surplus powder adhering to the suction measurement tool 13 is removed by relatively moving the suction measurement tool 13 and the brush bristles 22 while elastically deforming the brush bristles 22.

The utility model relates to the technical field of experimental equipment, and provides a reagent adding device which comprises a peristaltic assembly, an air pump, a first switch valve and a controller, the peristaltic assembly comprises a peristaltic pump, and an inlet of the peristaltic pump is communicated with a reagent bottle through an input pipe; an outlet of the peristaltic pump is communicated with the sample cup through an output pipe; an inlet of the air pump is communicated with air, and an outlet of the air pump is communicated with an inlet of the peristaltic pump through an exhaust pipeline; the first switch valve is arranged on the exhaust pipeline; the peristaltic pump, the air pump and the first switch valve are electrically connected with the controller, the controller controls the peristaltic pump to operate based on a target value, and after the target value is reached, the controller controls the peristaltic pump to stop, the air pump to start and controls the first switch valve to open. By controlling the operation of the peristaltic pump, the air pump and the first switch valve, the reagent adding amount can be accurately controlled, the reagent is prevented from being retained in the peristaltic pump and the output pipe, and the reliability and the accuracy of the reagent adding process are improved.

The sealing device comprises a first sealing assembly and a second sealing assembly, the first sealing assembly is arranged at the end, away from a gun head, of an inner cavity, the first sealing assembly comprises a sealing lantern ring, a first pressing plate and a first sealing ring, the sealing lantern ring is embedded in the inner cavity, and the first pressing plate is arranged on the first sealing ring. The first pressing plate is partially embedded in the inner cavity and abuts against the sealing lantern ring, the sealing lantern ring is in interference fit with the outer diameter of the piston rod, and the first sealing ring is arranged on the outer wall of the sealing lantern ring in a sleeving mode so as to apply radial pressing force to the sealing lantern ring; the second sealing assembly is arranged at the joint of the cylinder body and the gun head and comprises a second sealing ring, a second pressing plate and a push plate, the gun head is sleeved with the second sealing ring, the second pressing plate is embedded in the cylinder body and presses the gun head, and the push plate is connected to the cylinder body so as to press the second pressing plate. According to the technical scheme, the sealing effect and durability of the pipettor are improved.

Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins / toxins, viruses, DNA, and / or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect and identify. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.

A thermopneumatic interface includes one or more pneumatic inlet ports in fluid communication with one or more pneumatic outlet ports and a cooling loop extending through the thermopneumatic interface. The cooling loop is configured to maintain the thermopneumatic interface at a baseline temperature. The one or more pneumatic outlet ports are configured to contact a surface of a microfluidic chip. Each pneumatic inlet port is configured to receive a change in pressure and provide the change in pressure to a corresponding pneumatic outlet port. The thermopneumatic interface is configured to maintain the microfluidic chip at the baseline temperature.

The application discloses a liquid synchronous proportioning and sampling automation device and belongs to the technical field of laboratory automation equipment. The module comprises a mechanical execution unit and a control unit. The control unit stores individualized parameters of each container and executes a core uniform sampling algorithm: the volume of solute and solvent is calculated according to the target total amount and concentration ratio; the solvent liquid feeding time length is calculated at a set solvent speed; the required solute liquid feeding speed of the solute is inversely deduced according to the solvent liquid feeding time length; and finally, the solvent pump and the solute pump are controlled to synchronously operate at their respective speeds for the solvent liquid feeding time length, so that real-time uniform mixing and sampling are realized. The application integrates automatic cleaning, parameterized batch management, intermittent liquid feeding and other functions, solves the problems of low proportioning efficiency, uneven mixing, poor precision and easy cross contamination in the prior art, and realizes efficient, accurate and flexible automatic liquid filling.

The application relates to a dispensing device (9) which has: a dispensing unit (10) with at least one dispensing head (11) which has at least one dispensing nozzle arrangement (12) for filling at least one reaction vessel (2) of a reaction vessel unit (1) which can be translationally moved and positioned relative to the dispensing unit (10), wherein the reaction vessels (2) are designed in an approximately trough-like manner with approximately vertical peripheral walls (6), wherein the dispensing nozzle arrangement (12) is designed such that it is designed to discharge one or more dispensing jets (16) which extend at an angle with respect to the vertical (5, 5') such that they can be directed at an angle against one of the peripheral walls (6) of one of the reaction vessels (2). The dispensing device is characterised in that the one or more dispensing jets (16) have a jet pattern (17) extending in the peripheral direction (u) of the peripheral wall (6). The application also relates to a method for filling at least one reaction vessel (2) of a reaction vessel unit (1) by means of the dispensing device (9).

The present disclosure relates to a modified liquid handling system and related methods for collecting, separating, dispensing or otherwise conveying liquids, including a selected desired portion of a liquid sample, to a desired location. Several embodiments provided for herein relate to extraction of material of interest from layered, gradated, or partitioned, samples.

The application provides an injector, comprising an injector cavity, a push rod, a piston, an injection part and a cleaning branch pipe. The injection part is arranged at a first end of the injector cavity, a second end of the injector cavity is provided with a first opening, and the first end of the injector cavity is opposite to the second end of the injector cavity. The push rod is connected with the piston, and the push rod drives the piston to reciprocate in the injector cavity through the first opening. A side wall of the injector cavity is provided with a second opening, and the cleaning branch pipe communicates with the injector cavity through the second opening. When the injector is cleaned, the push rod drives the piston to move to a first space in a direction away from the injection part, so that the cleaning liquid flows into the injector cavity through the cleaning branch pipe and flows out from the injection part, and the first space is a space region between the first opening and the second opening. In this way, the cleaning liquid can flow in from the cleaning branch pipe and flow out from the injection part, without manually disassembling and cleaning the injector, and mechanical damage to the injector itself and the connecting components of the pipetting station is reduced.

The present invention relates to a mini-pipette, and more particularly, to a mini-pipette which has capacity varying means that can vary the movement distance of a push button reciprocating in the outer body to generate suction force so that a variety of samples can be easily collected. The present invention provides a mini-pipette comprising: an outer body having a hollow movement space and a suction passage formed at a lower part of the outer body; a push button for generating negative or positive pressure in the suction passage while reciprocating in the movement space of the outer body; elastic means for elastically supporting the push button in the movement space; and a capacity varying means formed inside the outer body, for varying a movement distance of the push button in the movement space.

A test tube extracting device relates to the technical field of medical treatment and comprises a supporting bottom plate, a protective shell arranged above the supporting bottom plate, a connecting rod fixedly connected to the front surface of the supporting bottom plate, a connecting shell arranged on the rear surface of the connecting rod, a belt arranged in the connecting shell, two pairs of cleaning brushes arranged below the connecting shell, and a fixing block arranged on the upper surface of the supporting bottom plate. The left surface of the fixing block is fixedly connected with a first connecting block, two pairs of test tube bodies are arranged in the connecting shell, a first clamping groove is formed in the lower surface of the first connecting block, and a limiting block is movably clamped in the first clamping groove. A second threaded rod is rotationally connected into the supporting bottom plate, bevel gears are fixed to the surfaces of the second threaded rod and the rotating rod, and the rotating rod drives the two bevel gears to be meshed with each other in the rotating process.

The utility model relates to medical supplies technical field, concretely relates to a kind of anti-pollution double-channel specimen transfer tube, including outer shell, the lower shell is arranged in the bottom of outer shell, fixedly connected with hose between the outer shell and lower shell, specimen warehouse body is fixedly connected in the inside of outer shell, the liquid inlet pipe is fixedly connected in the bottom of specimen warehouse body, the one-way duckbill valve is fixedly connected in the inside of liquid inlet pipe, by the extrusion of the hose, the fixed liquid stored in the cavity between outer shell and specimen warehouse body is unilaterally entered into the inside cavity of specimen warehouse body from liquid inlet pipe and one-way duckbill valve, completely immerse specimen warehouse body internal organization, the double-layer cavity structure formed by outer shell and specimen warehouse body, cooperate the extrusion function of the hose in bottom, realize the directional delivery of fixed liquid from the storage cavity between outer shell and specimen warehouse body to specimen warehouse body, solve the problem that traditional single-cavity pipe fixed liquid adds complicatedly, organization is not completely immersed.

The disclosure provides a kind of high viscosity microdroplet generation device and method based on three-dimensional microchannel structure, which is T-shaped, including first straight channel, vertical channel, second straight channel and third straight channel in turn;A group of boss structures are symmetrically provided inside the second straight channel near the two sides of the inner wall of the main channel, and the outer end face of the microtube can abut with the outer end face of the boss structure after extending into the vertical channel, so that high viscosity microdroplet generation channel is formed between the two boss structures;The connecting part of high viscosity microdroplet generation channel and third straight channel also forms a tapered channel, and high viscosity microdroplets are stably output from the third straight channel through the tapered channel;The present application designs a new tip mode, realizes the high monodispersity and uniformity of high viscosity microdroplets, size controllable, improves the stability of high viscosity microdroplet generation, and can be repeatedly used based on the detachable design of three-dimensional microchannel structure, which expands the application range of the technology.

The utility model mainly relates to general chemical or physical experiment equipment, in particular to a multi-channel pipette tip, which comprises a mounting shell with the top communicated with a pipette, linearly arranged mounting holes are arranged at the bottom of the mounting shell, pipette tip bodies are inserted into the mounting holes, first fixing rings are arranged on the pipette tip bodies, and the pipette tip bodies are provided with second fixing rings. Every two adjacent first fixing rings are fixedly connected through a first connecting piece. Mounting rings are arranged on the pipette tip bodies located at the two ends, the side walls of the mounting rings are fixedly connected with one ends of L-shaped rods, the other ends of the L-shaped rods are matched with inserting grooves formed in the bottoms of the mounting shells, sliding grooves are formed in one sides of the inserting grooves in a communicating mode, movable rods are slidably mounted in the sliding grooves, and clamping blocks are fixedly mounted at one ends of the movable rods; and the other end of the movable rod extends to the outer side of the mounting shell and is provided with a handle, a spring is arranged on the movable rod, and the two ends of the spring are connected with the mounting shell and the handle correspondingly.

The utility model discloses a pipette adapter and relates to the field of chemical analysis. The adapter is used for connecting a micropipettor at the upper end and a glass tube at the lower end. The adapter is mainly composed of a silica gel outer wall and a sand core filter arranged in the middle, and a cylindrical space with a certain diameter is reserved in the adapter. The adapter can be connected with glass tubes which are made of different materials and have various shapes, and halogenated hydrocarbon, ketone and aromatic hydrocarbon organic solvents can be accurately measured according to the characteristic.

The present application relates to the technical field of microfluidic chip, and disclose a centrifugal microfluidic chip for generating different size droplets simultaneously, including a liquid distribution channel for uniformly distributing sample to multiple droplet generation units, the design of a quantitative pool ensures the fixed volume of liquid and the consistency of the number of droplet generation, the chip contains a sample inlet and two continuous phase reagent inlets, the sample is precisely distributed to the quantitative pool by centrifugal force and enters the droplet generation units respectively, the first droplet generation unit is used for generating large size droplets with a diameter of 100-200 mu m, and the second droplet generation unit is used for generating small size droplets with a diameter of 10-100 mu m, the microfluidic chip can realize the preparation of ultrahigh throughput droplets, the generated droplets are guided to the collection area by centrifugal force to form a regular single-layer arrangement, the chip has wide application in the fields of biomedical research, material science, chemical synthesis and environmental monitoring, especially in the preparation of fluorescent microspheres, which can improve the experimental efficiency and result consistency.

The utility model discloses a multifunctional transfer device and a workstation, and relates to the technical field of molecular diagnosis. The multifunctional transfer device comprises a mounting frame, a liquid transfer part and a clamping transfer part. Wherein the liquid transferring component comprises a liquid transferring power assembly movably arranged on the mounting frame, and the liquid transferring component can move in the first linear direction through the liquid transferring power assembly to generate a liquid suction force or a liquid repelling force; the clamping transfer part comprises a plurality of clamping hands and a clamping hand driving motor, and the clamping hands are rotatably arranged on the mounting frame and are in transmission connection with the clamping hand driving motor; the liquid transfer part and the clamping hand driving motor are arranged side by side in the second linear direction perpendicular to the first linear direction; the liquid transfer part is arranged between the at least two clamping hands in a third linear direction perpendicular to the first linear direction. Therefore, the device has the advantages that the overall structure is compact, and the application range is wide.

The invention relates to a pipetting device for receiving and discharging a volume of fluid, comprising a pressing device, which has a pressing part and a pressing part housing, a rotatable setting device, which can be manually actuated by a user, for setting a pipetting volume of the pipetting device, a stop, and a coupling device, which is coupled to the setting device, the position of the stop can be set and the travel of the pressing element is determined, the displacement volume being defined by the travel of the pressing element, and a coupling device for coupling the setting device to the stop. The pipetting device has a protection mechanism for limiting the transmission of torque from the setting device to the coupling device such that the setting device is coupled to the coupling device when a threshold value of the torque acting on the setting device and / or a threshold value of the force acting on the setting device is below, the setting device moves together with the coupling device and, above the threshold value, reduces or interrupts the torque and / or force transmission.

A non-contact deposition system includes a jetting assembly including at least one microvalve. The microvalve includes an orifice plate defining an orifice therethrough. An actuation beam is disposed in spaced relation to the orifice plate. The actuation beam includes a base portion and a cantilever portion extending from the base portion toward the orifice and movable between a closed position and an open position. A seal structure including a sealing member is disposed at an overlap of the cantilever portion. A fluid manifold is coupled to the microvalve and defines a fluid reservoir containing a pressurized fluid. When the actuation beam is in the closed position, the cantilever portion is positioned such that the seal structure seals the orifice to close the microvalve, and in the open position, fluid is dispensed from the orifice toward a substrate and deposited thereon.

The utility model provides equipment capable of realizing multi-channel free pitch change and independent vertical movement, when the equipment is used, the transverse pitch change guide rail bottom plate can be fixed on a machine base, and if the multi-channel free pitch change needs to be realized, the transverse pitch change guide rail bottom plate is fixed; each pipettor mounting mechanism can be driven to move left and right through the respective transverse variable-pitch driving device, so that the distance between the pipettor mounting mechanisms can be adjusted; if the independent vertical movement needs to be realized, each pipettor mounting mechanism can drive the respective pipettor mounting seat to independently and vertically move through the respective vertical movement driving device, and after the pipettors are mounted, the independent vertical movement and the free spacing change of the plurality of pipettors can be realized through the operation. According to the utility model, the free distance change between the channels can be realized, and the independent vertical movement of each channel can be realized, so that the multi-channel pipettor arranged on the multi-channel pipettor can better meet the experiment requirements.

The invention discloses an ultrasonic pipetting device, and belongs to the field of liquid treatment and pipetting. Comprising a shell, the shell is provided with a mounting cavity and at least three openings communicated with the mounting cavity, the openings comprise an upper opening, a lower opening and a first lateral opening, and the upper opening is used for enabling liquid in the mounting cavity to overflow outwards to form overflow drainage liquid; the lower opening is used for enabling liquid in the mounting cavity to flow out downwards; and the piezoelectric ceramic is arranged in the mounting cavity, and the piezoelectric ceramic is configured to generate ultrasonic waves and transmit the ultrasonic waves to the liquid in the mounting cavity. The device has the beneficial effects that the ultrasonic effect is applied to the liquid in the mounting cavity through the piezoelectric ceramic, the flowing state of the liquid at the lower opening can be improved, liquid outlet is more continuous and more stable, and the occurrence probability of the phenomena such as uneven dripping, cutoff and back suction is reduced. The ultrasonic effect is beneficial to weakening the interference of bubbles on the flow channel / liquid outlet and reducing the flow fluctuation caused by bubble attachment and retention, so that the pipetting repeatability and the metering consistency are improved.

The invention relates to a transfer device (40) for inserting a pipette holder (41) into a pipetting device (42), comprising a comb structure (43) with a longitudinal strut (44) and a plurality of transverse struts (45, 46) arranged perpendicular to it, which are arranged parallel and equidistant from one another and which include two outer transverse struts (45) and several inner transverse struts (46) arranged between the outer transverse struts (45), wherein the longitudinal strut (44) and the two outer transverse struts (45) are formed in the form of a three-sided frame (47), wherein at least one inner transverse strut (46) has a greater length than at least one other inner transverse strut (46). The invention further relates to a transfer system (55) and a pipetting system (80).

The application discloses a single-channel pipette and a use method thereof, and particularly relates to the technical field of single-channel pipettes, which comprises an upper gun body and a lower gun body arranged at the bottom of the upper gun body, a protection connecting assembly is arranged between the upper gun body and the lower gun body, the protection connecting assembly comprises a center cylinder arranged in the upper gun body, and a piston cylinder is arranged at the bottom of the center cylinder and located outside the center cylinder. Through the corresponding cooperation of various structures, when the second limiting tooth and the first limiting tooth slide, a meshing sound with equal tooth spacing is emitted, which prompts the operator that the upper gun body and the lower gun body will reach a screwed state, the limiting buckle is clamped in the buckle cavity and emits an in-place sound, which prompts the operator that the screwing has reached the in-place state, the center cylinder cannot be continuously screwed, the operator is prevented from over-tightening the wire sleeve and causing the wire sleeve to burst, the hidden danger that the lower gun body falls off due to the bursting of the wire sleeve is prevented, and dangerous accidents caused by liquid leakage are avoided.

The invention relates to a handheld pipetting device, in particular with a touchscreen, a system comprising this pipetting device, a method, and program code. The operating concept of this pipetting device includes a function for the rapid mixing of samples by detecting user input via a mixing function input element, starting and executing the mixing process based on the input, and controlling the movement element during the mixing process such that a mixing step is performed or mixing steps are performed successively and counted by a parameter N_mix, wherein in each mixing step, the mixing volume VM of the sample is taken into the pipetting container by the corresponding movement of the movement element and subsequently dispensed again.

The utility model relates to the technical field of laboratory auxiliary tools, in particular to a combined dropper which comprises a supporting piece, a dropper head and a pressure adjusting piece. A slide way is arranged on the supporting piece; the water droppers are arranged on the supporting piece and communicated with the slide way, the number of the water droppers is at least two, and the at least two water droppers are arranged at intervals in the extension direction of the slide way; and the pressure adjusting piece is mounted on the slide way, is provided with a pressure adjusting opening used for being communicated with the water dropper, and is used for adjusting the pressure intensity in the water dropper. The supporting piece of the combined dropper is at least provided with the two water droppers, the water droppers are used for sampling, the pressure adjusting piece is matched with the water droppers through the supporting piece so as to drive the water droppers to suck a sample or discharge the sample, and the pressure adjusting piece can be switched to be matched with different water droppers so that one pressure adjusting piece can sequentially drive the multiple water droppers to sample; compared with a heavy device that one dropper is provided with one rubber ball head in the prior art, the combined dropper can achieve the purposes of reducing the number of devices and improving convenience.

The utility model relates to the technical field of pipette backflow prevention, in particular to a manual pipette liquid backflow prevention valve device, which comprises a first pipe body, a second pipe body, a third pipe body and a fourth pipe body, according to the utility model, the diaphragm can be pushed to descend by the air pressure generated by the operation of the pipette, and then the second piston is pushed to descend by the support plate and the second rod body, so that the air below the second piston in the negative pressure pipe is discharged through the one-way valve; if liquid rapidly flows back due to misoperation and other reasons, the liquid firstly enters the first pipe body and enters the annular shell through the porous structure at the bottom of the annular shell, the liquid is adsorbed through the sponge in the annular shell so that the liquid can be prevented from penetrating through the annular shell, and if the liquid is too much and penetrates through the annular shell, the liquid is prevented from flowing out of the annular shell. And liquid entering the position above the negative pressure pipe is buffered through negative pressure.

According to an example aspect of the present invention, there is provided an adapter for holding a pipette, the adapter comprising a body element, said body element configured to hold a pipette; wherein the adapter is configured to be attached to at least one rail at any point along the rail, said at least one rail comprising at least one electrical conductor, said electrical conductor extending at least partially along the length of the at least one rail.

A method for preparing an aliquot of solution is disclosed. The method includes agitating the solution with a baffle at a predetermined mixing speed to suspend the plurality of particles in the solution, wherein the baffle positioned at least partially within a vessel containing the solution, and wherein the vessel is engaged with a vessel receptacle configured to hold the vessel. The method also includes withdrawing, during the agitating, the aliquot of solution from the vessel with a pipette, such that an end of a pipette tip is positioned within the vessel.