26 results about "Fluidics" patented technology

The invention discloses a remote valve closing and locking mistaken opening prevention system based on an intelligent safety AI valve, and relates to the technical field of fluid control valves. The system comprises an intelligent sensing layer, a local decision-making layer and a cloud collaboration layer; the method comprises the following steps: constructing an AI valve network virtual model, integrating multiple groups of sensor data to obtain multi-modal data, acquiring an AI valve evaluation value in real time by utilizing a local decision-making layer, determining whether to generate a valve closing locking request according to the AI valve evaluation value, and constructing a three-channel parallel data transmission architecture. The cloud collaboration layer carries out fluid simulation and generates a visual display result when receiving the valve closing locking request, and an operator decides whether valve closing locking is carried out or not and carries out upstream and downstream linkage control; the valve closing error rate is reduced through multi-modal data fusion and AI valve network virtual model simulation, communication reliability is guaranteed through three data transmission channels, and accurate valve closing locking and accident range control are achieved through dynamic threshold adjustment.

A system and method for advancing a portion of a fluid in a first microfluidics card includes establishing a timed sequence of pressure condition events, each pressure condition event in the sequence creating one or more pressure differentials for either imparting to the portion of the fluid a moving force in which the portion is moved from a first to a second location, or establishing an equilibrium in which a position of the portion remains stationary. In certain embodiments, a fluidics processing unit is described. It includes a microfluidics card having an inlet line, an outlet line, and one or more microchannels in fluid communication with the inlet and outlet lines. It also includes at least one pressure source for driving fluid in the inlet and outlet lines, and a controller for actuating the at least one pressure source in a timed sequence of steps to selectively advance at least a portion of the fluid to one or more targeted locations through the microchannels.

A fluidic acoustic coupling system configured for management of fluids in histotripsy therapy is provided, which may include any number of features. Provided herein are systems and methods that provide management and control of fluid delivery and drainage of reservoirs within a fluidics cart of a histotripsy system. Additional embodiments are provided herein.

The invention discloses a microfluidic pre-focusing chip, and belongs to the technical field of microfluidics, the chip comprises a piezoelectric substrate, an interdigital transducer and a micro-cavity, the micro-cavity is bonded on the piezoelectric substrate, the micro-cavity comprises a main cavity channel, two ends of the main cavity channel are respectively provided with at least one sample input port and at least one sample output port, and the main cavity channel is connected with the interdigital transducer. The interdigital transducers are arranged on the piezoelectric substrate, located on the two sides of the main cavity channel respectively and arranged in the direction perpendicular to the flowing direction of a sample in the main cavity channel, the microcavity further comprises side cavity channels distributed on the two sides of the main cavity channel, filling liquid injection ports are formed in the side cavity channels, filling liquid is a liquid photocurable material, and the filling liquid injection ports are communicated with the main cavity channel. Meanwhile, the invention further discloses a design, manufacturing and application method of the chip, and the two-stage functions of pre-focusing and concentration can be effectively achieved under the sheath flow-free condition.

The invention relates to the technical field of fluid calculation, and discloses a gas release simulation calculation method, device and equipment for a pressure pipeline, and the method comprises the steps: building a constant flow initial model of the pressure pipeline; setting a gas-liquid two-phase flow initial condition, and calculating a gas-liquid two-phase flow parameter under the initial condition by using a bubble uniform distribution model; establishing a gas-containing gas-liquid two-phase flow finite volume method calculation equation; establishing a gas-liquid two-phase phase change gas release mathematical model, and calculating a gas phase mass change value by using the gas-liquid two-phase phase change gas release mathematical model; presetting a bubble average radius, and iteratively calculating a physical quantity; according to the method, a gas release equation is introduced, the limitation that single-phase flow and gas-liquid two-phase flow do not have low-pressure environment calculation conditions is broken through, the simulation calculation accuracy is improved, a simulation application scene is expanded from a gas-liquid two-phase flow high-pressure environment single-phase flow to a gas-liquid two-phase flow low-pressure environment complex working condition, and the simulation accuracy is improved. And a simulation calculation application scene is added.

The utility model relates to a jet flow type wind and rain simulation integrated device, relates to injection device field. Jet flow type wind and rain simulation integrated device includes bottom support, connects the connecting flange in bottom support top, is detachably connected through the bolt along the circumferential interval arrangement and is connected in the support seat of connecting flange top, connects the rotary seat in support seat top, connects the U shape's fan support in rotary seat top, can rotate and be connected in the fan of fan support along vertical plane, annular shower pipe and water pump connected in bottom support, and the outlet of shower pipe and fan is coaxial arrangement and is connected, and the inner wall of shower pipe is equipped with a plurality of shower holes along its circumferential interval arrangement, and the water inlet of water pump is connected with the water inlet pipe, and the water outlet of water pump is connected shower pipe through the water outlet pipe equipped with flow control valve, and the water outlet pipe is equipped with heater. Jet flow type wind and rain simulation integrated device can simulate the test of unmanned plane under different air temperature wind and rain environment, can increase the authenticity of different season training environment simulation.

The application relates to a micro-fluidic chip and application thereof, and belongs to the technical field of micro-fluidics. The micro-fluidic chip comprises a bottom plate layer and a cover plate layer in sealing cooperation with the bottom plate layer, a rotation center at the center of a circle is arranged on the bottom plate layer, and a sample pool, a transition flow channel, a detection unit, a balance flow channel and a waste pool are sequentially connected; the detection unit comprises a transition pool, a first flow channel, a first reaction pool, a second flow channel, a second reaction pool and a third flow channel which are sequentially connected; the transition flow channel and the balance flow channel are arranged around the rotation center; the transition flow channel is closer to the rotation center than the balance flow channel; and the detection unit is arranged in a region between the transition flow channel and the balance flow channel. A sample adding hole and a detection hole are arranged on the cover plate layer; the sample adding hole is located in correspondence with the sample pool; and the detection hole is located in correspondence with the second reaction pool. The micro-fluidic chip only needs to be matched with a simple mechanical structure, and can quickly complete nucleic acid RPA amplification and CRISPR accurate detection of various nucleic acid molecules including pathogenic bacteria under constant temperature by utilizing centrifugal force.

The application discloses a valve type micro-fluidic chip, and belongs to the field of micro-fluidics, which comprises a main body, the main body is provided with a storage area and a detection area, the main body is further provided with a first communication port and a second communication port, the first communication port is communicated with the storage area, the second communication port is communicated with the detection area, the valve type micro-fluidic chip further comprises a rotary valve, the rotary valve is provided with a communication groove, the rotary valve is rotatably installed on the main body, when the rotary valve rotates to a first position, the communication groove is communicated with the first communication port and the second communication port, so that the storage area is communicated with the detection area; when the rotary valve rotates to a second position, the communication groove is staggered with the first communication port and / or the second communication port, the storage area is disconnected with the detection area, through the above design, the on-off of the storage area and the detection area can be controlled by rotating the rotary valve, the operation is simple, and the overall structure of the chip is simple.

The present disclosure relates to a fluidics system with vacuum sampling. The fluidics system comprises a flow cell, a sampling subsystem, a sheath subsystem, a waste subsystem and a compressed air subsystem. The sampling subsystem is coupled with an inlet of the flow cell and provides sample fluid to the flow cell. The sheath subsystem is coupled with the inlet of the flow cell and provides sheath fluid to the flow cell. The waste subsystem is coupled with an outlet of the flow cell, and the sheath fluid and the sample fluid are discharged from the waste subsystem after passing through the outlet of the flow cell. The compressed air subsystem is coupled with the sheath subsystem and provides compressed air to the sheath subsystem. Further provided are a sample processor and a method for controlling a sample flow rate in the sample processor according to the present disclosure. The fluidics system, the sample processor and the method for controlling the sample flow rate in the sample processor according to the present disclosure can achieve significantly improved control accuracy.

An apparatus includes a reaction vessels coupled to an electronic sensor for monitoring a reaction product in the reaction vessel; a fluidics system for sequentially delivering a plurality of reagents to the reaction vessel, the fluidics system including a plurality of reagent reservoirs in fluidic communication via a plurality of flow paths with a fluidics circuit and to a common passage in fluidic communication between the fluidics circuit and the reaction vessel, a solution reservoir in fluidic communication with the common passage via a branch passage connected with the common passage at a junction between the fluidics circuit and the reaction vessel; and an electrode in contact with a solution within the branch passage, the electrode being in electrical communication with the reaction vessel through fluid extending from the branch passage and through the common passage, the electronic sensor generating an output signal depending on a voltage of the electrode.

The present invention relates to an integrated centrifugal device and method for analyte processing, particularly for the separation, enrichment, labeling, and analysis of nanovesicles such as extracellular vesicles (EVs). The device leverages a compact, rotatable substrate to execute multi-step assay protocols that may include chromatographic separation, centripetal fluid transport, immuno-capture, and protein labeling, all under low-speed centrifugal conditions. The device architecture enables automated, hands-free operation without requiring ultracentrifugation or specialized personnel. Fluidic modules including sedimentation, chromatography, displacement, and multiple assay chambers may be functionally integrated through a series of valves, channels, and immiscible liquid-based displacement mechanisms, facilitating precise sample handling, minimal loss, and multiplexed analysis.

Systems and methods are disclosed for measuring fluid pressure in an ophthalmic surgical system. An example system comprises a fluid flow path and a pressure sensor system for measuring pressure in the fluid flow path. The pressure sensor system comprises a conductive, movable diaphragm having a first side and a second side, the first side of the diaphragm facing the fluid flow path, and an eddy current position sensor positioned on the second side of the diaphragm without contacting the diaphragm. The eddy current position sensor comprises a position sensor coil activatable by high frequency alternating current and signal conditioning electronics capable of sensing inductance or impedance or resonant frequency variation in the position sensor coil as a gap between the diaphragm and the position sensor coil changes and of translating that variation into a displacement signal correlated to fluid pressure. A method of measuring fluid pressure may be performed using one or more of the systems described herein.

The handle of the endoscope may include a main body portion defining a first chamber having a first feature configured to support a first component of the steering assembly; and a second chamber having a second feature configured to support at least one fluid component (or fluidics component) or electronic component (or circuit board).

The invention provides a coupled jet flow quality detection device, a coupled jet flow quality detection method, a coupled jet flow quality detection system and a computer readable storage medium. The quality detection device for the coupling jet flow comprises a light-transmitting workpiece simulation piece which is located at the cross section position of the coupling jet flow; the first sensor is positioned below the light-transmitting workpiece simulation piece and is used for analyzing the light beam quality of the coupled jet flow; and the second sensor is positioned obliquely above the light-transmitting workpiece simulation piece and is used for acquiring image and / or video data of the coupled jet flow. According to the quality detection device for the coupling jet flow, the quality state of the light-water-gas coupling jet flow can be effectively detected, so that the situation that a machined workpiece is scrapped due to the stability problem of the coupling micro jet flow is avoided, the machining efficiency is improved, and losses generated by machining are reduced.

Systems for monitoring fluidics in reagent cartridges and related methods. An apparatus includes a system includes a reagent cartridge receptacle and a flow cell assembly. The apparatus includes a reagent cartridge receivable within the reagent cartridge receptacle and adapted to carry the flow cell assembly. The reagent cartridge includes a reagent reservoir fluidically coupled to the flow cell assembly. The apparatus includes a sensor module adapted to be positioned adjacent the reagent reservoir. The sensor module is adapted to generate a signal associated with a volume of reagent contained within the reagent reservoir.

This invention discloses a shaftless pump-jet mixing and conveying liquid preparation tank, belonging to the field of liquid preparation tank technology. It includes: a tank body and a lower head disposed at the bottom of the tank body; a shaftless pump-jet agitator disposed at the bottom of the lower head, comprising: a guide tube disposed at the lower head, the guide tube communicating with the inner cavity of the tank body through the lower head, the guide tube having a liquid outlet; a drive source and a stirring impeller, both installed inside the guide tube, the drive source located around the stirring impeller and the two connected by magnetic coupling for non-contact drive; when the stirring impeller rotates forward, it pumps the material in the lower head upward to the tank body for mixing; when the stirring impeller rotates in reverse, it pushes the material in the inner cavity of the tank downward to the liquid outlet for outward conveying. This application combines the outstanding advantages of shaftless motor propulsion technology with the low noise of pump-jet technology, which can both leverage the fluid dynamics advantages of pump-jet technology and eliminate shaft noise, thus having broad development prospects.

The present application relates to the technical field of gas explosion protection, and particularly relates to a jet field analysis method, a coordinate positioning method and a system based on mobile guide rail technology. The present application is based on the space axis symmetry theory and the boundary wave theory of gas leakage jet field, combined with remote control mobile technology and precise leakage field concentration testing technology, and proposes a jet field analysis method based on mobile guide rail technology; to realize accurate positioning, high reliability, without human intervention, thus reducing the experimental cost and improving the safety; can effectively avoid the existing technology, which generally adopts experimental test or data simulation, has a large deviation, low reliability and weak guiding significance for the actual scene; the analysis results are effectively used in the actual application of gas jet, to provide effective accident prevention measures for gas leakage, and to accurately obtain the jet field information at the same time of the accident, to determine the related information of the leakage point, and to timely and effectively position and rescue.

The jet-based ducted fan fluid thrust vector propulsion system belongs to the field of aviation power technology, and the system comprises an air inlet, a rotor, a stator and a tail nozzle arranged in series along an axis, and a duct flow channel is formed inside; a plurality of jet exciters in annular array distribution are embedded in the inner wall surface of the tail nozzle expansion section. The jet exciter is composed of a vibrating diaphragm and a resonance cavity, and an external control system outputs a high-frequency alternating signal to drive the vibrating diaphragm to vibrate at a high frequency, so that the gas in the cavity is periodically sucked and sprayed, forming a high-speed jet with zero net mass flow. The jet injects energy into the main flow boundary layer, induces the main flow to deflect based on the Coanda effect, and realizes omnidirectional thrust vector control. The present application does not need a mechanical deflection rudder surface and an external air source pipeline, has the advantages of compact structure, light weight, response without delay, low energy loss, and is suitable for electric vertical take-off and landing aircraft and tilting ducted fan propulsion systems.

The application discloses a micro-fluidic device for realizing a switch valve, and relates to the technical field of micro-fluidics.The micro-fluidic device comprises a fixed outer box, a micro-fluidic chip is fixedly installed on the lower surface of the fixed outer box, a door plate is rotatably installed on one side of the fixed outer box, a handle is fixedly installed on one side of the door plate, a visual window is also fixedly installed on one side of the door plate, and a through groove is formed in the other side of the fixed outer box; the rotating rod is rotated, the rotating rod rotates the cam, the cam vertically lowers the containing bottle through the fixed seat and the rack plate when the protruding position of the cam is in contact with the inner wall of the arc surface groove, the upper end of the inserted needle is inserted into the sealing plug and enters the cavity of the containing bottle along with the vertical lowering of the containing bottle, the fluid in the containing bottle enters the inside of the flow pipe through the inserted needle and flows out through the flow pipe, the micro-fluidic chip reads the flow rate and flow of the fluid at this time, and therefore, the micro-fluid control of the fluid is conveniently realized, and the convenience of the micro-fluid control of the fluid is effectively improved.

The utility model relates to the technical field of fluidics, specifically relates to a gas-liquid mixing fluidics, including connecting pipe, fluidic nozzle, conical part and adjusting mechanism, adjusting mechanism includes fixed base, support base, breather pipe, support plate, adjusting screw, cooperation mandrel and mounting device, the water flow passes through fluidic nozzle and enters to the inside of connecting pipe under the electrification operation of external water pump, the cross section area of fluidic nozzle position close to conical part gradually reduces, and then increases the water flow velocity, makes the vacuum area between conical part and the inner wall of connecting pipe, is convenient for making the outside air enter to the inside of connecting pipe, thereby convenient for making the outside ozone or other gas and water flow mix, the cooperation depth of breather pipe is adjusted through the rotation adjusting screw cooperation mandrel, makes the number of breather round hole ventilation work increase or reduce and realizes the adjustment to the air intake, thereby adjusts gas-liquid mixing ratio, and then can solve the existing gas-liquid mixing fluidics and is difficult to adjust gas water mixing ratio, and the problem of inconvenient use.

The utility model provides an acoustic streaming type liquid flow module, which comprises a rear shell provided with a first space for accommodating a circuit substrate and a second space for accommodating an interface; the circuit substrate is assembled at the position of the first space; a special ultrasonic device is arranged on one surface, back to the rear shell, of the circuit substrate; a micro-fluidic chip is tightly attached to the surface, back to the rear shell, of the special ultrasonic device, a micro-channel is formed in the micro-fluidic chip, and a liquid flow inlet and a liquid flow outlet which are communicated with the micro-channel are formed in the surface, back to the rear shell, of the micro-fluidic chip or the adjacent surface of the micro-fluidic chip; the acoustic fluid range of the special ultrasonic device comprises at least one part of the micro-channel; the interface is arranged at the position of the second space, is electrically connected with the special ultrasonic device through a circuit line on the circuit substrate, and is used for connecting a driving signal provided by an external driving device; and the front shell is assembled on the rear shell in a mode of shielding the interface. According to the application, the acoustic streaming type liquid flow modules with different functions can be conveniently replaced to the acoustic streaming type micro-fluidic system.

The utility model discloses a multi-stage coupling type efficient modular jet device which comprises a primary jet nozzle, a secondary jet acceleration ring and a third-stage mixing cavity which are connected in series, and jet modules are communicated through jet interstage transition sections. The butt joint end faces of the primary jet flow nozzle, the secondary jet flow accelerating ring and the third-stage mixing cavity are provided with quick-release flanges, a sealing ring set is embedded in an annular groove, and axial positioning is achieved through an interstage positioning pin. The outlet end of the third-stage mixing cavity is connected with a porous medium mixing layer and a diffusion pressurization cavity, the diffusion pressurization cavity is a conical diffusion section, and an outlet rectification grid is fixed at the outlet end of the diffusion pressurization cavity; the primary jet flow nozzle is provided with an opening quick connection end opening, a lateral liquid supplementing opening is formed in the side wall of the secondary jet flow accelerating ring, and an outlet flow dividing device is installed at the tail end of the outlet rectifying grid. According to the multi-stage modular jet device, efficient fluid mixing and conveying are achieved through the multi-stage modular design, and the maintainability and stability of the device are improved while the overall performance of the jet device is guaranteed.

Certain embodiments disclosed herein provide an ophthalmic surgical system. The system includes a fluidics module and a controller. The fluidics module includes a cartridge bay and one or more indicator lights. The one or more indicator lights correspond to one or more fluidic ports on the fluidics module. The controller includes a memory and a processor, the memory including executable instructions. The processor is in data communication with the memory. The processor is configured to execute the instructions to cause the system to: determine that a cartridge is coupled to the cartridge bay; determine a type of the cartridge; illuminate at least one of the one or more indicator lights based on the determined type of the cartridge; and extinguish the at least one of the one or more indicator lights upon receiving an input indicating that a fluidic conduit is fluidically coupled to a corresponding fluidic port.

The application discloses a disc type micro-fluidic chip and a sealing method, relates to the field of micro-fluidics, and solves the problems of poor sealing performance and complicated operation of the existing disc type micro-fluidic chip. The disc type micro-fluidic chip comprises 16 independent reaction detection structures which are uniformly distributed on the circumference of the disc type micro-fluidic chip. Each reaction detection structure comprises a V-shaped sample chamber, a horseshoe-shaped reagent chamber and a circular detection chamber. The V-shaped sample chambers are connected with each other and located on the side close to the center of the disc type micro-fluidic chip. Sample injection holes and air holes are arranged at the two ends of the V-shaped sample chambers. The horseshoe-shaped reagent chambers are independent of each other and located in the middle of the disc type micro-fluidic chip. Each horseshoe-shaped reagent chamber is provided with two liquid injection holes and air holes. The circular detection chambers are independent of each other and located on the outer periphery of the disc type micro-fluidic chip and used for mixing and reacting the sample and the reagent. The application provides two sealing modes of the disc type micro-fluidic chip and is also suitable for application fields such as nucleic acid detection.

The invention provides a propulsion device based on jet flow noise reduction, and belongs to the field of aircraft propulsion, and the propulsion device comprises an annular step arranged on the inner wall of a guide pipe; the propeller is arranged in the guide pipe; spouts are formed in the surfaces of the spherical nozzles; a plurality of grooves are formed in the annular side surface of the step around the propeller; the spherical nozzles are embedded in the grooves, hemispheres on one sides of the spherical nozzles are arranged in the grooves, hemispheres on the other sides of the spherical nozzles are located outside the grooves, the nozzles are formed in the hemispheres, located outside the grooves, of the spherical nozzles, the spherical nozzles conduct spherical rotation relative to the guide pipe, and the included angle between the direction of the nozzles and the axial direction of the propeller is changed. The spherical nozzle is embedded in the guide pipe, the orientation of the nozzle is changed through rotation of the sphere of the spherical nozzle, the included angle between the jet flow direction and the water flow direction in the propeller is adjusted, the blade tip gap vortex condition is adjusted, and then the noise condition generated by the blade tip gap vortex is improved.

The application discloses a method for generating a specific pattern by inducing particle adsorption based on micro-fluidic bubbles, and belongs to the fields of micro-fluidics and fluid mechanics.The method comprises the following steps: obtaining three-dimensional flow field data containing spatial position, corresponding velocity and phase field information; performing numerical simulation on particle motion based on the three-dimensional flow field data, calculating gravity, buoyancy, viscous resistance, van der Waals attraction, electrostatic repulsion, friction, wall support force and capillary force acting on the particle by judging the contact state of the particle with a wall surface and a gas-liquid interface; constructing a particle motion equation under the combined action of the above eight forces, updating the particle position and obtaining a migration track by using a time advancing method according to the motion equation; when the spherical surface of the particle is in contact with the solid wall surface, if the movement speed of the particle in the solid wall surface is consistent with the movement speed of the solid wall surface, it is determined that the particle has completed the transition from free motion to stable deposition, and the position of the particle at this time is recorded as a deposition site; and all the deposition sites are gathered into a specific pattern.